hexetidine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
histamine-H2-receptor antagonists, cimetidine derivatives 3277 141-94-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hexetidine
  • glypesin
  • hexoral
A bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
  • Molecular weight: 339.61
  • Formula: C21H45N3
  • CLOGP: 8.14
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 1
  • TPSA: 32.50
  • ALOGS: -4.76
  • ROTB: 12

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A01AB12 ALIMENTARY TRACT AND METABOLISM
STOMATOLOGICAL PREPARATIONS
STOMATOLOGICAL PREPARATIONS
Antiinfectives and antiseptics for local oral treatment
ATC G01AX16 GENITO URINARY SYSTEM AND SEX HORMONES
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Other antiinfectives and antiseptics
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
MeSH PA D000935 Antifungal Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.52 Basic
pKa2 6.52 Basic
pKa3 5.17 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000167195 NUI
D07068 KEGG_DRUG
C0019468 UMLSCUI
CHEBI:94339 CHEBI
CHEMBL144673 ChEMBL_ID
DB08958 DRUGBANK_ID
D006590 MESH_DESCRIPTOR_UI
3607 PUBCHEM_CID
522 INN_ID
852A84Y8LS UNII
5301 RXNORM
18447 MMSL
003906 NDDF
2497003 SNOMEDCT_US
387132001 SNOMEDCT_US

Pharmaceutical products:

None