diosmin Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3157 520-27-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • diosmin
  • barosmin
  • diosmil
  • diosmine
  • flebosten
  • flebosmil
A bioflavonoid that strengthens vascular walls.
  • Molecular weight: 608.55
  • Formula: C28H32O15
  • CLOGP: 0.23
  • LIPINSKI: 3
  • HAC: 15
  • HDO: 8
  • TPSA: 234.29
  • ALOGS: -2.60
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC C05CA03 CARDIOVASCULAR SYSTEM
VASOPROTECTIVES
CAPILLARY STABILIZING AGENTS
Bioflavonoids
ATC C05CA53 CARDIOVASCULAR SYSTEM
VASOPROTECTIVES
CAPILLARY STABILIZING AGENTS
Bioflavonoids
CHEBI has role CHEBI:67079 anti-inflammatory agent

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.73 acidic
pKa2 10.43 acidic
pKa3 12.32 acidic
pKa4 13.05 acidic
pKa5 13.7 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D004145 MESH_DESCRIPTOR_UI
N0000167025 NUI
C0012498 UMLSCUI
D07858 KEGG_DRUG
126142004 SNOMEDCT_US
3489 RXNORM
8143001 SNOMEDCT_US
005803 NDDF
4036523 VANDF
7QM776WJ5N UNII
4370 INN_ID
CHEMBL231884 ChEMBL_ID
DB08995 DRUGBANK_ID
CHEBI:4631 CHEBI
5281613 PUBCHEM_CID

Pharmaceutical products:

None