dihydroemetine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3129 4914-30-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dehydroemetine
  • mebadin
  • dihydroemetine
was MH 1991-94 (see under EMETINE 1976-90); use EMETINE to search DEHYDROEMETINE 1976-94; amebicide, derivative of emetine
  • Molecular weight: 478.63
  • Formula: C29H38N2O4
  • CLOGP: 4.46
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 1
  • TPSA: 52.19
  • ALOGS: -4.79
  • ROTB: 7

Drug dosage:

DoseUnitRoute
60 mg P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC P01AX09 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
Other agents against amoebiasis and other protozoal diseases
CHEBI has role CHEBI:35820 antiprotozoal drugs
CHEBI has role CHEBI:38068 antimalarials
CHEBI has role CHEBI:70868 antileishmanial drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.61 Basic
pKa2 8.48 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D00828 KEGG_DRUG
CHEBI:149634 CHEBI
CHEMBL547470 ChEMBL_ID
CHEMBL1697741 ChEMBL_ID
C086742 MESH_SUPPLEMENTAL_RECORD_UI
21022 PUBCHEM_CID
DB13865 DRUGBANK_ID
3142 RXNORM
006030 NDDF
C0082286 UMLSCUI
1796 INN_ID
7S79QT1T91 UNII

Pharmaceutical products:

None