suramin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2966 145-63-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • suramin
  • metaret
  • naganol
  • suramine
  • suramin sodium
  • suramin hexasodium
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.
  • Molecular weight: 1297.26
  • Formula: C51H40N6O23S6
  • CLOGP: -8.58
  • LIPINSKI: 3
  • HAC: 29
  • HDO: 12
  • TPSA: 483.75
  • ALOGS: -5.17
  • ROTB: 16

Drug dosage:

DoseUnitRoute
0.27 g P

ADMET properties:

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

suramin