Stem definition | Drug id | CAS RN |
---|---|---|
2813 | 93413-69-5 |
Dose | Unit | Route |
---|---|---|
0.10 | g | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 572 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 4.60 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 11.59 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 45 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 4.40 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 14 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.73 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 5 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 28, 1993 | FDA | WYETH PHARMS INC |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Completed suicide | 1381.53 | 10.00 | 1903 | 176785 | 131930 | 55981449 |
Drug withdrawal syndrome | 1213.64 | 10.00 | 847 | 177841 | 25010 | 56088369 |
Intentional overdose | 1042.94 | 10.00 | 1181 | 177507 | 66936 | 56046443 |
Serotonin syndrome | 866.49 | 10.00 | 699 | 177989 | 25791 | 56087588 |
Suicide attempt | 860.19 | 10.00 | 988 | 177700 | 56848 | 56056531 |
Suicidal ideation | 851.39 | 10.00 | 982 | 177706 | 56760 | 56056619 |
Toxicity to various agents | 750.89 | 10.00 | 1971 | 176717 | 222593 | 55890786 |
Depression | 733.29 | 10.00 | 1705 | 176983 | 178412 | 55934967 |
Overdose | 590.67 | 10.00 | 1140 | 177548 | 104690 | 56008689 |
Rheumatoid arthritis | 556.30 | 10.00 | 260 | 178428 | 382344 | 55731035 |
Intentional self-injury | 552.70 | 10.00 | 528 | 178160 | 24464 | 56088915 |
Drug abuse | 550.93 | 10.00 | 861 | 177827 | 66749 | 56046630 |
Withdrawal syndrome | 489.97 | 10.00 | 432 | 178256 | 18030 | 56095349 |
Drug interaction | 446.60 | 10.00 | 1572 | 177116 | 208183 | 55905196 |
Poisoning deliberate | 443.50 | 10.00 | 316 | 178372 | 9637 | 56103742 |
Anxiety | 411.37 | 10.00 | 1448 | 177240 | 191724 | 55921655 |
Systemic lupus erythematosus | 383.96 | 10.00 | 57 | 178631 | 180021 | 55933358 |
Contraindicated product administered | 372.72 | 10.00 | 70 | 178618 | 186216 | 55927163 |
Synovitis | 370.68 | 10.00 | 40 | 178648 | 161265 | 55952114 |
Hand deformity | 365.55 | 10.00 | 14 | 178674 | 134478 | 55978901 |
Joint swelling | 354.71 | 10.00 | 243 | 178445 | 289557 | 55823822 |
Agitation | 347.71 | 10.00 | 632 | 178056 | 55404 | 56057975 |
Sopor | 335.63 | 10.00 | 372 | 178316 | 20550 | 56092829 |
Coma | 335.45 | 10.00 | 645 | 178043 | 59010 | 56054369 |
Glossodynia | 323.26 | 10.00 | 49 | 178639 | 152409 | 55960970 |
Arthropathy | 295.37 | 10.00 | 133 | 178555 | 200142 | 55913237 |
Tremor | 287.65 | 10.00 | 942 | 177746 | 120147 | 55993232 |
Pericarditis | 284.00 | 10.00 | 15 | 178673 | 108908 | 56004471 |
Mydriasis | 271.87 | 10.00 | 248 | 178440 | 10823 | 56102556 |
Crying | 267.17 | 10.00 | 335 | 178353 | 21105 | 56092274 |
Infusion related reaction | 263.84 | 10.00 | 169 | 178519 | 208762 | 55904617 |
Somnolence | 251.08 | 10.00 | 1106 | 177582 | 162307 | 55951072 |
Wound | 240.38 | 10.00 | 71 | 178617 | 138733 | 55974646 |
Hyperhidrosis | 236.12 | 10.00 | 746 | 177942 | 93342 | 56020037 |
Alopecia | 234.99 | 10.00 | 355 | 178333 | 293103 | 55820276 |
Electrocardiogram QT prolonged | 225.06 | 10.00 | 520 | 178168 | 54068 | 56059311 |
Swelling | 224.71 | 10.00 | 258 | 178430 | 239513 | 55873866 |
Rash | 220.53 | 10.00 | 814 | 177874 | 492233 | 55621146 |
Treatment failure | 212.11 | 10.00 | 140 | 178548 | 170252 | 55943127 |
Abdominal discomfort | 210.97 | 10.00 | 347 | 178341 | 276927 | 55836452 |
Seizure | 208.42 | 10.00 | 868 | 177820 | 124251 | 55989128 |
Hypersensitivity | 202.50 | 10.00 | 313 | 178375 | 256095 | 55857284 |
Helicobacter infection | 197.76 | 10.00 | 8 | 178680 | 73260 | 56040119 |
Discomfort | 188.19 | 10.00 | 108 | 178580 | 141653 | 55971726 |
Akathisia | 180.33 | 10.00 | 177 | 178511 | 8475 | 56104904 |
Irritability | 176.26 | 10.00 | 328 | 178360 | 29260 | 56084119 |
Selective eating disorder | 175.54 | 10.00 | 96 | 178592 | 1808 | 56111571 |
Panic attack | 167.22 | 10.00 | 261 | 178427 | 20186 | 56093193 |
Depressed mood | 166.25 | 10.00 | 361 | 178327 | 35998 | 56077381 |
Disturbance in attention | 166.14 | 10.00 | 338 | 178350 | 32202 | 56081177 |
Nightmare | 165.19 | 10.00 | 234 | 178454 | 16592 | 56096787 |
Infection | 161.27 | 10.00 | 241 | 178447 | 199965 | 55913414 |
Anger | 161.00 | 10.00 | 192 | 178496 | 11480 | 56101899 |
Therapeutic product effect decreased | 157.94 | 10.00 | 183 | 178505 | 169269 | 55944110 |
Hypotonia neonatal | 157.00 | 10.00 | 75 | 178613 | 1049 | 56112330 |
Feeling abnormal | 154.58 | 10.00 | 834 | 177854 | 132768 | 55980611 |
Off label use | 148.70 | 10.00 | 1095 | 177593 | 555085 | 55558294 |
Drug intolerance | 147.09 | 10.00 | 396 | 178292 | 264422 | 55848957 |
Pain | 145.57 | 10.00 | 1376 | 177312 | 661808 | 55451571 |
Restlessness | 141.51 | 10.00 | 281 | 178407 | 26305 | 56087074 |
Muscle injury | 137.53 | 10.00 | 7 | 178681 | 52493 | 56060886 |
Aggression | 136.17 | 10.00 | 248 | 178440 | 21758 | 56091621 |
Hepatic enzyme increased | 134.44 | 10.00 | 210 | 178478 | 171174 | 55942205 |
Generalised tonic-clonic seizure | 129.80 | 10.00 | 277 | 178411 | 27289 | 56086090 |
Foetal exposure during pregnancy | 129.39 | 10.00 | 313 | 178375 | 33510 | 56079869 |
Arthralgia | 127.23 | 10.00 | 1002 | 177686 | 500667 | 55612712 |
Cardiac arrest | 126.97 | 10.00 | 577 | 178111 | 85737 | 56027642 |
Drug dependence | 125.80 | 10.00 | 243 | 178445 | 22290 | 56091089 |
Product substitution issue | 124.49 | 10.00 | 190 | 178498 | 14409 | 56098970 |
Product use issue | 124.26 | 10.00 | 252 | 178436 | 185789 | 55927590 |
Blister | 121.79 | 10.00 | 100 | 178588 | 108787 | 56004592 |
Major depression | 120.15 | 10.00 | 134 | 178554 | 7450 | 56105929 |
Febrile neutropenia | 119.20 | 10.00 | 96 | 178592 | 105449 | 56007930 |
Tachycardia | 119.11 | 10.00 | 656 | 178032 | 105220 | 56008159 |
Peripheral swelling | 118.60 | 10.00 | 367 | 178321 | 234359 | 55879020 |
Folliculitis | 118.00 | 10.00 | 17 | 178671 | 54962 | 56058417 |
Sleep disorder due to general medical condition, insomnia type | 112.82 | 10.00 | 6 | 178682 | 43332 | 56070047 |
Pneumonia | 112.72 | 10.00 | 793 | 177895 | 406305 | 55707074 |
Disorientation | 112.43 | 10.00 | 312 | 178376 | 36301 | 56077078 |
Cardio-respiratory arrest | 111.71 | 10.00 | 408 | 178280 | 54913 | 56058466 |
Respiratory arrest | 109.31 | 10.00 | 276 | 178412 | 30349 | 56083030 |
Pyrexia | 108.62 | 10.00 | 831 | 177857 | 417942 | 55695437 |
Impaired healing | 105.78 | 10.00 | 73 | 178615 | 86768 | 56026611 |
Gestational diabetes | 103.65 | 10.00 | 128 | 178560 | 7936 | 56105443 |
Stomatitis | 103.59 | 10.00 | 139 | 178549 | 120671 | 55992708 |
Poisoning | 99.85 | 10.00 | 160 | 178528 | 12653 | 56100726 |
Muscle rigidity | 98.30 | 10.00 | 144 | 178544 | 10527 | 56102852 |
Psychomotor hyperactivity | 97.03 | 10.00 | 137 | 178551 | 9683 | 56103696 |
Nasopharyngitis | 97.00 | 10.00 | 367 | 178321 | 220592 | 55892787 |
Drug withdrawal syndrome neonatal | 96.76 | 10.00 | 67 | 178621 | 1949 | 56111430 |
Small for dates baby | 96.43 | 10.00 | 84 | 178604 | 3446 | 56109933 |
Extrapyramidal disorder | 95.89 | 10.00 | 154 | 178534 | 12202 | 56101177 |
Insomnia | 95.12 | 10.00 | 979 | 177709 | 190881 | 55922498 |
Mania | 94.12 | 10.00 | 147 | 178541 | 11373 | 56102006 |
Mood swings | 93.97 | 10.00 | 181 | 178507 | 16566 | 56096813 |
Tearfulness | 91.71 | 10.00 | 84 | 178604 | 3684 | 56109695 |
Abnormal dreams | 91.49 | 10.00 | 132 | 178556 | 9517 | 56103862 |
Hyperreflexia | 90.54 | 10.00 | 97 | 178591 | 5153 | 56108226 |
Atrial septal defect | 89.69 | 10.00 | 107 | 178581 | 6399 | 56106980 |
Maternal exposure during pregnancy | 89.04 | 10.00 | 306 | 178382 | 189247 | 55924132 |
Sleep-related eating disorder | 86.70 | 10.00 | 45 | 178643 | 759 | 56112620 |
Mental disorder | 86.62 | 10.00 | 215 | 178473 | 23389 | 56089990 |
Paraesthesia | 85.93 | 10.00 | 708 | 177980 | 129806 | 55983573 |
Mobility decreased | 84.75 | 10.00 | 114 | 178574 | 98877 | 56014502 |
Amnesia | 83.09 | 10.00 | 329 | 178359 | 45993 | 56067386 |
Sepsis | 83.02 | 10.00 | 202 | 178486 | 139638 | 55973741 |
Irritable bowel syndrome | 82.77 | 10.00 | 58 | 178630 | 68400 | 56044979 |
Foetal death | 82.19 | 10.00 | 118 | 178570 | 8469 | 56104910 |
C-reactive protein abnormal | 79.88 | 10.00 | 11 | 178677 | 36798 | 56076581 |
Hallucination | 79.42 | 10.00 | 338 | 178350 | 48811 | 56064568 |
Newborn persistent pulmonary hypertension | 78.38 | 10.00 | 29 | 178659 | 202 | 56113177 |
Altered state of consciousness | 77.53 | 10.00 | 203 | 178485 | 22818 | 56090561 |
Antidepressant drug level increased | 77.20 | 10.00 | 30 | 178658 | 243 | 56113136 |
Platelet count decreased | 76.31 | 10.00 | 138 | 178550 | 106245 | 56007134 |
Anaemia | 75.93 | 10.00 | 517 | 178171 | 266994 | 55846385 |
Musculoskeletal stiffness | 74.50 | 10.00 | 250 | 178438 | 155757 | 55957622 |
Camptocormia | 74.36 | 10.00 | 30 | 178658 | 271 | 56113108 |
Decorticate posture | 74.17 | 10.00 | 30 | 178658 | 273 | 56113106 |
Ill-defined disorder | 74.11 | 10.00 | 65 | 178623 | 68478 | 56044901 |
Intentional product misuse | 74.00 | 10.00 | 342 | 178346 | 51162 | 56062217 |
Homicide | 73.79 | 10.00 | 32 | 178656 | 352 | 56113027 |
Psoriatic arthropathy | 73.23 | 10.00 | 76 | 178612 | 73932 | 56039447 |
Stress cardiomyopathy | 73.21 | 10.00 | 110 | 178578 | 8226 | 56105153 |
Migraine | 73.04 | 10.00 | 499 | 178189 | 86298 | 56027081 |
Myocardial depression | 72.50 | 10.00 | 34 | 178654 | 455 | 56112924 |
Sinusitis | 72.08 | 10.00 | 352 | 178336 | 197229 | 55916150 |
Dizziness | 70.98 | 10.00 | 1627 | 177061 | 374513 | 55738866 |
Nervousness | 70.82 | 10.00 | 228 | 178460 | 28787 | 56084592 |
Mental impairment | 69.55 | 10.00 | 136 | 178552 | 12586 | 56100793 |
Galactorrhoea | 69.00 | 10.00 | 73 | 178615 | 3822 | 56109557 |
Lower respiratory tract infection | 68.78 | 10.00 | 165 | 178523 | 114629 | 55998750 |
Antidepressant drug level above therapeutic | 68.37 | 10.00 | 31 | 178657 | 382 | 56112997 |
Hip arthroplasty | 68.21 | 10.00 | 19 | 178669 | 38604 | 56074775 |
Vertigo | 68.08 | 10.00 | 348 | 178340 | 54224 | 56059155 |
Thinking abnormal | 67.90 | 10.00 | 117 | 178571 | 9824 | 56103555 |
Tardive dyskinesia | 67.73 | 10.00 | 104 | 178584 | 7927 | 56105452 |
Confusional state | 67.73 | 10.00 | 981 | 177707 | 207174 | 55906205 |
Lung diffusion test abnormal | 66.82 | 10.00 | 27 | 178661 | 245 | 56113134 |
Abnormal behaviour | 66.48 | 10.00 | 177 | 178511 | 20095 | 56093284 |
Self-injurious ideation | 66.38 | 10.00 | 57 | 178631 | 2293 | 56111086 |
Electrocardiogram QRS complex prolonged | 65.83 | 10.00 | 84 | 178604 | 5383 | 56107996 |
Neutropenia | 64.74 | 10.00 | 270 | 178418 | 157897 | 55955482 |
Thrombocytopenia | 64.55 | 10.00 | 219 | 178469 | 136005 | 55977374 |
Psychomotor retardation | 63.64 | 10.00 | 68 | 178620 | 3601 | 56109778 |
Cataplexy | 63.33 | 10.00 | 44 | 178644 | 1287 | 56112092 |
Neonatal seizure | 62.83 | 10.00 | 30 | 178658 | 419 | 56112960 |
Disease progression | 61.56 | 10.00 | 153 | 178535 | 105020 | 56008359 |
Loss of consciousness | 61.47 | 10.00 | 573 | 178115 | 108776 | 56004603 |
Cardiogenic shock | 60.22 | 10.00 | 149 | 178539 | 16176 | 56097203 |
Physical assault | 60.02 | 10.00 | 37 | 178651 | 879 | 56112500 |
Muscle twitching | 59.65 | 10.00 | 148 | 178540 | 16094 | 56097285 |
Bipolar disorder | 59.54 | 10.00 | 95 | 178593 | 7485 | 56105894 |
Myoclonus | 58.46 | 10.00 | 141 | 178547 | 15062 | 56098317 |
Large for dates baby | 58.02 | 10.00 | 29 | 178659 | 450 | 56112929 |
Inappropriate affect | 57.44 | 10.00 | 35 | 178653 | 814 | 56112565 |
Respiratory depression | 57.43 | 10.00 | 124 | 178564 | 12311 | 56101068 |
Pleurothotonus | 56.68 | 10.00 | 41 | 178647 | 1280 | 56112099 |
Impulsive behaviour | 56.22 | 10.00 | 43 | 178645 | 1464 | 56111915 |
Drug screen false positive | 55.98 | 10.00 | 34 | 178654 | 786 | 56112593 |
Sedation | 54.99 | 10.00 | 238 | 178450 | 34616 | 56078763 |
Hot flush | 54.85 | 10.00 | 293 | 178395 | 46433 | 56066946 |
Apathy | 54.83 | 10.00 | 94 | 178594 | 7860 | 56105519 |
Congenital tricuspid valve incompetence | 54.65 | 10.00 | 18 | 178670 | 84 | 56113295 |
Sinus tachycardia | 54.44 | 10.00 | 176 | 178512 | 22268 | 56091111 |
Bruxism | 53.72 | 10.00 | 58 | 178630 | 3108 | 56110271 |
Homicidal ideation | 53.55 | 10.00 | 44 | 178644 | 1664 | 56111715 |
Renal impairment | 53.26 | 10.00 | 110 | 178578 | 80603 | 56032776 |
Malignant neoplasm progression | 53.17 | 10.00 | 95 | 178593 | 73492 | 56039887 |
Neonatal hypoxia | 53.13 | 10.00 | 28 | 178660 | 488 | 56112891 |
Lymphocytic oesophagitis | 52.86 | 10.00 | 13 | 178675 | 13 | 56113366 |
Self esteem decreased | 52.79 | 10.00 | 29 | 178659 | 551 | 56112828 |
Hallucination, visual | 52.77 | 10.00 | 148 | 178540 | 17320 | 56096059 |
Mood altered | 52.58 | 10.00 | 125 | 178563 | 13230 | 56100149 |
Drug ineffective | 51.99 | 10.00 | 2388 | 176300 | 916601 | 55196778 |
Meconium in amniotic fluid | 51.88 | 10.00 | 22 | 178666 | 228 | 56113151 |
Depressive symptom | 51.74 | 10.00 | 60 | 178628 | 3481 | 56109898 |
Nystagmus | 51.35 | 10.00 | 77 | 178611 | 5748 | 56107631 |
Tinnitus | 51.18 | 10.00 | 210 | 178478 | 29832 | 56083547 |
Parkinsonism | 50.91 | 10.00 | 101 | 178587 | 9445 | 56103934 |
Benzodiazepine drug level increased | 50.84 | 10.00 | 20 | 178668 | 168 | 56113211 |
Plasma cell myeloma | 50.71 | 10.00 | 44 | 178644 | 46602 | 56066777 |
Psychotic disorder | 50.31 | 10.00 | 177 | 178511 | 23381 | 56089998 |
Gastrointestinal disorder | 50.17 | 10.00 | 186 | 178502 | 112516 | 56000863 |
Product residue present | 50.00 | 10.00 | 61 | 178627 | 3734 | 56109645 |
Libido decreased | 49.69 | 10.00 | 49 | 178639 | 2359 | 56111020 |
Patent ductus arteriosus | 49.63 | 10.00 | 62 | 178626 | 3889 | 56109490 |
General physical health deterioration | 49.47 | 10.00 | 326 | 178362 | 169684 | 55943695 |
Haemoglobin decreased | 49.45 | 10.00 | 238 | 178450 | 133899 | 55979480 |
Urinary incontinence | 48.98 | 10.00 | 205 | 178483 | 29380 | 56083999 |
Hostility | 48.87 | 10.00 | 43 | 178645 | 1788 | 56111591 |
Memory impairment | 48.85 | 10.00 | 454 | 178234 | 86103 | 56027276 |
Neonatal asphyxia | 48.39 | 10.00 | 22 | 178666 | 273 | 56113106 |
Neuroleptic malignant syndrome | 48.00 | 10.00 | 110 | 178578 | 11368 | 56102011 |
Suicidal behaviour | 47.42 | 10.00 | 48 | 178640 | 2385 | 56110994 |
Somnambulism | 47.31 | 10.00 | 69 | 178619 | 5023 | 56108356 |
Emotional disorder | 47.24 | 10.00 | 114 | 178574 | 12181 | 56101198 |
Neonatal respiratory failure | 47.18 | 10.00 | 21 | 178667 | 247 | 56113132 |
Red blood cell sedimentation rate increased | 47.01 | 10.00 | 29 | 178659 | 36594 | 56076785 |
Coma scale abnormal | 46.80 | 10.00 | 67 | 178621 | 4796 | 56108583 |
Dissociation | 46.77 | 10.00 | 49 | 178639 | 2536 | 56110843 |
Feeling of despair | 46.65 | 10.00 | 45 | 178643 | 2108 | 56111271 |
Bezoar | 46.62 | 10.00 | 37 | 178651 | 1331 | 56112048 |
Hallucination, auditory | 46.61 | 10.00 | 109 | 178579 | 11415 | 56101964 |
Weight increased | 46.51 | 10.00 | 1004 | 177684 | 228699 | 55884680 |
Accommodation disorder | 46.48 | 10.00 | 23 | 178665 | 349 | 56113030 |
Dyspnoea | 46.37 | 10.00 | 1481 | 177207 | 591096 | 55522283 |
Paranoia | 46.07 | 10.00 | 104 | 178584 | 10640 | 56102739 |
Neovascularisation | 46.02 | 10.00 | 33 | 178655 | 1016 | 56112363 |
Knee arthroplasty | 45.44 | 10.00 | 44 | 178644 | 44215 | 56069164 |
Diarrhoea | 45.02 | 10.00 | 1617 | 177071 | 636890 | 55476489 |
Euphoric mood | 44.84 | 10.00 | 62 | 178626 | 4296 | 56109083 |
Delusion | 44.18 | 10.00 | 105 | 178583 | 11110 | 56102269 |
C-reactive protein increased | 44.09 | 10.00 | 117 | 178571 | 78567 | 56034812 |
Anticholinergic syndrome | 43.00 | 10.00 | 41 | 178647 | 1893 | 56111486 |
Opsoclonus myoclonus | 42.99 | 10.00 | 17 | 178671 | 145 | 56113234 |
Anorgasmia | 42.66 | 10.00 | 25 | 178663 | 540 | 56112839 |
Hypersomnia | 42.25 | 10.00 | 131 | 178557 | 16210 | 56097169 |
Hypomania | 42.07 | 10.00 | 64 | 178624 | 4838 | 56108541 |
Hypothermia | 42.03 | 10.00 | 110 | 178578 | 12360 | 56101019 |
Pancytopenia | 41.76 | 10.00 | 143 | 178545 | 88572 | 56024807 |
Panic reaction | 41.70 | 10.00 | 56 | 178632 | 3774 | 56109605 |
Drug hypersensitivity | 41.62 | 10.00 | 1156 | 177532 | 274049 | 55839330 |
Single umbilical artery | 41.56 | 10.00 | 19 | 178669 | 239 | 56113140 |
Restless legs syndrome | 41.20 | 10.00 | 133 | 178555 | 16814 | 56096565 |
Personality disorder | 40.86 | 10.00 | 65 | 178623 | 5108 | 56108271 |
Dyskinesia | 40.85 | 10.00 | 192 | 178496 | 28916 | 56084463 |
Lung disorder | 40.67 | 10.00 | 65 | 178623 | 52532 | 56060847 |
Death | 40.52 | 10.00 | 802 | 177886 | 340624 | 55772755 |
Alcohol interaction | 40.04 | 10.00 | 43 | 178645 | 2290 | 56111089 |
Transient tachypnoea of the newborn | 39.20 | 10.00 | 15 | 178673 | 116 | 56113263 |
Intentional product use issue | 39.10 | 10.00 | 173 | 178515 | 99560 | 56013819 |
Malignant mediastinal neoplasm | 38.63 | 10.00 | 28 | 178660 | 877 | 56112502 |
Pneumocystis jirovecii pneumonia | 38.42 | 10.00 | 3 | 178685 | 15698 | 56097681 |
Myelosuppression | 38.39 | 10.00 | 5 | 178683 | 17450 | 56095929 |
Bipolar II disorder | 37.78 | 10.00 | 19 | 178669 | 299 | 56113080 |
Anaphylactic reaction | 37.58 | 10.00 | 82 | 178606 | 58913 | 56054466 |
Atrial fibrillation | 37.40 | 10.00 | 198 | 178490 | 108699 | 56004680 |
Persistent genital arousal disorder | 37.33 | 10.00 | 19 | 178669 | 307 | 56113072 |
Oedema | 37.24 | 10.00 | 134 | 178554 | 81786 | 56031593 |
Congenital vesicoureteric reflux | 36.64 | 10.00 | 10 | 178678 | 20 | 56113359 |
Rapid eye movement sleep behaviour disorder | 36.11 | 10.00 | 16 | 178672 | 186 | 56113193 |
VACTERL syndrome | 36.11 | 10.00 | 9 | 178679 | 10 | 56113369 |
Full blood count abnormal | 36.01 | 10.00 | 173 | 178515 | 26289 | 56087090 |
Pain in extremity | 35.78 | 10.00 | 697 | 177991 | 296734 | 55816645 |
Skin candida | 35.70 | 10.00 | 32 | 178656 | 1364 | 56112015 |
Ventricular septal defect | 35.48 | 10.00 | 54 | 178634 | 4084 | 56109295 |
Hyponatraemia | 35.43 | 10.00 | 487 | 178201 | 101652 | 56011727 |
Fluid retention | 35.42 | 10.00 | 74 | 178614 | 54004 | 56059375 |
Bradycardia neonatal | 35.41 | 10.00 | 26 | 178662 | 831 | 56112548 |
Libido increased | 35.39 | 10.00 | 31 | 178657 | 1281 | 56112098 |
Drug screen positive | 35.22 | 10.00 | 49 | 178639 | 3415 | 56109964 |
Congenital hearing disorder | 35.22 | 10.00 | 9 | 178679 | 12 | 56113367 |
Adverse drug reaction | 34.88 | 10.00 | 99 | 178589 | 65033 | 56048346 |
Pulmonary haemorrhage neonatal | 34.83 | 10.00 | 10 | 178678 | 26 | 56113353 |
Amniorrhexis | 34.83 | 10.00 | 10 | 178678 | 26 | 56113353 |
Negative thoughts | 34.64 | 10.00 | 26 | 178662 | 860 | 56112519 |
Psychotic symptom | 34.26 | 10.00 | 31 | 178657 | 1338 | 56112041 |
Neonatal respiratory distress syndrome | 34.25 | 10.00 | 43 | 178645 | 2711 | 56110668 |
Speech disorder | 34.21 | 10.00 | 220 | 178468 | 37273 | 56076106 |
Pruritus | 33.95 | 10.00 | 756 | 177932 | 315867 | 55797512 |
Adjustment disorder with mixed anxiety and depressed mood | 33.67 | 10.00 | 12 | 178676 | 74 | 56113305 |
Renal papillary necrosis | 33.67 | 10.00 | 16 | 178672 | 221 | 56113158 |
Bone erosion | 33.64 | 10.00 | 4 | 178684 | 14970 | 56098409 |
Gastrointestinal haemorrhage | 33.37 | 10.00 | 126 | 178562 | 75825 | 56037554 |
Tonic convulsion | 33.37 | 10.00 | 29 | 178659 | 1186 | 56112193 |
Rheumatoid nodule | 33.30 | 10.00 | 4 | 178684 | 14853 | 56098526 |
Asphyxia | 33.00 | 10.00 | 63 | 178625 | 5726 | 56107653 |
Endometriosis | 32.98 | 10.00 | 56 | 178632 | 4646 | 56108733 |
Logorrhoea | 32.94 | 10.00 | 39 | 178649 | 2313 | 56111066 |
Postmortem blood drug level abnormal | 32.82 | 10.00 | 18 | 178670 | 341 | 56113038 |
Panic disorder | 32.75 | 10.00 | 40 | 178648 | 2451 | 56110928 |
Yawning | 32.75 | 10.00 | 27 | 178661 | 1026 | 56112353 |
Burnout syndrome | 32.58 | 10.00 | 15 | 178673 | 192 | 56113187 |
Agitation neonatal | 32.15 | 10.00 | 20 | 178668 | 483 | 56112896 |
Blood creatinine increased | 32.10 | 10.00 | 138 | 178550 | 80053 | 56033326 |
Vitamin K decreased | 32.05 | 10.00 | 8 | 178680 | 9 | 56113370 |
Pleural effusion | 31.88 | 10.00 | 151 | 178537 | 85329 | 56028050 |
Hypoventilation neonatal | 31.74 | 10.00 | 9 | 178679 | 22 | 56113357 |
Parkinsonism hyperpyrexia syndrome | 31.61 | 10.00 | 13 | 178675 | 124 | 56113255 |
Brain death | 31.54 | 10.00 | 43 | 178645 | 2940 | 56110439 |
Somatic symptom disorder | 31.45 | 10.00 | 36 | 178652 | 2059 | 56111320 |
Nervous system disorder | 31.12 | 10.00 | 121 | 178567 | 16768 | 56096611 |
Reversible cerebral vasoconstriction syndrome | 30.98 | 10.00 | 38 | 178650 | 2339 | 56111040 |
Leukopenia | 30.96 | 10.00 | 118 | 178570 | 70822 | 56042557 |
Loss of libido | 30.95 | 10.00 | 28 | 178660 | 1208 | 56112171 |
Herpes zoster | 30.74 | 10.00 | 130 | 178558 | 75759 | 56037620 |
Total lung capacity increased | 30.69 | 10.00 | 25 | 178663 | 934 | 56112445 |
White blood cell count decreased | 30.69 | 10.00 | 254 | 178434 | 125736 | 55987643 |
Injection site pain | 30.43 | 10.00 | 232 | 178456 | 116886 | 55996493 |
Tic | 30.28 | 10.00 | 28 | 178660 | 1243 | 56112136 |
False positive investigation result | 30.12 | 10.00 | 20 | 178668 | 542 | 56112837 |
Tachyphrenia | 30.04 | 10.00 | 28 | 178660 | 1256 | 56112123 |
Joint range of motion decreased | 29.98 | 10.00 | 22 | 178666 | 25343 | 56088036 |
Neonatal behavioural syndrome | 29.80 | 10.00 | 10 | 178678 | 50 | 56113329 |
Hypotonia | 29.71 | 10.00 | 77 | 178611 | 8600 | 56104779 |
Respiratory tract inflammation | 29.52 | 10.00 | 20 | 178668 | 561 | 56112818 |
Electrocardiogram QRS complex shortened | 29.49 | 10.00 | 18 | 178670 | 420 | 56112959 |
Cold sweat | 29.48 | 10.00 | 89 | 178599 | 10854 | 56102525 |
Hospitalisation | 29.45 | 10.00 | 130 | 178558 | 74870 | 56038509 |
Erythema | 29.28 | 10.00 | 335 | 178353 | 155604 | 55957775 |
Substance abuse | 29.27 | 10.00 | 52 | 178636 | 4473 | 56108906 |
Haemangioma congenital | 29.19 | 10.00 | 18 | 178670 | 428 | 56112951 |
Bone marrow failure | 29.17 | 10.00 | 28 | 178660 | 28258 | 56085121 |
Drug tolerance decreased | 29.12 | 10.00 | 4 | 178684 | 13407 | 56099972 |
Impaired driving ability | 29.02 | 10.00 | 49 | 178639 | 4047 | 56109332 |
Clonus | 29.00 | 10.00 | 50 | 178638 | 4199 | 56109180 |
Palpitations | 28.98 | 10.00 | 461 | 178227 | 99211 | 56014168 |
Exposure via breast milk | 28.67 | 10.00 | 32 | 178656 | 1780 | 56111599 |
Delirium | 28.67 | 10.00 | 232 | 178456 | 42285 | 56071094 |
Feelings of worthlessness | 28.67 | 10.00 | 16 | 178672 | 314 | 56113065 |
Endolymphatic hydrops | 28.54 | 10.00 | 6 | 178682 | 0 | 56113379 |
Social avoidant behaviour | 28.49 | 10.00 | 40 | 178648 | 2812 | 56110567 |
Psychiatric symptom | 27.97 | 10.00 | 53 | 178635 | 4791 | 56108588 |
Dysarthria | 27.87 | 10.00 | 218 | 178470 | 39332 | 56074047 |
Emotional poverty | 27.79 | 10.00 | 16 | 178672 | 334 | 56113045 |
Middle insomnia | 27.59 | 10.00 | 87 | 178601 | 10863 | 56102516 |
Toxic epidermal necrolysis | 27.54 | 10.00 | 18 | 178670 | 22024 | 56091355 |
Cardiotoxicity | 27.35 | 10.00 | 69 | 178619 | 7581 | 56105798 |
Congenital absence of bile ducts | 27.28 | 10.00 | 8 | 178680 | 23 | 56113356 |
Drug eruption | 27.16 | 10.00 | 25 | 178663 | 25738 | 56087641 |
Neuropathy peripheral | 27.12 | 10.00 | 203 | 178485 | 102690 | 56010689 |
Injection site erythema | 27.05 | 10.00 | 140 | 178548 | 77308 | 56036071 |
Respiratory disorder neonatal | 26.87 | 10.00 | 23 | 178665 | 921 | 56112458 |
Congestive cardiomyopathy | 26.84 | 10.00 | 58 | 178630 | 5761 | 56107618 |
Epilepsy | 26.79 | 10.00 | 154 | 178534 | 25077 | 56088302 |
Frustration tolerance decreased | 26.69 | 10.00 | 61 | 178627 | 6292 | 56107087 |
Post-traumatic stress disorder | 26.63 | 10.00 | 50 | 178638 | 4488 | 56108891 |
Therapeutic product effect incomplete | 26.63 | 10.00 | 212 | 178476 | 105819 | 56007560 |
Victim of sexual abuse | 26.30 | 10.00 | 19 | 178669 | 592 | 56112787 |
Hyperprolactinaemia | 26.20 | 10.00 | 44 | 178644 | 3617 | 56109762 |
Abnormal weight gain | 26.14 | 10.00 | 28 | 178660 | 1487 | 56111892 |
Skin necrosis | 26.11 | 10.00 | 4 | 178684 | 12357 | 56101022 |
Food craving | 26.08 | 10.00 | 28 | 178660 | 1491 | 56111888 |
Antipsychotic drug level increased | 25.97 | 10.00 | 41 | 178647 | 3201 | 56110178 |
Orthostatic intolerance | 25.96 | 10.00 | 24 | 178664 | 1065 | 56112314 |
Persistent depressive disorder | 25.85 | 10.00 | 22 | 178666 | 874 | 56112505 |
Suspected suicide | 25.81 | 10.00 | 55 | 178633 | 5411 | 56107968 |
Enuresis | 25.34 | 10.00 | 34 | 178654 | 2289 | 56111090 |
Encephalopathy neonatal | 25.32 | 10.00 | 7 | 178681 | 15 | 56113364 |
Feeling jittery | 25.28 | 10.00 | 90 | 178598 | 11956 | 56101423 |
Stiff person syndrome | 25.15 | 10.00 | 15 | 178673 | 335 | 56113044 |
Erythema dyschromicum perstans | 25.05 | 10.00 | 9 | 178679 | 57 | 56113322 |
Encephalopathy | 25.05 | 10.00 | 195 | 178493 | 35130 | 56078249 |
Electric shock sensation | 24.99 | 10.00 | 17 | 178671 | 480 | 56112899 |
Obstructive airways disorder | 24.99 | 10.00 | 115 | 178573 | 17167 | 56096212 |
Pyramidal tract syndrome | 24.96 | 10.00 | 15 | 178673 | 340 | 56113039 |
Impaired work ability | 24.93 | 10.00 | 102 | 178586 | 14470 | 56098909 |
Paradoxical drug reaction | 24.84 | 10.00 | 44 | 178644 | 3776 | 56109603 |
Upper respiratory tract infection | 24.82 | 10.00 | 129 | 178559 | 71159 | 56042220 |
Femur fracture | 24.71 | 10.00 | 55 | 178633 | 39240 | 56074139 |
Slow response to stimuli | 24.46 | 10.00 | 22 | 178666 | 942 | 56112437 |
Obsessive thoughts | 24.30 | 10.00 | 17 | 178671 | 503 | 56112876 |
Tenosynovitis | 24.22 | 10.00 | 5 | 178683 | 12456 | 56100923 |
Derealisation | 24.19 | 10.00 | 23 | 178665 | 1058 | 56112321 |
ECG P wave inverted | 23.78 | 10.00 | 5 | 178683 | 0 | 56113379 |
Incoherent | 23.77 | 10.00 | 46 | 178642 | 4223 | 56109156 |
Affective disorder | 23.76 | 10.00 | 54 | 178634 | 5549 | 56107830 |
Phagophobia | 23.68 | 10.00 | 8 | 178680 | 41 | 56113338 |
Tension | 23.45 | 10.00 | 37 | 178651 | 2887 | 56110492 |
Antisocial behaviour | 23.31 | 10.00 | 14 | 178674 | 317 | 56113062 |
Inappropriate antidiuretic hormone secretion | 23.30 | 10.00 | 96 | 178592 | 13660 | 56099719 |
Attention deficit hyperactivity disorder | 23.27 | 10.00 | 35 | 178653 | 2619 | 56110760 |
Drug use disorder | 23.23 | 10.00 | 48 | 178640 | 4621 | 56108758 |
Schizophreniform disorder | 23.15 | 10.00 | 9 | 178679 | 73 | 56113306 |
Starvation ketoacidosis | 23.15 | 10.00 | 9 | 178679 | 73 | 56113306 |
Colitis microscopic | 23.08 | 10.00 | 66 | 178622 | 7809 | 56105570 |
Consciousness fluctuating | 23.07 | 10.00 | 19 | 178669 | 721 | 56112658 |
Coma acidotic | 23.06 | 10.00 | 10 | 178678 | 110 | 56113269 |
HELLP syndrome | 23.04 | 10.00 | 21 | 178667 | 915 | 56112464 |
Fall | 22.99 | 10.00 | 1370 | 177318 | 356140 | 55757239 |
Social anxiety disorder | 22.97 | 10.00 | 15 | 178673 | 395 | 56112984 |
Torsade de pointes | 22.82 | 10.00 | 89 | 178599 | 12351 | 56101028 |
Pulmonary fibrosis | 22.79 | 10.00 | 37 | 178651 | 29721 | 56083658 |
Metabolic syndrome | 22.73 | 10.00 | 25 | 178663 | 1368 | 56112011 |
Neonatal hypotension | 22.51 | 10.00 | 10 | 178678 | 117 | 56113262 |
Eosinophilic pustular folliculitis | 22.31 | 10.00 | 7 | 178681 | 27 | 56113352 |
Hyperacusis | 22.24 | 10.00 | 29 | 178659 | 1899 | 56111480 |
Forced expiratory volume decreased | 22.13 | 10.00 | 47 | 178641 | 4613 | 56108766 |
Neonatal tachypnoea | 22.09 | 10.00 | 8 | 178680 | 52 | 56113327 |
Helplessness | 21.97 | 10.00 | 13 | 178675 | 286 | 56113093 |
Septic shock | 21.79 | 10.00 | 109 | 178579 | 60726 | 56052653 |
Abulia | 21.76 | 10.00 | 15 | 178673 | 433 | 56112946 |
Acute kidney injury | 21.66 | 10.00 | 590 | 178098 | 240173 | 55873206 |
Cholestatic liver injury | 21.63 | 10.00 | 31 | 178657 | 2221 | 56111158 |
Depressed level of consciousness | 21.61 | 10.00 | 274 | 178414 | 56159 | 56057220 |
Congenital pulmonary hypertension | 21.59 | 10.00 | 8 | 178680 | 56 | 56113323 |
Tongue biting | 21.58 | 10.00 | 24 | 178664 | 1330 | 56112049 |
Affect lability | 21.55 | 10.00 | 76 | 178612 | 10049 | 56103330 |
Dyssomnia | 21.55 | 10.00 | 7 | 178681 | 31 | 56113348 |
Congenital multiplex arthrogryposis | 21.55 | 10.00 | 7 | 178681 | 31 | 56113348 |
Unemployment | 21.44 | 10.00 | 5 | 178683 | 3 | 56113376 |
Dependence | 21.44 | 10.00 | 29 | 178659 | 1968 | 56111411 |
Blood immunoglobulin E increased | 21.32 | 10.00 | 36 | 178652 | 2973 | 56110406 |
Rhabdomyolysis | 21.31 | 10.00 | 210 | 178478 | 40448 | 56072931 |
Eye movement disorder | 21.26 | 10.00 | 47 | 178641 | 4742 | 56108637 |
Cytomegalovirus infection | 21.21 | 10.00 | 18 | 178670 | 19278 | 56094101 |
Osteoporosis | 21.18 | 10.00 | 89 | 178599 | 51963 | 56061416 |
Disturbance in sexual arousal | 21.16 | 10.00 | 9 | 178679 | 94 | 56113285 |
Drug level increased | 21.03 | 10.00 | 125 | 178563 | 20600 | 56092779 |
Bradypnoea | 20.96 | 10.00 | 37 | 178651 | 3166 | 56110213 |
Dysphoria | 20.91 | 10.00 | 47 | 178641 | 4795 | 56108584 |
Neonatal disorder | 20.89 | 10.00 | 16 | 178672 | 546 | 56112833 |
Pneumonia aspiration | 20.86 | 10.00 | 175 | 178513 | 32236 | 56081143 |
Blood catecholamines increased | 20.79 | 10.00 | 6 | 178682 | 16 | 56113363 |
Antidepressant discontinuation syndrome | 20.79 | 10.00 | 6 | 178682 | 16 | 56113363 |
Anhedonia | 20.75 | 10.00 | 74 | 178614 | 9840 | 56103539 |
Cough | 20.64 | 10.00 | 648 | 178040 | 259313 | 55854066 |
Adverse event | 20.54 | 10.00 | 98 | 178590 | 55278 | 56058101 |
Trunk injury | 20.53 | 10.00 | 6 | 178682 | 17 | 56113362 |
Ventricular tachycardia | 20.53 | 10.00 | 107 | 178581 | 16794 | 56096585 |
Narcolepsy | 20.51 | 10.00 | 23 | 178665 | 1286 | 56112093 |
Head discomfort | 20.47 | 10.00 | 84 | 178604 | 11930 | 56101449 |
Concussion | 20.30 | 10.00 | 65 | 178623 | 8181 | 56105198 |
Acquired amegakaryocytic thrombocytopenia | 20.28 | 10.00 | 6 | 178682 | 18 | 56113361 |
Ascites | 20.15 | 10.00 | 57 | 178631 | 37487 | 56075892 |
Creutzfeldt-Jakob disease | 20.08 | 10.00 | 10 | 178678 | 154 | 56113225 |
Stress | 20.06 | 10.00 | 280 | 178408 | 58630 | 56054749 |
Skin maceration | 19.94 | 10.00 | 7 | 178681 | 41 | 56113338 |
Soft tissue injury | 19.94 | 10.00 | 25 | 178663 | 1574 | 56111805 |
Vision blurred | 19.90 | 10.00 | 372 | 178316 | 82571 | 56030808 |
Cytokine release syndrome | 19.86 | 10.00 | 5 | 178683 | 10870 | 56102509 |
Dystonia | 19.73 | 10.00 | 85 | 178603 | 12336 | 56101043 |
Conversion disorder | 19.46 | 10.00 | 25 | 178663 | 1613 | 56111766 |
Creatinine renal clearance decreased | 19.43 | 10.00 | 11 | 178677 | 14548 | 56098831 |
Neurodegenerative disorder | 19.40 | 10.00 | 12 | 178676 | 287 | 56113092 |
Electrocardiogram ST-T segment abnormal | 19.36 | 10.00 | 12 | 178676 | 288 | 56113091 |
Cardiac failure | 19.31 | 10.00 | 167 | 178521 | 81926 | 56031453 |
Bundle branch block right | 19.30 | 10.00 | 45 | 178643 | 4702 | 56108677 |
Transient psychosis | 19.27 | 10.00 | 7 | 178681 | 46 | 56113333 |
Hyperbilirubinaemia neonatal | 19.24 | 10.00 | 13 | 178675 | 363 | 56113016 |
Neutrophil count decreased | 19.17 | 10.00 | 87 | 178601 | 49735 | 56063644 |
CYP3A4 polymorphism | 19.12 | 10.00 | 8 | 178680 | 80 | 56113299 |
Atypical fibroxanthoma | 19.02 | 10.00 | 4 | 178684 | 0 | 56113379 |
Neonatal oversedation | 19.02 | 10.00 | 4 | 178684 | 0 | 56113379 |
Bradyphrenia | 18.94 | 10.00 | 55 | 178633 | 6565 | 56106814 |
Feeling drunk | 18.89 | 10.00 | 39 | 178649 | 3753 | 56109626 |
Mucosal inflammation | 18.81 | 10.00 | 71 | 178617 | 42739 | 56070640 |
Sciatic nerve neuropathy | 18.72 | 10.00 | 12 | 178676 | 306 | 56113073 |
Sluggishness | 18.71 | 10.00 | 44 | 178644 | 4624 | 56108755 |
Liver injury | 18.65 | 10.00 | 69 | 178619 | 41779 | 56071600 |
Blood triglycerides increased | 18.62 | 10.00 | 80 | 178608 | 11597 | 56101782 |
Poor weight gain neonatal | 18.61 | 10.00 | 8 | 178680 | 86 | 56113293 |
Feeling guilty | 18.61 | 10.00 | 15 | 178673 | 552 | 56112827 |
Nodule | 18.55 | 10.00 | 19 | 178669 | 18600 | 56094779 |
Violence-related symptom | 18.51 | 10.00 | 13 | 178675 | 387 | 56112992 |
Respiratory tract infection | 18.46 | 10.00 | 56 | 178632 | 36015 | 56077364 |
Intestinal strangulation | 18.45 | 10.00 | 8 | 178680 | 88 | 56113291 |
Live birth | 18.42 | 10.00 | 21 | 178667 | 19584 | 56093795 |
Floppy infant | 18.37 | 10.00 | 8 | 178680 | 89 | 56113290 |
Iodine allergy | 18.36 | 10.00 | 17 | 178671 | 756 | 56112623 |
Right ventricular failure | 18.35 | 10.00 | 15 | 178673 | 16364 | 56097015 |
Hyperkalaemia | 18.30 | 10.00 | 91 | 178597 | 50774 | 56062605 |
Cholestasis | 18.22 | 10.00 | 147 | 178541 | 26766 | 56086613 |
Cerebral vasoconstriction | 18.22 | 10.00 | 20 | 178668 | 1092 | 56112287 |
Hepatic function abnormal | 18.15 | 10.00 | 53 | 178635 | 34505 | 56078874 |
Deja vu | 18.09 | 10.00 | 7 | 178681 | 56 | 56113323 |
Device expulsion | 18.04 | 10.00 | 44 | 178644 | 30405 | 56082974 |
Acute hepatitis B | 17.98 | 10.00 | 12 | 178676 | 328 | 56113051 |
Fear | 17.84 | 10.00 | 94 | 178594 | 14814 | 56098565 |
Cardiomyopathy | 17.76 | 10.00 | 100 | 178588 | 16158 | 56097221 |
Drug ineffective for unapproved indication | 17.76 | 10.00 | 141 | 178547 | 25552 | 56087827 |
Depression suicidal | 17.68 | 10.00 | 24 | 178664 | 1634 | 56111745 |
Drug specific antibody | 17.63 | 10.00 | 27 | 178661 | 2053 | 56111326 |
Anticonvulsant drug level above therapeutic | 17.49 | 10.00 | 14 | 178674 | 510 | 56112869 |
Dropped head syndrome | 17.47 | 10.00 | 8 | 178680 | 101 | 56113278 |
Oedema peripheral | 17.45 | 10.00 | 412 | 178276 | 170842 | 55942537 |
Upper gastrointestinal haemorrhage | 17.45 | 10.00 | 17 | 178671 | 17037 | 56096342 |
Troponin abnormal | 17.41 | 10.00 | 6 | 178682 | 33 | 56113346 |
Hypercalcaemia | 17.30 | 10.00 | 34 | 178654 | 25377 | 56088002 |
Acute myeloid leukaemia | 17.27 | 10.00 | 17 | 178671 | 16955 | 56096424 |
Cerebral infarction | 17.22 | 10.00 | 28 | 178660 | 22477 | 56090902 |
Trismus | 17.03 | 10.00 | 36 | 178652 | 3522 | 56109857 |
Skin ulcer | 16.99 | 10.00 | 64 | 178624 | 38544 | 56074835 |
Persistent left superior vena cava | 16.97 | 10.00 | 6 | 178682 | 36 | 56113343 |
Fatigue | 16.88 | 10.00 | 2220 | 176468 | 786332 | 55327047 |
Cold agglutinins positive | 16.84 | 10.00 | 6 | 178682 | 37 | 56113342 |
Psychiatric decompensation | 16.81 | 10.00 | 21 | 178667 | 1317 | 56112062 |
Splenic infarction | 16.80 | 10.00 | 23 | 178665 | 1579 | 56111800 |
Platelet aggregation abnormal | 16.79 | 10.00 | 4 | 178684 | 3 | 56113376 |
Facial nerve disorder | 16.78 | 10.00 | 14 | 178674 | 541 | 56112838 |
Alcohol use | 16.76 | 10.00 | 26 | 178662 | 1999 | 56111380 |
Sleep terror | 16.76 | 10.00 | 16 | 178672 | 740 | 56112639 |
Pulmonary arterial hypertension | 16.74 | 10.00 | 37 | 178651 | 26466 | 56086913 |
Diverticulitis | 16.72 | 10.00 | 58 | 178630 | 35794 | 56077585 |
Hypnopompic hallucination | 16.70 | 10.00 | 6 | 178682 | 38 | 56113341 |
Hypocalcaemia | 16.69 | 10.00 | 42 | 178646 | 28718 | 56084661 |
Bacteraemia | 16.68 | 10.00 | 15 | 178673 | 15616 | 56097763 |
Loose tooth | 16.66 | 10.00 | 34 | 178654 | 3244 | 56110135 |
Cystic lymphangioma | 16.66 | 10.00 | 5 | 178683 | 16 | 56113363 |
Movement disorder | 16.51 | 10.00 | 111 | 178577 | 19087 | 56094292 |
Alcoholism | 16.42 | 10.00 | 27 | 178661 | 2182 | 56111197 |
Neurological examination abnormal | 16.39 | 10.00 | 10 | 178678 | 233 | 56113146 |
Congenital uterine anomaly | 16.37 | 10.00 | 8 | 178680 | 118 | 56113261 |
Retinal detachment | 16.34 | 10.00 | 46 | 178642 | 5395 | 56107984 |
Palmar-plantar erythrodysaesthesia syndrome | 16.31 | 10.00 | 26 | 178662 | 21039 | 56092340 |
Emotional distress | 16.22 | 10.00 | 155 | 178533 | 29608 | 56083771 |
Therapy non-responder | 16.18 | 10.00 | 121 | 178567 | 61234 | 56052145 |
Pre-existing condition improved | 16.15 | 10.00 | 56 | 178632 | 7342 | 56106037 |
Oropharyngeal pain | 16.11 | 10.00 | 179 | 178509 | 83609 | 56029770 |
Female sexual dysfunction | 16.07 | 10.00 | 6 | 178682 | 43 | 56113336 |
Poor personal hygiene | 16.04 | 10.00 | 11 | 178677 | 315 | 56113064 |
Akinesia | 16.03 | 10.00 | 22 | 178666 | 1514 | 56111865 |
Incontinence | 15.94 | 10.00 | 72 | 178616 | 10663 | 56102716 |
Bipolar I disorder | 15.85 | 10.00 | 23 | 178665 | 1667 | 56111712 |
Post-traumatic neck syndrome | 15.82 | 10.00 | 25 | 178663 | 1953 | 56111426 |
Tumour lysis syndrome | 15.77 | 10.00 | 3 | 178685 | 7920 | 56105459 |
Transfusion | 15.63 | 10.00 | 12 | 178676 | 13508 | 56099871 |
Central nervous system necrosis | 15.62 | 10.00 | 8 | 178680 | 131 | 56113248 |
Peak expiratory flow rate decreased | 15.55 | 10.00 | 14 | 178674 | 600 | 56112779 |
Tremor neonatal | 15.52 | 10.00 | 8 | 178680 | 133 | 56113246 |
Neoplasm progression | 15.47 | 10.00 | 51 | 178637 | 31965 | 56081414 |
Sleep talking | 15.46 | 10.00 | 17 | 178671 | 930 | 56112449 |
Nephropathy toxic | 15.42 | 10.00 | 4 | 178684 | 8523 | 56104856 |
Pancreatic enlargement | 15.40 | 10.00 | 6 | 178682 | 49 | 56113330 |
Vasoplegia syndrome | 15.39 | 10.00 | 20 | 178668 | 1305 | 56112074 |
Slow speech | 15.37 | 10.00 | 20 | 178668 | 1307 | 56112072 |
Ataxia | 15.35 | 10.00 | 88 | 178600 | 14315 | 56099064 |
Premature delivery | 15.33 | 10.00 | 40 | 178648 | 27020 | 56086359 |
Basal cell carcinoma | 15.29 | 10.00 | 36 | 178652 | 25185 | 56088194 |
Cytopenia | 15.12 | 10.00 | 6 | 178682 | 9749 | 56103630 |
Blood lactic acid increased | 15.11 | 10.00 | 48 | 178640 | 6016 | 56107363 |
Urinary tract infection | 15.11 | 10.00 | 617 | 178071 | 239896 | 55873483 |
Kleptomania | 15.07 | 10.00 | 5 | 178683 | 24 | 56113355 |
Abnormal sleep-related event | 15.06 | 10.00 | 15 | 178673 | 731 | 56112648 |
Labour complication | 14.97 | 10.00 | 7 | 178681 | 93 | 56113286 |
Apallic syndrome | 14.91 | 10.00 | 14 | 178674 | 634 | 56112745 |
Foetal alcohol syndrome | 14.90 | 10.00 | 5 | 178683 | 25 | 56113354 |
Right ventricular systolic pressure decreased | 14.90 | 10.00 | 5 | 178683 | 25 | 56113354 |
Purging | 14.89 | 10.00 | 6 | 178682 | 54 | 56113325 |
Bladder trabeculation | 14.89 | 10.00 | 6 | 178682 | 54 | 56113325 |
Merycism | 14.86 | 10.00 | 9 | 178679 | 207 | 56113172 |
Activation syndrome | 14.86 | 10.00 | 9 | 178679 | 207 | 56113172 |
Hypokinesia | 14.83 | 10.00 | 80 | 178608 | 12723 | 56100656 |
Increased appetite | 14.83 | 10.00 | 61 | 178627 | 8674 | 56104705 |
Sternal fracture | 14.80 | 10.00 | 25 | 178663 | 2065 | 56111314 |
Language disorder | 14.80 | 10.00 | 24 | 178664 | 1917 | 56111462 |
Unresponsive to stimuli | 14.79 | 10.00 | 160 | 178528 | 31565 | 56081814 |
Neurotoxicity | 14.76 | 10.00 | 17 | 178671 | 15778 | 56097601 |
Ligament pain | 14.74 | 10.00 | 9 | 178679 | 210 | 56113169 |
Persecutory delusion | 14.69 | 10.00 | 28 | 178660 | 2542 | 56110837 |
Lung diffusion test decreased | 14.60 | 10.00 | 14 | 178674 | 651 | 56112728 |
Musculoskeletal pain | 14.58 | 10.00 | 176 | 178512 | 80976 | 56032403 |
Infantile apnoea | 14.56 | 10.00 | 16 | 178672 | 875 | 56112504 |
Epstein-Barr virus infection | 14.49 | 10.00 | 3 | 178685 | 7460 | 56105919 |
Osteoarthritis | 14.48 | 10.00 | 174 | 178514 | 80122 | 56033257 |
Urticaria | 14.47 | 10.00 | 349 | 178339 | 144327 | 55969052 |
Brief psychotic disorder with marked stressors | 14.43 | 10.00 | 6 | 178682 | 59 | 56113320 |
Foetal arrhythmia | 14.42 | 10.00 | 8 | 178680 | 155 | 56113224 |
Ideas of reference | 14.34 | 10.00 | 7 | 178681 | 103 | 56113276 |
Anal atresia | 14.24 | 10.00 | 11 | 178677 | 380 | 56112999 |
Marital problem | 14.20 | 10.00 | 8 | 178680 | 160 | 56113219 |
Liver function test increased | 14.16 | 10.00 | 44 | 178644 | 28089 | 56085290 |
Flight of ideas | 14.14 | 10.00 | 11 | 178677 | 384 | 56112995 |
Exposure via ingestion | 14.13 | 10.00 | 29 | 178659 | 2779 | 56110600 |
Accidental exposure to product by child | 14.09 | 10.00 | 18 | 178670 | 1155 | 56112224 |
Cerebral haematoma | 14.06 | 10.00 | 32 | 178656 | 3291 | 56110088 |
Cogwheel rigidity | 14.03 | 10.00 | 23 | 178665 | 1854 | 56111525 |
Postmortem blood drug level increased | 14.02 | 10.00 | 13 | 178675 | 579 | 56112800 |
Nonspecific reaction | 13.99 | 10.00 | 23 | 178665 | 1858 | 56111521 |
Anuria | 13.97 | 10.00 | 74 | 178614 | 11686 | 56101693 |
Perinatal depression | 13.89 | 10.00 | 13 | 178675 | 586 | 56112793 |
Arthritis | 13.87 | 10.00 | 228 | 178460 | 99624 | 56013755 |
Pulmonary artery stenosis congenital | 13.78 | 10.00 | 9 | 178679 | 237 | 56113142 |
Haemangioma | 13.77 | 10.00 | 27 | 178661 | 2503 | 56110876 |
Drug abuser | 13.77 | 10.00 | 29 | 178659 | 2830 | 56110549 |
Somnolence neonatal | 13.76 | 10.00 | 7 | 178681 | 113 | 56113266 |
Foot deformity | 13.67 | 10.00 | 35 | 178653 | 23790 | 56089589 |
Pneumonitis | 13.45 | 10.00 | 53 | 178635 | 31511 | 56081868 |
Cognitive disorder | 13.44 | 10.00 | 225 | 178463 | 48908 | 56064471 |
Immunodeficiency | 13.42 | 10.00 | 19 | 178669 | 16138 | 56097241 |
Rhinorrhoea | 13.42 | 10.00 | 116 | 178572 | 56921 | 56056458 |
Barotrauma | 13.40 | 10.00 | 8 | 178680 | 179 | 56113200 |
Tympanic membrane disorder | 13.36 | 10.00 | 8 | 178680 | 180 | 56113199 |
Respiratory rate decreased | 13.35 | 10.00 | 31 | 178657 | 3231 | 56110148 |
Proteinuria | 13.31 | 10.00 | 22 | 178666 | 17548 | 56095831 |
Hereditary non-polyposis colorectal cancer syndrome | 13.28 | 10.00 | 7 | 178681 | 122 | 56113257 |
Divorced | 13.28 | 10.00 | 4 | 178684 | 13 | 56113366 |
Radius fracture | 13.27 | 10.00 | 31 | 178657 | 3244 | 56110135 |
Jaundice neonatal | 13.24 | 10.00 | 15 | 178673 | 848 | 56112531 |
Foetal growth restriction | 13.19 | 10.00 | 51 | 178637 | 7048 | 56106331 |
Muscle tone disorder | 13.18 | 10.00 | 7 | 178681 | 124 | 56113255 |
Macular degeneration | 13.13 | 10.00 | 25 | 178663 | 18883 | 56094496 |
Ventricular hypokinesia | 13.09 | 10.00 | 36 | 178652 | 4165 | 56109214 |
Dry mouth | 13.08 | 10.00 | 281 | 178407 | 63924 | 56049455 |
Injection site rash | 13.07 | 10.00 | 21 | 178667 | 16937 | 56096442 |
Thrombosis | 13.05 | 10.00 | 123 | 178565 | 59304 | 56054075 |
Aplastic anaemia | 13.03 | 10.00 | 6 | 178682 | 8922 | 56104457 |
Myelodysplastic syndrome | 12.94 | 10.00 | 20 | 178668 | 16386 | 56096993 |
Respiratory failure | 12.90 | 10.00 | 218 | 178470 | 94844 | 56018535 |
Respiratory acidosis | 12.90 | 10.00 | 46 | 178642 | 6117 | 56107262 |
Sleep apnoea syndrome | 12.88 | 10.00 | 133 | 178555 | 25928 | 56087451 |
Mechanical urticaria | 12.86 | 10.00 | 11 | 178677 | 440 | 56112939 |
Focal dyscognitive seizures | 12.85 | 10.00 | 28 | 178660 | 2797 | 56110582 |
Headache | 12.82 | 10.00 | 1991 | 176697 | 557053 | 55556326 |
Product formulation issue | 12.82 | 10.00 | 12 | 178676 | 541 | 56112838 |
Parkinsonian gait | 12.82 | 10.00 | 11 | 178677 | 442 | 56112937 |
Blood calcium decreased | 12.82 | 10.00 | 36 | 178652 | 23733 | 56089646 |
Neuropsychiatric syndrome | 12.81 | 10.00 | 5 | 178683 | 41 | 56113338 |
Accidental exposure to product | 12.80 | 10.00 | 38 | 178650 | 24609 | 56088770 |
Arachnoid cyst | 12.80 | 10.00 | 8 | 178680 | 195 | 56113184 |
Sleep disorder | 12.79 | 10.00 | 293 | 178395 | 67370 | 56046009 |
Brain contusion | 12.75 | 10.00 | 12 | 178676 | 545 | 56112834 |
Colitis | 12.74 | 10.00 | 79 | 178609 | 41732 | 56071647 |
Electroencephalogram abnormal | 12.73 | 10.00 | 32 | 178656 | 3507 | 56109872 |
Ocular hypertension | 12.72 | 10.00 | 15 | 178673 | 886 | 56112493 |
Hypertonia | 12.68 | 10.00 | 35 | 178653 | 4057 | 56109322 |
Skin disorder | 12.65 | 10.00 | 42 | 178646 | 26267 | 56087112 |
Grip strength decreased | 12.65 | 10.00 | 20 | 178668 | 16236 | 56097143 |
Wheezing | 12.62 | 10.00 | 165 | 178523 | 74861 | 56038518 |
Blood creatine phosphokinase increased | 12.59 | 10.00 | 140 | 178548 | 27812 | 56085567 |
Respiration abnormal | 12.58 | 10.00 | 43 | 178645 | 5598 | 56107781 |
Balance disorder | 12.55 | 10.00 | 325 | 178363 | 76195 | 56037184 |
Lip and/or oral cavity cancer | 12.55 | 10.00 | 13 | 178675 | 664 | 56112715 |
Cellulitis | 12.54 | 10.00 | 165 | 178523 | 74784 | 56038595 |
Bladder dilatation | 12.54 | 10.00 | 14 | 178674 | 779 | 56112600 |
Multiple allergies | 12.54 | 10.00 | 9 | 178679 | 10487 | 56102892 |
Back pain | 12.53 | 10.00 | 620 | 178068 | 236550 | 55876829 |
Decreased interest | 12.52 | 10.00 | 29 | 178659 | 3017 | 56110362 |
Metastases to bone | 12.52 | 10.00 | 27 | 178661 | 19481 | 56093898 |
Tubulointerstitial nephritis | 12.50 | 10.00 | 21 | 178667 | 16644 | 56096735 |
Hypnagogic hallucination | 12.47 | 10.00 | 7 | 178681 | 139 | 56113240 |
Coarctation of the aorta | 12.46 | 10.00 | 12 | 178676 | 561 | 56112818 |
Arrhythmia | 12.45 | 10.00 | 168 | 178520 | 34915 | 56078464 |
Second primary malignancy | 12.42 | 10.00 | 4 | 178684 | 7398 | 56105981 |
Rash pruritic | 12.36 | 10.00 | 107 | 178581 | 52487 | 56060892 |
Formication | 12.35 | 10.00 | 34 | 178654 | 3936 | 56109443 |
Respiratory tract congestion | 12.30 | 10.00 | 19 | 178669 | 15572 | 56097807 |
Drug level above therapeutic | 12.25 | 10.00 | 36 | 178652 | 4326 | 56109053 |
Anaemia of pregnancy | 12.25 | 10.00 | 6 | 178682 | 89 | 56113290 |
Obsessive rumination | 12.20 | 10.00 | 3 | 178685 | 3 | 56113376 |
Anxiety disorder due to a general medical condition | 12.20 | 10.00 | 3 | 178685 | 3 | 56113376 |
Antidepressant drug level decreased | 12.20 | 10.00 | 3 | 178685 | 3 | 56113376 |
Ulcer | 12.17 | 10.00 | 34 | 178654 | 22451 | 56090928 |
Feeling of body temperature change | 12.06 | 10.00 | 37 | 178651 | 4552 | 56108827 |
Bradycardia | 12.05 | 10.00 | 290 | 178398 | 67214 | 56046165 |
Therapeutic response unexpected | 12.03 | 10.00 | 94 | 178594 | 16950 | 56096429 |
Substance use | 12.02 | 10.00 | 10 | 178678 | 385 | 56112994 |
Dialysis | 12.02 | 10.00 | 8 | 178680 | 9694 | 56103685 |
No adverse event | 12.00 | 10.00 | 67 | 178621 | 36307 | 56077072 |
Drug withdrawal convulsions | 12.00 | 10.00 | 18 | 178670 | 1344 | 56112035 |
Regressive behaviour | 11.95 | 10.00 | 7 | 178681 | 151 | 56113228 |
Multiple sclerosis | 11.95 | 10.00 | 138 | 178550 | 27664 | 56085715 |
Housebound | 11.95 | 10.00 | 8 | 178680 | 220 | 56113159 |
Liver disorder | 11.94 | 10.00 | 87 | 178601 | 44283 | 56069096 |
Exposure via transplant | 11.92 | 10.00 | 4 | 178684 | 20 | 56113359 |
Urinary retention | 11.91 | 10.00 | 139 | 178549 | 27935 | 56085444 |
Device related infection | 11.90 | 10.00 | 33 | 178655 | 21847 | 56091532 |
Exposure during pregnancy | 11.89 | 10.00 | 538 | 178150 | 135804 | 55977575 |
Delusional disorder, unspecified type | 11.89 | 10.00 | 10 | 178678 | 391 | 56112988 |
Polydactyly | 11.88 | 10.00 | 9 | 178679 | 302 | 56113077 |
Personality change | 11.82 | 10.00 | 43 | 178645 | 5774 | 56107605 |
Parachute mitral valve | 11.73 | 10.00 | 6 | 178682 | 98 | 56113281 |
Haemophagocytic lymphohistiocytosis | 11.71 | 10.00 | 8 | 178680 | 9564 | 56103815 |
Amenorrhoea | 11.69 | 10.00 | 58 | 178630 | 8928 | 56104451 |
Feeling hot | 11.66 | 10.00 | 192 | 178496 | 41595 | 56071784 |
Photophobia | 11.60 | 10.00 | 89 | 178599 | 15961 | 56097418 |
COVID-19 | 11.57 | 10.00 | 168 | 178520 | 74890 | 56038489 |
Haematocrit decreased | 11.53 | 10.00 | 69 | 178619 | 36760 | 56076619 |
Xanthopsia | 11.52 | 10.00 | 7 | 178681 | 162 | 56113217 |
Intestinal anastomosis complication | 11.51 | 10.00 | 8 | 178680 | 234 | 56113145 |
Hypertonia neonatal | 11.45 | 10.00 | 8 | 178680 | 236 | 56113143 |
Breech presentation | 11.39 | 10.00 | 16 | 178672 | 1125 | 56112254 |
Pulmonary vein occlusion | 11.36 | 10.00 | 6 | 178682 | 105 | 56113274 |
Thrombotic microangiopathy | 11.33 | 10.00 | 8 | 178680 | 9403 | 56103976 |
Ocular hyperaemia | 11.33 | 10.00 | 34 | 178654 | 21945 | 56091434 |
Morbihan disease | 11.32 | 10.00 | 4 | 178684 | 24 | 56113355 |
Cardiac valve disease | 11.31 | 10.00 | 33 | 178655 | 3948 | 56109431 |
Ultrasound abdomen abnormal | 11.30 | 10.00 | 5 | 178683 | 58 | 56113321 |
Pleural rub | 11.30 | 10.00 | 5 | 178683 | 58 | 56113321 |
Cataract | 11.28 | 10.00 | 106 | 178582 | 51141 | 56062238 |
Osteonecrosis of jaw | 11.25 | 10.00 | 61 | 178627 | 33297 | 56080082 |
Transplant rejection | 11.25 | 10.00 | 9 | 178679 | 9925 | 56103454 |
Pre-eclampsia | 11.20 | 10.00 | 55 | 178633 | 8431 | 56104948 |
Anxiety disorder | 11.18 | 10.00 | 32 | 178656 | 3788 | 56109591 |
Blood urea increased | 11.14 | 10.00 | 40 | 178648 | 24433 | 56088946 |
Hepatocellular injury | 11.13 | 10.00 | 131 | 178557 | 26383 | 56086996 |
Left ventricular hypertrophy | 11.12 | 10.00 | 38 | 178650 | 4946 | 56108433 |
Parasomnia | 11.08 | 10.00 | 10 | 178678 | 430 | 56112949 |
Gun shot wound | 11.07 | 10.00 | 6 | 178682 | 111 | 56113268 |
Head injury | 11.04 | 10.00 | 125 | 178563 | 24941 | 56088438 |
Congenital pharyngeal anomaly | 10.99 | 10.00 | 3 | 178685 | 6 | 56113373 |
Bronchiectasis | 10.99 | 10.00 | 68 | 178620 | 11366 | 56102013 |
Skin texture abnormal | 10.97 | 10.00 | 10 | 178678 | 436 | 56112943 |
Dissociative amnesia | 10.92 | 10.00 | 4 | 178684 | 27 | 56113352 |
Platelet aggregation decreased | 10.92 | 10.00 | 4 | 178684 | 27 | 56113352 |
Congenital naevus | 10.90 | 10.00 | 7 | 178681 | 179 | 56113200 |
Enthesopathy | 10.89 | 10.00 | 6 | 178682 | 8057 | 56105322 |
Urosepsis | 10.84 | 10.00 | 23 | 178665 | 16693 | 56096686 |
Obsessive-compulsive disorder | 10.80 | 10.00 | 31 | 178657 | 3675 | 56109704 |
Pleural disorder | 10.79 | 10.00 | 11 | 178677 | 551 | 56112828 |
Muscle tightness | 10.77 | 10.00 | 65 | 178623 | 10771 | 56102608 |
Rhythm idioventricular | 10.76 | 10.00 | 7 | 178681 | 183 | 56113196 |
Agoraphobia | 10.76 | 10.00 | 9 | 178679 | 349 | 56113030 |
Peritonitis | 10.75 | 10.00 | 22 | 178666 | 16180 | 56097199 |
Hallucination, tactile | 10.73 | 10.00 | 8 | 178680 | 262 | 56113117 |
Staring | 10.72 | 10.00 | 18 | 178670 | 1480 | 56111899 |
Heart rate increased | 10.71 | 10.00 | 343 | 178345 | 82930 | 56030449 |
Blood bilirubin increased | 10.70 | 10.00 | 62 | 178626 | 33292 | 56080087 |
Haemolytic anaemia | 10.69 | 10.00 | 9 | 178679 | 9676 | 56103703 |
Dreamy state | 10.68 | 10.00 | 4 | 178684 | 29 | 56113350 |
Hyperemesis gravidarum | 10.65 | 10.00 | 11 | 178677 | 560 | 56112819 |
Sleep paralysis | 10.65 | 10.00 | 11 | 178677 | 560 | 56112819 |
Hypoglycaemia | 10.64 | 10.00 | 242 | 178446 | 55573 | 56057806 |
Cartilage injury | 10.63 | 10.00 | 20 | 178668 | 1798 | 56111581 |
Injection site bruising | 10.62 | 10.00 | 75 | 178613 | 38446 | 56074933 |
Prescription form tampering | 10.62 | 10.00 | 11 | 178677 | 562 | 56112817 |
Communication disorder | 10.61 | 10.00 | 23 | 178665 | 2290 | 56111089 |
Pathogen resistance | 10.50 | 10.00 | 3 | 178685 | 5997 | 56107382 |
Hepatotoxicity | 10.49 | 10.00 | 57 | 178631 | 31096 | 56082283 |
Hypoglycaemic seizure | 10.46 | 10.00 | 10 | 178678 | 463 | 56112916 |
Impatience | 10.46 | 10.00 | 9 | 178679 | 363 | 56113016 |
Distributive shock | 10.45 | 10.00 | 15 | 178673 | 1076 | 56112303 |
Skin discolouration | 10.43 | 10.00 | 65 | 178623 | 34291 | 56079088 |
Therapeutic response decreased | 10.42 | 10.00 | 112 | 178576 | 52646 | 56060733 |
Toxicologic test abnormal | 10.41 | 10.00 | 12 | 178676 | 692 | 56112687 |
Hypersexuality | 10.39 | 10.00 | 10 | 178678 | 467 | 56112912 |
Foetal heart rate deceleration abnormality | 10.39 | 10.00 | 10 | 178678 | 467 | 56112912 |
Polycythaemia | 10.37 | 10.00 | 13 | 178675 | 818 | 56112561 |
Throat irritation | 10.36 | 10.00 | 61 | 178627 | 32622 | 56080757 |
Tongue discomfort | 10.36 | 10.00 | 21 | 178667 | 1995 | 56111384 |
Hypoalbuminaemia | 10.35 | 10.00 | 11 | 178677 | 10588 | 56102791 |
Pulmonary pain | 10.32 | 10.00 | 26 | 178662 | 2854 | 56110525 |
Hypervolaemia | 10.30 | 10.00 | 46 | 178642 | 26412 | 56086967 |
Coordination abnormal | 10.27 | 10.00 | 72 | 178616 | 12549 | 56100830 |
Long QT syndrome | 10.23 | 10.00 | 27 | 178661 | 3049 | 56110330 |
Glassy eyes | 10.21 | 10.00 | 5 | 178683 | 74 | 56113305 |
Intellectual disability | 10.21 | 10.00 | 13 | 178675 | 831 | 56112548 |
Foaming at mouth | 10.19 | 10.00 | 15 | 178673 | 1101 | 56112278 |
Attention-seeking behaviour | 10.15 | 10.00 | 5 | 178683 | 75 | 56113304 |
Impulse-control disorder | 10.15 | 10.00 | 12 | 178676 | 711 | 56112668 |
Maternal exposure during breast feeding | 10.14 | 10.00 | 30 | 178658 | 3617 | 56109762 |
Subacute kidney injury | 10.14 | 10.00 | 3 | 178685 | 9 | 56113370 |
Crush injury | 10.14 | 10.00 | 3 | 178685 | 9 | 56113370 |
Pain in jaw | 10.07 | 10.00 | 80 | 178608 | 39956 | 56073423 |
Pseudophaeochromocytoma | 10.04 | 10.00 | 5 | 178683 | 77 | 56113302 |
Tanning | 10.04 | 10.00 | 5 | 178683 | 77 | 56113302 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Completed suicide | 780.40 | 11.04 | 1009 | 72523 | 90505 | 31533307 |
Serotonin syndrome | 750.68 | 11.04 | 494 | 73038 | 18279 | 31605533 |
Drug withdrawal syndrome | 453.50 | 11.04 | 364 | 73168 | 18386 | 31605426 |
Suicide attempt | 453.06 | 11.04 | 493 | 73039 | 36755 | 31587057 |
Suicidal ideation | 441.30 | 11.04 | 481 | 73051 | 35925 | 31587887 |
Intentional overdose | 435.49 | 11.04 | 508 | 73024 | 40881 | 31582931 |
Toxicity to various agents | 420.13 | 11.04 | 1140 | 72392 | 180347 | 31443465 |
Depression | 294.32 | 11.04 | 650 | 72882 | 90165 | 31533647 |
Overdose | 286.89 | 11.04 | 617 | 72915 | 84047 | 31539765 |
Withdrawal syndrome | 226.54 | 11.04 | 200 | 73332 | 11517 | 31612295 |
Anxiety | 207.03 | 11.04 | 569 | 72963 | 90464 | 31533348 |
Foetal exposure during pregnancy | 179.24 | 11.04 | 332 | 73200 | 40544 | 31583268 |
Hyperhidrosis | 174.26 | 11.04 | 442 | 73090 | 66951 | 31556861 |
Drug abuse | 171.90 | 11.04 | 520 | 73012 | 87238 | 31536574 |
Coma | 164.09 | 11.04 | 321 | 73211 | 40829 | 31582983 |
Respiratory disorder neonatal | 155.98 | 11.04 | 74 | 73458 | 1421 | 31622391 |
Agitation | 153.47 | 11.04 | 368 | 73164 | 53801 | 31570011 |
Maternal exposure during pregnancy | 151.53 | 11.04 | 108 | 73424 | 4548 | 31619264 |
Mania | 148.85 | 11.04 | 142 | 73390 | 9035 | 31614777 |
Drug withdrawal syndrome neonatal | 147.03 | 11.04 | 95 | 73437 | 3397 | 31620415 |
Febrile neutropenia | 142.99 | 11.04 | 52 | 73480 | 121797 | 31502015 |
Sopor | 142.19 | 11.04 | 154 | 73378 | 11398 | 31612414 |
Disturbance in attention | 137.86 | 11.04 | 212 | 73320 | 22238 | 31601574 |
Pneumonia | 137.09 | 11.04 | 366 | 73166 | 334946 | 31288866 |
Drug interaction | 131.35 | 11.04 | 880 | 72652 | 207663 | 31416149 |
Poisoning deliberate | 129.41 | 11.04 | 119 | 73413 | 7225 | 31616587 |
Mydriasis | 126.95 | 11.04 | 112 | 73420 | 6440 | 31617372 |
Exposure during pregnancy | 122.60 | 11.04 | 124 | 73408 | 8474 | 31615338 |
Pyrexia | 122.35 | 11.04 | 334 | 73198 | 303506 | 31320306 |
Nightmare | 117.63 | 11.04 | 143 | 73389 | 11994 | 31611818 |
Major depression | 116.67 | 11.04 | 89 | 73443 | 4164 | 31619648 |
Intentional self-injury | 113.31 | 11.04 | 147 | 73385 | 13168 | 31610644 |
Anaemia | 111.84 | 11.04 | 203 | 73329 | 213319 | 31410493 |
Tremor | 107.23 | 11.04 | 405 | 73127 | 76015 | 31547797 |
Selective eating disorder | 106.64 | 11.04 | 60 | 73472 | 1660 | 31622152 |
Myoclonus | 104.59 | 11.04 | 145 | 73387 | 13845 | 31609967 |
Cataplexy | 104.22 | 11.04 | 37 | 73495 | 322 | 31623490 |
Restlessness | 103.93 | 11.04 | 191 | 73341 | 23170 | 31600642 |
Sedation | 103.90 | 11.04 | 170 | 73362 | 18795 | 31605017 |
Hypotonia neonatal | 101.61 | 11.04 | 53 | 73479 | 1256 | 31622556 |
Small for dates baby | 101.39 | 11.04 | 77 | 73455 | 3578 | 31620234 |
Depressed mood | 100.99 | 11.04 | 161 | 73371 | 17414 | 31606398 |
Somnolence | 98.43 | 11.04 | 474 | 73058 | 98971 | 31524841 |
Bipolar disorder | 93.60 | 11.04 | 74 | 73458 | 3650 | 31620162 |
Sepsis | 91.14 | 11.04 | 132 | 73400 | 151797 | 31472015 |
Neonatal respiratory distress syndrome | 90.85 | 11.04 | 74 | 73458 | 3811 | 31620001 |
Electrocardiogram QT prolonged | 90.75 | 11.04 | 242 | 73290 | 37745 | 31586067 |
Hyperreflexia | 90.47 | 11.04 | 66 | 73466 | 2883 | 31620929 |
Irritability | 89.31 | 11.04 | 177 | 73355 | 22712 | 31601100 |
Drug dependence | 88.58 | 11.04 | 175 | 73357 | 22404 | 31601408 |
Neutropenia | 84.13 | 11.04 | 122 | 73410 | 140242 | 31483570 |
Seizure | 79.65 | 11.04 | 448 | 73084 | 99320 | 31524492 |
Poisoning | 79.63 | 11.04 | 109 | 73423 | 10282 | 31613530 |
Dyspnoea | 76.28 | 11.04 | 476 | 73056 | 343003 | 31280809 |
Rash | 76.13 | 11.04 | 228 | 73304 | 201258 | 31422554 |
Erectile dysfunction | 75.35 | 11.04 | 149 | 73383 | 19086 | 31604726 |
Psychotic symptom | 74.26 | 11.04 | 46 | 73486 | 1526 | 31622286 |
Diarrhoea | 73.38 | 11.04 | 498 | 73034 | 351911 | 31271901 |
Dyskinesia | 72.49 | 11.04 | 154 | 73378 | 20756 | 31603056 |
Disease progression | 72.41 | 11.04 | 62 | 73470 | 90402 | 31533410 |
Aggression | 71.04 | 11.04 | 219 | 73313 | 37072 | 31586740 |
Acute kidney injury | 69.33 | 11.04 | 374 | 73158 | 279340 | 31344472 |
Off label use | 69.21 | 11.04 | 497 | 73035 | 346777 | 31277035 |
Atrial septal defect | 67.74 | 11.04 | 82 | 73450 | 6845 | 31616967 |
Agitation neonatal | 67.74 | 11.04 | 38 | 73494 | 1045 | 31622767 |
Bradycardia neonatal | 66.77 | 11.04 | 36 | 73496 | 914 | 31622898 |
Talipes | 62.80 | 11.04 | 44 | 73488 | 1802 | 31622010 |
Malignant neoplasm progression | 62.18 | 11.04 | 55 | 73477 | 78943 | 31544869 |
Rheumatoid arthritis | 62.09 | 11.04 | 17 | 73515 | 47792 | 31576020 |
Hypertonia | 59.83 | 11.04 | 59 | 73473 | 3909 | 31619903 |
Anger | 59.76 | 11.04 | 99 | 73433 | 11054 | 31612758 |
Delusion | 59.65 | 11.04 | 103 | 73429 | 11894 | 31611918 |
Antipsychotic drug level above therapeutic | 59.58 | 11.04 | 36 | 73496 | 1141 | 31622671 |
Platelet count decreased | 59.50 | 11.04 | 103 | 73429 | 110332 | 31513480 |
Insomnia | 57.57 | 11.04 | 397 | 73135 | 94439 | 31529373 |
Homicide | 56.40 | 11.04 | 32 | 73500 | 900 | 31622912 |
Infantile apnoea | 56.33 | 11.04 | 32 | 73500 | 902 | 31622910 |
Hypertonia neonatal | 56.04 | 11.04 | 25 | 73507 | 414 | 31623398 |
Somnambulism | 55.74 | 11.04 | 49 | 73483 | 2803 | 31621009 |
Hallucination, auditory | 55.56 | 11.04 | 92 | 73440 | 10268 | 31613544 |
Postmortem blood drug level increased | 55.46 | 11.04 | 21 | 73511 | 223 | 31623589 |
Psychotic disorder | 54.22 | 11.04 | 143 | 73389 | 22150 | 31601662 |
Intentional product misuse | 53.89 | 11.04 | 202 | 73330 | 37749 | 31586063 |
Altered state of consciousness | 53.21 | 11.04 | 137 | 73395 | 20914 | 31602898 |
Interstitial lung disease | 53.00 | 11.04 | 39 | 73493 | 61364 | 31562448 |
Miosis | 52.69 | 11.04 | 81 | 73451 | 8489 | 31615323 |
Parkinsonism | 52.42 | 11.04 | 76 | 73456 | 7560 | 31616252 |
Hallucination, visual | 52.08 | 11.04 | 114 | 73418 | 15680 | 31608132 |
Plasma cell myeloma | 51.31 | 11.04 | 34 | 73498 | 56497 | 31567315 |
Cough | 51.25 | 11.04 | 152 | 73380 | 134662 | 31489150 |
Sexual dysfunction | 50.94 | 11.04 | 66 | 73466 | 5902 | 31617910 |
Thrombocytopenia | 50.70 | 11.04 | 166 | 73366 | 142581 | 31481231 |
Death | 50.68 | 11.04 | 564 | 72968 | 360005 | 31263807 |
Stress cardiomyopathy | 50.29 | 11.04 | 38 | 73494 | 1752 | 31622060 |
Renal impairment | 49.80 | 11.04 | 77 | 73455 | 86272 | 31537540 |
Feelings of worthlessness | 49.34 | 11.04 | 20 | 73512 | 258 | 31623554 |
Infection | 49.25 | 11.04 | 71 | 73461 | 81860 | 31541952 |
Congenital megaureter | 49.13 | 11.04 | 17 | 73515 | 136 | 31623676 |
Confusional state | 48.73 | 11.04 | 498 | 73034 | 132836 | 31490976 |
Septic shock | 48.61 | 11.04 | 49 | 73483 | 66109 | 31557703 |
Pruritus | 48.39 | 11.04 | 140 | 73392 | 125027 | 31498785 |
Haemoglobin decreased | 48.10 | 11.04 | 120 | 73412 | 112555 | 31511257 |
Neonatal tachypnoea | 47.09 | 11.04 | 17 | 73515 | 156 | 31623656 |
Neuropathy peripheral | 47.02 | 11.04 | 64 | 73468 | 75585 | 31548227 |
Drug screen positive | 46.78 | 11.04 | 51 | 73481 | 3801 | 31620011 |
Akathisia | 46.64 | 11.04 | 70 | 73462 | 7183 | 31616629 |
Respiratory failure | 46.53 | 11.04 | 104 | 73428 | 101345 | 31522467 |
Panic attack | 46.29 | 11.04 | 77 | 73455 | 8626 | 31615186 |
Cytomegalovirus infection | 45.49 | 11.04 | 3 | 73529 | 24704 | 31599108 |
Maternal drugs affecting foetus | 44.51 | 11.04 | 50 | 73482 | 3853 | 31619959 |
Impulsive behaviour | 44.26 | 11.04 | 37 | 73495 | 1976 | 31621836 |
Feeling jittery | 44.12 | 11.04 | 49 | 73483 | 3728 | 31620084 |
Cardiac failure congestive | 43.70 | 11.04 | 73 | 73459 | 79314 | 31544498 |
Hypomania | 42.88 | 11.04 | 38 | 73494 | 2197 | 31621615 |
Feeling abnormal | 42.84 | 11.04 | 252 | 73280 | 56750 | 31567062 |
Clonus | 42.79 | 11.04 | 40 | 73492 | 2479 | 31621333 |
Erythema | 42.37 | 11.04 | 76 | 73456 | 80329 | 31543483 |
Cyanosis neonatal | 41.78 | 11.04 | 18 | 73514 | 273 | 31623539 |
Neuroleptic malignant syndrome | 40.80 | 11.04 | 108 | 73424 | 16761 | 31607051 |
Psychomotor hyperactivity | 40.53 | 11.04 | 73 | 73459 | 8714 | 31615098 |
Tachycardia | 40.45 | 11.04 | 309 | 73223 | 75898 | 31547914 |
Gastrointestinal haemorrhage | 40.03 | 11.04 | 82 | 73450 | 82467 | 31541345 |
Antidepressant drug level increased | 39.93 | 11.04 | 14 | 73518 | 117 | 31623695 |
Pancytopenia | 39.63 | 11.04 | 90 | 73442 | 87226 | 31536586 |
Restless legs syndrome | 39.10 | 11.04 | 67 | 73465 | 7689 | 31616123 |
Sleep disorder | 38.87 | 11.04 | 142 | 73390 | 26206 | 31597606 |
Urinary retention | 38.68 | 11.04 | 168 | 73364 | 33557 | 31590255 |
Memory impairment | 38.56 | 11.04 | 183 | 73349 | 37947 | 31585865 |
Abnormal behaviour | 38.22 | 11.04 | 132 | 73400 | 23696 | 31600116 |
Bone marrow failure | 38.20 | 11.04 | 9 | 73523 | 27999 | 31595813 |
Stomatitis | 38.17 | 11.04 | 22 | 73510 | 39416 | 31584396 |
Atrial fibrillation | 37.88 | 11.04 | 136 | 73396 | 113647 | 31510165 |
Blood creatinine increased | 37.13 | 11.04 | 96 | 73436 | 88982 | 31534830 |
Electrocardiogram QRS complex prolonged | 36.46 | 11.04 | 47 | 73485 | 4182 | 31619630 |
Social anxiety disorder | 35.97 | 11.04 | 16 | 73516 | 263 | 31623549 |
Oedema peripheral | 34.79 | 11.04 | 134 | 73398 | 109705 | 31514107 |
Self-injurious ideation | 34.54 | 11.04 | 29 | 73503 | 1558 | 31622254 |
Tremor neonatal | 33.65 | 11.04 | 17 | 73515 | 376 | 31623436 |
Tardive dyskinesia | 33.41 | 11.04 | 52 | 73480 | 5507 | 31618305 |
Product substitution issue | 33.30 | 11.04 | 70 | 73462 | 9362 | 31614450 |
Muscle rigidity | 33.27 | 11.04 | 72 | 73460 | 9825 | 31613987 |
Neonatal toxicity | 33.20 | 11.04 | 9 | 73523 | 27 | 31623785 |
Poor weight gain neonatal | 32.49 | 11.04 | 8 | 73524 | 14 | 31623798 |
Macrophages increased | 32.47 | 11.04 | 13 | 73519 | 162 | 31623650 |
Persecutory delusion | 31.85 | 11.04 | 33 | 73499 | 2319 | 31621493 |
Neonatal disorder | 31.67 | 11.04 | 21 | 73511 | 785 | 31623027 |
Electric shock | 31.64 | 11.04 | 12 | 73520 | 128 | 31623684 |
Cardio-respiratory arrest | 31.62 | 11.04 | 217 | 73315 | 51509 | 31572303 |
Infusion related reaction | 31.55 | 11.04 | 39 | 73493 | 48016 | 31575796 |
Pleural effusion | 31.02 | 11.04 | 81 | 73451 | 74839 | 31548973 |
Suicidal behaviour | 30.82 | 11.04 | 26 | 73506 | 1406 | 31622406 |
Obsessive-compulsive disorder | 30.82 | 11.04 | 47 | 73485 | 4890 | 31618922 |
Poor quality sleep | 30.69 | 11.04 | 60 | 73472 | 7618 | 31616194 |
Hyperthermia | 30.50 | 11.04 | 70 | 73462 | 9934 | 31613878 |
Encephalopathy neonatal | 30.46 | 11.04 | 9 | 73523 | 40 | 31623772 |
Logorrhoea | 30.44 | 11.04 | 32 | 73500 | 2287 | 31621525 |
Apgar score low | 30.34 | 11.04 | 21 | 73511 | 843 | 31622969 |
Paranoia | 30.16 | 11.04 | 72 | 73460 | 10483 | 31613329 |
Ejaculation disorder | 30.01 | 11.04 | 22 | 73510 | 968 | 31622844 |
Arthralgia | 29.88 | 11.04 | 217 | 73315 | 151207 | 31472605 |
International normalised ratio increased | 29.38 | 11.04 | 37 | 73495 | 45186 | 31578626 |
Thinking abnormal | 29.23 | 11.04 | 49 | 73483 | 5524 | 31618288 |
Homicidal ideation | 29.21 | 11.04 | 33 | 73499 | 2558 | 31621254 |
Chronic kidney disease | 29.19 | 11.04 | 27 | 73505 | 37948 | 31585864 |
Normal pressure hydrocephalus | 29.18 | 11.04 | 12 | 73520 | 161 | 31623651 |
Hypospadias | 29.03 | 11.04 | 36 | 73496 | 3080 | 31620732 |
Muscle twitching | 28.96 | 11.04 | 61 | 73471 | 8169 | 31615643 |
Sleep apnoea syndrome | 28.85 | 11.04 | 102 | 73430 | 18523 | 31605289 |
Libido decreased | 28.79 | 11.04 | 43 | 73489 | 4393 | 31619419 |
Prostate cancer | 28.59 | 11.04 | 27 | 73505 | 37574 | 31586238 |
Dysphoria | 28.57 | 11.04 | 30 | 73502 | 2142 | 31621670 |
Cognitive disorder | 28.46 | 11.04 | 124 | 73408 | 24799 | 31599013 |
Mood altered | 28.38 | 11.04 | 61 | 73471 | 8285 | 31615527 |
Extrapyramidal disorder | 28.07 | 11.04 | 75 | 73457 | 11703 | 31612109 |
White blood cell count decreased | 28.07 | 11.04 | 106 | 73426 | 87292 | 31536520 |
Micturition urgency | 28.04 | 11.04 | 49 | 73483 | 5711 | 31618101 |
Implant site extravasation | 27.96 | 11.04 | 15 | 73517 | 377 | 31623435 |
Abnormal dreams | 27.75 | 11.04 | 55 | 73477 | 7053 | 31616759 |
Apathy | 27.56 | 11.04 | 52 | 73480 | 6430 | 31617382 |
Thermophobia | 27.55 | 11.04 | 9 | 73523 | 59 | 31623753 |
Generalised tonic-clonic seizure | 27.38 | 11.04 | 105 | 73427 | 19826 | 31603986 |
Multiple organ dysfunction syndrome | 27.28 | 11.04 | 75 | 73457 | 68128 | 31555684 |
Disseminated intravascular coagulation | 27.23 | 11.04 | 7 | 73525 | 20530 | 31603282 |
Mental impairment | 27.21 | 11.04 | 65 | 73467 | 9467 | 31614345 |
Wrong dose | 27.09 | 11.04 | 16 | 73516 | 486 | 31623326 |
Liver disorder | 26.77 | 11.04 | 18 | 73514 | 29689 | 31594123 |
Decreased interest | 26.65 | 11.04 | 29 | 73503 | 2156 | 31621656 |
Dissociation | 26.56 | 11.04 | 23 | 73509 | 1289 | 31622523 |
Alcoholism | 26.56 | 11.04 | 36 | 73496 | 3363 | 31620449 |
Hepatic function abnormal | 26.49 | 11.04 | 34 | 73498 | 41188 | 31582624 |
Disorientation | 26.46 | 11.04 | 141 | 73391 | 30603 | 31593209 |
Acoustic stimulation tests abnormal | 26.34 | 11.04 | 9 | 73523 | 69 | 31623743 |
Epilepsy | 25.82 | 11.04 | 107 | 73425 | 20934 | 31602878 |
Substance abuser | 25.54 | 11.04 | 10 | 73522 | 117 | 31623695 |
Premature baby | 25.50 | 11.04 | 96 | 73436 | 17970 | 31605842 |
Euphoric mood | 25.46 | 11.04 | 43 | 73489 | 4877 | 31618935 |
Loss of consciousness | 25.44 | 11.04 | 283 | 73249 | 77072 | 31546740 |
Neonatal testicular torsion | 25.34 | 11.04 | 5 | 73527 | 0 | 31623812 |
COVID-19 | 25.28 | 11.04 | 56 | 73476 | 54765 | 31569047 |
Eosinophilic myocarditis | 25.21 | 11.04 | 15 | 73517 | 462 | 31623350 |
Potentiating drug interaction | 25.18 | 11.04 | 41 | 73491 | 4512 | 31619300 |
Stevens-Johnson syndrome | 24.87 | 11.04 | 5 | 73527 | 17367 | 31606445 |
Muscle mass | 24.76 | 11.04 | 12 | 73520 | 242 | 31623570 |
Mucosal inflammation | 24.71 | 11.04 | 26 | 73506 | 34401 | 31589411 |
Pneumocystis jirovecii pneumonia | 24.62 | 11.04 | 6 | 73526 | 18245 | 31605567 |
Cerebral infarction | 24.42 | 11.04 | 15 | 73517 | 25962 | 31597850 |
Weight increased | 24.41 | 11.04 | 297 | 73235 | 82650 | 31541162 |
Pyramidal tract syndrome | 24.40 | 11.04 | 11 | 73521 | 187 | 31623625 |
Joint swelling | 24.29 | 11.04 | 55 | 73477 | 53376 | 31570436 |
Tearfulness | 24.25 | 11.04 | 26 | 73506 | 1901 | 31621911 |
Multiple drug therapy | 24.07 | 11.04 | 14 | 73518 | 413 | 31623399 |
Alopecia | 23.95 | 11.04 | 9 | 73523 | 20686 | 31603126 |
Arachnoid cyst | 23.93 | 11.04 | 11 | 73521 | 196 | 31623616 |
Reduced facial expression | 23.89 | 11.04 | 18 | 73514 | 826 | 31622986 |
Foetal malnutrition | 23.80 | 11.04 | 8 | 73524 | 58 | 31623754 |
Neonatal respiratory failure | 23.66 | 11.04 | 13 | 73519 | 343 | 31623469 |
Cardiac failure | 23.43 | 11.04 | 111 | 73421 | 85842 | 31537970 |
Amnesia | 23.42 | 11.04 | 112 | 73420 | 23290 | 31600522 |
Priapism | 23.40 | 11.04 | 40 | 73492 | 4580 | 31619232 |
Testicular atrophy | 23.39 | 11.04 | 15 | 73517 | 529 | 31623283 |
Renal failure | 23.24 | 11.04 | 179 | 73353 | 123151 | 31500661 |
Pressure of speech | 22.83 | 11.04 | 14 | 73518 | 456 | 31623356 |
Anaphylactic reaction | 22.73 | 11.04 | 21 | 73511 | 29532 | 31594280 |
Inappropriate antidiuretic hormone secretion | 22.73 | 11.04 | 68 | 73464 | 11319 | 31612493 |
Head circumference abnormal | 22.70 | 11.04 | 7 | 73525 | 37 | 31623775 |
Mood swings | 22.69 | 11.04 | 52 | 73480 | 7372 | 31616440 |
Paraesthesia | 22.67 | 11.04 | 214 | 73318 | 55857 | 31567955 |
Acute myocardial infarction | 22.55 | 11.04 | 53 | 73479 | 50770 | 31573042 |
Pulmonary contusion | 22.54 | 11.04 | 7 | 73525 | 38 | 31623774 |
Depersonalisation/derealisation disorder | 22.38 | 11.04 | 15 | 73517 | 571 | 31623241 |
Product residue present | 22.31 | 11.04 | 29 | 73503 | 2601 | 31621211 |
Dry mouth | 22.30 | 11.04 | 114 | 73418 | 24344 | 31599468 |
Phaeochromocytoma malignant | 22.30 | 11.04 | 8 | 73524 | 72 | 31623740 |
Blood ethanol increased | 22.26 | 11.04 | 14 | 73518 | 477 | 31623335 |
Depression suicidal | 22.19 | 11.04 | 23 | 73509 | 1617 | 31622195 |
Renal aplasia | 22.19 | 11.04 | 16 | 73516 | 686 | 31623126 |
Pneumonitis | 22.16 | 11.04 | 23 | 73509 | 30629 | 31593183 |
Salivary hypersecretion | 22.10 | 11.04 | 53 | 73479 | 7739 | 31616073 |
Kidney duplex | 22.01 | 11.04 | 13 | 73519 | 395 | 31623417 |
External auditory canal atresia | 21.97 | 11.04 | 10 | 73522 | 174 | 31623638 |
Fall | 21.95 | 11.04 | 576 | 72956 | 185513 | 31438299 |
Iris coloboma | 21.89 | 11.04 | 6 | 73526 | 19 | 31623793 |
Splenomegaly | 21.81 | 11.04 | 3 | 73529 | 13746 | 31610066 |
Toxic cardiomyopathy | 21.70 | 11.04 | 11 | 73521 | 245 | 31623567 |
Retinal coloboma | 21.66 | 11.04 | 6 | 73526 | 20 | 31623792 |
Blood bilirubin increased | 21.54 | 11.04 | 30 | 73502 | 35106 | 31588706 |
Neonatal behavioural syndrome | 21.47 | 11.04 | 9 | 73523 | 127 | 31623685 |
Hangover | 21.44 | 11.04 | 18 | 73514 | 967 | 31622845 |
Myelodysplastic syndrome | 21.25 | 11.04 | 9 | 73523 | 19242 | 31604570 |
Coma scale abnormal | 21.23 | 11.04 | 34 | 73498 | 3689 | 31620123 |
Myocardial fibrosis | 21.17 | 11.04 | 19 | 73513 | 1117 | 31622695 |
Abulia | 21.09 | 11.04 | 14 | 73518 | 524 | 31623288 |
Neonatal respiratory distress | 21.07 | 11.04 | 14 | 73518 | 525 | 31623287 |
Hypervigilance | 20.98 | 11.04 | 9 | 73523 | 135 | 31623677 |
Coagulation disorder neonatal | 20.81 | 11.04 | 6 | 73526 | 24 | 31623788 |
Histamine level increased | 20.68 | 11.04 | 7 | 73525 | 52 | 31623760 |
Electrocardiogram QT shortened | 20.45 | 11.04 | 9 | 73523 | 144 | 31623668 |
Bipolar II disorder | 20.43 | 11.04 | 6 | 73526 | 26 | 31623786 |
Loose associations | 20.34 | 11.04 | 7 | 73525 | 55 | 31623757 |
Tachycardia foetal | 20.33 | 11.04 | 12 | 73520 | 364 | 31623448 |
Microcephaly | 20.33 | 11.04 | 16 | 73516 | 784 | 31623028 |
Antidepressant discontinuation syndrome | 20.27 | 11.04 | 4 | 73528 | 0 | 31623812 |
External ear disorder | 20.25 | 11.04 | 6 | 73526 | 27 | 31623785 |
Foetal hypokinesia | 20.10 | 11.04 | 12 | 73520 | 372 | 31623440 |
Drug hypersensitivity | 20.09 | 11.04 | 257 | 73275 | 72342 | 31551470 |
Hepatocellular injury | 20.05 | 11.04 | 101 | 73431 | 21443 | 31602369 |
Gun shot wound | 19.80 | 11.04 | 18 | 73514 | 1076 | 31622736 |
Affective disorder | 19.79 | 11.04 | 33 | 73499 | 3703 | 31620109 |
Persistent depressive disorder | 19.69 | 11.04 | 11 | 73521 | 300 | 31623512 |
Metabolic syndrome | 19.51 | 11.04 | 21 | 73511 | 1542 | 31622270 |
Poor sucking reflex | 19.43 | 11.04 | 11 | 73521 | 308 | 31623504 |
Bronchopulmonary aspergillosis | 19.36 | 11.04 | 4 | 73528 | 13630 | 31610182 |
Foaming at mouth | 19.27 | 11.04 | 15 | 73517 | 723 | 31623089 |
Blood cholesterol increased | 19.25 | 11.04 | 84 | 73448 | 16809 | 31607003 |
Personality disorder | 19.21 | 11.04 | 18 | 73514 | 1119 | 31622693 |
Violence-related symptom | 19.07 | 11.04 | 13 | 73519 | 509 | 31623303 |
Tumour lysis syndrome | 19.00 | 11.04 | 6 | 73526 | 15379 | 31608433 |
Penoscrotal fusion | 18.97 | 11.04 | 5 | 73527 | 13 | 31623799 |
Condition aggravated | 18.85 | 11.04 | 506 | 73026 | 163503 | 31460309 |
Rhabdomyolysis | 18.84 | 11.04 | 228 | 73304 | 63353 | 31560459 |
Bruxism | 18.79 | 11.04 | 21 | 73511 | 1609 | 31622203 |
Synovitis | 18.75 | 11.04 | 3 | 73529 | 12280 | 31611532 |
Haematoma | 18.74 | 11.04 | 17 | 73515 | 24122 | 31599690 |
Lymphadenopathy | 18.44 | 11.04 | 20 | 73512 | 26101 | 31597711 |
Visual evoked potentials abnormal | 18.43 | 11.04 | 7 | 73525 | 75 | 31623737 |
Urticaria | 18.30 | 11.04 | 70 | 73462 | 57447 | 31566365 |
Loss of libido | 18.16 | 11.04 | 25 | 73507 | 2370 | 31621442 |
Physical deconditioning | 18.11 | 11.04 | 16 | 73516 | 921 | 31622891 |
Nephrolithiasis | 18.09 | 11.04 | 117 | 73415 | 27222 | 31596590 |
Bradykinesia | 18.06 | 11.04 | 31 | 73501 | 3561 | 31620251 |
Hydrops foetalis | 18.06 | 11.04 | 12 | 73520 | 450 | 31623362 |
Dyskinesia neonatal | 18.04 | 11.04 | 4 | 73528 | 3 | 31623809 |
Patent ductus arteriosus | 17.99 | 11.04 | 29 | 73503 | 3164 | 31620648 |
Gastrointestinal hypermotility | 17.90 | 11.04 | 8 | 73524 | 133 | 31623679 |
Hypokalaemia | 17.83 | 11.04 | 64 | 73468 | 53510 | 31570302 |
Neutrophil count decreased | 17.82 | 11.04 | 52 | 73480 | 46342 | 31577470 |
Rash maculo-papular | 17.81 | 11.04 | 20 | 73512 | 25699 | 31598113 |
Thrombosis | 17.79 | 11.04 | 50 | 73482 | 45101 | 31578711 |
Contraindicated product administered | 17.79 | 11.04 | 12 | 73520 | 19760 | 31604052 |
Drug screen false positive | 17.73 | 11.04 | 14 | 73518 | 689 | 31623123 |
Haematuria | 17.73 | 11.04 | 52 | 73480 | 46262 | 31577550 |
Forearm fracture | 17.72 | 11.04 | 7 | 73525 | 84 | 31623728 |
Hypoxia | 17.49 | 11.04 | 59 | 73473 | 50254 | 31573558 |
Emotional disorder | 17.43 | 11.04 | 38 | 73494 | 5211 | 31618601 |
Sleep-related eating disorder | 17.26 | 11.04 | 10 | 73522 | 293 | 31623519 |
Acute myeloid leukaemia | 17.25 | 11.04 | 11 | 73521 | 18661 | 31605151 |
Hyperkalaemia | 17.01 | 11.04 | 84 | 73448 | 64267 | 31559545 |
Tubulointerstitial nephritis | 16.94 | 11.04 | 11 | 73521 | 18485 | 31605327 |
Cerebellar syndrome | 16.89 | 11.04 | 23 | 73509 | 2158 | 31621654 |
Oedema | 16.87 | 11.04 | 47 | 73485 | 42514 | 31581298 |
Enuresis | 16.86 | 11.04 | 23 | 73509 | 2161 | 31621651 |
Congenital central nervous system anomaly | 16.51 | 11.04 | 12 | 73520 | 521 | 31623291 |
Decreased appetite | 16.50 | 11.04 | 253 | 73279 | 152964 | 31470848 |
Cerebral ventricle dilatation | 16.50 | 11.04 | 15 | 73517 | 897 | 31622915 |
Social avoidant behaviour | 16.48 | 11.04 | 27 | 73505 | 2986 | 31620826 |
Pulmonary artery stenosis | 16.46 | 11.04 | 9 | 73523 | 235 | 31623577 |
Male orgasmic disorder | 16.44 | 11.04 | 7 | 73525 | 103 | 31623709 |
Myelosuppression | 16.43 | 11.04 | 7 | 73525 | 14913 | 31608899 |
Heat stroke | 16.40 | 11.04 | 15 | 73517 | 904 | 31622908 |
Tinnitus | 16.36 | 11.04 | 78 | 73454 | 16197 | 31607615 |
Suspected suicide | 16.30 | 11.04 | 32 | 73500 | 4075 | 31619737 |
Blunted affect | 16.30 | 11.04 | 10 | 73522 | 326 | 31623486 |
C-reactive protein increased | 16.27 | 11.04 | 58 | 73474 | 48592 | 31575220 |
Micturition disorder | 16.26 | 11.04 | 22 | 73510 | 2051 | 31621761 |
Action tremor | 16.25 | 11.04 | 6 | 73526 | 59 | 31623753 |
Delirium | 16.20 | 11.04 | 157 | 73375 | 41264 | 31582548 |
Catatonia | 16.15 | 11.04 | 35 | 73497 | 4779 | 31619033 |
Cor pulmonale acute | 16.06 | 11.04 | 9 | 73523 | 247 | 31623565 |
Peripheral swelling | 16.04 | 11.04 | 92 | 73440 | 67773 | 31556039 |
Floppy infant | 16.02 | 11.04 | 7 | 73525 | 110 | 31623702 |
Otospondylomegaepiphyseal dysplasia | 16.02 | 11.04 | 7 | 73525 | 110 | 31623702 |
Diarrhoea neonatal | 15.97 | 11.04 | 5 | 73527 | 28 | 31623784 |
Hyponatraemic coma | 15.97 | 11.04 | 5 | 73527 | 28 | 31623784 |
Respiratory arrest | 15.94 | 11.04 | 110 | 73422 | 26147 | 31597665 |
Mental disorder | 15.92 | 11.04 | 69 | 73463 | 13765 | 31610047 |
Sleep paralysis | 15.92 | 11.04 | 8 | 73524 | 175 | 31623637 |
Palmar-plantar erythrodysaesthesia syndrome | 15.91 | 11.04 | 8 | 73524 | 15475 | 31608337 |
Physical assault | 15.90 | 11.04 | 16 | 73516 | 1086 | 31622726 |
Food aversion | 15.90 | 11.04 | 10 | 73522 | 341 | 31623471 |
Crying | 15.80 | 11.04 | 38 | 73494 | 5559 | 31618253 |
Product used for unknown indication | 15.75 | 11.04 | 14 | 73518 | 813 | 31622999 |
Ascites | 15.73 | 11.04 | 46 | 73486 | 40967 | 31582845 |
Gambling disorder | 15.72 | 11.04 | 19 | 73513 | 1583 | 31622229 |
Balance disorder | 15.71 | 11.04 | 144 | 73388 | 37278 | 31586534 |
Tricuspid valve sclerosis | 15.68 | 11.04 | 5 | 73527 | 30 | 31623782 |
Hospitalisation | 15.60 | 11.04 | 61 | 73471 | 49746 | 31574066 |
Cerebral microangiopathy | 15.59 | 11.04 | 8 | 73524 | 183 | 31623629 |
Coagulation factor VII level decreased | 15.58 | 11.04 | 7 | 73525 | 118 | 31623694 |
CADASIL | 15.58 | 11.04 | 6 | 73526 | 67 | 31623745 |
Food craving | 15.54 | 11.04 | 10 | 73522 | 355 | 31623457 |
Derealisation | 15.51 | 11.04 | 12 | 73520 | 573 | 31623239 |
Pseudohyponatraemia | 15.50 | 11.04 | 6 | 73526 | 68 | 31623744 |
Infantile vomiting | 15.41 | 11.04 | 5 | 73527 | 32 | 31623780 |
Unemployment | 15.41 | 11.04 | 5 | 73527 | 32 | 31623780 |
Influenza | 15.39 | 11.04 | 52 | 73480 | 44273 | 31579539 |
Magnetic resonance imaging spinal abnormal | 15.26 | 11.04 | 6 | 73526 | 71 | 31623741 |
Selective mutism | 15.26 | 11.04 | 6 | 73526 | 71 | 31623741 |
Nervousness | 15.26 | 11.04 | 61 | 73471 | 11739 | 31612073 |
Kleptomania | 15.21 | 11.04 | 3 | 73529 | 0 | 31623812 |
Onychomycosis | 15.20 | 11.04 | 22 | 73510 | 2184 | 31621628 |
Meningocele | 15.15 | 11.04 | 5 | 73527 | 34 | 31623778 |
Accidental death | 15.12 | 11.04 | 22 | 73510 | 2195 | 31621617 |
Catecholamines urine increased | 15.01 | 11.04 | 4 | 73528 | 11 | 31623801 |
Dizziness | 14.96 | 11.04 | 584 | 72948 | 198563 | 31425249 |
Laboratory test abnormal | 14.91 | 11.04 | 13 | 73519 | 18801 | 31605011 |
Neoplasm progression | 14.89 | 11.04 | 15 | 73517 | 20257 | 31603555 |
Toxic epidermal necrolysis | 14.86 | 11.04 | 14 | 73518 | 19510 | 31604302 |
Norepinephrine increased | 14.76 | 11.04 | 4 | 73528 | 12 | 31623800 |
Urinary straining | 14.76 | 11.04 | 4 | 73528 | 12 | 31623800 |
Pneumonia bacterial | 14.66 | 11.04 | 3 | 73529 | 10293 | 31613519 |
Food interaction | 14.64 | 11.04 | 14 | 73518 | 893 | 31622919 |
Urinary incontinence | 14.60 | 11.04 | 79 | 73453 | 17241 | 31606571 |
Tachyphrenia | 14.58 | 11.04 | 16 | 73516 | 1201 | 31622611 |
Panic disorder | 14.53 | 11.04 | 16 | 73516 | 1206 | 31622606 |
Depressive symptom | 14.45 | 11.04 | 21 | 73511 | 2093 | 31621719 |
Upper respiratory tract infection | 14.44 | 11.04 | 29 | 73503 | 29393 | 31594419 |
Rebound effect | 14.40 | 11.04 | 23 | 73509 | 2490 | 31621322 |
Drug reaction with eosinophilia and systemic symptoms | 14.38 | 11.04 | 30 | 73502 | 29988 | 31593824 |
Congestive cardiomyopathy | 14.22 | 11.04 | 42 | 73490 | 6940 | 31616872 |
Peritonitis | 14.20 | 11.04 | 9 | 73523 | 15318 | 31608494 |
Ex-drug abuser | 14.18 | 11.04 | 7 | 73525 | 147 | 31623665 |
Blepharospasm | 14.11 | 11.04 | 15 | 73517 | 1086 | 31622726 |
Laryngomalacia | 14.07 | 11.04 | 9 | 73523 | 316 | 31623496 |
Impulse-control disorder | 13.96 | 11.04 | 16 | 73516 | 1260 | 31622552 |
Prescribed overdose | 13.94 | 11.04 | 50 | 73482 | 9142 | 31614670 |
Skull fractured base | 13.93 | 11.04 | 7 | 73525 | 153 | 31623659 |
Ventricular septal defect | 13.81 | 11.04 | 28 | 73504 | 3649 | 31620163 |
Rhinorrhoea | 13.76 | 11.04 | 20 | 73512 | 22992 | 31600820 |
Affect lability | 13.76 | 11.04 | 27 | 73505 | 3438 | 31620374 |
Anal stenosis | 13.73 | 11.04 | 7 | 73525 | 158 | 31623654 |
Radiation inflammation | 13.66 | 11.04 | 11 | 73521 | 557 | 31623255 |
Product dose omission issue | 13.64 | 11.04 | 168 | 73364 | 105418 | 31518394 |
Bradyphrenia | 13.63 | 11.04 | 31 | 73501 | 4373 | 31619439 |
Limited symptom panic attack | 13.56 | 11.04 | 5 | 73527 | 49 | 31623763 |
Psoriasis | 13.52 | 11.04 | 59 | 73473 | 46660 | 31577152 |
Cerebral disorder | 13.50 | 11.04 | 22 | 73510 | 2423 | 31621389 |
Head discomfort | 13.49 | 11.04 | 28 | 73504 | 3711 | 31620101 |
Abdominal distension | 13.48 | 11.04 | 66 | 73466 | 50618 | 31573194 |
Diastolic hypotension | 13.47 | 11.04 | 5 | 73527 | 50 | 31623762 |
Sexually inappropriate behaviour | 13.46 | 11.04 | 10 | 73522 | 449 | 31623363 |
Congenital skin dimples | 13.41 | 11.04 | 7 | 73525 | 166 | 31623646 |
Withdrawal catatonia | 13.41 | 11.04 | 6 | 73526 | 100 | 31623712 |
Opisthotonus | 13.41 | 11.04 | 10 | 73522 | 452 | 31623360 |
Central nervous system inflammation | 13.36 | 11.04 | 6 | 73526 | 101 | 31623711 |
Congenital hydronephrosis | 13.35 | 11.04 | 12 | 73520 | 707 | 31623105 |
Leukopenia | 13.34 | 11.04 | 79 | 73453 | 57749 | 31566063 |
Muscle necrosis | 13.32 | 11.04 | 13 | 73519 | 850 | 31622962 |
Chest discomfort | 13.30 | 11.04 | 64 | 73468 | 49305 | 31574507 |
Blood glucose increased | 13.28 | 11.04 | 85 | 73447 | 60998 | 31562814 |
Lip pruritus | 13.13 | 11.04 | 3 | 73529 | 3 | 31623809 |
Nonspecific reaction | 13.12 | 11.04 | 15 | 73517 | 1178 | 31622634 |
Inhibitory drug interaction | 13.08 | 11.04 | 17 | 73515 | 1525 | 31622287 |
Blood urea increased | 13.07 | 11.04 | 30 | 73502 | 28982 | 31594830 |
Muscle tightness | 13.05 | 11.04 | 31 | 73501 | 4498 | 31619314 |
Urine output decreased | 13.03 | 11.04 | 3 | 73529 | 9483 | 31614329 |
Tunnel vision | 12.88 | 11.04 | 10 | 73522 | 480 | 31623332 |
Heart rate increased | 12.87 | 11.04 | 149 | 73383 | 40961 | 31582851 |
Fungal infection | 12.86 | 11.04 | 9 | 73523 | 14542 | 31609270 |
Sleep terror | 12.82 | 11.04 | 12 | 73520 | 745 | 31623067 |
Vertebral foraminal stenosis | 12.77 | 11.04 | 10 | 73522 | 486 | 31623326 |
Therapeutic response unexpected | 12.77 | 11.04 | 48 | 73484 | 8976 | 31614836 |
Renal disorder | 12.76 | 11.04 | 22 | 73510 | 23623 | 31600189 |
Hypotonia | 12.75 | 11.04 | 41 | 73491 | 7092 | 31616720 |
Insulin resistance | 12.73 | 11.04 | 11 | 73521 | 615 | 31623197 |
Conjunctivitis viral | 12.66 | 11.04 | 5 | 73527 | 60 | 31623752 |
Blood creatine phosphokinase increased | 12.64 | 11.04 | 151 | 73381 | 41823 | 31581989 |
Pre-existing condition improved | 12.60 | 11.04 | 21 | 73511 | 2356 | 31621456 |
Dissociative identity disorder | 12.55 | 11.04 | 4 | 73528 | 24 | 31623788 |
Sclerodactylia | 12.55 | 11.04 | 4 | 73528 | 24 | 31623788 |
Double inlet left ventricle | 12.55 | 11.04 | 4 | 73528 | 24 | 31623788 |
Dysgraphia | 12.54 | 11.04 | 20 | 73512 | 2163 | 31621649 |
Antineutrophil cytoplasmic antibody positive | 12.53 | 11.04 | 11 | 73521 | 628 | 31623184 |
Dyspnoea exertional | 12.52 | 11.04 | 47 | 73485 | 38790 | 31585022 |
Deep vein thrombosis | 12.46 | 11.04 | 86 | 73446 | 60650 | 31563162 |
Hypersomnia | 12.45 | 11.04 | 55 | 73477 | 11064 | 31612748 |
Cerebrovascular accident | 12.44 | 11.04 | 121 | 73411 | 79363 | 31544449 |
Convulsive threshold lowered | 12.44 | 11.04 | 10 | 73522 | 505 | 31623307 |
Haemorrhage | 12.38 | 11.04 | 62 | 73470 | 47272 | 31576540 |
Onychophagia | 12.37 | 11.04 | 5 | 73527 | 64 | 31623748 |
Obstructive airways disorder | 12.34 | 11.04 | 7 | 73525 | 12657 | 31611155 |
Distributive shock | 12.33 | 11.04 | 14 | 73518 | 1091 | 31622721 |
Fatigue | 12.32 | 11.04 | 644 | 72888 | 334562 | 31289250 |
Hepatic failure | 12.31 | 11.04 | 37 | 73495 | 32665 | 31591147 |
Sensory disturbance | 12.12 | 11.04 | 35 | 73497 | 5712 | 31618100 |
Gastric infection | 12.10 | 11.04 | 14 | 73518 | 1114 | 31622698 |
Cerebellar haematoma | 12.08 | 11.04 | 7 | 73525 | 205 | 31623607 |
Dehydration | 12.04 | 11.04 | 199 | 73333 | 118912 | 31504900 |
Exposure via breast milk | 12.03 | 11.04 | 18 | 73514 | 1842 | 31621970 |
Tryptase increased | 12.02 | 11.04 | 7 | 73525 | 207 | 31623605 |
Chills | 11.98 | 11.04 | 112 | 73420 | 74038 | 31549774 |
Candida infection | 11.98 | 11.04 | 12 | 73520 | 16246 | 31607566 |
Wheezing | 11.97 | 11.04 | 43 | 73489 | 35943 | 31587869 |
Necrotising ulcerative gingivostomatitis | 11.97 | 11.04 | 5 | 73527 | 70 | 31623742 |
Dysphemia | 11.94 | 11.04 | 16 | 73516 | 1478 | 31622334 |
Magical thinking | 11.92 | 11.04 | 3 | 73529 | 6 | 31623806 |
Congenital ureterocele | 11.92 | 11.04 | 3 | 73529 | 6 | 31623806 |
Central nervous system stimulation | 11.92 | 11.04 | 3 | 73529 | 6 | 31623806 |
Hypersensitivity | 11.90 | 11.04 | 78 | 73454 | 55665 | 31568147 |
Rectal fissure | 11.90 | 11.04 | 8 | 73524 | 306 | 31623506 |
Sinus tachycardia | 11.85 | 11.04 | 70 | 73462 | 15779 | 31608033 |
Hypogonadism | 11.84 | 11.04 | 18 | 73514 | 1867 | 31621945 |
Gonadotrophin deficiency | 11.78 | 11.04 | 4 | 73528 | 30 | 31623782 |
Obsessive-compulsive symptom | 11.78 | 11.04 | 6 | 73526 | 135 | 31623677 |
Accommodation disorder | 11.78 | 11.04 | 7 | 73525 | 215 | 31623597 |
Haemolytic anaemia | 11.78 | 11.04 | 4 | 73528 | 9792 | 31614020 |
Substance abuse | 11.78 | 11.04 | 40 | 73492 | 7118 | 31616694 |
Alcohol poisoning | 11.74 | 11.04 | 24 | 73508 | 3147 | 31620665 |
Spondylolisthesis | 11.64 | 11.04 | 11 | 73521 | 691 | 31623121 |
Antidepressant drug level above therapeutic | 11.64 | 11.04 | 7 | 73525 | 220 | 31623592 |
Accident at work | 11.63 | 11.04 | 11 | 73521 | 692 | 31623120 |
Implant site infection | 11.62 | 11.04 | 13 | 73519 | 997 | 31622815 |
Hepatocellular carcinoma | 11.58 | 11.04 | 3 | 73529 | 8753 | 31615059 |
Swelling | 11.54 | 11.04 | 46 | 73486 | 37312 | 31586500 |
Feeling drunk | 11.40 | 11.04 | 17 | 73515 | 1734 | 31622078 |
Flashback | 11.36 | 11.04 | 6 | 73526 | 146 | 31623666 |
Diffuse large B-cell lymphoma | 11.35 | 11.04 | 3 | 73529 | 8638 | 31615174 |
Skin exfoliation | 11.32 | 11.04 | 24 | 73508 | 23850 | 31599962 |
Full blood count decreased | 11.30 | 11.04 | 13 | 73519 | 16527 | 31607285 |
Pancreatic carcinoma | 11.27 | 11.04 | 3 | 73529 | 8597 | 31615215 |
Repetitive speech | 11.25 | 11.04 | 5 | 73527 | 82 | 31623730 |
Productive cough | 11.20 | 11.04 | 40 | 73492 | 33500 | 31590312 |
Haematochezia | 11.17 | 11.04 | 52 | 73480 | 40412 | 31583400 |
Anorgasmia | 11.15 | 11.04 | 11 | 73521 | 729 | 31623083 |
Univentricular heart | 11.15 | 11.04 | 4 | 73528 | 36 | 31623776 |
Flight of ideas | 11.11 | 11.04 | 8 | 73524 | 342 | 31623470 |
Tension headache | 11.11 | 11.04 | 15 | 73517 | 1396 | 31622416 |
Neonatal hypotension | 11.10 | 11.04 | 6 | 73526 | 153 | 31623659 |
Naevus flammeus | 11.10 | 11.04 | 6 | 73526 | 153 | 31623659 |
Saccadic eye movement | 11.07 | 11.04 | 6 | 73526 | 154 | 31623658 |
Hepatotoxicity | 11.07 | 11.04 | 17 | 73515 | 19109 | 31604703 |
Craniocerebral injury | 11.06 | 11.04 | 22 | 73510 | 2828 | 31620984 |
Small intestinal obstruction | 11.05 | 11.04 | 9 | 73523 | 13463 | 31610349 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Completed suicide | 2048.80 | 9.88 | 2863 | 199678 | 224272 | 70501631 |
Serotonin syndrome | 1488.54 | 9.88 | 1114 | 201427 | 41000 | 70684903 |
Intentional overdose | 1258.12 | 9.88 | 1477 | 201064 | 96958 | 70628945 |
Suicide attempt | 1153.11 | 9.88 | 1274 | 201267 | 78236 | 70647667 |
Toxicity to various agents | 1129.99 | 9.88 | 2996 | 199545 | 379176 | 70346727 |
Suicidal ideation | 972.67 | 9.88 | 1094 | 201447 | 68502 | 70657401 |
Drug withdrawal syndrome | 912.98 | 9.88 | 753 | 201788 | 31962 | 70693941 |
Overdose | 831.13 | 9.88 | 1627 | 200914 | 168118 | 70557785 |
Depression | 758.83 | 9.88 | 1722 | 200819 | 197252 | 70528651 |
Drug abuse | 576.15 | 9.88 | 1288 | 201253 | 145968 | 70579935 |
Poisoning deliberate | 559.88 | 9.88 | 432 | 202109 | 16628 | 70709275 |
Intentional self-injury | 530.54 | 9.88 | 548 | 201993 | 31102 | 70694801 |
Withdrawal syndrome | 492.86 | 9.88 | 472 | 202069 | 24432 | 70701471 |
Coma | 480.44 | 9.88 | 906 | 201635 | 90938 | 70634965 |
Sopor | 454.54 | 9.88 | 502 | 202039 | 30765 | 70695138 |
Anxiety | 442.17 | 9.88 | 1509 | 201032 | 218821 | 70507082 |
Drug interaction | 424.09 | 9.88 | 2179 | 200362 | 379262 | 70346641 |
Agitation | 375.37 | 9.88 | 826 | 201715 | 92549 | 70633354 |
Mydriasis | 351.96 | 9.88 | 323 | 202218 | 15830 | 70710073 |
Hyperhidrosis | 333.23 | 9.88 | 977 | 201564 | 130609 | 70595294 |
Tremor | 328.01 | 9.88 | 1084 | 201457 | 154540 | 70571363 |
Rheumatoid arthritis | 322.56 | 9.88 | 219 | 202322 | 291586 | 70434317 |
Somnolence | 304.39 | 9.88 | 1321 | 201220 | 214285 | 70511618 |
Electrocardiogram QT prolonged | 288.44 | 9.88 | 696 | 201845 | 82821 | 70643082 |
Synovitis | 274.34 | 9.88 | 26 | 202515 | 129202 | 70596701 |
Febrile neutropenia | 254.29 | 9.88 | 133 | 202408 | 204185 | 70521718 |
Depressed mood | 236.13 | 9.88 | 438 | 202103 | 43382 | 70682521 |
Joint swelling | 223.41 | 9.88 | 236 | 202305 | 252975 | 70472928 |
Seizure | 218.72 | 9.88 | 1047 | 201494 | 176915 | 70548988 |
Disturbance in attention | 217.79 | 9.88 | 418 | 202123 | 42476 | 70683427 |
Akathisia | 217.13 | 9.88 | 219 | 202322 | 12074 | 70713829 |
Nightmare | 210.37 | 9.88 | 287 | 202254 | 21869 | 70704034 |
Irritability | 207.11 | 9.88 | 383 | 202158 | 37842 | 70688061 |
Pneumonia | 206.85 | 9.88 | 938 | 201603 | 595294 | 70130609 |
Hand deformity | 201.87 | 9.88 | 11 | 202530 | 86471 | 70639432 |
Crying | 195.85 | 9.88 | 271 | 202270 | 20928 | 70704975 |
Infusion related reaction | 191.77 | 9.88 | 169 | 202372 | 197365 | 70528538 |
Contraindicated product administered | 185.44 | 9.88 | 76 | 202465 | 134536 | 70591367 |
Pyrexia | 184.01 | 9.88 | 1001 | 201540 | 605951 | 70119952 |
Major depression | 178.17 | 9.88 | 167 | 202374 | 8407 | 70717496 |
Mania | 169.95 | 9.88 | 227 | 202314 | 16947 | 70708956 |
Restlessness | 166.16 | 9.88 | 370 | 202171 | 41758 | 70684145 |
Anaemia | 165.99 | 9.88 | 593 | 201948 | 402830 | 70323073 |
Sepsis | 165.63 | 9.88 | 277 | 202264 | 244268 | 70481635 |
Rash | 163.61 | 9.88 | 826 | 201715 | 509736 | 70216167 |
Systemic lupus erythematosus | 162.14 | 9.88 | 45 | 202496 | 101857 | 70624046 |
Pericarditis | 160.26 | 9.88 | 25 | 202516 | 84680 | 70641223 |
Feeling abnormal | 159.63 | 9.88 | 816 | 201725 | 141503 | 70584400 |
Poisoning | 153 | 9.88 | 250 | 202291 | 22372 | 70703531 |
Infection | 150.99 | 9.88 | 230 | 202311 | 210555 | 70515348 |
Anger | 150.18 | 9.88 | 207 | 202334 | 15925 | 70709978 |
Off label use | 146.52 | 9.88 | 1387 | 201154 | 741673 | 69984230 |
Drug dependence | 144.07 | 9.88 | 325 | 202216 | 36996 | 70688907 |
Panic attack | 142.29 | 9.88 | 239 | 202302 | 21880 | 70704023 |
Arthropathy | 137.78 | 9.88 | 135 | 202406 | 149922 | 70575981 |
Generalised tonic-clonic seizure | 137.18 | 9.88 | 341 | 202200 | 41320 | 70684583 |
Glossodynia | 134.26 | 9.88 | 40 | 202501 | 86447 | 70639456 |
Insomnia | 134.07 | 9.88 | 1072 | 201469 | 216734 | 70509169 |
Neutropenia | 133.68 | 9.88 | 339 | 202202 | 256817 | 70469086 |
Cataplexy | 133.65 | 9.88 | 63 | 202478 | 956 | 70724947 |
Duodenal ulcer perforation | 131.35 | 9.88 | 3 | 202538 | 51109 | 70674794 |
Cardio-respiratory arrest | 130.65 | 9.88 | 602 | 201939 | 100075 | 70625828 |
Tachycardia | 127.38 | 9.88 | 832 | 201709 | 157714 | 70568189 |
Platelet count decreased | 125.19 | 9.88 | 197 | 202344 | 178025 | 70547878 |
Helicobacter infection | 124.14 | 9.88 | 9 | 202532 | 55647 | 70670256 |
Rheumatoid factor positive | 123.76 | 9.88 | 3 | 202538 | 48397 | 70677506 |
Psychomotor hyperactivity | 121.66 | 9.88 | 183 | 202358 | 15250 | 70710653 |
Drug hypersensitivity | 121.53 | 9.88 | 1214 | 201327 | 261245 | 70464658 |
Stress cardiomyopathy | 120.82 | 9.88 | 145 | 202396 | 9717 | 70716186 |
Hypersensitivity | 117.09 | 9.88 | 306 | 202235 | 229506 | 70496397 |
Altered state of consciousness | 116.73 | 9.88 | 313 | 202228 | 39709 | 70686194 |
Stomatitis | 116.38 | 9.88 | 117 | 202424 | 128394 | 70597509 |
Disease progression | 115.03 | 9.88 | 168 | 202373 | 156504 | 70569399 |
Respiratory arrest | 114.64 | 9.88 | 377 | 202164 | 53556 | 70672347 |
Homicide | 113.75 | 9.88 | 59 | 202482 | 1111 | 70724792 |
Aggression | 111.47 | 9.88 | 348 | 202193 | 48098 | 70677805 |
Muscle rigidity | 111.39 | 9.88 | 195 | 202346 | 18455 | 70707448 |
Swelling | 111.31 | 9.88 | 232 | 202309 | 188307 | 70537596 |
Sedation | 109.67 | 9.88 | 338 | 202203 | 46393 | 70679510 |
Cardiac arrest | 108.50 | 9.88 | 805 | 201736 | 159029 | 70566874 |
Confusional state | 107.81 | 9.88 | 1264 | 201277 | 283134 | 70442769 |
Extrapyramidal disorder | 107.51 | 9.88 | 204 | 202337 | 20546 | 70705357 |
Hyperreflexia | 107.28 | 9.88 | 119 | 202422 | 7323 | 70718580 |
Bipolar disorder | 106.83 | 9.88 | 120 | 202421 | 7488 | 70718415 |
Thrombocytopenia | 106.72 | 9.88 | 339 | 202202 | 238771 | 70487132 |
Gestational diabetes | 106.14 | 9.88 | 107 | 202434 | 5894 | 70720009 |
Alopecia | 105.98 | 9.88 | 258 | 202283 | 198232 | 70527671 |
Malignant neoplasm progression | 105.55 | 9.88 | 115 | 202426 | 121624 | 70604279 |
Tearfulness | 102.82 | 9.88 | 97 | 202444 | 4923 | 70720980 |
Intentional product misuse | 102.56 | 9.88 | 475 | 202066 | 79120 | 70646783 |
Electrocardiogram QRS complex prolonged | 102.25 | 9.88 | 133 | 202408 | 9673 | 70716230 |
Renal impairment | 100.22 | 9.88 | 160 | 202381 | 143777 | 70582126 |
Treatment failure | 99.64 | 9.88 | 161 | 202380 | 143981 | 70581922 |
Myoclonus | 98.93 | 9.88 | 227 | 202314 | 26128 | 70699775 |
Migraine | 98.22 | 9.88 | 438 | 202103 | 71800 | 70654103 |
Delusion | 97.55 | 9.88 | 187 | 202354 | 18978 | 70706925 |
Wound | 97.54 | 9.88 | 83 | 202458 | 98649 | 70627254 |
Disorientation | 96.65 | 9.88 | 374 | 202167 | 57549 | 70668354 |
Acute kidney injury | 92.82 | 9.88 | 887 | 201654 | 473737 | 70252166 |
Product substitution issue | 91.00 | 9.88 | 178 | 202363 | 18335 | 70707568 |
Mood swings | 90.11 | 9.88 | 176 | 202365 | 18110 | 70707793 |
C-reactive protein abnormal | 89.73 | 9.88 | 5 | 202536 | 38574 | 70687329 |
Hallucination, visual | 88.15 | 9.88 | 232 | 202309 | 29105 | 70696798 |
Arthralgia | 88.06 | 9.88 | 966 | 201575 | 502424 | 70223479 |
Dyspnoea | 84.79 | 9.88 | 1620 | 200921 | 768440 | 69957463 |
Plasma cell myeloma | 84.75 | 9.88 | 52 | 202489 | 73149 | 70652754 |
Tardive dyskinesia | 84.41 | 9.88 | 122 | 202419 | 9807 | 70716096 |
Haemoglobin decreased | 82.61 | 9.88 | 304 | 202237 | 204855 | 70521048 |
Pancytopenia | 81.75 | 9.88 | 195 | 202346 | 150912 | 70574991 |
Hallucination, auditory | 81.47 | 9.88 | 169 | 202372 | 18159 | 70707744 |
Nervousness | 80.51 | 9.88 | 233 | 202308 | 30887 | 70695016 |
Neuroleptic malignant syndrome | 79.50 | 9.88 | 207 | 202334 | 25800 | 70700103 |
Somnambulism | 79.10 | 9.88 | 86 | 202455 | 5174 | 70720729 |
Therapeutic product effect decreased | 78.62 | 9.88 | 183 | 202358 | 142835 | 70583068 |
Restless legs syndrome | 78.52 | 9.88 | 167 | 202374 | 18261 | 70707642 |
Muscle injury | 78.42 | 9.88 | 9 | 202532 | 38485 | 70687418 |
Diarrhoea | 77.56 | 9.88 | 1677 | 200864 | 781664 | 69944239 |
Dyskinesia | 77.54 | 9.88 | 276 | 202265 | 40798 | 70685105 |
Peripheral swelling | 77.12 | 9.88 | 380 | 202161 | 236183 | 70489720 |
Antidepressant drug level above therapeutic | 76.85 | 9.88 | 37 | 202504 | 590 | 70725313 |
Loss of consciousness | 76.25 | 9.88 | 729 | 201812 | 154987 | 70570916 |
Parkinsonism | 76.12 | 9.88 | 148 | 202393 | 15177 | 70710726 |
Decorticate posture | 75.93 | 9.88 | 30 | 202511 | 287 | 70725616 |
Sleep-related eating disorder | 75.45 | 9.88 | 38 | 202503 | 671 | 70725232 |
Thinking abnormal | 74.58 | 9.88 | 128 | 202413 | 11923 | 70713980 |
Myocardial depression | 74.19 | 9.88 | 34 | 202507 | 482 | 70725421 |
Abnormal behaviour | 74.09 | 9.88 | 243 | 202298 | 34466 | 70691437 |
Paraesthesia | 74.08 | 9.88 | 687 | 201854 | 144850 | 70581053 |
Self-injurious ideation | 73.19 | 9.88 | 67 | 202474 | 3271 | 70722632 |
Septic shock | 72.42 | 9.88 | 131 | 202410 | 112127 | 70613776 |
Antidepressant drug level increased | 72.25 | 9.88 | 31 | 202510 | 372 | 70725531 |
Sinus tachycardia | 72.00 | 9.88 | 237 | 202304 | 33676 | 70692227 |
Bone marrow failure | 71.92 | 9.88 | 25 | 202516 | 48985 | 70676918 |
Postmortem blood drug level increased | 71.89 | 9.88 | 38 | 202503 | 745 | 70725158 |
Mental disorder | 70.72 | 9.88 | 209 | 202332 | 28031 | 70697872 |
Memory impairment | 70.63 | 9.88 | 480 | 202061 | 92161 | 70633742 |
Gastrointestinal haemorrhage | 69.91 | 9.88 | 183 | 202358 | 137225 | 70588678 |
Psychotic symptom | 69.82 | 9.88 | 57 | 202484 | 2381 | 70723522 |
Impaired healing | 69.30 | 9.88 | 66 | 202475 | 74308 | 70651595 |
Folliculitis | 69.21 | 9.88 | 18 | 202523 | 42552 | 70683351 |
Blister | 68.78 | 9.88 | 113 | 202428 | 100413 | 70625490 |
Psychotic disorder | 68.33 | 9.88 | 250 | 202291 | 37451 | 70688452 |
Pleural effusion | 68.32 | 9.88 | 176 | 202365 | 132688 | 70593215 |
Homicidal ideation | 67.66 | 9.88 | 64 | 202477 | 3259 | 70722644 |
Hypomania | 67.47 | 9.88 | 85 | 202456 | 5987 | 70719916 |
Lung diffusion test abnormal | 66.81 | 9.88 | 26 | 202515 | 238 | 70725665 |
Atrial fibrillation | 66.68 | 9.88 | 285 | 202256 | 184063 | 70541840 |
Mental impairment | 66.29 | 9.88 | 150 | 202391 | 17105 | 70708798 |
Abnormal dreams | 66.11 | 9.88 | 113 | 202428 | 10490 | 70715413 |
Discomfort | 65.40 | 9.88 | 126 | 202415 | 105310 | 70620593 |
Galactorrhoea | 64.88 | 9.88 | 63 | 202478 | 3315 | 70722588 |
Cytomegalovirus infection | 64.27 | 9.88 | 17 | 202524 | 39741 | 70686162 |
Hepatic enzyme increased | 64.25 | 9.88 | 231 | 202310 | 156759 | 70569144 |
Apathy | 64.09 | 9.88 | 119 | 202422 | 11789 | 70714114 |
Camptocormia | 63.89 | 9.88 | 30 | 202511 | 451 | 70725452 |
Blood creatinine increased | 63.57 | 9.88 | 203 | 202338 | 142798 | 70583105 |
Physical assault | 63.43 | 9.88 | 45 | 202496 | 1519 | 70724384 |
Urinary incontinence | 62.84 | 9.88 | 244 | 202297 | 37598 | 70688305 |
Amnesia | 62.62 | 9.88 | 305 | 202236 | 51850 | 70674053 |
Sleep disorder due to general medical condition, insomnia type | 62.27 | 9.88 | 13 | 202528 | 35719 | 70690184 |
Neuropathy peripheral | 60.07 | 9.88 | 175 | 202366 | 126721 | 70599182 |
Meconium in amniotic fluid | 59.14 | 9.88 | 18 | 202523 | 70 | 70725833 |
Respiratory failure | 59.12 | 9.88 | 264 | 202277 | 168471 | 70557432 |
Pneumocystis jirovecii pneumonia | 58.93 | 9.88 | 8 | 202533 | 30074 | 70695829 |
Suicidal behaviour | 58.70 | 9.88 | 57 | 202484 | 2999 | 70722904 |
Mood altered | 58.65 | 9.88 | 139 | 202402 | 16336 | 70709567 |
Psychomotor retardation | 58.48 | 9.88 | 76 | 202465 | 5522 | 70720381 |
Abdominal discomfort | 58.38 | 9.88 | 366 | 202175 | 214292 | 70511611 |
Coma scale abnormal | 58.03 | 9.88 | 92 | 202449 | 8024 | 70717879 |
Impulsive behaviour | 57.91 | 9.88 | 54 | 202487 | 2700 | 70723203 |
Logorrhoea | 56.25 | 9.88 | 64 | 202477 | 4050 | 70721853 |
Clonus | 56.20 | 9.88 | 79 | 202462 | 6189 | 70719714 |
Euphoric mood | 56.17 | 9.88 | 83 | 202458 | 6806 | 70719097 |
Sinusitis | 55.57 | 9.88 | 271 | 202270 | 168924 | 70556979 |
Nasopharyngitis | 55.34 | 9.88 | 389 | 202152 | 221817 | 70504086 |
Libido decreased | 54.92 | 9.88 | 69 | 202472 | 4847 | 70721056 |
Muscle twitching | 54.75 | 9.88 | 152 | 202389 | 19675 | 70706228 |
Myelosuppression | 54.57 | 9.88 | 10 | 202531 | 30135 | 70695768 |
C-reactive protein increased | 54.09 | 9.88 | 150 | 202391 | 110367 | 70615536 |
Hypertonia | 54.01 | 9.88 | 79 | 202462 | 6419 | 70719484 |
Mobility decreased | 53.28 | 9.88 | 136 | 202405 | 102863 | 70623040 |
Hallucination | 52.79 | 9.88 | 386 | 202155 | 75874 | 70650029 |
Bruxism | 52.67 | 9.88 | 59 | 202482 | 3670 | 70722233 |
Dizziness | 52.48 | 9.88 | 1714 | 200827 | 462427 | 70263476 |
Dissociation | 52.17 | 9.88 | 56 | 202485 | 3320 | 70722583 |
Cytokine release syndrome | 51.94 | 9.88 | 7 | 202534 | 26460 | 70699443 |
Erythema | 51.85 | 9.88 | 345 | 202196 | 199218 | 70526685 |
Maternal exposure during pregnancy | 51.78 | 9.88 | 163 | 202378 | 115182 | 70610721 |
Vertigo | 51.63 | 9.88 | 331 | 202210 | 62312 | 70663591 |
Lymphocytic oesophagitis | 51.54 | 9.88 | 13 | 202528 | 19 | 70725884 |
Feelings of worthlessness | 50.83 | 9.88 | 26 | 202515 | 475 | 70725428 |
Oedema | 50.38 | 9.88 | 141 | 202400 | 103440 | 70622463 |
Irritable bowel syndrome | 49.90 | 9.88 | 43 | 202498 | 50807 | 70675096 |
Hepatic function abnormal | 49.79 | 9.88 | 73 | 202468 | 67923 | 70657980 |
Benzodiazepine drug level increased | 49.41 | 9.88 | 20 | 202521 | 205 | 70725698 |
Ascites | 48.99 | 9.88 | 73 | 202468 | 67474 | 70658429 |
Psoriatic arthropathy | 48.95 | 9.88 | 68 | 202473 | 64703 | 70661200 |
Dysphoria | 48.45 | 9.88 | 62 | 202479 | 4436 | 70721467 |
Pain | 48.34 | 9.88 | 1397 | 201144 | 627419 | 70098484 |
Erectile dysfunction | 47.82 | 9.88 | 114 | 202427 | 13448 | 70712455 |
Emotional disorder | 47.53 | 9.88 | 112 | 202429 | 13114 | 70712789 |
Depressive symptom | 47.50 | 9.88 | 66 | 202475 | 5115 | 70720788 |
Product use issue | 47.28 | 9.88 | 310 | 202231 | 179627 | 70546276 |
Inappropriate affect | 47.26 | 9.88 | 36 | 202505 | 1358 | 70724545 |
Accommodation disorder | 46.85 | 9.88 | 25 | 202516 | 500 | 70725403 |
Oedema peripheral | 46.74 | 9.88 | 421 | 202120 | 227670 | 70498233 |
Neovascularisation | 46.56 | 9.88 | 33 | 202508 | 1112 | 70724791 |
Foetal death | 46.38 | 9.88 | 72 | 202469 | 6167 | 70719736 |
Toxic epidermal necrolysis | 45.92 | 9.88 | 28 | 202513 | 39529 | 70686374 |
Pyramidal tract syndrome | 45.76 | 9.88 | 25 | 202516 | 525 | 70725378 |
Cardiac failure | 45.36 | 9.88 | 233 | 202308 | 143308 | 70582595 |
Persecutory delusion | 45.14 | 9.88 | 60 | 202481 | 4457 | 70721446 |
Weight increased | 44.48 | 9.88 | 954 | 201587 | 241377 | 70484526 |
White blood cell count decreased | 44.26 | 9.88 | 294 | 202247 | 169847 | 70556056 |
Interstitial lung disease | 44.18 | 9.88 | 152 | 202389 | 104533 | 70621370 |
Hot flush | 43.99 | 9.88 | 267 | 202274 | 49317 | 70676586 |
Lower respiratory tract infection | 43.60 | 9.88 | 168 | 202373 | 111745 | 70614158 |
Anticholinergic syndrome | 43.55 | 9.88 | 48 | 202493 | 2932 | 70722971 |
Paranoia | 43.33 | 9.88 | 128 | 202413 | 17160 | 70708743 |
Loss of libido | 43.21 | 9.88 | 44 | 202497 | 2453 | 70723450 |
Delirium | 43.00 | 9.88 | 362 | 202179 | 74252 | 70651651 |
Anaphylactic reaction | 42.76 | 9.88 | 94 | 202447 | 74880 | 70651023 |
General physical health deterioration | 42.74 | 9.88 | 449 | 202092 | 235582 | 70490321 |
Social anxiety disorder | 42.57 | 9.88 | 23 | 202518 | 472 | 70725431 |
Feeling jittery | 41.76 | 9.88 | 98 | 202443 | 11445 | 70714458 |
Hyperkalaemia | 41.53 | 9.88 | 160 | 202381 | 106431 | 70619472 |
Pleurothotonus | 41.50 | 9.88 | 42 | 202499 | 2324 | 70723579 |
Drug screen positive | 41.48 | 9.88 | 66 | 202475 | 5774 | 70720129 |
Obsessive-compulsive disorder | 41.36 | 9.88 | 63 | 202478 | 5307 | 70720596 |
Hostility | 41.34 | 9.88 | 41 | 202500 | 2214 | 70723689 |
Mucosal inflammation | 41.27 | 9.88 | 82 | 202459 | 67768 | 70658135 |
Gastrointestinal disorder | 41.24 | 9.88 | 158 | 202383 | 105269 | 70620634 |
Anorgasmia | 41.21 | 9.88 | 30 | 202511 | 1055 | 70724848 |
Personality disorder | 41.20 | 9.88 | 64 | 202477 | 5484 | 70720419 |
Miosis | 40.82 | 9.88 | 110 | 202431 | 13991 | 70711912 |
Abulia | 40.48 | 9.88 | 28 | 202513 | 907 | 70724996 |
Cerebral infarction | 40.26 | 9.88 | 38 | 202503 | 42971 | 70682932 |
Inappropriate antidiuretic hormone secretion | 40.22 | 9.88 | 152 | 202389 | 23124 | 70702779 |
Red blood cell sedimentation rate increased | 40.00 | 9.88 | 31 | 202510 | 38611 | 70687292 |
Panic disorder | 39.91 | 9.88 | 45 | 202496 | 2819 | 70723084 |
Cardiogenic shock | 39.83 | 9.88 | 207 | 202334 | 36100 | 70689803 |
Malignant mediastinal neoplasm | 39.76 | 9.88 | 27 | 202514 | 848 | 70725055 |
Epilepsy | 39.74 | 9.88 | 217 | 202324 | 38567 | 70687336 |
Sleep disorder | 39.74 | 9.88 | 338 | 202203 | 69534 | 70656369 |
Cough | 39.57 | 9.88 | 672 | 201869 | 324705 | 70401198 |
Respiratory depression | 39.52 | 9.88 | 158 | 202383 | 24673 | 70701230 |
Persistent genital arousal disorder | 39.52 | 9.88 | 19 | 202522 | 302 | 70725601 |
Prostate cancer | 39.14 | 9.88 | 20 | 202521 | 31143 | 70694760 |
Fluid retention | 39.08 | 9.88 | 76 | 202465 | 63309 | 70662594 |
Hereditary non-polyposis colorectal cancer syndrome | 38.89 | 9.88 | 8 | 202533 | 0 | 70725903 |
Antipsychotic drug level above therapeutic | 38.18 | 9.88 | 37 | 202504 | 1942 | 70723961 |
Libido increased | 38.06 | 9.88 | 36 | 202505 | 1833 | 70724070 |
Cardiac failure congestive | 37.83 | 9.88 | 229 | 202312 | 135228 | 70590675 |
Fall | 37.80 | 9.88 | 1589 | 200952 | 442507 | 70283396 |
Persistent depressive disorder | 37.77 | 9.88 | 28 | 202513 | 1013 | 70724890 |
Blood bilirubin increased | 37.65 | 9.88 | 71 | 202470 | 59830 | 70666073 |
Feeling of despair | 37.54 | 9.88 | 42 | 202499 | 2609 | 70723294 |
Tinnitus | 37.46 | 9.88 | 203 | 202338 | 35973 | 70689930 |
Reversible cerebral vasoconstriction syndrome | 37.10 | 9.88 | 42 | 202499 | 2643 | 70723260 |
Drug intolerance | 37.03 | 9.88 | 439 | 202102 | 225248 | 70500655 |
Ill-defined disorder | 37.00 | 9.88 | 62 | 202479 | 54679 | 70671224 |
Amniorrhexis | 36.74 | 9.88 | 10 | 202531 | 23 | 70725880 |
Hip arthroplasty | 36.74 | 9.88 | 17 | 202524 | 28023 | 70697880 |
Metabolic syndrome | 36.41 | 9.88 | 40 | 202501 | 2435 | 70723468 |
Social avoidant behaviour | 36.40 | 9.88 | 55 | 202486 | 4601 | 70721302 |
Sexual dysfunction | 36.25 | 9.88 | 67 | 202474 | 6614 | 70719289 |
Opsoclonus myoclonus | 35.95 | 9.88 | 16 | 202525 | 211 | 70725692 |
Self esteem decreased | 35.90 | 9.88 | 26 | 202515 | 907 | 70724996 |
Bronchopulmonary aspergillosis | 35.86 | 9.88 | 8 | 202533 | 20994 | 70704909 |
Cardiotoxicity | 35.79 | 9.88 | 90 | 202451 | 10980 | 70714923 |
Acute myeloid leukaemia | 35.78 | 9.88 | 22 | 202519 | 30918 | 70694985 |
Hyponatraemia | 35.67 | 9.88 | 649 | 201892 | 159438 | 70566465 |
Congestive cardiomyopathy | 35.50 | 9.88 | 89 | 202452 | 10837 | 70715066 |
Endometriosis | 35.48 | 9.88 | 45 | 202496 | 3191 | 70722712 |
Hypersomnia | 35.38 | 9.88 | 135 | 202406 | 20629 | 70705274 |
Suspected suicide | 35.28 | 9.88 | 78 | 202463 | 8756 | 70717147 |
Death | 35.26 | 9.88 | 1149 | 201392 | 508912 | 70216991 |
Bezoar | 35.19 | 9.88 | 38 | 202503 | 2268 | 70723635 |
Tumour lysis syndrome | 34.78 | 9.88 | 9 | 202532 | 21351 | 70704552 |
Adjustment disorder with mixed anxiety and depressed mood | 34.78 | 9.88 | 12 | 202529 | 75 | 70725828 |
Drug eruption | 34.56 | 9.88 | 37 | 202504 | 39459 | 70686444 |
International normalised ratio increased | 34.21 | 9.88 | 117 | 202424 | 80609 | 70645294 |
Nephropathy toxic | 33.82 | 9.88 | 6 | 202535 | 18508 | 70707395 |
Toxicologic test abnormal | 33.81 | 9.88 | 29 | 202512 | 1298 | 70724605 |
Somatic symptom disorder | 33.73 | 9.88 | 35 | 202506 | 1995 | 70723908 |
Urinary retention | 33.61 | 9.88 | 261 | 202280 | 52259 | 70673644 |
Hypothermia | 33.55 | 9.88 | 132 | 202409 | 20462 | 70705441 |
Drug screen false positive | 33.54 | 9.88 | 26 | 202515 | 1007 | 70724896 |
Neutrophil count decreased | 33.47 | 9.88 | 124 | 202417 | 83432 | 70642471 |
Nystagmus | 33.38 | 9.88 | 79 | 202462 | 9276 | 70716627 |
Negative thoughts | 33.38 | 9.88 | 29 | 202512 | 1321 | 70724582 |
Total lung capacity increased | 33.35 | 9.88 | 25 | 202516 | 920 | 70724983 |
Middle insomnia | 33.29 | 9.88 | 102 | 202439 | 13951 | 70711952 |
Leukopenia | 33.08 | 9.88 | 174 | 202367 | 106386 | 70619517 |
Tachyphrenia | 33.07 | 9.88 | 34 | 202507 | 1917 | 70723986 |
Haematuria | 32.83 | 9.88 | 84 | 202457 | 63489 | 70662414 |
Victim of sexual abuse | 32.58 | 9.88 | 19 | 202522 | 454 | 70725449 |
Cognitive disorder | 32.13 | 9.88 | 290 | 202251 | 60666 | 70665237 |
Rheumatoid nodule | 32.04 | 9.88 | 3 | 202538 | 15064 | 70710839 |
Myelodysplastic syndrome | 31.98 | 9.88 | 23 | 202518 | 29762 | 70696141 |
Pruritus | 31.97 | 9.88 | 747 | 201794 | 344813 | 70381090 |
Postmortem blood drug level abnormal | 31.83 | 9.88 | 21 | 202520 | 628 | 70725275 |
Pneumonitis | 31.50 | 9.88 | 68 | 202473 | 54529 | 70671374 |
Tubulointerstitial nephritis | 31.22 | 9.88 | 29 | 202512 | 33047 | 70692856 |
Bipolar II disorder | 30.95 | 9.88 | 17 | 202524 | 361 | 70725542 |
Colitis | 30.93 | 9.88 | 87 | 202454 | 63727 | 70662176 |
Transplant rejection | 30.87 | 9.88 | 7 | 202534 | 18164 | 70707739 |
Acute myocardial infarction | 30.64 | 9.88 | 106 | 202435 | 72781 | 70653122 |
Intentional product use issue | 30.54 | 9.88 | 209 | 202332 | 119933 | 70605970 |
Rhabdomyolysis | 30.38 | 9.88 | 412 | 202129 | 95348 | 70630555 |
Head discomfort | 30.36 | 9.88 | 94 | 202447 | 12929 | 70712974 |
Bradyphrenia | 30.23 | 9.88 | 79 | 202462 | 9867 | 70716036 |
Derealisation | 30.16 | 9.88 | 29 | 202512 | 1507 | 70724396 |
Skin candida | 30.06 | 9.88 | 31 | 202510 | 1754 | 70724149 |
HELLP syndrome | 30.01 | 9.88 | 21 | 202520 | 693 | 70725210 |
Speech disorder | 29.99 | 9.88 | 247 | 202294 | 50333 | 70675570 |
Panic reaction | 29.96 | 9.88 | 48 | 202493 | 4223 | 70721680 |
Alcoholism | 29.88 | 9.88 | 49 | 202492 | 4396 | 70721507 |
Bacteraemia | 29.72 | 9.88 | 24 | 202517 | 29285 | 70696618 |
Parkinsonism hyperpyrexia syndrome | 29.43 | 9.88 | 14 | 202527 | 217 | 70725686 |
Tension | 29.30 | 9.88 | 46 | 202495 | 3978 | 70721925 |
Endolymphatic hydrops | 29.17 | 9.88 | 6 | 202535 | 0 | 70725903 |
Tenosynovitis | 29.15 | 9.88 | 3 | 202538 | 13973 | 70711930 |
Cytopenia | 28.78 | 9.88 | 7 | 202534 | 17316 | 70708587 |
Rapid eye movement sleep behaviour disorder | 28.74 | 9.88 | 16 | 202525 | 349 | 70725554 |
Substance abuse | 28.74 | 9.88 | 77 | 202464 | 9760 | 70716143 |
Kleptomania | 28.65 | 9.88 | 8 | 202533 | 21 | 70725882 |
Dependence | 28.47 | 9.88 | 34 | 202507 | 2266 | 70723637 |
Haematotoxicity | 28.35 | 9.88 | 3 | 202538 | 13671 | 70712232 |
Hypocalcaemia | 28.34 | 9.88 | 53 | 202488 | 44806 | 70681097 |
Depression suicidal | 28.31 | 9.88 | 38 | 202503 | 2849 | 70723054 |
Renal failure | 28.30 | 9.88 | 375 | 202166 | 188695 | 70537208 |
Ejaculation disorder | 28.27 | 9.88 | 18 | 202523 | 506 | 70725397 |
Skin necrosis | 28.24 | 9.88 | 6 | 202535 | 16285 | 70709618 |
Osteonecrosis of jaw | 28.12 | 9.88 | 46 | 202495 | 40956 | 70684947 |
Unemployment | 28.09 | 9.88 | 9 | 202532 | 43 | 70725860 |
Product residue present | 28.05 | 9.88 | 41 | 202500 | 3329 | 70722574 |
Enuresis | 28.01 | 9.88 | 38 | 202503 | 2879 | 70723024 |
Palmar-plantar erythrodysaesthesia syndrome | 27.99 | 9.88 | 27 | 202514 | 30220 | 70695683 |
Multiple organ dysfunction syndrome | 27.96 | 9.88 | 188 | 202353 | 108327 | 70617576 |
Macrophages increased | 27.89 | 9.88 | 13 | 202528 | 192 | 70725711 |
Liver disorder | 27.63 | 9.88 | 87 | 202454 | 61481 | 70664422 |
Diverticulitis | 27.54 | 9.88 | 48 | 202493 | 41686 | 70684217 |
Full blood count abnormal | 27.29 | 9.88 | 178 | 202363 | 33700 | 70692203 |
Affect lability | 27.24 | 9.88 | 77 | 202464 | 10069 | 70715834 |
Drug use disorder | 27.12 | 9.88 | 67 | 202474 | 8084 | 70717819 |
Epstein-Barr virus infection | 27.10 | 9.88 | 3 | 202538 | 13195 | 70712708 |
Iodine allergy | 27.06 | 9.88 | 18 | 202523 | 546 | 70725357 |
Alcohol interaction | 26.94 | 9.88 | 48 | 202493 | 4605 | 70721298 |
Right ventricular failure | 26.94 | 9.88 | 15 | 202526 | 22259 | 70703644 |
COVID-19 | 26.86 | 9.88 | 184 | 202357 | 105573 | 70620330 |
Nervous system disorder | 26.72 | 9.88 | 138 | 202403 | 24008 | 70701895 |
Upper respiratory tract infection | 26.57 | 9.88 | 126 | 202415 | 79148 | 70646755 |
Tonic convulsion | 26.38 | 9.88 | 31 | 202510 | 2031 | 70723872 |
Antipsychotic drug level increased | 26.36 | 9.88 | 52 | 202489 | 5388 | 70720515 |
Pulmonary arterial hypertension | 26.35 | 9.88 | 33 | 202508 | 32822 | 70693081 |
Hepatocellular injury | 26.22 | 9.88 | 223 | 202318 | 45868 | 70680035 |
Cogwheel rigidity | 26.01 | 9.88 | 37 | 202504 | 2931 | 70722972 |
Decreased interest | 25.98 | 9.88 | 40 | 202501 | 3401 | 70722502 |
Dysarthria | 25.82 | 9.88 | 282 | 202259 | 62031 | 70663872 |
Psychiatric symptom | 25.79 | 9.88 | 58 | 202483 | 6586 | 70719317 |
Thermophobia | 25.72 | 9.88 | 9 | 202532 | 59 | 70725844 |
Drug ineffective for unapproved indication | 25.49 | 9.88 | 193 | 202348 | 38345 | 70687558 |
Affective disorder | 25.44 | 9.88 | 62 | 202479 | 7417 | 70718486 |
Pain in extremity | 25.34 | 9.88 | 728 | 201813 | 327354 | 70398549 |
Feeling drunk | 25.22 | 9.88 | 45 | 202496 | 4322 | 70721581 |
Musculoskeletal stiffness | 25.16 | 9.88 | 285 | 202256 | 147475 | 70578428 |
Pressure of speech | 25.12 | 9.88 | 22 | 202519 | 1013 | 70724890 |
Diffuse large B-cell lymphoma | 24.98 | 9.88 | 4 | 202537 | 13298 | 70712605 |
Headache | 24.97 | 9.88 | 1952 | 200589 | 578453 | 70147450 |
Pathogen resistance | 24.93 | 9.88 | 4 | 202537 | 13275 | 70712628 |
Respiratory tract inflammation | 24.92 | 9.88 | 20 | 202521 | 815 | 70725088 |
Colitis microscopic | 24.83 | 9.88 | 69 | 202472 | 8936 | 70716967 |
Vision blurred | 24.75 | 9.88 | 395 | 202146 | 94589 | 70631314 |
Reduced facial expression | 24.68 | 9.88 | 32 | 202509 | 2320 | 70723583 |
Thrombosis | 24.61 | 9.88 | 121 | 202420 | 75284 | 70650619 |
Schizophreniform disorder | 24.52 | 9.88 | 11 | 202530 | 148 | 70725755 |
Brain death | 24.50 | 9.88 | 49 | 202492 | 5129 | 70720774 |
Hospitalisation | 24.42 | 9.88 | 137 | 202404 | 82431 | 70643472 |
Yawning | 24.40 | 9.88 | 24 | 202517 | 1283 | 70724620 |
Phagophobia | 24.35 | 9.88 | 8 | 202533 | 42 | 70725861 |
ECG P wave inverted | 24.31 | 9.88 | 5 | 202536 | 0 | 70725903 |
Electrocardiogram QRS complex shortened | 24.19 | 9.88 | 18 | 202523 | 655 | 70725248 |
Lung disorder | 24.14 | 9.88 | 109 | 202432 | 69375 | 70656528 |
Substance abuser | 24.13 | 9.88 | 11 | 202530 | 154 | 70725749 |
Frustration tolerance decreased | 24.00 | 9.88 | 57 | 202484 | 6708 | 70719195 |
Tongue biting | 23.99 | 9.88 | 28 | 202513 | 1821 | 70724082 |
Heart rate increased | 23.87 | 9.88 | 431 | 202110 | 105717 | 70620186 |
Herpes zoster | 23.84 | 9.88 | 144 | 202397 | 85091 | 70640812 |
Electric shock sensation | 23.75 | 9.88 | 17 | 202524 | 582 | 70725321 |
Aplastic anaemia | 23.72 | 9.88 | 9 | 202532 | 16707 | 70709196 |
Hyperprolactinaemia | 23.62 | 9.88 | 44 | 202497 | 4369 | 70721534 |
Therapeutic response unexpected | 23.61 | 9.88 | 109 | 202432 | 18122 | 70707781 |
Abnormal weight gain | 23.61 | 9.88 | 31 | 202510 | 2275 | 70723628 |
Eye movement disorder | 23.54 | 9.88 | 60 | 202481 | 7380 | 70718523 |
Stress | 23.47 | 9.88 | 297 | 202244 | 67669 | 70658234 |
Hyperthermia | 23.34 | 9.88 | 102 | 202439 | 16569 | 70709334 |
Antidepressant discontinuation syndrome | 23.31 | 9.88 | 6 | 202535 | 10 | 70725893 |
Neurodegenerative disorder | 23.24 | 9.88 | 15 | 202526 | 432 | 70725471 |
Renal papillary necrosis | 23.23 | 9.88 | 14 | 202527 | 356 | 70725547 |
Neoplasm progression | 23.17 | 9.88 | 60 | 202481 | 45168 | 70680735 |
Kidney duplex | 22.95 | 9.88 | 6 | 202535 | 11 | 70725892 |
Merycism | 22.95 | 9.88 | 12 | 202529 | 230 | 70725673 |
Coma acidotic | 22.94 | 9.88 | 10 | 202531 | 125 | 70725778 |
Vasoplegia syndrome | 22.87 | 9.88 | 36 | 202505 | 3120 | 70722783 |
Blood urea increased | 22.68 | 9.88 | 62 | 202479 | 45847 | 70680056 |
Haemophagocytic lymphohistiocytosis | 22.60 | 9.88 | 14 | 202527 | 19598 | 70706305 |
Drug abuser | 22.55 | 9.88 | 51 | 202490 | 5813 | 70720090 |
Balance disorder | 22.44 | 9.88 | 372 | 202169 | 89756 | 70636147 |
Peritonitis | 22.34 | 9.88 | 25 | 202516 | 26134 | 70699769 |
Transfusion | 22.33 | 9.88 | 13 | 202528 | 18823 | 70707080 |
Poor quality sleep | 22.31 | 9.88 | 116 | 202425 | 20233 | 70705670 |
Loose associations | 22.29 | 9.88 | 8 | 202533 | 57 | 70725846 |
External auditory canal atresia | 22.29 | 9.88 | 6 | 202535 | 13 | 70725890 |
Haemolytic anaemia | 22.28 | 9.88 | 10 | 202531 | 16784 | 70709119 |
Haemoptysis | 22.19 | 9.88 | 74 | 202467 | 51378 | 70674525 |
Cardiomyopathy | 22.13 | 9.88 | 140 | 202401 | 26233 | 70699670 |
Narcolepsy | 22.11 | 9.88 | 22 | 202519 | 1193 | 70724710 |
Sleep terror | 22.11 | 9.88 | 22 | 202519 | 1193 | 70724710 |
Joint range of motion decreased | 22.09 | 9.88 | 25 | 202516 | 26001 | 70699902 |
Iris coloboma | 21.98 | 9.88 | 6 | 202535 | 14 | 70725889 |
Retinal coloboma | 21.98 | 9.88 | 6 | 202535 | 14 | 70725889 |
Neurotoxicity | 21.85 | 9.88 | 32 | 202509 | 29794 | 70696109 |
Erythema dyschromicum perstans | 21.83 | 9.88 | 8 | 202533 | 61 | 70725842 |
Asphyxia | 21.70 | 9.88 | 72 | 202469 | 10270 | 70715633 |
Thrombotic microangiopathy | 21.62 | 9.88 | 12 | 202529 | 17836 | 70708067 |
Cold sweat | 21.50 | 9.88 | 101 | 202440 | 16915 | 70708988 |
Graft versus host disease | 21.47 | 9.88 | 8 | 202533 | 15015 | 70710888 |
Liver function test increased | 21.37 | 9.88 | 40 | 202501 | 33807 | 70692096 |
Cataract | 21.37 | 9.88 | 84 | 202457 | 55561 | 70670342 |
Hepatotoxicity | 21.29 | 9.88 | 60 | 202481 | 43926 | 70681977 |
Device related infection | 21.25 | 9.88 | 37 | 202504 | 32148 | 70693755 |
Sleep paralysis | 21.20 | 9.88 | 16 | 202525 | 595 | 70725308 |
Incoherent | 21.16 | 9.88 | 57 | 202484 | 7249 | 70718654 |
Otospondylomegaepiphyseal dysplasia | 21.11 | 9.88 | 7 | 202534 | 38 | 70725865 |
Obsessive thoughts | 21.07 | 9.88 | 20 | 202521 | 1023 | 70724880 |
Splenomegaly | 21.02 | 9.88 | 14 | 202527 | 18856 | 70707047 |
Testicular atrophy | 21.01 | 9.88 | 13 | 202528 | 347 | 70725556 |
Acquired amegakaryocytic thrombocytopenia | 20.90 | 9.88 | 6 | 202535 | 18 | 70725885 |
Blood lactate dehydrogenase increased | 20.89 | 9.88 | 43 | 202498 | 35084 | 70690819 |
Cytomegalovirus viraemia | 20.88 | 9.88 | 4 | 202537 | 11681 | 70714222 |
Hepatic failure | 20.87 | 9.88 | 89 | 202452 | 57536 | 70668367 |
Helplessness | 20.78 | 9.88 | 13 | 202528 | 354 | 70725549 |
Phaeochromocytoma malignant | 20.68 | 9.88 | 8 | 202533 | 72 | 70725831 |
Dialysis | 20.65 | 9.88 | 12 | 202529 | 17390 | 70708513 |
Osteoporosis | 20.64 | 9.88 | 71 | 202470 | 48836 | 70677067 |
Muscle mass | 20.61 | 9.88 | 14 | 202527 | 440 | 70725463 |
Paradoxical drug reaction | 20.46 | 9.88 | 53 | 202488 | 6583 | 70719320 |
Bradypnoea | 20.46 | 9.88 | 47 | 202494 | 5412 | 70720491 |
Pulmonary pain | 20.41 | 9.88 | 36 | 202505 | 3426 | 70722477 |
Skin maceration | 20.39 | 9.88 | 7 | 202534 | 43 | 70725860 |
Concussion | 20.38 | 9.88 | 62 | 202479 | 8447 | 70717456 |
Second primary malignancy | 20.31 | 9.88 | 6 | 202535 | 13045 | 70712858 |
Palpitations | 20.28 | 9.88 | 436 | 202105 | 110317 | 70615586 |
Flight of ideas | 20.24 | 9.88 | 17 | 202524 | 739 | 70725164 |
Trunk injury | 20.20 | 9.88 | 6 | 202535 | 21 | 70725882 |
Hypervigilance | 20.20 | 9.88 | 14 | 202527 | 455 | 70725448 |
Catatonia | 20.18 | 9.88 | 60 | 202481 | 8073 | 70717830 |
Emotional poverty | 20.16 | 9.88 | 17 | 202524 | 743 | 70725160 |
Foaming at mouth | 20.09 | 9.88 | 25 | 202516 | 1739 | 70724164 |
Cellulitis | 20.07 | 9.88 | 183 | 202358 | 98745 | 70627158 |
External ear disorder | 20.03 | 9.88 | 8 | 202533 | 79 | 70725824 |
Blood creatine phosphokinase increased | 20.01 | 9.88 | 265 | 202276 | 60998 | 70664905 |
Food aversion | 19.99 | 9.88 | 17 | 202524 | 752 | 70725151 |
Dry mouth | 19.89 | 9.88 | 297 | 202244 | 70160 | 70655743 |
COVID-19 pneumonia | 19.88 | 9.88 | 20 | 202521 | 21949 | 70703954 |
Burnout syndrome | 19.85 | 9.88 | 12 | 202529 | 307 | 70725596 |
Melaena | 19.82 | 9.88 | 88 | 202453 | 56267 | 70669636 |
Distributive shock | 19.77 | 9.88 | 28 | 202513 | 2209 | 70723694 |
Histamine level increased | 19.76 | 9.88 | 8 | 202533 | 82 | 70725821 |
Increased appetite | 19.76 | 9.88 | 71 | 202470 | 10542 | 70715361 |
Hypercalcaemia | 19.69 | 9.88 | 43 | 202498 | 34342 | 70691561 |
Hyperchloraemia | 19.67 | 9.88 | 19 | 202522 | 993 | 70724910 |
Respiratory tract infection | 19.67 | 9.88 | 59 | 202482 | 42339 | 70683564 |
False positive investigation result | 19.64 | 9.88 | 18 | 202523 | 880 | 70725023 |
Disturbance in sexual arousal | 19.63 | 9.88 | 10 | 202531 | 181 | 70725722 |
Starvation ketoacidosis | 19.61 | 9.88 | 9 | 202532 | 128 | 70725775 |
Perinatal depression | 19.61 | 9.88 | 12 | 202529 | 314 | 70725589 |
Clostridium difficile infection | 19.49 | 9.88 | 52 | 202489 | 38764 | 70687139 |
Basal cell carcinoma | 19.42 | 9.88 | 42 | 202499 | 33656 | 70692247 |
Urticaria | 19.39 | 9.88 | 338 | 202203 | 162711 | 70563192 |
Drug resistance | 19.30 | 9.88 | 51 | 202490 | 38139 | 70687764 |
Pneumonia bacterial | 19.01 | 9.88 | 12 | 202529 | 16629 | 70709274 |
Soft tissue injury | 18.97 | 9.88 | 24 | 202517 | 1698 | 70724205 |
Enthesopathy | 18.84 | 9.88 | 4 | 202537 | 10865 | 70715038 |
Creatinine renal clearance decreased | 18.84 | 9.88 | 13 | 202528 | 17187 | 70708716 |
Micturition urgency | 18.82 | 9.88 | 73 | 202468 | 11241 | 70714662 |
Activation syndrome | 18.71 | 9.88 | 11 | 202530 | 267 | 70725636 |
Pre-existing condition improved | 18.68 | 9.88 | 43 | 202498 | 4959 | 70720944 |
Depressed level of consciousness | 18.61 | 9.88 | 352 | 202189 | 87079 | 70638824 |
Sciatic nerve neuropathy | 18.49 | 9.88 | 12 | 202529 | 349 | 70725554 |
Ocular hyperaemia | 18.48 | 9.88 | 26 | 202515 | 24613 | 70701290 |
Orthostatic intolerance | 18.48 | 9.88 | 24 | 202517 | 1743 | 70724160 |
Impaired driving ability | 18.41 | 9.88 | 42 | 202499 | 4815 | 70721088 |
Proteinuria | 18.29 | 9.88 | 35 | 202506 | 29339 | 70696564 |
Nodule | 18.27 | 9.88 | 18 | 202523 | 19951 | 70705952 |
Generalised oedema | 18.26 | 9.88 | 21 | 202520 | 21687 | 70704216 |
Gambling disorder | 18.23 | 9.88 | 25 | 202516 | 1913 | 70723990 |
Abnormal sleep-related event | 18.21 | 9.88 | 17 | 202524 | 851 | 70725052 |
Imprisonment | 18.18 | 9.88 | 14 | 202527 | 537 | 70725366 |
Muscle tightness | 18.05 | 9.88 | 74 | 202467 | 11688 | 70714215 |
Dystonia | 18.04 | 9.88 | 107 | 202434 | 19599 | 70706304 |
Gambling | 18.00 | 9.88 | 11 | 202530 | 287 | 70725616 |
Oropharyngeal pain | 17.91 | 9.88 | 182 | 202359 | 96128 | 70629775 |
Transient psychosis | 17.81 | 9.88 | 7 | 202534 | 66 | 70725837 |
Eosinophilic pustular folliculitis | 17.81 | 9.88 | 8 | 202533 | 108 | 70725795 |
Vitamin K decreased | 17.71 | 9.88 | 7 | 202534 | 67 | 70725836 |
Wrong dose | 17.70 | 9.88 | 21 | 202520 | 1390 | 70724513 |
Incontinence | 17.70 | 9.88 | 79 | 202462 | 12949 | 70712954 |
Anhedonia | 17.69 | 9.88 | 84 | 202457 | 14129 | 70711774 |
Micturition disorder | 17.65 | 9.88 | 35 | 202506 | 3640 | 70722263 |
Myocardial infarction | 17.58 | 9.88 | 365 | 202176 | 171280 | 70554623 |
Attention deficit hyperactivity disorder | 17.54 | 9.88 | 31 | 202510 | 2956 | 70722947 |
Adrenal insufficiency | 17.53 | 9.88 | 28 | 202513 | 25167 | 70700736 |
Hypokinesia | 17.50 | 9.88 | 97 | 202444 | 17335 | 70708568 |
Wheezing | 17.49 | 9.88 | 178 | 202363 | 93992 | 70631911 |
Drug level increased | 17.46 | 9.88 | 170 | 202371 | 36299 | 70689604 |
CYP3A4 polymorphism | 17.44 | 9.88 | 7 | 202534 | 70 | 70725833 |
Metastases to bone | 17.40 | 9.88 | 23 | 202518 | 22353 | 70703550 |
Normal pressure hydrocephalus | 17.38 | 9.88 | 13 | 202528 | 477 | 70725426 |
Antisocial behaviour | 17.35 | 9.88 | 14 | 202527 | 575 | 70725328 |
Bradykinesia | 17.35 | 9.88 | 54 | 202487 | 7448 | 70718455 |
Accidental death | 17.33 | 9.88 | 36 | 202505 | 3872 | 70722031 |
Slow response to stimuli | 17.29 | 9.88 | 23 | 202518 | 1710 | 70724193 |
Dyspnoea exertional | 17.28 | 9.88 | 142 | 202399 | 78288 | 70647615 |
Potentiating drug interaction | 17.28 | 9.88 | 57 | 202484 | 8107 | 70717796 |
Priapism | 17.22 | 9.88 | 37 | 202504 | 4073 | 70721830 |
Female sexual dysfunction | 17.19 | 9.88 | 6 | 202535 | 39 | 70725864 |
Oesophageal carcinoma | 17.18 | 9.88 | 3 | 202538 | 9363 | 70716540 |
Productive cough | 17.18 | 9.88 | 142 | 202399 | 78195 | 70647708 |
Hyperacusis | 17.17 | 9.88 | 25 | 202516 | 2023 | 70723880 |
Arachnoid cyst | 17.16 | 9.88 | 11 | 202530 | 313 | 70725590 |
Emotional distress | 17.15 | 9.88 | 172 | 202369 | 37016 | 70688887 |
Pulmonary mass | 17.12 | 9.88 | 30 | 202511 | 26003 | 70699900 |
Skin ulcer | 17.04 | 9.88 | 75 | 202466 | 48070 | 70677833 |
Cerebellar haematoma | 17 | 9.88 | 14 | 202527 | 592 | 70725311 |
Localised infection | 16.97 | 9.88 | 44 | 202497 | 33114 | 70692789 |
Ataxia | 16.92 | 9.88 | 119 | 202422 | 23098 | 70702805 |
Sleep apnoea syndrome | 16.91 | 9.88 | 155 | 202386 | 32558 | 70693345 |
Disseminated intravascular coagulation | 16.88 | 9.88 | 45 | 202496 | 33553 | 70692350 |
Sluggishness | 16.84 | 9.88 | 46 | 202495 | 5897 | 70720006 |
Dysphemia | 16.80 | 9.88 | 32 | 202509 | 3231 | 70722672 |
Left ventricular dysfunction | 16.76 | 9.88 | 98 | 202443 | 17859 | 70708044 |
Catecholamines urine increased | 16.73 | 9.88 | 5 | 202536 | 18 | 70725885 |
Pericardial effusion | 16.73 | 9.88 | 62 | 202479 | 41714 | 70684189 |
Purging | 16.69 | 9.88 | 6 | 202535 | 43 | 70725860 |
Arthritis | 16.67 | 9.88 | 189 | 202352 | 97791 | 70628112 |
Blood potassium increased | 16.64 | 9.88 | 33 | 202508 | 27293 | 70698610 |
Therapy non-responder | 16.61 | 9.88 | 140 | 202401 | 76775 | 70649128 |
Back pain | 16.57 | 9.88 | 620 | 201921 | 270532 | 70455371 |
Fear | 16.55 | 9.88 | 109 | 202432 | 20702 | 70705201 |
Injection site erythema | 16.54 | 9.88 | 131 | 202410 | 72793 | 70653110 |
Hallucination, tactile | 16.49 | 9.88 | 13 | 202528 | 516 | 70725387 |
Akinesia | 16.49 | 9.88 | 31 | 202510 | 3100 | 70722803 |
Aspartate aminotransferase increased | 16.48 | 9.88 | 259 | 202282 | 126719 | 70599184 |
Impaired work ability | 16.45 | 9.88 | 91 | 202450 | 16249 | 70709654 |
Haematocrit decreased | 16.40 | 9.88 | 96 | 202445 | 57162 | 70668741 |
Chest discomfort | 16.38 | 9.88 | 253 | 202288 | 124128 | 70601775 |
Implant site extravasation | 16.34 | 9.88 | 15 | 202526 | 735 | 70725168 |
Prescribed overdose | 16.25 | 9.88 | 133 | 202408 | 27048 | 70698855 |
Pulmonary contusion | 16.24 | 9.88 | 7 | 202534 | 85 | 70725818 |
Hypotonia | 16.16 | 9.88 | 72 | 202469 | 11793 | 70714110 |
Anticonvulsant drug level above therapeutic | 16.15 | 9.88 | 18 | 202523 | 1113 | 70724790 |
Cold agglutinins positive | 16.12 | 9.88 | 6 | 202535 | 48 | 70725855 |
Delusional disorder, unspecified type | 16.12 | 9.88 | 15 | 202526 | 748 | 70725155 |
Acute hepatitis B | 16.10 | 9.88 | 12 | 202529 | 438 | 70725465 |
Upper gastrointestinal haemorrhage | 16.09 | 9.88 | 54 | 202487 | 37423 | 70688480 |
Drug specific antibody | 16.02 | 9.88 | 26 | 202515 | 2313 | 70723590 |
Jaundice | 16.01 | 9.88 | 81 | 202460 | 50027 | 70675876 |
Blood ethanol increased | 16.00 | 9.88 | 14 | 202527 | 644 | 70725259 |
Exposure via ingestion | 15.93 | 9.88 | 40 | 202501 | 4875 | 70721028 |
Peak expiratory flow rate decreased | 15.90 | 9.88 | 14 | 202527 | 649 | 70725254 |
Toxic cardiomyopathy | 15.80 | 9.88 | 11 | 202530 | 360 | 70725543 |
Focal dyscognitive seizures | 15.77 | 9.88 | 32 | 202509 | 3385 | 70722518 |
Blood calcium decreased | 15.77 | 9.88 | 37 | 202504 | 28809 | 70697094 |
Male orgasmic disorder | 15.71 | 9.88 | 6 | 202535 | 52 | 70725851 |
Conversion disorder | 15.63 | 9.88 | 22 | 202519 | 1726 | 70724177 |
Alanine aminotransferase increased | 15.58 | 9.88 | 312 | 202229 | 147168 | 70578735 |
Renal disorder | 15.49 | 9.88 | 56 | 202485 | 37953 | 70687950 |
Cardiac failure chronic | 15.48 | 9.88 | 5 | 202536 | 10264 | 70715639 |
Drug level above therapeutic | 15.45 | 9.88 | 53 | 202488 | 7689 | 70718214 |
Aspergillus infection | 15.34 | 9.88 | 17 | 202524 | 17851 | 70708052 |
Hepatocellular carcinoma | 15.34 | 9.88 | 5 | 202536 | 10203 | 70715700 |
Cerebral vasoconstriction | 15.28 | 9.88 | 19 | 202522 | 1321 | 70724582 |
Cystitis haemorrhagic | 15.23 | 9.88 | 3 | 202538 | 8590 | 70717313 |
Injection site pain | 15.23 | 9.88 | 240 | 202301 | 117379 | 70608524 |
Cerebral haematoma | 15.16 | 9.88 | 51 | 202490 | 7327 | 70718576 |
Rhinorrhoea | 15.16 | 9.88 | 119 | 202422 | 66252 | 70659651 |
Bladder trabeculation | 15.13 | 9.88 | 6 | 202535 | 58 | 70725845 |
Conjunctivitis viral | 15.13 | 9.88 | 8 | 202533 | 157 | 70725746 |
Pneumothorax | 15.07 | 9.88 | 32 | 202509 | 25814 | 70700089 |
Trismus | 15.03 | 9.88 | 40 | 202501 | 5051 | 70720852 |
Post-traumatic neck syndrome | 14.99 | 9.88 | 23 | 202518 | 1950 | 70723953 |
Respiratory tract congestion | 14.93 | 9.88 | 17 | 202524 | 17636 | 70708267 |
Ulcer | 14.92 | 9.88 | 32 | 202509 | 25722 | 70700181 |
Inadequate analgesia | 14.91 | 9.88 | 35 | 202506 | 4087 | 70721816 |
Rash pruritic | 14.83 | 9.88 | 112 | 202429 | 62879 | 70663024 |
Kidney transplant rejection | 14.75 | 9.88 | 5 | 202536 | 9956 | 70715947 |
Immunodeficiency | 14.75 | 9.88 | 17 | 202524 | 17538 | 70708365 |
Cerebrovascular accident | 14.72 | 9.88 | 305 | 202236 | 143165 | 70582738 |
Hypnopompic hallucination | 14.69 | 9.88 | 6 | 202535 | 63 | 70725840 |
Tricuspid valve sclerosis | 14.66 | 9.88 | 5 | 202536 | 30 | 70725873 |
Feeling guilty | 14.59 | 9.88 | 15 | 202526 | 846 | 70725057 |
Sternal fracture | 14.58 | 9.88 | 25 | 202516 | 2326 | 70723577 |
Parkinsonian gait | 14.54 | 9.88 | 15 | 202526 | 849 | 70725054 |
Forced expiratory volume decreased | 14.54 | 9.88 | 50 | 202491 | 7264 | 70718639 |
Blood catecholamines increased | 14.53 | 9.88 | 5 | 202536 | 31 | 70725872 |
Hypoalbuminaemia | 14.52 | 9.88 | 20 | 202521 | 19102 | 70706801 |
Genital hypoaesthesia | 14.52 | 9.88 | 8 | 202533 | 171 | 70725732 |
Adverse drug reaction | 14.46 | 9.88 | 91 | 202450 | 53253 | 70672650 |
Labour complication | 14.45 | 9.88 | 6 | 202535 | 66 | 70725837 |
Neurological examination abnormal | 14.44 | 9.88 | 12 | 202529 | 514 | 70725389 |
Metastases to central nervous system | 14.40 | 9.88 | 13 | 202528 | 15021 | 70710882 |
Parasomnia | 14.38 | 9.88 | 12 | 202529 | 517 | 70725386 |
Foot deformity | 14.33 | 9.88 | 23 | 202518 | 20632 | 70705271 |
Apallic syndrome | 14.27 | 9.88 | 15 | 202526 | 868 | 70725035 |
Depersonalisation/derealisation disorder | 14.17 | 9.88 | 21 | 202520 | 1727 | 70724176 |
Tympanic membrane disorder | 14.15 | 9.88 | 8 | 202533 | 180 | 70725723 |
Tendonitis | 14.09 | 9.88 | 26 | 202515 | 22096 | 70703807 |
Eosinophilic myocarditis | 14.07 | 9.88 | 15 | 202526 | 882 | 70725021 |
Decreased appetite | 14.05 | 9.88 | 719 | 201822 | 304061 | 70421842 |
Multiple sclerosis relapse | 14.02 | 9.88 | 186 | 202355 | 42831 | 70683072 |
Skin texture abnormal | 13.97 | 9.88 | 11 | 202530 | 436 | 70725467 |
Anaemia of pregnancy | 13.84 | 9.88 | 6 | 202535 | 74 | 70725829 |
Selective mutism | 13.84 | 9.88 | 6 | 202535 | 74 | 70725829 |
Indifference | 13.83 | 9.88 | 9 | 202532 | 263 | 70725640 |
Flashback | 13.77 | 9.88 | 9 | 202532 | 265 | 70725638 |
Barotrauma | 13.76 | 9.88 | 8 | 202533 | 190 | 70725713 |
Haemorrhage | 13.74 | 9.88 | 163 | 202378 | 83652 | 70642251 |
Pulmonary fibrosis | 13.68 | 9.88 | 51 | 202490 | 34259 | 70691644 |
Regressive behaviour | 13.68 | 9.88 | 7 | 202534 | 128 | 70725775 |
Myopathy | 13.60 | 9.88 | 20 | 202521 | 18592 | 70707311 |
Escherichia infection | 13.52 | 9.88 | 16 | 202525 | 16315 | 70709588 |
Anal incontinence | 13.50 | 9.88 | 87 | 202454 | 16403 | 70709500 |
Device malfunction | 13.47 | 9.88 | 21 | 202520 | 19063 | 70706840 |
Food craving | 13.38 | 9.88 | 19 | 202522 | 1502 | 70724401 |
Movement disorder | 13.33 | 9.88 | 116 | 202425 | 24013 | 70701890 |
Alcohol use | 13.30 | 9.88 | 36 | 202505 | 4591 | 70721312 |
Chronic kidney disease | 13.24 | 9.88 | 111 | 202430 | 60946 | 70664957 |
Small intestinal obstruction | 13.18 | 9.88 | 32 | 202509 | 24623 | 70701280 |
Multiple sclerosis | 13.17 | 9.88 | 120 | 202421 | 25165 | 70700738 |
Violence-related symptom | 13.15 | 9.88 | 13 | 202528 | 699 | 70725204 |
Judgement impaired | 13.14 | 9.88 | 16 | 202525 | 1088 | 70724815 |
Pneumonia fungal | 13.09 | 9.88 | 6 | 202535 | 9947 | 70715956 |
Adverse event | 13.08 | 9.88 | 85 | 202456 | 49376 | 70676527 |
Device occlusion | 13.01 | 9.88 | 7 | 202534 | 10588 | 70715315 |
Femur fracture | 12.96 | 9.88 | 56 | 202485 | 36076 | 70689827 |
Peritonitis bacterial | 12.94 | 9.88 | 5 | 202536 | 9179 | 70716724 |
Hyponatraemic coma | 12.92 | 9.88 | 5 | 202536 | 45 | 70725858 |
Extrasystoles | 12.81 | 9.88 | 46 | 202495 | 6828 | 70719075 |
Angle closure glaucoma | 12.79 | 9.88 | 26 | 202515 | 2753 | 70723150 |
Metastases to lung | 12.76 | 9.88 | 17 | 202524 | 16467 | 70709436 |
Pseudophaeochromocytoma | 12.73 | 9.88 | 6 | 202535 | 91 | 70725812 |
Loose tooth | 12.72 | 9.88 | 27 | 202514 | 2947 | 70722956 |
Bipolar I disorder | 12.71 | 9.88 | 21 | 202520 | 1896 | 70724007 |
Hepatic cirrhosis | 12.70 | 9.88 | 45 | 202496 | 30686 | 70695217 |
Torsade de pointes | 12.70 | 9.88 | 92 | 202449 | 18024 | 70707879 |
Wrong technique in product usage process | 12.69 | 9.88 | 130 | 202411 | 68568 | 70657335 |
Hypnagogic hallucination | 12.64 | 9.88 | 7 | 202534 | 151 | 70725752 |
Injection site rash | 12.63 | 9.88 | 17 | 202524 | 16393 | 70709510 |
Osteoarthritis | 12.62 | 9.88 | 143 | 202398 | 74004 | 70651899 |
Pre-eclampsia | 12.60 | 9.88 | 44 | 202497 | 6441 | 70719462 |
Alcohol poisoning | 12.58 | 9.88 | 34 | 202507 | 4331 | 70721572 |
Renal aplasia | 12.56 | 9.88 | 6 | 202535 | 94 | 70725809 |
Partner stress | 12.55 | 9.88 | 9 | 202532 | 309 | 70725594 |
Limited symptom panic attack | 12.55 | 9.88 | 5 | 202536 | 49 | 70725854 |
Colitis ulcerative | 12.52 | 9.88 | 52 | 202489 | 33871 | 70692032 |
Ideas of reference | 12.52 | 9.88 | 7 | 202534 | 154 | 70725749 |
Consciousness fluctuating | 12.51 | 9.88 | 20 | 202521 | 1756 | 70724147 |
Inflammation | 12.51 | 9.88 | 154 | 202387 | 78511 | 70647392 |
Accident at work | 12.49 | 9.88 | 15 | 202526 | 1006 | 70724897 |
Unresponsive to stimuli | 12.43 | 9.88 | 213 | 202328 | 51718 | 70674185 |
Post-traumatic stress disorder | 12.38 | 9.88 | 34 | 202507 | 4373 | 70721530 |
Poor personal hygiene | 12.37 | 9.88 | 11 | 202530 | 517 | 70725386 |
Exposure via transplant | 12.34 | 9.88 | 4 | 202537 | 20 | 70725883 |
Rash maculo-papular | 12.31 | 9.88 | 89 | 202452 | 50456 | 70675447 |
Patella fracture | 12.24 | 9.88 | 19 | 202522 | 1627 | 70724276 |
Hypervolaemia | 12.22 | 9.88 | 65 | 202476 | 39641 | 70686262 |
Aplasia pure red cell | 12.21 | 9.88 | 3 | 202538 | 7371 | 70718532 |
Personality change | 12.21 | 9.88 | 54 | 202487 | 8816 | 70717087 |
Pleural rub | 12.20 | 9.88 | 5 | 202536 | 53 | 70725850 |
Multiple-drug resistance | 12.17 | 9.88 | 3 | 202538 | 7352 | 70718551 |
Bladder cancer | 12.15 | 9.88 | 19 | 202522 | 17223 | 70708680 |
Full blood count decreased | 12.04 | 9.88 | 32 | 202509 | 23886 | 70702017 |
Deja vu | 12.04 | 9.88 | 5 | 202536 | 55 | 70725848 |
Generalised anxiety disorder | 12.02 | 9.88 | 21 | 202520 | 1984 | 70723919 |
Withdrawal catatonia | 12.01 | 9.88 | 7 | 202534 | 167 | 70725736 |
Dropped head syndrome | 11.99 | 9.88 | 8 | 202533 | 244 | 70725659 |
Agoraphobia | 11.98 | 9.88 | 11 | 202530 | 539 | 70725364 |
Impulse-control disorder | 11.96 | 9.88 | 19 | 202522 | 1660 | 70724243 |
Large intestine perforation | 11.95 | 9.88 | 12 | 202529 | 13183 | 70712720 |
Ligament pain | 11.85 | 9.88 | 8 | 202533 | 249 | 70725654 |
Tuberculosis | 11.82 | 9.88 | 15 | 202526 | 14833 | 70711070 |
Dreamy state | 11.80 | 9.88 | 5 | 202536 | 58 | 70725845 |
Blood immunoglobulin E increased | 11.77 | 9.88 | 35 | 202506 | 4709 | 70721194 |
Anxiety disorder | 11.75 | 9.88 | 31 | 202510 | 3894 | 70722009 |
Morbihan disease | 11.73 | 9.88 | 4 | 202537 | 24 | 70725879 |
Hypokalaemia | 11.71 | 9.88 | 285 | 202256 | 130903 | 70595000 |
Head injury | 11.70 | 9.88 | 149 | 202392 | 33992 | 70691911 |
Enterocolitis | 11.70 | 9.88 | 12 | 202529 | 13054 | 70712849 |
Radiation inflammation | 11.68 | 9.88 | 11 | 202530 | 557 | 70725346 |
Allodynia | 11.67 | 9.88 | 17 | 202524 | 1376 | 70724527 |
Feeling of body temperature change | 11.66 | 9.88 | 36 | 202505 | 4943 | 70720960 |
Oesophagitis | 11.64 | 9.88 | 30 | 202511 | 22622 | 70703281 |
Hepatic encephalopathy | 11.59 | 9.88 | 29 | 202512 | 22089 | 70703814 |
Hypoxia | 11.58 | 9.88 | 192 | 202349 | 93152 | 70632751 |
Cholestatic liver injury | 11.55 | 9.88 | 32 | 202509 | 4136 | 70721767 |
Pseudomonas infection | 11.51 | 9.88 | 23 | 202518 | 18971 | 70706932 |
Psychiatric decompensation | 11.51 | 9.88 | 26 | 202515 | 2961 | 70722942 |
Osteomyelitis | 11.49 | 9.88 | 46 | 202495 | 30272 | 70695631 |
Grandiosity | 11.48 | 9.88 | 11 | 202530 | 569 | 70725334 |
Pain in jaw | 11.45 | 9.88 | 73 | 202468 | 42596 | 70683307 |
Blood glucose increased | 11.44 | 9.88 | 216 | 202325 | 102766 | 70623137 |
Urinary tract infection | 11.43 | 9.88 | 587 | 201954 | 248182 | 70477721 |
Bladder dilatation | 11.39 | 9.88 | 20 | 202521 | 1897 | 70724006 |
Pancreatic carcinoma | 11.39 | 9.88 | 12 | 202529 | 12892 | 70713011 |
Facial nerve disorder | 11.37 | 9.88 | 12 | 202529 | 698 | 70725205 |
Type 2 diabetes mellitus | 11.36 | 9.88 | 183 | 202358 | 43897 | 70682006 |
Neuropsychiatric syndrome | 11.33 | 9.88 | 6 | 202535 | 118 | 70725785 |
Magical thinking | 11.31 | 9.88 | 3 | 202538 | 6 | 70725897 |
Creutzfeldt-Jakob disease | 11.28 | 9.88 | 7 | 202534 | 188 | 70725715 |
Acidosis | 11.26 | 9.88 | 90 | 202451 | 18173 | 70707730 |
Product formulation issue | 11.24 | 9.88 | 13 | 202528 | 837 | 70725066 |
Therapy interrupted | 11.16 | 9.88 | 35 | 202506 | 24767 | 70701136 |
Antiphospholipid antibodies | 11.16 | 9.88 | 6 | 202535 | 122 | 70725781 |
Gun shot wound | 11.14 | 9.88 | 15 | 202526 | 1128 | 70724775 |
Anuria | 11.13 | 9.88 | 95 | 202446 | 19558 | 70706345 |
Central nervous system necrosis | 11.12 | 9.88 | 8 | 202533 | 276 | 70725627 |
Premature delivery | 11.11 | 9.88 | 28 | 202513 | 21276 | 70704627 |
Blood lactic acid increased | 11.10 | 9.88 | 62 | 202479 | 11111 | 70714792 |
Infective pulmonary exacerbation of cystic fibrosis | 11.08 | 9.88 | 11 | 202530 | 12147 | 70713756 |
Snoring | 11.07 | 9.88 | 35 | 202506 | 4869 | 70721034 |
Squamous cell carcinoma of skin | 11.02 | 9.88 | 12 | 202529 | 12700 | 70713203 |
Acute respiratory failure | 11.00 | 9.88 | 99 | 202442 | 53566 | 70672337 |
Disorganised speech | 10.97 | 9.88 | 19 | 202522 | 1782 | 70724121 |
Amenorrhoea | 10.95 | 9.88 | 44 | 202497 | 6886 | 70719017 |
Intestinal anastomosis complication | 10.87 | 9.88 | 8 | 202533 | 286 | 70725617 |
Platelet aggregation abnormal | 10.86 | 9.88 | 4 | 202537 | 31 | 70725872 |
Colon cancer | 10.83 | 9.88 | 15 | 202526 | 14291 | 70711612 |
Appendicectomy | 10.78 | 9.88 | 22 | 202519 | 2336 | 70723567 |
Hyperphagia | 10.78 | 9.88 | 22 | 202519 | 2337 | 70723566 |
Pseudohyponatraemia | 10.77 | 9.88 | 6 | 202535 | 131 | 70725772 |
Pulmonary vein occlusion | 10.77 | 9.88 | 6 | 202535 | 131 | 70725772 |
Tic | 10.77 | 9.88 | 24 | 202517 | 2709 | 70723194 |
Mechanical urticaria | 10.76 | 9.88 | 9 | 202532 | 389 | 70725514 |
Gonadotrophin deficiency | 10.75 | 9.88 | 4 | 202537 | 32 | 70725871 |
Device issue | 10.74 | 9.88 | 34 | 202507 | 23991 | 70701912 |
Accidental overdose | 10.68 | 9.88 | 150 | 202391 | 34971 | 70690932 |
Slow speech | 10.68 | 9.88 | 21 | 202520 | 2171 | 70723732 |
Coronary artery disease | 10.67 | 9.88 | 121 | 202420 | 62615 | 70663288 |
Respiratory rate decreased | 10.67 | 9.88 | 34 | 202507 | 4748 | 70721155 |
Alcohol withdrawal syndrome | 10.67 | 9.88 | 19 | 202522 | 1822 | 70724081 |
Polyarthritis | 10.67 | 9.88 | 9 | 202532 | 10747 | 70715156 |
Sleep talking | 10.67 | 9.88 | 14 | 202527 | 1027 | 70724876 |
Stereotypy | 10.67 | 9.88 | 13 | 202528 | 885 | 70725018 |
Norepinephrine increased | 10.66 | 9.88 | 5 | 202536 | 75 | 70725828 |
Juvenile myoclonic epilepsy | 10.66 | 9.88 | 5 | 202536 | 75 | 70725828 |
Knee arthroplasty | 10.64 | 9.88 | 56 | 202485 | 34245 | 70691658 |
Skull fractured base | 10.64 | 9.88 | 8 | 202533 | 296 | 70725607 |
Hyperemesis gravidarum | 10.53 | 9.88 | 9 | 202532 | 401 | 70725502 |
Tanning | 10.48 | 9.88 | 5 | 202536 | 78 | 70725825 |
Hypotonia neonatal | 10.48 | 9.88 | 5 | 202536 | 78 | 70725825 |
Cystic lymphangioma | 10.45 | 9.88 | 3 | 202538 | 9 | 70725894 |
Treatment noncompliance | 10.42 | 9.88 | 189 | 202352 | 46385 | 70679518 |
Coagulation factor VII level decreased | 10.39 | 9.88 | 7 | 202534 | 217 | 70725686 |
Marital problem | 10.39 | 9.88 | 7 | 202534 | 217 | 70725686 |
Aortic stenosis | 10.37 | 9.88 | 3 | 202538 | 6613 | 70719290 |
Coordination abnormal | 10.36 | 9.88 | 80 | 202461 | 15986 | 70709917 |
Accidental exposure to product | 10.36 | 9.88 | 43 | 202498 | 28008 | 70697895 |
Action tremor | 10.32 | 9.88 | 9 | 202532 | 412 | 70725491 |
Skin disorder | 10.32 | 9.88 | 48 | 202493 | 30309 | 70695594 |
Vascular device infection | 10.32 | 9.88 | 5 | 202536 | 8025 | 70717878 |
Candida infection | 10.30 | 9.88 | 57 | 202484 | 34416 | 70691487 |
Human chorionic gonadotropin positive | 10.24 | 9.88 | 4 | 202537 | 37 | 70725866 |
Device leakage | 10.24 | 9.88 | 7 | 202534 | 9301 | 70716602 |
Salivary gland disorder | 10.23 | 9.88 | 8 | 202533 | 314 | 70725589 |
Constricted affect | 10.21 | 9.88 | 3 | 202538 | 10 | 70725893 |
Rectal fissure | 10.21 | 9.88 | 12 | 202529 | 786 | 70725117 |
Opiates positive | 10.19 | 9.88 | 13 | 202528 | 927 | 70724976 |
Renal injury | 10.18 | 9.88 | 19 | 202522 | 16075 | 70709828 |
Staring | 10.17 | 9.88 | 22 | 202519 | 2434 | 70723469 |
Rib fracture | 10.16 | 9.88 | 114 | 202427 | 25242 | 70700661 |
Right ventricular systolic pressure decreased | 10.15 | 9.88 | 5 | 202536 | 84 | 70725819 |
Clumsiness | 10.14 | 9.88 | 24 | 202517 | 2818 | 70723085 |
Anaphylactic shock | 10.11 | 9.88 | 53 | 202488 | 32437 | 70693466 |
Disability | 10.10 | 9.88 | 17 | 202524 | 14966 | 70710937 |
Blood triglycerides increased | 10.08 | 9.88 | 93 | 202448 | 19571 | 70706332 |
Psychomotor skills impaired | 10.06 | 9.88 | 31 | 202510 | 4253 | 70721650 |
Joint effusion | 10.03 | 9.88 | 18 | 202523 | 15459 | 70710444 |
Chills | 10.00 | 9.88 | 326 | 202215 | 144460 | 70581443 |
Large cell lung cancer metastatic | 9.99 | 9.88 | 3 | 202538 | 11 | 70725892 |
Radius fracture | 9.98 | 9.88 | 26 | 202515 | 3240 | 70722663 |
Ovarian cancer stage III | 9.98 | 9.88 | 7 | 202534 | 232 | 70725671 |
Victim of crime | 9.98 | 9.88 | 9 | 202532 | 431 | 70725472 |
Cartilage injury | 9.97 | 9.88 | 16 | 202525 | 1410 | 70724493 |
Intellectual disability | 9.97 | 9.88 | 14 | 202527 | 1096 | 70724807 |
Anorexia nervosa | 9.93 | 9.88 | 7 | 202534 | 234 | 70725669 |
Atrioventricular block | 9.91 | 9.88 | 13 | 202528 | 12675 | 70713228 |
Alpha 2 globulin increased | 9.91 | 9.88 | 6 | 202535 | 154 | 70725749 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Selective eating disorder | 42.74 | 25.54 | 91 | 2038 | 1137 | 86526 |
Premature baby | 28.97 | 25.54 | 31 | 2098 | 3897 | 83766 |
Hypotonia neonatal | 28.54 | 25.54 | 59 | 2070 | 717 | 86946 |
Mitral valve incompetence | 27.87 | 25.54 | 12 | 2117 | 7 | 87656 |
Neonatal asphyxia | 27.43 | 25.54 | 22 | 2107 | 89 | 87574 |
Source | Code | Description |
---|---|---|
ATC | N06AX16 | NERVOUS SYSTEM PSYCHOANALEPTICS ANTIDEPRESSANTS Other antidepressants |
FDA MoA | N0000000102 | Norepinephrine Uptake Inhibitors |
FDA MoA | N0000000109 | Serotonin Uptake Inhibitors |
MeSH PA | D000928 | Antidepressive Agents |
MeSH PA | D018687 | Antidepressive Agents, Second-Generation |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D049990 | Membrane Transport Modulators |
MeSH PA | D018377 | Neurotransmitter Agents |
MeSH PA | D014179 | Neurotransmitter Uptake Inhibitors |
MeSH PA | D011619 | Psychotropic Drugs |
MeSH PA | D000068760 | Serotonin and Noradrenaline Reuptake Inhibitors |
CHEBI has role | CHEBI:35469 | antidepressants |
CHEBI has role | CHEBI:35640 | adrenergic uptake inhibitors |
CHEBI has role | CHEBI:35703 | Xenobiotic |
CHEBI has role | CHEBI:50949 | SSRI |
CHEBI has role | CHEBI:51039 | dopamine reuptake inhibitor |
CHEBI has role | CHEBI:78298 | environmental contaminants |
FDA EPC | N0000175749 | Serotonin and Norepinephrine Reuptake Inhibitor |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Generalized anxiety disorder | indication | 21897009 | DOID:14320 |
Social phobia | indication | 25501002 | DOID:11257 |
Major depressive disorder | indication | 370143000 | |
Panic disorder | indication | 371631005 | DOID:594 |
Posttraumatic stress disorder | off-label use | 47505003 | DOID:2055 |
Menopausal flushing | off-label use | 198436008 | |
Neuropathic pain | off-label use | 247398009 | |
Ocular hypertension | contraindication | 4210003 | DOID:9282 |
Suicidal thoughts | contraindication | 6471006 | |
Dependent drug abuse | contraindication | 6525002 | |
Hypercholesterolemia | contraindication | 13644009 | |
Bipolar disorder | contraindication | 13746004 | DOID:3312 |
Neuroleptic malignant syndrome | contraindication | 15244003 | DOID:14464 |
Cirrhosis of liver | contraindication | 19943007 | DOID:5082 |
Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
Upper gastrointestinal hemorrhage | contraindication | 37372002 | |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Chronic heart failure | contraindication | 48447003 | |
Disorder of cardiovascular system | contraindication | 49601007 | DOID:1287 |
Syndrome of inappropriate vasopressin secretion | contraindication | 55004003 | DOID:3401 |
Hepatic failure | contraindication | 59927004 | |
Cerebrovascular disease | contraindication | 62914000 | DOID:6713 |
Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
Substance abuse | contraindication | 66214007 | |
Weight loss | contraindication | 89362005 | |
Hyponatremia | contraindication | 89627008 | |
Prolonged QT interval | contraindication | 111975006 | |
Seizure disorder | contraindication | 128613002 | |
Bleeding | contraindication | 131148009 | |
Impaired renal function disorder | contraindication | 197663003 | |
Mania | contraindication | 231494001 | |
Hypomania | contraindication | 231496004 | |
Interstitial lung disease | contraindication | 233703007 | DOID:3082 |
Disease of liver | contraindication | 235856003 | DOID:409 |
Hypertriglyceridemia | contraindication | 302870006 | |
Serotonin syndrome | contraindication | 371089000 | |
Angle-closure glaucoma | contraindication | 392291006 | DOID:13550 |
Myocardial infarction in recovery phase | contraindication | 418044006 | |
Congenital long QT syndrome | contraindication | 442917000 | |
Hypertensive urgency | contraindication | 443482000 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 9.33 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter | Transporter | INHIBITOR | Kd | 8.05 | WOMBAT-PK | CHEMBL | |||
Sodium-dependent noradrenaline transporter | Transporter | INHIBITOR | Kd | 5.98 | WOMBAT-PK | CHEMBL | |||
5-hydroxytryptamine receptor 2A | GPCR | Ki | 5.65 | PDSP | |||||
5-hydroxytryptamine receptor 2C | GPCR | Ki | 5.70 | PDSP | |||||
5-hydroxytryptamine receptor 6 | GPCR | Ki | 5.55 | PDSP | |||||
Sodium-dependent dopamine transporter | Transporter | Ki | 5.44 | CHEMBL | |||||
Alpha-1A adrenergic receptor | GPCR | IC50 | 7.05 | CHEMBL | |||||
Sodium-dependent serotonin transporter | Transporter | Ki | 7.60 | CHEMBL | |||||
Sodium-dependent dopamine transporter | Transporter | Ki | 6.44 | CHEMBL | |||||
Transporter | Transporter | Ki | 6.86 | CHEMBL | |||||
Transporter | Transporter | IC50 | 6.19 | CHEMBL |
ID | Source |
---|---|
4023901 | VUID |
N0000021906 | NUI |
D00821 | KEGG_DRUG |
99300-78-4 | SECONDARY_CAS_RN |
4020846 | VANDF |
4023901 | VANDF |
C0078569 | UMLSCUI |
CHEBI:9943 | CHEBI |
CHEMBL637 | ChEMBL_ID |
DB00285 | DRUGBANK_ID |
CHEMBL1201066 | ChEMBL_ID |
D000069470 | MESH_DESCRIPTOR_UI |
5656 | PUBCHEM_CID |
7321 | IUPHAR_LIGAND_ID |
6358 | INN_ID |
GRZ5RCB1QG | UNII |
151692 | RXNORM |
5669 | MMSL |
594 | MMSL |
87651 | MMSL |
d03181 | MMSL |
004428 | NDDF |
004429 | NDDF |
108432009 | SNOMEDCT_US |
108434005 | SNOMEDCT_US |
372490001 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Effexor XR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0833 | CAPSULE, EXTENDED RELEASE | 75 mg | ORAL | NDA | 40 sections |
Effexor XR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0833 | CAPSULE, EXTENDED RELEASE | 75 mg | ORAL | NDA | 40 sections |
Effexor XR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0836 | CAPSULE, EXTENDED RELEASE | 150 mg | ORAL | NDA | 40 sections |
Effexor XR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0836 | CAPSULE, EXTENDED RELEASE | 150 mg | ORAL | NDA | 40 sections |
Effexor XR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0837 | CAPSULE, EXTENDED RELEASE | 37.50 mg | ORAL | NDA | 40 sections |
Effexor XR | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0837 | CAPSULE, EXTENDED RELEASE | 37.50 mg | ORAL | NDA | 40 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7384 | CAPSULE, EXTENDED RELEASE | 37.50 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7384 | CAPSULE, EXTENDED RELEASE | 37.50 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7385 | CAPSULE, EXTENDED RELEASE | 75 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7385 | CAPSULE, EXTENDED RELEASE | 75 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7386 | CAPSULE, EXTENDED RELEASE | 150 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-7386 | CAPSULE, EXTENDED RELEASE | 150 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9147 | TABLET | 25 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9147 | TABLET | 25 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9148 | TABLET | 37.50 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9148 | TABLET | 37.50 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9149 | TABLET | 50 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9149 | TABLET | 50 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9157 | TABLET | 75 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9157 | TABLET | 75 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9163 | TABLET | 100 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-9163 | TABLET | 100 mg | ORAL | ANDA | 33 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-2604 | TABLET | 150 mg | ORAL | ANDA | 30 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-2605 | TABLET | 225 mg | ORAL | ANDA | 30 sections |
Venlafaxine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-2606 | TABLET | 75 mg | ORAL | ANDA | 29 sections |
Venlafaxine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-6566 | TABLET | 37.50 mg | ORAL | ANDA | 25 sections |
Venlafaxine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-6567 | TABLET | 75 mg | ORAL | ANDA | 23 sections |
Venlafaxine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7557 | TABLET | 50 mg | ORAL | ANDA | 23 sections |
Venlafaxine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7558 | TABLET | 100 mg | ORAL | ANDA | 23 sections |
Venlafaxine Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7621 | CAPSULE, EXTENDED RELEASE | 75 mg | ORAL | ANDA | 32 sections |