butamben 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
local anaesthetics 3051 94-25-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • butamben
  • butambene
  • butesin
  • butesine
  • butoform
  • butyl 4-aminobenzoate
  • butylcaine
  • Molecular weight: 193.25
  • Formula: C11H15NO2
  • CLOGP: 2.98
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 52.32
  • ALOGS: -2.76
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000777 Anesthetics
MeSH PA D000779 Anesthetics, Local
MeSH PA D002491 Central Nervous System Agents
MeSH PA D002492 Central Nervous System Depressants
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents
CHEBI has role CHEBI:36333 local anesthetics

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Skin irritation indication 367466007
Itching of skin indication 418363000
Minor Skin Wound Pain indication
Conduction disorder of the heart contraindication 44808001
Decreased respiratory function contraindication 80954004
Open wound contraindication 125643001
Seizure disorder contraindication 128613002
Denuded skin contraindication 418242004




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.5 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019648 VUID
N0000147741 NUI
D00730 KEGG_DRUG
4019648 VANDF
C0054235 UMLSCUI
CHEBI:3231 CHEBI
CHEMBL127516 ChEMBL_ID
DB11148 DRUGBANK_ID
2482 PUBCHEM_CID
C004605 MESH_SUPPLEMENTAL_RECORD_UI
EFW857872Q UNII
19861 RXNORM
14814 MMSL
001368 NDDF
108929004 SNOMEDCT_US
48078005 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Cetacaine Anesthetic HUMAN PRESCRIPTION DRUG LABEL 3 10223-0201 AEROSOL, SPRAY 0.00 g TOPICAL UNAPPROVED DRUG OTHER 12 sections
Cetacaine Anesthetic HUMAN PRESCRIPTION DRUG LABEL 3 10223-0202 SOLUTION 0.00 g TOPICAL UNAPPROVED DRUG OTHER 12 sections
Cetacaine Anesthetic HUMAN PRESCRIPTION DRUG LABEL 3 10223-0202 SOLUTION 0.00 g TOPICAL UNAPPROVED DRUG OTHER 12 sections
Cetacaine Topical Anesthetic HUMAN PRESCRIPTION DRUG LABEL 3 10223-0217 GEL 0.00 g TOPICAL UNAPPROVED DRUG OTHER 11 sections
Cetacaine Topical Anesthetic HUMAN PRESCRIPTION DRUG LABEL 3 10223-0221 GEL 0.00 g TOPICAL UNAPPROVED DRUG OTHER 11 sections
Cetacaine Anesthetic HUMAN PRESCRIPTION DRUG LABEL 3 10223-0225 SOLUTION 0.00 g TOPICAL UNAPPROVED DRUG OTHER 12 sections
Cetacaine Anesthetic HUMAN PRESCRIPTION DRUG LABEL 3 10223-0226 SOLUTION 0.00 g TOPICAL UNAPPROVED DRUG OTHER 12 sections
ONE TOUCH ADVANCED TOPICAL ANESTHETIC GELCOOL MINT HUMAN PRESCRIPTION DRUG LABEL 3 62565-901 GEL 4 mg TOPICAL unapproved drug other 11 sections
ONE TOUCH ADVANCED TOPICAL ANESTHETICSTRAWBERRY ICE HUMAN PRESCRIPTION DRUG LABEL 3 62565-902 GEL 4 mg TOPICAL unapproved drug other 11 sections
ONE TOUCH ADVANCED TOPICAL ANESTHETICBUBBLE GUM HUMAN PRESCRIPTION DRUG LABEL 3 62565-903 GEL 4 mg TOPICAL unapproved drug other 11 sections
ONE TOUCH ADVANCED TOPICAL ANESTHETICCHERRY HUMAN PRESCRIPTION DRUG LABEL 3 62565-904 GEL 4 mg TOPICAL unapproved drug other 11 sections