guamecycline 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, protein-synthesis inhibitors, tetracycline derivatives 3273 16545-11-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • guamecycline
  • tetrabiguanide
  • Xanthomycin A
  • xantomicina
  • Molecular weight: 626.67
  • Formula: C29H38N8O8
  • CLOGP: -3.64
  • LIPINSKI: 3
  • HAC: 16
  • HDO: 10
  • TPSA: 259.86
  • ALOGS: -3.35
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.72 acidic
pKa2 7.83 acidic
pKa3 9.76 acidic
pKa4 11.9 acidic
pKa5 13.21 acidic
pKa6 13.73 acidic
pKa7 12.58 Basic
pKa8 9.07 Basic
pKa9 7.12 Basic
pKa10 2.37 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0061935 UMLSCUI
CHEBI:135854 CHEBI
CHEMBL2008915 ChEMBL_ID
C001312 MESH_SUPPLEMENTAL_RECORD_UI
2705 INN_ID
4NQR4R6G3S UNII
54688683 PUBCHEM_CID

Pharmaceutical products:

None