inosine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antivirals 3301 58-63-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • inosine
  • 9-beta-D-Ribofuranosylhypoxanthine
  • hypoxanthine ribonucleoside
  • hypoxanthine riboside
  • hypoxanthosine
  • oxiamin
  • ribonosine
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)
  • Molecular weight: 268.23
  • Formula: C10H12N4O5
  • CLOGP: -2.31
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 4
  • TPSA: 129.20
  • ALOGS: -1.29
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D06BB05 DERMATOLOGICALS
ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
CHEMOTHERAPEUTICS FOR TOPICAL USE
Antivirals
ATC G01AX02 GENITO URINARY SYSTEM AND SEX HORMONES
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Other antiinfectives and antiseptics
ATC S01XA10 SENSORY ORGANS
OPHTHALMOLOGICALS
OTHER OPHTHALMOLOGICALS
Other ophthalmologicals
CHEBI has role CHEBI:75771 Mus musculus metabolites
CHEBI has role CHEBI:75772 S. cerevisiae metabolites
CHEBI has role CHEBI:76971 Escherichia coli metabolites
CHEBI has role CHEBI:77746 Homo sapiens metabolite

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.84 acidic
pKa2 11.67 acidic
pKa3 12.25 acidic
pKa4 12.95 acidic
pKa5 1.08 Basic
pKa6 0.14 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000008090 NUI
D00054 KEGG_DRUG
C0021528 UMLSCUI
CHEBI:17596 CHEBI
NOS PDB_CHEM_ID
CHEMBL1556 ChEMBL_ID
DB04335 DRUGBANK_ID
D007288 MESH_DESCRIPTOR_UI
135398641 PUBCHEM_CID
4554 IUPHAR_LIGAND_ID
4687 INN_ID
5A614L51CT UNII
1483575 RXNORM
003901 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Rejuvesol HUMAN PRESCRIPTION DRUG LABEL 5 23731-7000 SOLUTION 1.34 g EXTRACORPOREAL NDA 11 sections
Rejuvesol HUMAN PRESCRIPTION DRUG LABEL 5 23731-7000 SOLUTION 1.34 g EXTRACORPOREAL NDA 11 sections