clorindione 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3111 1146-99-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • chlorphenylindandione
  • chlorphenindone
  • clorindione
  • chlophenadione
  • chlorathrombon
  • chlorindion
  • chlorindione
  • chlorphenadione
  • chlorphenindione
  • Molecular weight: 256.69
  • Formula: C15H9ClO2
  • CLOGP: 3.52
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 0
  • TPSA: 34.14
  • ALOGS: -4.68
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC B01AA09 BLOOD AND BLOOD FORMING ORGANS
ANTITHROMBOTIC AGENTS
ANTITHROMBOTIC AGENTS
Vitamin K antagonists

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.36 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Arachidonate 5-lipoxygenase Enzyme IC50 5.30 CHEMBL

External reference:

IDSource
D07135 KEGG_DRUG
C0055939 UMLSCUI
CHEBI:135057 CHEBI
CHEMBL278519 ChEMBL_ID
DB13275 DRUGBANK_ID
C004665 MESH_SUPPLEMENTAL_RECORD_UI
70846 PUBCHEM_CID
1534 INN_ID
541C7WS64R UNII
402527 RXNORM
002092 NDDF

Pharmaceutical products:

None