Malignant neoplasm progression |
902.70 |
17.55 |
486 |
21071 |
64440 |
46600065 |
Disease progression |
692.80 |
17.55 |
463 |
21094 |
90837 |
46573668 |
Metastases to liver |
527.72 |
17.55 |
231 |
21326 |
19354 |
46645151 |
Metastases to bone |
476.89 |
17.55 |
208 |
21349 |
17268 |
46647237 |
Neutropenia |
446.18 |
17.55 |
431 |
21126 |
142773 |
46521732 |
Palmar-plantar erythrodysaesthesia syndrome |
402.62 |
17.55 |
194 |
21363 |
20257 |
46644248 |
Breast cancer metastatic |
344.69 |
17.55 |
154 |
21403 |
13524 |
46650981 |
Metastases to lung |
264.90 |
17.55 |
119 |
21438 |
10577 |
46653928 |
Metastases to central nervous system |
216.35 |
17.55 |
105 |
21452 |
11116 |
46653389 |
Metastases to lymph nodes |
214.13 |
17.55 |
89 |
21468 |
6542 |
46657963 |
Breast cancer |
196.50 |
17.55 |
165 |
21392 |
45353 |
46619152 |
Osteonecrosis |
193.18 |
17.55 |
130 |
21427 |
25614 |
46638891 |
Febrile neutropenia |
189.86 |
17.55 |
226 |
21331 |
94401 |
46570104 |
Mucosal inflammation |
180.12 |
17.55 |
147 |
21410 |
38829 |
46625676 |
Osteonecrosis of jaw |
176.57 |
17.55 |
138 |
21419 |
34264 |
46630241 |
Neoplasm progression |
165.74 |
17.55 |
120 |
21437 |
26563 |
46637942 |
Haematotoxicity |
146.17 |
17.55 |
69 |
21488 |
6864 |
46657641 |
Pseudocirrhosis |
129.92 |
17.55 |
35 |
21522 |
653 |
46663852 |
Ejection fraction decreased |
128.39 |
17.55 |
88 |
21469 |
17849 |
46646656 |
Neuropathy peripheral |
111.57 |
17.55 |
171 |
21386 |
90722 |
46573783 |
Breast cancer recurrent |
111.30 |
17.55 |
48 |
21509 |
3863 |
46660642 |
Pleural effusion |
110.28 |
17.55 |
162 |
21395 |
82790 |
46581715 |
Metastases to skin |
109.90 |
17.55 |
36 |
21521 |
1344 |
46663161 |
Metastases to peritoneum |
104.27 |
17.55 |
41 |
21516 |
2607 |
46661898 |
Bone marrow failure |
93.26 |
17.55 |
90 |
21467 |
29579 |
46634926 |
Neutropenic sepsis |
87.09 |
17.55 |
60 |
21497 |
12264 |
46652241 |
Fall |
84.05 |
17.55 |
24 |
21533 |
329073 |
46335432 |
Drug hypersensitivity |
81.10 |
17.55 |
9 |
21548 |
243816 |
46420689 |
PIK3CA-activated mutation |
78.89 |
17.55 |
23 |
21534 |
578 |
46663927 |
Ascites |
77.58 |
17.55 |
90 |
21467 |
36494 |
46628011 |
Tooth extraction |
72.91 |
17.55 |
50 |
21507 |
10143 |
46654362 |
Lymphoedema |
70.64 |
17.55 |
46 |
21511 |
8566 |
46655939 |
Leukopenia |
68.04 |
17.55 |
117 |
21440 |
68226 |
46596279 |
Neurotoxicity |
65.98 |
17.55 |
53 |
21504 |
13664 |
46650841 |
Product dose omission issue |
65.18 |
17.55 |
3 |
21554 |
168517 |
46495988 |
Tonsillar disorder |
56.72 |
17.55 |
20 |
21537 |
936 |
46663569 |
Bone disorder |
54.14 |
17.55 |
56 |
21501 |
19977 |
46644528 |
Debridement |
53.49 |
17.55 |
21 |
21536 |
1329 |
46663176 |
Thrombocytopenia |
49.07 |
17.55 |
149 |
21408 |
126432 |
46538073 |
Metastases to spine |
48.29 |
17.55 |
24 |
21533 |
2670 |
46661835 |
Polyneuropathy |
47.70 |
17.55 |
41 |
21516 |
11603 |
46652902 |
Therapy partial responder |
45.89 |
17.55 |
28 |
21529 |
4654 |
46659851 |
Lymphangiosis carcinomatosa |
45.75 |
17.55 |
18 |
21539 |
1146 |
46663359 |
Metastasis |
45.40 |
17.55 |
27 |
21530 |
4285 |
46660220 |
Jaw operation |
44.77 |
17.55 |
16 |
21541 |
779 |
46663726 |
Vessel puncture site bruise |
44.54 |
17.55 |
13 |
21544 |
328 |
46664177 |
Skin toxicity |
44.10 |
17.55 |
25 |
21532 |
3629 |
46660876 |
Death |
44.03 |
17.55 |
285 |
21272 |
335263 |
46329242 |
Blood uric acid decreased |
42.85 |
17.55 |
14 |
21543 |
518 |
46663987 |
Joint swelling |
42.52 |
17.55 |
12 |
21545 |
166061 |
46498444 |
Stomatitis |
42.50 |
17.55 |
96 |
21461 |
68201 |
46596304 |
Nasal disorder |
40.50 |
17.55 |
20 |
21537 |
2194 |
46662311 |
Metastases to chest wall |
40.32 |
17.55 |
13 |
21544 |
461 |
46664044 |
Sequestrectomy |
40.24 |
17.55 |
16 |
21541 |
1047 |
46663458 |
Peripheral sensory neuropathy |
39.39 |
17.55 |
29 |
21528 |
6574 |
46657931 |
Arthralgia |
38.94 |
17.55 |
68 |
21489 |
364535 |
46299970 |
Cardiotoxicity |
38.92 |
17.55 |
29 |
21528 |
6693 |
46657812 |
Urticaria |
37.56 |
17.55 |
5 |
21552 |
117887 |
46546618 |
Tumour marker increased |
36.83 |
17.55 |
22 |
21535 |
3519 |
46660986 |
Pruritus |
36.36 |
17.55 |
35 |
21522 |
242317 |
46422188 |
Metastases to pleura |
36.35 |
17.55 |
15 |
21542 |
1081 |
46663424 |
Eosinophil percentage increased |
36.23 |
17.55 |
14 |
21543 |
849 |
46663656 |
Drug ineffective |
36.11 |
17.55 |
176 |
21381 |
677662 |
45986843 |
Hypothalamo-pituitary disorder |
35.72 |
17.55 |
13 |
21544 |
667 |
46663838 |
Gastrointestinal toxicity |
35.19 |
17.55 |
23 |
21534 |
4308 |
46660197 |
Second primary malignancy |
35.02 |
17.55 |
27 |
21530 |
6557 |
46657948 |
Metastases to soft tissue |
34.47 |
17.55 |
9 |
21548 |
148 |
46664357 |
EGFR gene mutation |
34.41 |
17.55 |
9 |
21548 |
149 |
46664356 |
Desmoplastic small round cell tumour |
34.30 |
17.55 |
9 |
21548 |
151 |
46664354 |
Metastases to meninges |
34.05 |
17.55 |
17 |
21540 |
1910 |
46662595 |
Superior vena cava syndrome |
33.80 |
17.55 |
12 |
21545 |
573 |
46663932 |
Axillary pain |
33.74 |
17.55 |
15 |
21542 |
1298 |
46663207 |
Off label use |
33.59 |
17.55 |
294 |
21263 |
379547 |
46284958 |
Myelosuppression |
33.34 |
17.55 |
28 |
21529 |
7675 |
46656830 |
Injection site pain |
33.06 |
17.55 |
5 |
21552 |
107147 |
46557358 |
Osteomyelitis |
33.05 |
17.55 |
46 |
21511 |
22337 |
46642168 |
Pyrexia |
32.42 |
17.55 |
273 |
21284 |
348529 |
46315976 |
Somnolence |
32.22 |
17.55 |
16 |
21541 |
156505 |
46508000 |
Invasive ductal breast carcinoma |
32.17 |
17.55 |
25 |
21532 |
6143 |
46658362 |
Anaemia |
32.12 |
17.55 |
215 |
21342 |
255564 |
46408941 |
Sinusitis |
32.07 |
17.55 |
10 |
21547 |
129758 |
46534747 |
Portal hypertension |
32.03 |
17.55 |
20 |
21537 |
3463 |
46661042 |
Pituitary tumour |
31.97 |
17.55 |
13 |
21544 |
902 |
46663603 |
Metastatic neoplasm |
31.46 |
17.55 |
20 |
21537 |
3573 |
46660932 |
Asthma |
31.37 |
17.55 |
3 |
21554 |
91539 |
46572966 |
Loss of consciousness |
31.30 |
17.55 |
6 |
21551 |
108232 |
46556273 |
Maternal exposure during pregnancy |
31.15 |
17.55 |
5 |
21552 |
102544 |
46561961 |
Disease recurrence |
30.37 |
17.55 |
40 |
21517 |
18431 |
46646074 |
General physical health deterioration |
29.79 |
17.55 |
119 |
21438 |
115650 |
46548855 |
Drug interaction |
29.68 |
17.55 |
30 |
21527 |
203064 |
46461441 |
Urinary tract infection |
29.47 |
17.55 |
35 |
21522 |
220231 |
46444274 |
Neutrophil count decreased |
29.22 |
17.55 |
63 |
21494 |
43363 |
46621142 |
Transaminases |
29.17 |
17.55 |
7 |
21550 |
80 |
46664425 |
Decreased appetite |
28.71 |
17.55 |
170 |
21387 |
193666 |
46470839 |
Condition aggravated |
28.66 |
17.55 |
43 |
21514 |
245009 |
46419496 |
Blood lactate dehydrogenase increased |
28.59 |
17.55 |
41 |
21516 |
20459 |
46644046 |
Bone lesion |
27.94 |
17.55 |
21 |
21536 |
4910 |
46659595 |
Pneumonitis |
27.40 |
17.55 |
48 |
21509 |
28372 |
46636133 |
Dermatitis exfoliative generalised |
26.95 |
17.55 |
17 |
21540 |
2996 |
46661509 |
Weight increased |
26.76 |
17.55 |
22 |
21535 |
164451 |
46500054 |
Headache |
26.69 |
17.55 |
122 |
21435 |
478230 |
46186275 |
Osteolysis |
26.58 |
17.55 |
16 |
21541 |
2596 |
46661909 |
Neutropenic infection |
26.07 |
17.55 |
12 |
21545 |
1126 |
46663379 |
Constipation |
25.98 |
17.55 |
153 |
21404 |
173944 |
46490561 |
Calcium ionised increased |
25.62 |
17.55 |
7 |
21550 |
138 |
46664367 |
Hormone receptor positive breast cancer |
25.32 |
17.55 |
9 |
21548 |
431 |
46664074 |
Overdose |
24.94 |
17.55 |
8 |
21549 |
101971 |
46562534 |
Vomiting |
24.71 |
17.55 |
318 |
21239 |
452476 |
46212029 |
Bone sequestrum |
24.48 |
17.55 |
13 |
21544 |
1660 |
46662845 |
Gingivitis |
23.97 |
17.55 |
23 |
21534 |
7497 |
46657008 |
Feeling abnormal |
23.95 |
17.55 |
14 |
21543 |
125046 |
46539459 |
Anal erythema |
23.43 |
17.55 |
7 |
21550 |
192 |
46664313 |
Neoplasm malignant |
23.06 |
17.55 |
40 |
21517 |
23459 |
46641046 |
Memory impairment |
22.98 |
17.55 |
4 |
21553 |
77333 |
46587172 |
Jaw disorder |
22.94 |
17.55 |
19 |
21538 |
5111 |
46659394 |
Asthenia |
22.57 |
17.55 |
231 |
21326 |
310844 |
46353661 |
Hypotension |
22.48 |
17.55 |
46 |
21511 |
232543 |
46431962 |
Ejection fraction abnormal |
22.29 |
17.55 |
9 |
21548 |
613 |
46663892 |
Vascular device infection |
22.23 |
17.55 |
16 |
21541 |
3501 |
46661004 |
Hepatic failure |
21.93 |
17.55 |
48 |
21509 |
33368 |
46631137 |
Jaundice |
21.92 |
17.55 |
44 |
21513 |
28801 |
46635704 |
Injection site erythema |
21.79 |
17.55 |
4 |
21553 |
74423 |
46590082 |
Ileus paralytic |
21.42 |
17.55 |
17 |
21540 |
4306 |
46660199 |
Exposed bone in jaw |
21.21 |
17.55 |
15 |
21542 |
3193 |
46661312 |
Exposure during pregnancy |
20.88 |
17.55 |
12 |
21545 |
108200 |
46556305 |
Cardiac cirrhosis |
20.88 |
17.55 |
6 |
21551 |
143 |
46664362 |
Bone pain |
20.83 |
17.55 |
58 |
21499 |
46832 |
46617673 |
Drug resistance |
20.32 |
17.55 |
32 |
21525 |
17336 |
46647169 |
Abdominal discomfort |
20.23 |
17.55 |
24 |
21533 |
151141 |
46513364 |
Scintillating scotoma |
20.20 |
17.55 |
6 |
21551 |
161 |
46664344 |
Diffuse large B-cell lymphoma recurrent |
20.17 |
17.55 |
11 |
21546 |
1481 |
46663024 |
Blood creatinine decreased |
20.16 |
17.55 |
17 |
21540 |
4687 |
46659818 |
Ectropion |
19.89 |
17.55 |
6 |
21551 |
170 |
46664335 |
Malignant pleural effusion |
19.84 |
17.55 |
13 |
21544 |
2445 |
46662060 |
Acute myeloid leukaemia |
19.76 |
17.55 |
30 |
21527 |
15748 |
46648757 |
Hyperbaric oxygen therapy |
19.70 |
17.55 |
5 |
21552 |
73 |
46664432 |
Joint ankylosis |
19.66 |
17.55 |
8 |
21549 |
556 |
46663949 |
Pancytopenia |
19.18 |
17.55 |
84 |
21473 |
84974 |
46579531 |
Bronchitis |
18.73 |
17.55 |
13 |
21544 |
105966 |
46558539 |
Musculoskeletal stiffness |
18.72 |
17.55 |
11 |
21546 |
97982 |
46566523 |
Primary mediastinal large B-cell lymphoma |
18.55 |
17.55 |
4 |
21553 |
27 |
46664478 |
Recurrent cancer |
18.48 |
17.55 |
11 |
21546 |
1748 |
46662757 |
Hyperplasia |
18.28 |
17.55 |
8 |
21549 |
667 |
46663838 |
Bone marrow infiltration |
18.17 |
17.55 |
7 |
21550 |
421 |
46664084 |
Atrial fibrillation |
17.93 |
17.55 |
13 |
21544 |
103577 |
46560928 |
Sensory disturbance |
17.79 |
17.55 |
25 |
21532 |
12242 |
46652263 |
Metastases to the mediastinum |
17.58 |
17.55 |
7 |
21550 |
460 |
46664045 |