DrugCentral 2023 ๐
2022 Update-Veterinary Drugs & Uses
Search
Structure ๐
Similarity ๐
Smart API
Redial
About
Download
L1000
FAQ
DrugCentral 2023 ๐
2022 Update-Veterinary Drugs & Uses
Search
Structure ๐
Similarity ๐
Smart API
Redial
About
Download
L1000
FAQ
Scroll
All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
pyrantel ๐ถ
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
anthelminthics (undefined group)
2999
15686-83-6
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
pyrantel
pyrequan
pyrantel pamoate
pyrantel tartrate
Broad spectrum anthelmintic for livestock.
Molecular weight: 206.31
Formula: C11H14N2S
CLOGP: 3.03
LIPINSKI: 0
HAC: 2
HDO: 0
TPSA: 15.60
ALOGS: -3.24
ROTB: 2
Drug dosage:
Dose
Unit
Route
0.75
g
O
ADMET properties:
Show
10
25
50
100
entries
Search:
Property
Value
Reference
EoM (Fraction excreted unchanged in urine)
7 %
Benet LZ, Broccatelli F, Oprea TI
MRTD (Maximum Recommended Therapeutic Daily Dose)
55.08 ยตM/kg/day
Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
BDDCS (Biopharmaceutical Drug Disposition Classification System)
2
Benet LZ, Broccatelli F, Oprea TI
S (Water solubility)
0.50 mg/mL
Benet LZ, Broccatelli F, Oprea TI
Showing 1 to 4 of 4 entries
Previous
1
Next
Approvals:
Show
10
25
50
100
entries
Search:
Date
Agency
Company
Orphan
Jan. 1, 1974
YEAR INTRODUCED
Showing 1 to 1 of 1 entries
Previous
1
Next
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
Show
10
25
50
100
entries
Search:
Source
Code
Description
ATC
P02CC01
ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTHELMINTICS
ANTINEMATODAL AGENTS
Tetrahydropyrimidine derivatives
CHEBI has role
CHEBI:35444
antinematodal drugs
MeSH PA
D000871
Anthelmintics
MeSH PA
D000890
Anti-Infective Agents
MeSH PA
D000969
Antinematodal Agents
MeSH PA
D000977
Antiparasitic Agents
MeSH PA
D009465
Neuromuscular Agents
MeSH PA
D009466
Neuromuscular Blocking Agents
MeSH PA
D009467
Neuromuscular Depolarizing Agents
MeSH PA
D018373
Peripheral Nervous System Agents
Showing 1 to 10 of 10 entries
Previous
1
Next
Drug Use
| Suggest Off label Use Form|
|View source of the data|
Show
10
25
50
100
entries
Search:
Disease
Relation
SNOMED_ID
DOID
Ascariasis
indication
2435008
DOID:456
Mixed intestinal infection due to Class Cestoda and/or Class Trematoda and/or Phylum Nemata
indication
90679001
Enterobiasis
indication
266162007
Infection by Moniliformis
off-label use
2341000
Trichostrongyliasis
off-label use
33710003
DOID:1254
Infection by Uncinaria
off-label use
414490001
Necator Americanus Infection
off-label use
Ancylostoma Duodenale Infection
off-label use
Disease of liver
contraindication
235856003
DOID:409
Showing 1 to 9 of 9 entries
Previous
1
Next
๐ถ Veterinary Drug Use
Show
10
25
50
100
entries
Search:
Species
Use
Relation
Dogs
Removal and control of large roundworms, Toxocara canis
Indication
Dogs
Removal and control of large roundworms, Toxascaris leonin
Indication
Dogs
Removal and control of hookworms, Ancylostoma caninum
Indication
Dogs
Removal and control of hookworms, Uncinaria stenocephala
Indication
Horses
Removal of large strongyles, Strongylus vulgaris
Indication
Horses
Removal of large strongyles, Strongylus edentatus
Indication
Horses
Removal of large strongyles, Strongylus equinus
Indication
Horses
Removal of pinworms, Oxyuris equi
Indication
Horses
Removal of large roundworms, Parascaris
Indication
Swine
Removal and control of large roundworm, Ascaris suum
Indication
Showing 1 to 10 of 14 entries
Previous
1
2
Next
๐ถ Veterinary products
Show
10
25
50
100
entries
Search:
Product
Applicant
Ingredients
Adams, D-Worm, Dog Wormer Chewable Tablets
Farnam Companies Inc.
1
Anthelban V
Elanco US Inc.
1
Ban-A-Worm Py. Tartrate, Ban-A-Worm Pyrantel Tartrate Ton Pack
ADM Animal Nutrition
1
Banminth / Mecadox
Phibro Animal Health Corp.
2
Banminth 48
Phibro Animal Health Corp.
1
Banminth, Strongid
Zoetis Inc.
1
Banminth-P Paste, Strongid Paste
Zoetis Inc.
1
Continuex
Farnam Companies Inc.
1
Dog Wormer Tablets
Farnam Companies Inc.
1
Drontal Plus, Drontal Plus Taste Tabs, Quad Dewormer
Elanco US Inc.
3
Showing 1 to 10 of 34 entries
Previous
1
2
3
4
Next
Acid dissociation constants calculated using MoKa v3.0.0
Show
10
25
50
100
entries
Search:
Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
9.98
Basic
Showing 1 to 1 of 1 entries
Previous
1
Next
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
Show
10
25
50
100
entries
Search:
Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Acetylcholinesterase
Enzyme
O96529_MELIC
WOMBAT-PK
Showing 1 to 1 of 1 entries
Previous
1
Next
External reference:
Show
10
25
50
100
entries
Search:
ID
Source
002986
NDDF
004115
NDDF
2197593
RXNORM
22204-24-6
SECONDARY_CAS_RN
2228
INN_ID
25013003
SNOMEDCT_US
33401-94-4
SECONDARY_CAS_RN
36068003
SNOMEDCT_US
387193008
SNOMEDCT_US
4019104
VANDF
Showing 1 to 10 of 30 entries
Previous
1
2
3
Next
Pharmaceutical products:
Show
10
25
50
100
entries
Search:
Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
CVS Pinworm Treatment
HUMAN OTC DRUG LABEL
1
69842-618
SUSPENSION
144 mg
ORAL
OTC monograph final
10 sections
CVS Pinworm Treatment
HUMAN OTC DRUG LABEL
1
69842-618
SUSPENSION
144 mg
ORAL
OTC monograph final
10 sections
Parasitexx
HUMAN OTC DRUG LABEL
1
70242-134
SUSPENSION
144 mg
ORAL
OTC monograph final
12 sections
PARASITOL
HUMAN OTC DRUG LABEL
1
53145-101
SUSPENSION
144 mg
ORAL
OTC monograph final
9 sections
PARASITOL
HUMAN OTC DRUG LABEL
1
53145-306
TABLET
180 mg
ORAL
OTC monograph final
12 sections
PinAway
HUMAN OTC DRUG LABEL
1
0295-1062
SUSPENSION
144 mg
ORAL
OTC monograph final
13 sections
PinAway
HUMAN OTC DRUG LABEL
1
70309-080
SUSPENSION
144 mg
ORAL
OTC monograph final
13 sections
PINRID
HUMAN OTC DRUG LABEL
1
73581-107
TABLET
250 mg
ORAL
OTC monograph final
10 sections
Pinworm Medicine
HUMAN OTC DRUG LABEL
1
10956-618
SUSPENSION
144 mg
ORAL
OTC monograph final
10 sections
Pinworm Treatment
HUMAN OTC DRUG LABEL
1
59779-538
SUSPENSION
144 mg
ORAL
OTC monograph final
13 sections
Showing 1 to 10 of 25 entries
Previous
1
2
3
Next
Search
Structure ๐
Similarity ๐
Smart API
Redial
About
Download
L1000
FAQ
pyrantel