viomycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antibiotics, produced by Streptomyces strains | 2830 | 32988-50-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A strongly basic peptide, antibiotic complex from several strains of Streptomyces. It is allergenic and toxic to kidneys and the labyrinth. Viomycin is used in tuberculosis as several different salts and in combination with other agents.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA | PFIZER |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| CHEBI has role | CHEBI:33231 | antitubercular agents |
| MeSH PA | D000900 | Anti-Bacterial Agents |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000904 | Antibiotics, Antitubercular |
| MeSH PA | D000995 | Antitubercular Agents |
| MeSH PA | D004791 | Enzyme Inhibitors |
| MeSH PA | D011500 | Protein Synthesis Inhibitors |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 10.53 | acidic |
| pKa2 | 12.11 | acidic |
| pKa3 | 12.74 | acidic |
| pKa4 | 13.0 | acidic |
| pKa5 | 13.35 | acidic |
| pKa6 | 13.69 | acidic |
| pKa7 | 13.92 | acidic |
| pKa8 | 11.06 | Basic |
| pKa9 | 10.06 | Basic |
| pKa10 | 7.7 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D02270 | KEGG_DRUG |
| C0042697 | UMLSCUI |
| CHEBI:15782 | CHEBI |
| CHEMBL3085436 | ChEMBL_ID |
| D014756 | MESH_DESCRIPTOR_UI |
| DB06827 | DRUGBANK_ID |
| 283 | INN_ID |
| 37883-00-4 | SECONDARY_CAS_RN |
| YVU35998K5 | UNII |
| 135398671 | PUBCHEM_CID |
| 002773 | NDDF |
| 002774 | NDDF |
| 19967004 | SNOMEDCT_US |
| CHEMBL3989823 | ChEMBL_ID |
Pharmaceutical products:
None