chloroxylenol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	3094	88-04-0

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: chloroxylenol sodium chloroxylenol benzytol parametaxylenol	a antiseptic halogenated phenol, non-toxic, non-corrosive, non-staining with high phenol coefficient, it may be applied directly to a wound and shows no chemical reactivity toward blood Molecular weight: 156.61 Formula: C8H9ClO CLOGP: 3.48 LIPINSKI: 0 HAC: 1 HDO: 1 TPSA: 20.23 ALOGS: -2.26 ROTB: 0

Molecule

Description

Molfile Inchi Smiles

Synonyms:

chloroxylenol sodium
chloroxylenol
benzytol
parametaxylenol

a antiseptic halogenated phenol, non-toxic, non-corrosive, non-staining with high phenol coefficient, it may be applied directly to a wound and shows no chemical reactivity toward blood

Molecular weight: 156.61
Formula: C8H9ClO
CLOGP: 3.48
LIPINSKI: 0
HAC: 1
HDO: 1
TPSA: 20.23
ALOGS: -2.26
ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Completed suicide	5748.79	29.73	1952	13797	129937	50459438
Toxicity to various agents	3448.64	29.73	1541	14208	210958	50378417
Drug abuse	1665.46	29.73	643	15106	59203	50530172
Intentional overdose	1186.37	29.73	511	15238	61993	50527382
Cardio-respiratory arrest	1160.39	29.73	482	15267	53410	50535965
Overdose	866.52	29.73	478	15271	99249	50490126
Suicide attempt	701.19	29.73	335	15414	51397	50537978
Alcohol interaction	493.79	29.73	118	15631	2026	50587349
Suspected suicide	425.47	29.73	127	15622	5230	50584145
Intentional product misuse	329.38	29.73	196	15553	46538	50542837
Respiratory arrest	327.62	29.73	168	15581	29841	50559534
Cardiac arrest	287.56	29.73	225	15524	83426	50505949
Alcohol poisoning	263.85	29.73	69	15680	1731	50587644
Death	241.20	29.73	391	15358	324988	50264387
Alcohol use	233.42	29.73	64	15685	1931	50587444
Coma	208.38	29.73	159	15590	56720	50532655
Drug ineffective	188.44	29.73	19	15730	819314	49770061
Somnolence	186.48	29.73	235	15514	154750	50434625
Alcohol abuse	185.92	29.73	53	15696	1848	50587527
Exposure to toxic agent	144.13	29.73	51	15698	3607	50585768
Loss of consciousness	110.90	29.73	149	15600	104204	50485171
Poisoning deliberate	106.10	29.73	51	15698	7861	50581514
Diarrhoea	105.23	29.73	27	15722	588449	50000926
Pain	104.59	29.73	26	15723	578877	50010498
Mydriasis	97.42	29.73	53	15696	10574	50578801
Agitation	94.53	29.73	99	15650	53285	50536090
Blood alcohol increased	93.07	29.73	24	15725	568	50588807
Alcoholism	89.04	29.73	29	15720	1591	50587784
Intentional self-injury	87.60	29.73	66	15683	23046	50566329
Arthralgia	86.69	29.73	16	15733	438686	50150689
Postmortem blood drug level abnormal	83.93	29.73	20	15729	338	50589037
Substance abuse	82.02	29.73	35	15714	4089	50585286
Fatigue	81.72	29.73	61	15688	707540	49881835
Rash	80.17	29.73	19	15730	437452	50151923
Poisoning	69.35	29.73	45	15704	12384	50576991
Dyspnoea	68.73	29.73	43	15706	547565	50041810
Drug use disorder	67.54	29.73	28	15721	3044	50586331
Drug dependence	67.38	29.73	53	15696	19706	50569669
Myocarditis	65.61	29.73	37	15712	7910	50581465
Aggression	64.28	29.73	53	15696	21063	50568312
Seizure	63.95	29.73	124	15625	117750	50471625
Suicidal ideation	63.26	29.73	82	15667	55303	50534072
Liver injury	62.76	29.73	56	15693	24750	50564625
Pruritus	61.25	29.73	8	15741	283560	50305815
Drug withdrawal syndrome	60.26	29.73	55	15694	25026	50564349
Pneumonia	59.15	29.73	22	15727	378379	50210996
Drug interaction	58.64	29.73	165	15584	199456	50389919
Condition aggravated	58.24	29.73	11	15738	297047	50292328
Headache	57.90	29.73	44	15705	506491	50082884
Alopecia	57.80	29.73	5	15744	245042	50344333
Victim of sexual abuse	57.64	29.73	16	15733	505	50588870
Depressed level of consciousness	56.36	29.73	75	15674	51878	50537497
Pain in extremity	55.90	29.73	9	15740	272856	50316519
Abdominal discomfort	53.89	29.73	5	15744	231636	50357739
Swelling	50.52	29.73	3	15746	200869	50388506
Drug intolerance	50.25	29.73	5	15744	219099	50370276
Off label use	49.52	29.73	45	15704	474381	50114994
Peripheral swelling	49.11	29.73	4	15745	205932	50383443
Pyrexia	47.41	29.73	30	15719	380173	50209202
Hypersensitivity	46.61	29.73	6	15743	215155	50374220
Tachycardia	45.84	29.73	98	15651	99665	50489710
Sopor	44.67	29.73	42	15707	19837	50569538
Anaemia	44.16	29.73	12	15737	252444	50336931
Somnambulism	43.58	29.73	24	15725	4900	50584475
Back pain	43.42	29.73	8	15741	220022	50369353
Product dose omission issue	42.66	29.73	4	15745	183834	50405541
Metabolic acidosis	42.02	29.73	56	15693	38769	50550606
Asphyxia	41.40	29.73	24	15725	5403	50583972
Chemical submission	41.37	29.73	10	15739	180	50589195
Nausea	40.57	29.73	101	15648	705297	49884078
Electrocardiogram QT prolonged	40.36	29.73	64	15685	51822	50537553
Nasopharyngitis	40.32	29.73	6	15743	192921	50396454
Cough	39.41	29.73	13	15736	241251	50348124
Sinusitis	38.82	29.73	4	15745	170554	50418821
Asthenia	38.62	29.73	26	15723	319016	50270359
Drug hypersensitivity	36.87	29.73	16	15733	250994	50338381
Urinary tract infection	36.71	29.73	12	15737	224008	50365367
Electrocardiogram QRS complex prolonged	36.49	29.73	22	15727	5322	50584053
Amnesia	35.48	29.73	54	15695	42206	50547169
Protein C increased	35.04	29.73	8	15741	111	50589264
Homicide	34.71	29.73	10	15739	362	50589013
Ventricular tachycardia	32.84	29.73	32	15717	15789	50573586
Weight increased	32.75	29.73	11	15738	201880	50387495
Infection	32.62	29.73	7	15742	172947	50416428
Abnormal behaviour	32.19	29.73	35	15714	19623	50569752
Substance dependence	30.76	29.73	8	15741	196	50589179
Constipation	30.32	29.73	10	15739	185698	50403677
Neutropenia	30.00	29.73	5	15744	147960	50441415
Sinus tachycardia	29.82	29.73	35	15714	21319	50568056

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Drug abuse	4315.61	28.12	1686	17424	78197	29477220
Completed suicide	3689.59	28.12	1561	17549	88685	29466732
Toxicity to various agents	3293.29	28.12	1768	17342	171893	29383524
Intentional overdose	821.47	28.12	429	18681	38099	29517318
Cardio-respiratory arrest	780.43	28.12	455	18655	50146	29505271
Overdose	626.98	28.12	471	18639	79348	29476069
Alcohol abuse	552.24	28.12	175	18935	4158	29551259
Alcohol interaction	515.81	28.12	149	18961	2554	29552863
Suicide attempt	499.48	28.12	297	18813	33813	29521604
Intentional product misuse	492.48	28.12	296	18814	34365	29521052
Suspected suicide	373.88	28.12	128	18982	3892	29551525
Substance abuse	295.17	28.12	124	18986	6663	29548754
Alcohol poisoning	285.83	28.12	98	19012	2991	29552426
Drug dependence	281.75	28.12	173	18937	20808	29534609
Aggression	189.83	28.12	168	18942	35373	29520044
Coma	184.35	28.12	173	18937	39277	29516140
Respiratory arrest	183.42	28.12	144	18966	25689	29529728
Alcohol use	176.65	28.12	69	19041	3063	29552354
Respiratory depression	162.55	28.12	104	19006	13419	29541998
Poisoning deliberate	151.45	28.12	74	19036	5657	29549760
Exposure to toxic agent	139.14	28.12	55	19055	2520	29552897
Asphyxia	132.62	28.12	66	19044	5249	29550168
Intentional product use issue	122.43	28.12	144	18966	42354	29513063
Drug ineffective	121.39	28.12	42	19068	363128	29192289
Diarrhoea	121.01	28.12	33	19077	332665	29222752
Incorrect route of product administration	114.98	28.12	77	19033	10724	29544693
Cardiac arrest	114.24	28.12	201	18909	85390	29470027
Pneumonia	112.28	28.12	34	19076	320138	29235279
Blood alcohol increased	107.68	28.12	33	19077	697	29554720
Anaemia	102.80	28.12	7	19103	200944	29354473
Pyrexia	96.43	28.12	33	19077	287589	29267828
Poisoning	89.34	28.12	64	19046	9929	29545488
Suicidal ideation	84.36	28.12	108	19002	34608	29520809
Rash	83.08	28.12	12	19098	189807	29365610
Drug withdrawal syndrome	82.24	28.12	78	19032	17906	29537511
Fatigue	82.07	28.12	52	19058	316769	29238648
Intentional self-injury	78.89	28.12	65	19045	12396	29543021
Dyspnoea	78.81	28.12	58	19052	326674	29228743
Alcohol withdrawal syndrome	76.54	28.12	30	19080	1343	29554074
Sopor	75.49	28.12	60	19050	10874	29544543
Death	68.46	28.12	415	18695	341669	29213748
Neutropenia	66.10	28.12	5	19105	131706	29423711
Cough	63.06	28.12	5	19105	126722	29428695
Drug interaction	62.86	28.12	273	18837	197112	29358305
Drug use disorder	61.15	28.12	34	19076	3388	29552029
Miosis	59.72	28.12	46	19064	7963	29547454
Sepsis	57.98	28.12	11	19099	142671	29412746
Agitation	57.67	28.12	112	18998	51192	29504225
Off label use	56.44	28.12	67	19043	300733	29254684
Medication error	56.31	28.12	69	19041	21142	29534275
Road traffic accident	55.52	28.12	59	19051	15502	29539915
Arthralgia	54.17	28.12	12	19098	139605	29415812
Drug screen positive	52.63	28.12	32	19078	3769	29551648
Accidental death	51.94	28.12	26	19084	2092	29553325
Alcoholism	51.86	28.12	28	19082	2633	29552784
Alcohol intolerance	50.47	28.12	16	19094	379	29555038
Tachycardia	47.78	28.12	128	18982	72282	29483135
Mydriasis	47.68	28.12	36	19074	6049	29549368
Platelet count decreased	47.20	28.12	6	19104	104666	29450751
Hepatic fibrosis	46.63	28.12	28	19082	3224	29552193
Pain in extremity	45.96	28.12	8	19102	110425	29444992
Constipation	45.94	28.12	9	19101	114151	29441266
Pain	45.84	28.12	27	19083	171405	29384012
Ex-drug abuser	45.61	28.12	12	19098	142	29555275
Pruritus	45.40	28.12	10	19100	116839	29438578
Amnesia	45.14	28.12	64	19046	22579	29532838
Asthenia	44.69	28.12	44	19066	215206	29340211
Depressed level of consciousness	43.15	28.12	82	19028	36860	29518557
Somnolence	43.02	28.12	146	18964	93809	29461608
Haemoglobin decreased	42.66	28.12	9	19101	108366	29447051
Pancytopenia	42.15	28.12	3	19107	83165	29472252
Condition aggravated	42.08	28.12	21	19089	146274	29409143
Product dose omission issue	40.06	28.12	7	19103	96376	29459041
Nausea	39.32	28.12	80	19030	289175	29266242
Loss of consciousness	39.24	28.12	121	18989	73935	29481482
Back pain	39.23	28.12	9	19101	102275	29453142
Decreased appetite	38.69	28.12	23	19087	145319	29410098
Impaired driving ability	38.51	28.12	22	19088	2309	29553108
Withdrawal syndrome	38.01	28.12	41	19069	10951	29544466
Dysarthria	37.83	28.12	70	19040	30841	29524576
Drug abuser	37.66	28.12	26	19084	3801	29551616
Pulmonary oedema	36.04	28.12	83	19027	42652	29512765
General physical health deterioration	34	28.12	12	19098	102845	29452572
Homicide	33.90	28.12	15	19095	913	29554504
Weight decreased	33.47	28.12	29	19081	150876	29404541
Metabolic acidosis	32.70	28.12	74	19036	37588	29517829
Oedema peripheral	32.69	28.12	13	19097	103544	29451873
Foetal alcohol syndrome	32.18	28.12	9	19101	136	29555281
Cerebrovascular accident	31.06	28.12	6	19104	76905	29478512
Cardiac failure congestive	30.87	28.12	6	19104	76575	29478842
Peripheral swelling	30.37	28.12	3	19107	63736	29491681
Neuropathy peripheral	29.85	28.12	5	19105	71022	29484395
Myocardial fibrosis	28.83	28.12	14	19096	1054	29554363
Physical assault	28.64	28.12	14	19096	1070	29554347
Thrombocytopenia	28.58	28.12	27	19083	134796	29420621
Urinary tract infection	28.48	28.12	6	19104	72348	29483069
Cardiac failure	28.43	28.12	8	19102	79279	29476138

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Completed suicide	8857.28	26.56	3469	27632	220945	64246686
Toxicity to various agents	6476.85	26.56	3218	27883	360295	64107336
Drug abuse	5806.63	26.56	2222	28879	130152	64337479
Cardio-respiratory arrest	1897.43	26.56	930	30171	97463	64370168
Intentional overdose	1593.35	26.56	803	30298	89141	64378490
Overdose	1208.63	26.56	821	30280	158745	64308886
Alcohol interaction	836.60	26.56	227	30874	4174	64463457
Intentional product misuse	777.52	26.56	465	30636	71830	64395801
Suicide attempt	748.77	26.56	451	30650	70556	64397075
Suspected suicide	721.35	26.56	236	30865	8418	64459213
Alcohol abuse	557.09	26.56	169	30932	4683	64462948
Respiratory arrest	480.61	26.56	306	30795	52679	64414952
Alcohol poisoning	440.92	26.56	137	30964	4118	64463513
Cardiac arrest	364.75	26.56	409	30692	153655	64313976
Death	355.22	26.56	742	30359	481963	63985668
Coma	343.26	26.56	306	30795	87309	64380322
Alcohol use	341.43	26.56	115	30986	4487	64463144
Substance abuse	312.55	26.56	130	30971	9162	64458469
Drug dependence	308.39	26.56	195	30906	33117	64434514
Exposure to toxic agent	272.51	26.56	105	30996	6054	64461577
Drug ineffective	259	26.56	47	31054	840200	63627431
Poisoning deliberate	239.70	26.56	121	30980	13337	64454294
Diarrhoea	210.82	26.56	46	31055	722658	63744973
Aggression	191.92	26.56	167	30934	46065	64421566
Blood alcohol increased	174.32	26.56	50	31051	1132	64466499
Fatigue	154.33	26.56	85	31016	748645	63718986
Pain	151.81	26.56	40	31061	553471	63914160
Pneumonia	145.04	26.56	45	31056	559531	63908100
Dyspnoea	143.20	26.56	85	31016	718589	63749042
Arthralgia	141.88	26.56	22	31079	442238	64025393
Respiratory depression	140.47	26.56	105	30996	23338	64444293
Rash	140.07	26.56	26	31075	458523	64009108
Incorrect route of product administration	138.82	26.56	104	30997	23194	64444437
Somnolence	138.42	26.56	304	30797	203341	64264290
Asphyxia	136.06	26.56	74	31027	9492	64458139
Poisoning	133.34	26.56	99	31002	21780	64445851
Intentional self-injury	132.94	26.56	111	30990	28933	64438698
Anaemia	130.56	26.56	15	31086	378665	64088966
Pyrexia	129.34	26.56	54	31047	558590	63909041
Off label use	128.60	26.56	73	31028	632733	63834898
Agitation	125.17	26.56	182	30919	88185	64379446
Intentional product use issue	124.46	26.56	189	30912	95175	64372456
Drug use disorder	115.36	26.56	57	31044	5997	64461634
Mydriasis	110.99	26.56	77	31024	15235	64452396
Nausea	104.52	26.56	136	30965	785664	63681967
Pain in extremity	104.44	26.56	12	31089	303073	64164558
Condition aggravated	101.80	26.56	27	31074	372399	64095232
Pruritus	101.33	26.56	15	31086	312385	64155246
Loss of consciousness	99.04	26.56	220	30881	148145	64319486
Cough	90.32	26.56	18	31083	302130	64165501
Postmortem blood drug level abnormal	89.32	26.56	26	31075	621	64467010
Headache	88.96	26.56	75	31026	529392	63938239
Suicidal ideation	86.94	26.56	132	30969	66410	64401221
Sopor	86.28	26.56	88	31013	29573	64438058
Alcoholism	86.07	26.56	39	31062	3378	64464253
Depressed level of consciousness	83.87	26.56	145	30956	81291	64386340
Back pain	83.48	26.56	11	31090	250160	64217471
Drug interaction	82.34	26.56	369	30732	361714	64105917
Neutropenia	81.25	26.56	10	31091	239614	64228017
Accidental death	79.79	26.56	38	31063	3687	64463944
Miosis	78.52	26.56	59	31042	13207	64454424
Peripheral swelling	78.07	26.56	6	31095	209147	64258484
Alcohol withdrawal syndrome	77.12	26.56	30	31071	1773	64465858
Metabolic acidosis	72.61	26.56	126	30975	70832	64396799
Tachycardia	72.31	26.56	196	30905	149383	64318248
Asthenia	71.39	26.56	61	31040	427983	64039648
Drug intolerance	71.28	26.56	5	31096	187987	64279644
Constipation	69.91	26.56	13	31088	229324	64238307
Nasopharyngitis	69.45	26.56	7	31094	196066	64271565
Urinary tract infection	68.76	26.56	14	31087	231582	64236049
Pulmonary oedema	64.52	26.56	127	30974	78547	64389084
Drug withdrawal syndrome	63.65	26.56	77	31024	31214	64436417
Sepsis	62.30	26.56	17	31084	230324	64237307
Product dose omission issue	61.62	26.56	10	31091	194737	64272894
Alopecia	61.13	26.56	5	31096	165685	64301946
Malaise	60.70	26.56	61	31040	396186	64071445
Infection	59.61	26.56	9	31092	184871	64282760
Haemoglobin decreased	59.56	26.56	11	31090	195052	64272579
Weight decreased	59.25	26.56	32	31069	285707	64181924
Swelling	58.65	26.56	5	31096	160213	64307418
Hypersensitivity	58.05	26.56	12	31089	196440	64271191
White blood cell count decreased	57.58	26.56	5	31096	157832	64309799
Weight increased	57.22	26.56	16	31085	213332	64254299
Drug abuser	56.21	26.56	35	31066	5773	64461858
Decreased appetite	56.16	26.56	33	31068	281256	64186375
Homicide	55.86	26.56	21	31080	1130	64466501
Shock	54.44	26.56	79	31022	38161	64429470
Abdominal discomfort	54.15	26.56	11	31090	182311	64285320
Drug screen positive	54.13	26.56	34	31067	5695	64461936
Sinusitis	52.21	26.56	5	31096	145923	64321708
Drug hypersensitivity	51.72	26.56	25	31076	237790	64229841
Medication error	51.46	26.56	89	31012	49877	64417754
Pancytopenia	51.04	26.56	5	31096	143304	64324327
Platelet count decreased	50.05	26.56	10	31091	167701	64299930
Opiates positive	49.53	26.56	18	31083	880	64466751
Road traffic accident	48.93	26.56	67	31034	30678	64436953
General physical health deterioration	46.77	26.56	20	31081	204405	64263226
Electrocardiogram QRS complex prolonged	45.78	26.56	37	31064	9207	64458424
Liver injury	44.31	26.56	63	31038	29869	64437762
Product administration error	43.63	26.56	60	31041	27583	64440048
Urticaria	43.50	26.56	9	31092	147308	64320323
Hepatic fibrosis	42.78	26.56	29	31072	5523	64462108
Amnesia	42.10	26.56	80	31021	48189	64419442
Cerebrovascular accident	41.47	26.56	8	31093	137575	64330056
Stomatitis	41.28	26.56	3	31098	109602	64358029
Cardiac failure congestive	40.64	26.56	7	31094	130573	64337058
Musculoskeletal stiffness	39.70	26.56	6	31095	123200	64344431
Abdominal pain	39.36	26.56	56	31045	312319	64155312
Blood ethanol increased	39.34	26.56	14	31087	644	64466987
Muscular weakness	39.25	26.56	7	31094	127331	64340300
Accidental overdose	38.85	26.56	63	31038	33494	64434137
Therapeutic product effect decreased	38.62	26.56	5	31096	115346	64352285
Therapeutic product effect incomplete	38.50	26.56	3	31098	103479	64364152
Sinus tachycardia	38.04	26.56	61	31040	32127	64435504
Unresponsive to stimuli	37.31	26.56	78	31023	50315	64417316
Fall	37.29	26.56	92	31009	416734	64050897
Thrombocytopenia	37.11	26.56	32	31069	223769	64243862
Dizziness	36.90	26.56	97	31004	430066	64037565
Septic shock	36.71	26.56	4	31097	105433	64362198
Dehydration	35.93	26.56	31	31070	216732	64250899
Blood ethanol	35.43	26.56	9	31092	126	64467505
Electrocardiogram QT prolonged	35.29	26.56	101	31000	79347	64388284
Somnambulism	35.26	26.56	25	31076	5116	64462515
Chemical submission	35.22	26.56	10	31091	218	64467413
Dysarthria	35.06	26.56	84	31017	59322	64408309
Oedema peripheral	34.96	26.56	30	31071	210287	64257344
Asthma	34.76	26.56	3	31098	95222	64372409
Abnormal behaviour	34.76	26.56	60	31041	33562	64434069
Amphetamines positive	34.67	26.56	10	31091	231	64467400
Injection site pain	34.61	26.56	6	31095	111402	64356229
Withdrawal syndrome	34.11	26.56	49	31052	23443	64444188
Toxicologic test abnormal	34.11	26.56	15	31086	1210	64466421
Euphoric mood	33.96	26.56	27	31074	6564	64461067
Alcohol intolerance	33.73	26.56	11	31090	387	64467244
Postmortem blood drug level	33.69	26.56	10	31091	256	64467375
Victim of sexual abuse	33.49	26.56	11	31090	396	64467235
Myocardial fibrosis	33.48	26.56	16	31085	1564	64466067
Neuropathy peripheral	33.05	26.56	8	31093	117517	64350114
Rhabdomyolysis	32.71	26.56	108	30993	91618	64376013
Abdominal distension	32.52	26.56	4	31097	95990	64371641
Influenza	32.52	26.56	6	31095	106525	64361106
Erythema	31.93	26.56	26	31075	187044	64280587
Cellulitis	31.49	26.56	4	31097	93653	64373978
Substance dependence	31.49	26.56	11	31090	479	64467152
Bronchitis	31.37	26.56	7	31094	108736	64358895
Brain oedema	30.54	26.56	45	31056	22030	64445601
Acute hepatic failure	30.20	26.56	49	31052	26063	64441568
Respiratory acidosis	30.04	26.56	30	31071	9825	64457806
Chest pain	30.01	26.56	42	31059	235938	64231693
Oropharyngeal pain	29.39	26.56	4	31097	88863	64378768
Seizure	28.49	26.56	157	30944	166735	64300896
Blister	28.37	26.56	3	31098	80964	64386667
Discomfort	28.33	26.56	3	31098	80875	64386756
Impaired driving ability	28.21	26.56	21	31080	4633	64462998
Deep vein thrombosis	27.97	26.56	8	31093	105174	64362457
Physical assault	27.81	26.56	14	31087	1532	64466099
Restlessness	27.63	26.56	60	31041	39725	64427906
Protein C increased	27.17	26.56	7	31094	104	64467527
Dysphagia	26.83	26.56	9	31092	106803	64360828
Renal impairment	26.69	26.56	16	31085	135001	64332630

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	D08AE05	DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Phenol and derivatives
MeSH PA	D000871	Anthelmintics
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000891	Anti-Infective Agents, Local
MeSH PA	D000977	Antiparasitic Agents
MeSH PA	D000980	Antiplatyhelmintic Agents
MeSH PA	D004202	Disinfectants
MeSH PA	D012556	Schistosomicides
CHEBI has role	CHEBI:33904	molluscicides
CHEBI has role	CHEBI:48218	antiseptics
CHEBI has role	CHEBI:48219	disinfectants

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Antiseptic preparation	indication	261276004

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	9.85	acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
5-hydroxytryptamine receptor 2B	GPCR	P41595	5HT2B_HUMAN		Ki	5.93		DRUG MATRIX
Amine oxidase [flavin-containing] A	Enzyme	P21397	AOFA_HUMAN		IC50	5.74		DRUG MATRIX

External reference:

ID	Source
4019458	VUID
N0000147580	NUI
D03473	KEGG_DRUG
4018914	VANDF
4019458	VANDF
C0055463	UMLSCUI
CHEBI:34393	CHEBI
CHEMBL398440	ChEMBL_ID
DB11121	DRUGBANK_ID
2723	PUBCHEM_CID
492	INN_ID
C007027	MESH_SUPPLEMENTAL_RECORD_UI
0F32U78V2Q	UNII
20877	RXNORM
4423	MMSL
72857	MMSL
003140	NDDF
003202	NDDF
126151007	SNOMEDCT_US
398713003	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Antibacterial Hand	HUMAN OTC DRUG LABEL	1	0404-4438	SOAP	6.10 g	TOPICAL	OTC monograph not final	11 sections
Antibacterial	HUMAN OTC DRUG LABEL	1	0404-4441	LIQUID	6.05 g	TOPICAL	OTC monograph not final	11 sections
Antimicrobial Hand Wash	HUMAN OTC DRUG LABEL	1	0404-5987	SOAP	6 mg	TOPICAL	OTC monograph not final	11 sections
Antimicrobial Hand Wash	HUMAN OTC DRUG LABEL	1	0404-5990	SOAP	6 mg	TOPICAL	OTC monograph not final	11 sections
Blistex Foille Medicated First Aid	HUMAN OTC DRUG LABEL	2	10157-9302	OINTMENT	0.10 g	TOPICAL	OTC MONOGRAPH NOT FINAL	13 sections
PC511 ANTIMICROBIAL	HUMAN OTC DRUG LABEL	1	10685-511	SOAP	3 g	TOPICAL	OTC monograph not final	9 sections
PC529 ULTREX	HUMAN OTC DRUG LABEL	1	10685-529	SOAP	2.50 g	TOPICAL	OTC monograph not final	9 sections
PC537 E-2 BRUTE	HUMAN OTC DRUG LABEL	1	10685-537	SOAP	25 g	TOPICAL	OTC monograph not final	9 sections
PC557 PALPON	HUMAN OTC DRUG LABEL	1	10685-557	SOAP	2.50 g	TOPICAL	OTC monograph not final	9 sections
NAMICO ANTISEPTIC HAND CLEANER 557	HUMAN OTC DRUG LABEL	1	10685-978	SOAP	2.50 g	TOPICAL	OTC monograph not final	9 sections
Derma CIDOL 2000	HUMAN OTC DRUG LABEL	1	10802-8081	LIQUID	0.50 g	TOPICAL	OTC monograph not final	8 sections
Kindest Kare Hand Antimicrobial Handwash	HUMAN OTC DRUG LABEL	1	11084-036	SOAP	1 g	TOPICAL	OTC MONOGRAPH NOT FINAL	12 sections
PureBac Foam Wash	HUMAN OTC DRUG LABEL	1	11084-131	LIQUID	0.50 mL	TOPICAL	OTC monograph not final	9 sections
Refresh PureBac Foam	HUMAN OTC DRUG LABEL	1	11084-160	LIQUID	5 g	TOPICAL	OTC monograph not final	10 sections
Acute-Kare Healthcare Personnel Handwash	HUMAN OTC DRUG LABEL	1	11084-800	SOAP	1 g	TOPICAL	OTC monograph not final	12 sections
Chloroxylenol	HUMAN OTC DRUG LABEL	1	11344-562	LIQUID	3.09 g	TOPICAL	OTC monograph not final	12 sections
chloroxylenol	HUMAN OTC DRUG LABEL	1	11344-710	LIQUID	3.09 mg	TOPICAL	OTC monograph not final	11 sections
chloroxylenol	HUMAN OTC DRUG LABEL	1	11344-710	LIQUID	3.09 mg	TOPICAL	OTC monograph not final	11 sections
antibacterial	HUMAN OTC DRUG LABEL	1	11344-713	LIQUID	3 mg	TOPICAL	OTC monograph not final	11 sections
FoamFresh Antibacterial Hand Wash	HUMAN OTC DRUG LABEL	1	11429-1005	LIQUID	2.50 mg	TOPICAL	OTC monograph not final	11 sections
FoamFresh Antibacterial Hand Wash	HUMAN OTC DRUG LABEL	1	11429-1005	LIQUID	2.50 mg	TOPICAL	OTC monograph not final	11 sections
Lemon Drop Gentle Antiseptic	HUMAN OTC DRUG LABEL	1	11429-1006	LIQUID	3 mg	TOPICAL	OTC monograph not final	11 sections
Derma 1 Healthcare Hand Wash	HUMAN OTC DRUG LABEL	1	11429-1007	LIQUID	4 mg	TOPICAL	OTC monograph not final	11 sections
FoamFresh Healthcare Hand Wash	HUMAN OTC DRUG LABEL	1	11429-1008	LIQUID	7.50 mg	TOPICAL	OTC monograph not final	11 sections
Pink Antibacterial	HUMAN OTC DRUG LABEL	1	11429-1009	LIQUID	3 mg	TOPICAL	OTC monograph not final	11 sections
FoamFresh Dye Free Antibacterial Hand Wash	HUMAN OTC DRUG LABEL	1	11429-1010	SOLUTION	2.50 mg	TOPICAL	OTC monograph not final	11 sections
FoamFresh E-2 Sanitizer Cleanser with PCMX	HUMAN OTC DRUG LABEL	1	11429-1011	LIQUID	5 mg	TOPICAL	OTC monograph not final	10 sections
Antiseptic Hand	HUMAN OTC DRUG LABEL	1	16496-544	SOAP	3 mg	TOPICAL	OTC monograph not final	10 sections
BD E-Z SCRUB	HUMAN OTC DRUG LABEL	1	17271-116	SOLUTION	30 mg	TOPICAL	OTC monograph not final	14 sections
BD E-Z Scrub	HUMAN OTC DRUG LABEL	1	17271-502	SOLUTION	30 mg	TOPICAL	OTC monograph not final	14 sections