enviomycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, produced by Streptomyces strains 3180 33103-22-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • enviomycin
  • Tuberactinomycin N
  • enviomycin sulfate
Cyclic basic peptide related to VIOMYCIN. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin.
  • Molecular weight: 685.70
  • Formula: C25H43N13O10
  • CLOGP: -6.40
  • LIPINSKI: 3
  • HAC: 23
  • HDO: 15
  • TPSA: 392.86
  • ALOGS: -2.43
  • ROTB: 10

Drug dosage:

DoseUnitRoute
1 g P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J04AB06 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIMYCOBACTERIALS
DRUGS FOR TREATMENT OF TUBERCULOSIS
Antibiotics
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000904 Antibiotics, Antitubercular
MeSH PA D000995 Antitubercular Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Pulmonary tuberculosis indication 154283005 DOID:2957




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.82 acidic
pKa2 12.11 acidic
pKa3 12.74 acidic
pKa4 13.0 acidic
pKa5 13.35 acidic
pKa6 13.69 acidic
pKa7 13.92 acidic
pKa8 10.34 Basic
pKa9 9.82 Basic
pKa10 6.91 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D03278 KEGG_DRUG
C0014405 UMLSCUI
CHEBI:135872 CHEBI
CHEMBL2146142 ChEMBL_ID
D004776 MESH_DESCRIPTOR_UI
DB08993 DRUGBANK_ID
3577 INN_ID
53760-33-1 SECONDARY_CAS_RN
XU299C23A2 UNII
010912 NDDF
010913 NDDF
3032903 PUBCHEM_CID

Pharmaceutical products:

None