mebrofenin Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
diagnostic aids; (phenylcarbamoyl)methyl iminodiacetic acid derivatives 3332 78266-06-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • mebrofenin
  • Molecular weight: 387.23
  • Formula: C15H19BrN2O5
  • CLOGP: 1.36
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 106.94
  • ALOGS: -3.83
  • ROTB: 7

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.35 acidic
pKa2 2.54 acidic
pKa3 12.95 acidic
pKa4 7.72 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C1337345 UMLSCUI
D04869 KEGG_DRUG
7PV0B6ED98 UNII
5184 INN_ID
4038253 VANDF
1311500 RXNORM
25101 MMSL
d07088 MMSL
009840 NDDF
CHEMBL1605443 ChEMBL_ID
54158 PUBCHEM_CID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Choletec HUMAN PRESCRIPTION DRUG LABEL 1 0270-0083 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 45 mg INTRAVENOUS NDA 11 sections
Kit for the Preparation of Technetium Tc 99m Mebrofenin HUMAN PRESCRIPTION DRUG LABEL 1 45567-0455 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 45 mg INTRAVENOUS ANDA 10 sections
Mebrofenin HUMAN PRESCRIPTION DRUG LABEL 1 51808-216 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 10 mg INTRAVENOUS Unapproved drug other 5 sections