All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

dimethicone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	3152	9006-65-9

Description:

Molecule	Description
Synonyms: simethicone dimethicone Silicone Fluid 350 polydimethylsiloxane dimeticone dimethicone 410	A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base. Molecular weight: Formula: C6H18Si2(C2H6O2Si)n CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: ALOGS: ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
June 26, 1997	FDA	MCNEIL

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Completed suicide	1904.69	9.33	1991	138711	131842	56019523
Toxicity to various agents	861.96	9.33	1798	138904	222766	55928599
Drug abuse	569.54	9.33	771	139931	66839	56084526
Cardio-respiratory arrest	367.80	9.33	564	140138	54757	56096608
Milk-alkali syndrome	310.70	9.33	101	140601	597	56150768
Intentional overdose	299.32	9.33	578	140124	67539	56083826
Alcohol interaction	273.25	9.33	128	140574	2205	56149160
Drug ineffective	234.33	9.33	1347	139355	917642	55233723
Diarrhoea	219.59	9.33	2497	138205	636010	55515355
Overdose	188.72	9.33	638	140064	105192	56046173
Suspected suicide	181.11	9.33	132	140570	5334	56146031
Suicide attempt	176	9.33	423	140279	57413	56093952
Liver injury	166.77	9.33	341	140361	41507	56109858
Macular degeneration	164.18	9.33	219	140483	18689	56132676
Rheumatoid arthritis	160.54	9.33	460	140242	382144	55769221
Hypocalcaemia	156.69	9.33	268	140434	28492	56122873
Coma	150.03	9.33	406	140296	59249	56092116
Pneumonia aspiration	130.19	9.33	265	140437	32146	56119219
Alcohol poisoning	125.38	9.33	70	140632	1765	56149600
Alcohol abuse	102.11	9.33	63	140639	1921	56149444
Alcohol use	100.93	9.33	63	140639	1962	56149403
Recalled product	100.47	9.33	55	140647	1333	56150032
Hepatotoxicity	90.63	9.33	224	140478	30929	56120436
Somnolence	90.22	9.33	708	139994	162705	55988660
Gastrooesophageal reflux disease	89.63	9.33	429	140273	82828	56068537
Respiratory arrest	81.59	9.33	213	140489	30412	56120953
Hypomania	80.50	9.33	79	140623	4823	56146542
Drug hypersensitivity	75.19	9.33	393	140309	274812	55876553
Jaundice cholestatic	72.68	9.33	79	140623	5440	56145925
Abdominal pain	71.05	9.33	972	139730	257833	55893532
Asphyxia	69.58	9.33	79	140623	5710	56145655
Therapeutic product effect decreased	67.09	9.33	209	140493	169243	55982122
Rash	66.78	9.33	851	139851	492196	55659169
Dehydration	66.24	9.33	647	140055	158178	55993187
Off label use	66.04	9.33	986	139716	555194	55596171
Hypercalcaemia	65.92	9.33	175	140527	25236	56126129
Nephrocalcinosis	64.70	9.33	37	140665	978	56150387
Product dose omission issue	63.10	9.33	280	140422	204473	55946892
Sleep disorder due to general medical condition, insomnia type	61.75	9.33	16	140686	43322	56108043
Gastrointestinal toxicity	59.20	9.33	75	140627	6081	56145284
Methaemoglobinaemia	57.92	9.33	46	140656	2116	56149249
Calcium ionised decreased	56.20	9.33	23	140679	281	56151084
Infusion related reaction	55.55	9.33	301	140401	208630	55942735
Device expulsion	54.88	9.33	6	140696	30443	56120922
Synovitis	53.13	9.33	215	140487	161090	55990275
Intentional product misuse	51.56	9.33	260	140442	51244	56100121
Schizophrenia	50.92	9.33	93	140609	10406	56140959
Ill-defined disorder	50.55	9.33	58	140644	68485	56082880
Hypersensitivity	50.21	9.33	405	140297	256003	55895362
Tetany	49.67	9.33	38	140664	1654	56149711
Segmental diverticular colitis	49.45	9.33	18	140684	156	56151209
Pain	49.07	9.33	1273	139429	661911	55489454
Neurologic neglect syndrome	48.93	9.33	42	140660	2156	56149209
Drug intolerance	48.82	9.33	425	140277	264393	55886972
Pedal pulse abnormal	48.66	9.33	18	140684	164	56151201
Lower respiratory tract infection	47.99	9.33	138	140564	114656	56036709
Pruritus	47.16	9.33	535	140167	316088	55835277
Maternal exposure during pregnancy	46.65	9.33	280	140422	189273	55962092
Vaginal flatulence	46.16	9.33	26	140676	667	56150698
Flatulence	45.82	9.33	177	140525	31111	56120254
Nicotine dependence	45.64	9.33	26	140676	682	56150683
Exposure to toxic agent	45.58	9.33	51	140651	3627	56147738
Infection	45.04	9.33	304	140398	199902	55951463
Pulmonary toxicity	44.97	9.33	75	140627	7808	56143557
Sinusitis	44.45	9.33	300	140402	197281	55954084
Carotid artery thrombosis	44.19	9.33	40	140662	2204	56149161
Contraindicated product administered	43.85	9.33	279	140423	186007	55965358
Joint swelling	43.42	9.33	489	140213	289311	55862054
Postmortem blood drug level abnormal	42.98	9.33	20	140682	339	56151026
Injection site reaction	42.68	9.33	42	140660	53205	56098160
Full blood count abnormal	42.32	9.33	154	140548	26308	56125057
Hypophosphataemic osteomalacia	42.30	9.33	16	140686	156	56151209
Injection site erythema	42.06	9.33	81	140621	77367	56073998
Constipation	41.72	9.33	723	139979	201220	55950145
Blood alcohol increased	41.44	9.33	23	140679	573	56150792
Blood calcium decreased	41.17	9.33	142	140560	23627	56127738
Facet joint syndrome	41.15	9.33	66	140636	6651	56144714
Headache	41.06	9.33	1074	139628	557970	55593395
Nasal obstruction	40.96	9.33	30	140672	1221	56150144
Swelling	39.37	9.33	396	140306	239375	55911990
Small intestinal obstruction	38.81	9.33	111	140591	16714	56134651
Peripheral venous disease	38.80	9.33	81	140621	9998	56141367
Feeding intolerance	38.52	9.33	22	140680	580	56150785
Lip dry	38.35	9.33	79	140623	9661	56141704
Treatment failure	37.19	9.33	261	140441	170131	55981234
Cardiac arrest	36.13	9.33	352	140350	85962	56065403
Alcoholism	35.16	9.33	35	140667	2174	56149191
Vomiting	34.67	9.33	1549	139153	496679	55654686
Injection site pain	33.77	9.33	164	140538	116954	56034411
Throat clearing	33.58	9.33	29	140673	1501	56149864
Gastrointestinal disorder	33.56	9.33	156	140546	112546	56038819
Injection site swelling	33.09	9.33	36	140666	43542	56107823
Hand deformity	32.90	9.33	199	140503	134293	56017072
Sputum purulent	32.87	9.33	24	140678	972	56150393
Arteriosclerosis coronary artery	32.75	9.33	65	140637	7740	56143625
Weight increased	32.29	9.33	393	140309	229310	55922055
Salivary gland calculus	32.05	9.33	13	140689	155	56151210
Injection site pruritus	31.44	9.33	35	140667	41896	56109469
Systemic lupus erythematosus	31.41	9.33	293	140409	179785	55971580
Pemphigus	30.88	9.33	248	140454	156964	55994401
Anti-cyclic citrullinated peptide antibody positive	30.85	9.33	134	140568	98466	56052899
Skin haemorrhage	30.53	9.33	66	140636	8347	56143018
Discomfort	30.51	9.33	218	140484	141543	56009822
Product quality issue	30.43	9.33	21	140681	31715	56119650
Victim of sexual abuse	30.43	9.33	19	140683	592	56150773
Abdominal distension	30.28	9.33	312	140390	77314	56074051
Large intestine polyp	30.19	9.33	62	140640	7565	56143800
No adverse event	29.95	9.33	28	140674	36346	56115019
Substance abuse	29.85	9.33	46	140656	4479	56146886
Personality disorder	29.22	9.33	49	140653	5124	56146241
Alopecia	29.19	9.33	537	140165	292921	55858444
Head banging	28.78	9.33	16	140686	400	56150965
Hypokalaemia	28.47	9.33	361	140341	94076	56057289
Loss of personal independence in daily activities	28.34	9.33	106	140596	81263	56070102
Injection site bruising	27.96	9.33	33	140669	38488	56112877
Proctitis	27.54	9.33	33	140669	2527	56148838
Colitis	27.51	9.33	189	140513	41622	56109743
Frequent bowel movements	27.47	9.33	97	140605	16327	56135038
Arteriovenous fistula occlusion	27.38	9.33	15	140687	364	56151001
Eating disorder	26.89	9.33	99	140603	17006	56134359
Adjustment disorder	26.74	9.33	31	140671	2292	56149073
Rheumatoid nodule	26.59	9.33	3	140699	14854	56136511
Dyspnoea	26.55	9.33	1211	139491	591366	55559999
Product use in unapproved indication	26.36	9.33	225	140477	140597	56010768
Secondary immunodeficiency	26.20	9.33	23	140679	1217	56150148
Multiple sclerosis relapse	26.12	9.33	45	140657	44858	56106507
Wrong technique in product usage process	25.74	9.33	68	140634	58100	56093265
Herpes zoster	25.69	9.33	100	140602	75789	56075576
Stress fracture	25.69	9.33	56	140646	7121	56144244
Rib deformity	25.49	9.33	12	140690	209	56151156
Calciphylaxis	25.49	9.33	33	140669	2734	56148631
Hypercalciuria	25.42	9.33	13	140689	273	56151092
Haemorrhoids	25.37	9.33	109	140593	20097	56131268
Intestinal obstruction	25.09	9.33	137	140565	27834	56123531
Hypoparathyroidism	24.78	9.33	17	140685	623	56150742
Arthralgia	24.57	9.33	1015	139687	500654	55650711
Crohn's disease	23.99	9.33	51	140651	6376	56144989
Blood bilirubin increased	23.89	9.33	154	140548	33200	56118165
Myelosuppression	23.83	9.33	7	140695	17448	56133917
Blue toe syndrome	23.73	9.33	14	140688	393	56150972
Peripheral swelling	23.49	9.33	429	140273	234297	55917068
Cholelithiasis	23.42	9.33	174	140528	39290	56112075
Urticaria	23.28	9.33	240	140462	144436	56006929
Shunt stenosis	23.17	9.33	15	140687	498	56150867
Therapy cessation	22.43	9.33	21	140681	27243	56124122
Post procedural diarrhoea	22.34	9.33	14	140688	439	56150926
Gastrointestinal sounds abnormal	21.43	9.33	36	140666	3769	56147596
Multiple drug therapy	20.73	9.33	30	140672	2762	56148603
Coordination abnormal	20.65	9.33	74	140628	12547	56138818
Drug resistance	20.49	9.33	13	140689	20529	56130836
Sneezing	20.36	9.33	85	140617	15475	56135890
Psoriatic arthropathy	20.26	9.33	278	140424	73730	56077635
Psychotic disorder	20.21	9.33	114	140588	23444	56127921
Psoriasis	20.20	9.33	142	140560	92550	56058815
Migraine	19.89	9.33	131	140571	86666	56064699
Muscle injury	19.88	9.33	66	140636	52434	56098931
Sinus congestion	19.88	9.33	85	140617	15639	56135726
Glossodynia	19.86	9.33	265	140437	152193	55999172
Chemical submission	19.77	9.33	10	140692	205	56151160
Lymph node palpable	19.60	9.33	8	140694	97	56151268
Folliculitis	19.55	9.33	71	140631	54908	56096457
Poisoning deliberate	19.50	9.33	62	140640	9891	56141474
Musculoskeletal disorder	19.26	9.33	12	140690	19135	56132230
Abdominal rigidity	19.18	9.33	23	140679	1762	56149603
Drug eruption	18.77	9.33	22	140680	25741	56125624
Protein C increased	18.63	9.33	8	140694	111	56151254
Urine calcium/creatinine ratio increased	18.57	9.33	8	140694	112	56151253
Therapy interrupted	18.55	9.33	22	140680	25603	56125762
Rhinorrhoea	18.47	9.33	221	140481	56816	56094549
Red blood cell sedimentation rate increased	18.43	9.33	40	140662	36583	56114782
Gonorrhoea	18.26	9.33	8	140694	117	56151248
Renal tubular necrosis	18.15	9.33	64	140638	10764	56140601
Fanconi syndrome	18.01	9.33	19	140683	1264	56150101
Depressed level of consciousness	17.98	9.33	218	140484	56215	56095150
Respiratory tract congestion	17.98	9.33	82	140620	15509	56135856
Chronic kidney disease-mineral and bone disorder	17.95	9.33	10	140692	251	56151114
Injection site rash	17.95	9.33	10	140692	16948	56134417
Wheezing	17.84	9.33	275	140427	74751	56076614
Radiculopathy	17.83	9.33	42	140660	5623	56145742
Pericarditis	17.80	9.33	180	140522	108743	56042622
Oedema peripheral	17.78	9.33	557	140145	170697	55980668
Acquired haemophilia	17.75	9.33	17	140685	1007	56150358
Hypophosphataemia	17.71	9.33	59	140643	9643	56141722
Pregnancy	17.54	9.33	35	140667	32998	56118367
Angioedema	17.19	9.33	50	140652	41403	56109962
Myocarditis	17.19	9.33	55	140647	8803	56142562
Peripheral pulse decreased	17.12	9.33	6	140696	46	56151319
Hemiplegia	17.06	9.33	53	140649	8351	56143014
Premature delivery	16.79	9.33	26	140676	27034	56124331
Anaphylactic reaction	16.77	9.33	83	140619	58912	56092453
Myocardial infarction	16.65	9.33	150	140552	92720	56058645
Hip fracture	16.62	9.33	120	140582	26853	56124512
Impaired healing	16.58	9.33	138	140564	86703	56064662
Heavy menstrual bleeding	16.53	9.33	10	140692	16199	56135166
Pathological fracture	16.41	9.33	51	140651	8038	56143327
Drug use disorder	16.23	9.33	36	140666	4633	56146732
Metamyelocyte count increased	16.19	9.33	9	140693	225	56151140
Hepatocellular injury	15.95	9.33	26	140676	26488	56124877
Pneumothorax spontaneous	15.86	9.33	14	140688	746	56150619
Gluten sensitivity	15.85	9.33	12	140690	514	56150851
Red blood cell sedimentation rate abnormal	15.82	9.33	14	140688	18659	56132706
Hospitalisation	15.80	9.33	116	140586	74884	56076481
Wound	15.72	9.33	248	140454	138556	56012809
Affect lability	15.41	9.33	58	140644	10067	56141298
Blood potassium decreased	15.34	9.33	156	140546	38516	56112849
Abortion spontaneous	15.23	9.33	57	140645	43696	56107669
Coronary artery disease	15.20	9.33	34	140668	30762	56120603
Gastric dilatation	15.14	9.33	14	140688	793	56150572
Skin necrosis	15.07	9.33	6	140696	12355	56139010
Female genital tract fistula	14.90	9.33	34	140668	4458	56146907
Decreased appetite	14.83	9.33	680	140022	218551	55932814
Skin exfoliation	14.71	9.33	149	140553	36751	56114614
Therapeutic reaction time decreased	14.65	9.33	20	140682	1744	56149621
Osteomalacia	14.62	9.33	13	140689	700	56150665
Substance dependence	14.53	9.33	8	140694	196	56151169
Fracture pain	14.44	9.33	10	140692	372	56150993
Bradycardia	14.42	9.33	104	140598	67400	56083965
Homicide	14.40	9.33	10	140692	374	56150991
Amnesia	14.35	9.33	178	140524	46144	56105221
Breast cancer	14.29	9.33	68	140634	48765	56102600
Self-injurious ideation	14.27	9.33	23	140679	2327	56149038
Noninfectious peritonitis	14.23	9.33	7	140695	135	56151230
Intestinal fibrosis	14.18	9.33	7	140695	136	56151229
Dyspepsia	14.15	9.33	290	140412	83181	56068184
Hypomagnesaemia	14.11	9.33	109	140593	24906	56126459
Alcoholic	14.09	9.33	5	140697	40	56151325
Nephroangiosclerosis	14.04	9.33	7	140695	139	56151226
Low turnover osteopathy	14.04	9.33	31	140671	3977	56147388
Condition aggravated	13.98	9.33	712	139990	344186	55807179
Acute respiratory failure	13.75	9.33	128	140574	30866	56120499
Intentional self-injury	13.60	9.33	108	140594	24884	56126481
Hyperparathyroidism secondary	13.58	9.33	17	140685	1362	56150003
Creatinine renal clearance decreased	13.53	9.33	72	140630	14487	56136878
Blood calcium increased	13.50	9.33	48	140654	8106	56143259
Substance use disorder	13.48	9.33	7	140695	152	56151213
Joint range of motion decreased	13.47	9.33	109	140593	25256	56126109
Sensory loss	13.45	9.33	51	140651	8884	56142481
Poliomyelitis	13.38	9.33	5	140697	47	56151318
Device issue	13.36	9.33	20	140682	21086	56130279
Mydriasis	13.35	9.33	59	140643	11012	56140353
Inappropriate antidiuretic hormone secretion	13.32	9.33	9	140693	13747	56137618
Induced abortion failed	13.29	9.33	8	140694	233	56151132
Spinal cord injury lumbar	13.20	9.33	5	140697	49	56151316
Hypermagnesaemia	13.03	9.33	14	140688	951	56150414
Drug ineffective for unapproved indication	12.98	9.33	28	140674	25665	56125700
Failure to thrive	12.94	9.33	41	140661	6529	56144836
Weight decreased	12.87	9.33	730	139972	239984	55911381
Periarticular disorder	12.85	9.33	5	140697	53	56151312
Malabsorption	12.76	9.33	29	140673	3792	56147573
Device malfunction	12.62	9.33	13	140689	16123	56135242
Oncocytoma	12.54	9.33	4	140698	22	56151343
Obstructive airways disorder	12.50	9.33	80	140622	17202	56134163
Shunt occlusion	12.42	9.33	11	140691	589	56150776
Myelocyte count increased	12.40	9.33	9	140693	361	56151004
Skin ulcer	12.36	9.33	52	140650	38556	56112809
Gastrointestinal procedural complication	12.34	9.33	7	140695	182	56151183
Product storage error	12.33	9.33	9	140693	13204	56138161
Blood ethanol increased	12.32	9.33	6	140696	113	56151252
Screaming	12.29	9.33	25	140677	3029	56148336
Tenosynovitis	12.27	9.33	8	140694	12453	56138912
Drug reaction with eosinophilia and systemic symptoms	12.24	9.33	37	140665	30267	56121098
Anti-cyclic citrullinated peptide antibody	12.15	9.33	28	140674	3695	56147670
Colitis ulcerative	11.99	9.33	103	140599	24288	56127077
Chronic sinusitis	11.94	9.33	47	140655	8331	56143034
Device difficult to use	11.90	9.33	6	140696	10755	56140610
Bronchopulmonary aspergillosis	11.87	9.33	3	140699	8261	56143104
COVID-19	11.87	9.33	125	140577	74933	56076432
Motor dysfunction	11.86	9.33	51	140651	9406	56141959
Blood urea increased	11.85	9.33	103	140599	24370	56126995
Dysarthria	11.83	9.33	151	140551	39399	56111966
Asthenia	11.82	9.33	1003	139699	341970	55809395
Sciatica	11.82	9.33	30	140672	25980	56125385
Hepatic enzyme increased	11.79	9.33	332	140370	171052	55980313
Neoplasm malignant	11.64	9.33	111	140591	26944	56124421
Breath sounds abnormal	11.62	9.33	49	140653	8958	56142407
Anti-erythropoietin antibody positive	11.60	9.33	9	140693	400	56150965
Exposure during pregnancy	11.58	9.33	256	140446	136086	56015279
Injection site urticaria	11.55	9.33	9	140693	12774	56138591
Anal incontinence	11.55	9.33	61	140641	12237	56139128
Congenital knee deformity	11.54	9.33	5	140697	71	56151294
Congestive hepatopathy	11.47	9.33	22	140680	2554	56148811
Duodenitis	11.40	9.33	26	140676	3408	56147957
Congenital umbilical hernia	11.38	9.33	8	140694	305	56151060
Hyperparathyroidism	11.38	9.33	22	140680	2570	56148795
Hyperhidrosis	11.37	9.33	166	140536	93922	56057443
Toxic epidermal necrolysis	11.32	9.33	94	140608	21948	56129417
Postmortem blood drug level	11.28	9.33	6	140696	137	56151228
Blindness	11.14	9.33	18	140684	18403	56132962
Metabolic alkalosis	11.08	9.33	23	140679	2828	56148537
Product communication issue	11.07	9.33	9	140693	428	56150937
Parathyroid gland enlargement	10.96	9.33	4	140698	35	56151330
Ulcer	10.95	9.33	25	140677	22460	56128905
Abscess soft tissue	10.90	9.33	6	140696	147	56151218
Spinal compression fracture	10.90	9.33	63	140639	13071	56138294
Diverticular perforation	10.87	9.33	25	140677	3295	56148070
Nephrogenic systemic fibrosis	10.83	9.33	30	140672	4435	56146930
Cholestasis	10.77	9.33	33	140669	26880	56124485
Arthritis	10.77	9.33	180	140522	99672	56051693
Unresponsive to stimuli	10.74	9.33	124	140578	31601	56119764
Pancreatitis chronic	10.72	9.33	20	140682	2274	56149091
Loss of consciousness	10.65	9.33	353	140349	108996	56042369
Cytomegalovirus infection	10.63	9.33	20	140682	19276	56132089
Blood creatinine increased	10.60	9.33	269	140433	79922	56071443
Injection site haemorrhage	10.56	9.33	25	140677	22176	56129189
Cognitive disorder	10.52	9.33	177	140525	48956	56102409
Femur fracture	10.50	9.33	147	140555	39148	56112217
Amputation	10.48	9.33	6	140696	159	56151206
Pharyngo-oesophageal diverticulum	10.39	9.33	3	140699	11	56151354
Jaundice acholuric	10.37	9.33	5	140697	92	56151273
Surgery	10.24	9.33	44	140658	32442	56118923
Liver function test increased	10.22	9.33	36	140666	28097	56123268
Discoloured vomit	10.06	9.33	11	140691	762	56150603
Oesophagogastric fundoplasty	10.00	9.33	5	140697	100	56151265
Sinus disorder	9.90	9.33	87	140615	20647	56130718
Blood ethanol	9.84	9.33	4	140698	48	56151317
Periorbital cellulitis	9.84	9.33	10	140692	637	56150728
Hyperphosphataemia	9.84	9.33	18	140684	2017	56149348
Aggression	9.82	9.33	91	140611	21915	56129450
Amphetamines positive	9.81	9.33	6	140696	180	56151185
Musculoskeletal pain	9.79	9.33	269	140433	80883	56070482
Renal tubular dysfunction	9.76	9.33	8	140694	385	56150980
Tendonitis	9.76	9.33	19	140683	18078	56133287
Poisoning	9.70	9.33	60	140642	12753	56138612
Osteopenia	9.66	9.33	78	140624	18063	56133302
Arteriosclerosis	9.65	9.33	48	140654	9405	56141960
Erythema multiforme	9.59	9.33	6	140696	9548	56141817
Arthropathy	9.59	9.33	406	140296	199869	55951496
C-reactive protein abnormal	9.56	9.33	137	140565	36672	56114693
Mental status changes	9.51	9.33	139	140563	37362	56114003
Cardiac failure congestive	9.50	9.33	158	140544	87562	56063803
Bursitis	9.43	9.33	108	140594	27474	56123891
Aplasia pure red cell	9.39	9.33	28	140674	4314	56147051

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Drug abuse	2291.00	9.95	1845	78803	85913	31530783
Completed suicide	1681.89	9.95	1576	79072	89938	31526758
Toxicity to various agents	1317.24	9.95	1938	78710	179549	31437147
Cardio-respiratory arrest	363.52	9.95	546	80102	51180	31565516
Alcohol abuse	347.27	9.95	188	80460	4376	31612320
Intentional overdose	339.19	9.95	470	80178	40919	31575777
Alcohol interaction	321.01	9.95	152	80496	2637	31614059
Overdose	226.86	9.95	596	80052	84068	31532628
Drug ineffective	212.87	9.95	430	80218	395143	31221553
Suspected suicide	205.75	9.95	129	80519	3978	31612718
Intentional product misuse	197.68	9.95	350	80298	37601	31579095
Milk-alkali syndrome	184.64	9.95	64	80584	464	31616232
Suicide attempt	176.83	9.95	330	80318	36918	31579778
Alcohol poisoning	157.33	9.95	99	80549	3072	31613624
Substance abuse	132.14	9.95	124	80524	7034	31609662
Drug dependence	113.37	9.95	205	80443	22374	31594322
Diarrhoea	111.83	9.95	1377	79271	351032	31265664
Alcohol use	95.96	9.95	73	80575	3094	31613602
Off label use	76.44	9.95	544	80104	346730	31269966
Poisoning deliberate	71.78	9.95	91	80557	7253	31609443
Exposure to toxic agent	68.21	9.95	55	80593	2540	31614156
Blood alcohol increased	67.91	9.95	35	80613	734	31615962
Asphyxia	67.19	9.95	78	80570	5673	31611023
Respiratory depression	64.42	9.95	125	80523	14385	31602311
Shunt stenosis	60.83	9.95	32	80616	701	31615995
Myocardial infarction	59.21	9.95	125	80523	113329	31503367
Product use in unapproved indication	58.08	9.95	102	80546	99069	31517627
Respiratory arrest	55.65	9.95	170	80478	26087	31590609
Hypercalcaemia	55.44	9.95	115	80533	13885	31602811
Blood mercury abnormal	51.91	9.95	20	80628	202	31616494
Coma	50.39	9.95	223	80425	40927	31575769
5-hydroxyindolacetic acid in urine increased	49.99	9.95	20	80628	225	31616471
Rheumatoid arthritis	46.96	9.95	32	80616	47777	31568919
Treatment failure	46.17	9.95	23	80625	40769	31575927
Aggression	42.61	9.95	198	80450	37093	31579603
Cardiac arrest	39.63	9.95	373	80275	88689	31528007
Calciphylaxis	39.50	9.95	28	80620	1063	31615633
Drug resistance	37.69	9.95	7	80641	23446	31593250
Intentional product use issue	37.31	9.95	234	80414	49113	31567583
Drug hypersensitivity	37.01	9.95	81	80567	72518	31544178
Hypocalcaemia	36.47	9.95	131	80517	21847	31594849
Substance use disorder	35.68	9.95	20	80628	499	31616197
Alcohol withdrawal syndrome	35.51	9.95	29	80619	1364	31615332
Hungry bone syndrome	35.23	9.95	12	80636	82	31616614
Incorrect route of product administration	35.16	9.95	86	80562	11587	31605109
Product dose omission issue	34.32	9.95	145	80503	105441	31511255
Granulomatous pneumonitis	31.90	9.95	9	80639	29	31616667
Alcohol intolerance	31.45	9.95	17	80631	394	31616302
Small intestinal obstruction	30.22	9.95	89	80559	13383	31603313
Psoriasis	30.19	9.95	45	80603	46674	31570022
Therapeutic product effect decreased	29.95	9.95	22	80626	31600	31585096
Ex-drug abuser	29.46	9.95	12	80636	142	31616554
Mydriasis	28.54	9.95	56	80592	6496	31610200
Drug withdrawal syndrome	27.97	9.95	108	80540	18642	31598054
Interstitial lung disease	27.73	9.95	73	80575	61330	31555366
Methaemoglobinaemia	27.42	9.95	36	80612	2970	31613726
Ileus	27.41	9.95	93	80555	15076	31601620
Shunt occlusion	27.06	9.95	20	80628	811	31615885
Low density lipoprotein decreased	26.88	9.95	22	80626	1038	31615658
Pouchitis	26.65	9.95	18	80630	631	31616065
Dehydration	26.49	9.95	438	80210	118673	31498023
Hyperparathyroidism secondary	25.79	9.95	25	80623	1476	31615220
Intentional self-injury	25.27	9.95	83	80565	13232	31603464
Drug intolerance	24.94	9.95	60	80588	51973	31564723
Nephrogenic systemic fibrosis	23.90	9.95	39	80609	3916	31612780
Drug use disorder	23.70	9.95	39	80609	3944	31612752
Nasal polyps	23.01	9.95	27	80621	1986	31614710
Open reduction of fracture	22.68	9.95	9	80639	99	31616597
Metabolic alkalosis	22.61	9.95	22	80626	1305	31615391
Foetal exposure during pregnancy	22.17	9.95	44	80604	40832	31575864
Poisoning	21.75	9.95	67	80581	10324	31606372
Miosis	21.54	9.95	59	80589	8511	31608185
Rash	21.47	9.95	372	80276	201114	31415582
Blood parathyroid hormone increased	21.33	9.95	22	80626	1400	31615296
Atypical fracture	21.13	9.95	9	80639	120	31616576
Respiratory symptom	21.04	9.95	21	80627	1285	31615411
Calcinosis	20.97	9.95	16	80632	681	31616015
Drug screen positive	20.64	9.95	36	80612	3816	31612880
Angioedema	20.18	9.95	34	80614	33584	31583112
Gastrointestinal obstruction	20.18	9.95	16	80632	721	31615975
Drug ineffective for unapproved indication	20.17	9.95	10	80638	17780	31598916
Foetal alcohol syndrome	20.12	9.95	9	80639	136	31616560
Growth hormone deficiency	19.78	9.95	11	80637	270	31616426
Cardiac failure	19.59	9.95	133	80515	85820	31530876
Joint swelling	19.51	9.95	70	80578	53361	31563335
Enterocolonic fistula	19.39	9.95	8	80640	98	31616598
Accidental death	19.37	9.95	26	80622	2191	31614505
Alcoholism	18.52	9.95	32	80616	3367	31613329
Haematopoietic stem cell mobilisation	18.50	9.95	9	80639	166	31616530
Enterocolitis bacterial	18.30	9.95	11	80637	314	31616382
N-telopeptide urine increased	18.14	9.95	6	80642	37	31616659
Abdominal distension	18.10	9.95	203	80445	50481	31566215
Fractional exhaled nitric oxide increased	17.91	9.95	14	80634	618	31616078
Anaphylactic reaction	17.64	9.95	30	80618	29523	31587173
Myelosuppression	17.51	9.95	8	80640	14912	31601784
Hypophosphatasia	17.49	9.95	6	80642	42	31616654
Red blood cell count decreased	17.17	9.95	122	80526	26685	31590011
Product prescribing error	16.93	9.95	15	80633	19627	31597069
Chronic sinusitis	16.83	9.95	22	80626	1807	31614889
Accident at work	16.60	9.95	14	80634	689	31616007
Drug reaction with eosinophilia and systemic symptoms	16.55	9.95	32	80616	29986	31586710
Crohn's disease	16.49	9.95	34	80614	4087	31612609
Condition aggravated	16.45	9.95	306	80342	163703	31452993
Chest pain	16.23	9.95	205	80443	116752	31499944
Impaired driving ability	16.18	9.95	25	80623	2396	31614300
Hepatic neoplasm	16.04	9.95	22	80626	1893	31614803
Renal tubular dysfunction	15.81	9.95	11	80637	405	31616291
Intestinal obstruction	15.73	9.95	98	80550	20512	31596184
Antineutrophil cytoplasmic antibody positive	15.65	9.95	13	80635	626	31616070
Colitis	15.59	9.95	143	80505	33744	31582952
Electrocardiogram QT prolonged	15.36	9.95	156	80492	37831	31578865
Synovitis	15.35	9.95	6	80642	12277	31604419
Musculoskeletal stiffness	15.18	9.95	54	80594	41271	31575425
Dextrocardia	15.18	9.95	7	80641	114	31616582
Psoriatic arthropathy	15.06	9.95	17	80631	19866	31596830
Homicide	15.04	9.95	15	80633	917	31615779
Nerve degeneration	14.97	9.95	8	80640	181	31616515
Urogenital fistula	14.93	9.95	3	80645	0	31616696
Renal impairment	14.90	9.95	144	80504	86205	31530491
Bone density decreased	14.63	9.95	20	80628	1715	31614981
Hepatic fibrosis	14.38	9.95	31	80617	3843	31612853
Type 2 diabetes mellitus	14.37	9.95	10	80638	14774	31601922
Metabolic acidosis	14.35	9.95	159	80489	39418	31577278
Erythema	14.34	9.95	133	80515	80272	31536424
Femur fracture	14.33	9.95	47	80601	7486	31609210
Fatty liver alcoholic	14.29	9.95	6	80642	77	31616619
Bladder cancer	14.26	9.95	10	80638	14715	31601981
Amnesia	14.12	9.95	105	80543	23297	31593399
Injection site erythema	13.77	9.95	10	80638	14452	31602244
Substance-induced mood disorder	13.70	9.95	6	80642	86	31616610
Opiates positive	13.57	9.95	11	80637	512	31616184
Therapy interrupted	13.54	9.95	5	80643	10591	31606105
Abscess intestinal	13.48	9.95	18	80630	1509	31615187
Sensorimotor disorder	13.22	9.95	10	80638	420	31616276
Depressed level of consciousness	13.06	9.95	153	80495	38448	31578248
Gastrointestinal sounds abnormal	12.99	9.95	20	80628	1911	31614785
Physical assault	12.96	9.95	15	80633	1087	31615609
Bilirubin conjugated abnormal	12.94	9.95	6	80642	99	31616597
Coma scale abnormal	12.92	9.95	29	80619	3694	31613002
Injection site pain	12.89	9.95	45	80603	34589	31582107
Macrognathia	12.86	9.95	3	80645	3	31616693
Blood albumin decreased	12.74	9.95	64	80584	12367	31604329
Myocardial fibrosis	12.59	9.95	15	80633	1121	31615575
Flatulence	12.58	9.95	87	80561	18861	31597835
Mean cell haemoglobin	12.48	9.95	4	80644	22	31616674
Acute myocardial infarction	12.41	9.95	77	80571	50746	31565950
Therapeutic product effect incomplete	12.41	9.95	63	80585	43633	31573063
Diabetes mellitus	12.29	9.95	61	80587	42495	31574201
Central nervous system mass	12.27	9.95	6	80642	112	31616584
Wall motion score index abnormal	12.22	9.95	6	80642	113	31616583
Neuroleptic malignant syndrome	12.16	9.95	15	80633	16854	31599842
Blood immunoglobulin E increased	12.15	9.95	21	80627	2210	31614486
Arthropathy	12.11	9.95	27	80621	24024	31592672
SARS-CoV-2 antibody test positive	12.07	9.95	9	80639	370	31616326
Premature baby	12.06	9.95	17	80631	18049	31598647
Blood ethanol increased	12.05	9.95	10	80638	481	31616215
Weight increased	12.03	9.95	144	80504	82803	31533893
Systemic inflammatory response syndrome	11.99	9.95	39	80609	6186	31610510
Wrong technique in product usage process	11.96	9.95	44	80604	33299	31583397
Delirium tremens	11.96	9.95	11	80637	608	31616088
Contraindicated product administered	11.86	9.95	20	80628	19752	31596944
Compartment syndrome	11.84	9.95	23	80625	2648	31614048
Chronic obstructive pulmonary disease	11.78	9.95	67	80581	45099	31571597
Headache	11.69	9.95	367	80281	183285	31433411
Multiple organ dysfunction syndrome	11.66	9.95	114	80534	68089	31548607
Calcification metastatic	11.65	9.95	3	80645	6	31616690
Frequent bowel movements	11.64	9.95	54	80594	10105	31606591
Necrotising ulcerative gingivostomatitis	11.52	9.95	5	80643	70	31616626
Hospitalisation	11.38	9.95	77	80571	49730	31566966
Acrochordon	11.30	9.95	8	80640	303	31616393
Arthralgia	11.30	9.95	296	80352	151128	31465568
Blood ethanol	11.27	9.95	5	80643	74	31616622
Infection	11.22	9.95	144	80504	81787	31534909
Tachycardia	11.10	9.95	263	80385	75944	31540752
Drug abuser	11.06	9.95	28	80620	3852	31612844
Haematocrit decreased	11	9.95	121	80527	29940	31586756
Tendonitis	11.00	9.95	4	80644	8554	31608142
Arrhythmia	11.00	9.95	45	80603	33032	31583664
Abdominal pain	10.98	9.95	465	80183	145487	31471209
Blood 25-hydroxycholecalciferol decreased	10.93	9.95	7	80641	224	31616472
Alcoholic liver disease	10.88	9.95	10	80638	552	31616144
Oesophageal perforation	10.85	9.95	13	80635	977	31615719
Drug diversion	10.81	9.95	12	80636	831	31615865
Road traffic accident	10.75	9.95	75	80573	16306	31600390
Hyperphosphataemia	10.75	9.95	21	80627	2428	31614268
Blood calcium increased	10.67	9.95	25	80623	3277	31613419
Coronary artery disease	10.65	9.95	71	80577	46016	31570680
Post procedural diarrhoea	10.65	9.95	5	80643	85	31616611
Rectal prolapse	10.63	9.95	9	80639	445	31616251
Disease progression	10.61	9.95	164	80484	90300	31526396
Vascular device infection	10.60	9.95	25	80623	3290	31613406
Renal cyst haemorrhage	10.51	9.95	10	80638	577	31616119
Disorientation	10.46	9.95	122	80526	30622	31586074
Prescribed underdose	10.42	9.95	4	80644	8274	31608422
Withdrawal syndrome	10.42	9.95	58	80590	11659	31605037
Psychiatric disorder prophylaxis	10.42	9.95	4	80644	40	31616656
Accidental poisoning	10.41	9.95	11	80637	720	31615976
Thrombocytopenia	10.40	9.95	280	80368	142467	31474229
Pneumonia aspiration	10.36	9.95	147	80501	38579	31578117
Muscle swelling	10.33	9.95	8	80640	348	31616348
Diabetic ketoacidosis	10.24	9.95	17	80631	16888	31599808
Immune reconstitution inflammatory syndrome	10.21	9.95	4	80644	8174	31608522
Airway remodelling	10.21	9.95	6	80642	164	31616532
Hepatocellular injury	10.19	9.95	25	80623	21519	31595177
Peripheral swelling	10.15	9.95	117	80531	67748	31548948
Sopor	10.15	9.95	57	80591	11495	31605201
Liver disorder	10.14	9.95	40	80608	29667	31587029
Proctalgia	10.10	9.95	30	80618	4532	31612164
Blood potassium decreased	10.08	9.95	74	80574	16352	31600344
Pain	10.07	9.95	381	80267	186378	31430318
Atopy	10.02	9.95	6	80642	170	31616526

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Completed suicide	3442.94	9.48	3505	175251	223630	70526058
Drug abuse	2648.84	9.48	2498	176258	144758	70604930
Toxicity to various agents	2126.63	9.48	3598	175158	378574	70371114
Cardio-respiratory arrest	734.16	9.48	1076	177680	99601	70650087
Intentional overdose	514.23	9.48	904	177852	97531	70652157
Alcohol interaction	496.38	9.48	240	178516	4413	70745275
Milk-alkali syndrome	484.29	9.48	162	178594	1051	70748637
Drug ineffective	416.32	9.48	1117	177639	938635	69811053
Suspected suicide	357.81	9.48	242	178514	8592	70741096
Alcohol abuse	339.85	9.48	192	178564	4915	70744773
Overdose	338.97	9.48	1069	177687	168676	70581012
Alcohol poisoning	229.71	9.48	141	178615	4224	70745464
Intentional product misuse	218.97	9.48	563	178193	79032	70670656
Suicide attempt	206.05	9.48	550	178206	78960	70670728
Diarrhoea	198.10	9.48	2916	175840	780425	69969263
Coma	172.77	9.48	567	178189	91277	70658411
Rheumatoid arthritis	167.85	9.48	299	178457	291506	70458182
Alcohol use	159.89	9.48	115	178641	4512	70745176
Hypocalcaemia	139.92	9.48	333	178423	44526	70705162
Respiratory arrest	134.60	9.48	368	178388	53565	70696123
Substance abuse	120.32	9.48	136	178620	9701	70739987
Asphyxia	118.10	9.48	138	178618	10204	70739484
Hypercalcaemia	113.51	9.48	261	178495	34124	70715564
Off label use	110.89	9.48	1269	177487	741791	70007897
Exposure to toxic agent	110.77	9.48	105	178651	6089	70743599
Drug hypersensitivity	105.11	9.48	326	178430	262133	70487555
Blood alcohol increased	95.44	9.48	51	178705	1166	70748522
Drug dependence	94.46	9.48	256	178500	37065	70712623
Pneumonia aspiration	86.92	9.48	349	178407	61940	70687748
Product dose omission issue	83.63	9.48	275	178481	217193	70532495
Methaemoglobinaemia	81.55	9.48	79	178677	4707	70744981
Shunt stenosis	81.06	9.48	47	178709	1265	70748423
Poisoning deliberate	77.97	9.48	148	178608	16912	70732776
Cardiac arrest	70.37	9.48	663	178093	159171	70590517
Myocardial infarction	69.52	9.48	212	178544	171433	70578255
Hypomania	67.63	9.48	80	178676	5992	70743696
Gastrooesophageal reflux disease	63.29	9.48	419	178337	90420	70659268
Small intestinal obstruction	62.26	9.48	169	178587	24486	70725202
Liver injury	62.18	9.48	236	178520	40799	70708889
Nephrocalcinosis	60.63	9.48	40	178716	1361	70748327
Therapeutic product effect decreased	59.82	9.48	174	178582	142844	70606844
Somnolence	59.38	9.48	816	177940	214790	70534898
Product use in unapproved indication	58.61	9.48	296	178460	207182	70542506
Drug resistance	57.24	9.48	13	178743	38177	70711511
Dehydration	56.35	9.48	841	177915	225301	70524387
Sleep disorder due to general medical condition, insomnia type	55.94	9.48	11	178745	35721	70713967
Calciphylaxis	53.02	9.48	54	178702	3419	70746269
Infusion related reaction	52.88	9.48	287	178469	197247	70552441
Rash	52.88	9.48	937	177819	509625	70240063
Blood mercury abnormal	52.09	9.48	20	178736	202	70749486
Recalled product	50.85	9.48	31	178725	917	70748771
Calcium ionised decreased	50.35	9.48	26	178730	553	70749135
Abdominal pain	50.24	9.48	1172	177584	340955	70408733
5-hydroxyindolacetic acid in urine increased	50.02	9.48	20	178736	227	70749461
Substance use disorder	49.69	9.48	27	178729	639	70749049
Segmental diverticular colitis	49.30	9.48	18	178738	156	70749532
Infection	49.15	9.48	320	178436	210465	70539223
Contraindicated product administered	49.15	9.48	174	178582	134438	70615250
Neurologic neglect syndrome	47.69	9.48	43	178713	2338	70747350
Treatment failure	47.66	9.48	194	178562	143948	70605740
Postmortem blood drug level abnormal	47.56	9.48	26	178730	623	70749065
Drug intolerance	47.52	9.48	353	178403	225334	70524354
Pedal pulse abnormal	47.40	9.48	18	178738	176	70749512
Injection site erythema	47.23	9.48	69	178687	72855	70676833
Feeding intolerance	46.64	9.48	26	178730	648	70749040
Jaundice cholestatic	46.15	9.48	83	178673	9101	70740587
Myelosuppression	45.71	9.48	10	178746	30135	70719553
Facet joint syndrome	45.44	9.48	66	178690	6047	70743641
Headache	45.14	9.48	1116	177640	579289	70170399
Pain	44.70	9.48	1225	177531	627591	70122097
Blood calcium decreased	43.78	9.48	166	178590	28680	70721008
Lip dry	43.62	9.48	84	178672	9701	70739987
Injection site bruising	41.49	9.48	22	178734	38010	70711678
Injection site pain	40.99	9.48	155	178601	117464	70632224
Pruritus	40.05	9.48	621	178135	344939	70404749
Carotid artery thrombosis	39.62	9.48	40	178716	2506	70747182
Anaphylactic reaction	39.37	9.48	81	178675	74893	70674795
Joint swelling	38.91	9.48	429	178327	252782	70496906
Vomiting	38.71	9.48	1846	176910	591265	70158423
Gastrointestinal disorder	38.67	9.48	136	178620	105291	70644397
Arthropathy	38.53	9.48	221	178535	149836	70599852
Angioedema	38.45	9.48	68	178688	66542	70683146
Tetany	38.02	9.48	37	178719	2217	70747471
Drug ineffective for unapproved indication	36.87	9.48	26	178730	38512	70711176
Hungry bone syndrome	36.84	9.48	15	178741	179	70749509
Device expulsion	36.66	9.48	6	178750	22240	70727448
Injection site reaction	36.55	9.48	43	178713	49809	70699879
Drug use disorder	36.37	9.48	70	178686	8081	70741607
Hypophosphataemic osteomalacia	36.30	9.48	17	178739	290	70749398
Coronary artery disease	35.36	9.48	65	178691	62671	70687017
Shunt occlusion	35.35	9.48	29	178727	1386	70748302
Schizophrenia	34.68	9.48	107	178649	16661	70733027
Respiratory depression	34.52	9.48	139	178617	24692	70724996
Alcoholism	34.52	9.48	49	178707	4396	70745292
Nasal obstruction	34.29	9.48	30	178726	1567	70748121
Incorrect route of product administration	34.24	9.48	145	178611	26347	70723341
Injection site swelling	34.10	9.48	35	178721	43122	70706566
Aggression	34.06	9.48	224	178532	48222	70701466
Ill-defined disorder	33.33	9.48	54	178702	54687	70695001
Weight increased	33.21	9.48	421	178335	241910	70507778
Hepatotoxicity	33.15	9.48	207	178549	43779	70705909
Peripheral venous disease	32.95	9.48	79	178677	10608	70739080
Synovitis	32.81	9.48	191	178565	129037	70620651
Hypersensitivity	32.72	9.48	396	178360	229416	70520272
Sinusitis	32.64	9.48	271	178485	168924	70580764
Throat clearing	32.51	9.48	30	178726	1681	70748007
Abdominal distension	32.48	9.48	405	178351	104264	70645424
Full blood count abnormal	31.79	9.48	169	178587	33709	70715979
Nicotine dependence	31.18	9.48	22	178734	837	70748851
Intentional self-injury	31.16	9.48	160	178596	31490	70718198
Intentional product use issue	31.15	9.48	450	178306	119692	70629996
Arthralgia	30.90	9.48	1000	177756	502390	70247298
Flatulence	30.88	9.48	183	178573	37998	70711690
Nephrogenic systemic fibrosis	30.80	9.48	55	178701	5997	70743691
Arteriosclerosis coronary artery	30.36	9.48	100	178656	16115	70733573
Drug reaction with eosinophilia and systemic symptoms	30.19	9.48	63	178693	57950	70691738
Dyspnoea	30.05	9.48	1611	177145	768449	69981239
Metabolic alkalosis	29.96	9.48	44	178712	4072	70745616
Mydriasis	29.70	9.48	99	178657	16054	70733634
Injection site pruritus	29.64	9.48	33	178723	39177	70710511
Stress fracture	29.56	9.48	53	178703	5797	70743891
Hepatocellular injury	29.46	9.48	44	178712	46047	70703641
Wrong technique in product usage process	29.13	9.48	83	178673	68615	70681073
Hyperparathyroidism secondary	28.98	9.48	34	178722	2524	70747164
Personality disorder	28.98	9.48	51	178705	5497	70744191
Alcohol withdrawal syndrome	28.79	9.48	29	178727	1812	70747876
Cytomegalovirus infection	28.40	9.48	35	178721	39723	70709965
Product quality issue	27.46	9.48	22	178734	30539	70719149
Granulomatous pneumonitis	27.06	9.48	10	178746	90	70749598
Gastrointestinal sounds abnormal	27.06	9.48	47	178709	5014	70744674
Lower respiratory tract infection	27.04	9.48	168	178588	111745	70637943
Arteriovenous fistula occlusion	27.03	9.48	17	178739	532	70749156
Maternal exposure during pregnancy	26.92	9.48	175	178581	115170	70634518
Depressed level of consciousness	26.57	9.48	337	178419	87094	70662594
Low turnover osteopathy	26.46	9.48	28	178728	1854	70747834
Pouchitis	26.06	9.48	20	178736	867	70748821
Drug eruption	25.93	9.48	37	178719	39459	70710229
Low density lipoprotein decreased	25.83	9.48	22	178734	1108	70748580
Abdominal rigidity	25.71	9.48	33	178723	2688	70747000
Nasal polyps	25.54	9.48	43	178713	4473	70745215
Colitis	24.79	9.48	258	178498	63556	70686132
Rib deformity	24.76	9.48	11	178745	165	70749523
Therapy cessation	24.74	9.48	29	178727	33647	70716041
Accidental death	24.52	9.48	39	178717	3869	70745819
Gonorrhoea	24.41	9.48	11	178745	171	70749517
Herpes zoster	24.39	9.48	121	178635	85114	70664574
Condition aggravated	24.24	9.48	858	177898	426777	70322911
Ileus	24.19	9.48	123	178633	24114	70725574
Blood parathyroid hormone increased	24.13	9.48	35	178721	3202	70746486
Salivary gland calculus	23.90	9.48	12	178744	240	70749448
Peripheral swelling	23.83	9.48	436	178320	236127	70513561
Sputum purulent	23.76	9.48	22	178734	1238	70748450
Adjustment disorder	23.45	9.48	34	178722	3110	70746578
Chronic sinusitis	23.45	9.48	60	178696	8391	70741297
Erythema	23.30	9.48	358	178398	199205	70550483
Homicide	23.18	9.48	21	178735	1149	70748539
Product prescribing error	23.18	9.48	39	178717	38913	70710775
Intestinal obstruction	22.89	9.48	172	178584	38653	70711035
Poisoning	22.71	9.48	115	178641	22507	70727181
Red blood cell sedimentation rate increased	22.71	9.48	39	178717	38603	70711085
Systemic lupus erythematosus	22.58	9.48	157	178599	101745	70647943
Failure to thrive	22.30	9.48	69	178687	10760	70738928
Frequent bowel movements	22.28	9.48	109	178647	21044	70728644
Renal impairment	22.03	9.48	244	178512	143693	70605995
Skin haemorrhage	22.02	9.48	66	178690	10114	70739574
Blood ethanol increased	21.93	9.48	16	178740	642	70749046
Urticaria	21.68	9.48	285	178471	162764	70586924
Victim of sexual abuse	21.68	9.48	14	178742	459	70749229
Rhinorrhoea	21.53	9.48	259	178497	66112	70683576
Open reduction of fracture	21.43	9.48	11	178745	231	70749457
Hand deformity	21.32	9.48	129	178627	86353	70663335
Opiates positive	20.87	9.48	18	178738	922	70748766
Blood ethanol	20.82	9.48	9	178747	126	70749562
Neuroleptic malignant syndrome	20.65	9.48	21	178735	25986	70723702
Multiple sclerosis relapse	20.51	9.48	49	178707	42968	70706720
Interstitial lung disease	20.49	9.48	167	178589	104518	70645170
Pemphigus	20.40	9.48	124	178632	82912	70666776
Head banging	20.16	9.48	14	178742	519	70749169
Cholelithiasis	20.13	9.48	195	178561	47145	70702543
Haematotoxicity	19.81	9.48	5	178751	13669	70736019
Eating disorder	19.79	9.48	96	178660	18469	70731219
Post procedural diarrhoea	19.76	9.48	14	178742	536	70749152
Musculoskeletal disorder	19.74	9.48	13	178743	19958	70729730
Hypokalaemia	19.69	9.48	451	178305	130737	70618951
Chronic kidney disease-mineral and bone disorder	19.45	9.48	15	178741	655	70749033
Cardiac failure congestive	19.42	9.48	233	178523	135224	70614464
Inappropriate antidiuretic hormone secretion	19.40	9.48	18	178738	23258	70726430
Affect lability	19.38	9.48	63	178693	10083	70739605
Therapeutic reaction time decreased	19.24	9.48	28	178728	2569	70747119
Hepatic function abnormal	19.18	9.48	97	178659	67899	70681789
Sleep disorder due to a general medical condition	19.07	9.48	64	178692	10412	70739276
Blue toe syndrome	19.03	9.48	14	178742	569	70749119
Psoriasis	18.82	9.48	158	178598	98275	70651413
Bone marrow failure	18.79	9.48	62	178694	48948	70700740
Blood potassium decreased	18.66	9.48	176	178580	42245	70707443
Therapy interrupted	18.61	9.48	21	178735	24781	70724907
Hypophosphataemia	18.55	9.48	86	178670	16240	70733448
Substance dependence	18.51	9.48	13	178743	491	70749197
Red blood cell sedimentation rate abnormal	18.50	9.48	13	178743	19290	70730398
Nephroangiosclerosis	18.42	9.48	11	178745	313	70749375
Alcohol intolerance	18.33	9.48	12	178744	403	70749285
Vascular device infection	18.27	9.48	53	178703	7977	70741711
Death	18.22	9.48	1507	177249	508554	70241134
Hyperphosphataemia	18.20	9.48	36	178720	4240	70745448
Abortion spontaneous	18.20	9.48	24	178732	26455	70723233
Miosis	18.08	9.48	77	178679	14024	70735664
Chemical submission	18.02	9.48	10	178746	247	70749441
Swelling	17.90	9.48	351	178405	188188	70561500
Intramedullary rod insertion	17.88	9.48	9	178747	181	70749507
Amphetamines positive	17.80	9.48	10	178746	253	70749435
Coordination abnormal	17.80	9.48	84	178672	15982	70733706
Haemorrhoids	17.79	9.48	118	178638	25470	70724218
Hypoparathyroidism	17.77	9.48	17	178739	997	70748691
N-telopeptide urine increased	17.67	9.48	6	178750	41	70749647
Multiple drug therapy	17.53	9.48	30	178726	3162	70746526
Joint range of motion decreased	17.49	9.48	119	178637	25907	70723781
Femur fracture	17.47	9.48	153	178603	35979	70713709
Venoocclusive liver disease	17.33	9.48	3	178753	10675	70739013
Sinus congestion	17.22	9.48	88	178668	17285	70732403
Hyperparathyroidism	17.22	9.48	29	178727	3018	70746670
Amnesia	17.13	9.48	204	178552	51951	70697737
Post transplant lymphoproliferative disorder	17.03	9.48	3	178753	10542	70739146
Urine calcium/creatinine ratio increased	16.90	9.48	8	178748	140	70749548
Postmortem blood drug level	16.77	9.48	10	178746	284	70749404
Haematopoietic stem cell mobilisation	16.72	9.48	9	178747	209	70749479
Fracture pain	16.60	9.48	11	178745	377	70749311
Delirium tremens	16.59	9.48	14	178742	696	70748992
Product storage error	16.47	9.48	8	178748	14533	70735155
Lymph node palpable	16.45	9.48	8	178748	149	70749539
Loss of personal independence in daily activities	16.36	9.48	136	178620	84774	70664914
Tendonitis	16.30	9.48	19	178737	22103	70727585
Electrocardiogram QRS complex prolonged	16.20	9.48	58	178698	9748	70739940
Hepatic neoplasm	16.18	9.48	29	178727	3171	70746517
Migraine	16.15	9.48	111	178645	72127	70677561
Enterocolonic fistula	16.12	9.48	8	178748	156	70749532
Anti-cyclic citrullinated peptide antibody positive	16.11	9.48	107	178649	70078	70679610
Bladder cancer	16.02	9.48	12	178744	17230	70732458
Obstruction	15.92	9.48	31	178725	3610	70746078
Growth hormone deficiency	15.88	9.48	11	178745	406	70749282
Compartment syndrome	15.86	9.48	35	178721	4451	70745237
Hypophosphatasia	15.86	9.48	6	178750	58	70749630
Protein C increased	15.82	9.48	7	178749	104	70749584
Toxicologic test abnormal	15.64	9.48	18	178738	1309	70748379
Chest pain	15.41	9.48	499	178257	250761	70498927
Psychotic disorder	15.39	9.48	154	178602	37547	70712141
Pathological fracture	15.25	9.48	56	178700	9527	70740161
Anti-cyclic citrullinated peptide antibody	15.02	9.48	29	178727	3356	70746332
Depression	15.02	9.48	384	178372	198590	70551098
Alopecia	15.00	9.48	383	178373	198107	70551581
Large intestine polyp	14.97	9.48	63	178693	11413	70738275
Neuralgia	14.93	9.48	31	178725	28572	70721116
Breast cancer female	14.88	9.48	4	178752	10482	70739206
Acute graft versus host disease	14.85	9.48	3	178753	9559	70740129
Blood calcium increased	14.69	9.48	53	178703	8940	70740748
Gluten sensitivity	14.66	9.48	10	178746	360	70749328
Red blood cell count decreased	14.57	9.48	198	178558	51963	70697725
Injection site rash	14.51	9.48	12	178744	16398	70733290
Device malfunction	14.49	9.48	16	178740	19068	70730620
Hip fracture	14.35	9.48	121	178635	28142	70721546
Device issue	14.34	9.48	24	178732	24001	70725687
Cardiac failure	14.30	9.48	265	178491	143276	70606412
Sneezing	14.19	9.48	82	178674	16869	70732819
Fracture nonunion	14.12	9.48	18	178738	1456	70748232
Visual acuity reduced	13.97	9.48	31	178725	27899	70721789
Wheezing	13.90	9.48	323	178433	93847	70655841
Injection site haemorrhage	13.90	9.48	27	178729	25500	70724188
Leukopenia	13.89	9.48	187	178569	106373	70643315
Device difficult to use	13.85	9.48	5	178751	10844	70738844
Hospitalisation	13.84	9.48	137	178619	82431	70667257
Hypermagnesaemia	13.78	9.48	16	178740	1175	70748513
Autoimmune colitis	13.55	9.48	18	178738	1516	70748172
Cerebral haemorrhage	13.46	9.48	80	178676	53784	70695904
Peripheral pulse decreased	13.43	9.48	5	178751	46	70749642
Device related infection	13.40	9.48	132	178624	32053	70717635
Ulcer	13.37	9.48	28	178728	25726	70723962
Atypical fracture	13.36	9.48	12	178744	649	70749039
Poliomyelitis	13.25	9.48	5	178751	48	70749640
Breast cancer	13.17	9.48	42	178714	33507	70716181
Pregnancy	13.08	9.48	25	178731	23756	70725932
Bilirubin conjugated abnormal	13.05	9.48	6	178750	98	70749590
Discomfort	13.04	9.48	187	178569	105249	70644439
Neutropenia	12.98	9.48	523	178233	256633	70493055
Hepatic fibrosis	12.97	9.48	40	178716	6227	70743461
Enterocolitis bacterial	12.86	9.48	11	178745	557	70749131
Drug screen positive	12.76	9.48	38	178718	5802	70743886
Tibia fracture	12.74	9.48	34	178722	4876	70744812
Drug abuser	12.67	9.48	38	178718	5826	70743862
Congenital knee deformity	12.67	9.48	4	178752	21	70749667
Insomnia	12.54	9.48	436	178320	217370	70532318
Electrocardiogram QT prolonged	12.49	9.48	287	178469	83230	70666458
Bradycardia	12.43	9.48	230	178526	124385	70625303
Conjunctival scar	12.43	9.48	7	178749	178	70749510
Spinal cord injury lumbar	12.41	9.48	5	178751	58	70749630
Nerve degeneration	12.37	9.48	8	178748	263	70749425
Blood bilirubin increased	12.36	9.48	216	178540	59685	70690003
Cerebral infarction	12.33	9.48	61	178695	42948	70706740
Acquired haemophilia	12.30	9.48	19	178737	1838	70747850
Constipation	12.28	9.48	765	177991	251673	70498015
Wall motion score index abnormal	12.28	9.48	6	178750	113	70749575
Blindness	12.27	9.48	25	178731	23202	70726486
Vision blurred	12.27	9.48	167	178589	94817	70654871
Liver disorder	12.14	9.48	98	178658	61470	70688218
Sensory loss	12.14	9.48	59	178697	11360	70738328
Central nervous system mass	12.13	9.48	6	178750	116	70749572
Sleep apnoea syndrome	12.12	9.48	42	178714	32671	70717017
SARS-CoV-2 antibody test positive	12.12	9.48	9	178747	371	70749317
Drug withdrawal syndrome	12.11	9.48	131	178625	32584	70717104
Diabetes mellitus	12.11	9.48	119	178637	71705	70677983
Gastrointestinal procedural complication	12.09	9.48	7	178749	188	70749500
Premature delivery	12.07	9.48	22	178734	21282	70728406
Polyarthritis	12.06	9.48	6	178750	10750	70738938
Arthritis	12.04	9.48	174	178582	97806	70651882
Induced abortion failed	12.02	9.48	7	178749	190	70749498
Substance-induced mood disorder	12.00	9.48	6	178750	119	70749569
Pulmonary calcification	11.91	9.48	9	178747	381	70749307
Myelodysplastic syndrome	11.89	9.48	37	178719	29748	70719940
Multiple organ dysfunction syndrome	11.88	9.48	197	178559	108318	70641370
Impaired healing	11.81	9.48	125	178631	74249	70675439
Shunt aneurysm	11.58	9.48	4	178752	29	70749659
Fluid retention	11.55	9.48	103	178653	63282	70686406
Heavy menstrual bleeding	11.53	9.48	9	178747	12656	70737032
Thrombocytopenia	11.49	9.48	489	178267	238621	70511067
Mucormycosis	11.48	9.48	3	178753	8011	70741677
Oncocytoma	11.46	9.48	4	178752	30	70749658
Calcification metastatic	11.44	9.48	6	178750	132	70749556
Hot flush	11.40	9.48	182	178574	49402	70700286
Sinus tachycardia	11.29	9.48	133	178623	33780	70715908
Hypovolaemia	11.27	9.48	74	178682	15919	70733769
COVID-19	11.25	9.48	193	178563	105564	70644124
Epstein-Barr virus infection	11.25	9.48	10	178746	13188	70736500
Myocardial fibrosis	11.21	9.48	17	178739	1618	70748070
Therapy partial responder	11.18	9.48	9	178747	12465	70737223
Unevaluable event	11.15	9.48	81	178675	51982	70697706
Discoloured vomit	11.09	9.48	15	178741	1286	70748402
Agitation	11.06	9.48	311	178445	93064	70656624
Exposure during pregnancy	11.05	9.48	155	178601	87562	70662126
Impaired driving ability	10.99	9.48	32	178724	4825	70744863
Cholestasis	10.98	9.48	73	178683	47799	70701889
Burning sensation	10.96	9.48	83	178673	52787	70696901
Ankylosing spondylitis	10.95	9.48	8	178748	11638	70738050
Injection site urticaria	10.94	9.48	8	178748	11630	70738058
Necrotising ulcerative gingivostomatitis	10.92	9.48	4	178752	35	70749653
Respiratory tract congestion	10.85	9.48	79	178677	17574	70732114
Blood albumin decreased	10.85	9.48	94	178662	22033	70727655
Glossodynia	10.83	9.48	153	178603	86334	70663354
Penile erythema	10.78	9.48	6	178750	149	70749539
Granuloma skin	10.77	9.48	3	178753	7679	70742009
Delayed graft function	10.77	9.48	25	178731	3288	70746400
Bronchopulmonary aspergillosis	10.76	9.48	23	178733	20979	70728709
Alcoholic	10.73	9.48	4	178752	37	70749651
Blood pressure fluctuation	10.71	9.48	96	178660	58916	70690772
Blood 25-hydroxycholecalciferol decreased	10.71	9.48	8	178748	333	70749355
Pharyngitis	10.67	9.48	22	178734	20329	70729359
Accident at work	10.63	9.48	13	178743	1008	70748680
Abscess intestinal	10.59	9.48	21	178735	2477	70747211
Pulmonary oedema	10.58	9.48	277	178479	82001	70667687
Protein total decreased	10.58	9.48	45	178711	8191	70741497
Noninfectious peritonitis	10.46	9.48	7	178749	244	70749444
Eye disorder	10.45	9.48	23	178733	20762	70728926
Psychiatric disorder prophylaxis	10.45	9.48	4	178752	40	70749648
Rhinovirus infection	10.43	9.48	39	178717	6694	70742994
Metabolic acidosis	10.36	9.48	253	178503	74093	70675595
Diffuse large B-cell lymphoma	10.27	9.48	11	178745	13291	70736397
Gastritis alcoholic	10.20	9.48	4	178752	43	70749645
No adverse event	10.17	9.48	44	178712	32109	70717579
Achlorhydria	10.16	9.48	3	178753	12	70749676
Impaired work ability	10.06	9.48	16	178740	16324	70733364
Injection site warmth	10.05	9.48	12	178744	13813	70735875
Immune thrombocytopenia	10.03	9.48	16	178740	16308	70733380
Skin necrosis	9.98	9.48	16	178740	16275	70733413
Osteomalacia	9.96	9.48	15	178741	1419	70748269
Loss of consciousness	9.96	9.48	484	178272	155232	70594456
Dysarthria	9.91	9.48	216	178540	62097	70687591
Ketoacidosis	9.89	9.48	3	178753	7266	70742422
Malabsorption	9.84	9.48	30	178726	4640	70745048
Gastrointestinal toxicity	9.83	9.48	37	178719	6368	70743320
Renal cyst haemorrhage	9.81	9.48	10	178746	634	70749054
Benzodiazepine drug level therapeutic	9.81	9.48	4	178752	48	70749640
Intraductal papillary mucinous neoplasm	9.77	9.48	11	178745	781	70748907
Pulmonary arterial hypertension	9.77	9.48	46	178710	32809	70716879
Immune reconstitution inflammatory syndrome	9.74	9.48	11	178745	12979	70736709
Rheumatic fever	9.72	9.48	77	178679	17583	70732105
Aplastic anaemia	9.70	9.48	17	178739	16699	70732989
Respiratory symptom	9.63	9.48	26	178730	3755	70745933
Labelled drug-drug interaction medication error	9.61	9.48	30	178726	24097	70725591
Malaise	9.60	9.48	950	177806	431982	70317706
Self-injurious ideation	9.57	9.48	24	178732	3314	70746374
Mixed dementia	9.55	9.48	7	178749	283	70749405
Sinus disorder	9.54	9.48	81	178675	18878	70730810
Hypomagnesaemia	9.51	9.48	150	178606	40614	70709074
Acute respiratory failure	9.50	9.48	189	178567	53476	70696212
Sensorimotor disorder	9.50	9.48	11	178745	805	70748883

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	P03AX05	ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS ECTOPARASITICIDES, INCL. SCABICIDES Other ectoparasiticides, incl. scabicides
FDA PE	N0000010282	Skin Barrier Activity
MeSH PA	D000934	Antifoaming Agents
MeSH PA	D003879	Dermatologic Agents
MeSH PA	D004643	Emollients
MeSH PA	D013501	Surface-Active Agents
CHEBI has role	CHEBI:63047	food emulsifiers
CHEBI has role	CHEBI:77965	food anti-caking agent
CHEBI has role	CHEBI:78058	food antifoaming agents

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Diaper rash	indication	91487003

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
4018922	VUID
N0000147215	NUI
D01540	KEGG_DRUG
4018922	VANDF
4019331	VANDF
C1113707	UMLSCUI
CHEBI:31498	CHEBI
CHEMBL2108200	ChEMBL_ID
DB11074	DRUGBANK_ID
CHEMBL4297192	ChEMBL_ID
CHEMBL1200838	ChEMBL_ID
24764	PUBCHEM_CID
C501844	MESH_SUPPLEMENTAL_RECORD_UI
C013830	MESH_SUPPLEMENTAL_RECORD_UI
2898	INN_ID
92RU3N3Y1O	UNII
DB09512	DRUGBANK_ID
DB14005	DRUGBANK_ID
1299921	RXNORM
4607	MMSL
5175	MMSL
5464	MMSL
d01027	MMSL
001144	NDDF
001915	NDDF
387442005	SNOMEDCT_US
396031000	SNOMEDCT_US
420874002	SNOMEDCT_US
77898008	SNOMEDCT_US
D012841	MESH_DESCRIPTOR_UI

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Gas-XExtra Strength	HUMAN OTC DRUG LABEL	1	0067-0117	TABLET, CHEWABLE	125 mg	ORAL	OTC monograph final	10 sections
Gas-XTotal Relief Maximum Strength	HUMAN OTC DRUG LABEL	2	0067-0118	TABLET, CHEWABLE	250 mg	ORAL	OTC monograph final	14 sections
Gas-XTotal Relief Maximum Strength	HUMAN OTC DRUG LABEL	2	0067-0119	TABLET, CHEWABLE	250 mg	ORAL	OTC monograph final	14 sections
Gas-XExtra Strength	HUMAN OTC DRUG LABEL	1	0067-0129	TABLET, CHEWABLE	125 mg	ORAL	OTC monograph final	10 sections
Gas-XUltra Strength AntiGas Softgels	HUMAN OTC DRUG LABEL	1	0067-6274	CAPSULE, LIQUID FILLED	180 mg	ORAL	OTC monograph final	10 sections
Gas-XExtra Strength Softgels	HUMAN OTC DRUG LABEL	1	0067-6275	CAPSULE, LIQUID FILLED	125 mg	ORAL	OTC monograph final	10 sections
Gas-XMaximum Strength Softgels	HUMAN OTC DRUG LABEL	1	0067-6283	CAPSULE, LIQUID FILLED	250 mg	ORAL	OTC monograph final	10 sections
Moisturel	HUMAN OTC DRUG LABEL	1	0093-3204	LOTION	30 g	TOPICAL	OTC monograph final	13 sections
good sense anti diarrheal anti gas	HUMAN OTC DRUG LABEL	2	0113-0087	TABLET	125 mg	ORAL	ANDA	16 sections
Good Sense antacid	HUMAN OTC DRUG LABEL	3	0113-0340	SUSPENSION	80 mg	ORAL	OTC monograph final	13 sections
Good Sense AntacidRegular Strength	HUMAN OTC DRUG LABEL	3	0113-0357	SUSPENSION	40 mg	ORAL	OTC monograph final	13 sections
Good Sense Gas ReliefExtra Strength	HUMAN OTC DRUG LABEL	1	0113-0428	CAPSULE, LIQUID FILLED	125 mg	ORAL	OTC monograph final	10 sections
Good Sense AntacidMaximum Strength	HUMAN OTC DRUG LABEL	3	0113-0588	SUSPENSION	80 mg	ORAL	OTC monograph final	13 sections
good sense gas relief	HUMAN OTC DRUG LABEL	1	0113-0657	CAPSULE, LIQUID FILLED	180 mg	ORAL	OTC monograph final	11 sections
good sense antacid	HUMAN OTC DRUG LABEL	3	0113-0851	SUSPENSION	40 mg	ORAL	OTC monograph final	13 sections
good sense simethiconeinfants	HUMAN OTC DRUG LABEL	1	0113-0882	EMULSION	20 mg	ORAL	OTC monograph final	11 sections
Good Sense Anti Diarrheal Anti Gas	HUMAN OTC DRUG LABEL	2	0113-1087	TABLET	125 mg	ORAL	ANDA	16 sections
injoy gas relief	HUMAN OTC DRUG LABEL	1	0113-6011	CAPSULE, LIQUID FILLED	125 mg	ORAL	OTC monograph final	10 sections
basic care loperamide hydrochloride and simethicone	HUMAN OTC DRUG LABEL	2	0113-7119	TABLET	125 mg	ORAL	ANDA	16 sections
Mag-AL Plus	HUMAN OTC DRUG LABEL	3	0121-1761	SUSPENSION	20 mg	ORAL	OTC monograph final	14 sections
Mag-AL Plus	HUMAN OTC DRUG LABEL	3	0121-1761	SUSPENSION	20 mg	ORAL	OTC monograph final	14 sections
Mag-AL PlusXS	HUMAN OTC DRUG LABEL	3	0121-1762	SUSPENSION	40 mg	ORAL	OTC monograph final	15 sections
Mag-AL PlusXS	HUMAN OTC DRUG LABEL	3	0121-1762	SUSPENSION	40 mg	ORAL	OTC monograph final	15 sections
PHAZYME	HUMAN OTC DRUG LABEL	1	0132-0208	CAPSULE, GELATIN COATED	180 mg	ORAL	OTC MONOGRAPH FINAL	12 sections
PHAZYME	HUMAN OTC DRUG LABEL	1	0132-0210	CAPSULE, GELATIN COATED	180 mg	ORAL	export only	10 sections
PHAZYME	HUMAN OTC DRUG LABEL	1	0132-0211	CAPSULE, GELATIN COATED	250 mg	ORAL	OTC MONOGRAPH FINAL	12 sections
PHAZYME	HUMAN OTC DRUG LABEL	1	0132-0214	CAPSULE, GELATIN COATED	250 mg	ORAL	OTC MONOGRAPH FINAL	11 sections
PHAZYME	HUMAN OTC DRUG LABEL	1	0132-0215	CAPSULE, GELATIN COATED	250 mg	ORAL	OTC MONOGRAPH FINAL	11 sections
PHAZYME ULTIMATE	HUMAN OTC DRUG LABEL	1	0132-0217	CAPSULE, LIQUID FILLED	500 mg	ORAL	OTC MONOGRAPH FINAL	12 sections
Boudreauxs Butt Barrier	HUMAN OTC DRUG LABEL	1	0132-0326	OINTMENT	1 g	TOPICAL	OTC monograph final	13 sections