chloroxylenol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3094 88-04-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • chloroxylenol sodium
  • chloroxylenol
  • benzytol
  • parametaxylenol
a antiseptic halogenated phenol, non-toxic, non-corrosive, non-staining with high phenol coefficient, it may be applied directly to a wound and shows no chemical reactivity toward blood
  • Molecular weight: 156.61
  • Formula: C8H9ClO
  • CLOGP: 3.48
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 1
  • TPSA: 20.23
  • ALOGS: -2.26
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Completed suicide 5748.79 29.73 1952 13797 129937 50459438
Toxicity to various agents 3448.64 29.73 1541 14208 210958 50378417
Drug abuse 1665.46 29.73 643 15106 59203 50530172
Intentional overdose 1186.37 29.73 511 15238 61993 50527382
Cardio-respiratory arrest 1160.39 29.73 482 15267 53410 50535965
Overdose 866.52 29.73 478 15271 99249 50490126
Suicide attempt 701.19 29.73 335 15414 51397 50537978
Alcohol interaction 493.79 29.73 118 15631 2026 50587349
Suspected suicide 425.47 29.73 127 15622 5230 50584145
Intentional product misuse 329.38 29.73 196 15553 46538 50542837
Respiratory arrest 327.62 29.73 168 15581 29841 50559534
Cardiac arrest 287.56 29.73 225 15524 83426 50505949
Alcohol poisoning 263.85 29.73 69 15680 1731 50587644
Death 241.20 29.73 391 15358 324988 50264387
Alcohol use 233.42 29.73 64 15685 1931 50587444
Coma 208.38 29.73 159 15590 56720 50532655
Drug ineffective 188.44 29.73 19 15730 819314 49770061
Somnolence 186.48 29.73 235 15514 154750 50434625
Alcohol abuse 185.92 29.73 53 15696 1848 50587527
Exposure to toxic agent 144.13 29.73 51 15698 3607 50585768
Loss of consciousness 110.90 29.73 149 15600 104204 50485171
Poisoning deliberate 106.10 29.73 51 15698 7861 50581514
Diarrhoea 105.23 29.73 27 15722 588449 50000926
Pain 104.59 29.73 26 15723 578877 50010498
Mydriasis 97.42 29.73 53 15696 10574 50578801
Agitation 94.53 29.73 99 15650 53285 50536090
Blood alcohol increased 93.07 29.73 24 15725 568 50588807
Alcoholism 89.04 29.73 29 15720 1591 50587784
Intentional self-injury 87.60 29.73 66 15683 23046 50566329
Arthralgia 86.69 29.73 16 15733 438686 50150689
Postmortem blood drug level abnormal 83.93 29.73 20 15729 338 50589037
Substance abuse 82.02 29.73 35 15714 4089 50585286
Fatigue 81.72 29.73 61 15688 707540 49881835
Rash 80.17 29.73 19 15730 437452 50151923
Poisoning 69.35 29.73 45 15704 12384 50576991
Dyspnoea 68.73 29.73 43 15706 547565 50041810
Drug use disorder 67.54 29.73 28 15721 3044 50586331
Drug dependence 67.38 29.73 53 15696 19706 50569669
Myocarditis 65.61 29.73 37 15712 7910 50581465
Aggression 64.28 29.73 53 15696 21063 50568312
Seizure 63.95 29.73 124 15625 117750 50471625
Suicidal ideation 63.26 29.73 82 15667 55303 50534072
Liver injury 62.76 29.73 56 15693 24750 50564625
Pruritus 61.25 29.73 8 15741 283560 50305815
Drug withdrawal syndrome 60.26 29.73 55 15694 25026 50564349
Pneumonia 59.15 29.73 22 15727 378379 50210996
Drug interaction 58.64 29.73 165 15584 199456 50389919
Condition aggravated 58.24 29.73 11 15738 297047 50292328
Headache 57.90 29.73 44 15705 506491 50082884
Alopecia 57.80 29.73 5 15744 245042 50344333
Victim of sexual abuse 57.64 29.73 16 15733 505 50588870
Depressed level of consciousness 56.36 29.73 75 15674 51878 50537497
Pain in extremity 55.90 29.73 9 15740 272856 50316519
Abdominal discomfort 53.89 29.73 5 15744 231636 50357739
Swelling 50.52 29.73 3 15746 200869 50388506
Drug intolerance 50.25 29.73 5 15744 219099 50370276
Off label use 49.52 29.73 45 15704 474381 50114994
Peripheral swelling 49.11 29.73 4 15745 205932 50383443
Pyrexia 47.41 29.73 30 15719 380173 50209202
Hypersensitivity 46.61 29.73 6 15743 215155 50374220
Tachycardia 45.84 29.73 98 15651 99665 50489710
Sopor 44.67 29.73 42 15707 19837 50569538
Anaemia 44.16 29.73 12 15737 252444 50336931
Somnambulism 43.58 29.73 24 15725 4900 50584475
Back pain 43.42 29.73 8 15741 220022 50369353
Product dose omission issue 42.66 29.73 4 15745 183834 50405541
Metabolic acidosis 42.02 29.73 56 15693 38769 50550606
Asphyxia 41.40 29.73 24 15725 5403 50583972
Chemical submission 41.37 29.73 10 15739 180 50589195
Nausea 40.57 29.73 101 15648 705297 49884078
Electrocardiogram QT prolonged 40.36 29.73 64 15685 51822 50537553
Nasopharyngitis 40.32 29.73 6 15743 192921 50396454
Cough 39.41 29.73 13 15736 241251 50348124
Sinusitis 38.82 29.73 4 15745 170554 50418821
Asthenia 38.62 29.73 26 15723 319016 50270359
Drug hypersensitivity 36.87 29.73 16 15733 250994 50338381
Urinary tract infection 36.71 29.73 12 15737 224008 50365367
Electrocardiogram QRS complex prolonged 36.49 29.73 22 15727 5322 50584053
Amnesia 35.48 29.73 54 15695 42206 50547169
Protein C increased 35.04 29.73 8 15741 111 50589264
Homicide 34.71 29.73 10 15739 362 50589013
Ventricular tachycardia 32.84 29.73 32 15717 15789 50573586
Weight increased 32.75 29.73 11 15738 201880 50387495
Infection 32.62 29.73 7 15742 172947 50416428
Abnormal behaviour 32.19 29.73 35 15714 19623 50569752
Substance dependence 30.76 29.73 8 15741 196 50589179
Constipation 30.32 29.73 10 15739 185698 50403677
Neutropenia 30.00 29.73 5 15744 147960 50441415
Sinus tachycardia 29.82 29.73 35 15714 21319 50568056

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug abuse 4315.61 28.12 1686 17424 78197 29477220
Completed suicide 3689.59 28.12 1561 17549 88685 29466732
Toxicity to various agents 3293.29 28.12 1768 17342 171893 29383524
Intentional overdose 821.47 28.12 429 18681 38099 29517318
Cardio-respiratory arrest 780.43 28.12 455 18655 50146 29505271
Overdose 626.98 28.12 471 18639 79348 29476069
Alcohol abuse 552.24 28.12 175 18935 4158 29551259
Alcohol interaction 515.81 28.12 149 18961 2554 29552863
Suicide attempt 499.48 28.12 297 18813 33813 29521604
Intentional product misuse 492.48 28.12 296 18814 34365 29521052
Suspected suicide 373.88 28.12 128 18982 3892 29551525
Substance abuse 295.17 28.12 124 18986 6663 29548754
Alcohol poisoning 285.83 28.12 98 19012 2991 29552426
Drug dependence 281.75 28.12 173 18937 20808 29534609
Aggression 189.83 28.12 168 18942 35373 29520044
Coma 184.35 28.12 173 18937 39277 29516140
Respiratory arrest 183.42 28.12 144 18966 25689 29529728
Alcohol use 176.65 28.12 69 19041 3063 29552354
Respiratory depression 162.55 28.12 104 19006 13419 29541998
Poisoning deliberate 151.45 28.12 74 19036 5657 29549760
Exposure to toxic agent 139.14 28.12 55 19055 2520 29552897
Asphyxia 132.62 28.12 66 19044 5249 29550168
Intentional product use issue 122.43 28.12 144 18966 42354 29513063
Drug ineffective 121.39 28.12 42 19068 363128 29192289
Diarrhoea 121.01 28.12 33 19077 332665 29222752
Incorrect route of product administration 114.98 28.12 77 19033 10724 29544693
Cardiac arrest 114.24 28.12 201 18909 85390 29470027
Pneumonia 112.28 28.12 34 19076 320138 29235279
Blood alcohol increased 107.68 28.12 33 19077 697 29554720
Anaemia 102.80 28.12 7 19103 200944 29354473
Pyrexia 96.43 28.12 33 19077 287589 29267828
Poisoning 89.34 28.12 64 19046 9929 29545488
Suicidal ideation 84.36 28.12 108 19002 34608 29520809
Rash 83.08 28.12 12 19098 189807 29365610
Drug withdrawal syndrome 82.24 28.12 78 19032 17906 29537511
Fatigue 82.07 28.12 52 19058 316769 29238648
Intentional self-injury 78.89 28.12 65 19045 12396 29543021
Dyspnoea 78.81 28.12 58 19052 326674 29228743
Alcohol withdrawal syndrome 76.54 28.12 30 19080 1343 29554074
Sopor 75.49 28.12 60 19050 10874 29544543
Death 68.46 28.12 415 18695 341669 29213748
Neutropenia 66.10 28.12 5 19105 131706 29423711
Cough 63.06 28.12 5 19105 126722 29428695
Drug interaction 62.86 28.12 273 18837 197112 29358305
Drug use disorder 61.15 28.12 34 19076 3388 29552029
Miosis 59.72 28.12 46 19064 7963 29547454
Sepsis 57.98 28.12 11 19099 142671 29412746
Agitation 57.67 28.12 112 18998 51192 29504225
Off label use 56.44 28.12 67 19043 300733 29254684
Medication error 56.31 28.12 69 19041 21142 29534275
Road traffic accident 55.52 28.12 59 19051 15502 29539915
Arthralgia 54.17 28.12 12 19098 139605 29415812
Drug screen positive 52.63 28.12 32 19078 3769 29551648
Accidental death 51.94 28.12 26 19084 2092 29553325
Alcoholism 51.86 28.12 28 19082 2633 29552784
Alcohol intolerance 50.47 28.12 16 19094 379 29555038
Tachycardia 47.78 28.12 128 18982 72282 29483135
Mydriasis 47.68 28.12 36 19074 6049 29549368
Platelet count decreased 47.20 28.12 6 19104 104666 29450751
Hepatic fibrosis 46.63 28.12 28 19082 3224 29552193
Pain in extremity 45.96 28.12 8 19102 110425 29444992
Constipation 45.94 28.12 9 19101 114151 29441266
Pain 45.84 28.12 27 19083 171405 29384012
Ex-drug abuser 45.61 28.12 12 19098 142 29555275
Pruritus 45.40 28.12 10 19100 116839 29438578
Amnesia 45.14 28.12 64 19046 22579 29532838
Asthenia 44.69 28.12 44 19066 215206 29340211
Depressed level of consciousness 43.15 28.12 82 19028 36860 29518557
Somnolence 43.02 28.12 146 18964 93809 29461608
Haemoglobin decreased 42.66 28.12 9 19101 108366 29447051
Pancytopenia 42.15 28.12 3 19107 83165 29472252
Condition aggravated 42.08 28.12 21 19089 146274 29409143
Product dose omission issue 40.06 28.12 7 19103 96376 29459041
Nausea 39.32 28.12 80 19030 289175 29266242
Loss of consciousness 39.24 28.12 121 18989 73935 29481482
Back pain 39.23 28.12 9 19101 102275 29453142
Decreased appetite 38.69 28.12 23 19087 145319 29410098
Impaired driving ability 38.51 28.12 22 19088 2309 29553108
Withdrawal syndrome 38.01 28.12 41 19069 10951 29544466
Dysarthria 37.83 28.12 70 19040 30841 29524576
Drug abuser 37.66 28.12 26 19084 3801 29551616
Pulmonary oedema 36.04 28.12 83 19027 42652 29512765
General physical health deterioration 34 28.12 12 19098 102845 29452572
Homicide 33.90 28.12 15 19095 913 29554504
Weight decreased 33.47 28.12 29 19081 150876 29404541
Metabolic acidosis 32.70 28.12 74 19036 37588 29517829
Oedema peripheral 32.69 28.12 13 19097 103544 29451873
Foetal alcohol syndrome 32.18 28.12 9 19101 136 29555281
Cerebrovascular accident 31.06 28.12 6 19104 76905 29478512
Cardiac failure congestive 30.87 28.12 6 19104 76575 29478842
Peripheral swelling 30.37 28.12 3 19107 63736 29491681
Neuropathy peripheral 29.85 28.12 5 19105 71022 29484395
Myocardial fibrosis 28.83 28.12 14 19096 1054 29554363
Physical assault 28.64 28.12 14 19096 1070 29554347
Thrombocytopenia 28.58 28.12 27 19083 134796 29420621
Urinary tract infection 28.48 28.12 6 19104 72348 29483069
Cardiac failure 28.43 28.12 8 19102 79279 29476138

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Completed suicide 8857.28 26.56 3469 27632 220945 64246686
Toxicity to various agents 6476.85 26.56 3218 27883 360295 64107336
Drug abuse 5806.63 26.56 2222 28879 130152 64337479
Cardio-respiratory arrest 1897.43 26.56 930 30171 97463 64370168
Intentional overdose 1593.35 26.56 803 30298 89141 64378490
Overdose 1208.63 26.56 821 30280 158745 64308886
Alcohol interaction 836.60 26.56 227 30874 4174 64463457
Intentional product misuse 777.52 26.56 465 30636 71830 64395801
Suicide attempt 748.77 26.56 451 30650 70556 64397075
Suspected suicide 721.35 26.56 236 30865 8418 64459213
Alcohol abuse 557.09 26.56 169 30932 4683 64462948
Respiratory arrest 480.61 26.56 306 30795 52679 64414952
Alcohol poisoning 440.92 26.56 137 30964 4118 64463513
Cardiac arrest 364.75 26.56 409 30692 153655 64313976
Death 355.22 26.56 742 30359 481963 63985668
Coma 343.26 26.56 306 30795 87309 64380322
Alcohol use 341.43 26.56 115 30986 4487 64463144
Substance abuse 312.55 26.56 130 30971 9162 64458469
Drug dependence 308.39 26.56 195 30906 33117 64434514
Exposure to toxic agent 272.51 26.56 105 30996 6054 64461577
Drug ineffective 259 26.56 47 31054 840200 63627431
Poisoning deliberate 239.70 26.56 121 30980 13337 64454294
Diarrhoea 210.82 26.56 46 31055 722658 63744973
Aggression 191.92 26.56 167 30934 46065 64421566
Blood alcohol increased 174.32 26.56 50 31051 1132 64466499
Fatigue 154.33 26.56 85 31016 748645 63718986
Pain 151.81 26.56 40 31061 553471 63914160
Pneumonia 145.04 26.56 45 31056 559531 63908100
Dyspnoea 143.20 26.56 85 31016 718589 63749042
Arthralgia 141.88 26.56 22 31079 442238 64025393
Respiratory depression 140.47 26.56 105 30996 23338 64444293
Rash 140.07 26.56 26 31075 458523 64009108
Incorrect route of product administration 138.82 26.56 104 30997 23194 64444437
Somnolence 138.42 26.56 304 30797 203341 64264290
Asphyxia 136.06 26.56 74 31027 9492 64458139
Poisoning 133.34 26.56 99 31002 21780 64445851
Intentional self-injury 132.94 26.56 111 30990 28933 64438698
Anaemia 130.56 26.56 15 31086 378665 64088966
Pyrexia 129.34 26.56 54 31047 558590 63909041
Off label use 128.60 26.56 73 31028 632733 63834898
Agitation 125.17 26.56 182 30919 88185 64379446
Intentional product use issue 124.46 26.56 189 30912 95175 64372456
Drug use disorder 115.36 26.56 57 31044 5997 64461634
Mydriasis 110.99 26.56 77 31024 15235 64452396
Nausea 104.52 26.56 136 30965 785664 63681967
Pain in extremity 104.44 26.56 12 31089 303073 64164558
Condition aggravated 101.80 26.56 27 31074 372399 64095232
Pruritus 101.33 26.56 15 31086 312385 64155246
Loss of consciousness 99.04 26.56 220 30881 148145 64319486
Cough 90.32 26.56 18 31083 302130 64165501
Postmortem blood drug level abnormal 89.32 26.56 26 31075 621 64467010
Headache 88.96 26.56 75 31026 529392 63938239
Suicidal ideation 86.94 26.56 132 30969 66410 64401221
Sopor 86.28 26.56 88 31013 29573 64438058
Alcoholism 86.07 26.56 39 31062 3378 64464253
Depressed level of consciousness 83.87 26.56 145 30956 81291 64386340
Back pain 83.48 26.56 11 31090 250160 64217471
Drug interaction 82.34 26.56 369 30732 361714 64105917
Neutropenia 81.25 26.56 10 31091 239614 64228017
Accidental death 79.79 26.56 38 31063 3687 64463944
Miosis 78.52 26.56 59 31042 13207 64454424
Peripheral swelling 78.07 26.56 6 31095 209147 64258484
Alcohol withdrawal syndrome 77.12 26.56 30 31071 1773 64465858
Metabolic acidosis 72.61 26.56 126 30975 70832 64396799
Tachycardia 72.31 26.56 196 30905 149383 64318248
Asthenia 71.39 26.56 61 31040 427983 64039648
Drug intolerance 71.28 26.56 5 31096 187987 64279644
Constipation 69.91 26.56 13 31088 229324 64238307
Nasopharyngitis 69.45 26.56 7 31094 196066 64271565
Urinary tract infection 68.76 26.56 14 31087 231582 64236049
Pulmonary oedema 64.52 26.56 127 30974 78547 64389084
Drug withdrawal syndrome 63.65 26.56 77 31024 31214 64436417
Sepsis 62.30 26.56 17 31084 230324 64237307
Product dose omission issue 61.62 26.56 10 31091 194737 64272894
Alopecia 61.13 26.56 5 31096 165685 64301946
Malaise 60.70 26.56 61 31040 396186 64071445
Infection 59.61 26.56 9 31092 184871 64282760
Haemoglobin decreased 59.56 26.56 11 31090 195052 64272579
Weight decreased 59.25 26.56 32 31069 285707 64181924
Swelling 58.65 26.56 5 31096 160213 64307418
Hypersensitivity 58.05 26.56 12 31089 196440 64271191
White blood cell count decreased 57.58 26.56 5 31096 157832 64309799
Weight increased 57.22 26.56 16 31085 213332 64254299
Drug abuser 56.21 26.56 35 31066 5773 64461858
Decreased appetite 56.16 26.56 33 31068 281256 64186375
Homicide 55.86 26.56 21 31080 1130 64466501
Shock 54.44 26.56 79 31022 38161 64429470
Abdominal discomfort 54.15 26.56 11 31090 182311 64285320
Drug screen positive 54.13 26.56 34 31067 5695 64461936
Sinusitis 52.21 26.56 5 31096 145923 64321708
Drug hypersensitivity 51.72 26.56 25 31076 237790 64229841
Medication error 51.46 26.56 89 31012 49877 64417754
Pancytopenia 51.04 26.56 5 31096 143304 64324327
Platelet count decreased 50.05 26.56 10 31091 167701 64299930
Opiates positive 49.53 26.56 18 31083 880 64466751
Road traffic accident 48.93 26.56 67 31034 30678 64436953
General physical health deterioration 46.77 26.56 20 31081 204405 64263226
Electrocardiogram QRS complex prolonged 45.78 26.56 37 31064 9207 64458424
Liver injury 44.31 26.56 63 31038 29869 64437762
Product administration error 43.63 26.56 60 31041 27583 64440048
Urticaria 43.50 26.56 9 31092 147308 64320323
Hepatic fibrosis 42.78 26.56 29 31072 5523 64462108
Amnesia 42.10 26.56 80 31021 48189 64419442
Cerebrovascular accident 41.47 26.56 8 31093 137575 64330056
Stomatitis 41.28 26.56 3 31098 109602 64358029
Cardiac failure congestive 40.64 26.56 7 31094 130573 64337058
Musculoskeletal stiffness 39.70 26.56 6 31095 123200 64344431
Abdominal pain 39.36 26.56 56 31045 312319 64155312
Blood ethanol increased 39.34 26.56 14 31087 644 64466987
Muscular weakness 39.25 26.56 7 31094 127331 64340300
Accidental overdose 38.85 26.56 63 31038 33494 64434137
Therapeutic product effect decreased 38.62 26.56 5 31096 115346 64352285
Therapeutic product effect incomplete 38.50 26.56 3 31098 103479 64364152
Sinus tachycardia 38.04 26.56 61 31040 32127 64435504
Unresponsive to stimuli 37.31 26.56 78 31023 50315 64417316
Fall 37.29 26.56 92 31009 416734 64050897
Thrombocytopenia 37.11 26.56 32 31069 223769 64243862
Dizziness 36.90 26.56 97 31004 430066 64037565
Septic shock 36.71 26.56 4 31097 105433 64362198
Dehydration 35.93 26.56 31 31070 216732 64250899
Blood ethanol 35.43 26.56 9 31092 126 64467505
Electrocardiogram QT prolonged 35.29 26.56 101 31000 79347 64388284
Somnambulism 35.26 26.56 25 31076 5116 64462515
Chemical submission 35.22 26.56 10 31091 218 64467413
Dysarthria 35.06 26.56 84 31017 59322 64408309
Oedema peripheral 34.96 26.56 30 31071 210287 64257344
Asthma 34.76 26.56 3 31098 95222 64372409
Abnormal behaviour 34.76 26.56 60 31041 33562 64434069
Amphetamines positive 34.67 26.56 10 31091 231 64467400
Injection site pain 34.61 26.56 6 31095 111402 64356229
Withdrawal syndrome 34.11 26.56 49 31052 23443 64444188
Toxicologic test abnormal 34.11 26.56 15 31086 1210 64466421
Euphoric mood 33.96 26.56 27 31074 6564 64461067
Alcohol intolerance 33.73 26.56 11 31090 387 64467244
Postmortem blood drug level 33.69 26.56 10 31091 256 64467375
Victim of sexual abuse 33.49 26.56 11 31090 396 64467235
Myocardial fibrosis 33.48 26.56 16 31085 1564 64466067
Neuropathy peripheral 33.05 26.56 8 31093 117517 64350114
Rhabdomyolysis 32.71 26.56 108 30993 91618 64376013
Abdominal distension 32.52 26.56 4 31097 95990 64371641
Influenza 32.52 26.56 6 31095 106525 64361106
Erythema 31.93 26.56 26 31075 187044 64280587
Cellulitis 31.49 26.56 4 31097 93653 64373978
Substance dependence 31.49 26.56 11 31090 479 64467152
Bronchitis 31.37 26.56 7 31094 108736 64358895
Brain oedema 30.54 26.56 45 31056 22030 64445601
Acute hepatic failure 30.20 26.56 49 31052 26063 64441568
Respiratory acidosis 30.04 26.56 30 31071 9825 64457806
Chest pain 30.01 26.56 42 31059 235938 64231693
Oropharyngeal pain 29.39 26.56 4 31097 88863 64378768
Seizure 28.49 26.56 157 30944 166735 64300896
Blister 28.37 26.56 3 31098 80964 64386667
Discomfort 28.33 26.56 3 31098 80875 64386756
Impaired driving ability 28.21 26.56 21 31080 4633 64462998
Deep vein thrombosis 27.97 26.56 8 31093 105174 64362457
Physical assault 27.81 26.56 14 31087 1532 64466099
Restlessness 27.63 26.56 60 31041 39725 64427906
Protein C increased 27.17 26.56 7 31094 104 64467527
Dysphagia 26.83 26.56 9 31092 106803 64360828
Renal impairment 26.69 26.56 16 31085 135001 64332630

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D08AE05 DERMATOLOGICALS
ANTISEPTICS AND DISINFECTANTS
ANTISEPTICS AND DISINFECTANTS
Phenol and derivatives
MeSH PA D000871 Anthelmintics
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
MeSH PA D000977 Antiparasitic Agents
MeSH PA D000980 Antiplatyhelmintic Agents
MeSH PA D004202 Disinfectants
MeSH PA D012556 Schistosomicides
CHEBI has role CHEBI:33904 molluscicides
CHEBI has role CHEBI:48218 antiseptics
CHEBI has role CHEBI:48219 disinfectants

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Antiseptic preparation indication 261276004




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.85 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
5-hydroxytryptamine receptor 2B GPCR Ki 5.93 DRUG MATRIX
Amine oxidase [flavin-containing] A Enzyme IC50 5.74 DRUG MATRIX

External reference:

IDSource
4019458 VUID
N0000147580 NUI
D03473 KEGG_DRUG
4018914 VANDF
4019458 VANDF
C0055463 UMLSCUI
CHEBI:34393 CHEBI
CHEMBL398440 ChEMBL_ID
DB11121 DRUGBANK_ID
2723 PUBCHEM_CID
492 INN_ID
C007027 MESH_SUPPLEMENTAL_RECORD_UI
0F32U78V2Q UNII
20877 RXNORM
4423 MMSL
72857 MMSL
003140 NDDF
003202 NDDF
126151007 SNOMEDCT_US
398713003 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Antibacterial Hand HUMAN OTC DRUG LABEL 1 0404-4438 SOAP 6.10 g TOPICAL OTC monograph not final 11 sections
Antibacterial HUMAN OTC DRUG LABEL 1 0404-4441 LIQUID 6.05 g TOPICAL OTC monograph not final 11 sections
Antimicrobial Hand Wash HUMAN OTC DRUG LABEL 1 0404-5987 SOAP 6 mg TOPICAL OTC monograph not final 11 sections
Antimicrobial Hand Wash HUMAN OTC DRUG LABEL 1 0404-5990 SOAP 6 mg TOPICAL OTC monograph not final 11 sections
Blistex Foille Medicated First Aid HUMAN OTC DRUG LABEL 2 10157-9302 OINTMENT 0.10 g TOPICAL OTC MONOGRAPH NOT FINAL 13 sections
PC511 ANTIMICROBIAL HUMAN OTC DRUG LABEL 1 10685-511 SOAP 3 g TOPICAL OTC monograph not final 9 sections
PC529 ULTREX HUMAN OTC DRUG LABEL 1 10685-529 SOAP 2.50 g TOPICAL OTC monograph not final 9 sections
PC537 E-2 BRUTE HUMAN OTC DRUG LABEL 1 10685-537 SOAP 25 g TOPICAL OTC monograph not final 9 sections
PC557 PALPON HUMAN OTC DRUG LABEL 1 10685-557 SOAP 2.50 g TOPICAL OTC monograph not final 9 sections
NAMICO ANTISEPTIC HAND CLEANER 557 HUMAN OTC DRUG LABEL 1 10685-978 SOAP 2.50 g TOPICAL OTC monograph not final 9 sections
Derma CIDOL 2000 HUMAN OTC DRUG LABEL 1 10802-8081 LIQUID 0.50 g TOPICAL OTC monograph not final 8 sections
Kindest Kare Hand Antimicrobial Handwash HUMAN OTC DRUG LABEL 1 11084-036 SOAP 1 g TOPICAL OTC MONOGRAPH NOT FINAL 12 sections
PureBac Foam Wash HUMAN OTC DRUG LABEL 1 11084-131 LIQUID 0.50 mL TOPICAL OTC monograph not final 9 sections
Refresh PureBac Foam HUMAN OTC DRUG LABEL 1 11084-160 LIQUID 5 g TOPICAL OTC monograph not final 10 sections
Acute-Kare Healthcare Personnel Handwash HUMAN OTC DRUG LABEL 1 11084-800 SOAP 1 g TOPICAL OTC monograph not final 12 sections
Chloroxylenol HUMAN OTC DRUG LABEL 1 11344-562 LIQUID 3.09 g TOPICAL OTC monograph not final 12 sections
chloroxylenol HUMAN OTC DRUG LABEL 1 11344-710 LIQUID 3.09 mg TOPICAL OTC monograph not final 11 sections
chloroxylenol HUMAN OTC DRUG LABEL 1 11344-710 LIQUID 3.09 mg TOPICAL OTC monograph not final 11 sections
antibacterial HUMAN OTC DRUG LABEL 1 11344-713 LIQUID 3 mg TOPICAL OTC monograph not final 11 sections
FoamFresh Antibacterial Hand Wash HUMAN OTC DRUG LABEL 1 11429-1005 LIQUID 2.50 mg TOPICAL OTC monograph not final 11 sections
FoamFresh Antibacterial Hand Wash HUMAN OTC DRUG LABEL 1 11429-1005 LIQUID 2.50 mg TOPICAL OTC monograph not final 11 sections
Lemon Drop Gentle Antiseptic HUMAN OTC DRUG LABEL 1 11429-1006 LIQUID 3 mg TOPICAL OTC monograph not final 11 sections
Derma 1 Healthcare Hand Wash HUMAN OTC DRUG LABEL 1 11429-1007 LIQUID 4 mg TOPICAL OTC monograph not final 11 sections
FoamFresh Healthcare Hand Wash HUMAN OTC DRUG LABEL 1 11429-1008 LIQUID 7.50 mg TOPICAL OTC monograph not final 11 sections
Pink Antibacterial HUMAN OTC DRUG LABEL 1 11429-1009 LIQUID 3 mg TOPICAL OTC monograph not final 11 sections
FoamFresh Dye Free Antibacterial Hand Wash HUMAN OTC DRUG LABEL 1 11429-1010 SOLUTION 2.50 mg TOPICAL OTC monograph not final 11 sections
FoamFresh E-2 Sanitizer Cleanser with PCMX HUMAN OTC DRUG LABEL 1 11429-1011 LIQUID 5 mg TOPICAL OTC monograph not final 10 sections
Antiseptic Hand HUMAN OTC DRUG LABEL 1 16496-544 SOAP 3 mg TOPICAL OTC monograph not final 10 sections
BD E-Z SCRUB HUMAN OTC DRUG LABEL 1 17271-116 SOLUTION 30 mg TOPICAL OTC monograph not final 14 sections
BD E-Z Scrub HUMAN OTC DRUG LABEL 1 17271-502 SOLUTION 30 mg TOPICAL OTC monograph not final 14 sections