Stem definition | Drug id | CAS RN |
---|---|---|
2847 | 81-81-2 |
Dose | Unit | Route |
---|---|---|
7.50 | mg | O |
7.50 | mg | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.02 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 1 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 0.54 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 93 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 0.13 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 0.06 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.02 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 29 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
June 8, 1954 | FDA | BRISTOL MYERS SQUIBB |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
International normalised ratio increased | 8844.96 | 10.40 | 3811 | 193470 | 42614 | 63249127 |
Drug interaction | 1322.35 | 10.40 | 2470 | 194811 | 226661 | 63065080 |
Calciphylaxis | 1044.61 | 10.40 | 384 | 196897 | 2688 | 63289053 |
International normalised ratio decreased | 899.05 | 10.40 | 383 | 196898 | 4118 | 63287623 |
International normalised ratio abnormal | 892.19 | 10.40 | 349 | 196932 | 2955 | 63288786 |
Pulmonary arterial hypertension | 888.21 | 10.40 | 659 | 196622 | 21918 | 63269823 |
Drug ineffective | 870.97 | 10.40 | 1192 | 196089 | 1043573 | 62248168 |
Dyspnoea | 654.77 | 10.40 | 3888 | 193393 | 657425 | 62634316 |
Gastrointestinal haemorrhage | 615.90 | 10.40 | 989 | 196292 | 80187 | 63211554 |
Fluid retention | 600.33 | 10.40 | 830 | 196451 | 58856 | 63232885 |
Anticoagulation drug level above therapeutic | 584.32 | 10.40 | 205 | 197076 | 1230 | 63290511 |
International normalised ratio fluctuation | 538.80 | 10.40 | 224 | 197057 | 2254 | 63289487 |
Synovitis | 531.02 | 10.40 | 10 | 197271 | 186908 | 63104833 |
Haematoma | 526.33 | 10.40 | 594 | 196687 | 34226 | 63257515 |
Haemorrhage | 519.33 | 10.40 | 784 | 196497 | 60238 | 63231503 |
Cardiac failure congestive | 484.37 | 10.40 | 958 | 196323 | 91475 | 63200266 |
Subdural haematoma | 471.04 | 10.40 | 376 | 196905 | 13952 | 63277789 |
Epistaxis | 452.16 | 10.40 | 811 | 196470 | 71914 | 63219827 |
Atrial fibrillation | 450.99 | 10.40 | 1069 | 196212 | 115567 | 63176174 |
Drug intolerance | 447.04 | 10.40 | 200 | 197081 | 308461 | 62983280 |
Pulmonary hypertension | 442.20 | 10.40 | 561 | 196720 | 36562 | 63255179 |
Contraindicated product administered | 437.29 | 10.40 | 75 | 197206 | 217573 | 63074168 |
Glossodynia | 424.74 | 10.40 | 35 | 197246 | 178841 | 63112900 |
Pain in jaw | 418.12 | 10.40 | 592 | 196689 | 42904 | 63248837 |
Treatment failure | 405.58 | 10.40 | 66 | 197215 | 198977 | 63092764 |
Infusion related reaction | 402.11 | 10.40 | 131 | 197150 | 245390 | 63046351 |
Right ventricular failure | 392.08 | 10.40 | 366 | 196915 | 16822 | 63274919 |
Labelled drug-drug interaction medication error | 390.86 | 10.40 | 328 | 196953 | 13071 | 63278670 |
Hypervolaemia | 382.98 | 10.40 | 457 | 196824 | 27956 | 63263785 |
Hand deformity | 379.11 | 10.40 | 31 | 197250 | 159426 | 63132315 |
Cerebral haemorrhage | 368.54 | 10.40 | 466 | 196815 | 30263 | 63261478 |
Alopecia | 366.06 | 10.40 | 307 | 196974 | 337229 | 62954512 |
Catheter site erythema | 361.12 | 10.40 | 202 | 197079 | 4074 | 63287667 |
Joint swelling | 360.30 | 10.40 | 294 | 196987 | 327372 | 62964369 |
Arthropathy | 349.55 | 10.40 | 146 | 197135 | 234646 | 63057095 |
Melaena | 341.42 | 10.40 | 446 | 196835 | 29919 | 63261822 |
Rheumatoid arthritis | 339.29 | 10.40 | 183 | 197098 | 253636 | 63038105 |
Dyspnoea exertional | 332.81 | 10.40 | 639 | 196642 | 59663 | 63232078 |
Therapeutic product effect decreased | 332.66 | 10.40 | 94 | 197187 | 193093 | 63098648 |
Prothrombin time prolonged | 331.60 | 10.40 | 259 | 197022 | 9305 | 63282436 |
Cardiac failure | 327.25 | 10.40 | 801 | 196480 | 88341 | 63203400 |
Off label use | 326.38 | 10.40 | 1045 | 196236 | 673417 | 62618324 |
Haemoglobin decreased | 315.37 | 10.40 | 1082 | 196199 | 144403 | 63147338 |
Device related infection | 308.29 | 10.40 | 372 | 196909 | 23020 | 63268721 |
Systemic lupus erythematosus | 302.84 | 10.40 | 135 | 197146 | 208783 | 63082958 |
Catheter site pain | 288.05 | 10.40 | 181 | 197100 | 4554 | 63287187 |
Coagulopathy | 286.05 | 10.40 | 336 | 196945 | 20208 | 63271533 |
Pericarditis | 271.62 | 10.40 | 42 | 197239 | 131537 | 63160204 |
Anaemia | 267.44 | 10.40 | 1692 | 195589 | 291738 | 63000003 |
Abdominal wall haematoma | 265.31 | 10.40 | 147 | 197134 | 2908 | 63288833 |
Arthralgia | 258.62 | 10.40 | 907 | 196374 | 568803 | 62722938 |
Hepatic enzyme increased | 254.44 | 10.40 | 157 | 197124 | 202171 | 63089570 |
Catheter management | 251.95 | 10.40 | 141 | 197140 | 2846 | 63288895 |
Hypersensitivity | 251.93 | 10.40 | 324 | 196957 | 292361 | 62999380 |
Drug hypersensitivity | 245.33 | 10.40 | 366 | 196915 | 310321 | 62981420 |
Transfusion | 244.34 | 10.40 | 268 | 197013 | 14949 | 63276792 |
Wound | 243.72 | 10.40 | 101 | 197180 | 163162 | 63128579 |
Discomfort | 242.76 | 10.40 | 108 | 197173 | 167266 | 63124475 |
Musculoskeletal stiffness | 242.40 | 10.40 | 136 | 197145 | 184482 | 63107259 |
Duodenal ulcer perforation | 242.30 | 10.40 | 6 | 197275 | 87203 | 63204538 |
Anticoagulation drug level below therapeutic | 241.08 | 10.40 | 89 | 197192 | 631 | 63291110 |
Rectal haemorrhage | 240.94 | 10.40 | 495 | 196786 | 48535 | 63243206 |
Helicobacter infection | 238.36 | 10.40 | 12 | 197269 | 92773 | 63198968 |
Syncope | 234.47 | 10.40 | 850 | 196431 | 116535 | 63175206 |
Thrombosis | 233.48 | 10.40 | 578 | 196703 | 64177 | 63227564 |
Haemorrhage intracranial | 232.43 | 10.40 | 246 | 197035 | 13173 | 63278568 |
Hypotension | 224.64 | 10.40 | 1533 | 195748 | 271071 | 63020670 |
Oedema peripheral | 224.38 | 10.40 | 1172 | 196109 | 188339 | 63103402 |
Haemoptysis | 209.51 | 10.40 | 344 | 196937 | 28382 | 63263359 |
Haematuria | 205.72 | 10.40 | 344 | 196937 | 28813 | 63262928 |
Catheter site discharge | 203.10 | 10.40 | 107 | 197174 | 1906 | 63289835 |
Rash | 201.85 | 10.40 | 977 | 196304 | 559894 | 62731847 |
Death | 201.77 | 10.40 | 1910 | 195371 | 372471 | 62919270 |
Psoriatic arthropathy | 201.22 | 10.40 | 24 | 197257 | 91496 | 63200245 |
Catheter site pruritus | 197.89 | 10.40 | 107 | 197174 | 2013 | 63289728 |
Pain | 196.74 | 10.40 | 1422 | 195859 | 739206 | 62552535 |
Catheter site infection | 192.20 | 10.40 | 143 | 197138 | 4771 | 63286970 |
Product use issue | 191.85 | 10.40 | 242 | 197039 | 220278 | 63071463 |
Folliculitis | 191.04 | 10.40 | 6 | 197275 | 70311 | 63221430 |
Stomatitis | 178.04 | 10.40 | 105 | 197176 | 138620 | 63153121 |
Muscle haemorrhage | 177.19 | 10.40 | 115 | 197166 | 3064 | 63288677 |
Central venous catheterisation | 172.43 | 10.40 | 105 | 197176 | 2494 | 63289247 |
Catheter site haemorrhage | 169.99 | 10.40 | 112 | 197169 | 3063 | 63288678 |
Muscle injury | 166.10 | 10.40 | 9 | 197272 | 65336 | 63226405 |
Irritable bowel syndrome | 164.04 | 10.40 | 29 | 197252 | 82383 | 63209358 |
Ecchymosis | 160.37 | 10.40 | 185 | 197096 | 10909 | 63280832 |
Infusion site pain | 156.75 | 10.40 | 226 | 197055 | 16643 | 63275098 |
Therapeutic product effect incomplete | 154.43 | 10.40 | 99 | 197182 | 124957 | 63166784 |
Device leakage | 152.07 | 10.40 | 146 | 197135 | 6950 | 63284791 |
Hospitalisation | 150.69 | 10.40 | 593 | 196688 | 84488 | 63207253 |
Heparin-induced thrombocytopenia | 147.93 | 10.40 | 119 | 197162 | 4463 | 63287278 |
Device alarm issue | 144.99 | 10.40 | 78 | 197203 | 1452 | 63290289 |
Blood cholesterol increased | 143.82 | 10.40 | 56 | 197225 | 93976 | 63197765 |
Abdominal discomfort | 140.46 | 10.40 | 518 | 196763 | 320367 | 62971374 |
Sleep disorder due to general medical condition, insomnia type | 139.92 | 10.40 | 5 | 197276 | 52212 | 63239529 |
Catheter site swelling | 138.75 | 10.40 | 75 | 197206 | 1410 | 63290331 |
Maternal exposure during pregnancy | 138.67 | 10.40 | 298 | 196983 | 219764 | 63071977 |
Exposure during pregnancy | 138.05 | 10.40 | 168 | 197113 | 155379 | 63136362 |
Deep vein thrombosis | 137.20 | 10.40 | 570 | 196711 | 83230 | 63208511 |
Catheter placement | 135.65 | 10.40 | 86 | 197195 | 2198 | 63289543 |
Palpitations | 135.10 | 10.40 | 700 | 196581 | 112070 | 63179671 |
Fall | 135.04 | 10.40 | 1834 | 195447 | 390500 | 62901241 |
Flushing | 131.88 | 10.40 | 522 | 196759 | 74565 | 63217176 |
Pulmonary embolism | 131.38 | 10.40 | 712 | 196569 | 115972 | 63175769 |
Oxygen saturation decreased | 130.78 | 10.40 | 584 | 196697 | 88001 | 63203740 |
Product use in unapproved indication | 128.91 | 10.40 | 224 | 197057 | 178856 | 63112885 |
Oedema | 128.24 | 10.40 | 622 | 196659 | 97000 | 63194741 |
Retroperitoneal haematoma | 125.79 | 10.40 | 90 | 197191 | 2823 | 63288918 |
Prothrombin time abnormal | 124.84 | 10.40 | 50 | 197231 | 453 | 63291288 |
Subdural haemorrhage | 124.78 | 10.40 | 92 | 197189 | 3026 | 63288715 |
Coagulation time prolonged | 123.89 | 10.40 | 69 | 197212 | 1379 | 63290362 |
Febrile neutropenia | 122.97 | 10.40 | 112 | 197169 | 118337 | 63173404 |
Blister | 120.79 | 10.40 | 135 | 197146 | 129679 | 63162062 |
Infusion site infection | 117.80 | 10.40 | 72 | 197209 | 1722 | 63290019 |
Chest pain | 116.15 | 10.40 | 1102 | 196179 | 214857 | 63076884 |
Sinusitis | 113.41 | 10.40 | 345 | 196936 | 226308 | 63065433 |
Thrombosis in device | 112.46 | 10.40 | 85 | 197196 | 2905 | 63288836 |
Impaired healing | 110.01 | 10.40 | 94 | 197187 | 102448 | 63189293 |
Bradycardia | 109.01 | 10.40 | 484 | 196797 | 72743 | 63218998 |
Pneumonia aspiration | 108.67 | 10.40 | 293 | 196988 | 34247 | 63257494 |
Type 2 diabetes mellitus | 108.13 | 10.40 | 32 | 197249 | 63836 | 63227905 |
Swelling | 106.27 | 10.40 | 467 | 196814 | 274911 | 63016830 |
Ill-defined disorder | 104.69 | 10.40 | 62 | 197219 | 81693 | 63210048 |
Upper gastrointestinal haemorrhage | 104.22 | 10.40 | 200 | 197081 | 18652 | 63273089 |
Lower respiratory tract infection | 104.12 | 10.40 | 156 | 197125 | 132151 | 63159590 |
Cerebrovascular accident | 102.54 | 10.40 | 630 | 196651 | 107394 | 63184347 |
Cardiac pacemaker insertion | 102.14 | 10.40 | 92 | 197189 | 4034 | 63287707 |
Hypertension | 99.87 | 10.40 | 487 | 196794 | 278816 | 63012925 |
Retroperitoneal haemorrhage | 99.68 | 10.40 | 77 | 197204 | 2720 | 63289021 |
General physical health deterioration | 98.30 | 10.40 | 310 | 196971 | 201092 | 63090649 |
Blood pressure decreased | 97.71 | 10.40 | 431 | 196850 | 64591 | 63227150 |
Skin necrosis | 97.61 | 10.40 | 164 | 197117 | 13786 | 63277955 |
Infection | 97.56 | 10.40 | 374 | 196907 | 228799 | 63062942 |
Pulmonary oedema | 96.76 | 10.40 | 382 | 196899 | 54491 | 63237250 |
Nasal congestion | 96.23 | 10.40 | 432 | 196849 | 65228 | 63226513 |
Catheter site inflammation | 95.73 | 10.40 | 49 | 197232 | 820 | 63290921 |
Fibromyalgia | 94.78 | 10.40 | 67 | 197214 | 80353 | 63211388 |
Lung transplant | 94.17 | 10.40 | 78 | 197203 | 3050 | 63288691 |
Presyncope | 91.77 | 10.40 | 240 | 197041 | 27545 | 63264196 |
Atrial flutter | 89.44 | 10.40 | 130 | 197151 | 9642 | 63282099 |
Infusion site erythema | 89.41 | 10.40 | 143 | 197138 | 11536 | 63280205 |
Haemorrhage subcutaneous | 89.01 | 10.40 | 74 | 197207 | 2909 | 63288832 |
Cardiac valve replacement complication | 85.89 | 10.40 | 28 | 197253 | 129 | 63291612 |
Pneumonia | 85.34 | 10.40 | 1937 | 195344 | 454830 | 62836911 |
Liver injury | 84.66 | 10.40 | 41 | 197240 | 60479 | 63231262 |
Mobility decreased | 84.05 | 10.40 | 155 | 197126 | 121004 | 63170737 |
Device occlusion | 83.78 | 10.40 | 109 | 197172 | 7278 | 63284463 |
Sleep disorder | 83.61 | 10.40 | 78 | 197203 | 81488 | 63210253 |
Psoriasis | 83.57 | 10.40 | 88 | 197193 | 86869 | 63204872 |
Osteoarthritis | 82.44 | 10.40 | 105 | 197176 | 95238 | 63196503 |
Haematemesis | 82.01 | 10.40 | 244 | 197037 | 30168 | 63261573 |
Injection site pain | 81.51 | 10.40 | 176 | 197105 | 129624 | 63162117 |
Pulmonary arterial pressure increased | 80.91 | 10.40 | 76 | 197205 | 3519 | 63288222 |
Faeces discoloured | 80.65 | 10.40 | 178 | 197103 | 18331 | 63273410 |
Catheter site rash | 80.58 | 10.40 | 42 | 197239 | 731 | 63291010 |
Cardiac disorder | 80.30 | 10.40 | 342 | 196939 | 50474 | 63241267 |
Dialysis | 80.28 | 10.40 | 128 | 197153 | 10299 | 63281442 |
Gastrointestinal disorder | 79.91 | 10.40 | 181 | 197100 | 131058 | 63160683 |
Paraesthesia | 79.85 | 10.40 | 237 | 197044 | 156729 | 63135012 |
Injection site reaction | 79.83 | 10.40 | 41 | 197240 | 58483 | 63233258 |
Dizziness | 78.67 | 10.40 | 1818 | 195463 | 428107 | 62863634 |
Shock haemorrhagic | 78.30 | 10.40 | 123 | 197158 | 9772 | 63281969 |
Acute kidney injury | 77.99 | 10.40 | 1200 | 196081 | 262215 | 63029526 |
Malignant neoplasm progression | 77.92 | 10.40 | 84 | 197197 | 82037 | 63209704 |
Catheterisation cardiac | 77.26 | 10.40 | 83 | 197198 | 4520 | 63287221 |
Urticaria | 76.88 | 10.40 | 261 | 197020 | 165541 | 63126200 |
Intra-abdominal haematoma | 76.18 | 10.40 | 55 | 197226 | 1750 | 63289991 |
Complication associated with device | 75.93 | 10.40 | 165 | 197116 | 16813 | 63274928 |
Subarachnoid haemorrhage | 75.87 | 10.40 | 149 | 197132 | 14134 | 63277607 |
Pulmonary thrombosis | 75.66 | 10.40 | 113 | 197168 | 8589 | 63283152 |
Lower gastrointestinal haemorrhage | 75.20 | 10.40 | 107 | 197174 | 7783 | 63283958 |
Haemorrhagic stroke | 74.49 | 10.40 | 91 | 197190 | 5701 | 63286040 |
Loss of personal independence in daily activities | 74.33 | 10.40 | 117 | 197164 | 97173 | 63194568 |
Neutropenia | 74.19 | 10.40 | 286 | 196995 | 174719 | 63117022 |
Blood loss anaemia | 74.17 | 10.40 | 114 | 197167 | 8887 | 63282854 |
Vascular device infection | 73.91 | 10.40 | 102 | 197179 | 7210 | 63284531 |
Coagulation test abnormal | 73.71 | 10.40 | 40 | 197241 | 758 | 63290983 |
Pruritus | 73.51 | 10.40 | 743 | 196538 | 360710 | 62931031 |
C-reactive protein increased | 73.21 | 10.40 | 113 | 197168 | 94594 | 63197147 |
Haemarthrosis | 71.47 | 10.40 | 67 | 197214 | 3094 | 63288647 |
Intentional overdose | 71.30 | 10.40 | 75 | 197206 | 74077 | 63217664 |
Asthenia | 69.48 | 10.40 | 1620 | 195661 | 381984 | 62909757 |
Spinal epidural haematoma | 68.35 | 10.40 | 43 | 197238 | 1084 | 63290657 |
Activated partial thromboplastin time prolonged | 67.95 | 10.40 | 95 | 197186 | 6798 | 63284943 |
Depression | 67.67 | 10.40 | 347 | 196934 | 196145 | 63095596 |
Device related sepsis | 67.27 | 10.40 | 73 | 197208 | 4021 | 63287720 |
Drug abuse | 66.79 | 10.40 | 76 | 197205 | 72442 | 63219299 |
Internal haemorrhage | 66.18 | 10.40 | 81 | 197200 | 5084 | 63286657 |
Therapy change | 64.75 | 10.40 | 87 | 197194 | 5994 | 63285747 |
Cardioactive drug level increased | 64.45 | 10.40 | 54 | 197227 | 2146 | 63289595 |
Device expulsion | 63.85 | 10.40 | 15 | 197266 | 34907 | 63256834 |
Suicidal ideation | 63.61 | 10.40 | 60 | 197221 | 62361 | 63229380 |
Intra-abdominal haemorrhage | 62.99 | 10.40 | 56 | 197225 | 2413 | 63289328 |
Anaphylactic reaction | 62.27 | 10.40 | 68 | 197213 | 66032 | 63225709 |
Hypoaesthesia | 61.06 | 10.40 | 292 | 196989 | 168101 | 63123640 |
Inflammation | 60.91 | 10.40 | 101 | 197180 | 82172 | 63209569 |
Hypocoagulable state | 60.81 | 10.40 | 41 | 197240 | 1166 | 63290575 |
Subcutaneous haematoma | 60.58 | 10.40 | 47 | 197234 | 1671 | 63290070 |
Therapeutic response decreased | 60.54 | 10.40 | 61 | 197220 | 61464 | 63230277 |
Cardiac operation | 59.86 | 10.40 | 62 | 197219 | 3236 | 63288505 |
Injection site erythema | 59.84 | 10.40 | 104 | 197177 | 83070 | 63208671 |
Red blood cell sedimentation rate increased | 59.70 | 10.40 | 31 | 197250 | 43951 | 63247790 |
Spontaneous haematoma | 59.04 | 10.40 | 36 | 197245 | 857 | 63290884 |
Intentional product use issue | 58.81 | 10.40 | 202 | 197079 | 127690 | 63164051 |
Multiple sclerosis relapse | 57.63 | 10.40 | 40 | 197241 | 48438 | 63243303 |
Device infusion issue | 57.60 | 10.40 | 49 | 197232 | 1989 | 63289752 |
Dermatitis contact | 57.46 | 10.40 | 114 | 197167 | 10894 | 63280847 |
Pulmonary endarterectomy | 56.58 | 10.40 | 20 | 197261 | 123 | 63291618 |
Prosthetic cardiac valve thrombosis | 56.30 | 10.40 | 15 | 197266 | 27 | 63291714 |
Leukopenia | 56.19 | 10.40 | 96 | 197185 | 77194 | 63214547 |
Cardiac ablation | 55.38 | 10.40 | 42 | 197239 | 1443 | 63290298 |
Asthma | 54.99 | 10.40 | 207 | 197074 | 127354 | 63164387 |
Gout | 54.88 | 10.40 | 125 | 197156 | 13146 | 63278595 |
COVID-19 | 54.50 | 10.40 | 175 | 197106 | 112928 | 63178813 |
Acute respiratory failure | 54.40 | 10.40 | 232 | 197049 | 34253 | 63257488 |
Head injury | 54.29 | 10.40 | 198 | 197083 | 27198 | 63264543 |
Hypercoagulation | 52.62 | 10.40 | 47 | 197234 | 2038 | 63289703 |
Malaise | 52.61 | 10.40 | 1677 | 195604 | 414277 | 62877464 |
Haemoperitoneum | 52.42 | 10.40 | 53 | 197228 | 2688 | 63289053 |
Torsade de pointes | 52.18 | 10.40 | 123 | 197158 | 13228 | 63278513 |
Pericardial haemorrhage | 52.16 | 10.40 | 42 | 197239 | 1577 | 63290164 |
Catheter site irritation | 52.01 | 10.40 | 28 | 197253 | 522 | 63291219 |
Vascular pseudoaneurysm | 52.00 | 10.40 | 41 | 197240 | 1493 | 63290248 |
Intraventricular haemorrhage | 51.95 | 10.40 | 47 | 197234 | 2073 | 63289668 |
Transplant evaluation | 51.72 | 10.40 | 37 | 197244 | 1160 | 63290581 |
Mucosal inflammation | 51.57 | 10.40 | 42 | 197239 | 46886 | 63244855 |
Gingival bleeding | 51.43 | 10.40 | 118 | 197163 | 12469 | 63279272 |
Gastric haemorrhage | 51.27 | 10.40 | 80 | 197201 | 6318 | 63285423 |
Haematoma muscle | 51.11 | 10.40 | 36 | 197245 | 1101 | 63290640 |
Cellulitis | 51.04 | 10.40 | 432 | 196849 | 81526 | 63210215 |
Food interaction | 50.89 | 10.40 | 32 | 197249 | 806 | 63290935 |
Completed suicide | 50.85 | 10.40 | 256 | 197025 | 145417 | 63146324 |
Bursitis | 50.44 | 10.40 | 26 | 197255 | 37015 | 63254726 |
Renal failure | 50.19 | 10.40 | 573 | 196708 | 117079 | 63174662 |
Myelosuppression | 50.19 | 10.40 | 7 | 197274 | 23696 | 63268045 |
Oxygen consumption increased | 49.91 | 10.40 | 61 | 197220 | 3823 | 63287918 |
Knee arthroplasty | 49.71 | 10.40 | 57 | 197224 | 54149 | 63237592 |
Post procedural haemorrhage | 49.67 | 10.40 | 89 | 197192 | 7875 | 63283866 |
Catheter site related reaction | 49.46 | 10.40 | 33 | 197248 | 922 | 63290819 |
Hypoxia | 48.92 | 10.40 | 336 | 196945 | 59456 | 63232285 |
Hip arthroplasty | 48.31 | 10.40 | 46 | 197235 | 47600 | 63244141 |
Prothrombin time ratio increased | 48.03 | 10.40 | 17 | 197264 | 105 | 63291636 |
Fatigue | 47.83 | 10.40 | 2265 | 195016 | 885763 | 62405978 |
Haematocrit decreased | 47.62 | 10.40 | 245 | 197036 | 39095 | 63252646 |
Injection site pruritus | 47.59 | 10.40 | 42 | 197239 | 45074 | 63246667 |
Potentiating drug interaction | 47.42 | 10.40 | 63 | 197218 | 4293 | 63287448 |
Brain natriuretic peptide increased | 47.20 | 10.40 | 69 | 197212 | 5144 | 63286597 |
Injury | 47.07 | 10.40 | 98 | 197183 | 73149 | 63218592 |
Prescribed overdose | 46.46 | 10.40 | 24 | 197257 | 34129 | 63257612 |
Choroidal haemorrhage | 46.42 | 10.40 | 14 | 197267 | 47 | 63291694 |
Medical device change | 46.41 | 10.40 | 22 | 197259 | 309 | 63291432 |
Infusion site discharge | 46.02 | 10.40 | 28 | 197253 | 664 | 63291077 |
Unevaluable event | 45.19 | 10.40 | 294 | 196987 | 51092 | 63240649 |
Hyperkalaemia | 45.18 | 10.40 | 306 | 196975 | 53897 | 63237844 |
Injection site swelling | 44.74 | 10.40 | 49 | 197232 | 47523 | 63244218 |
Cerebellar haemorrhage | 44.57 | 10.40 | 36 | 197245 | 1358 | 63290383 |
Pelvic haematoma | 44.02 | 10.40 | 26 | 197255 | 583 | 63291158 |
Pleural effusion | 43.44 | 10.40 | 462 | 196819 | 92748 | 63198993 |
Cardioversion | 43.41 | 10.40 | 34 | 197247 | 1226 | 63290515 |
Dyspnoea at rest | 42.89 | 10.40 | 58 | 197223 | 4021 | 63287720 |
Ventricular tachycardia | 42.68 | 10.40 | 148 | 197133 | 19831 | 63271910 |
Muscle spasticity | 42.64 | 10.40 | 8 | 197273 | 21786 | 63269955 |
Traumatic haematoma | 42.57 | 10.40 | 36 | 197245 | 1449 | 63290292 |
Congestive hepatopathy | 42.42 | 10.40 | 49 | 197232 | 2893 | 63288848 |
Cardiac failure chronic | 42.23 | 10.40 | 60 | 197221 | 4358 | 63287383 |
Catheter removal | 41.95 | 10.40 | 22 | 197259 | 388 | 63291353 |
Foot deformity | 41.89 | 10.40 | 17 | 197264 | 27836 | 63263905 |
Respiratory failure | 41.62 | 10.40 | 492 | 196789 | 101366 | 63190375 |
Dehydration | 41.09 | 10.40 | 762 | 196519 | 172592 | 63119149 |
Ischaemic stroke | 40.98 | 10.40 | 136 | 197145 | 17821 | 63273920 |
Catheter site discolouration | 40.79 | 10.40 | 15 | 197266 | 105 | 63291636 |
Anticoagulation drug level decreased | 40.56 | 10.40 | 12 | 197269 | 37 | 63291704 |
Anticoagulation drug level abnormal | 40.41 | 10.40 | 9 | 197272 | 3 | 63291738 |
Prescribed underdose | 40.19 | 10.40 | 21 | 197260 | 29668 | 63262073 |
Occult blood positive | 39.83 | 10.40 | 53 | 197228 | 3617 | 63288124 |
Arrhythmia | 39.73 | 10.40 | 228 | 197053 | 37912 | 63253829 |
Heart valve replacement | 39.45 | 10.40 | 24 | 197257 | 569 | 63291172 |
Heart rate increased | 39.31 | 10.40 | 457 | 196824 | 93781 | 63197960 |
Emergency care | 39.22 | 10.40 | 30 | 197251 | 1044 | 63290697 |
Embolism | 39.03 | 10.40 | 80 | 197201 | 7826 | 63283915 |
Cardiac failure acute | 38.60 | 10.40 | 89 | 197192 | 9434 | 63282307 |
International normalised ratio | 38.57 | 10.40 | 14 | 197267 | 94 | 63291647 |
Brain herniation | 38.23 | 10.40 | 52 | 197229 | 3625 | 63288116 |
Foetal warfarin syndrome | 38.22 | 10.40 | 8 | 197273 | 0 | 63291741 |
Atrial tachycardia | 38.21 | 10.40 | 56 | 197225 | 4184 | 63287557 |
Protein C decreased | 37.91 | 10.40 | 11 | 197270 | 31 | 63291710 |
Spinal cord haematoma | 37.80 | 10.40 | 16 | 197265 | 169 | 63291572 |
Pericardial effusion | 37.64 | 10.40 | 189 | 197092 | 29869 | 63261872 |
Tongue haematoma | 37.62 | 10.40 | 13 | 197268 | 74 | 63291667 |
Ovarian haemorrhage | 37.06 | 10.40 | 19 | 197262 | 319 | 63291422 |
Pulmonary haemorrhage | 37.04 | 10.40 | 74 | 197207 | 7107 | 63284634 |
Sepsis | 36.96 | 10.40 | 675 | 196606 | 152448 | 63139293 |
Wheezing | 36.87 | 10.40 | 162 | 197119 | 95433 | 63196308 |
Dizziness postural | 36.84 | 10.40 | 75 | 197206 | 7301 | 63284440 |
Antiphospholipid syndrome | 36.80 | 10.40 | 36 | 197245 | 1754 | 63289987 |
Lip dry | 36.75 | 10.40 | 3 | 197278 | 15467 | 63276274 |
Vascular pseudoaneurysm ruptured | 36.68 | 10.40 | 12 | 197269 | 56 | 63291685 |
Ascites | 36.41 | 10.40 | 234 | 197047 | 40494 | 63251247 |
Eye haemorrhage | 36.22 | 10.40 | 81 | 197200 | 8415 | 63283326 |
Intestinal haematoma | 36.11 | 10.40 | 13 | 197268 | 85 | 63291656 |
Drug monitoring procedure not performed | 36.03 | 10.40 | 23 | 197258 | 595 | 63291146 |
Anovulatory cycle | 35.89 | 10.40 | 15 | 197266 | 153 | 63291588 |
Anticoagulation drug level increased | 35.70 | 10.40 | 16 | 197265 | 196 | 63291545 |
Device breakage | 35.39 | 10.40 | 97 | 197184 | 11445 | 63280296 |
Orthopnoea | 35.31 | 10.40 | 67 | 197214 | 6194 | 63285547 |
Infusion site cellulitis | 35.27 | 10.40 | 16 | 197265 | 202 | 63291539 |
Obesity | 35.22 | 10.40 | 25 | 197256 | 29927 | 63261814 |
Drug tolerance decreased | 35.08 | 10.40 | 6 | 197275 | 17467 | 63274274 |
Catheter site warmth | 35.06 | 10.40 | 16 | 197265 | 205 | 63291536 |
Haematoma evacuation | 35.06 | 10.40 | 15 | 197266 | 163 | 63291578 |
Wrong technique in product usage process | 34.75 | 10.40 | 90 | 197191 | 62250 | 63229491 |
Adrenal haemorrhage | 34.69 | 10.40 | 20 | 197261 | 428 | 63291313 |
Oral herpes | 34.48 | 10.40 | 19 | 197262 | 26055 | 63265686 |
Spinal subdural haematoma | 34.37 | 10.40 | 14 | 197267 | 133 | 63291608 |
Mineral supplementation | 34.33 | 10.40 | 24 | 197257 | 725 | 63291016 |
Device connection issue | 34.18 | 10.40 | 23 | 197258 | 652 | 63291089 |
Blood viscosity decreased | 34.04 | 10.40 | 11 | 197270 | 49 | 63291692 |
Intentional self-injury | 33.56 | 10.40 | 19 | 197262 | 25668 | 63266073 |
Pregnancy | 33.49 | 10.40 | 39 | 197242 | 36797 | 63254944 |
Cytokine release syndrome | 33.39 | 10.40 | 3 | 197278 | 14311 | 63277430 |
Heart rate irregular | 33.20 | 10.40 | 148 | 197133 | 22273 | 63269468 |
Blood potassium decreased | 33.10 | 10.40 | 234 | 197047 | 41792 | 63249949 |
Seizure | 32.88 | 10.40 | 259 | 197022 | 132375 | 63159366 |
Prothrombin consumption time prolonged | 32.84 | 10.40 | 10 | 197271 | 35 | 63291706 |
Cough | 32.81 | 10.40 | 1164 | 196117 | 291579 | 63000162 |
Anticoagulant-related nephropathy | 32.70 | 10.40 | 8 | 197273 | 8 | 63291733 |
Oxygen therapy | 32.62 | 10.40 | 37 | 197244 | 2141 | 63289600 |
Cardiac valve disease | 32.46 | 10.40 | 52 | 197229 | 4200 | 63287541 |
Anxiety | 32.43 | 10.40 | 478 | 196803 | 217063 | 63074678 |
Catheter site vesicles | 32.41 | 10.40 | 17 | 197264 | 300 | 63291441 |
Extradural haematoma | 32.39 | 10.40 | 33 | 197248 | 1689 | 63290052 |
Catheter culture positive | 32.25 | 10.40 | 14 | 197267 | 158 | 63291583 |
Rheumatoid nodule | 32.10 | 10.40 | 7 | 197274 | 17148 | 63274593 |
Headache | 31.99 | 10.40 | 2331 | 194950 | 630910 | 62660831 |
Suicide attempt | 31.67 | 10.40 | 91 | 197190 | 60827 | 63230914 |
Sedation | 31.25 | 10.40 | 45 | 197236 | 38764 | 63252977 |
Aortic valve replacement | 31.05 | 10.40 | 23 | 197258 | 762 | 63290979 |
Renal vascular thrombosis | 31.04 | 10.40 | 10 | 197271 | 44 | 63291697 |
Infusion site warmth | 30.90 | 10.40 | 33 | 197248 | 1785 | 63289956 |
Haemothorax | 30.85 | 10.40 | 36 | 197245 | 2149 | 63289592 |
Night sweats | 30.78 | 10.40 | 66 | 197215 | 48748 | 63242993 |
Hypovolaemic shock | 30.63 | 10.40 | 63 | 197218 | 6178 | 63285563 |
Protein S decreased | 30.60 | 10.40 | 9 | 197272 | 27 | 63291714 |
Hypercholesterolaemia | 30.53 | 10.40 | 14 | 197267 | 21320 | 63270421 |
Illness | 30.38 | 10.40 | 67 | 197214 | 48992 | 63242749 |
Central venous catheter removal | 30.30 | 10.40 | 18 | 197263 | 408 | 63291333 |
Neutrophil count decreased | 30.25 | 10.40 | 83 | 197198 | 56323 | 63235418 |
Ear pain | 29.96 | 10.40 | 41 | 197240 | 36077 | 63255664 |
Arthritis | 29.85 | 10.40 | 224 | 197057 | 115697 | 63176044 |
Grip strength decreased | 29.82 | 10.40 | 16 | 197265 | 22271 | 63269470 |
Petechiae | 29.73 | 10.40 | 103 | 197178 | 13794 | 63277947 |
Intracardiac thrombus | 29.60 | 10.40 | 37 | 197244 | 2373 | 63289368 |
Psychotic disorder | 29.53 | 10.40 | 22 | 197259 | 25690 | 63266051 |
Accidental exposure to product | 29.53 | 10.40 | 25 | 197256 | 27380 | 63264361 |
Joint stiffness | 29.52 | 10.40 | 53 | 197228 | 41816 | 63249925 |
Coma | 29.50 | 10.40 | 318 | 196963 | 64046 | 63227695 |
Accidental overdose | 29.49 | 10.40 | 147 | 197134 | 23162 | 63268579 |
Cerebral haematoma | 29.44 | 10.40 | 46 | 197235 | 3637 | 63288104 |
Drug dependence | 29.36 | 10.40 | 20 | 197261 | 24463 | 63267278 |
Mediastinal haematoma | 29.32 | 10.40 | 11 | 197270 | 82 | 63291659 |
Product complaint | 29.22 | 10.40 | 97 | 197184 | 12712 | 63279029 |
Breast haematoma | 29.20 | 10.40 | 14 | 197267 | 202 | 63291539 |
Gangrene | 29.10 | 10.40 | 61 | 197220 | 6062 | 63285679 |
Vaginal haemorrhage | 29.08 | 10.40 | 165 | 197116 | 27322 | 63264419 |
Osteoporosis | 28.83 | 10.40 | 87 | 197194 | 57251 | 63234490 |
Haematochezia | 28.60 | 10.40 | 273 | 197008 | 53271 | 63238470 |
Condition aggravated | 28.57 | 10.40 | 993 | 196288 | 401224 | 62890517 |
Basal cell carcinoma | 28.40 | 10.40 | 27 | 197254 | 27964 | 63263777 |
Acute myeloid leukaemia | 28.28 | 10.40 | 9 | 197272 | 17138 | 63274603 |
Cerebral mass effect | 27.97 | 10.40 | 23 | 197258 | 890 | 63290851 |
Immunodeficiency | 27.90 | 10.40 | 14 | 197267 | 20240 | 63271501 |
Calcium deficiency | 27.89 | 10.40 | 25 | 197256 | 1089 | 63290652 |
Cardiac arrest | 27.86 | 10.40 | 423 | 196858 | 92122 | 63199619 |
Dilatation ventricular | 27.61 | 10.40 | 36 | 197245 | 2409 | 63289332 |
Atrial thrombosis | 27.43 | 10.40 | 31 | 197250 | 1787 | 63289954 |
Myxoedema coma | 27.39 | 10.40 | 17 | 197264 | 418 | 63291323 |
Vitamin K deficiency | 27.22 | 10.40 | 17 | 197264 | 423 | 63291318 |
Sciatic nerve palsy | 27.20 | 10.40 | 8 | 197273 | 24 | 63291717 |
Facet joint syndrome | 27.13 | 10.40 | 3 | 197278 | 12135 | 63279606 |
Lupus-like syndrome | 27.12 | 10.40 | 7 | 197274 | 15288 | 63276453 |
Diarrhoea | 26.99 | 10.40 | 2576 | 194705 | 712790 | 62578951 |
Bradyarrhythmia | 26.83 | 10.40 | 33 | 197248 | 2082 | 63289659 |
Joint range of motion decreased | 26.71 | 10.40 | 37 | 197244 | 32391 | 63259350 |
Intestinal haemorrhage | 26.61 | 10.40 | 45 | 197236 | 3802 | 63287939 |
Abdominal distension | 26.50 | 10.40 | 397 | 196884 | 86218 | 63205523 |
Breast necrosis | 26.35 | 10.40 | 12 | 197269 | 153 | 63291588 |
Colitis | 26.33 | 10.40 | 71 | 197210 | 48457 | 63243284 |
Hepatotoxicity | 26.02 | 10.40 | 47 | 197234 | 36994 | 63254747 |
Infusion site swelling | 25.97 | 10.40 | 78 | 197203 | 9692 | 63282049 |
Haemorrhagic diathesis | 25.84 | 10.40 | 48 | 197233 | 4367 | 63287374 |
Infusion site abscess | 25.81 | 10.40 | 13 | 197268 | 210 | 63291531 |
Drug level changed | 25.81 | 10.40 | 13 | 197268 | 210 | 63291531 |
Lethargy | 25.80 | 10.40 | 277 | 197004 | 55730 | 63236011 |
Infusion site haemorrhage | 25.74 | 10.40 | 52 | 197229 | 5034 | 63286707 |
Mitral valve disease | 25.68 | 10.40 | 35 | 197246 | 2445 | 63289296 |
Pyrexia | 25.58 | 10.40 | 1198 | 196083 | 469280 | 62822461 |
Pancytopenia | 25.58 | 10.40 | 186 | 197095 | 96747 | 63194994 |
Disease complication | 25.54 | 10.40 | 40 | 197241 | 3169 | 63288572 |
Loss of consciousness | 25.51 | 10.40 | 512 | 196769 | 117609 | 63174132 |
Blood viscosity increased | 25.40 | 10.40 | 14 | 197267 | 274 | 63291467 |
Hypoprothrombinaemia | 25.26 | 10.40 | 14 | 197267 | 277 | 63291464 |
Skin weeping | 25.25 | 10.40 | 20 | 197261 | 733 | 63291008 |
Sedation complication | 25.14 | 10.40 | 6 | 197275 | 13816 | 63277925 |
Exostosis | 25.13 | 10.40 | 12 | 197269 | 17850 | 63273891 |
Adverse drug reaction | 25.08 | 10.40 | 145 | 197136 | 79569 | 63212172 |
Hip fracture | 24.92 | 10.40 | 167 | 197114 | 29307 | 63262434 |
Mouth haemorrhage | 24.91 | 10.40 | 61 | 197220 | 6722 | 63285019 |
Neoplasm progression | 24.89 | 10.40 | 47 | 197234 | 36381 | 63255360 |
Compartment syndrome | 24.81 | 10.40 | 33 | 197248 | 2251 | 63289490 |
Cardiomegaly | 24.39 | 10.40 | 114 | 197167 | 17500 | 63274241 |
Atrial septal defect repair | 24.36 | 10.40 | 13 | 197268 | 238 | 63291503 |
Scleroderma | 24.33 | 10.40 | 53 | 197228 | 5409 | 63286332 |
Dry mouth | 24.30 | 10.40 | 142 | 197139 | 77721 | 63214020 |
Application site pruritus | 24.18 | 10.40 | 44 | 197237 | 3940 | 63287801 |
Right ventricular dysfunction | 24.08 | 10.40 | 29 | 197252 | 1790 | 63289951 |
Therapeutic response shortened | 24.05 | 10.40 | 4 | 197277 | 11884 | 63279857 |
Haemorrhagic ovarian cyst | 24.05 | 10.40 | 19 | 197262 | 694 | 63291047 |
Generalised tonic-clonic seizure | 24.00 | 10.40 | 33 | 197248 | 28983 | 63262758 |
Gastric antral vascular ectasia | 23.97 | 10.40 | 18 | 197263 | 609 | 63291132 |
Therapy interrupted | 23.87 | 10.40 | 40 | 197241 | 32415 | 63259326 |
Infusion site irritation | 23.54 | 10.40 | 21 | 197260 | 909 | 63290832 |
Prothrombin time shortened | 23.50 | 10.40 | 30 | 197251 | 1965 | 63289776 |
Endarterectomy | 23.38 | 10.40 | 12 | 197269 | 202 | 63291539 |
Serotonin syndrome | 23.35 | 10.40 | 33 | 197248 | 28649 | 63263092 |
Cardiogenic shock | 23.34 | 10.40 | 114 | 197167 | 17818 | 63273923 |
Thyroid haemorrhage | 23.23 | 10.40 | 9 | 197272 | 74 | 63291667 |
Prothrombin level abnormal | 23.13 | 10.40 | 9 | 197272 | 75 | 63291666 |
Coagulation time shortened | 23.11 | 10.40 | 11 | 197270 | 156 | 63291585 |
Cerebral infarction | 23.06 | 10.40 | 140 | 197141 | 23753 | 63267988 |
Catheter site dermatitis | 23.02 | 10.40 | 9 | 197272 | 76 | 63291665 |
Atrioventricular block complete | 23.00 | 10.40 | 67 | 197214 | 8184 | 63283557 |
Foetal exposure during pregnancy | 22.95 | 10.40 | 40 | 197241 | 31922 | 63259819 |
No adverse event | 22.90 | 10.40 | 60 | 197221 | 41345 | 63250396 |
Sleep disorder due to a general medical condition | 22.75 | 10.40 | 5 | 197276 | 12183 | 63279558 |
Catarrh | 22.67 | 10.40 | 26 | 197255 | 1523 | 63290218 |
Subdural haematoma evacuation | 22.46 | 10.40 | 7 | 197274 | 27 | 63291714 |
Protein S deficiency | 22.46 | 10.40 | 7 | 197274 | 27 | 63291714 |
Palmar-plantar erythrodysaesthesia syndrome | 22.43 | 10.40 | 23 | 197258 | 22992 | 63268749 |
Renal disorder | 22.24 | 10.40 | 177 | 197104 | 32797 | 63258944 |
Pulmonary arterial pressure abnormal | 22.22 | 10.40 | 16 | 197265 | 507 | 63291234 |
Catheter site nodule | 22.00 | 10.40 | 8 | 197273 | 54 | 63291687 |
Skin exfoliation | 21.95 | 10.40 | 65 | 197216 | 43037 | 63248704 |
Concomitant disease progression | 21.92 | 10.40 | 30 | 197251 | 2104 | 63289637 |
Cognitive disorder | 21.88 | 10.40 | 94 | 197187 | 55721 | 63236020 |
Dry eye | 21.84 | 10.40 | 60 | 197221 | 40701 | 63251040 |
Coagulation factor decreased | 21.61 | 10.40 | 9 | 197272 | 91 | 63291650 |
Dizziness exertional | 21.47 | 10.40 | 14 | 197267 | 376 | 63291365 |
Transient ischaemic attack | 21.42 | 10.40 | 195 | 197086 | 37558 | 63254183 |
Sciatica | 21.15 | 10.40 | 47 | 197234 | 34277 | 63257464 |
Tendonitis | 21.00 | 10.40 | 18 | 197263 | 19597 | 63272144 |
Spinal subarachnoid haemorrhage | 20.96 | 10.40 | 5 | 197276 | 4 | 63291737 |
Medical device site thrombosis | 20.96 | 10.40 | 5 | 197276 | 4 | 63291737 |
Walking distance test abnormal | 20.89 | 10.40 | 16 | 197265 | 558 | 63291183 |
Ovarian rupture | 20.85 | 10.40 | 7 | 197274 | 36 | 63291705 |
Deep vein thrombosis postoperative | 20.55 | 10.40 | 5 | 197276 | 11364 | 63280377 |
Neuroleptic malignant syndrome | 20.48 | 10.40 | 6 | 197275 | 12050 | 63279691 |
Gastrointestinal arteriovenous malformation | 20.45 | 10.40 | 16 | 197265 | 576 | 63291165 |
Aortic stenosis | 20.44 | 10.40 | 47 | 197234 | 4973 | 63286768 |
Abdominal wall haemorrhage | 20.39 | 10.40 | 10 | 197271 | 152 | 63291589 |
Dermatitis atopic | 20.29 | 10.40 | 3 | 197278 | 9721 | 63282020 |
Blood culture negative | 20.28 | 10.40 | 10 | 197271 | 154 | 63291587 |
Aphthous ulcer | 20.17 | 10.40 | 9 | 197272 | 13929 | 63277812 |
Tuberculosis | 20.13 | 10.40 | 5 | 197276 | 11206 | 63280535 |
Drug resistance | 20.08 | 10.40 | 25 | 197256 | 22908 | 63268833 |
Cardioactive drug level decreased | 20.02 | 10.40 | 8 | 197273 | 72 | 63291669 |
Oral mucosa haematoma | 19.96 | 10.40 | 5 | 197276 | 6 | 63291735 |
Gait disturbance | 19.80 | 10.40 | 426 | 196855 | 182752 | 63108989 |
Conjunctival haemorrhage | 19.76 | 10.40 | 38 | 197243 | 3549 | 63288192 |
Stent placement | 19.73 | 10.40 | 39 | 197242 | 3716 | 63288025 |
Exercise tolerance decreased | 19.72 | 10.40 | 49 | 197232 | 5448 | 63286293 |
Retching | 19.70 | 10.40 | 94 | 197187 | 14551 | 63277190 |
Drug eruption | 19.63 | 10.40 | 37 | 197244 | 28657 | 63263084 |
Blood pressure increased | 19.58 | 10.40 | 370 | 196911 | 161692 | 63130049 |
Mitral valve repair | 19.57 | 10.40 | 11 | 197270 | 224 | 63291517 |
Heart valve operation | 19.56 | 10.40 | 10 | 197271 | 167 | 63291574 |
Gastrooesophageal reflux disease | 19.48 | 10.40 | 411 | 196870 | 95228 | 63196513 |
Nephrosclerosis | 19.46 | 10.40 | 20 | 197261 | 1034 | 63290707 |
Balloon atrial septostomy | 19.46 | 10.40 | 8 | 197273 | 78 | 63291663 |
Procedural pain | 19.43 | 10.40 | 23 | 197258 | 21546 | 63270195 |
Blood pressure fluctuation | 19.41 | 10.40 | 76 | 197205 | 46241 | 63245500 |
Autoimmune disorder | 19.34 | 10.40 | 15 | 197266 | 17162 | 63274579 |
Endocarditis | 19.32 | 10.40 | 50 | 197231 | 5700 | 63286041 |
Infusion site oedema | 19.20 | 10.40 | 18 | 197263 | 831 | 63290910 |
Tracheal calcification | 19.11 | 10.40 | 4 | 197277 | 0 | 63291741 |
Femoral nerve palsy | 19.11 | 10.40 | 4 | 197277 | 0 | 63291741 |
Valvuloplasty cardiac | 19.11 | 10.40 | 4 | 197277 | 0 | 63291741 |
Device dislocation | 19.02 | 10.40 | 141 | 197140 | 25564 | 63266177 |
Injection site urticaria | 18.98 | 10.40 | 10 | 197271 | 14063 | 63277678 |
Cardiac pacemaker replacement | 18.85 | 10.40 | 13 | 197268 | 384 | 63291357 |
Aortic dissection | 18.69 | 10.40 | 27 | 197254 | 1991 | 63289750 |
Haemophagocytic lymphohistiocytosis | 18.59 | 10.40 | 5 | 197276 | 10622 | 63281119 |
Catheter site oedema | 18.57 | 10.40 | 7 | 197274 | 53 | 63291688 |
Toxicity to various agents | 18.56 | 10.40 | 606 | 196675 | 246644 | 63045097 |
Blue toe syndrome | 18.56 | 10.40 | 13 | 197268 | 394 | 63291347 |
Cardiac flutter | 18.53 | 10.40 | 40 | 197241 | 4056 | 63287685 |
Dystonia | 18.37 | 10.40 | 10 | 197271 | 13809 | 63277932 |
Abdominal cavity drainage | 18.27 | 10.40 | 13 | 197268 | 404 | 63291337 |
Prothrombin level increased | 18.26 | 10.40 | 11 | 197270 | 256 | 63291485 |
Product storage error | 18.23 | 10.40 | 12 | 197269 | 14944 | 63276797 |
Hepatorenal failure | 18.22 | 10.40 | 16 | 197265 | 678 | 63291063 |
Device related thrombosis | 18.19 | 10.40 | 25 | 197256 | 1760 | 63289981 |
Abortion spontaneous | 18.18 | 10.40 | 80 | 197201 | 47115 | 63244626 |
Hepatitis | 18.17 | 10.40 | 63 | 197218 | 39725 | 63252016 |
Sinus node dysfunction | 18.13 | 10.40 | 43 | 197238 | 4642 | 63287099 |
Injection site rash | 18.10 | 10.40 | 19 | 197262 | 18790 | 63272951 |
Joint dislocation | 18.08 | 10.40 | 19 | 197262 | 18781 | 63272960 |
Drain placement | 18.02 | 10.40 | 7 | 197274 | 58 | 63291683 |
Insomnia | 18.01 | 10.40 | 520 | 196761 | 214732 | 63077009 |
Catheter site dryness | 18.01 | 10.40 | 6 | 197275 | 30 | 63291711 |
Multiple sclerosis | 17.96 | 10.40 | 30 | 197251 | 24342 | 63267399 |
Catheter site urticaria | 17.84 | 10.40 | 6 | 197275 | 31 | 63291710 |
Mitral valve replacement | 17.82 | 10.40 | 11 | 197270 | 268 | 63291473 |
Purple glove syndrome | 17.82 | 10.40 | 10 | 197271 | 203 | 63291538 |
Acne | 17.79 | 10.40 | 28 | 197253 | 23265 | 63268476 |
Breast cancer female | 17.75 | 10.40 | 10 | 197271 | 13549 | 63278192 |
Hydrocephalus | 17.72 | 10.40 | 46 | 197235 | 5254 | 63286487 |
Mitral valve stenosis | 17.64 | 10.40 | 20 | 197261 | 1157 | 63290584 |
Liver function test abnormal | 17.63 | 10.40 | 228 | 197053 | 47953 | 63243788 |
Drug ineffective for unapproved indication | 17.62 | 10.40 | 51 | 197230 | 34012 | 63257729 |
Subarachnoid haematoma | 17.52 | 10.40 | 5 | 197276 | 13 | 63291728 |
Blood potassium increased | 17.49 | 10.40 | 107 | 197174 | 18202 | 63273539 |
Injection site warmth | 17.45 | 10.40 | 13 | 197268 | 15182 | 63276559 |
Renal impairment | 17.45 | 10.40 | 378 | 196903 | 87977 | 63203764 |
Eschar | 17.44 | 10.40 | 15 | 197266 | 618 | 63291123 |
Device difficult to use | 17.39 | 10.40 | 9 | 197272 | 12787 | 63278954 |
Lymphocyte count decreased | 17.39 | 10.40 | 43 | 197238 | 30214 | 63261527 |
Contusion | 17.37 | 10.40 | 599 | 196682 | 149445 | 63142296 |
Embolic stroke | 17.23 | 10.40 | 37 | 197244 | 3739 | 63288002 |
Pulmonary alveolar haemorrhage | 17.16 | 10.40 | 42 | 197239 | 4626 | 63287115 |
Cytomegalovirus infection | 17.16 | 10.40 | 24 | 197257 | 20928 | 63270813 |
Thoracic haemorrhage | 17.10 | 10.40 | 6 | 197275 | 36 | 63291705 |
Thrombectomy | 17.10 | 10.40 | 9 | 197272 | 160 | 63291581 |
Panniculitis | 17.04 | 10.40 | 7 | 197274 | 11378 | 63280363 |
Chronic cutaneous lupus erythematosus | 17.01 | 10.40 | 12 | 197269 | 368 | 63291373 |
Nocturnal dyspnoea | 17.00 | 10.40 | 20 | 197261 | 1204 | 63290537 |
Jugular vein distension | 16.94 | 10.40 | 18 | 197263 | 968 | 63290773 |
Cor pulmonale | 16.90 | 10.40 | 26 | 197255 | 2028 | 63289713 |
Injection site discharge | 16.90 | 10.40 | 17 | 197264 | 857 | 63290884 |
Arteriovenous malformation | 16.90 | 10.40 | 21 | 197260 | 1339 | 63290402 |
Heart sounds abnormal | 16.82 | 10.40 | 15 | 197266 | 649 | 63291092 |
Large intestinal polypectomy | 16.78 | 10.40 | 10 | 197271 | 228 | 63291513 |
Skin reaction | 16.68 | 10.40 | 13 | 197268 | 14836 | 63276905 |
Obstructive airways disorder | 16.66 | 10.40 | 24 | 197257 | 20675 | 63271066 |
Exophthalmos | 16.62 | 10.40 | 22 | 197259 | 1494 | 63290247 |
Gestational diabetes | 16.60 | 10.40 | 3 | 197278 | 8393 | 63283348 |
Cerebellar haematoma | 16.59 | 10.40 | 12 | 197269 | 383 | 63291358 |
Hypophagia | 16.50 | 10.40 | 159 | 197122 | 31100 | 63260641 |
Haemorrhagic ascites | 16.41 | 10.40 | 8 | 197273 | 120 | 63291621 |
Pneumocystis jirovecii pneumonia | 16.37 | 10.40 | 17 | 197264 | 16897 | 63274844 |
Coma scale normal | 16.35 | 10.40 | 4 | 197277 | 4 | 63291737 |
Cerebral venous sinus thrombosis | 16.28 | 10.40 | 25 | 197256 | 1947 | 63289794 |
Angiodysplasia | 16.21 | 10.40 | 12 | 197269 | 397 | 63291344 |
Iron deficiency anaemia | 16.20 | 10.40 | 112 | 197169 | 19857 | 63271884 |
Right ventricular enlargement | 16.16 | 10.40 | 11 | 197270 | 318 | 63291423 |
Cholecystitis chronic | 16.12 | 10.40 | 6 | 197275 | 10355 | 63281386 |
Feeling abnormal | 16.09 | 10.40 | 588 | 196693 | 147804 | 63143937 |
Chronic sinusitis | 16.07 | 10.40 | 10 | 197271 | 12833 | 63278908 |
Disability | 16.06 | 10.40 | 20 | 197261 | 18327 | 63273414 |
Coeliac disease | 15.96 | 10.40 | 10 | 197271 | 12787 | 63278954 |
Myocardial infarction | 15.95 | 10.40 | 415 | 196866 | 99478 | 63192263 |
Metastases to lymph nodes | 15.95 | 10.40 | 3 | 197278 | 8155 | 63283586 |
Duodenal ulcer haemorrhage | 15.94 | 10.40 | 28 | 197253 | 2439 | 63289302 |
Carpal tunnel syndrome | 15.92 | 10.40 | 25 | 197256 | 20792 | 63270949 |
Device physical property issue | 15.90 | 10.40 | 25 | 197256 | 1987 | 63289754 |
Mood swings | 15.86 | 10.40 | 20 | 197261 | 18228 | 63273513 |
Blood urea increased | 15.86 | 10.40 | 138 | 197143 | 26241 | 63265500 |
Venous thrombosis | 15.83 | 10.40 | 42 | 197239 | 4860 | 63286881 |
Aplastic anaemia | 15.82 | 10.40 | 5 | 197276 | 9564 | 63282177 |
X-ray abnormal | 15.82 | 10.40 | 3 | 197278 | 8107 | 63283634 |
Heavy menstrual bleeding | 15.81 | 10.40 | 102 | 197179 | 17671 | 63274070 |
Pulmonary calcification | 15.69 | 10.40 | 10 | 197271 | 258 | 63291483 |
Left ventricular failure | 15.68 | 10.40 | 46 | 197235 | 5641 | 63286100 |
Ovarian cyst ruptured | 15.68 | 10.40 | 19 | 197262 | 1180 | 63290561 |
Inappropriate schedule of product administration | 15.63 | 10.40 | 228 | 197053 | 103737 | 63188004 |
Vaginal haematoma | 15.57 | 10.40 | 8 | 197273 | 135 | 63291606 |
Dysentery | 15.55 | 10.40 | 17 | 197264 | 944 | 63290797 |
Catheter site mass | 15.34 | 10.40 | 5 | 197276 | 23 | 63291718 |
Diastolic hypotension | 15.32 | 10.40 | 7 | 197274 | 90 | 63291651 |
Urine output decreased | 15.31 | 10.40 | 73 | 197208 | 11297 | 63280444 |
Overdose | 15.28 | 10.40 | 467 | 196814 | 114611 | 63177130 |
Vascular stenosis | 15.26 | 10.40 | 11 | 197270 | 349 | 63291392 |
Splenic haemorrhage | 15.23 | 10.40 | 9 | 197272 | 202 | 63291539 |
Disturbance in attention | 15.16 | 10.40 | 64 | 197217 | 38125 | 63253616 |
Right ventricular systolic pressure increased | 15.15 | 10.40 | 13 | 197268 | 534 | 63291207 |
Multiple injuries | 15.13 | 10.40 | 23 | 197258 | 1775 | 63289966 |
Haemorrhagic cerebral infarction | 15.13 | 10.40 | 14 | 197267 | 636 | 63291105 |
Chronic respiratory failure | 15.12 | 10.40 | 24 | 197257 | 1923 | 63289818 |
Schizophrenia | 15.09 | 10.40 | 6 | 197275 | 9946 | 63281795 |
Coagulation factor deficiency | 15.08 | 10.40 | 4 | 197277 | 7 | 63291734 |
Parosmia | 15.06 | 10.40 | 48 | 197233 | 6158 | 63285583 |
Colitis ulcerative | 15.05 | 10.40 | 37 | 197244 | 26054 | 63265687 |
Sickle cell anaemia | 15.03 | 10.40 | 13 | 197268 | 540 | 63291201 |
Incorrect route of product administration | 15.02 | 10.40 | 40 | 197241 | 27412 | 63264329 |
Tri-iodothyronine increased | 15.01 | 10.40 | 8 | 197273 | 146 | 63291595 |
Endotracheal intubation | 14.97 | 10.40 | 28 | 197253 | 2560 | 63289181 |
Conjunctivitis | 14.95 | 10.40 | 26 | 197255 | 20770 | 63270971 |
Angioplasty | 14.95 | 10.40 | 20 | 197261 | 1372 | 63290369 |
Hypercalcaemia | 14.94 | 10.40 | 42 | 197239 | 28280 | 63263461 |
Infusion site pruritus | 14.94 | 10.40 | 47 | 197234 | 5988 | 63285753 |
Blood creatinine increased | 14.93 | 10.40 | 368 | 196913 | 87476 | 63204265 |
White blood cell count decreased | 14.88 | 10.40 | 324 | 196957 | 138780 | 63152961 |
Terminal state | 14.87 | 10.40 | 26 | 197255 | 2256 | 63289485 |
Anaphylactic shock | 14.86 | 10.40 | 32 | 197249 | 23601 | 63268140 |
Lacrimal haemorrhage | 14.84 | 10.40 | 5 | 197276 | 26 | 63291715 |
Burns second degree | 14.84 | 10.40 | 24 | 197257 | 1954 | 63289787 |
Hypopnoea | 14.80 | 10.40 | 35 | 197246 | 3771 | 63287970 |
Blood culture positive | 14.72 | 10.40 | 40 | 197241 | 4695 | 63287046 |
Thromboembolectomy | 14.69 | 10.40 | 5 | 197276 | 27 | 63291714 |
Implantable defibrillator insertion | 14.67 | 10.40 | 12 | 197269 | 461 | 63291280 |
Venous pressure jugular increased | 14.55 | 10.40 | 13 | 197268 | 564 | 63291177 |
Mouth ulceration | 14.55 | 10.40 | 53 | 197228 | 32931 | 63258810 |
Periorbital haematoma | 14.54 | 10.40 | 15 | 197266 | 779 | 63290962 |
Joint effusion | 14.52 | 10.40 | 19 | 197262 | 17041 | 63274700 |
Cardiac tamponade | 14.51 | 10.40 | 40 | 197241 | 4735 | 63287006 |
Extrasystoles | 14.48 | 10.40 | 42 | 197239 | 5118 | 63286623 |
Uterine haemorrhage | 14.48 | 10.40 | 36 | 197245 | 4005 | 63287736 |
Stress | 14.48 | 10.40 | 136 | 197145 | 67031 | 63224710 |
Metastases to bone | 14.47 | 10.40 | 27 | 197254 | 20992 | 63270749 |
Occult blood | 14.45 | 10.40 | 19 | 197262 | 1282 | 63290459 |
Diabetic ketoacidosis | 14.42 | 10.40 | 26 | 197255 | 20479 | 63271262 |
Colonoscopy | 14.37 | 10.40 | 21 | 197260 | 1565 | 63290176 |
Hepatic artery embolism | 14.33 | 10.40 | 3 | 197278 | 0 | 63291741 |
Adrenal cortex necrosis | 14.33 | 10.40 | 3 | 197278 | 0 | 63291741 |
Acquired cardiac septal defect | 14.33 | 10.40 | 3 | 197278 | 0 | 63291741 |
Iris haemorrhage | 14.33 | 10.40 | 3 | 197278 | 0 | 63291741 |
Cardiac pacemaker adjustment | 14.33 | 10.40 | 3 | 197278 | 0 | 63291741 |
Productive cough | 14.32 | 10.40 | 276 | 197005 | 62932 | 63228809 |
Squamous cell carcinoma of the oral cavity | 14.31 | 10.40 | 10 | 197271 | 302 | 63291439 |
Blood pressure systolic decreased | 14.27 | 10.40 | 53 | 197228 | 7344 | 63284397 |
Abdominal compartment syndrome | 14.24 | 10.40 | 13 | 197268 | 580 | 63291161 |
Traumatic intracranial haemorrhage | 14.21 | 10.40 | 12 | 197269 | 482 | 63291259 |
Catheter site erosion | 14.20 | 10.40 | 6 | 197275 | 63 | 63291678 |
Application site irritation | 14.19 | 10.40 | 22 | 197259 | 1728 | 63290013 |
Herpes zoster | 14.14 | 10.40 | 176 | 197105 | 82286 | 63209455 |
Oesophageal compression | 14.13 | 10.40 | 4 | 197277 | 10 | 63291731 |
Chordae tendinae rupture | 14.11 | 10.40 | 5 | 197276 | 31 | 63291710 |
Factor V inhibition | 14.01 | 10.40 | 8 | 197273 | 168 | 63291573 |
Rales | 13.95 | 10.40 | 77 | 197204 | 12620 | 63279121 |
Brain operation | 13.95 | 10.40 | 13 | 197268 | 596 | 63291145 |
Therapeutic product effect increased | 13.89 | 10.40 | 18 | 197263 | 1197 | 63290544 |
Prothrombin level decreased | 13.84 | 10.40 | 13 | 197268 | 602 | 63291139 |
Clostridium difficile infection | 13.78 | 10.40 | 148 | 197133 | 29774 | 63261967 |
Progressive multifocal leukoencephalopathy | 13.77 | 10.40 | 12 | 197269 | 12959 | 63278782 |
Lip haemorrhage | 13.72 | 10.40 | 12 | 197269 | 506 | 63291235 |
Central nervous system lesion | 13.70 | 10.40 | 8 | 197273 | 10627 | 63281114 |
Haematotoxicity | 13.66 | 10.40 | 6 | 197275 | 9370 | 63282371 |
Bullous haemorrhagic dermatosis | 13.65 | 10.40 | 6 | 197275 | 70 | 63291671 |
Haemorrhagic hepatic cyst | 13.60 | 10.40 | 5 | 197276 | 35 | 63291706 |
Live birth | 13.53 | 10.40 | 38 | 197243 | 25592 | 63266149 |
Thrombotic microangiopathy | 13.53 | 10.40 | 8 | 197273 | 10553 | 63281188 |
Affect lability | 13.52 | 10.40 | 9 | 197272 | 11142 | 63280599 |
Emergency care examination | 13.42 | 10.40 | 6 | 197275 | 73 | 63291668 |
Oral candidiasis | 13.41 | 10.40 | 32 | 197249 | 22766 | 63268975 |
Intervertebral disc protrusion | 13.39 | 10.40 | 34 | 197247 | 23675 | 63268066 |
Spinal stenosis | 13.35 | 10.40 | 16 | 197265 | 14909 | 63276832 |
Neutropenic sepsis | 13.29 | 10.40 | 19 | 197262 | 16419 | 63275322 |
Pulmonary fibrosis | 13.29 | 10.40 | 71 | 197210 | 39738 | 63252003 |
Drug-induced liver injury | 13.28 | 10.40 | 72 | 197209 | 40150 | 63251591 |
Atrioventricular block | 13.28 | 10.40 | 53 | 197228 | 7594 | 63284147 |
Metastases to liver | 13.27 | 10.40 | 34 | 197247 | 23605 | 63268136 |
Breast haemorrhage | 13.17 | 10.40 | 8 | 197273 | 189 | 63291552 |
Lupus endocarditis | 13.16 | 10.40 | 9 | 197272 | 262 | 63291479 |
Purpura | 13.15 | 10.40 | 70 | 197211 | 11315 | 63280426 |
Post procedural haematoma | 13.10 | 10.40 | 18 | 197263 | 1267 | 63290474 |
Lymphopenia | 13.10 | 10.40 | 23 | 197258 | 18304 | 63273437 |
Mental status changes | 13.09 | 10.40 | 184 | 197097 | 39415 | 63252326 |
Tricuspid valve incompetence | 13.06 | 10.40 | 84 | 197197 | 14537 | 63277204 |
Haematoma infection | 13.06 | 10.40 | 13 | 197268 | 647 | 63291094 |
Procedural haemorrhage | 13.03 | 10.40 | 27 | 197254 | 2661 | 63289080 |
Catheter site extravasation | 12.90 | 10.40 | 10 | 197271 | 355 | 63291386 |
Gastrointestinal toxicity | 12.88 | 10.40 | 4 | 197277 | 7737 | 63284004 |
Duodenal ulcer | 12.87 | 10.40 | 53 | 197228 | 7703 | 63284038 |
Coagulation time abnormal | 12.87 | 10.40 | 6 | 197275 | 81 | 63291660 |
Uveitis | 12.86 | 10.40 | 12 | 197269 | 12541 | 63279200 |
Influenza | 12.82 | 10.40 | 435 | 196846 | 108287 | 63183454 |
Hepatic infarction | 12.73 | 10.40 | 13 | 197268 | 667 | 63291074 |
Nephrogenic systemic fibrosis | 12.71 | 10.40 | 37 | 197244 | 4519 | 63287222 |
Steroid dependence | 12.69 | 10.40 | 21 | 197260 | 1743 | 63289998 |
Breast cancer | 12.68 | 10.40 | 93 | 197188 | 48290 | 63243451 |
Arteriovenous fistula site haemorrhage | 12.67 | 10.40 | 8 | 197273 | 203 | 63291538 |
Angioedema | 12.67 | 10.40 | 92 | 197189 | 47873 | 63243868 |
Pulmonary artery dilatation | 12.64 | 10.40 | 9 | 197272 | 280 | 63291461 |
Body temperature increased | 12.60 | 10.40 | 66 | 197215 | 37126 | 63254615 |
Demyelination | 12.60 | 10.40 | 3 | 197278 | 6917 | 63284824 |
Incarcerated umbilical hernia | 12.53 | 10.40 | 4 | 197277 | 17 | 63291724 |
Pancreatitis | 12.52 | 10.40 | 95 | 197186 | 48960 | 63242781 |
Localised oedema | 12.51 | 10.40 | 41 | 197240 | 5337 | 63286404 |
Drug withdrawal syndrome | 12.46 | 10.40 | 43 | 197238 | 27151 | 63264590 |
Venous haemorrhage | 12.42 | 10.40 | 9 | 197272 | 288 | 63291453 |
Pelvic haemorrhage | 12.39 | 10.40 | 7 | 197274 | 144 | 63291597 |
Poisoning deliberate | 12.37 | 10.40 | 10 | 197271 | 11208 | 63280533 |
Large intestinal haemorrhage | 12.37 | 10.40 | 18 | 197263 | 1336 | 63290405 |
Hyphaema | 12.37 | 10.40 | 9 | 197272 | 290 | 63291451 |
Blood blister | 12.36 | 10.40 | 22 | 197259 | 1936 | 63289805 |
Rehabilitation therapy | 12.35 | 10.40 | 20 | 197261 | 1630 | 63290111 |
Subcapsular renal haematoma | 12.29 | 10.40 | 9 | 197272 | 293 | 63291448 |
Aggression | 12.28 | 10.40 | 35 | 197246 | 23463 | 63268278 |
Infusion site induration | 12.28 | 10.40 | 17 | 197264 | 1205 | 63290536 |
Hepatic cytolysis | 12.27 | 10.40 | 18 | 197263 | 15389 | 63276352 |
Osteopenia | 12.26 | 10.40 | 27 | 197254 | 19758 | 63271983 |
Diet noncompliance | 12.25 | 10.40 | 10 | 197271 | 383 | 63291358 |
Weight increased | 12.23 | 10.40 | 674 | 196607 | 260118 | 63031623 |
Haemorrhage urinary tract | 12.18 | 10.40 | 14 | 197267 | 822 | 63290919 |
Renal stone removal | 12.18 | 10.40 | 7 | 197274 | 149 | 63291592 |
Acute generalised exanthematous pustulosis | 12.11 | 10.40 | 10 | 197271 | 11089 | 63280652 |
Pyelonephritis | 12.09 | 10.40 | 23 | 197258 | 17755 | 63273986 |
Creatinine renal clearance decreased | 12.08 | 10.40 | 20 | 197261 | 16288 | 63275453 |
Biopsy liver | 12.07 | 10.40 | 10 | 197271 | 391 | 63291350 |
Cardiac output decreased | 12.06 | 10.40 | 15 | 197266 | 957 | 63290784 |
Brachiocephalic vein thrombosis | 12.02 | 10.40 | 6 | 197275 | 95 | 63291646 |
Cardiac resynchronisation therapy | 12.00 | 10.40 | 4 | 197277 | 20 | 63291721 |
Infected skin ulcer | 11.99 | 10.40 | 24 | 197257 | 2308 | 63289433 |
Paraplegia | 11.98 | 10.40 | 26 | 197255 | 2646 | 63289095 |
Dermatomyositis | 11.97 | 10.40 | 27 | 197254 | 2821 | 63288920 |
Oxygen consumption | 11.91 | 10.40 | 6 | 197275 | 97 | 63291644 |
Bronchopulmonary aspergillosis | 11.85 | 10.40 | 6 | 197275 | 8629 | 63283112 |
Upper respiratory tract inflammation | 11.83 | 10.40 | 25 | 197256 | 2498 | 63289243 |
Arteriovenous fistula operation | 11.82 | 10.40 | 8 | 197273 | 229 | 63291512 |
Liver function test increased | 11.82 | 10.40 | 57 | 197224 | 32754 | 63258987 |
Skin discolouration | 11.80 | 10.40 | 174 | 197107 | 37654 | 63254087 |
Injection site pustule | 11.80 | 10.40 | 6 | 197275 | 99 | 63291642 |
Thyroiditis acute | 11.80 | 10.40 | 6 | 197275 | 99 | 63291642 |
Diverticulum intestinal haemorrhagic | 11.79 | 10.40 | 19 | 197262 | 1542 | 63290199 |
Aspiration pleural cavity | 11.77 | 10.40 | 14 | 197267 | 853 | 63290888 |
Ear infection | 11.76 | 10.40 | 70 | 197211 | 38143 | 63253598 |
Shock | 11.73 | 10.40 | 118 | 197163 | 23345 | 63268396 |
Low cardiac output syndrome | 11.65 | 10.40 | 10 | 197271 | 411 | 63291330 |
Myocarditis | 11.65 | 10.40 | 9 | 197272 | 10316 | 63281425 |
Premature labour | 11.62 | 10.40 | 13 | 197268 | 12491 | 63279250 |
Spinal cord haemorrhage | 11.61 | 10.40 | 8 | 197273 | 236 | 63291505 |
Nail disorder | 11.59 | 10.40 | 14 | 197267 | 13001 | 63278740 |
Transaminases increased | 11.58 | 10.40 | 54 | 197227 | 31313 | 63260428 |
Mitral valve incompetence | 11.52 | 10.40 | 102 | 197179 | 19492 | 63272249 |
Peripheral embolism | 11.52 | 10.40 | 17 | 197264 | 1278 | 63290463 |
Pulmonary arterial wedge pressure increased | 11.50 | 10.40 | 9 | 197272 | 324 | 63291417 |
Investigation | 11.40 | 10.40 | 19 | 197262 | 1586 | 63290155 |
Product administration error | 11.37 | 10.40 | 113 | 197168 | 22284 | 63269457 |
Heart transplant | 11.36 | 10.40 | 11 | 197270 | 529 | 63291212 |
Extremity necrosis | 11.33 | 10.40 | 19 | 197262 | 1594 | 63290147 |
Pharyngeal haematoma | 11.25 | 10.40 | 5 | 197276 | 60 | 63291681 |
Neuropathy peripheral | 11.24 | 10.40 | 268 | 197013 | 113399 | 63178342 |
Concomitant disease aggravated | 11.20 | 10.40 | 57 | 197224 | 9055 | 63282686 |
Catheter site hypersensitivity | 11.19 | 10.40 | 6 | 197275 | 111 | 63291630 |
Transaminases abnormal | 11.16 | 10.40 | 12 | 197269 | 654 | 63291087 |
Disease recurrence | 11.11 | 10.40 | 47 | 197234 | 27983 | 63263758 |
Hyponatraemic syndrome | 11.11 | 10.40 | 11 | 197270 | 544 | 63291197 |
Heart valve incompetence | 11.08 | 10.40 | 26 | 197255 | 2788 | 63288953 |
Iliac artery embolism | 11.05 | 10.40 | 3 | 197278 | 6 | 63291735 |
Craniectomy | 11.05 | 10.40 | 3 | 197278 | 6 | 63291735 |
Finger amputation | 11.04 | 10.40 | 11 | 197270 | 548 | 63291193 |
Hypomania | 11.03 | 10.40 | 3 | 197278 | 6327 | 63285414 |
Pulmonary resection | 11.00 | 10.40 | 4 | 197277 | 27 | 63291714 |
Aortic surgery | 11.00 | 10.40 | 4 | 197277 | 27 | 63291714 |
Right atrial dilatation | 11.00 | 10.40 | 12 | 197269 | 665 | 63291076 |
Status epilepticus | 10.99 | 10.40 | 19 | 197262 | 15214 | 63276527 |
Poor peripheral circulation | 10.99 | 10.40 | 31 | 197250 | 3718 | 63288023 |
Inadequate diet | 10.97 | 10.40 | 7 | 197274 | 181 | 63291560 |
Migraine | 10.97 | 10.40 | 241 | 197040 | 103105 | 63188636 |
Somnolence | 10.97 | 10.40 | 669 | 196612 | 178016 | 63113725 |
Hernia obstructive | 10.95 | 10.40 | 6 | 197275 | 116 | 63291625 |
Gravitational oedema | 10.89 | 10.40 | 16 | 197265 | 1198 | 63290543 |
Pathological fracture | 10.89 | 10.40 | 7 | 197274 | 8827 | 63282914 |
Heart rate abnormal | 10.87 | 10.40 | 37 | 197244 | 4910 | 63286831 |
Maternal exposure before pregnancy | 10.86 | 10.40 | 5 | 197276 | 7598 | 63284143 |
Dermatitis allergic | 10.84 | 10.40 | 19 | 197262 | 15129 | 63276612 |
N-terminal prohormone brain natriuretic peptide increased | 10.82 | 10.40 | 22 | 197259 | 2139 | 63289602 |
Renal haemorrhage | 10.82 | 10.40 | 14 | 197267 | 930 | 63290811 |
Mallory-Weiss syndrome | 10.80 | 10.40 | 18 | 197263 | 1503 | 63290238 |
Chronic obstructive pulmonary disease | 10.76 | 10.40 | 263 | 197018 | 62423 | 63229318 |
Metastases to central nervous system | 10.74 | 10.40 | 15 | 197266 | 13090 | 63278651 |
Encephalopathy | 10.72 | 10.40 | 73 | 197208 | 38547 | 63253194 |
Polyneuropathy | 10.71 | 10.40 | 18 | 197263 | 14571 | 63277170 |
Hepatic haematoma | 10.65 | 10.40 | 10 | 197271 | 463 | 63291278 |
Cardiac function disturbance postoperative | 10.64 | 10.40 | 4 | 197277 | 30 | 63291711 |
Blood pressure systolic increased | 10.63 | 10.40 | 95 | 197186 | 47302 | 63244439 |
Colon operation | 10.63 | 10.40 | 9 | 197272 | 363 | 63291378 |
Incision site haemorrhage | 10.62 | 10.40 | 11 | 197270 | 574 | 63291167 |
Vessel puncture site haemorrhage | 10.59 | 10.40 | 6 | 197275 | 124 | 63291617 |
Subchorionic haematoma | 10.55 | 10.40 | 6 | 197275 | 125 | 63291616 |
Suture insertion | 10.54 | 10.40 | 8 | 197273 | 275 | 63291466 |
Device malfunction | 10.52 | 10.40 | 93 | 197188 | 17764 | 63273977 |
Paracentesis | 10.52 | 10.40 | 14 | 197267 | 956 | 63290785 |
Unintentional medical device removal | 10.46 | 10.40 | 3 | 197278 | 6112 | 63285629 |
Cerebral artery thrombosis | 10.46 | 10.40 | 9 | 197272 | 371 | 63291370 |
Maxillonasal dysplasia | 10.46 | 10.40 | 3 | 197278 | 8 | 63291733 |
Skin fissures | 10.41 | 10.40 | 12 | 197269 | 11376 | 63280365 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
International normalised ratio increased | 11187.21 | 10.73 | 5190 | 168106 | 42137 | 34741498 |
Gastric haemorrhage | 2029.01 | 10.73 | 999 | 172297 | 9262 | 34774373 |
Haemorrhage | 1965.97 | 10.73 | 1792 | 171504 | 49578 | 34734057 |
International normalised ratio abnormal | 1809.54 | 10.73 | 665 | 172631 | 2670 | 34780965 |
International normalised ratio decreased | 1205.73 | 10.73 | 543 | 172753 | 4024 | 34779611 |
Gastrointestinal haemorrhage | 1070.93 | 10.73 | 1718 | 171578 | 86759 | 34696876 |
Anticoagulation drug level above therapeutic | 1027.43 | 10.73 | 389 | 172907 | 1727 | 34781908 |
Drug interaction | 849.65 | 10.73 | 2752 | 170544 | 223194 | 34560441 |
Haematuria | 736.31 | 10.73 | 1065 | 172231 | 49001 | 34734634 |
Subdural haematoma | 734.59 | 10.73 | 689 | 172607 | 19732 | 34763903 |
Haematoma | 715.70 | 10.73 | 753 | 172543 | 24852 | 34758783 |
Melaena | 619.71 | 10.73 | 819 | 172477 | 34561 | 34749074 |
Haemorrhage intracranial | 606.33 | 10.73 | 555 | 172741 | 15391 | 34768244 |
Epistaxis | 528.61 | 10.73 | 997 | 172299 | 57254 | 34726381 |
Anticoagulation drug level below therapeutic | 507.68 | 10.73 | 183 | 173113 | 685 | 34782950 |
International normalised ratio fluctuation | 459.77 | 10.73 | 189 | 173107 | 1085 | 34782550 |
Calciphylaxis | 424.92 | 10.73 | 171 | 173125 | 921 | 34782714 |
Haemoglobin decreased | 353.74 | 10.73 | 1357 | 171939 | 119415 | 34664220 |
Febrile neutropenia | 353.19 | 10.73 | 119 | 173177 | 136730 | 34646905 |
Rectal haemorrhage | 349.06 | 10.73 | 676 | 172620 | 39573 | 34744062 |
Labelled drug-drug interaction medication error | 345.64 | 10.73 | 398 | 172898 | 14541 | 34769094 |
Cerebral haemorrhage | 336.82 | 10.73 | 614 | 172682 | 34323 | 34749312 |
Prothrombin time prolonged | 324.08 | 10.73 | 310 | 172986 | 9096 | 34774539 |
Anaemia | 323.76 | 10.73 | 2120 | 171176 | 231215 | 34552420 |
Off label use | 322.85 | 10.73 | 1039 | 172257 | 418485 | 34365150 |
Drug ineffective | 280.69 | 10.73 | 1240 | 172056 | 455511 | 34328124 |
Haemoptysis | 258.38 | 10.73 | 550 | 172746 | 34456 | 34749179 |
Cardiac failure congestive | 256.29 | 10.73 | 951 | 172345 | 82319 | 34701316 |
Coagulopathy | 247.99 | 10.73 | 391 | 172905 | 19398 | 34764237 |
Drug abuse | 247.29 | 10.73 | 91 | 173205 | 99005 | 34684630 |
Fall | 242.48 | 10.73 | 1778 | 171518 | 201107 | 34582528 |
Muscle haemorrhage | 241.89 | 10.73 | 177 | 173119 | 3541 | 34780094 |
Pyrexia | 239.16 | 10.73 | 849 | 172447 | 332164 | 34451471 |
Cardiac failure | 208.71 | 10.73 | 951 | 172345 | 90297 | 34693338 |
Upper gastrointestinal haemorrhage | 204.77 | 10.73 | 415 | 172881 | 25103 | 34758532 |
Faeces discoloured | 203.29 | 10.73 | 306 | 172990 | 14572 | 34769063 |
Abdominal wall haematoma | 193.42 | 10.73 | 118 | 173178 | 1719 | 34781916 |
Subarachnoid haemorrhage | 185.79 | 10.73 | 269 | 173027 | 12366 | 34771269 |
Neutropenia | 184.76 | 10.73 | 308 | 172988 | 156470 | 34627165 |
Retroperitoneal haematoma | 184.50 | 10.73 | 132 | 173164 | 2546 | 34781089 |
Pulmonary arterial hypertension | 164.87 | 10.73 | 210 | 173086 | 8529 | 34775106 |
Haematocrit decreased | 164.83 | 10.73 | 439 | 172857 | 31777 | 34751858 |
Contusion | 163.79 | 10.73 | 473 | 172823 | 35891 | 34747744 |
Ecchymosis | 160.29 | 10.73 | 183 | 173113 | 6620 | 34777015 |
Subdural haemorrhage | 157.58 | 10.73 | 129 | 173167 | 3062 | 34780573 |
Retroperitoneal haemorrhage | 149.47 | 10.73 | 120 | 173176 | 2768 | 34780867 |
Fluid retention | 139.17 | 10.73 | 368 | 172928 | 26519 | 34757116 |
Haematemesis | 137.11 | 10.73 | 373 | 172923 | 27338 | 34756297 |
Coagulation time prolonged | 135.46 | 10.73 | 83 | 173213 | 1219 | 34782416 |
Foetal warfarin syndrome | 133.67 | 10.73 | 31 | 173265 | 0 | 34783635 |
Product use in unapproved indication | 131.81 | 10.73 | 238 | 173058 | 117261 | 34666374 |
Atrial fibrillation | 126.09 | 10.73 | 1037 | 172259 | 121356 | 34662279 |
COVID-19 | 118.08 | 10.73 | 126 | 173170 | 77424 | 34706211 |
Intra-abdominal haematoma | 111.94 | 10.73 | 75 | 173221 | 1295 | 34782340 |
Haemarthrosis | 111.47 | 10.73 | 107 | 173189 | 3152 | 34780483 |
Right ventricular failure | 109.24 | 10.73 | 173 | 173123 | 8611 | 34775024 |
Depression | 108.59 | 10.73 | 197 | 173099 | 96901 | 34686734 |
Intraventricular haemorrhage | 102.43 | 10.73 | 106 | 173190 | 3425 | 34780210 |
Thrombosis | 102.23 | 10.73 | 508 | 172788 | 49950 | 34733685 |
Pulmonary hypertension | 101.86 | 10.73 | 280 | 173016 | 20644 | 34762991 |
Lower gastrointestinal haemorrhage | 99.87 | 10.73 | 173 | 173123 | 9279 | 34774356 |
Mucosal inflammation | 98.77 | 10.73 | 34 | 173262 | 38588 | 34745047 |
Haematoma muscle | 97.86 | 10.73 | 69 | 173227 | 1299 | 34782336 |
Head injury | 95.44 | 10.73 | 250 | 173046 | 17910 | 34765725 |
Dyspnoea | 93.97 | 10.73 | 2487 | 170809 | 374295 | 34409340 |
Occult blood positive | 93.86 | 10.73 | 108 | 173188 | 3940 | 34779695 |
Transfusion | 93.16 | 10.73 | 159 | 173137 | 8426 | 34775209 |
Cytokine release syndrome | 92.84 | 10.73 | 5 | 173291 | 22872 | 34760763 |
Malignant neoplasm progression | 89.47 | 10.73 | 189 | 173107 | 87857 | 34695778 |
Intentional overdose | 87.60 | 10.73 | 54 | 173242 | 43620 | 34740015 |
Shock haemorrhagic | 85.58 | 10.73 | 180 | 173116 | 11174 | 34772461 |
Infusion related reaction | 85.55 | 10.73 | 82 | 173214 | 52975 | 34730660 |
Anticoagulant-related nephropathy | 85.07 | 10.73 | 24 | 173272 | 28 | 34783607 |
Blood loss anaemia | 84.01 | 10.73 | 148 | 173148 | 8046 | 34775589 |
Ear haemorrhage | 83.43 | 10.73 | 55 | 173241 | 923 | 34782712 |
Deep vein thrombosis | 82.34 | 10.73 | 580 | 172716 | 64668 | 34718967 |
Cerebral mass effect | 80.76 | 10.73 | 54 | 173242 | 929 | 34782706 |
Appendicolith | 80.10 | 10.73 | 149 | 173147 | 8452 | 34775183 |
Suicide attempt | 78.96 | 10.73 | 48 | 173248 | 39068 | 34744567 |
Activated partial thromboplastin time prolonged | 78.94 | 10.73 | 149 | 173147 | 8546 | 34775089 |
Spinal epidural haematoma | 78.09 | 10.73 | 36 | 173260 | 283 | 34783352 |
Gingival bleeding | 77.75 | 10.73 | 131 | 173165 | 6869 | 34776766 |
Leukopenia | 77.20 | 10.73 | 120 | 173176 | 62736 | 34720899 |
Intestinal haematoma | 75.73 | 10.73 | 26 | 173270 | 81 | 34783554 |
Therapeutic product effect incomplete | 74.83 | 10.73 | 84 | 173212 | 50457 | 34733178 |
Completed suicide | 74.37 | 10.73 | 244 | 173052 | 97924 | 34685711 |
Anaphylactic reaction | 71.95 | 10.73 | 35 | 173261 | 32266 | 34751369 |
Cerebrovascular accident | 71.48 | 10.73 | 688 | 172608 | 84123 | 34699512 |
Agitation | 71.05 | 10.73 | 109 | 173187 | 57290 | 34726345 |
Pain in jaw | 70.04 | 10.73 | 181 | 173115 | 12859 | 34770776 |
Pulmonary alveolar haemorrhage | 69.78 | 10.73 | 130 | 173166 | 7382 | 34776253 |
Drug dependence | 67.93 | 10.73 | 18 | 173278 | 24199 | 34759436 |
Prothrombin time ratio increased | 67.45 | 10.73 | 27 | 173269 | 143 | 34783492 |
Foetal exposure during pregnancy | 67.32 | 10.73 | 54 | 173242 | 38047 | 34745588 |
Cardiac tamponade | 67.26 | 10.73 | 105 | 173191 | 5161 | 34778474 |
Pancytopenia | 67.03 | 10.73 | 244 | 173052 | 94913 | 34688722 |
Product use issue | 66.49 | 10.73 | 133 | 173163 | 63083 | 34720552 |
Oedema peripheral | 64.95 | 10.73 | 892 | 172404 | 118920 | 34664715 |
Extradural haematoma | 64.95 | 10.73 | 51 | 173245 | 1138 | 34782497 |
Ventricular tachycardia | 64.40 | 10.73 | 282 | 173014 | 26297 | 34757338 |
Dizziness | 64.31 | 10.73 | 1476 | 171820 | 217045 | 34566590 |
Arthralgia | 63.64 | 10.73 | 538 | 172758 | 169503 | 34614132 |
Oedema | 63.29 | 10.73 | 416 | 172880 | 45325 | 34738310 |
Haemorrhage subcutaneous | 62.49 | 10.73 | 67 | 173229 | 2257 | 34781378 |
Intentional product use issue | 61.08 | 10.73 | 128 | 173168 | 59688 | 34723947 |
Thrombocytopenia | 60.44 | 10.73 | 490 | 172806 | 155757 | 34627878 |
Skin necrosis | 60.37 | 10.73 | 106 | 173190 | 5747 | 34777888 |
Heparin-induced thrombocytopenia | 59.89 | 10.73 | 103 | 173193 | 5492 | 34778143 |
Cardiogenic shock | 59.69 | 10.73 | 276 | 173020 | 26342 | 34757293 |
Neutrophil count decreased | 59.53 | 10.73 | 101 | 173195 | 51003 | 34732632 |
Disease progression | 57.97 | 10.73 | 307 | 172989 | 107770 | 34675865 |
Post procedural haemorrhage | 57.42 | 10.73 | 127 | 173169 | 8162 | 34775473 |
Stomatitis | 57.29 | 10.73 | 76 | 173220 | 42438 | 34741197 |
Conjunctival haemorrhage | 56.97 | 10.73 | 73 | 173223 | 2982 | 34780653 |
Haemorrhagic stroke | 56.83 | 10.73 | 110 | 173186 | 6429 | 34777206 |
Toxicity to various agents | 55.90 | 10.73 | 680 | 172616 | 199682 | 34583953 |
Asthma | 55.72 | 10.73 | 78 | 173218 | 42578 | 34741057 |
Seizure | 55.60 | 10.73 | 299 | 172997 | 104558 | 34679077 |
Compartment syndrome | 54.53 | 10.73 | 71 | 173225 | 2947 | 34780688 |
Synovitis | 54.31 | 10.73 | 4 | 173292 | 14062 | 34769573 |
Rheumatoid arthritis | 53.97 | 10.73 | 66 | 173230 | 38172 | 34745463 |
Hepatic cytolysis | 53.55 | 10.73 | 5 | 173291 | 14491 | 34769144 |
Hypervolaemia | 53.10 | 10.73 | 216 | 173080 | 19493 | 34764142 |
Traumatic haematoma | 52.91 | 10.73 | 37 | 173259 | 687 | 34782948 |
Cytomegalovirus infection | 52.84 | 10.73 | 32 | 173264 | 26103 | 34757532 |
Myelosuppression | 52.76 | 10.73 | 15 | 173281 | 19250 | 34764385 |
Acute myeloid leukaemia | 52.35 | 10.73 | 13 | 173283 | 18257 | 34765378 |
Pain | 52.15 | 10.73 | 708 | 172588 | 203967 | 34579668 |
Drug hypersensitivity | 51.88 | 10.73 | 214 | 173082 | 80315 | 34703320 |
Atrial flutter | 51.31 | 10.73 | 182 | 173114 | 15392 | 34768243 |
Gastritis erosive | 50.60 | 10.73 | 99 | 173197 | 5833 | 34777802 |
Transient ischaemic attack | 49.66 | 10.73 | 269 | 173027 | 27344 | 34756291 |
Rash | 49.65 | 10.73 | 791 | 172505 | 221961 | 34561674 |
Device alarm issue | 49.62 | 10.73 | 34 | 173262 | 610 | 34783025 |
Aggression | 49.17 | 10.73 | 73 | 173223 | 38891 | 34744744 |
Suicidal ideation | 48.73 | 10.73 | 78 | 173218 | 40310 | 34743325 |
Haemoperitoneum | 48.30 | 10.73 | 52 | 173244 | 1760 | 34781875 |
Scrotal haematoma | 48.24 | 10.73 | 18 | 173278 | 76 | 34783559 |
Colitis | 47.37 | 10.73 | 71 | 173225 | 37679 | 34745956 |
Cardiac failure chronic | 47.18 | 10.73 | 114 | 173182 | 7765 | 34775870 |
Ventricular fibrillation | 47.10 | 10.73 | 232 | 173064 | 22722 | 34760913 |
Cerebellar haemorrhage | 47.09 | 10.73 | 48 | 173248 | 1523 | 34782112 |
Rash maculo-papular | 46.99 | 10.73 | 43 | 173253 | 28408 | 34755227 |
Cholestasis | 46.60 | 10.73 | 39 | 173257 | 26909 | 34756726 |
Chills | 46.41 | 10.73 | 225 | 173071 | 80818 | 34702817 |
Dyspnoea exertional | 46.25 | 10.73 | 370 | 172926 | 42909 | 34740726 |
Catheter site erythema | 45.98 | 10.73 | 45 | 173251 | 1358 | 34782277 |
White blood cell count decreased | 45.84 | 10.73 | 281 | 173015 | 95164 | 34688471 |
Gastric ulcer | 45.78 | 10.73 | 176 | 173120 | 15474 | 34768161 |
Prostate cancer | 45.59 | 10.73 | 79 | 173217 | 39570 | 34744065 |
Spontaneous haematoma | 45.58 | 10.73 | 30 | 173266 | 502 | 34783133 |
Device interaction | 45.49 | 10.73 | 31 | 173265 | 551 | 34783084 |
Angioedema | 45.26 | 10.73 | 72 | 173224 | 37302 | 34746333 |
Gastrointestinal arteriovenous malformation | 45.04 | 10.73 | 26 | 173270 | 340 | 34783295 |
Mesenteric haematoma | 44.85 | 10.73 | 13 | 173283 | 18 | 34783617 |
Lymphopenia | 44.21 | 10.73 | 13 | 173283 | 16322 | 34767313 |
Haematochezia | 43.98 | 10.73 | 387 | 172909 | 46147 | 34737488 |
Gastric ulcer haemorrhage | 43.95 | 10.73 | 89 | 173207 | 5377 | 34778258 |
Appendicitis | 43.71 | 10.73 | 167 | 173129 | 14640 | 34768995 |
Catheter management | 43.48 | 10.73 | 37 | 173259 | 928 | 34782707 |
Subcutaneous haematoma | 42.36 | 10.73 | 37 | 173259 | 962 | 34782673 |
Intentional product misuse | 42.17 | 10.73 | 103 | 173193 | 45508 | 34738127 |
Urticaria | 41.92 | 10.73 | 163 | 173133 | 62214 | 34721421 |
Anxiety | 41.61 | 10.73 | 305 | 172991 | 99123 | 34684512 |
Mallory-Weiss syndrome | 40.96 | 10.73 | 42 | 173254 | 1342 | 34782293 |
Hyphaema | 40.59 | 10.73 | 29 | 173267 | 558 | 34783077 |
Cardiac failure acute | 40.54 | 10.73 | 130 | 173166 | 10440 | 34773195 |
Hypotension | 40.44 | 10.73 | 1409 | 171887 | 220240 | 34563395 |
Chest wall haematoma | 40.33 | 10.73 | 20 | 173276 | 188 | 34783447 |
Neoplasm progression | 39.95 | 10.73 | 34 | 173262 | 23266 | 34760369 |
Psoriasis | 39.66 | 10.73 | 83 | 173213 | 38729 | 34744906 |
General physical health deterioration | 39.37 | 10.73 | 426 | 172870 | 127843 | 34655792 |
Thrombosis in device | 39.31 | 10.73 | 64 | 173232 | 3261 | 34780374 |
Hyperhidrosis | 38.92 | 10.73 | 218 | 173078 | 75474 | 34708161 |
Pruritus | 38.74 | 10.73 | 484 | 172812 | 141497 | 34642138 |
Generalised tonic-clonic seizure | 38.68 | 10.73 | 29 | 173267 | 21145 | 34762490 |
Injection site pain | 38.53 | 10.73 | 85 | 173211 | 38920 | 34744715 |
International normalised ratio | 37.98 | 10.73 | 13 | 173283 | 40 | 34783595 |
Renal haemorrhage | 37.42 | 10.73 | 41 | 173255 | 1416 | 34782219 |
Mouth haemorrhage | 37.41 | 10.73 | 82 | 173214 | 5237 | 34778398 |
Hepatocellular injury | 37.36 | 10.73 | 33 | 173263 | 22178 | 34761457 |
Psychotic disorder | 36.89 | 10.73 | 40 | 173256 | 24412 | 34759223 |
Penile necrosis | 36.62 | 10.73 | 13 | 173283 | 46 | 34783589 |
Prothrombin time abnormal | 36.43 | 10.73 | 30 | 173266 | 718 | 34782917 |
Disturbance in attention | 36.38 | 10.73 | 45 | 173251 | 25900 | 34757735 |
Alanine aminotransferase increased | 36.21 | 10.73 | 243 | 173053 | 80572 | 34703063 |
Hypertension | 36.16 | 10.73 | 468 | 172828 | 135975 | 34647660 |
Haematoma evacuation | 36.14 | 10.73 | 18 | 173278 | 171 | 34783464 |
Hypercoagulation | 35.68 | 10.73 | 38 | 173258 | 1270 | 34782365 |
Bronchopulmonary aspergillosis | 35.62 | 10.73 | 14 | 173282 | 14645 | 34768990 |
Pancreatitis acute | 35.23 | 10.73 | 53 | 173243 | 28088 | 34755547 |
Diabetic ketoacidosis | 35.18 | 10.73 | 23 | 173273 | 18009 | 34765626 |
Catheter site haemorrhage | 35.12 | 10.73 | 49 | 173247 | 2175 | 34781460 |
Pancreatitis | 35.03 | 10.73 | 89 | 173207 | 38802 | 34744833 |
Syncope | 34.82 | 10.73 | 642 | 172654 | 90809 | 34692826 |
Musculoskeletal stiffness | 34.65 | 10.73 | 117 | 173179 | 46563 | 34737072 |
Venous pressure jugular increased | 34.64 | 10.73 | 30 | 173266 | 771 | 34782864 |
Thalamus haemorrhage | 34.38 | 10.73 | 33 | 173263 | 972 | 34782663 |
Diverticulum intestinal haemorrhagic | 34.31 | 10.73 | 52 | 173244 | 2490 | 34781145 |
Lymphadenopathy | 34.31 | 10.73 | 55 | 173241 | 28408 | 34755227 |
Serotonin syndrome | 34.28 | 10.73 | 29 | 173267 | 19904 | 34763731 |
Therapeutic product effect decreased | 34.08 | 10.73 | 76 | 173220 | 34667 | 34748968 |
Infection | 33.80 | 10.73 | 288 | 173008 | 90627 | 34693008 |
Blood phosphorus increased | 33.37 | 10.73 | 99 | 173197 | 7622 | 34776013 |
Exposure during pregnancy | 33.22 | 10.73 | 3 | 173293 | 8931 | 34774704 |
Accidental exposure to product | 33.19 | 10.73 | 11 | 173285 | 12791 | 34770844 |
Blood pressure fluctuation | 33.14 | 10.73 | 46 | 173250 | 25203 | 34758432 |
Product dose omission issue | 33.06 | 10.73 | 407 | 172889 | 119304 | 34664331 |
Implant site haematoma | 32.61 | 10.73 | 13 | 173283 | 68 | 34783567 |
Psoriatic arthropathy | 32.60 | 10.73 | 30 | 173266 | 19768 | 34763867 |
Drug intolerance | 32.60 | 10.73 | 168 | 173128 | 59402 | 34724233 |
Insomnia | 32.31 | 10.73 | 344 | 172952 | 103563 | 34680072 |
Sinusitis | 31.96 | 10.73 | 102 | 173194 | 41300 | 34742335 |
Extrapyramidal disorder | 31.80 | 10.73 | 12 | 173284 | 12868 | 34770767 |
Catheter site discharge | 31.76 | 10.73 | 26 | 173270 | 617 | 34783018 |
Tumour lysis syndrome | 31.63 | 10.73 | 23 | 173273 | 17036 | 34766599 |
Therapy partial responder | 31.40 | 10.73 | 5 | 173291 | 9611 | 34774024 |
Drug ineffective for unapproved indication | 31.33 | 10.73 | 43 | 173253 | 23672 | 34759963 |
Pericardial haemorrhage | 31.03 | 10.73 | 56 | 173240 | 3102 | 34780533 |
Restlessness | 30.94 | 10.73 | 49 | 173247 | 25433 | 34758202 |
Oxygen consumption increased | 30.92 | 10.73 | 36 | 173260 | 1330 | 34782305 |
Intracardiac thrombus | 30.81 | 10.73 | 49 | 173247 | 2447 | 34781188 |
Treatment failure | 30.75 | 10.73 | 123 | 173173 | 46574 | 34737061 |
Haemorrhagic diathesis | 30.35 | 10.73 | 52 | 173244 | 2764 | 34780871 |
Internal haemorrhage | 30.25 | 10.73 | 73 | 173223 | 4968 | 34778667 |
Blood urine present | 30.19 | 10.73 | 120 | 173176 | 10714 | 34772921 |
Food interaction | 30.18 | 10.73 | 30 | 173266 | 923 | 34782712 |
Small intestinal haemorrhage | 29.74 | 10.73 | 44 | 173252 | 2062 | 34781573 |
Pelvic haematoma | 29.49 | 10.73 | 16 | 173280 | 184 | 34783451 |
Atrial thrombosis | 29.47 | 10.73 | 45 | 173251 | 2169 | 34781466 |
Abnormal behaviour | 29.39 | 10.73 | 49 | 173247 | 24920 | 34758715 |
Aspergillus infection | 29.29 | 10.73 | 12 | 173284 | 12242 | 34771393 |
Traumatic intracranial haemorrhage | 29.26 | 10.73 | 26 | 173270 | 692 | 34782943 |
Cardiac pacemaker insertion | 29.26 | 10.73 | 52 | 173244 | 2846 | 34780789 |
Duodenal ulcer | 29.24 | 10.73 | 115 | 173181 | 10217 | 34773418 |
Lymphocyte count decreased | 28.91 | 10.73 | 42 | 173254 | 22580 | 34761055 |
COVID-19 pneumonia | 28.79 | 10.73 | 25 | 173271 | 16942 | 34766693 |
Bone marrow failure | 28.69 | 10.73 | 64 | 173232 | 29189 | 34754446 |
Posterior reversible encephalopathy syndrome | 28.68 | 10.73 | 7 | 173289 | 9947 | 34773688 |
Mediastinal haematoma | 28.55 | 10.73 | 13 | 173283 | 99 | 34783536 |
Choroidal haemorrhage | 28.48 | 10.73 | 12 | 173284 | 74 | 34783561 |
Abdominal distension | 28.28 | 10.73 | 427 | 172869 | 58065 | 34725570 |
Hypokalaemia | 28.14 | 10.73 | 171 | 173125 | 58043 | 34725592 |
Multiple sclerosis relapse | 28.09 | 10.73 | 15 | 173281 | 13118 | 34770517 |
Adrenal haemorrhage | 27.73 | 10.73 | 16 | 173280 | 209 | 34783426 |
Aplastic anaemia | 27.67 | 10.73 | 7 | 173289 | 9709 | 34773926 |
Premature baby | 27.58 | 10.73 | 34 | 173262 | 19599 | 34764036 |
Blue toe syndrome | 27.49 | 10.73 | 14 | 173282 | 140 | 34783495 |
Gamma-glutamyltransferase increased | 27.02 | 10.73 | 66 | 173230 | 29165 | 34754470 |
Cardioversion | 27.00 | 10.73 | 28 | 173268 | 907 | 34782728 |
Cerebral haematoma | 26.81 | 10.73 | 66 | 173230 | 4549 | 34779086 |
Irritability | 26.77 | 10.73 | 51 | 173245 | 24639 | 34758996 |
Arteriovenous malformation | 26.69 | 10.73 | 26 | 173270 | 780 | 34782855 |
Haemothorax | 26.66 | 10.73 | 59 | 173237 | 3793 | 34779842 |
Pneumonitis | 26.47 | 10.73 | 83 | 173213 | 33795 | 34749840 |
Asthenia | 26.44 | 10.73 | 1477 | 171819 | 243774 | 34539861 |
Hepatotoxicity | 26.38 | 10.73 | 41 | 173255 | 21444 | 34762191 |
Neuroleptic malignant syndrome | 26.33 | 10.73 | 30 | 173266 | 17904 | 34765731 |
Hypertriglyceridaemia | 26.26 | 10.73 | 5 | 173291 | 8443 | 34775192 |
Hyperbilirubinaemia | 26.02 | 10.73 | 27 | 173269 | 16816 | 34766819 |
Neutrophil count increased | 25.92 | 10.73 | 28 | 173268 | 17118 | 34766517 |
Pneumocystis jirovecii pneumonia | 25.78 | 10.73 | 36 | 173260 | 19674 | 34763961 |
Pulmonary embolism | 25.63 | 10.73 | 604 | 172692 | 89142 | 34694493 |
Epilepsy | 25.47 | 10.73 | 42 | 173254 | 21453 | 34762182 |
Coma | 25.45 | 10.73 | 128 | 173168 | 45550 | 34738085 |
Duodenal ulcer haemorrhage | 25.31 | 10.73 | 68 | 173228 | 4945 | 34778690 |
Drug resistance | 25.20 | 10.73 | 57 | 173239 | 25870 | 34757765 |
C-reactive protein increased | 25.07 | 10.73 | 161 | 173135 | 53937 | 34729698 |
Sedation | 24.93 | 10.73 | 41 | 173255 | 20965 | 34762670 |
Colonic haematoma | 24.90 | 10.73 | 9 | 173287 | 34 | 34783601 |
Substance abuse | 24.89 | 10.73 | 4 | 173292 | 7637 | 34775998 |
Hypochromasia | 24.86 | 10.73 | 17 | 173279 | 304 | 34783331 |
Coagulation time shortened | 24.85 | 10.73 | 15 | 173281 | 214 | 34783421 |
Steroid dependence | 24.82 | 10.73 | 34 | 173262 | 1483 | 34782152 |
Product administration error | 24.67 | 10.73 | 152 | 173144 | 16192 | 34767443 |
Cerebral artery embolism | 24.58 | 10.73 | 26 | 173270 | 862 | 34782773 |
Hepatic steatosis | 24.55 | 10.73 | 33 | 173263 | 18329 | 34765306 |
Anticoagulation drug level decreased | 24.55 | 10.73 | 12 | 173284 | 109 | 34783526 |
Blood pressure increased | 24.51 | 10.73 | 299 | 172997 | 87803 | 34695832 |
Sleep disorder | 24.50 | 10.73 | 78 | 173218 | 31610 | 34752025 |
Sopor | 24.42 | 10.73 | 122 | 173174 | 12014 | 34771621 |
Oesophageal carcinoma | 24.11 | 10.73 | 8 | 173288 | 9296 | 34774339 |
Catheter site pruritus | 24.07 | 10.73 | 17 | 173279 | 321 | 34783314 |
Joint swelling | 23.95 | 10.73 | 186 | 173110 | 59704 | 34723931 |
Septic shock | 23.89 | 10.73 | 234 | 173062 | 71600 | 34712035 |
Diverticulum | 23.87 | 10.73 | 84 | 173212 | 7075 | 34776560 |
Tremor | 23.85 | 10.73 | 278 | 173018 | 82309 | 34701326 |
Medical device site thrombosis | 23.77 | 10.73 | 8 | 173288 | 23 | 34783612 |
Dyskinesia | 23.69 | 10.73 | 47 | 173249 | 22366 | 34761269 |
Immune reconstitution inflammatory syndrome | 23.65 | 10.73 | 7 | 173289 | 8752 | 34774883 |
Therapeutic product effect increased | 23.61 | 10.73 | 23 | 173273 | 690 | 34782945 |
Spinal subdural haematoma | 23.55 | 10.73 | 10 | 173286 | 63 | 34783572 |
Hallucination, auditory | 23.52 | 10.73 | 15 | 173281 | 11902 | 34771733 |
Sinus tachycardia | 23.42 | 10.73 | 31 | 173265 | 17329 | 34766306 |
Haemophagocytic lymphohistiocytosis | 23.40 | 10.73 | 18 | 173278 | 12955 | 34770680 |
Hepatic enzyme increased | 23.24 | 10.73 | 107 | 173189 | 38973 | 34744662 |
Hypocoagulable state | 23.22 | 10.73 | 26 | 173270 | 920 | 34782715 |
Complication associated with device | 23.15 | 10.73 | 74 | 173222 | 5932 | 34777703 |
Cardiac operation | 23.11 | 10.73 | 49 | 173247 | 3058 | 34780577 |
Death | 23.05 | 10.73 | 1681 | 171615 | 396368 | 34387267 |
Neuropathy peripheral | 23.00 | 10.73 | 283 | 173013 | 82980 | 34700655 |
Laryngeal haematoma | 22.92 | 10.73 | 13 | 173283 | 164 | 34783471 |
Hypersensitivity | 22.83 | 10.73 | 193 | 173103 | 60842 | 34722793 |
Subarachnoid haematoma | 22.74 | 10.73 | 15 | 173281 | 252 | 34783383 |
Depressed mood | 22.65 | 10.73 | 38 | 173258 | 19279 | 34764356 |
Potentiating drug interaction | 22.64 | 10.73 | 65 | 173231 | 4912 | 34778723 |
Lung transplant | 22.64 | 10.73 | 38 | 173258 | 1986 | 34781649 |
Medical device change | 22.58 | 10.73 | 12 | 173284 | 132 | 34783503 |
Intraocular haematoma | 22.56 | 10.73 | 7 | 173289 | 14 | 34783621 |
Haemorrhoidal haemorrhage | 22.55 | 10.73 | 54 | 173242 | 3657 | 34779978 |
Intentional self-injury | 22.52 | 10.73 | 21 | 173275 | 13750 | 34769885 |
Alopecia | 22.50 | 10.73 | 55 | 173241 | 24300 | 34759335 |
Inflammation | 22.33 | 10.73 | 69 | 173227 | 28226 | 34755409 |
Dystonia | 22.31 | 10.73 | 13 | 173283 | 10832 | 34772803 |
Product complaint | 22.19 | 10.73 | 72 | 173224 | 5818 | 34777817 |
Antiphospholipid syndrome | 22.14 | 10.73 | 19 | 173277 | 482 | 34783153 |
Atheroembolism | 22.12 | 10.73 | 16 | 173280 | 314 | 34783321 |
Embolic stroke | 22.06 | 10.73 | 60 | 173236 | 4394 | 34779241 |
Anger | 22.06 | 10.73 | 16 | 173280 | 11868 | 34771767 |
Nephropathy | 21.99 | 10.73 | 72 | 173224 | 5845 | 34777790 |
Haemorrhagic arteriovenous malformation | 21.89 | 10.73 | 17 | 173279 | 373 | 34783262 |
Fat embolism | 21.88 | 10.73 | 13 | 173283 | 180 | 34783455 |
Hyperthyroidism | 21.82 | 10.73 | 107 | 173189 | 10459 | 34773176 |
Purpura | 21.71 | 10.73 | 105 | 173191 | 10206 | 34773429 |
Obstructive airways disorder | 21.59 | 10.73 | 27 | 173269 | 15467 | 34768168 |
Schizophrenia | 21.52 | 10.73 | 8 | 173288 | 8658 | 34774977 |
Catheter placement | 21.44 | 10.73 | 23 | 173273 | 775 | 34782860 |
Paranoia | 21.44 | 10.73 | 17 | 173279 | 12051 | 34771584 |
Paraesthesia | 21.36 | 10.73 | 209 | 173087 | 63963 | 34719672 |
Aspartate aminotransferase increased | 21.22 | 10.73 | 224 | 173072 | 67559 | 34716076 |
Peripheral swelling | 21.20 | 10.73 | 513 | 172783 | 76028 | 34707607 |
Muscle strain | 21.15 | 10.73 | 55 | 173241 | 3921 | 34779714 |
Acute generalised exanthematous pustulosis | 21.08 | 10.73 | 4 | 173292 | 6772 | 34776863 |
Akathisia | 20.97 | 10.73 | 7 | 173289 | 8102 | 34775533 |
Haemorrhagic cholecystitis | 20.93 | 10.73 | 10 | 173286 | 86 | 34783549 |
Anticoagulation drug level increased | 20.91 | 10.73 | 19 | 173277 | 521 | 34783114 |
Mental status changes | 20.78 | 10.73 | 284 | 173012 | 37799 | 34745836 |
Labelled drug-disease interaction medication error | 20.78 | 10.73 | 11 | 173285 | 120 | 34783515 |
Hyperkalaemia | 20.73 | 10.73 | 470 | 172826 | 68919 | 34714716 |
Apallic syndrome | 20.68 | 10.73 | 14 | 173282 | 246 | 34783389 |
Congestive hepatopathy | 20.62 | 10.73 | 35 | 173261 | 1846 | 34781789 |
Psychomotor hyperactivity | 20.57 | 10.73 | 11 | 173285 | 9611 | 34774024 |
Herpes zoster | 20.56 | 10.73 | 94 | 173202 | 34305 | 34749330 |
Hepatitis | 20.54 | 10.73 | 56 | 173240 | 23848 | 34759787 |
Catheter site pain | 20.42 | 10.73 | 29 | 173267 | 1309 | 34782326 |
Withdrawal syndrome | 20.36 | 10.73 | 19 | 173277 | 12436 | 34771199 |
Intra-abdominal haemorrhage | 20.35 | 10.73 | 40 | 173256 | 2364 | 34781271 |
Hepatic failure | 20.26 | 10.73 | 95 | 173201 | 34436 | 34749199 |
Blood viscosity decreased | 20.17 | 10.73 | 9 | 173287 | 65 | 34783570 |
Adrenal insufficiency | 20.08 | 10.73 | 24 | 173272 | 14023 | 34769612 |
Hypoprothrombinaemia | 20.04 | 10.73 | 16 | 173280 | 366 | 34783269 |
Cytomegalovirus viraemia | 19.95 | 10.73 | 6 | 173290 | 7424 | 34776211 |
Large intestinal haemorrhage | 19.92 | 10.73 | 32 | 173264 | 1612 | 34782023 |
Brain herniation | 19.86 | 10.73 | 54 | 173242 | 3954 | 34779681 |
Prothrombin time shortened | 19.83 | 10.73 | 30 | 173266 | 1434 | 34782201 |
Platelet distribution width increased | 19.80 | 10.73 | 11 | 173285 | 133 | 34783502 |
Drug withdrawal syndrome | 19.77 | 10.73 | 43 | 173253 | 19791 | 34763844 |
Splenic haematoma | 19.66 | 10.73 | 12 | 173284 | 175 | 34783460 |
Pericarditis uraemic | 19.34 | 10.73 | 6 | 173290 | 12 | 34783623 |
Encephalitis | 19.32 | 10.73 | 6 | 173290 | 7271 | 34776364 |
Renal haematoma | 19.30 | 10.73 | 18 | 173278 | 511 | 34783124 |
Wheezing | 19.29 | 10.73 | 123 | 173173 | 41279 | 34742356 |
Pulmonary endarterectomy | 19.18 | 10.73 | 9 | 173287 | 74 | 34783561 |
Mitral valve replacement | 19.08 | 10.73 | 12 | 173284 | 185 | 34783450 |
Protein S deficiency | 19.05 | 10.73 | 10 | 173286 | 107 | 34783528 |
Gravitational oedema | 18.98 | 10.73 | 20 | 173276 | 660 | 34782975 |
Rash erythematous | 18.95 | 10.73 | 62 | 173234 | 24915 | 34758720 |
Central venous catheterisation | 18.94 | 10.73 | 28 | 173268 | 1311 | 34782324 |
Neurotoxicity | 18.83 | 10.73 | 38 | 173258 | 17972 | 34765663 |
No adverse event | 18.75 | 10.73 | 55 | 173241 | 22872 | 34760763 |
Anastomotic infection | 18.74 | 10.73 | 10 | 173286 | 111 | 34783524 |
Pathogen resistance | 18.63 | 10.73 | 12 | 173284 | 9470 | 34774165 |
Illness | 18.41 | 10.73 | 24 | 173272 | 13505 | 34770130 |
Obesity | 18.41 | 10.73 | 22 | 173274 | 12856 | 34770779 |
Drug-induced liver injury | 18.32 | 10.73 | 77 | 173219 | 28755 | 34754880 |
Cardiotoxicity | 18.30 | 10.73 | 3 | 173293 | 5645 | 34777990 |
Prothrombin level abnormal | 18.30 | 10.73 | 9 | 173287 | 83 | 34783552 |
Large intestinal ulcer haemorrhage | 18.28 | 10.73 | 10 | 173286 | 117 | 34783518 |
Rales | 18.25 | 10.73 | 97 | 173199 | 9786 | 34773849 |
Ventricular hyperkinesia | 18.07 | 10.73 | 12 | 173284 | 204 | 34783431 |
Transplant evaluation | 18.04 | 10.73 | 17 | 173279 | 489 | 34783146 |
Catheter removal | 18.02 | 10.73 | 12 | 173284 | 205 | 34783430 |
Medication error | 17.99 | 10.73 | 200 | 173096 | 25365 | 34758270 |
Nausea | 17.99 | 10.73 | 1446 | 171850 | 338462 | 34445173 |
Diffuse large B-cell lymphoma | 17.97 | 10.73 | 7 | 173289 | 7363 | 34776272 |
Vitamin K deficiency | 17.89 | 10.73 | 13 | 173283 | 257 | 34783378 |
Anal abscess | 17.80 | 10.73 | 5 | 173291 | 6468 | 34777167 |
Transplant rejection | 17.73 | 10.73 | 15 | 173281 | 10296 | 34773339 |
Stress | 17.67 | 10.73 | 229 | 173067 | 30118 | 34753517 |
Hepatitis B | 17.65 | 10.73 | 4 | 173292 | 5979 | 34777656 |
Tongue haematoma | 17.64 | 10.73 | 10 | 173286 | 126 | 34783509 |
Prothrombin level increased | 17.64 | 10.73 | 11 | 173285 | 167 | 34783468 |
Drug reaction with eosinophilia and systemic symptoms | 17.55 | 10.73 | 94 | 173202 | 32918 | 34750717 |
Fistula | 17.52 | 10.73 | 6 | 173290 | 6834 | 34776801 |
Pharyngeal haematoma | 17.45 | 10.73 | 8 | 173288 | 62 | 34783573 |
Influenza like illness | 17.43 | 10.73 | 74 | 173222 | 27560 | 34756075 |
Hemianopia homonymous | 17.39 | 10.73 | 20 | 173276 | 729 | 34782906 |
Heart valve replacement | 17.34 | 10.73 | 15 | 173281 | 385 | 34783250 |
Somnolence | 17.27 | 10.73 | 419 | 172877 | 110697 | 34672938 |
Tracheal calcification | 17.25 | 10.73 | 4 | 173292 | 0 | 34783635 |
Gangrene | 17.22 | 10.73 | 56 | 173240 | 4530 | 34779105 |
Haemobilia | 17.21 | 10.73 | 15 | 173281 | 389 | 34783246 |
Fear | 17.10 | 10.73 | 16 | 173280 | 10460 | 34773175 |
Palmar-plantar erythrodysaesthesia syndrome | 17.08 | 10.73 | 36 | 173260 | 16759 | 34766876 |
Hyperglycaemia | 17.03 | 10.73 | 120 | 173176 | 39360 | 34744275 |
Chest tube insertion | 17.01 | 10.73 | 9 | 173287 | 98 | 34783537 |
Blood pressure decreased | 17.00 | 10.73 | 354 | 172942 | 51161 | 34732474 |
Pneumonia fungal | 16.89 | 10.73 | 7 | 173289 | 7093 | 34776542 |
Bovine tuberculosis | 16.86 | 10.73 | 9 | 173287 | 100 | 34783535 |
Injection site reaction | 16.85 | 10.73 | 24 | 173272 | 13009 | 34770626 |
Encephalomalacia | 16.79 | 10.73 | 21 | 173275 | 837 | 34782798 |
Right ventricular diastolic collapse | 16.72 | 10.73 | 8 | 173288 | 69 | 34783566 |
Poisoning deliberate | 16.72 | 10.73 | 9 | 173287 | 7835 | 34775800 |
Dry skin | 16.68 | 10.73 | 89 | 173207 | 31198 | 34752437 |
Vomiting | 16.59 | 10.73 | 1032 | 172264 | 246589 | 34537046 |
Adenovirus infection | 16.58 | 10.73 | 3 | 173293 | 5254 | 34778381 |
Blood cholinesterase decreased | 16.55 | 10.73 | 10 | 173286 | 143 | 34783492 |
Exercise tolerance decreased | 16.48 | 10.73 | 60 | 173236 | 5138 | 34778497 |
Xanthopsia | 16.43 | 10.73 | 10 | 173286 | 145 | 34783490 |
Sleep disorder due to a general medical condition | 16.42 | 10.73 | 3 | 173293 | 5218 | 34778417 |
Glomerular filtration rate | 16.40 | 10.73 | 9 | 173287 | 106 | 34783529 |
Peptic ulcer | 16.38 | 10.73 | 40 | 173256 | 2743 | 34780892 |
Hepatic rupture | 16.37 | 10.73 | 7 | 173289 | 45 | 34783590 |
Infected skin ulcer | 16.36 | 10.73 | 29 | 173267 | 1584 | 34782051 |
Mouth ulceration | 16.34 | 10.73 | 21 | 173275 | 11889 | 34771746 |
Spinal cord haematoma | 16.33 | 10.73 | 9 | 173287 | 107 | 34783528 |
Puncture site haematoma | 16.31 | 10.73 | 10 | 173286 | 147 | 34783488 |
Craniotomy | 16.31 | 10.73 | 10 | 173286 | 147 | 34783488 |
Electrolyte imbalance | 16.30 | 10.73 | 29 | 173267 | 14383 | 34769252 |
Infusion site pain | 16.28 | 10.73 | 49 | 173247 | 3802 | 34779833 |
Device occlusion | 16.27 | 10.73 | 70 | 173226 | 6475 | 34777160 |
Aortic stenosis | 16.17 | 10.73 | 53 | 173243 | 4305 | 34779330 |
Implantable defibrillator replacement | 16.12 | 10.73 | 5 | 173291 | 10 | 34783625 |
Cardiac ventricular thrombosis | 16.04 | 10.73 | 24 | 173272 | 1136 | 34782499 |
Hypophagia | 16.04 | 10.73 | 186 | 173110 | 23836 | 34759799 |
Incarcerated hernia | 16.02 | 10.73 | 10 | 173286 | 152 | 34783483 |
Catheter site infection | 16.01 | 10.73 | 38 | 173258 | 2559 | 34781076 |
Mental disorder | 15.98 | 10.73 | 32 | 173264 | 15177 | 34768458 |
Cardiolipin antibody positive | 15.96 | 10.73 | 6 | 173290 | 26 | 34783609 |
Right atrial enlargement | 15.94 | 10.73 | 12 | 173284 | 251 | 34783384 |
Infusion site erythema | 15.94 | 10.73 | 35 | 173261 | 2238 | 34781397 |
Urinary bladder haemorrhage | 15.91 | 10.73 | 30 | 173266 | 1719 | 34781916 |
Epstein-Barr virus infection | 15.90 | 10.73 | 9 | 173287 | 7619 | 34776016 |
Tongue haemorrhage | 15.85 | 10.73 | 17 | 173279 | 573 | 34783062 |
Osteoarthritis | 15.82 | 10.73 | 51 | 173245 | 20591 | 34763044 |
Vascular calcification | 15.82 | 10.73 | 20 | 173276 | 806 | 34782829 |
Protein C decreased | 15.78 | 10.73 | 6 | 173290 | 27 | 34783608 |
Medical device site haematoma | 15.78 | 10.73 | 6 | 173290 | 27 | 34783608 |
Conjunctivitis | 15.63 | 10.73 | 15 | 173281 | 9690 | 34773945 |
Mitral valve thickening | 15.53 | 10.73 | 14 | 173282 | 380 | 34783255 |
Coagulation test abnormal | 15.52 | 10.73 | 17 | 173279 | 587 | 34783048 |
Acute respiratory distress syndrome | 15.50 | 10.73 | 71 | 173225 | 25898 | 34757737 |
Spinal cord haemorrhage | 15.48 | 10.73 | 13 | 173283 | 320 | 34783315 |
Radiation proctitis | 15.44 | 10.73 | 9 | 173287 | 120 | 34783515 |
Anaesthesia | 15.41 | 10.73 | 7 | 173289 | 53 | 34783582 |
Bronchiectasis | 15.33 | 10.73 | 92 | 173204 | 9709 | 34773926 |
Oesophageal ulcer | 15.23 | 10.73 | 44 | 173252 | 3337 | 34780298 |
Sinus node dysfunction | 15.16 | 10.73 | 51 | 173245 | 4198 | 34779437 |
Cerebellar haematoma | 15.16 | 10.73 | 11 | 173285 | 217 | 34783418 |
Gastrointestinal ulcer | 15.13 | 10.73 | 29 | 173267 | 1682 | 34781953 |
Polyneuropathy | 15.09 | 10.73 | 32 | 173264 | 14864 | 34768771 |
Cardioactive drug level increased | 15.06 | 10.73 | 29 | 173267 | 1688 | 34781947 |
Hepatic haematoma | 15.05 | 10.73 | 14 | 173282 | 396 | 34783239 |
Muscle rigidity | 15.00 | 10.73 | 18 | 173278 | 10500 | 34773135 |
Cytopenia | 14.94 | 10.73 | 25 | 173271 | 12698 | 34770937 |
Hypogammaglobulinaemia | 14.93 | 10.73 | 10 | 173286 | 7730 | 34775905 |
Periorbital haematoma | 14.92 | 10.73 | 13 | 173283 | 337 | 34783298 |
Hepatitis C | 14.92 | 10.73 | 16 | 173280 | 9814 | 34773821 |
Toxic epidermal necrolysis | 14.90 | 10.73 | 56 | 173240 | 21590 | 34762045 |
Splenic rupture | 14.73 | 10.73 | 27 | 173269 | 1514 | 34782121 |
Strangury | 14.70 | 10.73 | 9 | 173287 | 132 | 34783503 |
Gastrointestinal erosion | 14.68 | 10.73 | 14 | 173282 | 409 | 34783226 |
Heart valve operation | 14.67 | 10.73 | 7 | 173289 | 60 | 34783575 |
Blood pressure diastolic abnormal | 14.66 | 10.73 | 3 | 173293 | 4815 | 34778820 |
Injection site erythema | 14.61 | 10.73 | 36 | 173260 | 15863 | 34767772 |
Incision site haematoma | 14.60 | 10.73 | 8 | 173288 | 94 | 34783541 |
Hepatic encephalopathy | 14.50 | 10.73 | 32 | 173264 | 14653 | 34768982 |
Syringe issue | 14.45 | 10.73 | 5 | 173291 | 5659 | 34777976 |
Brain natriuretic peptide increased | 14.44 | 10.73 | 61 | 173235 | 5598 | 34778037 |
Neutropenic sepsis | 14.43 | 10.73 | 29 | 173267 | 13738 | 34769897 |
Blood urea increased | 14.41 | 10.73 | 221 | 173075 | 30143 | 34753492 |
Pulmonary haematoma | 14.38 | 10.73 | 7 | 173289 | 63 | 34783572 |
Euphoric mood | 14.36 | 10.73 | 5 | 173291 | 5636 | 34777999 |
Eye haematoma | 14.28 | 10.73 | 7 | 173289 | 64 | 34783571 |
N-telopeptide urine increased | 14.24 | 10.73 | 6 | 173290 | 37 | 34783598 |
Blood uric acid increased | 14.21 | 10.73 | 89 | 173207 | 9535 | 34774100 |
Jugular vein distension | 14.16 | 10.73 | 17 | 173279 | 649 | 34782986 |
Procedural site reaction | 14.10 | 10.73 | 10 | 173286 | 190 | 34783445 |
Feeling hot | 14.07 | 10.73 | 49 | 173247 | 19323 | 34764312 |
Respiratory depression | 14.00 | 10.73 | 38 | 173258 | 16207 | 34767428 |
Transaminases increased | 13.91 | 10.73 | 77 | 173219 | 26746 | 34756889 |
Muscle spasms | 13.89 | 10.73 | 275 | 173021 | 74726 | 34708909 |
Disease recurrence | 13.89 | 10.73 | 57 | 173239 | 21433 | 34762202 |
Cerebral infarction | 13.88 | 10.73 | 202 | 173094 | 27253 | 34756382 |
Antiphospholipid antibodies positive | 13.87 | 10.73 | 12 | 173284 | 308 | 34783327 |
Oesophageal ulcer haemorrhage | 13.84 | 10.73 | 10 | 173286 | 196 | 34783439 |
Tumour haemorrhage | 13.78 | 10.73 | 39 | 173257 | 2923 | 34780712 |
Vascular pseudoaneurysm | 13.67 | 10.73 | 32 | 173264 | 2135 | 34781500 |
Arteriovenous fistula site haemorrhage | 13.64 | 10.73 | 8 | 173288 | 108 | 34783527 |
Gastrointestinal angiodysplasia | 13.62 | 10.73 | 16 | 173280 | 597 | 34783038 |
Protein C deficiency | 13.61 | 10.73 | 4 | 173292 | 6 | 34783629 |
Panic attack | 13.60 | 10.73 | 16 | 173280 | 9416 | 34774219 |
Crying | 13.60 | 10.73 | 6 | 173290 | 5856 | 34777779 |
Catatonia | 13.60 | 10.73 | 4 | 173292 | 5021 | 34778614 |
Concomitant disease progression | 13.57 | 10.73 | 35 | 173261 | 2483 | 34781152 |
Weight decreased | 13.56 | 10.73 | 725 | 172571 | 175576 | 34608059 |
Lipase increased | 13.55 | 10.73 | 16 | 173280 | 9400 | 34774235 |
Cardiac valve disease | 13.49 | 10.73 | 40 | 173256 | 3078 | 34780557 |
Large intestine polyp | 13.49 | 10.73 | 76 | 173220 | 7838 | 34775797 |
Ascites | 13.46 | 10.73 | 314 | 172982 | 46257 | 34737378 |
Spinal osteoarthritis | 13.43 | 10.73 | 11 | 173285 | 7672 | 34775963 |
Incision site haemorrhage | 13.41 | 10.73 | 15 | 173281 | 530 | 34783105 |
Endarterectomy | 13.40 | 10.73 | 9 | 173287 | 156 | 34783479 |
Diarrhoea | 13.28 | 10.73 | 1712 | 171584 | 388200 | 34395435 |
Haemorrhagic infarction | 13.26 | 10.73 | 14 | 173282 | 463 | 34783172 |
Ulnar nerve palsy | 13.24 | 10.73 | 4 | 173292 | 7 | 34783628 |
Night sweats | 13.21 | 10.73 | 43 | 173253 | 17309 | 34766326 |
Erectile dysfunction | 13.18 | 10.73 | 55 | 173241 | 20582 | 34763053 |
Hyperthermia | 13.16 | 10.73 | 20 | 173276 | 10557 | 34773078 |
Cardiac disorder | 13.15 | 10.73 | 293 | 173003 | 42833 | 34740802 |
Maternal exposure during pregnancy | 13.15 | 10.73 | 4 | 173292 | 4914 | 34778721 |
Eye haemorrhage | 13.07 | 10.73 | 49 | 173247 | 4256 | 34779379 |
Proctalgia | 13.05 | 10.73 | 6 | 173290 | 5717 | 34777918 |
Femoral artery aneurysm | 13.02 | 10.73 | 9 | 173287 | 164 | 34783471 |
Acute cutaneous lupus erythematosus | 13.02 | 10.73 | 7 | 173289 | 79 | 34783556 |
Increased tendency to bruise | 12.98 | 10.73 | 47 | 173249 | 4014 | 34779621 |
Cognitive disorder | 12.98 | 10.73 | 86 | 173210 | 28607 | 34755028 |
Frequent bowel movements | 12.94 | 10.73 | 108 | 173188 | 12679 | 34770956 |
Eye infection intraocular | 12.94 | 10.73 | 3 | 173293 | 0 | 34783635 |
Arteriovenous graft site haemorrhage | 12.94 | 10.73 | 3 | 173293 | 0 | 34783635 |
Vascular fragility | 12.94 | 10.73 | 3 | 173293 | 0 | 34783635 |
Cardiolipin antibody | 12.94 | 10.73 | 3 | 173293 | 0 | 34783635 |
Delusion | 12.92 | 10.73 | 27 | 173269 | 12608 | 34771027 |
Cor pulmonale | 12.92 | 10.73 | 18 | 173278 | 798 | 34782837 |
Erythema | 12.92 | 10.73 | 338 | 172958 | 88442 | 34695193 |
Uveitis | 12.91 | 10.73 | 11 | 173285 | 7524 | 34776111 |
Aortic valve replacement | 12.83 | 10.73 | 18 | 173278 | 803 | 34782832 |
Klebsiella infection | 12.82 | 10.73 | 14 | 173282 | 8517 | 34775118 |
Basal cell carcinoma | 12.80 | 10.73 | 52 | 173244 | 19606 | 34764029 |
Impaired quality of life | 12.80 | 10.73 | 60 | 173236 | 5758 | 34777877 |
Pulmonary calcification | 12.74 | 10.73 | 10 | 173286 | 223 | 34783412 |
Blood pressure systolic decreased | 12.65 | 10.73 | 50 | 173246 | 4453 | 34779182 |
Pulmonary haemorrhage | 12.63 | 10.73 | 91 | 173205 | 10213 | 34773422 |
Hypertransaminasaemia | 12.60 | 10.73 | 6 | 173290 | 5600 | 34778035 |
Upper airway obstruction | 12.57 | 10.73 | 16 | 173280 | 649 | 34782986 |
Product storage error | 12.57 | 10.73 | 13 | 173283 | 8109 | 34775526 |
Agranulocytosis | 12.57 | 10.73 | 68 | 173228 | 23753 | 34759882 |
Subdural haematoma evacuation | 12.57 | 10.73 | 5 | 173291 | 26 | 34783609 |
Walking distance test abnormal | 12.56 | 10.73 | 9 | 173287 | 174 | 34783461 |
Myocarditis | 12.56 | 10.73 | 31 | 173265 | 13651 | 34769984 |
Skin lesion | 12.54 | 10.73 | 61 | 173235 | 21900 | 34761735 |
Infusion site warmth | 12.52 | 10.73 | 8 | 173288 | 127 | 34783508 |
Hypercholesterolaemia | 12.49 | 10.73 | 15 | 173281 | 8747 | 34774888 |
Brain stem haemorrhage | 12.49 | 10.73 | 19 | 173277 | 913 | 34782722 |
Ankle deformity | 12.44 | 10.73 | 10 | 173286 | 231 | 34783404 |
Orthostatic hypotension | 12.43 | 10.73 | 189 | 173107 | 25730 | 34757905 |
Paracentesis | 12.39 | 10.73 | 13 | 173283 | 427 | 34783208 |
Prothrombin level decreased | 12.38 | 10.73 | 21 | 173275 | 1107 | 34782528 |
Thrombotic microangiopathy | 12.38 | 10.73 | 21 | 173275 | 10609 | 34773026 |
Oesophageal pain | 12.37 | 10.73 | 18 | 173278 | 831 | 34782804 |
Burns second degree | 12.37 | 10.73 | 21 | 173275 | 1108 | 34782527 |
Cellulitis | 12.36 | 10.73 | 347 | 172949 | 52604 | 34731031 |
Emotional distress | 12.32 | 10.73 | 36 | 173260 | 14990 | 34768645 |
Elbow operation | 12.30 | 10.73 | 8 | 173288 | 131 | 34783504 |
Hydrocephalus | 12.28 | 10.73 | 55 | 173241 | 5177 | 34778458 |
Libido decreased | 12.24 | 10.73 | 4 | 173292 | 4692 | 34778943 |
Cardiac pacemaker replacement | 12.21 | 10.73 | 9 | 173287 | 182 | 34783453 |
Encephalopathy | 12.18 | 10.73 | 114 | 173182 | 35205 | 34748430 |
Thrombectomy | 12.16 | 10.73 | 7 | 173289 | 91 | 34783544 |
Femoral nerve palsy | 12.14 | 10.73 | 6 | 173290 | 56 | 34783579 |
Mean platelet volume increased | 12.05 | 10.73 | 14 | 173282 | 516 | 34783119 |
Presyncope | 12.03 | 10.73 | 146 | 173150 | 18913 | 34764722 |
Aortic bruit | 12.02 | 10.73 | 10 | 173286 | 243 | 34783392 |
Tricuspid valve replacement | 11.98 | 10.73 | 5 | 173291 | 30 | 34783605 |
Inappropriate schedule of product administration | 11.97 | 10.73 | 227 | 173069 | 62069 | 34721566 |
Catheter site swelling | 11.95 | 10.73 | 12 | 173284 | 374 | 34783261 |
Gout | 11.94 | 10.73 | 147 | 173149 | 19106 | 34764529 |
Hypocalcaemia | 11.91 | 10.73 | 71 | 173225 | 24218 | 34759417 |
Refusal of treatment by patient | 11.89 | 10.73 | 53 | 173243 | 4979 | 34778656 |
Pulmonary arterial pressure increased | 11.88 | 10.73 | 22 | 173274 | 1243 | 34782392 |
Heartland virus infection | 11.84 | 10.73 | 5 | 173291 | 31 | 34783604 |
Coagulation factor V level increased | 11.84 | 10.73 | 5 | 173291 | 31 | 34783604 |
Aplasia | 11.79 | 10.73 | 4 | 173292 | 4584 | 34779051 |
Vitreous haemorrhage | 11.79 | 10.73 | 32 | 173264 | 2341 | 34781294 |
Aphthous ulcer | 11.76 | 10.73 | 5 | 173291 | 4990 | 34778645 |
Ubiquinone decreased | 11.76 | 10.73 | 4 | 173292 | 12 | 34783623 |
Procalcitonin | 11.76 | 10.73 | 4 | 173292 | 12 | 34783623 |
Lymphoma | 11.75 | 10.73 | 28 | 173268 | 12479 | 34771156 |
Cardiac ventricular disorder | 11.74 | 10.73 | 10 | 173286 | 251 | 34783384 |
Cardioactive drug level above therapeutic | 11.70 | 10.73 | 6 | 173290 | 61 | 34783574 |
Haemorrhoids | 11.65 | 10.73 | 117 | 173179 | 14458 | 34769177 |
Blood potassium increased | 11.59 | 10.73 | 129 | 173167 | 16366 | 34767269 |
Cardiac pseudoaneurysm | 11.58 | 10.73 | 5 | 173291 | 33 | 34783602 |
Metastatic carcinoid tumour | 11.52 | 10.73 | 4 | 173292 | 13 | 34783622 |
Disorientation | 11.50 | 10.73 | 107 | 173189 | 33081 | 34750554 |
Infusion site haemorrhage | 11.43 | 10.73 | 19 | 173277 | 985 | 34782650 |
Cystitis haemorrhagic | 11.41 | 10.73 | 7 | 173289 | 5672 | 34777963 |
Burning feet syndrome | 11.41 | 10.73 | 7 | 173289 | 103 | 34783532 |
Pseudomonas infection | 11.41 | 10.73 | 28 | 173268 | 12354 | 34771281 |
Muscle twitching | 11.40 | 10.73 | 21 | 173275 | 10277 | 34773358 |
Hemiparesis | 11.36 | 10.73 | 124 | 173172 | 15654 | 34767981 |
Bradyarrhythmia | 11.34 | 10.73 | 30 | 173266 | 2161 | 34781474 |
Antiphospholipid antibodies | 11.30 | 10.73 | 4 | 173292 | 14 | 34783621 |
Left ventricular failure | 11.28 | 10.73 | 53 | 173243 | 5091 | 34778544 |
Post procedural haematoma | 11.27 | 10.73 | 24 | 173272 | 1502 | 34782133 |
Bladder cancer | 11.27 | 10.73 | 42 | 173254 | 16236 | 34767399 |
Hyperammonaemia | 11.27 | 10.73 | 9 | 173287 | 6358 | 34777277 |
Wound haemorrhage | 11.26 | 10.73 | 29 | 173267 | 2056 | 34781579 |
Atrial septal defect | 11.25 | 10.73 | 12 | 173284 | 7380 | 34776255 |
Atrial septal defect repair | 11.24 | 10.73 | 7 | 173289 | 106 | 34783529 |
Therapeutic procedure | 11.23 | 10.73 | 9 | 173287 | 207 | 34783428 |
Throat tightness | 11.20 | 10.73 | 15 | 173281 | 8343 | 34775292 |
Therapeutic response increased | 11.14 | 10.73 | 10 | 173286 | 270 | 34783365 |
Procedural haemorrhage | 11.09 | 10.73 | 32 | 173264 | 2425 | 34781210 |
Salivary hypersecretion | 11.09 | 10.73 | 16 | 173280 | 8628 | 34775007 |
Mood altered | 11.07 | 10.73 | 17 | 173279 | 8935 | 34774700 |
Normocytic anaemia | 11.04 | 10.73 | 31 | 173265 | 2313 | 34781322 |
Protein-losing gastroenteropathy | 10.95 | 10.73 | 11 | 173285 | 343 | 34783292 |
Heart transplant | 10.94 | 10.73 | 18 | 173278 | 925 | 34782710 |
Wound decomposition | 10.91 | 10.73 | 6 | 173290 | 71 | 34783564 |
Tuberculosis | 10.88 | 10.73 | 16 | 173280 | 8561 | 34775074 |
Epiphyseal disorder | 10.87 | 10.73 | 3 | 173293 | 3 | 34783632 |
Breast haematoma | 10.87 | 10.73 | 3 | 173293 | 3 | 34783632 |
Alkalosis hypokalaemic | 10.87 | 10.73 | 3 | 173293 | 3 | 34783632 |
Atelectasis | 10.86 | 10.73 | 48 | 173248 | 17679 | 34765956 |
Nephrolithiasis | 10.86 | 10.73 | 97 | 173199 | 30236 | 34753399 |
Aneurysm ruptured | 10.79 | 10.73 | 13 | 173283 | 498 | 34783137 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
International normalised ratio increased | 18570.57 | 9.93 | 8295 | 314616 | 76426 | 79345051 |
Haemorrhage | 2389.02 | 9.93 | 2357 | 320554 | 88761 | 79332716 |
International normalised ratio abnormal | 2211.65 | 9.93 | 845 | 322066 | 4923 | 79416554 |
Gastric haemorrhage | 2075.82 | 9.93 | 1076 | 321835 | 13974 | 79407503 |
Drug interaction | 2015.32 | 9.93 | 4878 | 318033 | 410305 | 79011172 |
International normalised ratio decreased | 1795.12 | 9.93 | 801 | 322110 | 7269 | 79414208 |
Gastrointestinal haemorrhage | 1653.46 | 9.93 | 2482 | 320429 | 145237 | 79276240 |
Anticoagulation drug level above therapeutic | 1608.98 | 9.93 | 591 | 322320 | 3029 | 79418448 |
Calciphylaxis | 1239.22 | 9.93 | 494 | 322417 | 3276 | 79418201 |
Subdural haematoma | 1220.86 | 9.93 | 1015 | 321896 | 30419 | 79391058 |
Haematoma | 1218.71 | 9.93 | 1269 | 321642 | 50926 | 79370551 |
Melaena | 999.69 | 9.93 | 1233 | 321678 | 59657 | 79361820 |
Haematuria | 985.24 | 9.93 | 1302 | 321609 | 67534 | 79353943 |
Epistaxis | 938.00 | 9.93 | 1647 | 321264 | 109868 | 79311609 |
Drug ineffective | 895.98 | 9.93 | 1906 | 321005 | 1079007 | 78342470 |
Haemorrhage intracranial | 859.19 | 9.93 | 768 | 322143 | 25425 | 79396052 |
Pulmonary arterial hypertension | 848.92 | 9.93 | 790 | 322121 | 27576 | 79393901 |
Labelled drug-drug interaction medication error | 710.26 | 9.93 | 708 | 322203 | 26942 | 79394535 |
Anticoagulation drug level below therapeutic | 698.75 | 9.93 | 255 | 322656 | 1278 | 79420199 |
Cerebral haemorrhage | 685.95 | 9.93 | 998 | 321913 | 56675 | 79364802 |
Haemoglobin decreased | 680.67 | 9.93 | 2212 | 320699 | 219907 | 79201570 |
Cardiac failure congestive | 670.51 | 9.93 | 1657 | 321254 | 140745 | 79280732 |
Fluid retention | 655.33 | 9.93 | 1083 | 321828 | 68726 | 79352751 |
Anaemia | 632.70 | 9.93 | 3504 | 319407 | 441511 | 78979966 |
Off label use | 594.28 | 9.93 | 1801 | 321110 | 905414 | 78516063 |
Prothrombin time prolonged | 589.16 | 9.93 | 513 | 322398 | 16386 | 79405091 |
International normalised ratio fluctuation | 579.18 | 9.93 | 282 | 322629 | 3172 | 79418305 |
Rectal haemorrhage | 578.99 | 9.93 | 1078 | 321833 | 75222 | 79346255 |
Dyspnoea | 567.34 | 9.93 | 5621 | 317290 | 851404 | 78570073 |
Synovitis | 555.75 | 9.93 | 11 | 322900 | 150723 | 79270754 |
Coagulopathy | 485.84 | 9.93 | 662 | 322249 | 35344 | 79386133 |
Haemoptysis | 479.49 | 9.93 | 834 | 322077 | 55165 | 79366312 |
Cardiac failure | 471.22 | 9.93 | 1539 | 321372 | 153303 | 79268174 |
Pulmonary hypertension | 459.37 | 9.93 | 752 | 322159 | 47328 | 79374149 |
Infusion related reaction | 458.79 | 9.93 | 179 | 322732 | 230058 | 79191419 |
Drug intolerance | 439.99 | 9.93 | 262 | 322649 | 263857 | 79157620 |
Atrial fibrillation | 437.07 | 9.93 | 1772 | 321139 | 196114 | 79225363 |
Febrile neutropenia | 427.70 | 9.93 | 200 | 322711 | 230799 | 79190678 |
Abdominal wall haematoma | 425.06 | 9.93 | 258 | 322653 | 4615 | 79416862 |
Right ventricular failure | 410.13 | 9.93 | 491 | 322420 | 23006 | 79398471 |
Muscle haemorrhage | 402.09 | 9.93 | 274 | 322637 | 6026 | 79415451 |
Pemphigus | 385.79 | 9.93 | 3 | 322908 | 99579 | 79321898 |
Pain in jaw | 385.56 | 9.93 | 680 | 322231 | 45471 | 79376006 |
Rheumatoid arthritis | 361.15 | 9.93 | 197 | 322714 | 208273 | 79213204 |
Hypervolaemia | 350.17 | 9.93 | 624 | 322287 | 42066 | 79379411 |
Joint swelling | 347.32 | 9.93 | 394 | 322517 | 288252 | 79133225 |
Therapeutic product effect decreased | 340.50 | 9.93 | 119 | 322792 | 163744 | 79257733 |
Catheter site erythema | 334.67 | 9.93 | 228 | 322683 | 5012 | 79416465 |
Arthralgia | 333.95 | 9.93 | 1192 | 321719 | 570611 | 78850866 |
Alopecia | 325.44 | 9.93 | 275 | 322636 | 231080 | 79190397 |
Upper gastrointestinal haemorrhage | 311.74 | 9.93 | 583 | 322328 | 40797 | 79380680 |
Ecchymosis | 309.52 | 9.93 | 344 | 322567 | 14862 | 79406615 |
Hand deformity | 309.18 | 9.93 | 31 | 322880 | 103888 | 79317589 |
Transfusion | 302.72 | 9.93 | 402 | 322509 | 20928 | 79400549 |
Retroperitoneal haematoma | 299.77 | 9.93 | 214 | 322697 | 5083 | 79416394 |
Drug hypersensitivity | 296.65 | 9.93 | 470 | 322441 | 298446 | 79123031 |
Fall | 294.18 | 9.93 | 3142 | 319769 | 484487 | 78936990 |
Treatment failure | 283.94 | 9.93 | 169 | 322742 | 170317 | 79251160 |
Dyspnoea exertional | 281.56 | 9.93 | 884 | 322027 | 86189 | 79335288 |
Drug abuse | 274.16 | 9.93 | 159 | 322752 | 162532 | 79258945 |
Arthropathy | 269.96 | 9.93 | 194 | 322717 | 176917 | 79244560 |
Faeces discoloured | 269.34 | 9.93 | 449 | 322462 | 28678 | 79392799 |
Hypersensitivity | 269.11 | 9.93 | 403 | 322508 | 261836 | 79159641 |
Glossodynia | 266.72 | 9.93 | 48 | 322863 | 103289 | 79318188 |
Subarachnoid haemorrhage | 258.87 | 9.93 | 401 | 322510 | 24064 | 79397413 |
Musculoskeletal stiffness | 257.32 | 9.93 | 199 | 322712 | 174809 | 79246668 |
Pain | 255.31 | 9.93 | 1736 | 321175 | 702066 | 78719411 |
Thrombosis | 253.92 | 9.93 | 834 | 322077 | 83266 | 79338211 |
Subdural haemorrhage | 253.85 | 9.93 | 203 | 322708 | 5745 | 79415732 |
Neutropenia | 247.90 | 9.93 | 494 | 322417 | 287216 | 79134261 |
Stomatitis | 246.46 | 9.93 | 144 | 322767 | 146613 | 79274864 |
Contraindicated product administered | 244.78 | 9.93 | 169 | 322742 | 157369 | 79264108 |
Pericarditis | 243.29 | 9.93 | 61 | 322850 | 104175 | 79317302 |
Catheter site pain | 242.83 | 9.93 | 190 | 322721 | 5206 | 79416271 |
Hepatic enzyme increased | 233.17 | 9.93 | 237 | 322674 | 182373 | 79239104 |
Device related infection | 232.37 | 9.93 | 462 | 322449 | 33832 | 79387645 |
Product use in unapproved indication | 232.28 | 9.93 | 411 | 322500 | 249948 | 79171529 |
Catheter management | 230.66 | 9.93 | 158 | 322753 | 3505 | 79417972 |
Oedema peripheral | 228.05 | 9.93 | 1775 | 321136 | 250513 | 79170964 |
Retroperitoneal haemorrhage | 217.22 | 9.93 | 179 | 322732 | 5291 | 79416186 |
Coagulation time prolonged | 214.80 | 9.93 | 131 | 322780 | 2364 | 79419113 |
Duodenal ulcer perforation | 212.88 | 9.93 | 14 | 322897 | 66197 | 79355280 |
Syncope | 212.23 | 9.93 | 1348 | 321563 | 178101 | 79243376 |
Haematemesis | 211.56 | 9.93 | 575 | 322336 | 51689 | 79369788 |
Rash | 209.81 | 9.93 | 1426 | 321485 | 576932 | 78844545 |
Haematocrit decreased | 207.96 | 9.93 | 633 | 322278 | 60679 | 79360798 |
Product use issue | 207.02 | 9.93 | 331 | 322580 | 209491 | 79211986 |
Therapeutic product effect incomplete | 204.50 | 9.93 | 164 | 322747 | 141481 | 79279996 |
Catheter site discharge | 203.45 | 9.93 | 125 | 322786 | 2287 | 79419190 |
Hypotension | 196.00 | 9.93 | 2679 | 320232 | 437638 | 78983839 |
Pyrexia | 190.95 | 9.93 | 1793 | 321118 | 676916 | 78744561 |
Heparin-induced thrombocytopenia | 190.15 | 9.93 | 215 | 322696 | 9467 | 79412010 |
Folliculitis | 189.66 | 9.93 | 8 | 322903 | 55372 | 79366105 |
Helicobacter infection | 189.66 | 9.93 | 28 | 322883 | 69676 | 79351801 |
Discomfort | 186.97 | 9.93 | 141 | 322770 | 125476 | 79296001 |
Lower gastrointestinal haemorrhage | 182.90 | 9.93 | 273 | 322638 | 15852 | 79405625 |
Intraventricular haemorrhage | 179.75 | 9.93 | 153 | 322758 | 4734 | 79416743 |
Haemarthrosis | 177.95 | 9.93 | 164 | 322747 | 5648 | 79415829 |
Psoriatic arthropathy | 177.52 | 9.93 | 48 | 322863 | 77951 | 79343526 |
Catheter site pruritus | 176.28 | 9.93 | 112 | 322799 | 2179 | 79419298 |
Intra-abdominal haematoma | 171.01 | 9.93 | 120 | 322791 | 2771 | 79418706 |
Central venous catheterisation | 170.48 | 9.93 | 126 | 322785 | 3163 | 79418314 |
Catheter site haemorrhage | 169.66 | 9.93 | 151 | 322760 | 4966 | 79416511 |
Systemic lupus erythematosus | 169.03 | 9.93 | 145 | 322766 | 121004 | 79300473 |
Shock haemorrhagic | 162.91 | 9.93 | 292 | 322619 | 19768 | 79401709 |
Catheter site infection | 161.69 | 9.93 | 167 | 322744 | 6628 | 79414849 |
Device alarm issue | 157.94 | 9.93 | 101 | 322810 | 1988 | 79419489 |
Wound | 156.14 | 9.93 | 144 | 322767 | 116035 | 79305442 |
Oedema | 155.65 | 9.93 | 921 | 321990 | 118659 | 79302818 |
Blood loss anaemia | 155.60 | 9.93 | 248 | 322663 | 15250 | 79406227 |
Sinusitis | 155.47 | 9.93 | 351 | 322560 | 195150 | 79226327 |
Deep vein thrombosis | 155.27 | 9.93 | 928 | 321983 | 119991 | 79301486 |
Haematoma muscle | 153.41 | 9.93 | 108 | 322803 | 2507 | 79418970 |
Completed suicide | 152.79 | 9.93 | 498 | 322413 | 245269 | 79176208 |
Skin necrosis | 151.66 | 9.93 | 267 | 322644 | 17820 | 79403657 |
COVID-19 | 150.58 | 9.93 | 254 | 322657 | 157420 | 79264057 |
Sleep disorder due to general medical condition, insomnia type | 150.13 | 9.93 | 6 | 322905 | 43550 | 79377927 |
Mucosal inflammation | 150.02 | 9.93 | 59 | 322852 | 75521 | 79345956 |
Irritable bowel syndrome | 150.00 | 9.93 | 34 | 322877 | 62207 | 79359270 |
Maternal exposure during pregnancy | 149.71 | 9.93 | 200 | 322711 | 136338 | 79285139 |
Cerebrovascular accident | 148.82 | 9.93 | 1108 | 321803 | 154184 | 79267293 |
Head injury | 147.12 | 9.93 | 407 | 322504 | 36962 | 79384515 |
Intentional overdose | 145.17 | 9.93 | 129 | 322782 | 105831 | 79315646 |
Thrombosis in device | 140.91 | 9.93 | 140 | 322771 | 5302 | 79416175 |
Depression | 139.85 | 9.93 | 432 | 322479 | 216358 | 79205119 |
Exposure during pregnancy | 138.70 | 9.93 | 123 | 322788 | 101009 | 79320468 |
Pruritus | 134.58 | 9.93 | 990 | 321921 | 393658 | 79027819 |
Malignant neoplasm progression | 134.58 | 9.93 | 214 | 322697 | 135776 | 79285701 |
Leukopenia | 132.55 | 9.93 | 166 | 322745 | 116347 | 79305130 |
Catheter placement | 132.27 | 9.93 | 104 | 322807 | 2870 | 79418607 |
Hypertension | 131.05 | 9.93 | 794 | 322117 | 330198 | 79091279 |
Muscle injury | 128.71 | 9.93 | 21 | 322890 | 48540 | 79372937 |
Activated partial thromboplastin time prolonged | 128.42 | 9.93 | 217 | 322694 | 14011 | 79407466 |
Spinal epidural haematoma | 127.94 | 9.93 | 77 | 322834 | 1355 | 79420122 |
Urticaria | 126.71 | 9.93 | 359 | 322552 | 184842 | 79236635 |
Occult blood positive | 125.33 | 9.93 | 147 | 322764 | 6736 | 79414741 |
Injection site pain | 123.19 | 9.93 | 210 | 322701 | 129628 | 79291849 |
Anaphylactic reaction | 119.54 | 9.93 | 98 | 322813 | 83645 | 79337832 |
Asthma | 118.79 | 9.93 | 229 | 322682 | 134866 | 79286611 |
Haemorrhagic stroke | 118.18 | 9.93 | 182 | 322729 | 10864 | 79410613 |
Post procedural haemorrhage | 116.68 | 9.93 | 204 | 322707 | 13540 | 79407937 |
Catheter site swelling | 116.57 | 9.93 | 80 | 322831 | 1780 | 79419697 |
Infection | 115.55 | 9.93 | 544 | 322367 | 241168 | 79180309 |
Infusion site pain | 114.66 | 9.93 | 206 | 322705 | 13970 | 79407507 |
Cytokine release syndrome | 114.58 | 9.93 | 8 | 322903 | 35990 | 79385487 |
Intentional product use issue | 113.03 | 9.93 | 283 | 322628 | 151829 | 79269648 |
Atrial flutter | 112.75 | 9.93 | 262 | 322649 | 21363 | 79400114 |
General physical health deterioration | 112.22 | 9.93 | 654 | 322257 | 274584 | 79146893 |
Anticoagulant-related nephropathy | 111.89 | 9.93 | 31 | 322880 | 46 | 79421431 |
Paraesthesia | 109.74 | 9.93 | 357 | 322554 | 175966 | 79245511 |
Intestinal haematoma | 108.59 | 9.93 | 39 | 322872 | 185 | 79421292 |
Blister | 108.14 | 9.93 | 199 | 322712 | 119277 | 79302200 |
Haemoperitoneum | 107.44 | 9.93 | 109 | 322802 | 4234 | 79417243 |
Haemorrhage subcutaneous | 106.94 | 9.93 | 114 | 322797 | 4695 | 79416782 |
Fibromyalgia | 106.75 | 9.93 | 64 | 322847 | 64276 | 79357201 |
Dizziness | 106.36 | 9.93 | 2837 | 320074 | 523604 | 78897873 |
Injection site reaction | 105.10 | 9.93 | 45 | 322866 | 54740 | 79366737 |
Gingival bleeding | 103.98 | 9.93 | 214 | 322697 | 16062 | 79405415 |
Osteoarthritis | 103.97 | 9.93 | 120 | 322791 | 87189 | 79334288 |
Myelosuppression | 103.35 | 9.93 | 19 | 322892 | 40277 | 79381200 |
Appendicolith | 101.63 | 9.93 | 148 | 322763 | 8403 | 79413074 |
Complication associated with device | 101.30 | 9.93 | 221 | 322690 | 17275 | 79404202 |
Cerebral mass effect | 101.00 | 9.93 | 74 | 322837 | 1832 | 79419645 |
Impaired healing | 100.62 | 9.93 | 124 | 322787 | 87531 | 79333946 |
Cardiac pacemaker insertion | 100.50 | 9.93 | 121 | 322790 | 5701 | 79415776 |
Inflammation | 100.07 | 9.93 | 140 | 322771 | 93613 | 79327864 |
Ventricular tachycardia | 99.21 | 9.93 | 384 | 322527 | 41551 | 79379926 |
Psoriasis | 98.42 | 9.93 | 131 | 322780 | 89456 | 79332021 |
Spontaneous haematoma | 98.31 | 9.93 | 65 | 322846 | 1357 | 79420120 |
Blood cholesterol increased | 96.56 | 9.93 | 118 | 322793 | 83602 | 79337875 |
Injection site erythema | 95.81 | 9.93 | 105 | 322806 | 78092 | 79343385 |
Extradural haematoma | 95.61 | 9.93 | 85 | 322826 | 2791 | 79418686 |
Lower respiratory tract infection | 93.99 | 9.93 | 243 | 322668 | 128977 | 79292500 |
Cardiogenic shock | 92.87 | 9.93 | 376 | 322535 | 41538 | 79379939 |
Subcutaneous haematoma | 92.17 | 9.93 | 82 | 322829 | 2695 | 79418782 |
Suicidal ideation | 90.81 | 9.93 | 105 | 322806 | 76235 | 79345242 |
Lung transplant | 90.79 | 9.93 | 102 | 322809 | 4459 | 79417018 |
Type 2 diabetes mellitus | 90.39 | 9.93 | 60 | 322851 | 57062 | 79364415 |
Palpitations | 90.08 | 9.93 | 845 | 322066 | 125765 | 79295712 |
C-reactive protein increased | 89.79 | 9.93 | 248 | 322663 | 128779 | 79292698 |
Sleep disorder | 89.40 | 9.93 | 130 | 322781 | 85547 | 79335930 |
Device leakage | 89.40 | 9.93 | 159 | 322752 | 10697 | 79410780 |
Drug dependence | 89.23 | 9.93 | 27 | 322884 | 40742 | 79380735 |
Traumatic haematoma | 88.90 | 9.93 | 71 | 322840 | 2005 | 79419472 |
Cerebellar haemorrhage | 88.63 | 9.93 | 82 | 322829 | 2838 | 79418639 |
Prothrombin time ratio increased | 87.92 | 9.93 | 36 | 322875 | 258 | 79421219 |
Hospitalisation | 87.76 | 9.93 | 668 | 322243 | 93568 | 79327909 |
Pancytopenia | 87.69 | 9.93 | 359 | 322552 | 165386 | 79256091 |
Infusion site infection | 87.34 | 9.93 | 66 | 322845 | 1715 | 79419762 |
Ill-defined disorder | 86.90 | 9.93 | 83 | 322828 | 65792 | 79355685 |
Death | 86.11 | 9.93 | 2948 | 319963 | 563566 | 78857911 |
Pulmonary alveolar haemorrhage | 84.50 | 9.93 | 160 | 322751 | 11297 | 79410180 |
Presyncope | 84.46 | 9.93 | 360 | 322551 | 40694 | 79380783 |
Bradycardia | 84.43 | 9.93 | 880 | 322031 | 134677 | 79286800 |
Neutrophil count decreased | 83.70 | 9.93 | 158 | 322753 | 93801 | 79327676 |
Suicide attempt | 83.46 | 9.93 | 129 | 322782 | 82803 | 79338674 |
Toxicity to various agents | 83.43 | 9.93 | 1203 | 321708 | 420337 | 79001140 |
Pulmonary embolism | 82.60 | 9.93 | 1060 | 321851 | 170594 | 79250883 |
Hypoaesthesia | 81.42 | 9.93 | 411 | 322500 | 178941 | 79242536 |
Blood pressure decreased | 80.60 | 9.93 | 683 | 322228 | 98783 | 79322694 |
Anxiety | 80.08 | 9.93 | 633 | 322278 | 247879 | 79173598 |
Asthenia | 78.30 | 9.93 | 2665 | 320246 | 509024 | 78912453 |
Ear haemorrhage | 78.25 | 9.93 | 67 | 322844 | 2090 | 79419387 |
Intra-abdominal haemorrhage | 77.78 | 9.93 | 94 | 322817 | 4446 | 79417031 |
Coagulation test abnormal | 77.63 | 9.93 | 55 | 322856 | 1290 | 79420187 |
Device occlusion | 76.96 | 9.93 | 157 | 322754 | 11709 | 79409768 |
Contusion | 76.41 | 9.93 | 930 | 321981 | 147846 | 79273631 |
Multiple sclerosis relapse | 76.20 | 9.93 | 47 | 322864 | 46486 | 79374991 |
Catheter site inflammation | 76.09 | 9.93 | 51 | 322860 | 1090 | 79420387 |
Hypercoagulation | 75.51 | 9.93 | 76 | 322835 | 2924 | 79418553 |
Cardiac tamponade | 75.28 | 9.93 | 135 | 322776 | 9141 | 79412336 |
Injection site pruritus | 74.55 | 9.93 | 39 | 322872 | 42244 | 79379233 |
Cardiac failure chronic | 74.21 | 9.93 | 149 | 322762 | 10986 | 79410491 |
Pericardial haemorrhage | 73.66 | 9.93 | 91 | 322820 | 4404 | 79417073 |
Internal haemorrhage | 73.55 | 9.93 | 130 | 322781 | 8703 | 79412774 |
Hypocoagulable state | 72.15 | 9.93 | 64 | 322847 | 2095 | 79419382 |
Dialysis | 71.59 | 9.93 | 200 | 322711 | 18262 | 79403215 |
Gastrointestinal disorder | 71.54 | 9.93 | 254 | 322657 | 121951 | 79299526 |
Chest pain | 70.63 | 9.93 | 1567 | 321344 | 280737 | 79140740 |
Cardiac failure acute | 70.42 | 9.93 | 202 | 322709 | 18727 | 79402750 |
Swollen joint count increased | 70.42 | 9.93 | 6 | 322905 | 22921 | 79398556 |
Flushing | 70.41 | 9.93 | 604 | 322307 | 87664 | 79333813 |
Cardiac operation | 70.40 | 9.93 | 94 | 322817 | 4918 | 79416559 |
Haematochezia | 70.05 | 9.93 | 600 | 322311 | 87045 | 79334432 |
Catheter site rash | 69.63 | 9.93 | 46 | 322865 | 959 | 79420518 |
Red blood cell sedimentation rate increased | 69.06 | 9.93 | 51 | 322860 | 45891 | 79375586 |
Conjunctival haemorrhage | 68.96 | 9.93 | 101 | 322810 | 5764 | 79415713 |
Cardioactive drug level increased | 68.84 | 9.93 | 80 | 322831 | 3629 | 79417848 |
Potentiating drug interaction | 68.59 | 9.93 | 126 | 322785 | 8693 | 79412784 |
Choroidal haemorrhage | 68.38 | 9.93 | 26 | 322885 | 149 | 79421328 |
Food interaction | 68.22 | 9.93 | 56 | 322855 | 1646 | 79419831 |
Hyperkalaemia | 68.12 | 9.93 | 736 | 322175 | 113662 | 79307815 |
Prothrombin time abnormal | 67.97 | 9.93 | 47 | 322864 | 1059 | 79420418 |
Abdominal discomfort | 67.82 | 9.93 | 668 | 322243 | 250059 | 79171418 |
Pulmonary arterial pressure increased | 66.40 | 9.93 | 87 | 322824 | 4468 | 79417009 |
Compartment syndrome | 66.36 | 9.93 | 92 | 322819 | 4990 | 79416487 |
Oxygen consumption increased | 66.31 | 9.93 | 91 | 322820 | 4888 | 79416589 |
Blood pressure fluctuation | 66.09 | 9.93 | 106 | 322805 | 67039 | 79354438 |
Wheezing | 65.97 | 9.93 | 246 | 322665 | 116418 | 79305059 |
Pulmonary endarterectomy | 65.53 | 9.93 | 27 | 322884 | 197 | 79421280 |
Gout | 65.52 | 9.93 | 235 | 322676 | 24514 | 79396963 |
Haematoma evacuation | 65.20 | 9.93 | 30 | 322881 | 294 | 79421183 |
Cardiac disorder | 65.11 | 9.93 | 473 | 322438 | 65284 | 79356193 |
Acute myeloid leukaemia | 64.85 | 9.93 | 22 | 322889 | 30863 | 79390614 |
Infusion site erythema | 64.74 | 9.93 | 128 | 322783 | 9332 | 79412145 |
Oxygen saturation decreased | 64.67 | 9.93 | 803 | 322108 | 128244 | 79293233 |
Colitis | 63.78 | 9.93 | 125 | 322786 | 73182 | 79348295 |
Acute kidney injury | 63.76 | 9.93 | 2640 | 320271 | 516764 | 78904713 |
Ventricular fibrillation | 63.40 | 9.93 | 277 | 322634 | 31649 | 79389828 |
Bursitis | 63.28 | 9.93 | 33 | 322878 | 35811 | 79385666 |
Loss of personal independence in daily activities | 62.89 | 9.93 | 209 | 322702 | 102371 | 79319106 |
White blood cell count decreased | 62.79 | 9.93 | 475 | 322436 | 187813 | 79233664 |
Injection site swelling | 62.62 | 9.93 | 59 | 322852 | 47073 | 79374404 |
Adrenal haemorrhage | 62.38 | 9.93 | 36 | 322875 | 584 | 79420893 |
International normalised ratio | 62.37 | 9.93 | 22 | 322889 | 98 | 79421379 |
Generalised tonic-clonic seizure | 61.90 | 9.93 | 52 | 322859 | 43858 | 79377619 |
Gastrointestinal arteriovenous malformation | 61.53 | 9.93 | 42 | 322869 | 926 | 79420551 |
Cardiac valve replacement complication | 61.38 | 9.93 | 26 | 322885 | 205 | 79421272 |
Catheterisation cardiac | 60.74 | 9.93 | 94 | 322817 | 5634 | 79415843 |
Device expulsion | 60.58 | 9.93 | 15 | 322896 | 25846 | 79395631 |
Gastritis erosive | 60.52 | 9.93 | 135 | 322776 | 10712 | 79410765 |
Medical device change | 60.40 | 9.93 | 33 | 322878 | 479 | 79420998 |
Foot deformity | 60.36 | 9.93 | 12 | 322899 | 24062 | 79397415 |
Seizure | 60.34 | 9.93 | 482 | 322429 | 188352 | 79233125 |
Serotonin syndrome | 60.25 | 9.93 | 56 | 322855 | 44971 | 79376506 |
Accidental exposure to product | 59.65 | 9.93 | 26 | 322885 | 31296 | 79390181 |
Dystonia | 59.60 | 9.93 | 8 | 322903 | 21391 | 79400086 |
Vascular pseudoaneurysm | 59.04 | 9.93 | 72 | 322839 | 3438 | 79418039 |
Cerebral haematoma | 58.68 | 9.93 | 111 | 322800 | 7831 | 79413646 |
Pulmonary oedema | 58.32 | 9.93 | 580 | 322331 | 87674 | 79333803 |
Insomnia | 58.30 | 9.93 | 673 | 322238 | 244497 | 79176980 |
Brain natriuretic peptide increased | 58.01 | 9.93 | 118 | 322793 | 8782 | 79412695 |
Illness | 57.47 | 9.93 | 62 | 322849 | 46449 | 79375028 |
Device related sepsis | 57.42 | 9.93 | 96 | 322815 | 6144 | 79415333 |
Neoplasm progression | 57.34 | 9.93 | 75 | 322836 | 51607 | 79369870 |
Liver injury | 57.02 | 9.93 | 88 | 322823 | 56526 | 79364951 |
Sedation | 56.87 | 9.93 | 76 | 322835 | 51819 | 79369658 |
Haemothorax | 56.84 | 9.93 | 89 | 322822 | 5389 | 79416088 |
Mobility decreased | 56.57 | 9.93 | 278 | 322633 | 121897 | 79299580 |
Pelvic haematoma | 56.54 | 9.93 | 38 | 322873 | 816 | 79420661 |
Cardioversion | 56.23 | 9.93 | 55 | 322856 | 2043 | 79419434 |
Mediastinal haematoma | 56.04 | 9.93 | 24 | 322887 | 195 | 79421282 |
Abdominal distension | 55.49 | 9.93 | 734 | 322177 | 118916 | 79302561 |
Rheumatoid nodule | 55.14 | 9.93 | 4 | 322907 | 17434 | 79404043 |
Atrial thrombosis | 55.12 | 9.93 | 71 | 322840 | 3585 | 79417892 |
Blood pressure increased | 55.12 | 9.93 | 568 | 322343 | 210792 | 79210685 |
Psychotic disorder | 54.80 | 9.93 | 52 | 322859 | 41350 | 79380127 |
Arthritis | 54.58 | 9.93 | 259 | 322652 | 114621 | 79306856 |
Hepatotoxicity | 54.47 | 9.93 | 77 | 322834 | 51275 | 79370202 |
Prescribed overdose | 54.47 | 9.93 | 44 | 322867 | 37839 | 79383638 |
Transplant evaluation | 54.13 | 9.93 | 49 | 322862 | 1648 | 79419829 |
Cytomegalovirus infection | 53.64 | 9.93 | 56 | 322855 | 42588 | 79378889 |
Brain herniation | 53.53 | 9.93 | 103 | 322808 | 7360 | 79414117 |
Gastric ulcer haemorrhage | 53.37 | 9.93 | 115 | 322796 | 8912 | 79412565 |
Scrotal haematoma | 53.16 | 9.93 | 18 | 322893 | 69 | 79421408 |
Hepatic cytolysis | 52.56 | 9.93 | 22 | 322889 | 27129 | 79394348 |
Mesenteric haematoma | 51.69 | 9.93 | 14 | 322897 | 18 | 79421459 |
Congestive hepatopathy | 51.59 | 9.93 | 77 | 322834 | 4470 | 79417007 |
Transient ischaemic attack | 51.57 | 9.93 | 378 | 322533 | 52317 | 79369160 |
Antiphospholipid syndrome | 51.48 | 9.93 | 50 | 322861 | 1841 | 79419636 |
Thrombocytopenia | 51.01 | 9.93 | 761 | 322150 | 264498 | 79156979 |
Pulmonary haemorrhage | 50.87 | 9.93 | 153 | 322758 | 14564 | 79406913 |
Spinal subdural haematoma | 50.84 | 9.93 | 23 | 322888 | 216 | 79421261 |
Ascites | 50.61 | 9.93 | 498 | 322413 | 75064 | 79346413 |
Cellulitis | 50.14 | 9.93 | 668 | 322243 | 108392 | 79313085 |
Duodenal ulcer | 49.97 | 9.93 | 163 | 322748 | 16206 | 79405271 |
Hyphaema | 49.95 | 9.93 | 36 | 322875 | 868 | 79420609 |
Protein C decreased | 49.84 | 9.93 | 17 | 322894 | 67 | 79421410 |
Venous pressure jugular increased | 49.38 | 9.93 | 42 | 322869 | 1298 | 79420179 |
Anticoagulation drug level decreased | 49.32 | 9.93 | 21 | 322890 | 168 | 79421309 |
Obesity | 49.02 | 9.93 | 42 | 322869 | 35083 | 79386394 |
Oral herpes | 48.88 | 9.93 | 25 | 322886 | 27429 | 79394048 |
Night sweats | 48.71 | 9.93 | 85 | 322826 | 52010 | 79369467 |
Angioedema | 48.64 | 9.93 | 152 | 322759 | 75883 | 79345594 |
Eye haemorrhage | 48.46 | 9.93 | 116 | 322795 | 9641 | 79411836 |
Therapeutic response decreased | 48.38 | 9.93 | 126 | 322785 | 66727 | 79354750 |
Pulmonary thrombosis | 48.33 | 9.93 | 133 | 322778 | 12038 | 79409439 |
Tongue haematoma | 48.32 | 9.93 | 22 | 322889 | 210 | 79421267 |
Mouth haemorrhage | 48.24 | 9.93 | 124 | 322787 | 10775 | 79410702 |
Therapy change | 48.11 | 9.93 | 98 | 322813 | 7301 | 79414176 |
Intentional self-injury | 47.43 | 9.93 | 37 | 322874 | 32382 | 79389095 |
Diverticulum intestinal haemorrhagic | 47.06 | 9.93 | 69 | 322842 | 3942 | 79417535 |
Spinal cord haematoma | 47.00 | 9.93 | 24 | 322887 | 301 | 79421176 |
Arteriovenous malformation | 46.89 | 9.93 | 46 | 322865 | 1715 | 79419762 |
Nasal congestion | 46.72 | 9.93 | 495 | 322416 | 76057 | 79345420 |
Wrong technique in product usage process | 46.33 | 9.93 | 149 | 322762 | 73726 | 79347751 |
Intracardiac thrombus | 46.30 | 9.93 | 71 | 322840 | 4222 | 79417255 |
Gangrene | 46.07 | 9.93 | 108 | 322803 | 8856 | 79412621 |
Lymphopenia | 45.83 | 9.93 | 34 | 322877 | 30523 | 79390954 |
Agitation | 45.52 | 9.93 | 228 | 322683 | 99487 | 79321990 |
Lymphocyte count decreased | 45.28 | 9.93 | 76 | 322835 | 47213 | 79374264 |
Catheter removal | 45.18 | 9.93 | 30 | 322881 | 631 | 79420846 |
Coagulation time shortened | 44.35 | 9.93 | 25 | 322886 | 387 | 79421090 |
Drug ineffective for unapproved indication | 44.02 | 9.93 | 88 | 322823 | 51150 | 79370327 |
Muscle spasticity | 43.88 | 9.93 | 16 | 322895 | 21459 | 79400018 |
Hip arthroplasty | 43.81 | 9.93 | 48 | 322863 | 35708 | 79385769 |
Sedation complication | 43.30 | 9.93 | 6 | 322905 | 15663 | 79405814 |
Bronchopulmonary aspergillosis | 43.26 | 9.93 | 18 | 322893 | 22276 | 79399201 |
Aphthous ulcer | 43.23 | 9.93 | 8 | 322903 | 16881 | 79404596 |
Embolic stroke | 43.21 | 9.93 | 97 | 322814 | 7729 | 79413748 |
Immunodeficiency | 43.18 | 9.93 | 17 | 322894 | 21751 | 79399726 |
Medical device site thrombosis | 42.66 | 9.93 | 13 | 322898 | 32 | 79421445 |
Heart valve replacement | 42.58 | 9.93 | 33 | 322878 | 891 | 79420586 |
Vitamin K deficiency | 42.55 | 9.93 | 30 | 322881 | 698 | 79420779 |
Renal haemorrhage | 42.44 | 9.93 | 49 | 322862 | 2207 | 79419270 |
Mallory-Weiss syndrome | 42.39 | 9.93 | 55 | 322856 | 2797 | 79418680 |
Chest wall haematoma | 42.35 | 9.93 | 25 | 322886 | 424 | 79421053 |
Prosthetic cardiac valve thrombosis | 42.33 | 9.93 | 14 | 322897 | 49 | 79421428 |
Traumatic intracranial haemorrhage | 42.00 | 9.93 | 37 | 322874 | 1200 | 79420277 |
Appendicitis | 41.73 | 9.93 | 181 | 322730 | 20613 | 79400864 |
Basal cell carcinoma | 41.71 | 9.93 | 54 | 322857 | 37321 | 79384156 |
Hepatocellular injury | 41.53 | 9.93 | 81 | 322830 | 47512 | 79373965 |
Hypercholesterolaemia | 41.16 | 9.93 | 21 | 322890 | 23074 | 79398403 |
Febrile bone marrow aplasia | 41.13 | 9.93 | 3 | 322908 | 13017 | 79408460 |
Rash maculo-papular | 41.11 | 9.93 | 105 | 322806 | 55973 | 79365504 |
Knee arthroplasty | 40.95 | 9.93 | 70 | 322841 | 43178 | 79378299 |
Duodenal ulcer haemorrhage | 40.92 | 9.93 | 90 | 322821 | 7073 | 79414404 |
Aggression | 40.87 | 9.93 | 91 | 322820 | 50867 | 79370610 |
Blue toe syndrome | 40.82 | 9.93 | 27 | 322884 | 564 | 79420913 |
Aplastic anaemia | 40.77 | 9.93 | 11 | 322900 | 17894 | 79403583 |
Foetal warfarin syndrome | 40.62 | 9.93 | 9 | 322902 | 0 | 79421477 |
Dry eye | 40.55 | 9.93 | 54 | 322857 | 36877 | 79384600 |
Pneumocystis jirovecii pneumonia | 40.54 | 9.93 | 43 | 322868 | 32465 | 79389012 |
Swelling | 40.53 | 9.93 | 625 | 322286 | 216086 | 79205391 |
Disturbance in attention | 40.51 | 9.93 | 91 | 322820 | 50710 | 79370767 |
Diabetic ketoacidosis | 40.50 | 9.93 | 47 | 322864 | 34075 | 79387402 |
Intentional product misuse | 40.42 | 9.93 | 223 | 322688 | 94942 | 79326535 |
Penile necrosis | 40.33 | 9.93 | 13 | 322898 | 41 | 79421436 |
Herpes zoster | 40.15 | 9.93 | 217 | 322694 | 92866 | 79328611 |
Haemorrhagic diathesis | 40.05 | 9.93 | 81 | 322830 | 6003 | 79415474 |
Therapeutic product effect increased | 39.91 | 9.93 | 40 | 322871 | 1531 | 79419946 |
Dizziness postural | 39.86 | 9.93 | 120 | 322791 | 11429 | 79410048 |
Hypoprothrombinaemia | 39.75 | 9.93 | 29 | 322882 | 713 | 79420764 |
Neuropathy peripheral | 39.22 | 9.93 | 374 | 322537 | 140931 | 79280546 |
Device connection issue | 38.93 | 9.93 | 33 | 322878 | 1015 | 79420462 |
Hepatitis | 38.84 | 9.93 | 107 | 322804 | 55620 | 79365857 |
Anticoagulation drug level increased | 38.76 | 9.93 | 29 | 322882 | 742 | 79420735 |
Haemophagocytic lymphohistiocytosis | 38.70 | 9.93 | 20 | 322891 | 21817 | 79399660 |
Cognitive disorder | 38.52 | 9.93 | 149 | 322762 | 69777 | 79351700 |
Concomitant disease progression | 38.25 | 9.93 | 58 | 322853 | 3415 | 79418062 |
Diverticulum | 38.21 | 9.93 | 140 | 322771 | 14756 | 79406721 |
Blood phosphorus increased | 38.08 | 9.93 | 110 | 322801 | 10237 | 79411240 |
Conjunctivitis | 38.07 | 9.93 | 29 | 322882 | 25686 | 79395791 |
Product administration error | 38.06 | 9.93 | 240 | 322671 | 31606 | 79389871 |
Lip dry | 38 | 9.93 | 8 | 322903 | 15410 | 79406067 |
Vascular pseudoaneurysm ruptured | 37.92 | 9.93 | 17 | 322894 | 156 | 79421321 |
Drug monitoring procedure not performed | 37.90 | 9.93 | 32 | 322879 | 979 | 79420498 |
Joint stiffness | 37.83 | 9.93 | 67 | 322844 | 40763 | 79380714 |
Cerebral infarction | 37.71 | 9.93 | 315 | 322596 | 45361 | 79376116 |
Hypophagia | 37.52 | 9.93 | 313 | 322598 | 45054 | 79376423 |
Thalamus haemorrhage | 37.45 | 9.93 | 41 | 322870 | 1741 | 79419736 |
Anticoagulation drug level abnormal | 37.33 | 9.93 | 11 | 322900 | 23 | 79421454 |
Injury | 37.23 | 9.93 | 174 | 322737 | 77322 | 79344155 |
Osteoporosis | 36.89 | 9.93 | 105 | 322806 | 54007 | 79367470 |
Bone marrow failure | 36.47 | 9.93 | 97 | 322814 | 51010 | 79370467 |
Aortic valve replacement | 36.23 | 9.93 | 35 | 322876 | 1280 | 79420197 |
Tracheal calcification | 36.11 | 9.93 | 8 | 322903 | 0 | 79421477 |
Hydrocephalus | 36.08 | 9.93 | 98 | 322813 | 8802 | 79412675 |
Neuroleptic malignant syndrome | 36.02 | 9.93 | 35 | 322876 | 27524 | 79393953 |
Catheter site discolouration | 36.00 | 9.93 | 15 | 322896 | 113 | 79421364 |
Catheter site irritation | 35.97 | 9.93 | 25 | 322886 | 568 | 79420909 |
Gastric ulcer | 35.96 | 9.93 | 248 | 322663 | 33657 | 79387820 |
Cardiac ablation | 35.94 | 9.93 | 45 | 322866 | 2208 | 79419269 |
Exercise tolerance decreased | 35.90 | 9.93 | 99 | 322812 | 8972 | 79412505 |
Palmar-plantar erythrodysaesthesia syndrome | 35.82 | 9.93 | 49 | 322862 | 33085 | 79388392 |
Lymphadenopathy | 35.81 | 9.93 | 104 | 322807 | 53143 | 79368334 |
Condition aggravated | 35.64 | 9.93 | 1662 | 321249 | 499462 | 78922015 |
Sinus tachycardia | 35.63 | 9.93 | 59 | 322852 | 36849 | 79384628 |
Mental status changes | 35.41 | 9.93 | 421 | 322490 | 66538 | 79354939 |
Pregnancy | 35.21 | 9.93 | 34 | 322877 | 26817 | 79394660 |
Orthopnoea | 35.08 | 9.93 | 105 | 322806 | 9968 | 79411509 |
Drug resistance | 35.00 | 9.93 | 74 | 322837 | 42139 | 79379338 |
Steroid dependence | 34.92 | 9.93 | 48 | 322863 | 2582 | 79418895 |
Rales | 34.85 | 9.93 | 167 | 322744 | 19834 | 79401643 |
Subarachnoid haematoma | 34.76 | 9.93 | 19 | 322892 | 276 | 79421201 |
Pancreatitis acute | 34.75 | 9.93 | 95 | 322816 | 49509 | 79371968 |
Dermatitis contact | 34.70 | 9.93 | 111 | 322800 | 10922 | 79410555 |
Facet joint syndrome | 34.59 | 9.93 | 3 | 322908 | 11299 | 79410178 |
Catheter site related reaction | 34.57 | 9.93 | 33 | 322878 | 1189 | 79420288 |
Atrial tachycardia | 34.56 | 9.93 | 84 | 322827 | 7049 | 79414428 |
Bradyarrhythmia | 34.49 | 9.93 | 61 | 322850 | 4085 | 79417392 |
Schizophrenia | 34.20 | 9.93 | 10 | 322901 | 15430 | 79406047 |
Prothrombin consumption time prolonged | 34.05 | 9.93 | 11 | 322900 | 35 | 79421442 |
Sleep disorder due to a general medical condition | 33.99 | 9.93 | 8 | 322903 | 14269 | 79407208 |
Emergency care | 33.99 | 9.93 | 31 | 322880 | 1053 | 79420424 |
Lethargy | 33.75 | 9.93 | 489 | 322422 | 80803 | 79340674 |
Obstructive airways disorder | 33.54 | 9.93 | 47 | 322864 | 31412 | 79390065 |
Acute generalised exanthematous pustulosis | 33.37 | 9.93 | 14 | 322897 | 17240 | 79404237 |
Joint range of motion decreased | 33.26 | 9.93 | 52 | 322859 | 33230 | 79388247 |
Grip strength decreased | 33.23 | 9.93 | 24 | 322887 | 21845 | 79399632 |
Infective pulmonary exacerbation of cystic fibrosis | 33.08 | 9.93 | 6 | 322905 | 12845 | 79408632 |
Fatigue | 33.01 | 9.93 | 3280 | 319631 | 926447 | 78495030 |
Ankylosing spondylitis | 32.97 | 9.93 | 5 | 322906 | 12200 | 79409277 |
Aortic stenosis | 32.89 | 9.93 | 85 | 322826 | 7410 | 79414067 |
Blood urea increased | 32.88 | 9.93 | 322 | 322589 | 48468 | 79373009 |
Device interaction | 32.87 | 9.93 | 26 | 322885 | 724 | 79420753 |
Endarterectomy | 32.69 | 9.93 | 20 | 322891 | 363 | 79421114 |
Drug-induced liver injury | 32.62 | 9.93 | 147 | 322764 | 65970 | 79355507 |
Restlessness | 32.60 | 9.93 | 89 | 322822 | 46403 | 79375074 |
Large intestinal haemorrhage | 32.54 | 9.93 | 48 | 322863 | 2757 | 79418720 |
Mineral supplementation | 32.34 | 9.93 | 27 | 322884 | 813 | 79420664 |
Muscle spasms | 32.30 | 9.93 | 505 | 322406 | 174225 | 79247252 |
Exostosis | 32.09 | 9.93 | 14 | 322897 | 16844 | 79404633 |
Mouth ulceration | 32.08 | 9.93 | 67 | 322844 | 38327 | 79383150 |
Arrhythmia | 31.86 | 9.93 | 384 | 322527 | 60888 | 79360589 |
Anovulatory cycle | 31.85 | 9.93 | 14 | 322897 | 122 | 79421355 |
Prescribed underdose | 31.56 | 9.93 | 44 | 322867 | 29470 | 79392007 |
Sinus node dysfunction | 31.42 | 9.93 | 85 | 322826 | 7616 | 79413861 |
Posterior reversible encephalopathy syndrome | 31.41 | 9.93 | 36 | 322875 | 26245 | 79395232 |
Neurotoxicity | 31.37 | 9.93 | 52 | 322859 | 32466 | 79389011 |
Autoimmune disorder | 31.30 | 9.93 | 14 | 322897 | 16598 | 79404879 |
Inappropriate schedule of product administration | 31.28 | 9.93 | 368 | 322543 | 133260 | 79288217 |
Mitral valve replacement | 31.26 | 9.93 | 20 | 322891 | 394 | 79421083 |
Myxoedema coma | 31.12 | 9.93 | 25 | 322886 | 712 | 79420765 |
Hyperhidrosis | 31.07 | 9.93 | 429 | 322482 | 151063 | 79270414 |
Graft versus host disease | 31.03 | 9.93 | 11 | 322900 | 15015 | 79406462 |
Laryngeal haematoma | 31.02 | 9.93 | 15 | 322896 | 166 | 79421311 |
Acute respiratory failure | 30.89 | 9.93 | 373 | 322538 | 59168 | 79362309 |
Infected skin ulcer | 30.86 | 9.93 | 52 | 322859 | 3349 | 79418128 |
Poisoning deliberate | 30.85 | 9.93 | 19 | 322892 | 18809 | 79402668 |
Therapy partial responder | 30.74 | 9.93 | 16 | 322895 | 17381 | 79404096 |
Cholestasis | 30.69 | 9.93 | 108 | 322803 | 52001 | 79369476 |
Immune reconstitution inflammatory syndrome | 30.59 | 9.93 | 9 | 322902 | 13832 | 79407645 |
Blood creatinine increased | 30.42 | 9.93 | 833 | 322078 | 154224 | 79267253 |
Ear pain | 30.39 | 9.93 | 54 | 322857 | 32815 | 79388662 |
Sciatica | 30.34 | 9.93 | 55 | 322856 | 33167 | 79388310 |
Tendonitis | 30.30 | 9.93 | 31 | 322880 | 23799 | 79397678 |
Device infusion issue | 30.21 | 9.93 | 42 | 322869 | 2284 | 79419193 |
Breast haematoma | 30.03 | 9.93 | 15 | 322896 | 179 | 79421298 |
Infusion site haemorrhage | 30.01 | 9.93 | 54 | 322857 | 3666 | 79417811 |
Deep vein thrombosis postoperative | 29.99 | 9.93 | 4 | 322907 | 10748 | 79410729 |
Torsade de pointes | 29.94 | 9.93 | 156 | 322755 | 19156 | 79402321 |
Catheter culture positive | 29.85 | 9.93 | 16 | 322895 | 223 | 79421254 |
Haemorrhoidal haemorrhage | 29.76 | 9.93 | 77 | 322834 | 6718 | 79414759 |
Protein S deficiency | 29.67 | 9.93 | 14 | 322897 | 146 | 79421331 |
Colonic haematoma | 29.67 | 9.93 | 12 | 322899 | 83 | 79421394 |
Drug tolerance decreased | 29.50 | 9.93 | 8 | 322903 | 12970 | 79408507 |
Atheroembolism | 29.45 | 9.93 | 18 | 322893 | 326 | 79421151 |
Atrial septal defect repair | 29.34 | 9.93 | 20 | 322891 | 440 | 79421037 |
Emotional distress | 29.17 | 9.93 | 75 | 322836 | 39894 | 79381583 |
Aspergillus infection | 29.15 | 9.93 | 21 | 322890 | 19140 | 79402337 |
Hypokalaemia | 29.15 | 9.93 | 409 | 322502 | 143631 | 79277846 |
Petechiae | 29.09 | 9.93 | 162 | 322749 | 20403 | 79401074 |
Walking distance test abnormal | 28.99 | 9.93 | 24 | 322887 | 714 | 79420763 |
Periorbital haematoma | 28.88 | 9.93 | 27 | 322884 | 947 | 79420530 |
Heart rate increased | 28.85 | 9.93 | 666 | 322245 | 120058 | 79301419 |
Systemic infection | 28.76 | 9.93 | 3 | 322908 | 9749 | 79411728 |
Pneumonitis | 28.44 | 9.93 | 138 | 322773 | 60722 | 79360755 |
Disability | 28.43 | 9.93 | 17 | 322894 | 17103 | 79404374 |
Purpura | 28.41 | 9.93 | 155 | 322756 | 19372 | 79402105 |
Ovarian haemorrhage | 28.25 | 9.93 | 17 | 322894 | 299 | 79421178 |
Gravitational oedema | 28.18 | 9.93 | 36 | 322875 | 1803 | 79419674 |
Osteopenia | 28.10 | 9.93 | 20 | 322891 | 18344 | 79403133 |
Infusion site warmth | 28.04 | 9.93 | 32 | 322879 | 1423 | 79420054 |
Drug eruption | 27.97 | 9.93 | 88 | 322823 | 43847 | 79377630 |
Nephropathy | 27.97 | 9.93 | 95 | 322816 | 9643 | 79411834 |
Vascular calcification | 27.93 | 9.93 | 28 | 322883 | 1072 | 79420405 |
Pancreatitis | 27.87 | 9.93 | 163 | 322748 | 68412 | 79353065 |
Central venous catheter removal | 27.87 | 9.93 | 20 | 322891 | 479 | 79420998 |
Cerebellar haematoma | 27.77 | 9.93 | 22 | 322889 | 614 | 79420863 |
Loss of consciousness | 27.72 | 9.93 | 883 | 322028 | 167060 | 79254417 |
Dizziness exertional | 27.55 | 9.93 | 21 | 322890 | 553 | 79420924 |
Breast necrosis | 27.45 | 9.93 | 11 | 322900 | 74 | 79421403 |
Subdural haematoma evacuation | 27.45 | 9.93 | 11 | 322900 | 74 | 79421403 |
Gastric antral vascular ectasia | 27.34 | 9.93 | 26 | 322885 | 932 | 79420545 |
Sciatic nerve palsy | 27.33 | 9.93 | 11 | 322900 | 75 | 79421402 |
Pericardial effusion | 27.28 | 9.93 | 297 | 322614 | 45940 | 79375537 |
Chest tube insertion | 27.27 | 9.93 | 13 | 322898 | 139 | 79421338 |
Extrapyramidal disorder | 27.17 | 9.93 | 31 | 322880 | 22648 | 79398829 |
Catheter site vesicles | 27.15 | 9.93 | 17 | 322894 | 322 | 79421155 |
Cytomegalovirus viraemia | 27.15 | 9.93 | 9 | 322902 | 12812 | 79408665 |
Oxygen therapy | 27.12 | 9.93 | 44 | 322867 | 2746 | 79418731 |
Blood urine present | 27.02 | 9.93 | 163 | 322748 | 21134 | 79400343 |
Vascular device infection | 26.71 | 9.93 | 97 | 322814 | 10179 | 79411298 |
Anaphylactic shock | 26.69 | 9.93 | 67 | 322844 | 35929 | 79385548 |
Diffuse large B-cell lymphoma | 26.67 | 9.93 | 8 | 322903 | 12141 | 79409336 |
Hypercalcaemia | 26.62 | 9.93 | 74 | 322837 | 38356 | 79383121 |
Adjustment disorder with depressed mood | 26.27 | 9.93 | 3 | 322908 | 9083 | 79412394 |
Depressed mood | 26.25 | 9.93 | 104 | 322807 | 48376 | 79373101 |
Hallucination, auditory | 26.22 | 9.93 | 27 | 322884 | 20666 | 79400811 |
Infusion site cellulitis | 26.22 | 9.93 | 16 | 322895 | 289 | 79421188 |
Prostate cancer | 26.19 | 9.93 | 60 | 322851 | 33208 | 79388269 |
Breast cancer female | 26.17 | 9.93 | 7 | 322904 | 11454 | 79410023 |
Tremor | 26.16 | 9.93 | 508 | 322403 | 169575 | 79251902 |
Crying | 26.01 | 9.93 | 33 | 322878 | 23010 | 79398467 |
Drug reaction with eosinophilia and systemic symptoms | 25.95 | 9.93 | 153 | 322758 | 64091 | 79357386 |
Dilatation ventricular | 25.90 | 9.93 | 54 | 322857 | 4090 | 79417387 |
Thrombectomy | 25.88 | 9.93 | 16 | 322895 | 296 | 79421181 |
Implant site haematoma | 25.82 | 9.93 | 13 | 322898 | 158 | 79421319 |
Cardiac pacemaker replacement | 25.81 | 9.93 | 19 | 322892 | 474 | 79421003 |
Irritability | 25.78 | 9.93 | 83 | 322828 | 41061 | 79380416 |
Respiratory failure | 25.76 | 9.93 | 935 | 321976 | 179976 | 79241501 |
Product storage error | 25.73 | 9.93 | 17 | 322894 | 16209 | 79405268 |
Procedural haemorrhage | 25.62 | 9.93 | 58 | 322853 | 4648 | 79416829 |
Disease recurrence | 25.59 | 9.93 | 92 | 322819 | 44017 | 79377460 |
Neutropenic sepsis | 25.45 | 9.93 | 44 | 322867 | 27020 | 79394457 |
Catheter site warmth | 25.43 | 9.93 | 15 | 322896 | 254 | 79421223 |
Spinal cord haemorrhage | 25.37 | 9.93 | 20 | 322891 | 554 | 79420923 |
Tumour lysis syndrome | 25.28 | 9.93 | 36 | 322875 | 23903 | 79397574 |
Embolism | 25.28 | 9.93 | 118 | 322793 | 13864 | 79407613 |
Nasopharyngitis | 25.27 | 9.93 | 809 | 322102 | 253072 | 79168405 |
BK virus infection | 25.23 | 9.93 | 3 | 322908 | 8801 | 79412676 |
Heart rate irregular | 25.20 | 9.93 | 222 | 322689 | 32457 | 79389020 |
Hypertriglyceridaemia | 25.18 | 9.93 | 10 | 322901 | 12730 | 79408747 |
Hepatic steatosis | 25.16 | 9.93 | 74 | 322837 | 37664 | 79383813 |
Cor pulmonale | 25.15 | 9.93 | 38 | 322873 | 2230 | 79419247 |
Cardiac valve disease | 25.08 | 9.93 | 65 | 322846 | 5676 | 79415801 |
Renal vascular thrombosis | 24.99 | 9.93 | 10 | 322901 | 67 | 79421410 |
Renal haematoma | 24.96 | 9.93 | 23 | 322888 | 792 | 79420685 |
Calcium deficiency | 24.90 | 9.93 | 24 | 322887 | 875 | 79420602 |
Acne | 24.85 | 9.93 | 45 | 322866 | 27145 | 79394332 |
Neutrophil count increased | 24.81 | 9.93 | 51 | 322860 | 29345 | 79392132 |
Blood potassium increased | 24.75 | 9.93 | 203 | 322708 | 29072 | 79392405 |
Hypovolaemic shock | 24.74 | 9.93 | 107 | 322804 | 12169 | 79409308 |
Pharyngeal haematoma | 24.72 | 9.93 | 12 | 322899 | 134 | 79421343 |
Device breakage | 24.63 | 9.93 | 97 | 322814 | 10578 | 79410899 |
Small intestinal haemorrhage | 24.57 | 9.93 | 53 | 322858 | 4110 | 79417367 |
Cataract | 24.53 | 9.93 | 149 | 322762 | 61971 | 79359506 |
Injection site rash | 24.41 | 9.93 | 22 | 322889 | 17932 | 79403545 |
COVID-19 pneumonia | 24.40 | 9.93 | 50 | 322861 | 28799 | 79392678 |
Epstein-Barr virus infection | 24.39 | 9.93 | 14 | 322897 | 14402 | 79407075 |
Musculoskeletal pain | 24.29 | 9.93 | 281 | 322630 | 102073 | 79319404 |
Injection site warmth | 24.18 | 9.93 | 15 | 322896 | 14792 | 79406685 |
Blood viscosity decreased | 24.15 | 9.93 | 10 | 322901 | 74 | 79421403 |
Unevaluable event | 24.12 | 9.93 | 337 | 322574 | 55248 | 79366229 |
Tuberculosis | 23.99 | 9.93 | 16 | 322895 | 15182 | 79406295 |
Panniculitis | 23.98 | 9.93 | 10 | 322901 | 12361 | 79409116 |
Ventricular hyperkinesia | 23.96 | 9.93 | 15 | 322896 | 284 | 79421193 |
Arteriovenous fistula site haemorrhage | 23.91 | 9.93 | 16 | 322895 | 341 | 79421136 |
Adenovirus infection | 23.91 | 9.93 | 3 | 322908 | 8444 | 79413033 |
Protein S decreased | 23.89 | 9.93 | 11 | 322900 | 108 | 79421369 |
Abnormal behaviour | 23.86 | 9.93 | 72 | 322839 | 36349 | 79385128 |
Epilepsy | 23.85 | 9.93 | 85 | 322826 | 40775 | 79380702 |
Hyperbilirubinaemia | 23.85 | 9.93 | 39 | 322872 | 24479 | 79396998 |
Femoral nerve palsy | 23.81 | 9.93 | 10 | 322901 | 77 | 79421400 |
Left ventricular failure | 23.70 | 9.93 | 89 | 322822 | 9492 | 79411985 |
Glomerular filtration rate | 23.68 | 9.93 | 12 | 322899 | 148 | 79421329 |
Migraine | 23.67 | 9.93 | 233 | 322678 | 87260 | 79334217 |
Uveitis | 23.63 | 9.93 | 20 | 322891 | 16810 | 79404667 |
Blood pressure systolic abnormal | 23.61 | 9.93 | 21 | 322890 | 17226 | 79404251 |
Dry mouth | 23.56 | 9.93 | 235 | 322676 | 87784 | 79333693 |
Ischaemic stroke | 23.48 | 9.93 | 221 | 322690 | 32910 | 79388567 |
Encephalopathy | 23.42 | 9.93 | 168 | 322743 | 67229 | 79354248 |
Apallic syndrome | 23.41 | 9.93 | 24 | 322887 | 944 | 79420533 |
Therapeutic response shortened | 23.34 | 9.93 | 18 | 322893 | 15845 | 79405632 |
Chills | 23.32 | 9.93 | 483 | 322428 | 159751 | 79261726 |
Hypoxia | 23.27 | 9.93 | 565 | 322346 | 102678 | 79318799 |
Withdrawal syndrome | 23.17 | 9.93 | 46 | 322865 | 26808 | 79394669 |
Carpal tunnel syndrome | 23.07 | 9.93 | 27 | 322884 | 19501 | 79401976 |
Substance abuse | 22.98 | 9.93 | 7 | 322904 | 10519 | 79410958 |
Multiple-drug resistance | 22.92 | 9.93 | 4 | 322907 | 8804 | 79412673 |
Incision site haemorrhage | 22.84 | 9.93 | 25 | 322886 | 1061 | 79420416 |
Blood culture negative | 22.79 | 9.93 | 13 | 322898 | 206 | 79421271 |
Heart valve operation | 22.79 | 9.93 | 13 | 322898 | 206 | 79421271 |
Metastases to bone | 22.70 | 9.93 | 40 | 322871 | 24387 | 79397090 |
Blood pressure systolic decreased | 22.68 | 9.93 | 97 | 322814 | 10979 | 79410498 |
Thrombotic microangiopathy | 22.65 | 9.93 | 29 | 322882 | 20140 | 79401337 |
Haemorrhagic arteriovenous malformation | 22.65 | 9.93 | 19 | 322892 | 576 | 79420901 |
Device difficult to use | 22.64 | 9.93 | 13 | 322898 | 13372 | 79408105 |
Rash erythematous | 22.59 | 9.93 | 139 | 322772 | 57630 | 79363847 |
Tongue haemorrhage | 22.58 | 9.93 | 24 | 322887 | 985 | 79420492 |
Pneumonia aspiration | 22.56 | 9.93 | 389 | 322522 | 66578 | 79354899 |
Hypertransaminasaemia | 22.54 | 9.93 | 10 | 322901 | 11914 | 79409563 |
Iris haemorrhage | 22.47 | 9.93 | 6 | 322905 | 7 | 79421470 |
Influenza like illness | 22.44 | 9.93 | 184 | 322727 | 71523 | 79349954 |
Haemorrhagic cholecystitis | 22.19 | 9.93 | 10 | 322901 | 93 | 79421384 |
Infusion site irritation | 22.10 | 9.93 | 21 | 322890 | 752 | 79420725 |
Haemorrhagic infarction | 22.08 | 9.93 | 21 | 322890 | 753 | 79420724 |
Live birth | 22.05 | 9.93 | 26 | 322885 | 18718 | 79402759 |
Renal failure | 22.01 | 9.93 | 1010 | 321901 | 199958 | 79221519 |
Urinary bladder haemorrhage | 21.99 | 9.93 | 38 | 322873 | 2498 | 79418979 |
Pneumonia | 21.97 | 9.93 | 3022 | 319889 | 657224 | 78764253 |
Adverse event | 21.95 | 9.93 | 148 | 322763 | 60066 | 79361411 |
Mood swings | 21.90 | 9.93 | 29 | 322882 | 19851 | 79401626 |
Skin weeping | 21.85 | 9.93 | 24 | 322887 | 1023 | 79420454 |
Platelet distribution width increased | 21.82 | 9.93 | 11 | 322900 | 134 | 79421343 |
Abortion spontaneous | 21.82 | 9.93 | 55 | 322856 | 29452 | 79392025 |
Angioplasty | 21.79 | 9.93 | 32 | 322879 | 1831 | 79419646 |
Transplant rejection | 21.77 | 9.93 | 28 | 322883 | 19409 | 79402068 |
Haemorrhagic ascites | 21.74 | 9.93 | 14 | 322897 | 279 | 79421198 |
Myocarditis | 21.67 | 9.93 | 34 | 322877 | 21699 | 79399778 |
Paracentesis | 21.67 | 9.93 | 27 | 322884 | 1318 | 79420159 |
Catheter site dermatitis | 21.56 | 9.93 | 10 | 322901 | 100 | 79421377 |
Cardiac flutter | 21.55 | 9.93 | 56 | 322855 | 4898 | 79416579 |
Intraocular haematoma | 21.50 | 9.93 | 7 | 322904 | 23 | 79421454 |
Pleural effusion | 21.48 | 9.93 | 754 | 322157 | 144508 | 79276969 |
Tumour haemorrhage | 21.37 | 9.93 | 50 | 322861 | 4094 | 79417383 |
Psychomotor hyperactivity | 21.33 | 9.93 | 22 | 322889 | 16827 | 79404650 |
Jugular vein distension | 21.31 | 9.93 | 28 | 322883 | 1442 | 79420035 |
Arteriovenous graft site haemorrhage | 21.24 | 9.93 | 6 | 322905 | 10 | 79421467 |
Feeling hot | 21.19 | 9.93 | 148 | 322763 | 59586 | 79361891 |
Haemorrhagic cerebral infarction | 21.17 | 9.93 | 28 | 322883 | 1451 | 79420026 |
Blood pressure diastolic abnormal | 21.16 | 9.93 | 28 | 322883 | 19174 | 79402303 |
Infusion site oedema | 21.14 | 9.93 | 22 | 322889 | 881 | 79420596 |
Liver function test increased | 21.11 | 9.93 | 86 | 322825 | 39687 | 79381790 |
Drug withdrawal syndrome | 21.09 | 9.93 | 71 | 322840 | 34647 | 79386830 |
Endocarditis | 21.08 | 9.93 | 92 | 322819 | 10505 | 79410972 |
Transaminases increased | 21.02 | 9.93 | 123 | 322788 | 51620 | 79369857 |
Extrasystoles | 20.98 | 9.93 | 72 | 322839 | 7347 | 79414130 |
Urinary bladder rupture | 20.89 | 9.93 | 10 | 322901 | 108 | 79421369 |
Pericarditis uraemic | 20.88 | 9.93 | 6 | 322905 | 11 | 79421466 |
Ubiquinone decreased | 20.84 | 9.93 | 7 | 322904 | 26 | 79421451 |
Oral mucosa haematoma | 20.73 | 9.93 | 8 | 322903 | 48 | 79421429 |
Hip fracture | 20.72 | 9.93 | 203 | 322708 | 30558 | 79390919 |
Coeliac disease | 20.71 | 9.93 | 10 | 322901 | 11341 | 79410136 |
Aspiration pleural cavity | 20.71 | 9.93 | 29 | 322882 | 1588 | 79419889 |
Catarrh | 20.70 | 9.93 | 34 | 322877 | 2144 | 79419333 |
Status epilepticus | 20.67 | 9.93 | 44 | 322867 | 24997 | 79396480 |
Factor V inhibition | 20.66 | 9.93 | 15 | 322896 | 366 | 79421111 |
Throat tightness | 20.65 | 9.93 | 52 | 322859 | 27855 | 79393622 |
Fat embolism | 20.65 | 9.93 | 16 | 322895 | 432 | 79421045 |
Hepatic failure | 20.59 | 9.93 | 154 | 322757 | 61058 | 79360419 |
Oral candidiasis | 20.56 | 9.93 | 57 | 322854 | 29571 | 79391906 |
Prothrombin level increased | 20.49 | 9.93 | 16 | 322895 | 437 | 79421040 |
Blood blister | 20.48 | 9.93 | 41 | 322870 | 3016 | 79418461 |
Ovarian rupture | 20.44 | 9.93 | 7 | 322904 | 28 | 79421449 |
Haemobilia | 20.39 | 9.93 | 17 | 322894 | 511 | 79420966 |
Heart sounds abnormal | 20.32 | 9.93 | 27 | 322884 | 1406 | 79420071 |
Hepatic haematoma | 20.20 | 9.93 | 21 | 322890 | 840 | 79420637 |
Pathogen resistance | 20.19 | 9.93 | 17 | 322894 | 14325 | 79407152 |
Right atrial enlargement | 20.18 | 9.93 | 15 | 322896 | 380 | 79421097 |
Dyskinesia | 20.07 | 9.93 | 103 | 322808 | 44670 | 79376807 |
Hypogammaglobulinaemia | 19.96 | 9.93 | 14 | 322897 | 12937 | 79408540 |
Lacrimal haemorrhage | 19.88 | 9.93 | 7 | 322904 | 31 | 79421446 |
Nasal polyps | 19.80 | 9.93 | 3 | 322908 | 7324 | 79414153 |
Pulmonary haematoma | 19.75 | 9.93 | 10 | 322901 | 123 | 79421354 |
Burns second degree | 19.75 | 9.93 | 37 | 322874 | 2591 | 79418886 |
Dermatitis atopic | 19.70 | 9.93 | 8 | 322903 | 10048 | 79411429 |
Accidental overdose | 19.68 | 9.93 | 246 | 322665 | 39335 | 79382142 |
Right ventricular dysfunction | 19.68 | 9.93 | 37 | 322874 | 2598 | 79418879 |
Heart transplant | 19.62 | 9.93 | 27 | 322884 | 1454 | 79420023 |
Injection site urticaria | 19.59 | 9.93 | 14 | 322897 | 12812 | 79408665 |
Poisoning | 19.56 | 9.93 | 46 | 322865 | 25226 | 79396251 |
Livedo reticularis | 19.54 | 9.93 | 48 | 322863 | 4055 | 79417422 |
Procedural pain | 19.53 | 9.93 | 40 | 322871 | 23044 | 79398433 |
Ulcer haemorrhage | 19.53 | 9.93 | 60 | 322851 | 5778 | 79415699 |
Protein C deficiency | 19.53 | 9.93 | 7 | 322904 | 33 | 79421444 |
Candida infection | 19.43 | 9.93 | 84 | 322827 | 38130 | 79383347 |
Transplant dysfunction | 19.41 | 9.93 | 3 | 322908 | 7218 | 79414259 |
Multiple sclerosis | 19.37 | 9.93 | 38 | 322873 | 22244 | 79399233 |
Prothrombin level abnormal | 19.36 | 9.93 | 11 | 322900 | 173 | 79421304 |
Chordae tendinae rupture | 19.34 | 9.93 | 8 | 322903 | 59 | 79421418 |
Catheter site mass | 19.34 | 9.93 | 8 | 322903 | 59 | 79421418 |
Xanthopsia | 19.30 | 9.93 | 14 | 322897 | 341 | 79421136 |
Paradoxical drug reaction | 19.28 | 9.93 | 3 | 322908 | 7182 | 79414295 |
Splenic rupture | 19.26 | 9.93 | 35 | 322876 | 2394 | 79419083 |
Haemorrhagic ovarian cyst | 19.24 | 9.93 | 18 | 322893 | 632 | 79420845 |
Cardiotoxicity | 19.17 | 9.93 | 13 | 322898 | 12226 | 79409251 |
Hyperglycaemia | 19.15 | 9.93 | 187 | 322724 | 70148 | 79351329 |
Post procedural haematoma | 19.13 | 9.93 | 35 | 322876 | 2407 | 79419070 |
Intervertebral disc protrusion | 19.09 | 9.93 | 42 | 322869 | 23579 | 79397898 |
Iron deficiency anaemia | 19.08 | 9.93 | 173 | 322738 | 25499 | 79395978 |
Osteonecrosis of jaw | 19.06 | 9.93 | 100 | 322811 | 43126 | 79378351 |
Food allergy | 19.05 | 9.93 | 10 | 322901 | 10814 | 79410663 |
Anastomotic infection | 19.00 | 9.93 | 10 | 322901 | 134 | 79421343 |
Eschar | 18.94 | 9.93 | 25 | 322886 | 1293 | 79420184 |
N-terminal prohormone brain natriuretic peptide increased | 18.92 | 9.93 | 52 | 322859 | 4703 | 79416774 |
Adrenal insufficiency | 18.89 | 9.93 | 56 | 322855 | 28431 | 79393046 |
Chronic sinusitis | 18.89 | 9.93 | 15 | 322896 | 13011 | 79408466 |
Gait disturbance | 18.82 | 9.93 | 669 | 322242 | 206837 | 79214640 |
Adverse drug reaction | 18.72 | 9.93 | 175 | 322736 | 66217 | 79355260 |
Medical device site haematoma | 18.72 | 9.93 | 7 | 322904 | 38 | 79421439 |
Catheter site dryness | 18.72 | 9.93 | 7 | 322904 | 38 | 79421439 |
Creatinine renal clearance decreased | 18.69 | 9.93 | 30 | 322881 | 18972 | 79402505 |
Cardiac ventricular thrombosis | 18.67 | 9.93 | 29 | 322882 | 1744 | 79419733 |
Polyneuropathy | 18.66 | 9.93 | 44 | 322867 | 24107 | 79397370 |
Thyroid haemorrhage | 18.66 | 9.93 | 9 | 322902 | 99 | 79421378 |
Large intestine polyp | 18.57 | 9.93 | 101 | 322810 | 12607 | 79408870 |
Right ventricular enlargement | 18.48 | 9.93 | 18 | 322893 | 665 | 79420812 |
Erythema | 18.45 | 9.93 | 728 | 322183 | 222562 | 79198915 |
Exposure to toxic agent | 18.41 | 9.93 | 7 | 322904 | 9151 | 79412326 |
Blood pressure diastolic increased | 18.40 | 9.93 | 19 | 322892 | 14523 | 79406954 |
Vitamin K decreased | 18.37 | 9.93 | 8 | 322903 | 68 | 79421409 |
Akathisia | 18.32 | 9.93 | 16 | 322895 | 13243 | 79408234 |
Hyperthyroidism | 18.24 | 9.93 | 153 | 322758 | 22056 | 79399421 |
Labelled drug-disease interaction medication error | 18.09 | 9.93 | 13 | 322898 | 312 | 79421165 |
Wound haemorrhage | 18.07 | 9.93 | 47 | 322864 | 4114 | 79417363 |
Infusion site discharge | 18.03 | 9.93 | 17 | 322894 | 603 | 79420874 |
Gastrointestinal erosion | 17.95 | 9.93 | 22 | 322889 | 1056 | 79420421 |
Anger | 17.94 | 9.93 | 26 | 322885 | 17136 | 79404341 |
Ear infection | 17.93 | 9.93 | 75 | 322836 | 34357 | 79387120 |
Hernia repair | 17.84 | 9.93 | 31 | 322880 | 2047 | 79419430 |
Prothrombin time shortened | 17.81 | 9.93 | 40 | 322871 | 3188 | 79418289 |
Cardiomegaly | 17.79 | 9.93 | 174 | 322737 | 26178 | 79395299 |
Peripheral sensory neuropathy | 17.68 | 9.93 | 16 | 322895 | 13017 | 79408460 |
Cholecystitis chronic | 17.66 | 9.93 | 9 | 322902 | 9897 | 79411580 |
No adverse event | 17.57 | 9.93 | 84 | 322827 | 37108 | 79384369 |
Weight increased | 17.53 | 9.93 | 931 | 321980 | 276455 | 79145022 |
Prothrombin level decreased | 17.46 | 9.93 | 27 | 322884 | 1617 | 79419860 |
Blood pressure systolic increased | 17.45 | 9.93 | 180 | 322731 | 66806 | 79354671 |
Injection site discharge | 17.43 | 9.93 | 19 | 322892 | 803 | 79420674 |
Skin exfoliation | 17.42 | 9.93 | 141 | 322770 | 54959 | 79366518 |
Alanine aminotransferase increased | 17.40 | 9.93 | 513 | 322398 | 162057 | 79259420 |
Brain stem haemorrhage | 17.39 | 9.93 | 27 | 322884 | 1623 | 79419854 |
Upper airway obstruction | 17.38 | 9.93 | 25 | 322886 | 1403 | 79420074 |
Joint dislocation | 17.37 | 9.93 | 26 | 322885 | 16913 | 79404564 |
Infusion site abscess | 17.36 | 9.93 | 11 | 322900 | 213 | 79421264 |
Drug specific antibody present | 17.35 | 9.93 | 3 | 322908 | 6649 | 79414828 |
Upper respiratory tract infection | 17.34 | 9.93 | 262 | 322649 | 90906 | 79330571 |
Spinal osteoarthritis | 17.34 | 9.93 | 26 | 322885 | 16901 | 79404576 |
Device physical property issue | 17.29 | 9.93 | 35 | 322876 | 2595 | 79418882 |
Colitis ulcerative | 17.28 | 9.93 | 77 | 322834 | 34665 | 79386812 |
Cerebral artery embolism | 17.28 | 9.93 | 29 | 322882 | 1862 | 79419615 |
Thoracic haemorrhage | 17.27 | 9.93 | 11 | 322900 | 215 | 79421262 |
Agranulocytosis | 17.27 | 9.93 | 109 | 322802 | 44921 | 79376556 |
Right ventricular diastolic collapse | 17.25 | 9.93 | 8 | 322903 | 80 | 79421397 |
Pulmonary arterial pressure abnormal | 17.23 | 9.93 | 18 | 322893 | 724 | 79420753 |
Back pain | 17.21 | 9.93 | 1032 | 321879 | 303148 | 79118329 |
Burning sensation | 17.20 | 9.93 | 153 | 322758 | 58479 | 79362998 |
Implantable defibrillator replacement | 17.11 | 9.93 | 5 | 322906 | 10 | 79421467 |
Refusal of treatment by patient | 17.09 | 9.93 | 77 | 322834 | 8914 | 79412563 |
Sickle cell anaemia | 17.04 | 9.93 | 17 | 322894 | 647 | 79420830 |
Mitral valve thickening | 17.01 | 9.93 | 14 | 322897 | 413 | 79421064 |
Mitral valve repair | 16.95 | 9.93 | 12 | 322899 | 281 | 79421196 |
Catheter site nodule | 16.88 | 9.93 | 7 | 322904 | 52 | 79421425 |
Diabetes mellitus | 16.79 | 9.93 | 220 | 322691 | 78170 | 79343307 |
Colorectal cancer | 16.75 | 9.93 | 7 | 322904 | 8640 | 79412837 |
Synovial cyst | 16.71 | 9.93 | 10 | 322901 | 10055 | 79411422 |
Acute hepatic failure | 16.69 | 9.93 | 64 | 322847 | 30049 | 79391428 |
Puncture site haematoma | 16.66 | 9.93 | 10 | 322901 | 175 | 79421302 |
Nephrosclerosis | 16.63 | 9.93 | 28 | 322883 | 1802 | 79419675 |
Ovarian cyst | 16.62 | 9.93 | 16 | 322895 | 12639 | 79408838 |
Proctalgia | 16.51 | 9.93 | 10 | 322901 | 9991 | 79411486 |
Hemiparesis | 16.49 | 9.93 | 209 | 322702 | 33524 | 79387953 |
Hyponatraemic syndrome | 16.48 | 9.93 | 18 | 322893 | 762 | 79420715 |
Haemorrhage urinary tract | 16.48 | 9.93 | 33 | 322878 | 2428 | 79419049 |
Pulmonary calcification | 16.48 | 9.93 | 14 | 322897 | 432 | 79421045 |
Hypochromasia | 16.37 | 9.93 | 17 | 322894 | 679 | 79420798 |
Demyelination | 16.35 | 9.93 | 6 | 322905 | 8017 | 79413460 |
Progressive multifocal leukoencephalopathy | 16.34 | 9.93 | 37 | 322874 | 20563 | 79400914 |
Cardiac murmur | 16.34 | 9.93 | 115 | 322796 | 15709 | 79405768 |
Anal fistula | 16.32 | 9.93 | 4 | 322907 | 6940 | 79414537 |
Body temperature increased | 16.28 | 9.93 | 109 | 322802 | 44311 | 79377166 |
Ulnar nerve palsy | 16.21 | 9.93 | 5 | 322906 | 13 | 79421464 |
Lip haemorrhage | 16.17 | 9.93 | 22 | 322889 | 1172 | 79420305 |
Breast cancer | 16.13 | 9.93 | 76 | 322835 | 33705 | 79387772 |
Glaucoma | 16.08 | 9.93 | 35 | 322876 | 19726 | 79401751 |
Scleroderma | 16.04 | 9.93 | 54 | 322857 | 5456 | 79416021 |
Angiodysplasia | 15.99 | 9.93 | 21 | 322890 | 1081 | 79420396 |
Oliguria | 15.96 | 9.93 | 117 | 322794 | 16192 | 79405285 |
Delusion | 15.94 | 9.93 | 37 | 322874 | 20386 | 79401091 |
Mitral valve stenosis | 15.94 | 9.93 | 22 | 322889 | 1188 | 79420289 |
Catheter site oedema | 15.90 | 9.93 | 8 | 322903 | 97 | 79421380 |
Venous thrombosis | 15.89 | 9.93 | 64 | 322847 | 7052 | 79414425 |
Mitral valve disease | 15.87 | 9.93 | 38 | 322873 | 3159 | 79418318 |
Craniotomy | 15.84 | 9.93 | 14 | 322897 | 456 | 79421021 |
Tongue disorder | 15.79 | 9.93 | 20 | 322891 | 13955 | 79407522 |
Oesophageal ulcer | 15.79 | 9.93 | 63 | 322848 | 6912 | 79414565 |
Oesophageal carcinoma | 15.78 | 9.93 | 13 | 322898 | 11071 | 79410406 |
Metastases to lung | 15.77 | 9.93 | 31 | 322880 | 18132 | 79403345 |
Cardioactive drug level below therapeutic | 15.70 | 9.93 | 5 | 322906 | 15 | 79421462 |
Bone pain | 15.69 | 9.93 | 147 | 322764 | 55595 | 79365882 |
Cardiac failure high output | 15.68 | 9.93 | 12 | 322899 | 318 | 79421159 |
Incision site haematoma | 15.65 | 9.93 | 9 | 322902 | 145 | 79421332 |
Post transplant lymphoproliferative disorder | 15.64 | 9.93 | 14 | 322897 | 11450 | 79410027 |
Catheter site erosion | 15.64 | 9.93 | 7 | 322904 | 64 | 79421413 |
Hemianopia homonymous | 15.63 | 9.93 | 23 | 322888 | 1318 | 79420159 |
Atrioventricular block complete | 15.60 | 9.93 | 118 | 322793 | 16492 | 79404985 |
Coronary artery bypass | 15.57 | 9.93 | 57 | 322854 | 6005 | 79415472 |
Abdominal cavity drainage | 15.57 | 9.93 | 18 | 322893 | 812 | 79420665 |
Large intestinal ulcer haemorrhage | 15.55 | 9.93 | 12 | 322899 | 322 | 79421155 |
Encephalomalacia | 15.51 | 9.93 | 22 | 322889 | 1219 | 79420258 |
Intervertebral disc degeneration | 15.45 | 9.93 | 25 | 322886 | 15760 | 79405717 |
Oral disorder | 15.44 | 9.93 | 11 | 322900 | 10084 | 79411393 |
Abdominal pain upper | 15.33 | 9.93 | 745 | 322166 | 223074 | 79198403 |
Coma scale normal | 15.30 | 9.93 | 4 | 322907 | 4 | 79421473 |
Low cardiac output syndrome | 15.30 | 9.93 | 20 | 322891 | 1025 | 79420452 |
Klebsiella infection | 15.29 | 9.93 | 25 | 322886 | 15695 | 79405782 |
Cardiac output increased | 15.27 | 9.93 | 11 | 322900 | 265 | 79421212 |
Odynophagia | 15.26 | 9.93 | 14 | 322897 | 11313 | 79410164 |
Cardiac output decreased | 15.24 | 9.93 | 27 | 322884 | 1811 | 79419666 |
Liver abscess | 15.21 | 9.93 | 3 | 322908 | 6051 | 79415426 |
Blood viscosity increased | 15.17 | 9.93 | 12 | 322899 | 334 | 79421143 |
Visual impairment | 15.14 | 9.93 | 272 | 322639 | 91859 | 79329618 |
Chronic respiratory failure | 15.08 | 9.93 | 36 | 322875 | 2986 | 79418491 |
Metastases to central nervous system | 15.05 | 9.93 | 27 | 322884 | 16348 | 79405129 |
Coagulation factor deficiency | 15.02 | 9.93 | 9 | 322902 | 157 | 79421320 |
Gastrointestinal toxicity | 15.02 | 9.93 | 7 | 322904 | 8102 | 79413375 |
Application site irritation | 14.95 | 9.93 | 26 | 322885 | 1718 | 79419759 |
Ovarian cyst ruptured | 14.94 | 9.93 | 19 | 322892 | 947 | 79420530 |
Device adhesion issue | 14.92 | 9.93 | 5 | 322906 | 7070 | 79414407 |
N-telopeptide urine increased | 14.90 | 9.93 | 6 | 322905 | 41 | 79421436 |
Aortic bruit | 14.89 | 9.93 | 11 | 322900 | 276 | 79421201 |
Dermatitis allergic | 14.85 | 9.93 | 32 | 322879 | 18098 | 79403379 |
Subcapsular renal haematoma | 14.83 | 9.93 | 17 | 322894 | 760 | 79420717 |
Balloon atrial septostomy | 14.77 | 9.93 | 8 | 322903 | 114 | 79421363 |
Muscle rigidity | 14.75 | 9.93 | 37 | 322874 | 19845 | 79401632 |
Renal disorder | 14.69 | 9.93 | 246 | 322665 | 41859 | 79379618 |
Parkinsonism | 14.66 | 9.93 | 28 | 322883 | 16556 | 79404921 |
Injection site mass | 14.63 | 9.93 | 38 | 322873 | 20146 | 79401331 |
Liver function test abnormal | 14.57 | 9.93 | 353 | 322558 | 64122 | 79357355 |
Anal abscess | 14.56 | 9.93 | 10 | 322901 | 9345 | 79412132 |
Left atrial enlargement | 14.56 | 9.93 | 21 | 322890 | 1182 | 79420295 |
Device related thrombosis | 14.53 | 9.93 | 33 | 322878 | 2650 | 79418827 |
Neutrophilia | 14.52 | 9.93 | 7 | 322904 | 7944 | 79413533 |
Aphasia | 14.51 | 9.93 | 268 | 322643 | 46464 | 79375013 |
Arteriovenous fistula operation | 14.49 | 9.93 | 12 | 322899 | 357 | 79421120 |
Dry skin | 14.49 | 9.93 | 191 | 322720 | 67804 | 79353673 |
Alanine aminotransferase abnormal | 14.45 | 9.93 | 9 | 322902 | 8858 | 79412619 |
Depressed level of consciousness | 14.45 | 9.93 | 290 | 322621 | 96362 | 79325115 |
Alkalosis hypokalaemic | 14.41 | 9.93 | 5 | 322906 | 21 | 79421456 |
Blood uric acid increased | 14.33 | 9.93 | 98 | 322813 | 13262 | 79408215 |
Skin reaction | 14.32 | 9.93 | 27 | 322884 | 16041 | 79405436 |
Aneurysm | 14.31 | 9.93 | 39 | 322872 | 3509 | 79417968 |
Implantable defibrillator insertion | 14.27 | 9.93 | 19 | 322892 | 991 | 79420486 |
Herpes simplex | 14.23 | 9.93 | 17 | 322894 | 12170 | 79409307 |
Dyspnoea at rest | 14.23 | 9.93 | 63 | 322848 | 7239 | 79414238 |
Vaginal haemorrhage | 14.22 | 9.93 | 143 | 322768 | 21674 | 79399803 |
Affective disorder | 14.19 | 9.93 | 8 | 322903 | 8311 | 79413166 |
Euglycaemic diabetic ketoacidosis | 14.15 | 9.93 | 5 | 322906 | 6839 | 79414638 |
Muscle twitching | 14.13 | 9.93 | 52 | 322859 | 24712 | 79396765 |
Aplasia | 14.10 | 9.93 | 7 | 322904 | 7813 | 79413664 |
Aortic valve incompetence | 14.10 | 9.93 | 76 | 322835 | 9454 | 79412023 |
SARS-CoV-2 test positive | 14.05 | 9.93 | 16 | 322895 | 11700 | 79409777 |
Medical device site haemorrhage | 14.04 | 9.93 | 9 | 322902 | 178 | 79421299 |
Gastrointestinal ulcer | 14.02 | 9.93 | 38 | 322873 | 3408 | 79418069 |
Muscle strain | 14.00 | 9.93 | 76 | 322835 | 9479 | 79411998 |
Peptic ulcer | 13.92 | 9.93 | 56 | 322855 | 6167 | 79415310 |
Procalcitonin abnormal | 13.92 | 9.93 | 12 | 322899 | 378 | 79421099 |
Metastases to lymph nodes | 13.83 | 9.93 | 13 | 322898 | 10384 | 79411093 |
Incarcerated hernia | 13.81 | 9.93 | 12 | 322899 | 382 | 79421095 |
Haemodialysis | 13.79 | 9.93 | 123 | 322788 | 18045 | 79403432 |
Paraesthesia oral | 13.75 | 9.93 | 40 | 322871 | 20431 | 79401046 |
Splenic haematoma | 13.73 | 9.93 | 11 | 322900 | 312 | 79421165 |
Tricuspid valve incompetence | 13.72 | 9.93 | 131 | 322780 | 19581 | 79401896 |
Intestinal haemorrhage | 13.72 | 9.93 | 57 | 322854 | 6369 | 79415108 |
Polyomavirus-associated nephropathy | 13.70 | 9.93 | 3 | 322908 | 5624 | 79415853 |
Cardioactive drug level above therapeutic | 13.70 | 9.93 | 10 | 322901 | 246 | 79421231 |
Left ventricular enlargement | 13.69 | 9.93 | 16 | 322895 | 730 | 79420747 |
Strangury | 13.69 | 9.93 | 9 | 322902 | 186 | 79421291 |
Multiple injuries | 13.69 | 9.93 | 38 | 322873 | 3457 | 79418020 |
Breast cancer stage I | 13.68 | 9.93 | 5 | 322906 | 6695 | 79414782 |
Dysphagia | 13.67 | 9.93 | 383 | 322528 | 121753 | 79299724 |
Stress cardiomyopathy | 13.67 | 9.93 | 15 | 322896 | 11151 | 79410326 |
Retching | 13.64 | 9.93 | 119 | 322792 | 17348 | 79404129 |
Vaginal haematoma | 13.64 | 9.93 | 8 | 322903 | 134 | 79421343 |
Nocturnal dyspnoea | 13.63 | 9.93 | 24 | 322887 | 1602 | 79419875 |
Mitral valve incompetence | 13.55 | 9.93 | 176 | 322735 | 28389 | 79393088 |
Congenital tracheomalacia | 13.54 | 9.93 | 3 | 322908 | 0 | 79421477 |
Application site pruritus | 13.54 | 9.93 | 40 | 322871 | 3770 | 79417707 |
Colon cancer | 13.54 | 9.93 | 103 | 322808 | 14420 | 79407057 |
Eye infection | 13.53 | 9.93 | 17 | 322894 | 11903 | 79409574 |
Gastrointestinal pain | 13.49 | 9.93 | 12 | 322899 | 9843 | 79411634 |
Cardioactive drug level decreased | 13.48 | 9.93 | 9 | 322902 | 191 | 79421286 |
Gastrointestinal angiodysplasia | 13.43 | 9.93 | 19 | 322892 | 1050 | 79420427 |
IgA nephropathy | 13.42 | 9.93 | 25 | 322886 | 1743 | 79419734 |
Micturition urgency | 13.36 | 9.93 | 19 | 322892 | 12622 | 79408855 |
Bullous haemorrhagic dermatosis | 13.36 | 9.93 | 7 | 322904 | 93 | 79421384 |
Arterial haemorrhage | 13.32 | 9.93 | 31 | 322880 | 2530 | 79418947 |
Nodule | 13.31 | 9.93 | 48 | 322863 | 22946 | 79398531 |
Radiation proctitis | 13.28 | 9.93 | 8 | 322903 | 141 | 79421336 |
Stent placement | 13.27 | 9.93 | 57 | 322854 | 6463 | 79415014 |
Herpes virus infection | 13.19 | 9.93 | 6 | 322905 | 7043 | 79414434 |
Cervical cord compression | 13.17 | 9.93 | 12 | 322899 | 407 | 79421070 |
Diabetes mellitus inadequate control | 13.17 | 9.93 | 52 | 322859 | 24212 | 79397265 |
Purple glove syndrome | 13.16 | 9.93 | 10 | 322901 | 262 | 79421215 |
Circulatory collapse | 13.12 | 9.93 | 220 | 322691 | 37448 | 79384029 |
Headache | 13.11 | 9.93 | 2914 | 319997 | 650858 | 78770619 |
Gastrointestinal angiectasia | 13.00 | 9.93 | 12 | 322899 | 414 | 79421063 |
Female genital tract fistula | 13.00 | 9.93 | 4 | 322907 | 5971 | 79415506 |
Treatment noncompliance | 12.99 | 9.93 | 290 | 322621 | 51978 | 79369499 |
Joint effusion | 12.99 | 9.93 | 34 | 322877 | 17980 | 79403497 |
Drain placement | 12.99 | 9.93 | 8 | 322903 | 147 | 79421330 |
Application site odour | 12.96 | 9.93 | 5 | 322906 | 30 | 79421447 |
Mydriasis | 12.96 | 9.93 | 33 | 322878 | 17610 | 79403867 |
Intra-abdominal fluid collection | 12.93 | 9.93 | 35 | 322876 | 3137 | 79418340 |
Haematoma infection | 12.90 | 9.93 | 23 | 322888 | 1550 | 79419927 |
Blood cholinesterase decreased | 12.87 | 9.93 | 10 | 322901 | 271 | 79421206 |
Venous haemorrhage | 12.85 | 9.93 | 11 | 322900 | 343 | 79421134 |
Investigation | 12.82 | 9.93 | 29 | 322882 | 2322 | 79419155 |
Heartland virus infection | 12.82 | 9.93 | 5 | 322906 | 31 | 79421446 |
Uterine haemorrhage | 12.82 | 9.93 | 33 | 322878 | 2870 | 79418607 |
Human herpesvirus 6 infection | 12.80 | 9.93 | 3 | 322908 | 5367 | 79416110 |
Hypopnoea | 12.77 | 9.93 | 49 | 322862 | 5280 | 79416197 |
Ketoacidosis | 12.76 | 9.93 | 8 | 322903 | 7846 | 79413631 |
Disease progression | 12.76 | 9.93 | 613 | 322298 | 183749 | 79237728 |
Hepatic rupture | 12.73 | 9.93 | 7 | 322904 | 103 | 79421374 |
Neuralgia | 12.70 | 9.93 | 81 | 322830 | 33303 | 79388174 |
Sopor | 12.69 | 9.93 | 196 | 322715 | 32814 | 79388663 |
Catheter site urticaria | 12.69 | 9.93 | 5 | 322906 | 32 | 79421445 |
Cerebellar infarction | 12.68 | 9.93 | 38 | 322873 | 3609 | 79417868 |
Vaginal infection | 12.68 | 9.93 | 4 | 322907 | 5876 | 79415601 |
Myocardial infarction | 12.66 | 9.93 | 887 | 322024 | 183242 | 79238235 |
Hepatic infarction | 12.61 | 9.93 | 17 | 322894 | 898 | 79420579 |
Blepharospasm | 12.58 | 9.93 | 4 | 322907 | 5847 | 79415630 |
Ischaemic hepatitis | 12.58 | 9.93 | 38 | 322873 | 3626 | 79417851 |
Exophthalmos | 12.56 | 9.93 | 24 | 322887 | 1706 | 79419771 |
Valvuloplasty cardiac | 12.56 | 9.93 | 4 | 322907 | 12 | 79421465 |
Procalcitonin | 12.56 | 9.93 | 4 | 322907 | 12 | 79421465 |
Arterial rupture | 12.54 | 9.93 | 16 | 322895 | 800 | 79420677 |
Skin fissures | 12.52 | 9.93 | 21 | 322890 | 13052 | 79408425 |
X-ray abnormal | 12.45 | 9.93 | 4 | 322907 | 5809 | 79415668 |
Coagulation factor decreased | 12.42 | 9.93 | 9 | 322902 | 219 | 79421258 |
Behaviour disorder | 12.41 | 9.93 | 5 | 322906 | 6308 | 79415169 |
Mental disorder | 12.40 | 9.93 | 75 | 322836 | 31227 | 79390250 |
Enterocolitis | 12.40 | 9.93 | 25 | 322886 | 14487 | 79406990 |
Pelvic haemorrhage | 12.40 | 9.93 | 8 | 322903 | 160 | 79421317 |
Bovine tuberculosis | 12.40 | 9.93 | 8 | 322903 | 160 | 79421317 |
Protein-losing gastroenteropathy | 12.39 | 9.93 | 14 | 322897 | 616 | 79420861 |
Rehabilitation therapy | 12.37 | 9.93 | 25 | 322886 | 1852 | 79419625 |
Memory impairment | 12.35 | 9.93 | 351 | 322560 | 111383 | 79310094 |
Disease complication | 12.33 | 9.93 | 46 | 322865 | 4891 | 79416586 |
Hemiplegia | 12.31 | 9.93 | 103 | 322808 | 14836 | 79406641 |
Renal infarct | 12.31 | 9.93 | 31 | 322880 | 2660 | 79418817 |
Proteinuria | 12.29 | 9.93 | 79 | 322832 | 32423 | 79389054 |
Eyelid ptosis | 12.28 | 9.93 | 16 | 322895 | 11028 | 79410449 |
Granulocytopenia | 12.26 | 9.93 | 17 | 322894 | 11414 | 79410063 |
Intracranial haematoma | 12.25 | 9.93 | 17 | 322894 | 923 | 79420554 |
Hernia hiatus repair | 12.21 | 9.93 | 6 | 322905 | 69 | 79421408 |
Cytopenia | 12.17 | 9.93 | 42 | 322869 | 20341 | 79401136 |
Medication error | 12.14 | 9.93 | 364 | 322547 | 68278 | 79353199 |
Encephalitis | 12.13 | 9.93 | 26 | 322885 | 14734 | 79406743 |
Vomiting | 12.08 | 9.93 | 2446 | 320465 | 663382 | 78758095 |
Oropharyngeal discomfort | 12.06 | 9.93 | 7 | 322904 | 7159 | 79414318 |
Prostatic haemorrhage | 12.06 | 9.93 | 8 | 322903 | 168 | 79421309 |
Mania | 12.03 | 9.93 | 36 | 322875 | 18224 | 79403253 |
Aortic aneurysm rupture | 12.02 | 9.93 | 20 | 322891 | 1275 | 79420202 |
Increased tendency to bruise | 11.97 | 9.93 | 78 | 322833 | 10386 | 79411091 |
Mucormycosis | 11.97 | 9.93 | 10 | 322901 | 8459 | 79413018 |
Stent-graft endoleak | 11.96 | 9.93 | 5 | 322906 | 38 | 79421439 |
Pseudomonal sepsis | 11.95 | 9.93 | 5 | 322906 | 6169 | 79415308 |
Therapy interrupted | 11.95 | 9.93 | 76 | 322835 | 31265 | 79390212 |
Right ventricular systolic pressure increased | 11.94 | 9.93 | 17 | 322894 | 945 | 79420532 |
Chronic cutaneous lupus erythematosus | 11.91 | 9.93 | 12 | 322899 | 462 | 79421015 |
Dental pulp disorder | 11.88 | 9.93 | 4 | 322907 | 15 | 79421462 |
Personality disorder | 11.86 | 9.93 | 5 | 322906 | 6141 | 79415336 |
Blood potassium decreased | 11.86 | 9.93 | 259 | 322652 | 46253 | 79375224 |
Vena cava thrombosis | 11.86 | 9.93 | 32 | 322879 | 2863 | 79418614 |
Abnormal loss of weight | 11.86 | 9.93 | 66 | 322845 | 8310 | 79413167 |
Photophobia | 11.78 | 9.93 | 43 | 322868 | 20485 | 79400992 |
Hepatic encephalopathy | 11.76 | 9.93 | 54 | 322857 | 24112 | 79397365 |
Premature labour | 11.75 | 9.93 | 10 | 322901 | 8380 | 79413097 |
Diastolic hypotension | 11.74 | 9.93 | 8 | 322903 | 176 | 79421301 |
Antiphospholipid antibodies positive | 11.71 | 9.93 | 15 | 322896 | 753 | 79420724 |
Mediastinal haemorrhage | 11.70 | 9.93 | 6 | 322905 | 76 | 79421401 |
Emergency care examination | 11.69 | 9.93 | 7 | 322904 | 122 | 79421355 |
Pre-eclampsia | 11.68 | 9.93 | 7 | 322904 | 7034 | 79414443 |
Metastases to liver | 11.66 | 9.93 | 67 | 322844 | 28247 | 79393230 |
Spinal cord compression | 11.66 | 9.93 | 54 | 322857 | 6323 | 79415154 |
Traumatic haemorrhage | 11.59 | 9.93 | 20 | 322891 | 1313 | 79420164 |
Injection site bruising | 11.59 | 9.93 | 108 | 322803 | 40894 | 79380583 |
Hepatitis B | 11.58 | 9.93 | 10 | 322901 | 8322 | 79413155 |
Fibrinous bronchitis | 11.53 | 9.93 | 5 | 322906 | 42 | 79421435 |
Blood pressure immeasurable | 11.53 | 9.93 | 26 | 322885 | 2078 | 79419399 |
Scrotal oedema | 11.52 | 9.93 | 22 | 322889 | 1563 | 79419914 |
Product complaint | 11.52 | 9.93 | 93 | 322818 | 13256 | 79408221 |
Cushingoid | 11.51 | 9.93 | 13 | 322898 | 9539 | 79411938 |
5-hydroxyindolacetic acid increased | 11.49 | 9.93 | 4 | 322907 | 17 | 79421460 |
Localised oedema | 11.49 | 9.93 | 63 | 322848 | 7889 | 79413588 |
Biliary tract operation | 11.47 | 9.93 | 3 | 322908 | 3 | 79421474 |
Optic neuritis | 11.42 | 9.93 | 13 | 322898 | 9507 | 79411970 |
Cytomegalovirus chorioretinitis | 11.37 | 9.93 | 4 | 322907 | 5486 | 79415991 |
Arteriovenous fistula | 11.37 | 9.93 | 20 | 322891 | 1334 | 79420143 |
Eosinophilia | 11.34 | 9.93 | 123 | 322788 | 45222 | 79376255 |
Hepatic vein thrombosis | 11.33 | 9.93 | 9 | 322902 | 252 | 79421225 |
Bladder necrosis | 11.31 | 9.93 | 4 | 322907 | 18 | 79421459 |
Emotional disorder | 11.28 | 9.93 | 26 | 322885 | 14361 | 79407116 |
Malignant melanoma | 11.27 | 9.93 | 27 | 322884 | 14714 | 79406763 |
Product dose omission in error | 11.25 | 9.93 | 9 | 322902 | 7779 | 79413698 |
Haemorrhoids | 11.22 | 9.93 | 173 | 322738 | 28955 | 79392522 |
Electrolyte imbalance | 11.21 | 9.93 | 76 | 322835 | 30805 | 79390672 |
Heart and lung transplant | 11.21 | 9.93 | 8 | 322903 | 190 | 79421287 |
Nephrogenic systemic fibrosis | 11.15 | 9.93 | 52 | 322859 | 6108 | 79415369 |
Stevens-Johnson syndrome | 11.14 | 9.93 | 103 | 322808 | 39063 | 79382414 |
Coagulation factor V level increased | 11.14 | 9.93 | 5 | 322906 | 46 | 79421431 |
Mitral perforation | 11.13 | 9.93 | 4 | 322907 | 19 | 79421458 |
Peripheral ischaemia | 11.13 | 9.93 | 71 | 322840 | 9386 | 79412091 |
Myoclonus | 11.10 | 9.93 | 66 | 322845 | 27594 | 79393883 |
Thyroiditis acute | 11.10 | 9.93 | 8 | 322903 | 193 | 79421284 |
Gastrointestinal polyp haemorrhage | 11.09 | 9.93 | 12 | 322899 | 503 | 79420974 |
Respiratory arrest | 11.08 | 9.93 | 165 | 322746 | 57385 | 79364092 |
Tardive dyskinesia | 11.06 | 9.93 | 16 | 322895 | 10555 | 79410922 |
Injection site pustule | 11.05 | 9.93 | 6 | 322905 | 86 | 79421391 |
Blood urine | 11.04 | 9.93 | 16 | 322895 | 904 | 79420573 |
Personality change | 11.03 | 9.93 | 15 | 322896 | 10155 | 79411322 |
Acquired oesophageal web | 11.03 | 9.93 | 10 | 322901 | 337 | 79421140 |
Heart disease congenital | 11.03 | 9.93 | 13 | 322898 | 599 | 79420878 |
Vessel puncture site haemorrhage | 10.99 | 9.93 | 8 | 322903 | 196 | 79421281 |
Burning feet syndrome | 10.99 | 9.93 | 8 | 322903 | 196 | 79421281 |
Complication of device insertion | 10.98 | 9.93 | 6 | 322905 | 6344 | 79415133 |
Inadequate diet | 10.98 | 9.93 | 9 | 322902 | 264 | 79421213 |
Amenorrhoea | 10.98 | 9.93 | 9 | 322902 | 7683 | 79413794 |
Concomitant disease aggravated | 10.97 | 9.93 | 91 | 322820 | 13076 | 79408401 |
Post procedural complication | 10.96 | 9.93 | 146 | 322765 | 23683 | 79397794 |
Skin discolouration | 10.95 | 9.93 | 230 | 322681 | 40804 | 79380673 |
Lip injury | 10.93 | 9.93 | 18 | 322893 | 1138 | 79420339 |
Salivary hypersecretion | 10.92 | 9.93 | 26 | 322885 | 14198 | 79407279 |
Dysaesthesia | 10.91 | 9.93 | 5 | 322906 | 5843 | 79415634 |
Polyp | 10.90 | 9.93 | 63 | 322848 | 8044 | 79413433 |
Septic shock | 10.88 | 9.93 | 397 | 322514 | 122404 | 79299073 |
Hyperthermia | 10.88 | 9.93 | 37 | 322874 | 18000 | 79403477 |
Affect lability | 10.86 | 9.93 | 18 | 322893 | 11241 | 79410236 |
Anaesthesia | 10.86 | 9.93 | 12 | 322899 | 515 | 79420962 |
Femoral artery aneurysm | 10.85 | 9.93 | 8 | 322903 | 200 | 79421277 |
Thyrotoxic crisis | 10.82 | 9.93 | 19 | 322892 | 1265 | 79420212 |
Diuretic therapy | 10.82 | 9.93 | 8 | 322903 | 201 | 79421276 |
Infusion site pruritus | 10.81 | 9.93 | 39 | 322872 | 4079 | 79417398 |
Libido decreased | 10.81 | 9.93 | 4 | 322907 | 5317 | 79416160 |
Thromboembolectomy | 10.81 | 9.93 | 6 | 322905 | 90 | 79421387 |
Tendon disorder | 10.77 | 9.93 | 8 | 322903 | 7178 | 79414299 |
Therapeutic procedure | 10.74 | 9.93 | 15 | 322896 | 819 | 79420658 |
Urine output decreased | 10.74 | 9.93 | 116 | 322795 | 17906 | 79403571 |
Inhibitory drug interaction | 10.71 | 9.93 | 41 | 322870 | 4412 | 79417065 |
Hallucination, visual | 10.69 | 9.93 | 83 | 322828 | 32646 | 79388831 |
Bronchospasm | 10.69 | 9.93 | 58 | 322853 | 24801 | 79396676 |
Device dislocation | 10.69 | 9.93 | 156 | 322755 | 25814 | 79395663 |
Cardiac infection | 10.68 | 9.93 | 11 | 322900 | 435 | 79421042 |
Drug dose omission by device | 10.67 | 9.93 | 6 | 322905 | 6244 | 79415233 |
Parathyroid gland operation | 10.66 | 9.93 | 4 | 322907 | 22 | 79421455 |
Vision blurred | 10.63 | 9.93 | 337 | 322574 | 105561 | 79315916 |
Central nervous system lesion | 10.61 | 9.93 | 24 | 322887 | 13344 | 79408133 |
Colonoscopy | 10.60 | 9.93 | 24 | 322887 | 1923 | 79419554 |
Dysuria | 10.54 | 9.93 | 144 | 322767 | 50807 | 79370670 |
Spinal fusion surgery | 10.54 | 9.93 | 4 | 322907 | 5234 | 79416243 |
Bladder cancer | 10.50 | 9.93 | 42 | 322869 | 19484 | 79401993 |
Cystitis haemorrhagic | 10.49 | 9.93 | 13 | 322898 | 9159 | 79412318 |
Fistula | 10.46 | 9.93 | 23 | 322888 | 12917 | 79408560 |
Peripheral embolism | 10.45 | 9.93 | 24 | 322887 | 1942 | 79419535 |
Brain natriuretic peptide | 10.44 | 9.93 | 5 | 322906 | 54 | 79421423 |
Drug therapy | 10.42 | 9.93 | 18 | 322893 | 1183 | 79420294 |
Catheter site extravasation | 10.42 | 9.93 | 11 | 322900 | 448 | 79421029 |
Dysentery | 10.41 | 9.93 | 18 | 322893 | 1184 | 79420293 |
Delirium | 10.36 | 9.93 | 262 | 322649 | 84365 | 79337112 |
Post thrombotic syndrome | 10.35 | 9.93 | 13 | 322898 | 640 | 79420837 |
Blood glucose increased | 10.35 | 9.93 | 371 | 322540 | 114604 | 79306873 |
Aortic aneurysm | 10.31 | 9.93 | 64 | 322847 | 8382 | 79413095 |
Laryngitis | 10.30 | 9.93 | 32 | 322879 | 16007 | 79405470 |
Respiratory tract infection | 10.29 | 9.93 | 137 | 322774 | 48552 | 79372925 |
Subileus | 10.29 | 9.93 | 5 | 322906 | 5649 | 79415828 |
Postpartum venous thrombosis | 10.27 | 9.93 | 3 | 322908 | 6 | 79421471 |
Factor II mutation | 10.27 | 9.93 | 3 | 322908 | 6 | 79421471 |
Acquired Von Willebrand's disease | 10.27 | 9.93 | 3 | 322908 | 6 | 79421471 |
Acquired cardiac septal defect | 10.27 | 9.93 | 3 | 322908 | 6 | 79421471 |
Cerebellar embolism | 10.27 | 9.93 | 3 | 322908 | 6 | 79421471 |
Budd-Chiari syndrome | 10.25 | 9.93 | 6 | 322905 | 100 | 79421377 |
Onychomycosis | 10.22 | 9.93 | 11 | 322900 | 8250 | 79413227 |
Acquired phimosis | 10.21 | 9.93 | 5 | 322906 | 57 | 79421420 |
Hernia obstructive | 10.20 | 9.93 | 6 | 322905 | 101 | 79421376 |
Coagulation time abnormal | 10.20 | 9.93 | 8 | 322903 | 220 | 79421257 |
Immunosuppression | 10.15 | 9.93 | 23 | 322888 | 12780 | 79408697 |
Malaise | 10.15 | 9.93 | 2187 | 320724 | 487682 | 78933795 |
Panic attack | 10.14 | 9.93 | 57 | 322854 | 24159 | 79397318 |
Coordination abnormal | 10.11 | 9.93 | 36 | 322875 | 17276 | 79404201 |
Tricuspid valve replacement | 10.10 | 9.93 | 4 | 322907 | 26 | 79421451 |
Tricuspid valve repair | 10.10 | 9.93 | 4 | 322907 | 26 | 79421451 |
Breast haemorrhage | 10.07 | 9.93 | 7 | 322904 | 159 | 79421318 |
Basal ganglia haematoma | 10.06 | 9.93 | 5 | 322906 | 59 | 79421418 |
Nerve injury | 10.04 | 9.93 | 14 | 322897 | 9378 | 79412099 |
Eye haematoma | 10.00 | 9.93 | 7 | 322904 | 161 | 79421316 |
Pulmonary resection | 9.99 | 9.93 | 5 | 322906 | 60 | 79421417 |
None
Source | Code | Description |
---|---|---|
ATC | B01AA03 | BLOOD AND BLOOD FORMING ORGANS ANTITHROMBOTIC AGENTS ANTITHROMBOTIC AGENTS Vitamin K antagonists |
FDA EPC | N0000175476 | Vitamin K Antagonist |
CHEBI has role | CHEBI:33288 | rodenticides |
CHEBI has role | CHEBI:50249 | anticoagulants |
CHEBI has role | CHEBI:50390 | NAD(P)H dehydrogenase (quinone) inhibitors |
CHEBI has role | CHEBI:55347 | vitamin K antagonists |
FDA MoA | N0000175964 | Vitamin K Inhibitors |
MeSH PA | D000925 | Anticoagulants |
MeSH PA | D006401 | Hematologic Agents |
MeSH PA | D010575 | Pesticides |
MeSH PA | D012378 | Rodenticides |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Cerebral embolism | indication | 75543006 | DOID:4372 |
Deep venous thrombosis | indication | 128053003 | |
Pulmonary thromboembolism | indication | 233935004 | |
Thromboembolic disorder | indication | 371039008 | |
Thrombosis | indication | 439127006 | |
Prevention of deep vein thrombosis | indication | 439993001 | |
Thromboembolism due to Prosthetic Heart Valves | indication | ||
Myocardial Reinfarction Prevention | indication | ||
Prevention of Thromboembolism with Chronic Atrial Fibrillation | indication | ||
Deep Vein Thrombosis with Pulmonary Embolism | indication | ||
Pulmonary Thromboembolism Prevention | indication | ||
Thrombophilia | off-label use | 234467004 | DOID:2452 |
Heart Failure with Paroxysmal Atrial Fibrillation | off-label use | ||
Nutritional disorder | contraindication | 2492009 | DOID:374 |
Pericarditis | contraindication | 3238004 | DOID:1787 |
Necrosis | contraindication | 6574001 | |
Alcoholism | contraindication | 7200002 | |
Obstruction of bile duct | contraindication | 30144000 | |
Vasculitis | contraindication | 31996006 | DOID:865 |
Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
Gangrene | contraindication | 36024000 | |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Gastrointestinal ulcer | contraindication | 40845000 | |
Hypothyroidism | contraindication | 40930008 | DOID:1459 |
Secondary uterine inertia | contraindication | 43715006 | |
Tropical sprue | contraindication | 47384003 | DOID:10607 |
Nephrotic syndrome | contraindication | 52254009 | DOID:1184 |
Vitamin K deficiency | contraindication | 52675005 | DOID:11249 |
Threatened abortion | contraindication | 54048003 | DOID:9667 |
Hyperlipidemia | contraindication | 55822004 | DOID:1168 |
Hepatic failure | contraindication | 59927004 | |
Cerebrovascular disease | contraindication | 62914000 | DOID:6713 |
Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
Fatty stool | contraindication | 66187002 | |
Psychotic disorder | contraindication | 69322001 | |
Heparin-induced thrombocytopenia | contraindication | 73397007 | |
Gastrointestinal hemorrhage | contraindication | 74474003 | |
Protein C deficiency disease | contraindication | 76407009 | DOID:3756 |
Respiratory tract hemorrhage | contraindication | 95431003 | |
Disorder of connective tissue | contraindication | 105969002 | DOID:65 |
Polycythemia vera | contraindication | 109992005 | |
Procedure on central nervous system | contraindication | 118679007 | |
Intracranial aneurysm | contraindication | 128609009 | DOID:10941 |
Bleeding | contraindication | 131148009 | |
Impaired renal function disorder | contraindication | 197663003 | |
Eclampsia in pregnancy | contraindication | 198992004 | |
Local anesthetic intrathecal block | contraindication | 231249005 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Chronic diarrhea | contraindication | 236071009 | |
Edema | contraindication | 267038008 | |
Anemia | contraindication | 271737000 | DOID:2355 |
Cerebral hemorrhage | contraindication | 274100004 | |
Lumbar puncture | contraindication | 277762005 | |
Pregnancy, function | contraindication | 289908002 | |
Bacterial endocarditis | contraindication | 301183007 | |
Dissection of aorta | contraindication | 308546005 | |
Primary malignant neoplasm | contraindication | 372087000 | |
Surgical procedure on eye proper | contraindication | 373353005 | |
Pericardial effusion | contraindication | 373945007 | DOID:118 |
Fever | contraindication | 386661006 | |
Surgical procedure | contraindication | 387713003 | |
Severe diarrhea | contraindication | 409587002 | |
Traumatic injury | contraindication | 417746004 | |
Genitourinary tract hemorrhage | contraindication | 417941003 | |
Poor metabolizer due to cytochrome p450 CYP2C9 variant | contraindication | 424451001 | |
Hypertensive urgency | contraindication | 443482000 | |
Internal Hemorrhage | contraindication | ||
Indwelling Vascular Catheter | contraindication | ||
Cholesterol Embolism | contraindication | ||
Severe Diabetes Mellitus | contraindication | ||
Bleeding Risk Associated with Vitamin-K-Epoxide Reductase (Warfarin-Sensitive) Gene | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 4.96 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Vitamin K epoxide reductase complex subunit 1 | Enzyme | INHIBITOR | IC50 | 7 | WOMBAT-PK | CHEMBL | |||
Cytochrome P450 3A4 | Enzyme | Ki | 3.98 | WOMBAT-PK | |||||
Cytochrome P450 2C9 | Enzyme | Ki | 4.87 | WOMBAT-PK | |||||
Proprotein convertase subtilisin/kexin type 7 | Enzyme | IC50 | 4.61 | CHEMBL | |||||
Vitamin K epoxide reductase complex subunit 1-like protein 1 | Enzyme | Ki | 4.28 | SCIENTIFIC LITERATURE |
ID | Source |
---|---|
4019972 | VUID |
N0000148057 | NUI |
D00564 | KEGG_DRUG |
129-06-6 | SECONDARY_CAS_RN |
4018548 | VANDF |
4019972 | VANDF |
C0043031 | UMLSCUI |
CHEBI:10033 | CHEBI |
CHEMBL1464 | ChEMBL_ID |
DB00682 | DRUGBANK_ID |
CHEMBL1200879 | ChEMBL_ID |
D014859 | MESH_DESCRIPTOR_UI |
54678486 | PUBCHEM_CID |
6853 | IUPHAR_LIGAND_ID |
341 | INN_ID |
2610-86-8 | SECONDARY_CAS_RN |
5Q7ZVV76EI | UNII |
11289 | RXNORM |
1258 | MMSL |
5693 | MMSL |
d00022 | MMSL |
002084 | NDDF |
002085 | NDDF |
004065 | NDDF |
372756006 | SNOMEDCT_US |
41509001 | SNOMEDCT_US |
48603004 | SNOMEDCT_US |
63167009 | SNOMEDCT_US |
CHEMBL1200772 | ChEMBL_ID |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1712 | TABLET | 1 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1712 | TABLET | 1 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1713 | TABLET | 2 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1713 | TABLET | 2 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1714 | TABLET | 2.50 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1714 | TABLET | 2.50 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1715 | TABLET | 3 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1715 | TABLET | 3 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1716 | TABLET | 4 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1716 | TABLET | 4 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1718 | TABLET | 6 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1718 | TABLET | 6 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1720 | TABLET | 10 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1720 | TABLET | 10 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1721 | TABLET | 5 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1721 | TABLET | 5 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1723 | TABLET | 7.50 mg | ORAL | ANDA | 29 sections |
Warfarin Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1723 | TABLET | 7.50 mg | ORAL | ANDA | 29 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1211 | TABLET | 1 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1211 | TABLET | 1 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1212 | TABLET | 2 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1212 | TABLET | 2 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1213 | TABLET | 2.50 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1213 | TABLET | 2.50 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1214 | TABLET | 3 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1214 | TABLET | 3 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1215 | TABLET | 4 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1215 | TABLET | 4 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1216 | TABLET | 5 mg | ORAL | ANDA | 30 sections |
Jantoven | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0832-1216 | TABLET | 5 mg | ORAL | ANDA | 30 sections |