hydrogen peroxide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3281 7722-84-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxydol
  • hydrogen peroxide topical solution
  • hydrogen peroxide
A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
  • Molecular weight: 34.01
  • Formula: H2O2
  • CLOGP:
  • LIPINSKI: None
  • HAC: 2
  • HDO: 2
  • TPSA: 40.46
  • ALOGS:
  • ROTB: 0

Drug dosage:

DoseUnitRoute
60 mg O

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Completed suicide 5679.22 23.84 1957 14497 129932 50458738
Toxicity to various agents 3403.08 23.84 1548 14906 210951 50377719
Drug abuse 1637.56 23.84 643 15811 59203 50529467
Intentional overdose 1174.28 23.84 514 15940 61990 50526680
Cardio-respiratory arrest 1143.06 23.84 483 15971 53409 50535261
Overdose 843.94 23.84 477 15977 99250 50489420
Suicide attempt 693.11 23.84 337 16117 51395 50537275
Alcohol interaction 488.63 23.84 118 16336 2026 50586644
Suspected suicide 419.96 23.84 127 16327 5230 50583440
Respiratory arrest 326.36 23.84 170 16284 29839 50558831
Intentional product misuse 321.39 23.84 196 16258 46538 50542132
Cardiac arrest 289.49 23.84 230 16224 83421 50505249
Alcohol poisoning 260.84 23.84 69 16385 1731 50586939
Alcohol use 235.24 23.84 65 16389 1930 50586740
Death 232.40 23.84 394 16060 324985 50263685
Coma 202.18 23.84 159 16295 56720 50531950
Alcohol abuse 183.63 23.84 53 16401 1848 50586822
Somnolence 181.39 23.84 237 16217 154748 50433922
Drug ineffective 159.98 23.84 36 16418 819297 49769373
Exposure to toxic agent 145.71 23.84 52 16402 3606 50585064
Loss of consciousness 108.79 23.84 151 16303 104202 50484468
Poisoning deliberate 103.98 23.84 51 16403 7861 50580809
Mydriasis 97.98 23.84 54 16400 10573 50578097
Blood alcohol increased 92.03 23.84 24 16430 568 50588102
Agitation 90.93 23.84 99 16355 53285 50535385
Pain 90.12 23.84 38 16416 578865 50009805
Diarrhoea 87.87 23.84 41 16413 588435 50000235
Alcoholism 87.79 23.84 29 16425 1591 50587079
Intentional self-injury 85.02 23.84 66 16388 23046 50565624
Postmortem blood drug level abnormal 83.06 23.84 20 16434 338 50588332
Arthralgia 81.86 23.84 21 16433 438681 50149989
Fatigue 81.23 23.84 67 16387 707534 49881136
Substance abuse 80.55 23.84 35 16419 4089 50584581
Dyspnoea 78.91 23.84 40 16414 547568 50041102
Rash 74.20 23.84 25 16429 437446 50151224
Poisoning 67.55 23.84 45 16409 12384 50576286
Drug use disorder 66.36 23.84 28 16426 3044 50585626
Drug dependence 65.33 23.84 53 16401 19706 50568964
Myocarditis 64.10 23.84 37 16417 7910 50580760
Joint swelling 61.08 23.84 5 16449 245281 50343389
Aggression 60.21 23.84 52 16402 21064 50567606
Seizure 60.15 23.84 124 16330 117750 50470920
Liver injury 58.72 23.84 55 16399 24751 50563919
Drug withdrawal syndrome 58.20 23.84 55 16399 25026 50563644
Suicidal ideation 57.42 23.84 80 16374 55305 50533365
Victim of sexual abuse 56.95 23.84 16 16438 505 50588165
Alopecia 55.81 23.84 7 16447 245040 50343630
Condition aggravated 55.76 23.84 14 16440 297044 50291626
Depressed level of consciousness 55.29 23.84 76 16378 51877 50536793
Headache 54.31 23.84 51 16403 506484 50082186
Off label use 54.18 23.84 45 16409 474381 50114289
Drug interaction 53.22 23.84 164 16290 199457 50389213
Pneumonia 52.40 23.84 29 16425 378372 50210298
Pruritus 52.00 23.84 14 16440 283554 50305116
Pain in extremity 50.93 23.84 13 16441 272852 50315818
Drug intolerance 48.13 23.84 7 16447 219097 50369573
Swelling 47.58 23.84 5 16449 200867 50387803
Tachycardia 45.16 23.84 100 16354 99663 50489007
Hypersensitivity 44.73 23.84 8 16446 215153 50373517
Pyrexia 43.44 23.84 36 16418 380167 50208503
Abdominal discomfort 43.28 23.84 11 16443 231630 50357040
Sopor 43.11 23.84 42 16412 19837 50568833
Somnambulism 42.59 23.84 24 16430 4900 50583770
Electrocardiogram QT prolonged 42.35 23.84 67 16387 51819 50536851
Peripheral swelling 42.07 23.84 8 16446 205928 50382742
Chemical submission 40.93 23.84 10 16444 180 50588490
Asphyxia 40.42 23.84 24 16430 5403 50583267
Metabolic acidosis 40.11 23.84 56 16398 38769 50549901
Back pain 40.06 23.84 11 16443 220019 50368651
Urinary tract infection 39.31 23.84 12 16442 224008 50364662
Nausea 38.97 23.84 110 16344 705288 49883382
Anaemia 38.45 23.84 17 16437 252439 50336231
Hypertrophic scar 38.03 23.84 6 16448 6 50588664
Asthenia 36.68 23.84 30 16424 319012 50269658
Electrocardiogram QRS complex prolonged 35.60 23.84 22 16432 5322 50583348
Drug hypersensitivity 35.04 23.84 19 16435 250991 50337679
Protein C increased 34.69 23.84 8 16446 111 50588559
Nasopharyngitis 34.45 23.84 10 16444 192917 50395753
Homicide 34.27 23.84 10 16444 362 50588308
Sinusitis 34.04 23.84 7 16447 170551 50418119
Amnesia 33.70 23.84 54 16400 42206 50546464
Infection 32.71 23.84 8 16446 172946 50415724
Product dose omission issue 31.97 23.84 10 16444 183828 50404842
Ventricular tachycardia 31.66 23.84 32 16422 15789 50572881
Cough 31.22 23.84 20 16434 241244 50347426
Abnormal behaviour 30.93 23.84 35 16419 19623 50569047
Substance dependence 30.41 23.84 8 16446 196 50588474
Weight increased 30.09 23.84 14 16440 201877 50386793
Neutropenia 29.67 23.84 6 16448 147959 50440711
Induced abortion failed 29.29 23.84 8 16446 227 50588443
Hypotension 28.98 23.84 152 16302 235317 50353353
Sinus tachycardia 28.58 23.84 35 16419 21319 50567351
Accidental death 28.29 23.84 13 16441 1731 50586939
Road traffic accident 27.99 23.84 37 16417 24315 50564355
Shock 27.89 23.84 34 16420 20616 50568054
Application site discolouration 27.38 23.84 10 16444 740 50587930
Malaise 27.14 23.84 42 16412 335490 50253180
Congenital umbilical hernia 27.02 23.84 8 16446 305 50588365
Disinhibition 26.63 23.84 10 16444 800 50587870
Therapeutic product effect decreased 26.29 23.84 6 16448 136044 50452626
Constipation 25.99 23.84 14 16440 185694 50402976
Unresponsive to stimuli 25.62 23.84 40 16414 30569 50558101
Hepatic failure 25.39 23.84 41 16413 32242 50556428
Respiratory depression 25.33 23.84 25 16429 11985 50576685
Areflexia 25.27 23.84 14 16440 2766 50585904
Euphoric mood 25.26 23.84 16 16438 4039 50584631
Electrocardiogram ST segment elevation 24.93 23.84 15 16439 3458 50585212
Postmortem blood drug level 24.51 23.84 6 16448 109 50588561
Blood ethanol increased 24.30 23.84 6 16448 113 50588557
Alcoholic 24.19 23.84 5 16449 40 50588630
Musculoskeletal stiffness 24.17 23.84 6 16448 128475 50460195

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug abuse 4246.06 23.36 1686 18217 78197 29476427
Completed suicide 3632.51 23.36 1563 18340 88683 29465941
Toxicity to various agents 3236.64 23.36 1773 18130 171888 29382736
Intentional overdose 807.69 23.36 430 19473 38098 29516526
Cardio-respiratory arrest 773.55 23.36 459 19444 50142 29504482
Overdose 616.33 23.36 474 19429 79345 29475279
Alcohol abuse 545.21 23.36 175 19728 4158 29550466
Alcohol interaction 509.80 23.36 149 19754 2554 29552070
Suicide attempt 495.97 23.36 300 19603 33810 29520814
Intentional product misuse 478.73 23.36 295 19608 34366 29520258
Suspected suicide 368.77 23.36 128 19775 3892 29550732
Substance abuse 286.99 23.36 123 19780 6664 29547960
Alcohol poisoning 281.92 23.36 98 19805 2991 29551633
Drug dependence 272.73 23.36 172 19731 20809 29533815
Respiratory arrest 186.77 23.36 148 19755 25685 29528939
Aggression 183.93 23.36 168 19735 35373 29519251
Coma 180.23 23.36 174 19729 39276 29515348
Alcohol use 173.93 23.36 69 19834 3063 29551561
Respiratory depression 158.68 23.36 104 19799 13419 29541205
Poisoning deliberate 148.59 23.36 74 19829 5657 29548967
Exposure to toxic agent 136.97 23.36 55 19848 2520 29552104
Asphyxia 130.08 23.36 66 19837 5249 29549375
Intentional product use issue 117.70 23.36 144 19759 42354 29512270
Diarrhoea 115.86 23.36 40 19863 332658 29221966
Cardiac arrest 114.67 23.36 206 19697 85385 29469239
Drug ineffective 112.87 23.36 52 19851 363118 29191506
Incorrect route of product administration 112.13 23.36 77 19826 10724 29543900
Pneumonia 108.89 23.36 40 19863 320132 29234492
Blood alcohol increased 106.36 23.36 33 19870 697 29553927
Anaemia 92.17 23.36 13 19890 200938 29353686
Poisoning 87.00 23.36 64 19839 9929 29544695
Pyrexia 86.45 23.36 43 19860 287579 29267045
Suicidal ideation 82.43 23.36 109 19794 34607 29520017
Drug withdrawal syndrome 79.55 23.36 78 19825 17906 29536718
Intentional self-injury 76.58 23.36 65 19838 12396 29542228
Dyspnoea 76.28 23.36 65 19838 326667 29227957
Alcohol withdrawal syndrome 75.35 23.36 30 19873 1343 29553281
Rash 74.77 23.36 18 19885 189801 29364823
Fatigue 73.98 23.36 63 19840 316758 29237866
Sopor 73.34 23.36 60 19843 10874 29543750
Death 65.50 23.36 423 19480 341661 29212963
Drug use disorder 59.86 23.36 34 19869 3388 29551236
Neutropenia 59.21 23.36 9 19894 131702 29422922
Miosis 58.06 23.36 46 19857 7963 29546661
Drug interaction 56.99 23.36 273 19630 197112 29357512
Agitation 55.66 23.36 113 19790 51191 29503433
Medication error 55.65 23.36 70 19833 21141 29533483
Arthralgia 55.41 23.36 13 19890 139604 29415020
Off label use 55.40 23.36 73 19830 300727 29253897
Road traffic accident 55.27 23.36 60 19843 15501 29539123
Febrile neutropenia 52.00 23.36 7 19896 112233 29442391
Sepsis 51.51 23.36 16 19887 142666 29411958
Drug screen positive 51.43 23.36 32 19871 3769 29550855
Accidental death 50.94 23.36 26 19877 2092 29552532
Alcoholism 50.80 23.36 28 19875 2633 29551991
Alcohol intolerance 49.83 23.36 16 19887 379 29554245
Tachycardia 48.44 23.36 132 19771 72278 29482346
Cough 47.96 23.36 13 19890 126714 29427910
Constipation 46.55 23.36 10 19893 114150 29440474
Pain 46.51 23.36 29 19874 171403 29383221
Mydriasis 46.38 23.36 36 19867 6049 29548575
Hepatic fibrosis 45.58 23.36 28 19875 3224 29551400
Haemoglobin decreased 45.21 23.36 9 19894 108366 29446258
Ex-drug abuser 45.13 23.36 12 19891 142 29554482
Pruritus 44.19 23.36 12 19891 116837 29437787
Amnesia 43.14 23.36 64 19839 22579 29532045
Asthenia 42.98 23.36 49 19854 215201 29339423
Condition aggravated 42.15 23.36 23 19880 146272 29408352
Depressed level of consciousness 42.01 23.36 83 19820 36859 29517765
Somnolence 41.28 23.36 148 19755 93807 29460817
Pain in extremity 40.54 23.36 12 19891 110421 29444203
Back pain 37.75 23.36 11 19892 102273 29452351
Impaired driving ability 37.68 23.36 22 19881 2309 29552315
White blood cell count decreased 36.75 23.36 6 19897 83356 29471268
Drug abuser 36.70 23.36 26 19877 3801 29550823
Withdrawal syndrome 36.64 23.36 41 19862 10951 29543673
Loss of consciousness 36.29 23.36 121 19782 73935 29480689
Decreased appetite 36.18 23.36 27 19876 145315 29409309
Dysarthria 35.80 23.36 70 19833 30841 29523783
Malignant neoplasm progression 35.68 23.36 4 19899 73855 29480769
Pulmonary oedema 34.87 23.36 84 19819 42651 29511973
Product dose omission issue 34.42 23.36 11 19892 96372 29458252
Homicide 33.31 23.36 15 19888 913 29553711
Oedema peripheral 33.30 23.36 14 19889 103543 29451081
Nausea 33.23 23.36 93 19810 289162 29265462
General physical health deterioration 32.92 23.36 14 19889 102843 29451781
Platelet count decreased 32.32 23.36 15 19888 104657 29449967
Foetal alcohol syndrome 31.82 23.36 9 19894 136 29554488
Metabolic acidosis 30.69 23.36 74 19829 37588 29517036
Pancytopenia 30.58 23.36 9 19894 83159 29471465
Weight decreased 30.47 23.36 34 19869 150871 29403753
Peripheral swelling 29.44 23.36 4 19899 63735 29490889
Cardiac failure 28.39 23.36 9 19894 79278 29475346
Myocardial fibrosis 28.29 23.36 14 19889 1054 29553570
Physical assault 28.10 23.36 14 19889 1070 29553554
Opiates positive 27.24 23.36 11 19892 511 29554113
Nasopharyngitis 26.96 23.36 4 19899 59661 29494963
Thrombocytopenia 26.53 23.36 31 19872 134792 29419832
Sensorimotor disorder 26.20 23.36 10 19893 399 29554225
Deep vein thrombosis 25.59 23.36 4 19899 57395 29497229
Myocardial infarction 25.54 23.36 22 19881 110274 29444350
Shock 25.43 23.36 49 19854 21355 29533269
Brain oedema 25.40 23.36 36 19867 12184 29542440
Cardiac failure congestive 25.18 23.36 10 19893 76571 29478053
Gun shot wound 25.17 23.36 13 19890 1072 29553552
Abdominal pain 24.67 23.36 33 19870 135324 29419300
Urinary tract infection 24.54 23.36 9 19894 72345 29482279
Septic shock 24.44 23.36 6 19897 62554 29492070
Dextrocardia 24.26 23.36 7 19896 114 29554510
Cerebrovascular accident 23.77 23.36 11 19892 76900 29477724

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Completed suicide 8727.79 21.64 3476 29001 220938 64245317
Toxicity to various agents 6373.36 21.64 3230 29247 360283 64105972
Drug abuse 5709.73 21.64 2222 30255 130152 64336103
Cardio-respiratory arrest 1870.52 21.64 934 31543 97459 64368796
Intentional overdose 1571.67 21.64 807 31670 89137 64377118
Overdose 1180.73 21.64 823 31654 158743 64307512
Alcohol interaction 826.83 21.64 227 32250 4174 64462081
Intentional product misuse 758.79 21.64 465 32012 71830 64394425
Suicide attempt 743.39 21.64 456 32021 70551 64395704
Suspected suicide 711.28 21.64 236 32241 8418 64457837
Alcohol abuse 549.86 21.64 169 32308 4683 64461572
Respiratory arrest 483.18 21.64 312 32165 52673 64413582
Alcohol poisoning 435.07 21.64 137 32340 4118 64462137
Cardiac arrest 367.07 21.64 419 32058 153645 64312610
Death 343.29 21.64 751 31726 481954 63984301
Alcohol use 336.54 21.64 115 32362 4487 64461768
Coma 333.77 21.64 307 32170 87308 64378947
Substance abuse 307.11 21.64 130 32347 9162 64457093
Drug dependence 300.64 21.64 195 32282 33117 64433138
Exposure to toxic agent 268.09 21.64 105 32372 6054 64460201
Drug ineffective 236.45 21.64 66 32411 840181 63626074
Poisoning deliberate 234.74 21.64 121 32356 13337 64452918
Diarrhoea 186.60 21.64 66 32411 722638 63743617
Aggression 185.66 21.64 167 32310 46065 64420190
Blood alcohol increased 172.18 21.64 50 32427 1132 64465123
Dyspnoea 149.19 21.64 89 32388 718585 63747670
Fatigue 145.49 21.64 100 32377 748630 63717625
Pain 143.61 21.64 50 32427 553461 63912794
Respiratory depression 136.42 21.64 105 32372 23338 64442917
Arthralgia 135.16 21.64 29 32448 442231 64024024
Asphyxia 133.06 21.64 74 32403 9492 64456763
Somnolence 132.84 21.64 307 32170 203338 64262917
Incorrect route of product administration 132.63 21.64 103 32374 23195 64443060
Rash 132.36 21.64 34 32443 458515 64007740
Off label use 131.76 21.64 78 32399 632728 63833527
Pneumonia 131.28 21.64 59 32418 559517 63906738
Poisoning 129.51 21.64 99 32378 21780 64444475
Intentional self-injury 128.75 21.64 111 32366 28933 64437322
Agitation 120.57 21.64 183 32294 88184 64378071
Intentional product use issue 118.29 21.64 189 32288 95175 64371080
Pyrexia 117.45 21.64 68 32409 558576 63907679
Anaemia 117.37 21.64 24 32453 378656 64087599
Drug use disorder 113.02 21.64 57 32420 5997 64460258
Mydriasis 110.29 21.64 78 32399 15234 64451021
Condition aggravated 101.11 21.64 31 32446 372395 64093860
Pain in extremity 96.42 21.64 18 32459 303067 64163188
Loss of consciousness 94.83 21.64 222 32255 148143 64318112
Nausea 94.44 21.64 157 32320 785643 63680612
Pruritus 92.31 21.64 22 32455 312378 64153877
Headache 92.06 21.64 79 32398 529388 63936867
Postmortem blood drug level abnormal 88.21 21.64 26 32451 621 64465634
Joint swelling 85.25 21.64 6 32471 215376 64250879
Alcoholism 84.46 21.64 39 32438 3378 64462877
Sopor 83.10 21.64 88 32389 29573 64436682
Suicidal ideation 82.64 21.64 132 32345 66410 64399845
Depressed level of consciousness 81.86 21.64 147 32330 81289 64384966
Back pain 79.24 21.64 15 32462 250156 64216099
Accidental death 78.22 21.64 38 32439 3687 64462568
Neutropenia 76.68 21.64 14 32463 239610 64226645
Miosis 76.25 21.64 59 32418 13207 64453048
Alcohol withdrawal syndrome 75.86 21.64 30 32447 1773 64464482
Drug interaction 74.02 21.64 369 32108 361714 64104541
Cough 73.66 21.64 30 32447 302118 64164137
Tachycardia 72.85 21.64 202 32275 149377 64316878
Peripheral swelling 71.91 21.64 10 32467 209143 64257112
Infusion related reaction 69.96 21.64 3 32474 164464 64301791
Drug intolerance 69.55 21.64 7 32470 187985 64278270
Urinary tract infection 68.99 21.64 16 32461 231580 64234675
Metabolic acidosis 68.65 21.64 126 32351 70832 64395423
Asthenia 68.27 21.64 69 32408 427975 64038280
Constipation 66.06 21.64 17 32460 229320 64236935
Drug withdrawal syndrome 62.58 21.64 78 32399 31213 64435042
Malaise 61.90 21.64 65 32412 396182 64070073
Infection 60.89 21.64 10 32467 184870 64281385
Febrile neutropenia 59.94 21.64 11 32466 187646 64278609
Hypersensitivity 59.65 21.64 13 32464 196439 64269816
Pulmonary oedema 59.52 21.64 126 32351 78548 64387707
Nasopharyngitis 59.49 21.64 13 32464 196060 64270195
Alopecia 59.17 21.64 7 32470 165683 64300572
Haemoglobin decreased 57.06 21.64 14 32463 195049 64271206
Sepsis 55.90 21.64 23 32454 230318 64235937
Homicide 54.98 21.64 21 32456 1130 64465125
Drug abuser 54.82 21.64 35 32442 5773 64460482
Drug hypersensitivity 54.17 21.64 26 32451 237789 64228466
Weight increased 53.92 21.64 20 32457 213328 64252927
Drug screen positive 52.78 21.64 34 32443 5695 64460560
Decreased appetite 52.50 21.64 39 32438 281250 64185005
Swelling 52.02 21.64 9 32468 160209 64306046
Shock 51.83 21.64 79 32398 38161 64428094
Weight decreased 51.57 21.64 41 32436 285698 64180557
Medication error 51.22 21.64 91 32386 49875 64416380
General physical health deterioration 50.27 21.64 20 32457 204405 64261850
Opiates positive 48.77 21.64 18 32459 880 64465375
Road traffic accident 48.16 21.64 68 32409 30677 64435578
Product dose omission issue 47.98 21.64 19 32458 194728 64271527
Product administration error 46.08 21.64 63 32414 27580 64438675
Sinusitis 45.65 21.64 9 32468 145919 64320336
Abdominal discomfort 44.56 21.64 18 32459 182304 64283951
Electrocardiogram QRS complex prolonged 44.37 21.64 37 32440 9207 64457048
Hepatic fibrosis 44.00 21.64 30 32447 5522 64460733
Urticaria 42.25 21.64 11 32466 147306 64318949
Liver injury 40.79 21.64 62 32415 29870 64436385
Pancytopenia 40.53 21.64 11 32466 143298 64322957
Amnesia 39.66 21.64 80 32397 48189 64418066
White blood cell count decreased 39.53 21.64 15 32462 157822 64308433
Blood ethanol increased 38.75 21.64 14 32463 644 64465611
Therapeutic product effect decreased 38.50 21.64 6 32471 115345 64350910
Musculoskeletal stiffness 37.70 21.64 8 32469 123198 64343057
Sinus tachycardia 37.42 21.64 62 32415 32126 64434129
Unresponsive to stimuli 37.28 21.64 80 32397 50313 64415942
Dizziness 37.24 21.64 103 32374 430060 64036195
Accidental overdose 36.84 21.64 63 32414 33494 64432761
Cerebrovascular accident 36.29 21.64 12 32465 137571 64328684
Electrocardiogram QT prolonged 35.43 21.64 104 32373 79344 64386911
Therapeutic product effect incomplete 35.42 21.64 5 32472 103477 64362778
Malignant neoplasm progression 35.21 21.64 7 32470 112864 64353391
Interstitial lung disease 35.20 21.64 4 32473 97728 64368527
Cardiac failure congestive 35.13 21.64 11 32466 130569 64335686
Blood ethanol 35.04 21.64 9 32468 126 64466129
Chemical submission 34.79 21.64 10 32467 218 64466037
Fall 34.46 21.64 102 32375 416724 64049531
Somnambulism 34.29 21.64 25 32452 5116 64461139
Amphetamines positive 34.24 21.64 10 32467 231 64466024
Asthma 34.04 21.64 4 32473 95221 64371034
Toxicologic test abnormal 33.49 21.64 15 32462 1210 64465045
Thrombocytopenia 33.47 21.64 38 32439 223763 64242492
Dehydration 33.30 21.64 36 32441 216727 64249528
Bezoar 33.27 21.64 18 32459 2185 64464070
Postmortem blood drug level 33.27 21.64 10 32467 256 64465999
Alcohol intolerance 33.26 21.64 11 32466 387 64465868
Abdominal pain 33.24 21.64 67 32410 312308 64153947
Victim of sexual abuse 33.02 21.64 11 32466 396 64465859
Euphoric mood 32.93 21.64 27 32450 6564 64459691
Abnormal behaviour 32.88 21.64 60 32417 33562 64432693
Myocardial fibrosis 32.82 21.64 16 32461 1564 64464691
Dysarthria 32.69 21.64 84 32393 59322 64406933
Withdrawal syndrome 32.49 21.64 49 32428 23443 64442812
Oedema peripheral 32.23 21.64 35 32442 210282 64255973
Muscular weakness 32.05 21.64 12 32465 127326 64338929
Brain oedema 31.90 21.64 47 32430 22028 64444227
Deep vein thrombosis 31.83 21.64 7 32470 105175 64361080
Platelet count decreased 31.59 21.64 23 32454 167688 64298567
Chest pain 31.20 21.64 44 32433 235936 64230319
Substance dependence 31.02 21.64 11 32466 479 64465776
Rhabdomyolysis 30.84 21.64 109 32368 91617 64374638
Pulmonary embolism 30.37 21.64 18 32459 146338 64319917
Leukopenia 30.11 21.64 7 32470 101235 64365020
Septic shock 29.98 21.64 8 32469 105429 64360826
Acute hepatic failure 29.96 21.64 50 32427 26062 64440193
Seizure 29.79 21.64 164 32313 166728 64299527
Bronchitis 29.54 21.64 9 32468 108734 64357521
Hypertrophic scar 29.03 21.64 5 32472 6 64466249
Respiratory acidosis 28.95 21.64 30 32447 9825 64456430
Injection site pain 28.89 21.64 10 32467 111398 64354857
Cellulitis 28.82 21.64 6 32471 93651 64372604
Erythema 28.80 21.64 31 32446 187039 64279216
Renal impairment 27.46 21.64 17 32460 135000 64331255
Impaired driving ability 27.40 21.64 21 32456 4633 64461622
Physical assault 27.23 21.64 14 32463 1532 64464723
Protein C increased 26.87 21.64 7 32470 104 64466151
Arthritis 26.56 21.64 5 32472 83809 64382446
Stomatitis 26.48 21.64 11 32466 109594 64356661
Substance use disorder 26.16 21.64 9 32468 358 64465897
Restlessness 25.88 21.64 60 32417 39725 64426530
Injection site erythema 25.24 21.64 3 32474 70797 64395458
Wheezing 25.13 21.64 5 32472 80574 64385681
Drug level increased 24.96 21.64 54 32423 34142 64432113
Hypotension 24.39 21.64 296 32181 380678 64085577
Abdominal distension 24.23 21.64 9 32468 95985 64370270
Myocardial infarction 23.87 21.64 29 32448 165792 64300463
Pulmonary congestion 23.83 21.64 43 32434 23837 64442418
Abdominal pain upper 23.76 21.64 32 32445 174998 64291257
Influenza 23.70 21.64 12 32465 106519 64359736
Neuropathy peripheral 23.62 21.64 15 32462 117510 64348745
Musculoskeletal pain 23.43 21.64 6 32471 81288 64384967
Discomfort 23.25 21.64 6 32471 80872 64385383
Induced abortion failed 23.11 21.64 7 32470 184 64466071
Chest discomfort 23.09 21.64 15 32462 116091 64350164
Acute kidney injury 22.70 21.64 133 32344 449107 64017148
Cardiac failure 22.61 21.64 20 32457 132353 64333902
Sensorimotor disorder 22.61 21.64 10 32467 783 64465472
Accidental poisoning 22.30 21.64 12 32465 1441 64464814
Lower respiratory tract infection 22.05 21.64 10 32467 94604 64371651
Productive cough 21.89 21.64 5 32472 73198 64393057
Substance-induced mood disorder 21.70 21.64 6 32471 113 64466142
Gastrointestinal disorder 21.67 21.64 9 32468 89700 64376555
Coma scale abnormal 21.65 21.64 23 32454 7751 64458504

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A01AB02 ALIMENTARY TRACT AND METABOLISM
STOMATOLOGICAL PREPARATIONS
STOMATOLOGICAL PREPARATIONS
Antiinfectives and antiseptics for local oral treatment
ATC D08AX01 DERMATOLOGICALS
ANTISEPTICS AND DISINFECTANTS
ANTISEPTICS AND DISINFECTANTS
Other antiseptics and disinfectants
ATC D11AX25 DERMATOLOGICALS
OTHER DERMATOLOGICAL PREPARATIONS
OTHER DERMATOLOGICAL PREPARATIONS
Other dermatologicals
ATC S02AA06 SENSORY ORGANS
OTOLOGICALS
ANTIINFECTIVES
Antiinfectives
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
MeSH PA D009676 Noxae
MeSH PA D016877 Oxidants
CHEBI has role CHEBI:23357 cofactor
CHEBI has role CHEBI:33281 antibiotics
CHEBI has role CHEBI:48219 disinfectants
CHEBI has role CHEBI:50902 genotoxic agent
CHEBI has role CHEBI:50910 agente neurotoxico
CHEBI has role CHEBI:59163 biological marker
CHEBI has role CHEBI:63248 oxidizer
CHEBI has role CHEBI:63490 explosive compounds
CHEBI has role CHEBI:65259 GABA antagonists
CHEBI has role CHEBI:68495 Type I cell-death inducers
CHEBI has role CHEBI:75771 Mus musculus metabolites
CHEBI has role CHEBI:75772 S. cerevisiae metabolites
CHEBI has role CHEBI:76967 human xenobiotic metabolites
CHEBI has role CHEBI:76971 Escherichia coli metabolites
CHEBI has role CHEBI:149552 emetics

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Antiseptic preparation indication 261276004




🐶 Veterinary Drug Use

SpeciesUseRelation
Fish Control mortality caused by saprolegniasis Indication
Fish Control mortality caused by bacterial gill disease associated with Flavobacterium branchiophilum Indication
Fish Control mortality caused by saprolegniasis Indication
Fish Control mortality caused by external columnaris disease associated with Flavobacterium columnare (Flexibacter columnaris) Indication
Fish Control mortality caused by external columnaris disease associated with Flavobacterium columnare (Flexibacter columnaris) Indication

🐶 Veterinary products

ProductApplicantIngredients
35% PEROX-AID Syndel USA 1

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.99 acidic
pKa2 12.0 acidic

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
40% ESKATA ACLARIS N209305 Dec. 14, 2017 DISCN SOLUTION TOPICAL 7381427 June 8, 2022 TREATMENT OF SEBORRHEIC KERATOSES THAT ARE RAISED
40% ESKATA ACLARIS N209305 Dec. 14, 2017 DISCN SOLUTION TOPICAL 10098910 April 21, 2035 TREATMENT OF SEBORRHEIC KERATOSES THAT ARE RAISED
40% ESKATA ACLARIS N209305 Dec. 14, 2017 DISCN SOLUTION TOPICAL 9980983 April 21, 2035 TREATMENT OF SEBORRHEIC KERATOSES THAT ARE RAISED
40% ESKATA ACLARIS N209305 Dec. 14, 2017 DISCN SOLUTION TOPICAL 9675639 July 4, 2035 TREATMENT OF SEBORRHEIC KERATOSES THAT ARE RAISED

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
BBX060AN9V UNII
D00008 KEGG_DRUG
4019590 VANDF
C0020281 UMLSCUI
CHEBI:16240 CHEBI
PEO PDB_CHEM_ID
CHEMBL71595 ChEMBL_ID
784 PUBCHEM_CID
DB11091 DRUGBANK_ID
D006861 MESH_DESCRIPTOR_UI
372426 RXNORM
35389 MMSL
35390 MMSL
4847 MMSL
5359 MMSL
003157 NDDF
31231007 SNOMEDCT_US
387171003 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
PEROXYL MOUTH SORE MILD MINT HUMAN OTC DRUG LABEL 1 0126-0083 RINSE 15 mg BUCCAL OTC MONOGRAPH NOT FINAL 13 sections
PEROXYL MOUTH SORE MILD MINT HUMAN OTC DRUG LABEL 1 0126-0083 RINSE 15 mg BUCCAL OTC MONOGRAPH NOT FINAL 13 sections
Sore Mouth Cleanser HUMAN OTC DRUG LABEL 1 0363-0085 MOUTHWASH 1588 mg TOPICAL OTC monograph not final 10 sections
Hydrogen Peroxide3 Percent HUMAN OTC DRUG LABEL 1 0363-0267 LIQUID 2.65 mL TOPICAL OTC MONOGRAPH NOT FINAL 13 sections
Hydrogen Peroxide3 Percent HUMAN OTC DRUG LABEL 1 0363-0268 LIQUID 2.65 mL TOPICAL OTC monograph not final 13 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0363-0871 SOLUTION 30 mg TOPICAL OTC monograph not final 12 sections
Oral Sore Antiseptic HUMAN OTC DRUG LABEL 2 0363-1045 LIQUID 1.50 mg ORAL OTC monograph not final 13 sections
Humco Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0395-1113 LIQUID 30 mg TOPICAL OTC monograph not final 12 sections
Humco Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0395-1113 LIQUID 30 mg TOPICAL OTC monograph not final 12 sections
Humco Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0395-9116 LIQUID 30 mg TOPICAL OTC monograph not final 12 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0404-0001 SOLUTION 30 mg TOPICAL OTC MONOGRAPH NOT FINAL 14 sections
Henry Schein Mouth HUMAN OTC DRUG LABEL 1 0404-0012 RINSE 1.50 mL ORAL OTC monograph not final 12 sections
Sore Mouth Cleanser HUMAN OTC DRUG LABEL 1 0869-0462 MOUTHWASH 1588 mg TOPICAL OTC monograph not final 12 sections
Sore Mouth Cleanser HUMAN OTC DRUG LABEL 1 0869-0462 MOUTHWASH 1588 mg TOPICAL OTC monograph not final 12 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0869-0871 SOLUTION 30 mg TOPICAL OTC monograph not final 12 sections
First Aid Only Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 0924-0171 SPRAY 30 mL TOPICAL OTC monograph not final 11 sections
Hydrogen Peroxide Antiseptic HUMAN OTC DRUG LABEL 1 0924-0932 SPRAY 30 mL TOPICAL OTC monograph not final 11 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 10202-001 SOLUTION 30 mg TOPICAL OTC MONOGRAPH NOT FINAL 13 sections
Orajel Alcohol Free Antiseptic RinseFor All Mouth Sores HUMAN OTC DRUG LABEL 2 10237-759 LIQUID 1.50 mL ORAL OTC monograph not final 11 sections
Orajel Antiseptic Rinse For All Mouth Sores HUMAN OTC DRUG LABEL 2 10237-760 LIQUID 15 mg ORAL OTC monograph not final 12 sections
Orajel Antiseptic Alcohol-Free Mouth Sore Rinse HUMAN OTC DRUG LABEL 2 10237-784 LIQUID 15 mg ORAL OTC monograph not final 11 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 10565-001 SOLUTION 3 mL TOPICAL OTC monograph not final 14 sections
HYDROGEN PEROXIDE HUMAN OTC DRUG LABEL 1 10733-800 SOLUTION 2.65 mL TOPICAL OTC monograph not final 9 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 11344-002 SOLUTION 30 mg TOPICAL OTC monograph not final 13 sections
Hydrogen Peroxide3 Percent HUMAN OTC DRUG LABEL 1 11673-268 LIQUID 2.65 mL TOPICAL OTC MONOGRAPH NOT FINAL 13 sections
Up and Up 3 Hydrogen Peroxide Wipes HUMAN OTC DRUG LABEL 1 11673-327 CLOTH 30 mg TOPICAL OTC monograph not final 13 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 11673-871 SOLUTION 30 mg TOPICAL OTC monograph not final 11 sections
Hydrogen Peroxide HUMAN OTC DRUG LABEL 1 11822-0871 SOLUTION 0.30 kg TOPICAL OTC monograph not final 13 sections
Sore Mouth Cleanser HUMAN OTC DRUG LABEL 1 11822-1462 MOUTHWASH 1588 mg TOPICAL OTC monograph not final 12 sections
Sore Mouth Cleanser HUMAN OTC DRUG LABEL 1 11822-1462 MOUTHWASH 1588 mg TOPICAL OTC monograph not final 12 sections