chlorquinaldol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| quinoline derivatives | 3095 | 72-80-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Local anti-infective agent used for skin, gastrointestinal, and vaginal infections with fungi, protozoa, and certain bacteria. In animals, it causes central nervous system damage and is not administered parenterally. It is also used as antiseptic, fungistat, or deodorant.
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Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 0.20 | g | V |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | D08AH02 | DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Quinoline derivatives |
| ATC | G01AC03 | GENITO URINARY SYSTEM AND SEX HORMONES GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS Quinoline derivatives |
| ATC | P01AA04 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ANTIPROTOZOALS AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES Hydroxyquinoline derivatives |
| ATC | R02AA11 | RESPIRATORY SYSTEM THROAT PREPARATIONS THROAT PREPARATIONS Antiseptics |
| FDA CS | M0000728 | Allergens |
| MeSH PA | D000890 | Anti-Infective Agents |
| FDA PE | N0000175629 | Increased Histamine Release |
| FDA PE | N0000184306 | Cell-mediated Immunity |
| FDA EPC | N0000185508 | Standardized Chemical Allergen |
| CHEBI has role | CHEBI:35820 | antiprotozoal drugs |
| CHEBI has role | CHEBI:36047 | antibacterial drugs |
| CHEBI has role | CHEBI:48218 | antiseptics |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 7.59 | acidic |
| pKa2 | 3.04 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Botulinum neurotoxin type A | Enzyme | IC50 | 5 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| N0000166918 | NUI |
| D07208 | KEGG_DRUG |
| C0008292 | UMLSCUI |
| CHEBI:74500 | CHEBI |
| CHEMBL224325 | ChEMBL_ID |
| DB13306 | DRUGBANK_ID |
| D002750 | MESH_DESCRIPTOR_UI |
| 6301 | PUBCHEM_CID |
| 215 | INN_ID |
| D6VHC87LLS | UNII |
| 2407 | RXNORM |
| 002899 | NDDF |
| 255863008 | SNOMEDCT_US |
| 411197006 | SNOMEDCT_US |
Pharmaceutical products:
None