homosalate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 3279 | 118-56-9 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
cpd not photoallergenic
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Macular degeneration | 504.14 | 21.44 | 114 | 1722 | 14274 | 50589014 |
| Drug ineffective | 95.92 | 21.44 | 131 | 1705 | 819202 | 49784086 |
| Chronic sinusitis | 28.28 | 21.44 | 10 | 1826 | 6135 | 50597153 |
| Paraesthesia oral | 28.06 | 21.44 | 12 | 1824 | 12209 | 50591079 |
| Jarisch-Herxheimer reaction | 25.75 | 21.44 | 5 | 1831 | 290 | 50602998 |
| Dermatophytosis | 22.15 | 21.44 | 4 | 1832 | 156 | 50603132 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Macular degeneration | 31.69 | 18.15 | 11 | 2612 | 5699 | 64490410 |
| Pyrexia | 25.33 | 18.15 | 64 | 2559 | 558580 | 63937529 |
| Chronic sinusitis | 23.31 | 18.15 | 9 | 2614 | 6283 | 64489826 |
| Paraesthesia oral | 22.83 | 18.15 | 11 | 2612 | 13120 | 64482989 |
| Jarisch-Herxheimer reaction | 20.97 | 18.15 | 5 | 2618 | 682 | 64495427 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D003358 | Cosmetics |
| MeSH PA | D003879 | Dermatologic Agents |
| MeSH PA | D020011 | Protective Agents |
| MeSH PA | D011837 | Radiation-Protective Agents |
| MeSH PA | D013473 | Sunscreening Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.91 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4021147 | VUID |
| N0000179485 | NUI |
| D04450 | KEGG_DRUG |
| 4021147 | VANDF |
| C0304631 | UMLSCUI |
| CHEBI:91642 | CHEBI |
| CHEMBL1377575 | ChEMBL_ID |
| DB11064 | DRUGBANK_ID |
| C060446 | MESH_SUPPLEMENTAL_RECORD_UI |
| 8362 | PUBCHEM_CID |
| 3183 | INN_ID |
| V06SV4M95S | UNII |
| 91326 | RXNORM |
| 001969 | NDDF |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| TOTAL DEFENSE REPAIR BROAD SPECTRUM SPF 50 Sunscreen | HUMAN OTC DRUG LABEL | 4 | 0023-5501 | LOTION | 60 mg | TOPICAL | OTC monograph not final | 8 sections |
| Solbar Thirty SPF 30 | HUMAN OTC DRUG LABEL | 5 | 0096-0685 | CREAM | 0.12 g | TOPICAL | OTC monograph final | 8 sections |
| Solbar Avo SPF35 | HUMAN OTC DRUG LABEL | 4 | 0096-0687 | CREAM | 0.08 g | TOPICAL | OTC monograph final | 8 sections |
| Solbar Zinc SPF38 | HUMAN OTC DRUG LABEL | 3 | 0096-0688 | CREAM | 0.10 1 | TOPICAL | OTC monograph final | 8 sections |
| Daily Facial MoisturizerSPF 25 | HUMAN OTC DRUG LABEL | 4 | 0096-0721 | CREAM | 0.06 g | TOPICAL | OTC monograph final | 11 sections |
| Cetaphil Daily Facial Moisturizer with suncreen SPF 35 | HUMAN OTC DRUG LABEL | 4 | 0299-4113 | LOTION | 95 mg | TOPICAL | OTC monograph final | 12 sections |
| Cetaphil Healthy Radiance Whipped Day Cream Broad Spectrum SPF 30 | HUMAN OTC DRUG LABEL | 4 | 0299-4118 | LOTION | 125 mg | TOPICAL | OTC monograph final | 12 sections |
| Cetaphil Healthy Radiance Whipped Day Cream Broad Spectrum SPF 30 | HUMAN OTC DRUG LABEL | 4 | 0299-4118 | LOTION | 125 mg | TOPICAL | OTC monograph final | 12 sections |
| Almay Anti Aging Lip Care SPF 20 | HUMAN OTC DRUG LABEL | 5 | 0311-0709 | LIPSTICK | 5 mg | TOPICAL | OTC monograph final | 8 sections |
| Almay Best Blend Forever Makeup | HUMAN OTC DRUG LABEL | 4 | 0311-0719 | LOTION | 3.50 mg | TOPICAL | OTC monograph final | 5 sections |
| Almay Healthy Biome Makeup | HUMAN OTC DRUG LABEL | 5 | 0311-0723 | EMULSION | 5 mg | TOPICAL | OTC monograph final | 7 sections |
| Hydrating Antioxidant Moiturizer | HUMAN OTC DRUG LABEL | 4 | 0363-0540 | CREAM | 4.72 g | TOPICAL | OTC monograph not final | 11 sections |
| WALGREEN SPORT SPF 70 SUNSCREEN | HUMAN OTC DRUG LABEL | 5 | 0363-0900 | LOTION | 100 mg | TOPICAL | OTC monograph not final | 12 sections |
| WALGREENS SPORT SPF 50 SUNSCREEN | HUMAN OTC DRUG LABEL | 4 | 0363-0924 | AEROSOL, SPRAY | 100 mg | TOPICAL | OTC monograph not final | 13 sections |
| WALGREENS BROAD SPECTRUM SPF 110 AGE PROTECTION SUNSCREEN | HUMAN OTC DRUG LABEL | 5 | 0363-0933 | LOTION | 150 mg | TOPICAL | OTC monograph not final | 12 sections |
| WALGREENS BROAD SPECTRUM SPF 70 SUNSCREEN | HUMAN OTC DRUG LABEL | 5 | 0363-0936 | STICK | 150 mg | TOPICAL | OTC monograph not final | 11 sections |
| WALGREENS SPORT BROAD SPECTRUM SPF 50 FACES SUNSCREEN | HUMAN OTC DRUG LABEL | 5 | 0363-0937 | LOTION | 130 mg | TOPICAL | OTC monograph not final | 13 sections |
| WALGREENS BROAD SPECTRUM SPF 30 DRY TOUCH SUNSCREEN | HUMAN OTC DRUG LABEL | 5 | 0363-0940 | LOTION | 70 mg | TOPICAL | OTC monograph not final | 13 sections |
| WALGREENS BROAD SPECTRUM SPORT SPF 50 SUNSCREEN | HUMAN OTC DRUG LABEL | 4 | 0363-0943 | LOTION | 100 mg | TOPICAL | OTC monograph not final | 12 sections |
| Walgreens Sport SPF 50 | HUMAN OTC DRUG LABEL | 5 | 0363-0956 | SPRAY | 100 mg | TOPICAL | OTC monograph not final | 12 sections |
| Walgreens SPF55 Sunscreen | HUMAN OTC DRUG LABEL | 4 | 0363-0961 | STICK | 150 mg | TOPICAL | OTC monograph not final | 12 sections |
| Walgreens SPF 55 Dry Touch | HUMAN OTC DRUG LABEL | 5 | 0363-0963 | LOTION | 100 mg | TOPICAL | OTC monograph not final | 12 sections |
| Walgreens Dry Touch Broad Spectrum SPF 55 | HUMAN OTC DRUG LABEL | 4 | 0363-0965 | LOTION | 100 mg | TOPICAL | OTC monograph not final | 11 sections |
| Walgreens SPF 30 Hydrating Continuous | HUMAN OTC DRUG LABEL | 3 | 0363-0970 | AEROSOL, SPRAY | 70 mg | TOPICAL | OTC monograph not final | 11 sections |
| Walgreens SPF55 Sunscreen Reef-Conscious Formula | HUMAN OTC DRUG LABEL | 4 | 0363-0976 | STICK | 150 mg | TOPICAL | OTC monograph not final | 12 sections |
| Walgreens SPF 50 Clear Complexion For Face | HUMAN OTC DRUG LABEL | 5 | 0363-0981 | LOTION | 40 mg | TOPICAL | OTC monograph not final | 11 sections |
| Walgreens Sport SPF 30 | HUMAN OTC DRUG LABEL | 5 | 0363-0991 | SPRAY | 100 mg | TOPICAL | OTC monograph not final | 13 sections |
| Well at Walgreens Kids Sunscreen Broad Spectrum SPF 50 | HUMAN OTC DRUG LABEL | 5 | 0363-0992 | SPRAY | 100 mg | TOPICAL | OTC monograph not final | 12 sections |
| Well at Walgreens Mist Sheer Broad Spectrum Broad Spectrum SPF 30 | HUMAN OTC DRUG LABEL | 5 | 0363-0996 | SPRAY | 800 mg | TOPICAL | OTC monograph not final | 13 sections |
| Hydrating SPF 50 | HUMAN OTC DRUG LABEL | 4 | 0363-1120 | SPRAY | 15 g | TOPICAL | OTC monograph not final | 7 sections |