furtrethonium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
quaternary ammonium compounds	3256	7618-86-2

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

furtrethonium chloride
furmethide
furtrethonium
furfuryltrimethylammonium
furtretonium
furtrimethonium
furtrethonium iodide

Molecular weight: 140.21
Formula: C8H14NO
CLOGP: -3.26
LIPINSKI: 0
HAC: 2
HDO: 0
TPSA: 13.14
ALOGS: -3.65
ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D018678	Cholinergic Agents
MeSH PA	D018679	Cholinergic Agonists
MeSH PA	D018377	Neurotransmitter Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Muscarinic acetylcholine receptor M1	GPCR	P11229	ACM1_HUMAN	AGONIST	Ki	4.10		IUPHAR
Muscarinic acetylcholine receptor M2	GPCR	P08172	ACM2_HUMAN	AGONIST	Ki	4.50		IUPHAR
Muscarinic acetylcholine receptor M3	GPCR	P20309	ACM3_HUMAN	AGONIST	Ki	4.10		IUPHAR
Muscarinic acetylcholine receptor M4	GPCR	P08173	ACM4_HUMAN	AGONIST	Ki	4.30		IUPHAR

External reference:

ID	Source
6035-90-1	SECONDARY_CAS_RN
541-64-0	SECONDARY_CAS_RN
C0060876	UMLSCUI
CHEBI:134764	CHEBI
CHEMBL2110739	ChEMBL_ID
10938	PUBCHEM_CID
C028530	MESH_SUPPLEMENTAL_RECORD_UI
299	IUPHAR_LIGAND_ID
AIQ630U6XO	UNII
CHEMBL2105806	ChEMBL_ID
133	INN_ID

Pharmaceutical products:

None