benzethonium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
quaternary ammonium compounds	3018	121-54-0

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: benzethonium benzethionium chloride benzethonium chloride benzetonium chloride	Bactericidal cationic quaternary ammonium surfactant used as a topical anti-infective agent. It is an ingredient in medicaments, deodorants, mouthwashes, etc., and is used to disinfect apparatus, etc., in the food processing and pharmaceutical industries, in surgery, and also as a preservative. The compound is toxic orally as a result of neuromuscular blockade. Molecular weight: 412.64 Formula: C27H42NO2 CLOGP: 4.29 LIPINSKI: 0 HAC: 3 HDO: 0 TPSA: 18.46 ALOGS: -7.78 ROTB: 12

Molecule

Description

Molfile Inchi Smiles

Synonyms:

benzethonium
benzethionium chloride
benzethonium chloride
benzetonium chloride

Bactericidal cationic quaternary ammonium surfactant used as a topical anti-infective agent. It is an ingredient in medicaments, deodorants, mouthwashes, etc., and is used to disinfect apparatus, etc., in the food processing and pharmaceutical industries, in surgery, and also as a preservative. The compound is toxic orally as a result of neuromuscular blockade.

Molecular weight: 412.64
Formula: C27H42NO2
CLOGP: 4.29
LIPINSKI: 0
HAC: 3
HDO: 0
TPSA: 18.46
ALOGS: -7.78
ROTB: 12

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Completed suicide	6791.66	20.60	2281	17831	143392	63325518
Toxicity to various agents	4103.71	20.60	1833	18279	245417	63223493
Drug abuse	2179.48	20.60	828	19284	71690	63397220
Cardio-respiratory arrest	1303.57	20.60	543	19569	59416	63409494
Intentional overdose	1189.42	20.60	542	19570	73610	63395300
Overdose	872.32	20.60	508	19604	114570	63354340
Suicide attempt	739.24	20.60	368	19744	60550	63408360
Alcohol interaction	508.38	20.60	124	19988	2285	63466625
Suspected suicide	456.03	20.60	141	19971	6427	63462483
Respiratory arrest	368.39	20.60	188	19924	32457	63436453
Intentional product misuse	367.86	20.60	233	19879	60684	63408226
Cardiac arrest	349.13	20.60	265	19847	92280	63376630
Death	291.95	20.60	465	19647	373916	63094994
Exposure to toxic agent	281.39	20.60	94	20018	5493	63463417
Alcohol poisoning	267.72	20.60	71	20041	1848	63467062
Alcohol use	220.53	20.60	62	20050	2017	63466893
Coma	211.48	20.60	170	19942	64194	63404716
Somnolence	186.41	20.60	255	19857	178430	63290480
Alcohol abuse	183.00	20.60	54	20058	2092	63466818
Drug ineffective	158.69	20.60	67	20045	1044698	62424212
Agitation	126.39	20.60	123	19989	59634	63409276
Pain	123.04	20.60	41	20071	740587	62728323
Poisoning	118.07	20.60	66	20046	13634	63455276
Poisoning deliberate	116.05	20.60	61	20051	11157	63457753
Mydriasis	115.19	20.60	62	20050	11894	63457016
Fatigue	108.23	20.60	75	20037	887953	62580957
Diarrhoea	108.08	20.60	46	20066	715320	62753590
Loss of consciousness	104.49	20.60	156	19956	117965	63350945
Arthralgia	100.88	20.60	28	20084	569682	62899228
Alcoholism	97.16	20.60	32	20080	1786	63467124
Substance abuse	95.58	20.60	41	20071	4766	63464144
Seizure	89.67	20.60	155	19957	132479	63336431
Myocarditis	86.96	20.60	49	20063	10276	63458634
Blood alcohol increased	85.61	20.60	23	20089	629	63468281
Postmortem blood drug level abnormal	83.57	20.60	20	20092	338	63468572
Drug dependence	81.03	20.60	65	20047	24418	63444492
Intentional self-injury	78.29	20.60	65	20047	25622	63443288
Rash	75.56	20.60	42	20070	560829	62908081
Victim of sexual abuse	75.28	20.60	21	20091	663	63468247
Alopecia	73.46	20.60	10	20102	337526	63131384
Joint swelling	73.02	20.60	9	20103	327657	63141253
Abdominal discomfort	71.05	20.60	9	20103	320876	63148034
Suicidal ideation	70.89	20.60	93	20019	62328	63406582
Chemical submission	67.10	20.60	16	20096	266	63468644
Drug use disorder	65.89	20.60	32	20080	4952	63463958
Drug interaction	63.84	20.60	188	19924	228943	63239967
Pyrexia	63.65	20.60	35	20077	470443	62998467
Dyspnoea	63.25	20.60	70	20042	661243	62807667
Drug intolerance	62.93	20.60	11	20101	308650	63160260
Aggression	60.51	20.60	54	20058	23444	63445466
Condition aggravated	60.35	20.60	26	20086	402191	63066719
Off label use	59.58	20.60	76	20036	674386	62794524
Depressed level of consciousness	59.20	20.60	85	20027	61993	63406917
Broncholithiasis	58.37	20.60	14	20098	239	63468671
Swelling	57.94	20.60	9	20103	275369	63193541
Asthenia	55.66	20.60	26	20086	383578	63085332
Drug withdrawal syndrome	55.63	20.60	55	20057	27139	63441771
Congestive hepatopathy	54.91	20.60	24	20088	2918	63465992
Lymph node calcification	54.59	20.60	14	20098	318	63468592
Pneumonia	52.26	20.60	41	20071	456726	63012184
Somnambulism	51.31	20.60	28	20084	5515	63463395
Arthropathy	50.95	20.60	7	20105	234785	63234125
Metabolic acidosis	50.93	20.60	67	20045	45002	63423908
Pain in extremity	50.38	20.60	21	20091	331465	63137445
Drug hypersensitivity	50.00	20.60	18	20094	310669	63158241
Electrocardiogram ST segment elevation	48.29	20.60	24	20088	3903	63465007
Nasopharyngitis	47.76	20.60	11	20101	254246	63214664
Synovitis	47.34	20.60	3	20109	186915	63281995
Anaemia	47.22	20.60	17	20095	293413	63175497
Product administration interrupted	46.35	20.60	25	20087	4811	63464099
Tachycardia	46.14	20.60	110	20002	118046	63350864
Systemic lupus erythematosus	45.87	20.60	6	20106	208912	63259998
Pruritus	45.86	20.60	29	20083	361424	63107486
Asphyxia	45.82	20.60	27	20085	6154	63462756
Rheumatoid arthritis	45.70	20.60	12	20100	253807	63215103
Headache	43.82	20.60	84	20028	633157	62835753
Peripheral swelling	43.48	20.60	15	20097	265927	63202983
Electrocardiogram QT prolonged	43.39	20.60	72	20040	59458	63409452
Neutropenia	40.99	20.60	4	20108	175001	63293909
Substance use disorder	40.34	20.60	10	20102	197	63468713
Sopor	40.18	20.60	42	20070	22122	63446788
Victim of chemical submission	39.36	20.60	12	20100	520	63468390
Electrocardiogram QRS complex prolonged	39.00	20.60	24	20088	5914	63462996
Weight increased	38.85	20.60	17	20095	260775	63208135
Product dose omission issue	38.67	20.60	13	20099	234300	63234610
Liver injury	38.60	20.60	69	20043	60451	63408459
Sinusitis	38.42	20.60	12	20100	226641	63242269
Amnesia	37.56	20.60	65	20047	55520	63413390
Protein C increased	34.90	20.60	8	20104	111	63468799
Hepatic failure	34.24	20.60	49	20063	35607	63433303
Homicide	34.19	20.60	10	20102	375	63468535
Discomfort	34.00	20.60	6	20106	167368	63301542
Urinary tract infection	33.87	20.60	21	20091	264663	63204247
Bronchial wall thickening	33.85	20.60	14	20098	1485	63467425
Hepatic encephalopathy	33.23	20.60	28	20084	11254	63457656
Stomatitis	32.93	20.60	3	20109	138722	63330188
Musculoskeletal stiffness	32.70	20.60	9	20103	184609	63284301
Abnormal behaviour	32.56	20.60	37	20075	21389	63447521
Cough	32.53	20.60	27	20085	292716	63176194
Hypersensitivity	32.51	20.60	27	20085	292658	63176252
Constipation	31.43	20.60	16	20096	224927	63243983
Lichen nitidus	31.25	20.60	7	20105	87	63468823
Infection	31.00	20.60	17	20095	229156	63239754
Substance dependence	30.62	20.60	8	20104	196	63468714
Accidental death	30.14	20.60	14	20098	1962	63466948
Treatment failure	29.59	20.60	13	20099	199030	63269880
Induced abortion failed	28.94	20.60	8	20104	244	63468666
Wound	28.84	20.60	8	20104	163255	63305655
Pericarditis	28.34	20.60	4	20108	131575	63337335
Ventricular tachycardia	27.84	20.60	33	20079	19946	63448964
Sinus tachycardia	27.29	20.60	36	20076	24232	63444678
Congenital umbilical hernia	27.23	20.60	8	20104	305	63468605
Hypotension	27.05	20.60	163	19949	272441	63196469
Shock	26.68	20.60	35	20077	23428	63445482
Lower respiratory tract infection	26.32	20.60	5	20107	132302	63336608
Malaise	26.31	20.60	58	20054	415896	63053014
Arthritis	26.24	20.60	3	20109	115918	63352992
Aspiration	26.09	20.60	24	20088	10827	63458083
Disinhibition	26.05	20.60	10	20102	873	63468037
Disease progression	25.82	20.60	4	20108	122754	63346156
Nausea	25.82	20.60	162	19950	854309	62614601
Sexual abuse	25.21	20.60	7	20105	217	63468693
Road traffic accident	24.95	20.60	43	20069	36589	63432321
Respiratory depression	24.87	20.60	26	20086	13689	63455221
Febrile neutropenia	24.60	20.60	4	20108	118445	63350465
Encephalopathy	24.58	20.60	44	20068	38576	63430334
Hyperlipasaemia	24.39	20.60	9	20103	704	63468206
Toxicologic test abnormal	24.30	20.60	9	20103	712	63468198
White blood cell count decreased	24.22	20.60	7	20105	139097	63329813
Blood ethanol increased	24.12	20.60	6	20106	120	63468790
Areflexia	24.11	20.60	14	20098	3104	63465806
Thrombocytopenia	23.88	20.60	9	20103	151148	63317762
Blister	23.60	20.60	6	20106	129808	63339102
Alcoholic	23.60	20.60	5	20107	47	63468863
Decreased appetite	23.43	20.60	27	20085	251025	63217885
Postmortem blood drug level	23.36	20.60	6	20106	137	63468773
Dizziness	23.24	20.60	65	20047	429860	63039050
Drug level increased	22.94	20.60	32	20080	22704	63446206
Euphoric mood	22.92	20.60	16	20096	4871	63464039
Sepsis	22.75	20.60	10	20102	153113	63315797
Impaired healing	22.36	20.60	3	20109	102539	63366371
Accidental overdose	22.33	20.60	32	20080	23277	63445633
Drug screen positive	22.15	20.60	14	20098	3615	63465295
Unresponsive to stimuli	22.13	20.60	39	20073	33777	63435133
Back pain	21.96	20.60	31	20081	264114	63204796
Injection site pain	21.75	20.60	7	20105	129793	63339117
Opiates positive	21.46	20.60	7	20105	379	63468531
Amphetamines positive	21.31	20.60	6	20106	196	63468714
Loss of personal independence in daily activities	20.85	20.60	3	20109	97287	63371623
Haemoglobin decreased	20.84	20.60	10	20102	145475	63323435
Cardiogenic shock	20.78	20.60	27	20085	17905	63451005
General physical health deterioration	20.65	20.60	20	20092	201382	63267528
Renal tubular necrosis	20.62	20.60	22	20090	11856	63457054
Weight decreased	20.61	20.60	35	20077	276763	63192147

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Drug abuse	5573.12	23.43	2193	21974	96903	34835861
Completed suicide	4071.82	23.43	1752	22415	96416	34836348
Toxicity to various agents	3662.83	23.43	2040	22127	198322	34734442
Cardio-respiratory arrest	870.10	23.43	516	23651	54757	34878007
Intentional overdose	794.16	23.43	448	23719	43226	34889538
Overdose	626.17	23.43	511	23656	90548	34842216
Alcohol abuse	554.95	23.43	182	23985	4508	34928256
Intentional product misuse	530.91	23.43	352	23815	45259	34887505
Alcohol interaction	520.72	23.43	155	24012	2758	34930006
Suicide attempt	467.51	23.43	307	23860	38809	34893955
Suspected suicide	392.86	23.43	141	24026	4607	34928157
Drug dependence	356.52	23.43	217	23950	24000	34908764
Alcohol poisoning	336.48	23.43	117	24050	3476	34929288
Substance abuse	288.81	23.43	129	24038	7512	34925252
Coma	247.20	23.43	224	23943	45454	34887310
Exposure to toxic agent	216.05	23.43	85	24082	3590	34929174
Asphyxia	210.14	23.43	100	24067	6735	34926029
Respiratory depression	204.80	23.43	132	24035	16113	34916651
Aggression	198.92	23.43	185	23982	38779	34893985
Respiratory arrest	195.37	23.43	159	24008	27884	34904880
Poisoning deliberate	176.89	23.43	93	24074	7751	34925013
Alcohol use	172.28	23.43	70	24097	3218	34929546
Diarrhoea	143.27	23.43	46	24121	389866	34542898
Fractional exhaled nitric oxide increased	127.96	23.43	42	24125	1040	34931724
Poisoning	124.42	23.43	87	24080	12139	34920625
Pneumonia	122.56	23.43	49	24118	362578	34570186
Fatigue	114.40	23.43	57	24110	370596	34562168
Blood alcohol increased	113.90	23.43	36	24131	787	34931977
Drug ineffective	112.61	23.43	91	24076	456660	34476104
Incorrect route of product administration	107.20	23.43	86	24081	14759	34918005
Pyrexia	106.09	23.43	49	24118	332964	34599800
Cardiac arrest	105.48	23.43	216	23951	95943	34836821
Substance use disorder	103.37	23.43	33	24134	746	34932018
Anaemia	99.98	23.43	20	24147	233315	34699449
Intentional product use issue	99.49	23.43	161	24006	59655	34873109
Death	97.96	23.43	536	23631	397513	34535251
Plantar fasciitis	97.16	23.43	41	24126	2075	34930689
Drug use disorder	92.51	23.43	49	24118	4142	34928622
Neutropenia	91.42	23.43	4	24163	156774	34775990
Sensation of foreign body	89.46	23.43	42	24125	2741	34930023
Myoglobin blood increased	89.16	23.43	43	24124	2980	34929784
Depressed level of consciousness	87.70	23.43	127	24040	42714	34890050
Drug withdrawal syndrome	87.57	23.43	87	24080	19747	34913017
Miosis	83.62	23.43	62	24105	9473	34923291
Suicidal ideation	83.07	23.43	120	24047	40268	34892496
Off label use	82.18	23.43	102	24065	419422	34513342
Rash	80.32	23.43	27	24140	222725	34710039
Prescription drug used without a prescription	80.19	23.43	36	24131	2118	34930646
Intentional self-injury	75.28	23.43	68	24099	13703	34919061
Agitation	73.88	23.43	138	24029	57261	34875503
Mydriasis	67.85	23.43	49	24118	7188	34925576
Alcohol withdrawal syndrome	65.59	23.43	28	24139	1458	34931306
Disease progression	62.18	23.43	3	24164	108074	34824690
Pain	62.18	23.43	32	24135	204643	34728121
Brain natriuretic peptide increased	61.63	23.43	42	24125	5617	34927147
Accidental death	60.76	23.43	31	24136	2425	34930339
Constipation	60.17	23.43	11	24156	136971	34795793
Nausea	60.02	23.43	89	24078	339819	34592945
Drug interaction	59.87	23.43	311	23856	225635	34707129
Sepsis	58.60	23.43	21	24146	166540	34766224
Asthenia	56.38	23.43	52	24115	245199	34687565
Arthralgia	55.61	23.43	24	24143	170017	34762747
Medication error	55.55	23.43	78	24089	25487	34907277
Alcoholism	55.27	23.43	31	24136	2934	34929830
Platelet count decreased	53.91	23.43	9	24158	119708	34813056
Secretion discharge	53.13	23.43	39	24128	5866	34926898
Dyspnoea	51.90	23.43	115	24052	376667	34556097
Pain in extremity	51.75	23.43	12	24155	126501	34806263
Alcohol intolerance	51.48	23.43	17	24150	429	34932335
White blood cell count decreased	50.85	23.43	4	24163	95441	34837323
Haemoglobin decreased	50.31	23.43	11	24156	120761	34812003
Road traffic accident	49.97	23.43	61	24106	17389	34915375
Drug screen positive	49.56	23.43	32	24135	3911	34928853
Decreased appetite	49.06	23.43	27	24140	166365	34766399
General physical health deterioration	48.95	23.43	14	24153	128255	34804509
Withdrawal syndrome	48.37	23.43	51	24116	12404	34920360
Pancytopenia	47.98	23.43	5	24162	95152	34837612
Amnesia	47.56	23.43	74	24093	26489	34906275
Tachycardia	46.95	23.43	147	24020	84625	34848139
Sopor	45.90	23.43	49	24118	12087	34920677
Infection	45.27	23.43	5	24162	90910	34841854
Ex-drug abuser	44.81	23.43	12	24155	142	34932622
Loss of consciousness	44.54	23.43	142	24025	82525	34850239
Product dose omission issue	43.98	23.43	14	24153	119697	34813067
Malignant neoplasm progression	43.44	23.43	5	24162	88041	34844723
Metabolic acidosis	43.02	23.43	94	24073	43586	34889178
Back pain	41.72	23.43	16	24151	121773	34810991
Weight decreased	40.92	23.43	37	24130	176264	34756500
Exostosis	39.82	23.43	30	24137	4693	34928071
Cardiac failure congestive	38.06	23.43	6	24161	83264	34849500
Neuropathy peripheral	38.05	23.43	6	24161	83257	34849507
Oedema peripheral	37.44	23.43	18	24149	119794	34812970
Thrombocytopenia	37.21	23.43	32	24135	156215	34776549
Urinary tract infection	36.37	23.43	7	24160	84074	34848690
Obstructive airways disorder	36.25	23.43	49	24118	15445	34917319
Peripheral swelling	36.17	23.43	5	24162	76536	34856228
Opiates positive	36.12	23.43	14	24153	567	34932197
Hepatic fibrosis	36.06	23.43	28	24139	4579	34928185
Somnolence	35.85	23.43	162	24005	110954	34821810
Drug abuser	35.31	23.43	26	24141	3928	34928836
Impaired driving ability	34.65	23.43	22	24145	2611	34930153
Brain oedema	34.31	23.43	45	24122	13776	34918988
Interstitial lung disease	34.04	23.43	3	24164	65279	34867485
Pulmonary oedema	33.61	23.43	90	24077	47439	34885325
Cerebrovascular accident	32.82	23.43	9	24158	84802	34847962
Abdominal pain	32.70	23.43	39	24128	163579	34769185
Homicide	32.60	23.43	15	24152	934	34931830
COVID-19	32.41	23.43	7	24160	77543	34855221
Dizziness	32.26	23.43	64	24103	218457	34714307
Choroiditis	32.00	23.43	16	24151	1199	34931565
Dehydration	31.70	23.43	26	24141	129943	34802821
Foetal alcohol syndrome	31.58	23.43	9	24158	136	34932628
Myocardial infarction	31.07	23.43	23	24144	121062	34811702
Septic shock	31.02	23.43	6	24161	71828	34860936
Drug intolerance	30.36	23.43	3	24164	59567	34873197
Physical assault	29.92	23.43	15	24152	1130	34931634
Cardiac failure	29.60	23.43	13	24154	91235	34841529
Pleural effusion	29.13	23.43	10	24157	81536	34851228
Dysarthria	28.89	23.43	70	24097	34712	34898052
Blood ethanol	28.12	23.43	8	24159	120	34932644
Malaise	26.92	23.43	55	24112	185770	34746994
Myocardial fibrosis	26.43	23.43	14	24153	1183	34931581
Behaviour disorder	26.35	23.43	24	24143	4886	34927878
Muscular weakness	25.93	23.43	9	24158	72888	34859876
Pulmonary embolism	25.79	23.43	15	24152	89731	34843033
Blood creatinine increased	25.74	23.43	17	24150	94959	34837805
Unresponsive to stimuli	25.64	23.43	58	24109	27511	34905253
Sensorimotor disorder	25.19	23.43	10	24157	432	34932332
Gun shot wound	24.36	23.43	13	24154	1115	34931649
Pruritus	24.17	23.43	38	24129	141943	34790821
Dextrocardia	24.02	23.43	7	24160	115	34932649
Suicidal behaviour	23.51	23.43	14	24153	1483	34931281
Weight increased	23.44	23.43	18	24149	93015	34839749

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Completed suicide	10306.78	19.11	3983	34752	241784	79463869
Drug abuse	7761.82	19.11	2908	35827	159783	79545870
Toxicity to various agents	7596.08	19.11	3773	34962	417767	79287886
Cardio-respiratory arrest	2151.02	19.11	1048	37687	107462	79598191
Intentional overdose	1638.74	19.11	866	37869	105094	79600559
Overdose	1250.06	19.11	889	37846	183317	79522336
Alcohol interaction	876.24	19.11	241	38494	4633	79701020
Intentional product misuse	864.02	19.11	551	38184	94614	79611039
Suspected suicide	778.07	19.11	263	38472	10313	79695340
Suicide attempt	764.63	19.11	485	38250	82447	79623206
Alcohol abuse	572.71	19.11	177	38558	5186	79700467
Respiratory arrest	541.17	19.11	341	38394	57209	79648444
Alcohol poisoning	518.55	19.11	160	38575	4661	79700992
Death	489.50	19.11	935	37800	565579	79140074
Exposure to toxic agent	479.83	19.11	177	38558	8981	79696672
Coma	427.06	19.11	369	38366	100280	79605373
Drug dependence	417.15	19.11	255	38480	40514	79665139
Cardiac arrest	409.85	19.11	460	38275	171636	79534017
Alcohol use	327.31	19.11	113	38622	4718	79700935
Substance abuse	325.42	19.11	139	38596	10387	79695266
Poisoning deliberate	279.01	19.11	150	38585	18678	79686975
Drug ineffective	271.77	19.11	94	38641	1080819	78624834
Diarrhoea	230.85	19.11	71	38664	880418	78825235
Asphyxia	221.57	19.11	110	38625	11610	79694043
Poisoning	220.59	19.11	143	38592	25129	79680524
Aggression	216.24	19.11	187	38548	50771	79654882
Fatigue	202.45	19.11	100	38635	929627	78776026
Pain	191.15	19.11	53	38682	703749	79001904
Respiratory depression	187.95	19.11	134	38601	27496	79678157
Agitation	178.73	19.11	231	38504	99484	79606169
Blood alcohol increased	178.23	19.11	52	38683	1243	79704410
Arthralgia	175.23	19.11	33	38702	571770	79133883
Off label use	154.46	19.11	129	38606	907086	78798567
Mydriasis	151.92	19.11	99	38636	17544	79688109
Pyrexia	150.53	19.11	71	38664	678638	79027015
Drug use disorder	148.30	19.11	76	38659	8575	79697078
Rash	140.21	19.11	53	38682	578305	79127348
Substance use disorder	139.48	19.11	40	38695	898	79704755
Pneumonia	138.98	19.11	74	38661	660172	79045481
Dyspnoea	137.23	19.11	129	38606	856896	78848757
Somnolence	135.68	19.11	334	38401	238647	79467006
Depressed level of consciousness	135.66	19.11	199	38536	96453	79609200
Intentional self-injury	125.56	19.11	113	38622	32306	79673347
Incorrect route of product administration	124.09	19.11	116	38619	34813	79670840
Anaemia	119.70	19.11	34	38701	444981	79260672
Nausea	110.48	19.11	185	38550	957011	78748642
Joint swelling	109.52	19.11	8	38727	288638	79417015
Neutropenia	109.09	19.11	8	38727	287702	79417951
Loss of consciousness	108.57	19.11	247	38488	167696	79537957
Miosis	108.34	19.11	77	38658	15712	79689941
Alcoholism	98.27	19.11	44	38691	3679	79701974
Drug interaction	97.92	19.11	430	38305	414753	79290900
Pain in extremity	97.72	19.11	28	38707	364510	79341143
Metabolic acidosis	97.60	19.11	157	38578	82372	79623281
Febrile neutropenia	95.02	19.11	4	38731	230995	79474658
Infusion related reaction	94.66	19.11	4	38731	230233	79475420
Suicidal ideation	92.70	19.11	147	38588	76193	79629460
Accidental death	92.30	19.11	44	38691	4247	79701406
Asthenia	91.54	19.11	69	38666	511620	79194033
Postmortem blood drug level abnormal	88.85	19.11	26	38709	628	79705025
Intentional product use issue	88.79	19.11	215	38520	151897	79553756
Cough	88.12	19.11	34	38701	366755	79338898
Drug intolerance	88.04	19.11	12	38723	264107	79441546
Nasopharyngitis	85.90	19.11	11	38724	253870	79451783
Abdominal discomfort	79.86	19.11	13	38722	250714	79454939
Prescription drug used without a prescription	79.16	19.11	39	38696	4046	79701607
Constipation	79.11	19.11	20	38715	283030	79422623
Pruritus	78.90	19.11	47	38688	394601	79311052
Alopecia	78.32	19.11	10	38725	231345	79474308
Headache	77.44	19.11	124	38611	653648	79052005
Peripheral swelling	77.41	19.11	18	38717	269599	79436054
Tachycardia	77.08	19.11	225	38510	177543	79528110
Condition aggravated	77.00	19.11	78	38657	501046	79204607
Urinary tract infection	75.56	19.11	20	38715	274492	79431161
Electrocardiogram QRS complex prolonged	72.41	19.11	52	38683	10781	79694872
Drug withdrawal syndrome	71.03	19.11	86	38649	34632	79671021
Arthropathy	69.84	19.11	4	38731	177107	79528546
Drug hypersensitivity	69.66	19.11	29	38706	298887	79406766
Weight increased	69.49	19.11	24	38711	277362	79428291
General physical health deterioration	68.63	19.11	24	38711	275214	79430439
Rheumatoid arthritis	68.22	19.11	10	38725	208460	79497193
Alcohol withdrawal syndrome	66.95	19.11	28	38707	1983	79703670
Product dose omission issue	66.32	19.11	19	38716	247518	79458135
Disease progression	64.80	19.11	7	38728	184355	79521298
Weight decreased	64.62	19.11	47	38688	355151	79350502
White blood cell count decreased	64.06	19.11	8	38727	188280	79517373
Decreased appetite	64.01	19.11	44	38691	342374	79363279
Treatment failure	63.85	19.11	5	38730	170481	79535172
Sepsis	63.00	19.11	26	38709	269402	79436251
Pulmonary oedema	62.84	19.11	135	38600	88119	79617534
Infection	62.13	19.11	20	38715	241692	79463961
Chemical submission	62.10	19.11	17	38718	320	79705333
Swelling	61.14	19.11	15	38720	216696	79488957
Malaise	60.73	19.11	90	38645	489779	79215874
Sopor	59.90	19.11	77	38658	32933	79672720
Seizure	59.22	19.11	214	38521	188620	79517033
Hypersensitivity	58.62	19.11	27	38708	262212	79443441
Opiates positive	58.51	19.11	21	38714	983	79704670
Back pain	58.31	19.11	38	38697	304142	79401511
Synovitis	57.65	19.11	4	38731	150730	79554923
Dizziness	56.66	19.11	106	38629	526335	79179318
Pancytopenia	56.48	19.11	7	38728	165738	79539915
Sinusitis	56.20	19.11	13	38722	195488	79510165
Haemoglobin decreased	56.00	19.11	19	38716	222100	79483553
Homicide	55.10	19.11	21	38714	1165	79704488
Drug abuser	54.86	19.11	35	38700	5978	79699675
Drug screen positive	54.59	19.11	35	38700	6028	79699625
Urticaria	53.87	19.11	12	38723	185189	79520464
Stomatitis	53.06	19.11	5	38730	146752	79558901
Medication error	52.35	19.11	108	38627	68534	79637119
Musculoskeletal stiffness	51.59	19.11	11	38724	174997	79530656
Victim of sexual abuse	50.27	19.11	16	38719	516	79705137
Platelet count decreased	50.21	19.11	16	38719	194648	79511005
Broncholithiasis	48.30	19.11	13	38722	229	79705424
Withdrawal syndrome	47.72	19.11	62	38673	26792	79678861
Therapeutic product effect decreased	46.89	19.11	11	38724	163852	79541801
Blood ethanol	46.82	19.11	12	38723	173	79705480
Shock	46.29	19.11	79	38656	43469	79662184
Malignant neoplasm progression	45.71	19.11	6	38729	135984	79569669
Amnesia	45.50	19.11	97	38638	62960	79642693
Abdominal pain	44.99	19.11	75	38660	389494	79316159
Electrocardiogram QT prolonged	44.64	19.11	120	38615	90266	79615387
Thrombocytopenia	44.55	19.11	38	38697	265221	79440432
Cardiac failure congestive	43.96	19.11	8	38727	142394	79563259
Amphetamines positive	43.85	19.11	13	38722	329	79705324
Postmortem blood drug level	43.63	19.11	13	38722	335	79705318
Brain oedema	42.84	19.11	57	38678	25206	79680447
Congestive hepatopathy	42.81	19.11	27	38708	4520	79701133
Septic shock	42.29	19.11	5	38730	122796	79582857
Blood ethanol increased	42.29	19.11	15	38720	678	79704975
Systemic lupus erythematosus	41.56	19.11	5	38730	121144	79584509
Lymph node calcification	41.37	19.11	13	38722	402	79705251
Abdominal distension	40.89	19.11	5	38730	119645	79586008
Road traffic accident	39.72	19.11	74	38661	43590	79662063
Product administration error	39.57	19.11	62	38673	31784	79673869
Somnambulism	39.47	19.11	28	38707	5693	79699960
Unresponsive to stimuli	39.31	19.11	85	38650	55703	79649950
Pericarditis	39.18	19.11	3	38732	104233	79601420
Hand deformity	39.04	19.11	3	38732	103916	79601737
Injection site pain	38.59	19.11	8	38727	129830	79575823
Accidental overdose	38.43	19.11	69	38666	39512	79666141
Cerebrovascular accident	37.90	19.11	14	38721	155278	79550375
Interstitial lung disease	37.77	19.11	5	38730	112595	79593058
Victim of chemical submission	37.68	19.11	13	38722	541	79705112
Rhabdomyolysis	37.65	19.11	123	38612	103008	79602645
COVID-19	37.18	19.11	15	38720	157659	79547994
Electrocardiogram ST segment elevation	35.96	19.11	31	38704	8366	79697287
Loss of personal independence in daily activities	35.77	19.11	4	38731	102576	79603077
Toxicologic test abnormal	35.66	19.11	16	38719	1344	79704309
Respiratory acidosis	35.61	19.11	35	38700	11165	79694488
Hepatic fibrosis	35.57	19.11	29	38706	7251	79698402
Alcohol intolerance	35.41	19.11	12	38723	473	79705180
Muscular weakness	35.21	19.11	17	38718	160712	79544941
Acute hepatic failure	35.18	19.11	57	38678	30056	79675597
Behaviour disorder	34.81	19.11	27	38708	6286	79699367
Abnormal behaviour	34.73	19.11	63	38672	36358	79669295
Sinus tachycardia	34.13	19.11	63	38672	36845	79668808
Hypoaesthesia	33.54	19.11	23	38712	179329	79526324
Pulmonary embolism	33.47	19.11	21	38714	171633	79534020
Mobility decreased	33.40	19.11	9	38726	122166	79583487
Musculoskeletal pain	33.26	19.11	5	38730	102349	79603304
Discomfort	32.97	19.11	10	38725	125607	79580046
Influenza	32.80	19.11	11	38724	129595	79576058
Fall	32.77	19.11	124	38611	487505	79218148
Pulmonary congestion	32.62	19.11	52	38683	27048	79678605
Oedema	32.33	19.11	9	38726	119571	79586082
Blister	32.29	19.11	9	38726	119467	79586186
Choroiditis	32.28	19.11	15	38720	1366	79704287
Myocardial fibrosis	32.09	19.11	16	38719	1702	79703951
Haematochezia	31.64	19.11	3	38732	87642	79618011
Herpes zoster	31.54	19.11	4	38731	93079	79612574
Osteoarthritis	31.48	19.11	3	38732	87306	79618347
Bradypnoea	31.46	19.11	25	38710	6027	79699626
Dehydration	31.28	19.11	45	38690	248142	79457511
Wheezing	31.14	19.11	9	38726	116655	79588998
Substance dependence	31.10	19.11	11	38724	493	79705160
Lower respiratory tract infection	30.95	19.11	12	38723	129208	79576445
Arthritis	30.41	19.11	9	38726	114871	79590782
Physical assault	30.08	19.11	15	38720	1596	79704057
Euphoric mood	30.04	19.11	27	38708	7699	79697954
Oropharyngeal pain	30.00	19.11	8	38727	109345	79596308
Bronchitis	29.88	19.11	13	38722	130631	79575022
Liver injury	29.81	19.11	77	38658	56537	79649116
Accidental poisoning	29.68	19.11	15	38720	1642	79704011
Hypothermia	29.26	19.11	45	38690	22701	79682952
C-reactive protein increased	29.26	19.11	13	38722	129014	79576639
Abdominal pain upper	28.78	19.11	40	38695	223779	79481874
Dysarthria	28.70	19.11	85	38650	67537	79638116
Chest pain	28.45	19.11	59	38676	282245	79423408
Upper respiratory tract infection	28.40	19.11	5	38730	91163	79614490
Chills	28.08	19.11	22	38713	160212	79545441
Lichen nitidus	28.06	19.11	7	38728	90	79705563
Deep vein thrombosis	27.71	19.11	12	38723	120907	79584746
Leukopenia	27.60	19.11	11	38724	116502	79589151
Drug level increased	27.46	19.11	60	38675	39591	79666062
Protein C increased	27.12	19.11	7	38728	104	79705549
Delirium tremens	27.02	19.11	11	38724	727	79704926
Oedema peripheral	26.90	19.11	51	38684	252237	79453416
Neuropathy peripheral	26.58	19.11	18	38717	141287	79564366
Myocarditis	26.57	19.11	42	38693	21691	79683962
Neck pain	26.14	19.11	3	38732	75414	79630239
Impaired driving ability	25.26	19.11	21	38714	5394	79700259
Colitis	25.20	19.11	3	38732	73304	79632349
Dysphagia	25.14	19.11	14	38721	122122	79583531
Suicidal behaviour	25.00	19.11	17	38718	3230	79702423
Therapy non-responder	24.86	19.11	7	38728	92298	79613355
Erythema	24.82	19.11	44	38691	223246	79482407
Myocardial infarction	24.59	19.11	32	38703	184097	79521556
Restlessness	24.24	19.11	63	38672	46429	79659224
Sudden death	24.13	19.11	41	38694	22470	79683183
Hepatic enzyme increased	24.12	19.11	32	38703	182578	79523075
Exposure via ingestion	24.00	19.11	20	38715	5154	79700499
Inappropriate schedule of product administration	23.85	19.11	18	38717	133610	79572043
Neutrophil count decreased	23.73	19.11	8	38727	93951	79611702
Fluid retention	23.65	19.11	3	38732	69806	79635847
Serotonin syndrome	23.46	19.11	61	38674	44966	79660687
Thrombosis	23.36	19.11	6	38729	84094	79621559
Bezoar	22.93	19.11	15	38720	2673	79702980
Migraine	22.89	19.11	7	38728	87486	79618167
Injection site erythema	22.86	19.11	5	38730	78192	79627461
Induced abortion failed	22.84	19.11	7	38728	199	79705454
Epistaxis	22.64	19.11	13	38722	111502	79594151
Incoherent	22.54	19.11	23	38712	7669	79697984
Visceral oedema	22.01	19.11	6	38729	111	79705542
Coma scale abnormal	21.97	19.11	24	38711	8654	79696999
Inflammation	21.97	19.11	9	38726	93744	79611909
Asthma	21.89	19.11	20	38715	135075	79570578
Sensorimotor disorder	21.80	19.11	10	38725	884	79704769
Therapeutic product effect incomplete	21.75	19.11	22	38713	141623	79564030
Substance-induced mood disorder	21.62	19.11	6	38729	119	79705534
Stress	21.51	19.11	6	38729	79606	79626047
Drug diversion	21.47	19.11	11	38724	1239	79704414
Blood pressure increased	21.43	19.11	44	38691	211316	79494337
Gastrooesophageal reflux disease	21.38	19.11	12	38723	104234	79601419
Hypotension	21.36	19.11	316	38419	440001	79265652
Pupil fixed	21.31	19.11	16	38719	3550	79702103
Acidosis	21.19	19.11	36	38699	19726	79685927
Hypertension	21.04	19.11	86	38649	330906	79374747
Dyspnoea exertional	20.99	19.11	8	38727	87065	79618588
Areflexia	20.85	19.11	19	38716	5515	79700138
Behavioural addiction	20.75	19.11	5	38730	55	79705598
Aspiration	20.67	19.11	36	38699	20122	79685531
Analgesic drug level increased	20.65	19.11	15	38720	3163	79702490
Brain death	20.43	19.11	19	38716	5658	79699995
Liver disorder	20.43	19.11	5	38730	72412	79633241
Blood pressure systolic increased	20.16	19.11	4	38731	66982	79638671
Rectal haemorrhage	20.15	19.11	6	38729	76294	79629359
Rash pruritic	20.11	19.11	5	38730	71624	79634029
Gastrointestinal disorder	19.90	19.11	18	38717	122187	79583466
Duodenal ulcer perforation	19.83	19.11	4	38731	66207	79639446
Psychiatric disorder prophylaxis	19.78	19.11	5	38730	68	79705585
Pneumonitis	19.71	19.11	3	38732	60857	79644796
Blood cholesterol increased	19.67	19.11	8	38727	83712	79621941
Gastrointestinal haemorrhage	19.39	19.11	26	38709	147693	79557960
Product use in unapproved indication	19.27	19.11	60	38675	250299	79455354
Rheumatoid factor positive	19.26	19.11	3	38732	59836	79645817
Gun shot wound	19.25	19.11	10	38725	1160	79704493

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	D08AJ08	DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Quaternary ammonium compounds
ATC	D08AJ58	DERMATOLOGICALS ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS Quaternary ammonium compounds
ATC	R02AA09	RESPIRATORY SYSTEM THROAT PREPARATIONS THROAT PREPARATIONS Antiseptics
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000891	Anti-Infective Agents, Local
CHEBI has role	CHEBI:22587	antiviral agents
CHEBI has role	CHEBI:33282	bactericides
CHEBI has role	CHEBI:35718	antifungal agents
CHEBI has role	CHEBI:48218	antiseptics
CHEBI has role	CHEBI:48219	disinfectants

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Skin irritation	indication	367466007
Itching of skin	indication	418363000
Minor Skin Wound Pain	indication
Prevent Minor Bacterial Skin Infection	indication
Bacterial septicemia	contraindication	10001005	DOID:0040085
Shock	contraindication	27942005
Conduction disorder of the heart	contraindication	44808001
Bleeding hemorrhoids	contraindication	51551000
Decreased respiratory function	contraindication	80954004
Disorder of mucous membrane	contraindication	95351003
Open wound	contraindication	125643001
Seizure disorder	contraindication	128613002
Heart block	contraindication	233916004
Disease of liver	contraindication	235856003	DOID:409
Denuded skin	contraindication	418242004

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Type	Activity value (-log[M])	Bioact source
Alpha-2A adrenergic receptor	GPCR	P08913	ADA2A_HUMAN	Ki	5.93	DRUG MATRIX
Potassium voltage-gated channel subfamily H member 2	Ion channel	Q12809	KCNH2_HUMAN	Ki	7.05	DRUG MATRIX
Sodium-dependent serotonin transporter	Transporter	P31645	SC6A4_HUMAN	Ki	5.89	DRUG MATRIX
Sodium-dependent noradrenaline transporter	Transporter	P23975	SC6A2_HUMAN	Ki	6.05	DRUG MATRIX
5-hydroxytryptamine receptor 2A	GPCR	P28223	5HT2A_HUMAN	Ki	7.43	DRUG MATRIX
5-hydroxytryptamine receptor 2C	GPCR	P28335	5HT2C_HUMAN	Ki	6.27	DRUG MATRIX
Alpha-2B adrenergic receptor	GPCR	P18089	ADA2B_HUMAN	Ki	6.53	DRUG MATRIX
Muscarinic acetylcholine receptor M1	GPCR	P11229	ACM1_HUMAN	Ki	7.00	DRUG MATRIX
Muscarinic acetylcholine receptor M2	GPCR	P08172	ACM2_HUMAN	Ki	6.69	DRUG MATRIX
Muscarinic acetylcholine receptor M3	GPCR	P20309	ACM3_HUMAN	Ki	7.09	DRUG MATRIX
Muscarinic acetylcholine receptor M4	GPCR	P08173	ACM4_HUMAN	Ki	7.44	DRUG MATRIX
Muscarinic acetylcholine receptor M5	GPCR	P08912	ACM5_HUMAN	Ki	7.02	DRUG MATRIX
Alpha-2C adrenergic receptor	GPCR	P18825	ADA2C_HUMAN	Ki	6.55	DRUG MATRIX
Sodium-dependent dopamine transporter	Transporter	Q01959	SC6A3_HUMAN	Ki	5.97	DRUG MATRIX
Acetylcholinesterase	Enzyme	P22303	ACES_HUMAN	IC50	5.65	DRUG MATRIX
Tyrosine-protein kinase Fyn	Kinase	P06241	FYN_HUMAN	IC50	6.12	DRUG MATRIX
Receptor tyrosine-protein kinase erbB-2	Kinase	P04626	ERBB2_HUMAN	IC50	5.68	DRUG MATRIX
Substance-K receptor	GPCR	P21452	NK2R_HUMAN	Ki	6.19	DRUG MATRIX
KiSS-1 receptor	GPCR	Q969F8	KISSR_HUMAN	Ki	5.44	CHEMBL
Membrane-associated progesterone receptor component 1	Membrane receptor		PGRC1_RAT	Ki	7.16	DRUG MATRIX

External reference:

ID	Source
N0000005872	NUI
D01140	KEGG_DRUG
4018649	VANDF
C0005041	UMLSCUI
CHEBI:94725	CHEBI
CHEMBL1182210	ChEMBL_ID
CHEMBL221753	ChEMBL_ID
D001558	MESH_DESCRIPTOR_UI
DB11125	DRUGBANK_ID
2335	PUBCHEM_CID
1VU15B70BP	UNII
1390	RXNORM
11805	MMSL
NOCODE	MMSL
003142	NDDF
126147005	SNOMEDCT_US
34929006	SNOMEDCT_US
373482005	SNOMEDCT_US
1170	INN_ID
10172-60-8	SECONDARY_CAS_RN

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Benzethonium chloride and Dyclonine hydrochloride	HUMAN OTC DRUG LABEL	2	0363-0210	LIQUID	0.06 mg	TOPICAL	OTC monograph not final	15 sections
Benzethonium chloride and Dyclonine hydrochloride	HUMAN OTC DRUG LABEL	2	0363-0210	LIQUID	0.06 mg	TOPICAL	OTC monograph not final	15 sections
Walgreens Antiseptic Wound Wash	HUMAN OTC DRUG LABEL	1	0363-1507	SOLUTION	1.30 mg	TOPICAL	OTC monograph not final	14 sections
Pyrocaine Burn	HUMAN OTC DRUG LABEL	2	0498-0010	AEROSOL, SPRAY	0.20 g	TOPICAL	OTC monograph not final	11 sections
Pyrocaine Burn	HUMAN OTC DRUG LABEL	2	0498-0010	AEROSOL, SPRAY	0.20 g	TOPICAL	OTC monograph not final	11 sections
Pyrocaine Burn	HUMAN OTC DRUG LABEL	2	0498-0011	AEROSOL, SPRAY	0.20 g	TOPICAL	OTC monograph not final	11 sections
Pyrocaine Burn	HUMAN OTC DRUG LABEL	2	0498-0011	AEROSOL, SPRAY	0.20 g	TOPICAL	OTC monograph not final	11 sections
North First Aid Antiseptic	HUMAN OTC DRUG LABEL	2	0498-0015	SPRAY	0.20 g	TOPICAL	OTC monograph not final	11 sections
North Burn	HUMAN OTC DRUG LABEL	3	0498-0020	SPRAY	0.20 g	TOPICAL	OTC monograph not final	12 sections
North Burn	HUMAN OTC DRUG LABEL	3	0498-0020	SPRAY	0.20 g	TOPICAL	OTC monograph not final	12 sections
Burn Water Soluble	HUMAN OTC DRUG LABEL	3	0498-0021	SPRAY	0.20 g	TOPICAL	OTC monograph not final	12 sections
Burn Water Soluble	HUMAN OTC DRUG LABEL	3	0498-0021	SPRAY	0.20 g	TOPICAL	OTC monograph not final	12 sections
North First Aid Antiseptic Water Soluble	HUMAN OTC DRUG LABEL	2	0498-0030	SPRAY	0.20 g	TOPICAL	OTC monograph not final	13 sections
North First Aid Antiseptic Water Soluble	HUMAN OTC DRUG LABEL	2	0498-0030	SPRAY	0.20 g	TOPICAL	OTC monograph not final	13 sections
First Aid Antiseptic Water Soluble	HUMAN OTC DRUG LABEL	2	0498-0031	SPRAY	0.20 g	TOPICAL	OTC monograph not final	13 sections
First Aid Antiseptic Water Soluble	HUMAN OTC DRUG LABEL	2	0498-0031	SPRAY	0.20 g	TOPICAL	OTC monograph not final	13 sections
Simply Saline Plus Wound WashAntibacterial First Aid Antiseptic	HUMAN OTC DRUG LABEL	1	10237-694	SPRAY	0.13 mL	TOPICAL	OTC monograph not final	10 sections
Simply SalineWound Care	HUMAN OTC DRUG LABEL	1	10237-700	SPRAY	1 mg	TOPICAL	OTC monograph not final	11 sections
Moisturizing Hand Sanitizer	HUMAN OTC DRUG LABEL	1	11344-478	LOTION	1.98 mg	TOPICAL	OTC monograph not final	10 sections
Moisturizing Hand Sanitizer	HUMAN OTC DRUG LABEL	1	11344-478	LOTION	1.98 mg	TOPICAL	OTC monograph not final	10 sections
Benzethonium chloride Plus Dyclonine hydrochloride	HUMAN OTC DRUG LABEL	2	11673-629	LIQUID	0.20 mg	TOPICAL	OTC monograph not final	15 sections
Benzethonium chloride Plus Dyclonine hydrochloride	HUMAN OTC DRUG LABEL	2	11673-629	LIQUID	0.20 mg	TOPICAL	OTC monograph not final	15 sections
Bedside-Care	HUMAN OTC DRUG LABEL	1	11701-020	SHAMPOO	1 mL	TOPICAL	OTC monograph not final	10 sections
Bedside-Care Foam (Alcohol Free)	HUMAN OTC DRUG LABEL	1	11701-052	SHAMPOO	100 mg	TOPICAL	OTC monograph not final	10 sections
Bedside-Care	HUMAN OTC DRUG LABEL	1	11701-053	SHAMPOO	100 mg	TOPICAL	OTC monograph not final	10 sections
Bedside-Care Perineal Wash	HUMAN OTC DRUG LABEL	1	11701-059	LIQUID	1 mL	TOPICAL	OTC monograph not final	10 sections
Benzethonium chloride Plus Dyclonine hydrochloride	HUMAN OTC DRUG LABEL	2	11822-0128	LIQUID	0.20 mg	TOPICAL	OTC monograph not final	15 sections
Benzethonium chloride Plus Dyclonine hydrochloride	HUMAN OTC DRUG LABEL	2	11822-0128	LIQUID	0.20 mg	TOPICAL	OTC monograph not final	15 sections
Benzethonium Chloride and Dyclonine Hydrochloride	HUMAN OTC DRUG LABEL	2	11822-0779	LIQUID	0.20 mg	TOPICAL	OTC monograph not final	15 sections
3 in 1 First Aid Wound Care	HUMAN OTC DRUG LABEL	1	11822-5074	SOLUTION	1.30 mg	TOPICAL	OTC monograph not final	14 sections