bemotrizinol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3014 187393-00-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bemotrizinol
  • Tinosorb S
  • Molecular weight: 627.83
  • Formula: C38H49N3O5
  • CLOGP: 10.98
  • LIPINSKI: 2
  • HAC: 8
  • HDO: 2
  • TPSA: 106.82
  • ALOGS: -6.27
  • ROTB: 18

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AKT2,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK1,JAK2,MAP2K6,MAP3K1,MAP3K21,MAP3K7,MAP4K1,MAPK10,MAPK7,MAPK9,MAPKAPK2,MARK4,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1 56
kinase-selectivity-class BRAF,PDK4,PIK3CA 3
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Sunscreen agent indication 49663007




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.95 acidic
pKa2 9.55 acidic
pKa3 2.33 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D03227 KEGG_DRUG
C2698346 UMLSCUI
CHEBI:135857 CHEBI
CHEMBL2104956 ChEMBL_ID
DB11206 DRUGBANK_ID
C439083 MESH_SUPPLEMENTAL_RECORD_UI
8585 INN_ID
PWZ1720CBH UNII
135487856 PUBCHEM_CID
1306115 RXNORM
015431 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Homme Aqua Sun Block SPF50 Plus PA 2Plus HUMAN OTC DRUG LABEL 5 49715-013 CREAM 1.31 g TOPICAL OTC monograph final 10 sections
Garnier Ombrelle Daily UV 60 Antidry Moisturizer Sunscreen HUMAN OTC DRUG LABEL 7 49967-042 LOTION 50 mg TOPICAL export only 5 sections
Garnier Ombrelle Ultra Light Advanced 60 Face Sunscreen HUMAN OTC DRUG LABEL 7 49967-046 LOTION 50 mg TOPICAL export only 5 sections
Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types HUMAN OTC DRUG LABEL 7 49967-123 LOTION 40 mg TOPICAL export only 4 sections
Kiehls Ultra Light Daily UV Defense CC SPF 50 Anti Pollution HUMAN OTC DRUG LABEL 6 49967-161 CREAM 5 mg TOPICAL export only 4 sections
Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types HUMAN OTC DRUG LABEL 7 49967-309 LOTION 40 mg TOPICAL export only 4 sections
KIEHLS DERMATOLOGIST SOLUTIONS ULTRA LIGHT DAILY UV DEFENSE SUNSCREEN SPF 50 HIGH PROTECTION ANTI-POLLUTION LIGHTWEIGHT FORMULA FOR ALL SKIN TYPES HUMAN OTC DRUG LABEL 6 49967-449 LOTION 5 mg TOPICAL export only 4 sections
Garnier Ombrelle Ultra Light Advanced Broad Spectrum SPF 60 Sunscreen HUMAN OTC DRUG LABEL 7 49967-649 LOTION 50 mg TOPICAL export only 11 sections
THE HISTORY OF WHOO GONG JIN HYANG HAE YOON SUN HUMAN OTC DRUG LABEL 2 53208-452 CREAM 0.80 mL TOPICAL OTC monograph not final 6 sections
OHUI Sun Science intensive sunblock cake EX HUMAN OTC DRUG LABEL 4 53208-473 CREAM 1.50 g TOPICAL OTC monograph not final 6 sections
The History of Whoo Jin Hae Yoon Sun HUMAN OTC DRUG LABEL 5 53208-503 CREAM 1 mL TOPICAL OTC monograph not final 5 sections
OHUI SUNSCIENCE LUMINOUS WHITENING SUNBLOCK HUMAN OTC DRUG LABEL 8 53208-518 CREAM 1.50 mL TOPICAL OTC monograph not final 5 sections
OHUI SUN SCIENCE Perfect Sunblock Blue EX plus HUMAN OTC DRUG LABEL 5 53208-539 CREAM 2 mL TOPICAL OTC monograph not final 6 sections
SOORYEHAN HYO FERMENTED SUN BLOCK HUMAN OTC DRUG LABEL 7 53208-549 CREAM 1 mL TOPICAL OTC monograph not final 7 sections
LAPOTHICELL Sunscreen HUMAN OTC DRUG LABEL 6 58832-0005 CREAM 1.75 g TOPICAL OTC monograph not final 7 sections
SPA SKILHA HELIOPROT AB SPF 40 HUMAN OTC DRUG LABEL 4 66854-025 CREAM 1.50 g TOPICAL OTC monograph final 8 sections
DPC PINK AURA CUSHION NO.21 HUMAN OTC DRUG LABEL 5 71673-0007 LIQUID 1.50 g TOPICAL OTC monograph not final 7 sections
DPC PINK AURA CUSHION NO.23 HUMAN OTC DRUG LABEL 5 71673-0008 LIQUID 1.50 g TOPICAL OTC monograph not final 7 sections
CELGEN MILD SUN HUMAN OTC DRUG LABEL 6 76731-204 CREAM 4 g TOPICAL OTC monograph not final 9 sections
Codenature Viami Tone Up Shield Cream HUMAN OTC DRUG LABEL 3 78625-201 CREAM 2500 mg TOPICAL OTC monograph not final 12 sections
AnubisMed HUMAN OTC DRUG LABEL 28 83021-551 CREAM 1.45 g TOPICAL OTC monograph final 7 sections
Anubis Barcelona Protective Line HUMAN OTC DRUG LABEL 27 83021-686 CREAM 1.45 g TOPICAL OTC monograph final 9 sections
Dr.Jucre Rebirth White Sun Protection HUMAN OTC DRUG LABEL 9 83071-060 CREAM 1.50 g TOPICAL unapproved drug other 10 sections
Dr.Jucre Rebirth Sun Protection HUMAN OTC DRUG LABEL 9 83071-150 CREAM 1.50 g TOPICAL unapproved drug other 10 sections
P.CALM Water Barrier Suncream HUMAN OTC DRUG LABEL 5 83735-001 CREAM 5 mg TOPICAL unapproved drug other 7 sections
CraTiv Sunscreen HUMAN OTC DRUG LABEL 9 84301-001 LOTION 2 g TOPICAL OTC Monograph Drug 11 sections
Beauty Body Factorie Body Shield SPF HUMAN OTC DRUG LABEL 5 84755-0006 LOTION 30 mg TOPICAL unapproved drug other 8 sections
Beauty Body Factorie Body Shield SPF HUMAN OTC DRUG LABEL 5 84755-0006 LOTION 30 mg TOPICAL unapproved drug other 8 sections
MENOW SUNSCREEN HUMAN OTC DRUG LABEL 4 85138-101 POWDER 0.77 g CUTANEOUS unapproved drug other 9 sections
Centella Sunscreen SPF 50 HUMAN OTC DRUG LABEL 5 85473-442 CREAM 1.50 g CUTANEOUS OTC Monograph Drug 7 sections