mebrofenin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| diagnostic aids; (phenylcarbamoyl)methyl iminodiacetic acid derivatives | 3332 | 78266-06-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Multiple use of single-use product | 186.78 | 115.90 | 21 | 35 | 1471 | 63487495 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Multiple use of single-use product | 270.62 | 141.66 | 28 | 43 | 896 | 79743421 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 1.35 | acidic |
| pKa2 | 2.54 | acidic |
| pKa3 | 12.95 | acidic |
| pKa4 | 7.72 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D04869 | KEGG_DRUG |
| 4038253 | VANDF |
| C1337345 | UMLSCUI |
| CHEMBL1605443 | ChEMBL_ID |
| DB15779 | DRUGBANK_ID |
| C000714007 | MESH_SUPPLEMENTAL_RECORD_UI |
| 54158 | PUBCHEM_CID |
| 5184 | INN_ID |
| 7PV0B6ED98 | UNII |
| 1311500 | RXNORM |
| 25101 | MMSL |
| d07088 | MMSL |
| 009840 | NDDF |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Choletec | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0270-0083 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 45 mg | INTRAVENOUS | NDA | 17 sections |
| Kit for the Preparation of Technetium Tc 99m Mebrofenin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45567-0455 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 45 mg | INTRAVENOUS | ANDA | 15 sections |
| Mebrofenin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51808-216 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 10 mg | INTRAVENOUS | Unapproved drug other | 5 sections |