Stem definition | Drug id | CAS RN |
---|---|---|
2803 | 99-66-1 |
Dose | Unit | Route |
---|---|---|
1.50 | g | O |
1.50 | g | P |
1.50 | g | R |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 1.30 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 1.80 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 289.15 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 99 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 0.14 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 0.16 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.08 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 12 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Feb. 28, 1978 | FDA | ABBVIE |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Seizure | 1701.52 | 10.27 | 1669 | 110079 | 116205 | 50377171 |
Hyperammonaemia | 1128.48 | 10.27 | 416 | 111332 | 4308 | 50489068 |
Hyperammonaemic encephalopathy | 1077.05 | 10.27 | 325 | 111423 | 1674 | 50491702 |
Drug interaction | 1028.99 | 10.27 | 1690 | 110058 | 197931 | 50295445 |
Status epilepticus | 764.38 | 10.27 | 435 | 111313 | 12971 | 50480405 |
Foetal anticonvulsant syndrome | 640.32 | 10.27 | 165 | 111583 | 407 | 50492969 |
Somnolence | 601.21 | 10.27 | 1160 | 110588 | 153825 | 50339551 |
Epilepsy | 566.67 | 10.27 | 431 | 111317 | 21136 | 50472240 |
Toxicity to various agents | 509.42 | 10.27 | 1312 | 110436 | 211187 | 50282189 |
Aggression | 502.59 | 10.27 | 398 | 111350 | 20718 | 50472658 |
Sopor | 486.73 | 10.27 | 381 | 111367 | 19498 | 50473878 |
Arthralgia | 460.66 | 10.27 | 197 | 111551 | 438505 | 50054871 |
Dysmorphism | 459.78 | 10.27 | 175 | 111573 | 1992 | 50491384 |
Pain | 458.36 | 10.27 | 366 | 111382 | 578537 | 49914839 |
Psychotic disorder | 443.25 | 10.27 | 375 | 111373 | 21437 | 50471939 |
Ammonia increased | 431.00 | 10.27 | 203 | 111545 | 4038 | 50489338 |
Intentional overdose | 426.59 | 10.27 | 604 | 111144 | 61900 | 50431476 |
Foetal exposure during pregnancy | 426.52 | 10.27 | 405 | 111343 | 26954 | 50466422 |
Generalised tonic-clonic seizure | 422.64 | 10.27 | 396 | 111352 | 25914 | 50467462 |
Multiple-drug resistance | 394.33 | 10.27 | 177 | 111571 | 3137 | 50490239 |
Extrapyramidal disorder | 390.58 | 10.27 | 271 | 111477 | 11499 | 50481877 |
Coma | 387.17 | 10.27 | 549 | 111199 | 56330 | 50437046 |
Overdose | 379.55 | 10.27 | 741 | 111007 | 98986 | 50394390 |
Drug level increased | 368.55 | 10.27 | 320 | 111428 | 18948 | 50474428 |
Rheumatoid arthritis | 356.83 | 10.27 | 23 | 111725 | 202527 | 50290849 |
Granulocytopenia | 348.14 | 10.27 | 188 | 111560 | 5043 | 50488333 |
Tremor | 347.55 | 10.27 | 777 | 110971 | 114126 | 50379250 |
Mania | 347.44 | 10.27 | 245 | 111503 | 10671 | 50482705 |
Joint swelling | 346.30 | 10.27 | 62 | 111686 | 245224 | 50248152 |
Speech disorder developmental | 332.93 | 10.27 | 100 | 111648 | 505 | 50492871 |
Neuroleptic malignant syndrome | 329.42 | 10.27 | 239 | 111509 | 10891 | 50482485 |
Intentional self-injury | 326.19 | 10.27 | 324 | 111424 | 22788 | 50470588 |
Parkinsonism | 320.36 | 10.27 | 215 | 111533 | 8632 | 50484744 |
Suicide attempt | 318.15 | 10.27 | 476 | 111272 | 51256 | 50442120 |
Petit mal epilepsy | 317.60 | 10.27 | 152 | 111596 | 3137 | 50490239 |
Fatigue | 298.98 | 10.27 | 706 | 111042 | 706895 | 49786481 |
Sedation | 288.57 | 10.27 | 347 | 111401 | 30263 | 50463113 |
Drug abuse | 287.47 | 10.27 | 492 | 111256 | 59354 | 50434022 |
Infusion related reaction | 282.31 | 10.27 | 25 | 111723 | 169532 | 50323844 |
Developmental delay | 279.94 | 10.27 | 106 | 111642 | 1188 | 50492188 |
Abnormal behaviour | 276.33 | 10.27 | 275 | 111473 | 19383 | 50473993 |
Dyspnoea | 271.73 | 10.27 | 498 | 111250 | 547110 | 49946266 |
Agitation | 271.17 | 10.27 | 450 | 111298 | 52934 | 50440442 |
Learning disorder | 259.35 | 10.27 | 83 | 111665 | 535 | 50492841 |
Drug reaction with eosinophilia and systemic symptoms | 257.81 | 10.27 | 316 | 111432 | 28108 | 50465268 |
Arthropathy | 255.66 | 10.27 | 26 | 111722 | 157880 | 50335496 |
Abdominal discomfort | 250.70 | 10.27 | 99 | 111649 | 231542 | 50261834 |
Depressed level of consciousness | 250.67 | 10.27 | 428 | 111320 | 51525 | 50441851 |
Ataxia | 243.74 | 10.27 | 219 | 111529 | 13567 | 50479809 |
Peripheral swelling | 243.43 | 10.27 | 76 | 111672 | 205860 | 50287516 |
Cognitive disorder | 237.70 | 10.27 | 382 | 111366 | 43741 | 50449635 |
Drug level decreased | 232.31 | 10.27 | 157 | 111591 | 6376 | 50487000 |
Autism spectrum disorder | 229.10 | 10.27 | 78 | 111670 | 625 | 50492751 |
Swelling | 228.86 | 10.27 | 79 | 111669 | 200793 | 50292583 |
Contraindicated product administered | 222.77 | 10.27 | 32 | 111716 | 148926 | 50344450 |
Diarrhoea | 220.54 | 10.27 | 623 | 111125 | 587853 | 49905523 |
Schizoaffective disorder | 213.16 | 10.27 | 102 | 111646 | 2104 | 50491272 |
Intellectual disability | 212.24 | 10.27 | 76 | 111672 | 718 | 50492658 |
Electrocardiogram QT prolonged | 208.80 | 10.27 | 395 | 111353 | 51491 | 50441885 |
Anticonvulsant drug level increased | 207.43 | 10.27 | 87 | 111661 | 1297 | 50492079 |
Abortion spontaneous | 205.28 | 10.27 | 347 | 111401 | 41425 | 50451951 |
Antipsychotic drug level increased | 202.05 | 10.27 | 110 | 111638 | 2999 | 50490377 |
Hand deformity | 201.42 | 10.27 | 4 | 111744 | 100195 | 50393181 |
Hypernatraemia | 199.12 | 10.27 | 141 | 111607 | 6180 | 50487196 |
Salivary hypersecretion | 196.09 | 10.27 | 142 | 111606 | 6449 | 50486927 |
Systemic lupus erythematosus | 193.03 | 10.27 | 38 | 111710 | 140584 | 50352792 |
Glossodynia | 187.10 | 10.27 | 19 | 111729 | 115550 | 50377826 |
Disturbance in attention | 186.03 | 10.27 | 283 | 111465 | 30903 | 50462473 |
Sinusitis | 179.40 | 10.27 | 76 | 111672 | 170482 | 50322894 |
Myoclonic epilepsy | 179.38 | 10.27 | 71 | 111677 | 904 | 50492472 |
Sudden unexplained death in epilepsy | 172.39 | 10.27 | 51 | 111697 | 242 | 50493134 |
Encephalopathy | 172.25 | 10.27 | 285 | 111463 | 33426 | 50459950 |
Nasopharyngitis | 170.27 | 10.27 | 108 | 111640 | 192819 | 50300557 |
Anticonvulsant drug level decreased | 170.12 | 10.27 | 72 | 111676 | 1099 | 50492277 |
Pain in extremity | 169.78 | 10.27 | 212 | 111536 | 272653 | 50220723 |
Anticonvulsant drug level above therapeutic | 167.49 | 10.27 | 57 | 111691 | 456 | 50492920 |
Drug intolerance | 165.83 | 10.27 | 144 | 111604 | 218960 | 50274416 |
Nausea | 164.83 | 10.27 | 902 | 110846 | 704496 | 49788880 |
Schizophrenia | 164.41 | 10.27 | 134 | 111614 | 7263 | 50486113 |
Hallucination, auditory | 163.69 | 10.27 | 157 | 111591 | 10571 | 50482805 |
Disorientation | 162.84 | 10.27 | 286 | 111462 | 35198 | 50458178 |
Hypothermia | 161.33 | 10.27 | 164 | 111584 | 11852 | 50481524 |
Irritability | 161.19 | 10.27 | 252 | 111496 | 28174 | 50465202 |
Psychomotor retardation | 160.83 | 10.27 | 98 | 111650 | 3320 | 50490056 |
Altered state of consciousness | 160.19 | 10.27 | 219 | 111529 | 21691 | 50471685 |
Hypotonia | 155.32 | 10.27 | 135 | 111613 | 7999 | 50485377 |
Psychomotor skills impaired | 153.80 | 10.27 | 80 | 111668 | 1984 | 50491392 |
Discomfort | 153.62 | 10.27 | 27 | 111721 | 108353 | 50385023 |
Behaviour disorder | 151.33 | 10.27 | 83 | 111665 | 2297 | 50491079 |
Hypersensitivity | 149.22 | 10.27 | 153 | 111595 | 215008 | 50278368 |
Electroencephalogram abnormal | 148.63 | 10.27 | 94 | 111654 | 3405 | 50489971 |
Treatment noncompliance | 147.50 | 10.27 | 250 | 111498 | 29900 | 50463476 |
Stevens-Johnson syndrome | 145.00 | 10.27 | 208 | 111540 | 21544 | 50471832 |
Learning disability | 144.68 | 10.27 | 42 | 111706 | 184 | 50493192 |
Drug ineffective for unapproved indication | 144.07 | 10.27 | 205 | 111543 | 21076 | 50472300 |
Delusion | 143.26 | 10.27 | 145 | 111603 | 10424 | 50482952 |
Congenital nose malformation | 142.61 | 10.27 | 44 | 111704 | 247 | 50493129 |
Drug withdrawal convulsions | 141.29 | 10.27 | 66 | 111682 | 1287 | 50492089 |
Catatonia | 138.15 | 10.27 | 92 | 111656 | 3644 | 50489732 |
Bipolar disorder | 136.86 | 10.27 | 116 | 111632 | 6641 | 50486735 |
Partial seizures | 136.11 | 10.27 | 101 | 111647 | 4764 | 50488612 |
Back pain | 130.57 | 10.27 | 177 | 111571 | 219853 | 50273523 |
Cough | 130.55 | 10.27 | 207 | 111541 | 241057 | 50252319 |
Educational problem | 127.23 | 10.27 | 43 | 111705 | 336 | 50493040 |
Language disorder | 126.67 | 10.27 | 67 | 111681 | 1721 | 50491655 |
Exposure during pregnancy | 126.41 | 10.27 | 566 | 111182 | 120449 | 50372927 |
Paradoxical drug reaction | 125.75 | 10.27 | 86 | 111662 | 3561 | 50489815 |
Suicidal ideation | 125.06 | 10.27 | 335 | 111413 | 55050 | 50438326 |
Wound | 124.97 | 10.27 | 39 | 111709 | 105755 | 50387621 |
Pruritus | 123.80 | 10.27 | 277 | 111471 | 283291 | 50210085 |
Headache | 122.26 | 10.27 | 640 | 111108 | 505895 | 49987481 |
Drug resistance | 119.91 | 10.27 | 177 | 111571 | 18812 | 50474564 |
Dysarthria | 119.74 | 10.27 | 259 | 111489 | 37144 | 50456232 |
Fanconi syndrome | 117.34 | 10.27 | 55 | 111693 | 1081 | 50492295 |
Bradyphrenia | 117.25 | 10.27 | 102 | 111646 | 6050 | 50487326 |
Meningomyelocele | 117.14 | 10.27 | 45 | 111703 | 526 | 50492850 |
Psychomotor hyperactivity | 114.17 | 10.27 | 121 | 111627 | 9180 | 50484196 |
Hypomania | 111.64 | 10.27 | 87 | 111661 | 4418 | 50488958 |
Myoclonus | 110.89 | 10.27 | 148 | 111600 | 14322 | 50479054 |
Product substitution issue | 109.61 | 10.27 | 145 | 111603 | 13912 | 50479464 |
Therapeutic product effect decreased | 109.59 | 10.27 | 84 | 111664 | 135966 | 50357410 |
Muscle rigidity | 108.66 | 10.27 | 121 | 111627 | 9708 | 50483668 |
Completed suicide | 108.41 | 10.27 | 576 | 111172 | 131313 | 50362063 |
Psychogenic seizure | 108.36 | 10.27 | 58 | 111690 | 1527 | 50491849 |
Pneumonia aspiration | 107.72 | 10.27 | 222 | 111526 | 30782 | 50462594 |
Injection site pain | 106.64 | 10.27 | 56 | 111692 | 110968 | 50382408 |
Congenital hand malformation | 104.86 | 10.27 | 35 | 111713 | 262 | 50493114 |
Anticonvulsant drug level below therapeutic | 104.57 | 10.27 | 42 | 111706 | 557 | 50492819 |
Talipes | 103.05 | 10.27 | 54 | 111694 | 1360 | 50492016 |
Congenital foot malformation | 102.64 | 10.27 | 32 | 111716 | 187 | 50493189 |
Blood creatine phosphokinase increased | 101.43 | 10.27 | 197 | 111551 | 26170 | 50467206 |
Tardive dyskinesia | 100.74 | 10.27 | 101 | 111647 | 7178 | 50486198 |
Impaired healing | 99.71 | 10.27 | 17 | 111731 | 69769 | 50423607 |
Febrile neutropenia | 98.73 | 10.27 | 46 | 111702 | 97621 | 50395755 |
Respiratory depression | 98.48 | 10.27 | 127 | 111621 | 11883 | 50481493 |
Thrombocytopenia | 98.46 | 10.27 | 548 | 111200 | 127125 | 50366251 |
Mental disorder | 97.98 | 10.27 | 175 | 111573 | 21816 | 50471560 |
Product residue present | 97.75 | 10.27 | 74 | 111674 | 3598 | 50489778 |
Akathisia | 97.39 | 10.27 | 105 | 111643 | 8124 | 50485252 |
Arthritis | 97.13 | 10.27 | 35 | 111713 | 86686 | 50406690 |
Atonic seizures | 96.87 | 10.27 | 40 | 111708 | 572 | 50492804 |
Hyperprolactinaemia | 96.70 | 10.27 | 71 | 111677 | 3294 | 50490082 |
Rash | 96.03 | 10.27 | 570 | 111178 | 436901 | 50056475 |
Carnitine deficiency | 94.79 | 10.27 | 28 | 111720 | 132 | 50493244 |
Cerebral atrophy | 93.21 | 10.27 | 79 | 111669 | 4522 | 50488854 |
Confusional state | 93.18 | 10.27 | 716 | 111032 | 185212 | 50308164 |
Stupor | 92.72 | 10.27 | 71 | 111677 | 3512 | 50489864 |
Nystagmus | 91.75 | 10.27 | 85 | 111663 | 5476 | 50487900 |
Infection | 90.12 | 10.27 | 152 | 111596 | 172802 | 50320574 |
Speech disorder | 89.47 | 10.27 | 224 | 111524 | 35324 | 50458052 |
Rhabdomyolysis | 89.04 | 10.27 | 237 | 111511 | 38790 | 50454586 |
Herpes zoster | 87.42 | 10.27 | 24 | 111724 | 70762 | 50422614 |
Psychiatric symptom | 85.54 | 10.27 | 75 | 111673 | 4495 | 50488881 |
Stomatitis | 84.93 | 10.27 | 60 | 111688 | 101284 | 50392092 |
Injection site erythema | 84.33 | 10.27 | 30 | 111718 | 74906 | 50418470 |
Low set ears | 84.25 | 10.27 | 29 | 111719 | 241 | 50493135 |
Anaemia | 82.95 | 10.27 | 283 | 111465 | 252173 | 50241203 |
Pericarditis | 82.77 | 10.27 | 35 | 111713 | 78654 | 50414722 |
Hypertelorism | 82.47 | 10.27 | 32 | 111716 | 385 | 50492991 |
Persecutory delusion | 81.62 | 10.27 | 56 | 111692 | 2331 | 50491045 |
Dyskinesia | 81.37 | 10.27 | 186 | 111562 | 27675 | 50465701 |
Delirium | 81.20 | 10.27 | 226 | 111522 | 37966 | 50455410 |
Neuropathy peripheral | 80.14 | 10.27 | 58 | 111690 | 96699 | 50396677 |
Abdominal pain upper | 78.47 | 10.27 | 145 | 111603 | 159164 | 50334212 |
Arnold-Chiari malformation | 77.40 | 10.27 | 32 | 111716 | 459 | 50492917 |
Focal dyscognitive seizures | 77.06 | 10.27 | 57 | 111691 | 2675 | 50490701 |
Motor developmental delay | 76.27 | 10.27 | 23 | 111725 | 118 | 50493258 |
Toxic epidermal necrolysis | 76.10 | 10.27 | 153 | 111595 | 20839 | 50472537 |
Cardiac failure congestive | 76.07 | 10.27 | 46 | 111702 | 84336 | 50409040 |
Loss of consciousness | 75.88 | 10.27 | 441 | 111307 | 103912 | 50389464 |
Helicobacter infection | 75.84 | 10.27 | 10 | 111738 | 49692 | 50443684 |
Propofol infusion syndrome | 75.78 | 10.27 | 36 | 111712 | 730 | 50492646 |
Osteoarthritis | 74.62 | 10.27 | 29 | 111719 | 68577 | 50424799 |
Folliculitis | 73.56 | 10.27 | 3 | 111745 | 39222 | 50454154 |
Tonic convulsion | 73.18 | 10.27 | 40 | 111708 | 1099 | 50492277 |
Strabismus | 72.37 | 10.27 | 47 | 111701 | 1783 | 50491593 |
Chest pain | 72.13 | 10.27 | 179 | 111569 | 176703 | 50316673 |
Ear malformation | 72.10 | 10.27 | 24 | 111724 | 178 | 50493198 |
Intentional product use issue | 72.09 | 10.27 | 40 | 111708 | 76878 | 50416498 |
Urticaria | 72.06 | 10.27 | 109 | 111639 | 129452 | 50363924 |
Impulsive behaviour | 71.68 | 10.27 | 43 | 111705 | 1415 | 50491961 |
Pleurothotonus | 70.87 | 10.27 | 41 | 111707 | 1260 | 50492116 |
Microcephaly | 70.63 | 10.27 | 35 | 111713 | 781 | 50492595 |
Mental impairment | 69.97 | 10.27 | 108 | 111640 | 11936 | 50481440 |
Spina bifida | 69.70 | 10.27 | 33 | 111715 | 664 | 50492712 |
Muscle injury | 69.06 | 10.27 | 3 | 111745 | 37108 | 50456268 |
Affect lability | 68.89 | 10.27 | 92 | 111656 | 8906 | 50484470 |
Musculoskeletal stiffness | 68.68 | 10.27 | 111 | 111637 | 128370 | 50365006 |
Alopecia | 68.65 | 10.27 | 293 | 111455 | 244754 | 50248622 |
Leukopenia | 68.32 | 10.27 | 313 | 111435 | 67215 | 50426161 |
Product dose omission issue | 68.17 | 10.27 | 195 | 111553 | 183643 | 50309733 |
Abortion induced | 67.69 | 10.27 | 93 | 111655 | 9251 | 50484125 |
Lethargy | 67.25 | 10.27 | 251 | 111497 | 49181 | 50444195 |
Enuresis | 65.92 | 10.27 | 47 | 111701 | 2082 | 50491294 |
Gingival hypertrophy | 65.88 | 10.27 | 40 | 111708 | 1346 | 50492030 |
Stillbirth | 65.32 | 10.27 | 73 | 111675 | 5879 | 50487497 |
Death | 65.07 | 10.27 | 436 | 111312 | 324943 | 50168433 |
Atrial septal defect | 64.89 | 10.27 | 75 | 111673 | 6266 | 50487110 |
Neurodevelopmental disorder | 64.72 | 10.27 | 14 | 111734 | 9 | 50493367 |
Oculogyric crisis | 64.54 | 10.27 | 40 | 111708 | 1397 | 50491979 |
Congenital eyelid malformation | 63.84 | 10.27 | 13 | 111735 | 3 | 50493373 |
Drug level below therapeutic | 63.32 | 10.27 | 58 | 111690 | 3682 | 50489694 |
Infantile spasms | 63.17 | 10.27 | 22 | 111726 | 190 | 50493186 |
Ileus paralytic | 63.16 | 10.27 | 60 | 111688 | 3990 | 50489386 |
Hyperlactacidaemia | 62.50 | 10.27 | 48 | 111700 | 2385 | 50490991 |
Weight increased | 62.38 | 10.27 | 701 | 111047 | 201190 | 50292186 |
Blood prolactin increased | 62.35 | 10.27 | 53 | 111695 | 3046 | 50490330 |
Dyspraxia | 62.20 | 10.27 | 23 | 111725 | 240 | 50493136 |
Myocarditis | 61.99 | 10.27 | 82 | 111666 | 7865 | 50485511 |
Metabolic encephalopathy | 61.75 | 10.27 | 66 | 111682 | 5055 | 50488321 |
Hepatic function abnormal | 61.38 | 10.27 | 185 | 111563 | 32496 | 50460880 |
Toxic encephalopathy | 61.14 | 10.27 | 68 | 111680 | 5447 | 50487929 |
Dystonia | 61.13 | 10.27 | 101 | 111647 | 11825 | 50481551 |
Blood pressure increased | 60.52 | 10.27 | 127 | 111621 | 133005 | 50360371 |
Influenza | 60.49 | 10.27 | 65 | 111683 | 89473 | 50403903 |
Attention deficit hyperactivity disorder | 60.38 | 10.27 | 47 | 111701 | 2382 | 50490994 |
Malignant neoplasm progression | 60.21 | 10.27 | 38 | 111710 | 68086 | 50425290 |
Acidosis hyperchloraemic | 60.04 | 10.27 | 24 | 111724 | 314 | 50493062 |
Brain oedema | 59.73 | 10.27 | 102 | 111646 | 12268 | 50481108 |
Restlessness | 59.58 | 10.27 | 155 | 111593 | 25018 | 50468358 |
Resting tremor | 59.48 | 10.27 | 30 | 111718 | 696 | 50492680 |
Dementia | 58.47 | 10.27 | 117 | 111631 | 15880 | 50477496 |
Seizure cluster | 58.40 | 10.27 | 21 | 111727 | 201 | 50493175 |
Gastrointestinal disorder | 57.98 | 10.27 | 74 | 111674 | 94382 | 50398994 |
Psoriatic arthropathy | 57.97 | 10.27 | 16 | 111732 | 47016 | 50446360 |
Knee arthroplasty | 57.70 | 10.27 | 6 | 111742 | 35840 | 50457536 |
Paranoia | 57.62 | 10.27 | 91 | 111657 | 10257 | 50483119 |
Dyspnoea exertional | 56.81 | 10.27 | 21 | 111727 | 51212 | 50442164 |
Plasma cell myeloma | 56.77 | 10.27 | 3 | 111745 | 31319 | 50462057 |
Poisoning | 56.76 | 10.27 | 100 | 111648 | 12329 | 50481047 |
Communication disorder | 56.75 | 10.27 | 44 | 111704 | 2217 | 50491159 |
Nasal congestion | 56.60 | 10.27 | 21 | 111727 | 51099 | 50442277 |
Mitochondrial DNA mutation | 55.97 | 10.27 | 21 | 111727 | 229 | 50493147 |
Flushing | 55.71 | 10.27 | 40 | 111708 | 66975 | 50426401 |
Personal relationship issue | 55.68 | 10.27 | 14 | 111734 | 30 | 50493346 |
Gastrointestinal haemorrhage | 55.61 | 10.27 | 48 | 111700 | 73273 | 50420103 |
Suicidal behaviour | 55.52 | 10.27 | 44 | 111704 | 2290 | 50491086 |
Neovascularisation | 55.38 | 10.27 | 32 | 111716 | 981 | 50492395 |
Hypoaesthesia | 54.86 | 10.27 | 125 | 111623 | 127132 | 50366244 |
Injection site reaction | 54.65 | 10.27 | 21 | 111727 | 50011 | 50443365 |
Astigmatism | 53.66 | 10.27 | 31 | 111717 | 950 | 50492426 |
Atrial fibrillation | 53.34 | 10.27 | 89 | 111659 | 101656 | 50391720 |
Injection site pruritus | 53.19 | 10.27 | 12 | 111736 | 40399 | 50452977 |
Grandiosity | 53.15 | 10.27 | 21 | 111727 | 266 | 50493110 |
Productive cough | 52.95 | 10.27 | 25 | 111723 | 52669 | 50440707 |
Fluid retention | 52.50 | 10.27 | 23 | 111725 | 50626 | 50442750 |
Tonic clonic movements | 51.96 | 10.27 | 33 | 111715 | 1204 | 50492172 |
Mental status changes | 51.70 | 10.27 | 187 | 111561 | 36085 | 50457291 |
Anger | 51.52 | 10.27 | 91 | 111657 | 11242 | 50482134 |
Encephalitis autoimmune | 51.45 | 10.27 | 33 | 111715 | 1225 | 50492151 |
Myalgia | 51.28 | 10.27 | 125 | 111623 | 124194 | 50369182 |
Intra-abdominal pressure increased | 51.23 | 10.27 | 19 | 111729 | 200 | 50493176 |
Rhinorrhoea | 51.03 | 10.27 | 25 | 111723 | 51558 | 50441818 |
Bipolar I disorder | 50.46 | 10.27 | 35 | 111713 | 1483 | 50491893 |
Hypokinesia | 50.34 | 10.27 | 94 | 111654 | 12123 | 50481253 |
Injection site swelling | 50.03 | 10.27 | 15 | 111733 | 41758 | 50451618 |
Hepatic failure | 49.95 | 10.27 | 171 | 111577 | 32112 | 50461264 |
Bone pain | 49.67 | 10.27 | 21 | 111727 | 47208 | 50446168 |
Dyslexia | 49.54 | 10.27 | 20 | 111728 | 269 | 50493107 |
Thrombosis | 49.53 | 10.27 | 31 | 111717 | 55802 | 50437574 |
Hypertonia | 49.32 | 10.27 | 52 | 111696 | 3921 | 50489455 |
Drug hypersensitivity | 49.31 | 10.27 | 338 | 111410 | 250672 | 50242704 |
Irritable bowel syndrome | 49.29 | 10.27 | 26 | 111722 | 51415 | 50441961 |
Hallucination | 49.23 | 10.27 | 219 | 111529 | 46438 | 50446938 |
Musculoskeletal pain | 49.19 | 10.27 | 52 | 111696 | 72125 | 50421251 |
Lower respiratory tract infection | 48.33 | 10.27 | 85 | 111663 | 95116 | 50398260 |
Dysgraphia | 48.30 | 10.27 | 43 | 111705 | 2630 | 50490746 |
Myopia | 48.23 | 10.27 | 34 | 111714 | 1479 | 50491897 |
Wheezing | 47.81 | 10.27 | 40 | 111708 | 62007 | 50431369 |
Lip disorder | 47.50 | 10.27 | 31 | 111717 | 1186 | 50492190 |
Depressed mood | 47.30 | 10.27 | 174 | 111574 | 33849 | 50459527 |
Cerebellar atrophy | 47.27 | 10.27 | 25 | 111723 | 642 | 50492734 |
Lordosis | 46.90 | 10.27 | 19 | 111729 | 258 | 50493118 |
Selective eating disorder | 46.74 | 10.27 | 36 | 111712 | 1796 | 50491580 |
Psoriasis | 46.70 | 10.27 | 50 | 111698 | 68950 | 50424426 |
Disease progression | 46.52 | 10.27 | 88 | 111660 | 95778 | 50397598 |
Abdominal pain | 46.44 | 10.27 | 318 | 111430 | 235910 | 50257466 |
Amenorrhoea | 46.40 | 10.27 | 74 | 111674 | 8410 | 50484966 |
Differential white blood cell count abnormal | 46.17 | 10.27 | 25 | 111723 | 674 | 50492702 |
Congenital scoliosis | 45.89 | 10.27 | 10 | 111738 | 7 | 50493369 |
Angiofibroma | 45.69 | 10.27 | 15 | 111733 | 106 | 50493270 |
Ventricular septal defect | 45.10 | 10.27 | 50 | 111698 | 3991 | 50489385 |
Inflammation | 44.71 | 10.27 | 36 | 111712 | 56876 | 50436500 |
Antipsychotic drug level decreased | 44.38 | 10.27 | 17 | 111731 | 197 | 50493179 |
Bradykinesia | 44.37 | 10.27 | 49 | 111699 | 3894 | 50489482 |
White blood cell count increased | 44.36 | 10.27 | 198 | 111550 | 42042 | 50451334 |
Bronchitis | 44.33 | 10.27 | 103 | 111645 | 104056 | 50389320 |
Clinodactyly | 44.18 | 10.27 | 14 | 111734 | 87 | 50493289 |
Blood pressure systolic increased | 43.80 | 10.27 | 12 | 111736 | 35437 | 50457939 |
Hepatic enzyme increased | 43.71 | 10.27 | 156 | 111592 | 137224 | 50356152 |
Chest discomfort | 43.35 | 10.27 | 87 | 111661 | 92635 | 50400741 |
Asthenia | 43.31 | 10.27 | 473 | 111275 | 318569 | 50174807 |
Reflexes abnormal | 43.06 | 10.27 | 22 | 111726 | 525 | 50492851 |
Hyponatraemia | 43.05 | 10.27 | 361 | 111387 | 95778 | 50397598 |
Limbic encephalitis | 42.98 | 10.27 | 17 | 111731 | 216 | 50493160 |
Coordination abnormal | 42.92 | 10.27 | 85 | 111663 | 11449 | 50481927 |
Dysmetria | 42.86 | 10.27 | 20 | 111728 | 389 | 50492987 |
Hallucinations, mixed | 42.78 | 10.27 | 49 | 111699 | 4054 | 50489322 |
Hypertension | 42.66 | 10.27 | 282 | 111466 | 210921 | 50282455 |
COVID-19 | 42.66 | 10.27 | 25 | 111723 | 46637 | 50446739 |
Chills | 42.46 | 10.27 | 94 | 111654 | 96593 | 50396783 |
Contusion | 42.29 | 10.27 | 118 | 111630 | 112065 | 50381311 |
Arachnodactyly | 41.98 | 10.27 | 13 | 111735 | 74 | 50493302 |
Pneumatosis | 41.86 | 10.27 | 20 | 111728 | 411 | 50492965 |
Drop attacks | 41.85 | 10.27 | 23 | 111725 | 639 | 50492737 |
Aphasia | 41.54 | 10.27 | 148 | 111600 | 28346 | 50465030 |
Tooth malformation | 41.48 | 10.27 | 9 | 111739 | 6 | 50493370 |
C-reactive protein abnormal | 41.47 | 10.27 | 6 | 111742 | 27803 | 50465573 |
Hot flush | 41.33 | 10.27 | 23 | 111725 | 44146 | 50449230 |
Antipsychotic drug level above therapeutic | 41.32 | 10.27 | 26 | 111722 | 933 | 50492443 |
Logorrhoea | 41.23 | 10.27 | 37 | 111711 | 2287 | 50491089 |
Dry skin | 41.13 | 10.27 | 22 | 111726 | 43169 | 50450207 |
Injection site bruising | 40.88 | 10.27 | 15 | 111733 | 36753 | 50456623 |
Asterixis | 40.86 | 10.27 | 28 | 111720 | 1163 | 50492213 |
Nephrogenic diabetes insipidus | 40.78 | 10.27 | 25 | 111723 | 856 | 50492520 |
Refusal of treatment by patient | 40.75 | 10.27 | 53 | 111695 | 5000 | 50488376 |
Pectus excavatum | 40.72 | 10.27 | 13 | 111735 | 83 | 50493293 |
Craniosynostosis | 40.61 | 10.27 | 15 | 111733 | 156 | 50493220 |
Pain in jaw | 40.55 | 10.27 | 17 | 111731 | 38411 | 50454965 |
Neutropenia | 40.45 | 10.27 | 502 | 111246 | 147463 | 50345913 |
Change in seizure presentation | 40.19 | 10.27 | 17 | 111731 | 259 | 50493117 |
Interstitial lung disease | 40.09 | 10.27 | 35 | 111713 | 53141 | 50440235 |
Eosinophilic pleural effusion | 39.73 | 10.27 | 11 | 111737 | 39 | 50493337 |
Mood swings | 39.58 | 10.27 | 100 | 111648 | 15854 | 50477522 |
Treatment failure | 39.47 | 10.27 | 163 | 111585 | 137474 | 50355902 |
Metabolic acidosis | 39.28 | 10.27 | 180 | 111568 | 38645 | 50454731 |
Psychotic behaviour | 39.26 | 10.27 | 21 | 111727 | 552 | 50492824 |
Retinogram abnormal | 39.21 | 10.27 | 14 | 111734 | 131 | 50493245 |
Hyperthermia | 39.20 | 10.27 | 65 | 111683 | 7631 | 50485745 |
Oral mucosa erosion | 39.05 | 10.27 | 26 | 111722 | 1029 | 50492347 |
Oropharyngeal pain | 39 | 10.27 | 70 | 111678 | 77731 | 50415645 |
Plagiocephaly | 38.89 | 10.27 | 11 | 111737 | 43 | 50493333 |
Acute hepatic failure | 38.61 | 10.27 | 98 | 111650 | 15579 | 50477797 |
Carnitine decreased | 38.40 | 10.27 | 8 | 111740 | 3 | 50493373 |
Cataract | 38.31 | 10.27 | 29 | 111719 | 47271 | 50446105 |
Sluggishness | 38.29 | 10.27 | 48 | 111700 | 4365 | 50489011 |
Hip arthroplasty | 38.16 | 10.27 | 10 | 111738 | 30419 | 50462957 |
Malaise | 38.11 | 10.27 | 517 | 111231 | 335015 | 50158361 |
Blood lactic acid increased | 38.08 | 10.27 | 54 | 111694 | 5531 | 50487845 |
Oropharyngeal oedema | 38.05 | 10.27 | 16 | 111732 | 240 | 50493136 |
Adjustment disorder with mixed anxiety and depressed mood | 37.94 | 10.27 | 12 | 111736 | 74 | 50493302 |
Hypersexuality | 37.90 | 10.27 | 19 | 111729 | 435 | 50492941 |
Necrosis ischaemic | 37.82 | 10.27 | 23 | 111725 | 776 | 50492600 |
Tachycardia | 37.68 | 10.27 | 361 | 111387 | 99402 | 50393974 |
Multiple congenital abnormalities | 37.48 | 10.27 | 20 | 111728 | 523 | 50492853 |
Neutrophil count increased | 37.35 | 10.27 | 91 | 111657 | 14104 | 50479272 |
Epistaxis | 37.31 | 10.27 | 52 | 111696 | 63902 | 50429474 |
Hallucination, visual | 37.10 | 10.27 | 100 | 111648 | 16482 | 50476894 |
Sinus rhythm | 37.09 | 10.27 | 21 | 111727 | 619 | 50492757 |
Muscle spasms | 37.06 | 10.27 | 147 | 111601 | 125406 | 50367970 |
Congenital anomaly | 36.88 | 10.27 | 29 | 111719 | 1492 | 50491884 |
Affective disorder | 36.67 | 10.27 | 51 | 111697 | 5130 | 50488246 |
Pneumonia | 36.13 | 10.27 | 603 | 111145 | 377798 | 50115578 |
Apathy | 36.12 | 10.27 | 62 | 111686 | 7486 | 50485890 |
Weight gain poor | 36.11 | 10.27 | 22 | 111726 | 745 | 50492631 |
Psychotic symptom | 35.79 | 10.27 | 26 | 111722 | 1186 | 50492190 |
Urinary incontinence | 35.70 | 10.27 | 140 | 111608 | 28068 | 50465308 |
Haematochezia | 35.57 | 10.27 | 22 | 111726 | 39860 | 50453516 |
Inappropriate antidiuretic hormone secretion | 35.38 | 10.27 | 85 | 111663 | 13058 | 50480318 |
Hyperchloraemia | 35.31 | 10.27 | 21 | 111727 | 680 | 50492696 |
Hypermetropia | 35.06 | 10.27 | 18 | 111730 | 434 | 50492942 |
Congenital joint malformation | 34.93 | 10.27 | 8 | 111740 | 9 | 50493367 |
Psychiatric decompensation | 34.93 | 10.27 | 26 | 111722 | 1232 | 50492144 |
Delusion of grandeur | 34.79 | 10.27 | 13 | 111735 | 140 | 50493236 |
Gene mutation | 34.69 | 10.27 | 26 | 111722 | 1245 | 50492131 |
Camptodactyly congenital | 34.48 | 10.27 | 8 | 111740 | 10 | 50493366 |
Platelet count decreased | 34.42 | 10.27 | 357 | 111391 | 100369 | 50393007 |
Partial seizures with secondary generalisation | 34.34 | 10.27 | 16 | 111732 | 310 | 50493066 |
Throat irritation | 34.19 | 10.27 | 12 | 111736 | 30227 | 50463149 |
Bradycardia neonatal | 34.12 | 10.27 | 22 | 111726 | 824 | 50492552 |
Balance disorder | 33.71 | 10.27 | 269 | 111479 | 70321 | 50423055 |
Porphyria acute | 33.45 | 10.27 | 18 | 111730 | 479 | 50492897 |
Poor sucking reflex | 33.42 | 10.27 | 14 | 111734 | 208 | 50493168 |
Hyperglycinaemia | 33.34 | 10.27 | 7 | 111741 | 3 | 50493373 |
Speech sound disorder | 33.34 | 10.27 | 7 | 111741 | 3 | 50493373 |
Mydriasis | 33.32 | 10.27 | 73 | 111675 | 10554 | 50482822 |
Unresponsive to stimuli | 33.29 | 10.27 | 145 | 111603 | 30464 | 50462912 |
Gait disturbance | 33.22 | 10.27 | 490 | 111258 | 149515 | 50343861 |
Galactorrhoea | 33.11 | 10.27 | 41 | 111707 | 3682 | 50489694 |
General physical health deterioration | 33.04 | 10.27 | 182 | 111566 | 142252 | 50351124 |
Metabolic disorder | 32.97 | 10.27 | 49 | 111699 | 5237 | 50488139 |
Brief psychotic disorder, with postpartum onset | 32.93 | 10.27 | 9 | 111739 | 30 | 50493346 |
Antipsychotic drug level below therapeutic | 32.80 | 10.27 | 15 | 111733 | 278 | 50493098 |
Conjunctival hyperaemia | 32.76 | 10.27 | 31 | 111717 | 2051 | 50491325 |
Posture abnormal | 32.67 | 10.27 | 31 | 111717 | 2058 | 50491318 |
Anaphylactic reaction | 32.49 | 10.27 | 43 | 111705 | 54012 | 50439364 |
Congenital hair disorder | 32.43 | 10.27 | 10 | 111738 | 56 | 50493320 |
Neoplasm progression | 32.24 | 10.27 | 12 | 111736 | 29145 | 50464231 |
High arched palate | 32.21 | 10.27 | 11 | 111737 | 89 | 50493287 |
Nipple disorder | 32.11 | 10.27 | 11 | 111737 | 90 | 50493286 |
Polydipsia | 32.05 | 10.27 | 37 | 111711 | 3087 | 50490289 |
Fungal infection | 32.03 | 10.27 | 13 | 111735 | 29952 | 50463424 |
Medication overuse headache | 31.93 | 10.27 | 19 | 111729 | 616 | 50492760 |
Leukocytosis | 31.83 | 10.27 | 116 | 111632 | 22463 | 50470913 |
Screaming | 31.78 | 10.27 | 36 | 111712 | 2942 | 50490434 |
Device expulsion | 31.64 | 10.27 | 12 | 111736 | 28810 | 50464566 |
Cystitis | 31.62 | 10.27 | 31 | 111717 | 44533 | 50448843 |
Reading disorder | 31.61 | 10.27 | 20 | 111728 | 725 | 50492651 |
Rabbit syndrome | 31.54 | 10.27 | 15 | 111733 | 305 | 50493071 |
Cleft palate | 31.53 | 10.27 | 22 | 111726 | 941 | 50492435 |
Diverticulitis | 31.45 | 10.27 | 17 | 111731 | 33165 | 50460211 |
Drug level above therapeutic | 31.43 | 10.27 | 41 | 111707 | 3879 | 50489497 |
Gaze palsy | 31.43 | 10.27 | 25 | 111723 | 1308 | 50492068 |
Depressive symptom | 31.33 | 10.27 | 37 | 111711 | 3163 | 50490213 |
Foetal death | 31.31 | 10.27 | 61 | 111687 | 8119 | 50485257 |
Anticonvulsant drug level abnormal | 31.27 | 10.27 | 9 | 111739 | 38 | 50493338 |
Glycosuria | 31.25 | 10.27 | 23 | 111725 | 1071 | 50492305 |
Tic | 31.24 | 10.27 | 24 | 111724 | 1193 | 50492183 |
Rash maculo-papular | 31.14 | 10.27 | 129 | 111619 | 26512 | 50466864 |
Localised infection | 30.79 | 10.27 | 9 | 111739 | 25476 | 50467900 |
Neck pain | 30.76 | 10.27 | 49 | 111699 | 57018 | 50436358 |
Congenital flat feet | 30.71 | 10.27 | 6 | 111742 | 0 | 50493376 |
Night sweats | 30.67 | 10.27 | 18 | 111730 | 33556 | 50459820 |
Obesity | 30.59 | 10.27 | 94 | 111654 | 16681 | 50476695 |
Breast hyperplasia | 30.59 | 10.27 | 14 | 111734 | 260 | 50493116 |
Renal tubular acidosis | 30.38 | 10.27 | 26 | 111722 | 1508 | 50491868 |
Palpitations | 30.26 | 10.27 | 107 | 111641 | 94399 | 50398977 |
Angiomyolipoma | 30.16 | 10.27 | 13 | 111735 | 208 | 50493168 |
Paraesthesia | 29.92 | 10.27 | 150 | 111598 | 120093 | 50373283 |
Hypophosphataemic osteomalacia | 29.88 | 10.27 | 12 | 111736 | 159 | 50493217 |
Myocardial infarction | 29.72 | 10.27 | 99 | 111649 | 88928 | 50404448 |
Motor dysfunction | 29.66 | 10.27 | 59 | 111689 | 7972 | 50485404 |
Respiratory disorder neonatal | 29.66 | 10.27 | 21 | 111727 | 920 | 50492456 |
Skin ulcer | 29.45 | 10.27 | 21 | 111727 | 35297 | 50458079 |
Ovarian granulosa-theca cell tumour | 29.43 | 10.27 | 8 | 111740 | 26 | 50493350 |
Cardiac failure | 29.38 | 10.27 | 79 | 111669 | 75961 | 50417415 |
Deafness congenital | 29.24 | 10.27 | 7 | 111741 | 11 | 50493365 |
Blister | 29.20 | 10.27 | 94 | 111654 | 85324 | 50408052 |
Automatism | 28.95 | 10.27 | 9 | 111739 | 52 | 50493324 |
Polydactyly | 28.90 | 10.27 | 14 | 111734 | 297 | 50493079 |
Fibromyalgia | 28.89 | 10.27 | 34 | 111714 | 44944 | 50448432 |
Akinesia | 28.86 | 10.27 | 25 | 111723 | 1474 | 50491902 |
Hypermobility syndrome | 28.86 | 10.27 | 19 | 111729 | 738 | 50492638 |
Subileus | 28.85 | 10.27 | 33 | 111715 | 2726 | 50490650 |
Prognathism | 28.75 | 10.27 | 10 | 111738 | 86 | 50493290 |
Strabismus congenital | 28.67 | 10.27 | 9 | 111739 | 54 | 50493322 |
Mucosal inflammation | 28.39 | 10.27 | 28 | 111720 | 40114 | 50453262 |
Congenital oral malformation | 28.36 | 10.27 | 12 | 111736 | 183 | 50493193 |
Drooling | 28.08 | 10.27 | 36 | 111712 | 3348 | 50490028 |
Verbal abuse | 28.06 | 10.27 | 10 | 111738 | 93 | 50493283 |
Congenital central nervous system anomaly | 27.99 | 10.27 | 14 | 111734 | 319 | 50493057 |
Dyscalculia | 27.87 | 10.27 | 10 | 111738 | 95 | 50493281 |
Hepatotoxicity | 27.37 | 10.27 | 126 | 111622 | 27100 | 50466276 |
Accidental overdose | 27.24 | 10.27 | 100 | 111648 | 19433 | 50473943 |
Pulmonary fibrosis | 27.11 | 10.27 | 10 | 111738 | 24427 | 50468949 |
Cogwheel rigidity | 27.09 | 10.27 | 26 | 111722 | 1751 | 50491625 |
Pancreatitis necrotising | 26.93 | 10.27 | 23 | 111725 | 1330 | 50492046 |
Constipation | 26.91 | 10.27 | 271 | 111477 | 185437 | 50307939 |
Weight decreased | 26.88 | 10.27 | 336 | 111412 | 220909 | 50272467 |
Respiratory acidosis | 26.88 | 10.27 | 48 | 111700 | 5980 | 50487396 |
Eye movement disorder | 26.74 | 10.27 | 41 | 111707 | 4504 | 50488872 |
Blood gases abnormal | 26.72 | 10.27 | 17 | 111731 | 622 | 50492754 |
Joint stiffness | 26.64 | 10.27 | 17 | 111731 | 30291 | 50463085 |
Mood altered | 26.56 | 10.27 | 75 | 111673 | 12698 | 50480678 |
Metastases to bone | 26.56 | 10.27 | 4 | 111744 | 17991 | 50475385 |
Impaired reasoning | 26.55 | 10.27 | 9 | 111739 | 71 | 50493305 |
Diplopia | 26.35 | 10.27 | 98 | 111650 | 19162 | 50474214 |
Apraxia | 26.23 | 10.27 | 24 | 111724 | 1521 | 50491855 |
Hirsutism | 26.23 | 10.27 | 20 | 111728 | 983 | 50492393 |
Dacryostenosis congenital | 26.08 | 10.27 | 6 | 111742 | 7 | 50493369 |
Monocytosis | 25.84 | 10.27 | 13 | 111735 | 300 | 50493076 |
Echolalia | 25.75 | 10.27 | 11 | 111737 | 172 | 50493204 |
Physical assault | 25.73 | 10.27 | 19 | 111729 | 889 | 50492487 |
Heterophoria | 25.69 | 10.27 | 7 | 111741 | 23 | 50493353 |
Disinhibition | 25.35 | 10.27 | 18 | 111730 | 792 | 50492584 |
Withdrawal syndrome | 25.33 | 10.27 | 91 | 111657 | 17499 | 50475877 |
Staring | 25.23 | 10.27 | 23 | 111725 | 1451 | 50491925 |
Social avoidant behaviour | 25.19 | 10.27 | 31 | 111717 | 2766 | 50490610 |
Product use issue | 25.18 | 10.27 | 210 | 111538 | 149265 | 50344111 |
Osteonecrosis of jaw | 25.01 | 10.27 | 21 | 111727 | 32505 | 50460871 |
Lactate pyruvate ratio increased | 24.95 | 10.27 | 9 | 111739 | 87 | 50493289 |
Ultrasound ovary abnormal | 24.95 | 10.27 | 9 | 111739 | 87 | 50493289 |
Ill-defined disorder | 24.93 | 10.27 | 52 | 111696 | 54602 | 50438774 |
Cellulitis | 24.83 | 10.27 | 77 | 111671 | 70721 | 50422655 |
Urinary tract infection | 24.74 | 10.27 | 347 | 111401 | 223673 | 50269703 |
Pancreatitis | 24.67 | 10.27 | 170 | 111578 | 42444 | 50450932 |
Ear disorder | 24.58 | 10.27 | 33 | 111715 | 3210 | 50490166 |
Erythema | 24.52 | 10.27 | 206 | 111542 | 146208 | 50347168 |
Palmar-plantar erythrodysaesthesia syndrome | 24.46 | 10.27 | 7 | 111741 | 20091 | 50473285 |
Illogical thinking | 24.31 | 10.27 | 8 | 111740 | 57 | 50493319 |
Hypervolaemia | 24.26 | 10.27 | 13 | 111735 | 25486 | 50467890 |
Hypotonia neonatal | 24.15 | 10.27 | 19 | 111729 | 978 | 50492398 |
Congenital cystic kidney disease | 24.12 | 10.27 | 13 | 111735 | 347 | 50493029 |
Rotavirus infection | 24.09 | 10.27 | 12 | 111736 | 271 | 50493105 |
Heart rate decreased | 24.08 | 10.27 | 27 | 111721 | 36470 | 50456906 |
Hereditary ataxia | 24.05 | 10.27 | 7 | 111741 | 31 | 50493345 |
Cerebellar syndrome | 24.05 | 10.27 | 33 | 111715 | 3278 | 50490098 |
Pneumonitis | 24.02 | 10.27 | 18 | 111730 | 29492 | 50463884 |
Loss of personal independence in daily activities | 24.00 | 10.27 | 77 | 111671 | 69973 | 50423403 |
Precocious puberty | 24.00 | 10.27 | 11 | 111737 | 205 | 50493171 |
Pulmonary hypertension | 23.99 | 10.27 | 23 | 111725 | 33394 | 50459982 |
Vestibular migraine | 23.95 | 10.27 | 11 | 111737 | 206 | 50493170 |
Eosinophilia | 23.94 | 10.27 | 93 | 111655 | 18559 | 50474817 |
Depression | 23.93 | 10.27 | 505 | 111243 | 164918 | 50328458 |
Obsessive-compulsive disorder | 23.82 | 10.27 | 33 | 111715 | 3307 | 50490069 |
Feeling hot | 23.75 | 10.27 | 31 | 111717 | 39171 | 50454205 |
Upper respiratory tract infection | 23.59 | 10.27 | 71 | 111677 | 65827 | 50427549 |
Basal cell carcinoma | 23.59 | 10.27 | 11 | 111737 | 23345 | 50470031 |
Executive dysfunction | 23.55 | 10.27 | 10 | 111738 | 154 | 50493222 |
Lymphangioleiomyomatosis | 23.43 | 10.27 | 10 | 111738 | 156 | 50493220 |
Stereotypy | 23.40 | 10.27 | 13 | 111735 | 369 | 50493007 |
Intentional product misuse | 23.36 | 10.27 | 180 | 111568 | 46554 | 50446822 |
Borderline personality disorder | 23.19 | 10.27 | 16 | 111732 | 672 | 50492704 |
Polycystic ovaries | 23.13 | 10.27 | 28 | 111720 | 2456 | 50490920 |
Nasal disorder | 23.12 | 10.27 | 27 | 111721 | 2281 | 50491095 |
Mitochondrial cytopathy | 23.11 | 10.27 | 11 | 111737 | 224 | 50493152 |
Bursitis | 23.02 | 10.27 | 10 | 111738 | 22125 | 50471251 |
Cerebral ventricle dilatation | 23.01 | 10.27 | 18 | 111730 | 919 | 50492457 |
Injection site rash | 22.97 | 10.27 | 4 | 111744 | 16173 | 50477203 |
Miosis | 22.88 | 10.27 | 46 | 111702 | 6264 | 50487112 |
Growth retardation | 22.85 | 10.27 | 19 | 111729 | 1059 | 50492317 |
Drug eruption | 22.81 | 10.27 | 108 | 111640 | 23498 | 50469878 |
Hypothyroidism | 22.72 | 10.27 | 141 | 111607 | 33984 | 50459392 |
Surgery | 22.62 | 10.27 | 20 | 111728 | 30185 | 50463191 |
Red blood cell sedimentation rate increased | 22.61 | 10.27 | 19 | 111729 | 29397 | 50463979 |
Mutism | 22.57 | 10.27 | 21 | 111727 | 1360 | 50492016 |
Conductive deafness | 22.49 | 10.27 | 8 | 111740 | 74 | 50493302 |
Asthma | 22.48 | 10.27 | 111 | 111637 | 89226 | 50404150 |
Anaemia macrocytic | 22.46 | 10.27 | 28 | 111720 | 2531 | 50490845 |
Right ventricular failure | 22.41 | 10.27 | 4 | 111744 | 15889 | 50477487 |
Product use in unapproved indication | 22.08 | 10.27 | 369 | 111379 | 115450 | 50377926 |
Conversion disorder | 21.82 | 10.27 | 22 | 111726 | 1574 | 50491802 |
Illiteracy | 21.73 | 10.27 | 6 | 111742 | 21 | 50493355 |
Macular degeneration | 21.70 | 10.27 | 3 | 111745 | 14385 | 50478991 |
Injection site haemorrhage | 21.64 | 10.27 | 10 | 111738 | 21336 | 50472040 |
Pancreatitis acute | 21.61 | 10.27 | 107 | 111641 | 23705 | 50469671 |
Influenza B virus test positive | 21.59 | 10.27 | 11 | 111737 | 261 | 50493115 |
Therapeutic product effective for unapproved indication | 21.42 | 10.27 | 8 | 111740 | 86 | 50493290 |
Pulmonary arterial hypertension | 21.42 | 10.27 | 9 | 111739 | 20310 | 50473066 |
Right ventricular hypertrophy | 21.39 | 10.27 | 15 | 111733 | 647 | 50492729 |
Dysgeusia | 21.36 | 10.27 | 33 | 111715 | 38883 | 50454493 |
Ulcer | 21.21 | 10.27 | 9 | 111739 | 20191 | 50473185 |
Breast cancer | 21.12 | 10.27 | 39 | 111709 | 42851 | 50450525 |
Metabolic syndrome | 21.09 | 10.27 | 20 | 111728 | 1327 | 50492049 |
Osteoporosis | 21.06 | 10.27 | 42 | 111706 | 44837 | 50448539 |
Negativism | 21.06 | 10.27 | 12 | 111736 | 358 | 50493018 |
Metastases to liver | 21.04 | 10.27 | 9 | 111739 | 20095 | 50473281 |
Urine amphetamine positive | 21.02 | 10.27 | 7 | 111741 | 52 | 50493324 |
Neglect of personal appearance | 21.02 | 10.27 | 8 | 111740 | 91 | 50493285 |
Blood pressure fluctuation | 21.02 | 10.27 | 29 | 111719 | 35794 | 50457582 |
Developmental regression | 20.91 | 10.27 | 6 | 111742 | 25 | 50493351 |
Mobility decreased | 20.89 | 10.27 | 98 | 111650 | 79850 | 50413526 |
Drug withdrawal syndrome | 20.88 | 10.27 | 110 | 111638 | 24971 | 50468405 |
Sinus congestion | 20.86 | 10.27 | 3 | 111745 | 13968 | 50479408 |
Cleft uvula | 20.83 | 10.27 | 5 | 111743 | 8 | 50493368 |
Memory impairment | 20.71 | 10.27 | 267 | 111481 | 79093 | 50414283 |
Agranulocytosis | 20.70 | 10.27 | 98 | 111650 | 21323 | 50472053 |
Drug screen false positive | 20.69 | 10.27 | 16 | 111732 | 803 | 50492573 |
Brain death | 20.61 | 10.27 | 28 | 111720 | 2755 | 50490621 |
Intelligence test abnormal | 20.47 | 10.27 | 4 | 111744 | 0 | 50493376 |
Optic nerve hypoplasia | 20.47 | 10.27 | 4 | 111744 | 0 | 50493376 |
Anomaly of orbit, congenital | 20.47 | 10.27 | 4 | 111744 | 0 | 50493376 |
Gaucher's disease | 20.47 | 10.27 | 4 | 111744 | 0 | 50493376 |
Full blood count decreased | 20.38 | 10.27 | 12 | 111736 | 22334 | 50471042 |
Gastrooesophageal reflux disease | 20.37 | 10.27 | 93 | 111655 | 76335 | 50417041 |
Retinitis pigmentosa | 20.34 | 10.27 | 8 | 111740 | 100 | 50493276 |
Flatulence | 20.32 | 10.27 | 21 | 111727 | 29437 | 50463939 |
Increased appetite | 20.31 | 10.27 | 52 | 111696 | 8309 | 50485067 |
Kidney infection | 20.25 | 10.27 | 8 | 111740 | 18738 | 50474638 |
Acute generalised exanthematous pustulosis | 20.09 | 10.27 | 54 | 111694 | 8884 | 50484492 |
Reduced facial expression | 20.03 | 10.27 | 21 | 111727 | 1573 | 50491803 |
Mitochondrial enzyme deficiency | 20.02 | 10.27 | 6 | 111742 | 30 | 50493346 |
Acute kidney injury | 19.93 | 10.27 | 369 | 111379 | 227689 | 50265687 |
Sexually inappropriate behaviour | 19.92 | 10.27 | 8 | 111740 | 106 | 50493270 |
Neoplasm malignant | 19.91 | 10.27 | 14 | 111734 | 23701 | 50469675 |
Hepatic cirrhosis | 19.83 | 10.27 | 7 | 111741 | 17570 | 50475806 |
Cerebrovascular accident | 19.81 | 10.27 | 125 | 111623 | 94555 | 50398821 |
Thinking abnormal | 19.72 | 10.27 | 56 | 111692 | 9511 | 50483865 |
Acquired macroglossia | 19.67 | 10.27 | 9 | 111739 | 167 | 50493209 |
Cross sensitivity reaction | 19.66 | 10.27 | 23 | 111725 | 1946 | 50491430 |
Macroglossia | 19.56 | 10.27 | 14 | 111734 | 624 | 50492752 |
Cardiac steatosis | 19.55 | 10.27 | 6 | 111742 | 33 | 50493343 |
Hiatus hernia | 19.54 | 10.27 | 8 | 111740 | 18336 | 50475040 |
Knee deformity | 19.51 | 10.27 | 17 | 111731 | 1010 | 50492366 |
Oral pain | 19.45 | 10.27 | 16 | 111732 | 25017 | 50468359 |
Food interaction | 19.21 | 10.27 | 14 | 111734 | 642 | 50492734 |
Perseveration | 19.04 | 10.27 | 10 | 111738 | 253 | 50493123 |
Euphoric mood | 19.00 | 10.27 | 33 | 111715 | 4022 | 50489354 |
Attention-seeking behaviour | 18.93 | 10.27 | 7 | 111741 | 73 | 50493303 |
Transient aphasia | 18.84 | 10.27 | 6 | 111742 | 38 | 50493338 |
Sciatica | 18.78 | 10.27 | 12 | 111736 | 21370 | 50472006 |
Brachydactyly | 18.77 | 10.27 | 7 | 111741 | 75 | 50493301 |
Inappropriate affect | 18.74 | 10.27 | 15 | 111733 | 792 | 50492584 |
Congenital hepatomegaly | 18.69 | 10.27 | 5 | 111743 | 15 | 50493361 |
Hypoplastic left heart syndrome | 18.62 | 10.27 | 9 | 111739 | 190 | 50493186 |
Epileptic encephalopathy | 18.59 | 10.27 | 10 | 111738 | 266 | 50493110 |
Lennox-Gastaut syndrome | 18.55 | 10.27 | 10 | 111738 | 267 | 50493109 |
Lipids | 18.45 | 10.27 | 5 | 111743 | 16 | 50493360 |
Congenital hearing disorder | 18.45 | 10.27 | 5 | 111743 | 16 | 50493360 |
Hip fracture | 18.44 | 10.27 | 18 | 111730 | 25913 | 50467463 |
Limb discomfort | 18.39 | 10.27 | 16 | 111732 | 24341 | 50469035 |
Blood insulin increased | 18.39 | 10.27 | 8 | 111740 | 131 | 50493245 |
Head titubation | 18.34 | 10.27 | 14 | 111734 | 689 | 50492687 |
Clonus | 18.30 | 10.27 | 33 | 111715 | 4142 | 50489234 |
Nephrocalcinosis | 18.26 | 10.27 | 16 | 111732 | 958 | 50492418 |
Microstomia | 18.24 | 10.27 | 4 | 111744 | 3 | 50493373 |
School refusal | 18.24 | 10.27 | 4 | 111744 | 3 | 50493373 |
Ascites | 18.20 | 10.27 | 32 | 111716 | 35829 | 50457547 |
Full blood count abnormal | 18.11 | 10.27 | 15 | 111733 | 23373 | 50470003 |
Pneumocystis jirovecii pneumonia | 18.04 | 10.27 | 5 | 111743 | 14658 | 50478718 |
Urine sodium increased | 17.98 | 10.27 | 7 | 111741 | 85 | 50493291 |
Lipid metabolism disorder | 17.97 | 10.27 | 6 | 111742 | 45 | 50493331 |
Aspiration | 17.92 | 10.27 | 53 | 111695 | 9211 | 50484165 |
Haemoptysis | 17.90 | 10.27 | 18 | 111730 | 25555 | 50467821 |
Oral herpes | 17.71 | 10.27 | 12 | 111736 | 20713 | 50472663 |
Clostridium difficile infection | 17.70 | 10.27 | 18 | 111730 | 25421 | 50467955 |
Microphthalmos | 17.61 | 10.27 | 8 | 111740 | 146 | 50493230 |
Illness | 17.49 | 10.27 | 17 | 111731 | 24523 | 50468853 |
Plasmodium falciparum infection | 17.39 | 10.27 | 5 | 111743 | 21 | 50493355 |
Osmolar gap increased | 17.39 | 10.27 | 5 | 111743 | 21 | 50493355 |
Rectal haemorrhage | 17.32 | 10.27 | 37 | 111711 | 38521 | 50454855 |
Prominent epicanthal folds | 17.21 | 10.27 | 6 | 111742 | 52 | 50493324 |
False positive investigation result | 17.21 | 10.27 | 12 | 111736 | 513 | 50492863 |
Monocyte count decreased | 17.14 | 10.27 | 21 | 111727 | 1865 | 50491511 |
Pulmonary mass | 17.13 | 10.27 | 10 | 111738 | 18695 | 50474681 |
Bladder sphincter atony | 17.08 | 10.27 | 8 | 111740 | 157 | 50493219 |
Tooth infection | 17.02 | 10.27 | 5 | 111743 | 14107 | 50479269 |
Acute myeloid leukaemia | 17.01 | 10.27 | 6 | 111742 | 15068 | 50478308 |
Hypersomnia | 17.00 | 10.27 | 73 | 111675 | 15241 | 50478135 |
Ligament laxity | 16.99 | 10.27 | 8 | 111740 | 159 | 50493217 |
Micrognathia | 16.98 | 10.27 | 9 | 111739 | 232 | 50493144 |
Opisthotonus | 16.95 | 10.27 | 10 | 111738 | 319 | 50493057 |
Dehydration | 16.86 | 10.27 | 236 | 111512 | 152213 | 50341163 |
VIth nerve paralysis | 16.86 | 10.27 | 14 | 111734 | 779 | 50492597 |
Spina bifida occulta | 16.82 | 10.27 | 4 | 111744 | 6 | 50493370 |
Benign congenital hypotonia | 16.82 | 10.27 | 6 | 111742 | 56 | 50493320 |
Drug level changed | 16.81 | 10.27 | 8 | 111740 | 163 | 50493213 |
Vomiting | 16.80 | 10.27 | 839 | 110909 | 459919 | 50033457 |
Laryngeal stenosis | 16.79 | 10.27 | 14 | 111734 | 783 | 50492593 |
Creatinine renal clearance decreased | 16.73 | 10.27 | 3 | 111745 | 11878 | 50481498 |
Tachyphrenia | 16.72 | 10.27 | 17 | 111731 | 1228 | 50492148 |
Musculoskeletal discomfort | 16.69 | 10.27 | 6 | 111742 | 14892 | 50478484 |
Tendonitis | 16.67 | 10.27 | 8 | 111740 | 16697 | 50476679 |
Transfusion | 16.65 | 10.27 | 4 | 111744 | 12901 | 50480475 |
Parkinsonian gait | 16.62 | 10.27 | 11 | 111737 | 431 | 50492945 |
Renal failure | 16.54 | 10.27 | 153 | 111595 | 106480 | 50386896 |
Device issue | 16.49 | 10.27 | 12 | 111736 | 19960 | 50473416 |
Anotia | 16.44 | 10.27 | 4 | 111744 | 7 | 50493369 |
Incontinence | 16.42 | 10.27 | 54 | 111694 | 9931 | 50483445 |
Schizoaffective disorder bipolar type | 16.41 | 10.27 | 7 | 111741 | 109 | 50493267 |
Lip erosion | 16.39 | 10.27 | 14 | 111734 | 810 | 50492566 |
Dysphoria | 16.36 | 10.27 | 34 | 111714 | 4740 | 50488636 |
Bipolar II disorder | 16.34 | 10.27 | 9 | 111739 | 251 | 50493125 |
Renal hypoplasia | 16.22 | 10.27 | 5 | 111743 | 28 | 50493348 |
Urine calcium/creatinine ratio increased | 16.18 | 10.27 | 7 | 111741 | 113 | 50493263 |
Shock | 16.13 | 10.27 | 89 | 111659 | 20561 | 50472815 |
Ketosis-prone diabetes mellitus | 16.09 | 10.27 | 4 | 111744 | 8 | 50493368 |
Pancreatic injury | 16.07 | 10.27 | 5 | 111743 | 29 | 50493347 |
Lipids abnormal | 15.90 | 10.27 | 9 | 111739 | 265 | 50493111 |
Prothrombin time shortened | 15.87 | 10.27 | 19 | 111729 | 1648 | 50491728 |
Self-injurious ideation | 15.86 | 10.27 | 22 | 111726 | 2207 | 50491169 |
Bacteraemia | 15.86 | 10.27 | 6 | 111742 | 14427 | 50478949 |
Blood triglycerides increased | 15.84 | 10.27 | 58 | 111690 | 11254 | 50482122 |
Megakaryocytes abnormal | 15.79 | 10.27 | 5 | 111743 | 31 | 50493345 |
Electrocardiogram J wave abnormal | 15.78 | 10.27 | 4 | 111744 | 9 | 50493367 |
Head circumference abnormal | 15.78 | 10.27 | 4 | 111744 | 9 | 50493367 |
Eye pain | 15.74 | 10.27 | 24 | 111724 | 28425 | 50464951 |
Chorea | 15.68 | 10.27 | 17 | 111731 | 1323 | 50492053 |
Faeces discoloured | 15.67 | 10.27 | 8 | 111740 | 16116 | 50477260 |
Saccadic eye movement | 15.63 | 10.27 | 6 | 111742 | 70 | 50493306 |
Cardiac disorder | 15.60 | 10.27 | 46 | 111702 | 42933 | 50450443 |
Infusion site pain | 15.59 | 10.27 | 4 | 111744 | 12342 | 50481034 |
Asphyxia | 15.58 | 10.27 | 36 | 111712 | 5391 | 50487985 |
Coronary artery disease | 15.57 | 10.27 | 26 | 111722 | 29700 | 50463676 |
Serositis | 15.56 | 10.27 | 12 | 111736 | 600 | 50492776 |
Dysphagia | 15.52 | 10.27 | 249 | 111499 | 77269 | 50416107 |
Hyperphagia | 15.47 | 10.27 | 18 | 111730 | 1514 | 50491862 |
Drug level fluctuating | 15.45 | 10.27 | 10 | 111738 | 377 | 50492999 |
Joint range of motion decreased | 15.44 | 10.27 | 11 | 111737 | 18501 | 50474875 |
Vascular encephalopathy | 15.38 | 10.27 | 10 | 111738 | 380 | 50492996 |
Intestinal ischaemia | 15.37 | 10.27 | 41 | 111707 | 6716 | 50486660 |
Sinus disorder | 15.36 | 10.27 | 11 | 111737 | 18447 | 50474929 |
Congenital myopia | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Cognitive linguistic deficit | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Alpers disease | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
3-hydroxyacetyl-coenzyme A dehydrogenase deficiency | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Rhinotracheitis | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Social (pragmatic) communication disorder | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Diabetic encephalopathy | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Cryptorchism | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Blood 1,25-dihydroxycholecalciferol decreased | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Tibial torsion | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Carnitine palmitoyltransferase deficiency | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Mixed deafness | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Congenital cutis laxa | 15.35 | 10.27 | 3 | 111745 | 0 | 50493376 |
Injection site urticaria | 15.35 | 10.27 | 4 | 111744 | 12213 | 50481163 |
Regressive behaviour | 15.33 | 10.27 | 6 | 111742 | 74 | 50493302 |
Drug dependence | 15.32 | 10.27 | 85 | 111663 | 19674 | 50473702 |
Drug monitoring procedure incorrectly performed | 15.29 | 10.27 | 7 | 111741 | 130 | 50493246 |
Rib fracture | 15.29 | 10.27 | 12 | 111736 | 19209 | 50474167 |
Clonic convulsion | 15.25 | 10.27 | 12 | 111736 | 618 | 50492758 |
Device related infection | 15.20 | 10.27 | 14 | 111734 | 20721 | 50472655 |
Emotional disorder | 15.18 | 10.27 | 59 | 111689 | 11777 | 50481599 |
Sneezing | 15.16 | 10.27 | 6 | 111742 | 14038 | 50479338 |
Heart disease congenital | 15.13 | 10.27 | 16 | 111732 | 1210 | 50492166 |
Hospitalisation | 15.10 | 10.27 | 88 | 111660 | 67849 | 50425527 |
Live birth | 15.08 | 10.27 | 74 | 111674 | 16334 | 50477042 |
Systemic inflammatory response syndrome | 15.06 | 10.27 | 34 | 111714 | 5015 | 50488361 |
Epileptic psychosis | 15.03 | 10.27 | 5 | 111743 | 37 | 50493339 |
Developmental coordination disorder | 15.03 | 10.27 | 5 | 111743 | 37 | 50493339 |
Joint effusion | 15.01 | 10.27 | 5 | 111743 | 13016 | 50480360 |
Diabetes mellitus | 14.98 | 10.27 | 170 | 111578 | 48863 | 50444513 |
Premature baby | 14.97 | 10.27 | 80 | 111668 | 18257 | 50475119 |
Immunodeficiency | 14.95 | 10.27 | 7 | 111741 | 14821 | 50478555 |
Erythema multiforme | 14.94 | 10.27 | 49 | 111699 | 9001 | 50484375 |
Otitis media | 14.93 | 10.27 | 31 | 111717 | 4318 | 50489058 |
Glaucoma | 14.92 | 10.27 | 8 | 111740 | 15678 | 50477698 |
Magnetic resonance imaging head abnormal | 14.89 | 10.27 | 19 | 111729 | 1758 | 50491618 |
Hepatomegaly | 14.83 | 10.27 | 55 | 111693 | 10738 | 50482638 |
Acidosis | 14.80 | 10.27 | 53 | 111695 | 10174 | 50483202 |
Mental disability | 14.77 | 10.27 | 6 | 111742 | 82 | 50493294 |
Sinus bradycardia | 14.75 | 10.27 | 63 | 111685 | 13120 | 50480256 |
Blood urea decreased | 14.73 | 10.27 | 21 | 111727 | 2161 | 50491215 |
Autonomic nervous system imbalance | 14.72 | 10.27 | 22 | 111726 | 2363 | 50491013 |
Fine motor delay | 14.69 | 10.27 | 7 | 111741 | 143 | 50493233 |
Electrocardiogram T wave inversion | 14.58 | 10.27 | 26 | 111722 | 3235 | 50490141 |
Dysphonia | 14.58 | 10.27 | 41 | 111707 | 38851 | 50454525 |
Pulmonary valve stenosis congenital | 14.56 | 10.27 | 7 | 111741 | 146 | 50493230 |
Generalised anxiety disorder | 14.54 | 10.27 | 19 | 111729 | 1801 | 50491575 |
Simple partial seizures | 14.51 | 10.27 | 11 | 111737 | 536 | 50492840 |
Mucosal erosion | 14.49 | 10.27 | 16 | 111732 | 1271 | 50492105 |
Congenital eye disorder | 14.49 | 10.27 | 4 | 111744 | 14 | 50493362 |
Poor personal hygiene | 14.48 | 10.27 | 9 | 111739 | 316 | 50493060 |
Decreased activity | 14.45 | 10.27 | 34 | 111714 | 5153 | 50488223 |
Hypoproteinaemia | 14.45 | 10.27 | 19 | 111729 | 1812 | 50491564 |
Rash morbilliform | 14.45 | 10.27 | 24 | 111724 | 2822 | 50490554 |
Gastric disorder | 14.43 | 10.27 | 27 | 111721 | 29521 | 50463855 |
Electrocardiogram QRS complex shortened | 14.41 | 10.27 | 10 | 111738 | 424 | 50492952 |
Tubo-ovarian abscess | 14.40 | 10.27 | 9 | 111739 | 319 | 50493057 |
Grunting | 14.40 | 10.27 | 8 | 111740 | 227 | 50493149 |
Bradypnoea | 14.38 | 10.27 | 25 | 111723 | 3049 | 50490327 |
Incoherent | 14.35 | 10.27 | 30 | 111718 | 4200 | 50489176 |
Intestinal strangulation | 14.33 | 10.27 | 6 | 111742 | 89 | 50493287 |
Nodule | 14.32 | 10.27 | 10 | 111738 | 16993 | 50476383 |
Adenoidal hypertrophy | 14.27 | 10.27 | 5 | 111743 | 44 | 50493332 |
Diverticulum | 14.27 | 10.27 | 3 | 111745 | 10611 | 50482765 |
Congenital nipple anomaly | 14.27 | 10.27 | 4 | 111744 | 15 | 50493361 |
Choreoathetosis | 14.27 | 10.27 | 10 | 111738 | 431 | 50492945 |
Dry eye | 14.25 | 10.27 | 31 | 111717 | 32064 | 50461312 |
Gliosis | 14.15 | 10.27 | 8 | 111740 | 235 | 50493141 |
Acute myocardial infarction | 14.08 | 10.27 | 27 | 111721 | 29246 | 50464130 |
Hydrocephalus | 14.01 | 10.27 | 32 | 111716 | 4756 | 50488620 |
Faecal vomiting | 13.99 | 10.27 | 11 | 111737 | 566 | 50492810 |
Gallbladder disorder | 13.90 | 10.27 | 10 | 111738 | 16732 | 50476644 |
Candida infection | 13.84 | 10.27 | 19 | 111729 | 23504 | 50469872 |
Quadriparesis | 13.84 | 10.27 | 18 | 111730 | 1698 | 50491678 |
Idiosyncratic drug reaction | 13.83 | 10.27 | 12 | 111736 | 709 | 50492667 |
Haemorrhoids | 13.81 | 10.27 | 13 | 111735 | 19040 | 50474336 |
Thought blocking | 13.81 | 10.27 | 6 | 111742 | 98 | 50493278 |
Amniocentesis abnormal | 13.81 | 10.27 | 6 | 111742 | 98 | 50493278 |
Hyperkalaemia | 13.74 | 10.27 | 57 | 111691 | 48032 | 50445344 |
Ebstein's anomaly | 13.69 | 10.27 | 4 | 111744 | 18 | 50493358 |
Suspected suicide attempt | 13.59 | 10.27 | 6 | 111742 | 102 | 50493274 |
Tachypnoea | 13.58 | 10.27 | 66 | 111682 | 14511 | 50478865 |
Accidental poisoning | 13.58 | 10.27 | 11 | 111737 | 591 | 50492785 |
Intervertebral disc protrusion | 13.55 | 10.27 | 15 | 111733 | 20378 | 50472998 |
Withdrawal catatonia | 13.37 | 10.27 | 5 | 111743 | 54 | 50493322 |
Congenital laryngeal stridor | 13.37 | 10.27 | 5 | 111743 | 54 | 50493322 |
Crying | 13.36 | 10.27 | 84 | 111664 | 20332 | 50473044 |
Maternal exposure during breast feeding | 13.36 | 10.27 | 25 | 111723 | 3229 | 50490147 |
Coma hepatic | 13.35 | 10.27 | 11 | 111737 | 605 | 50492771 |
Spinal fracture | 13.33 | 10.27 | 9 | 111739 | 15564 | 50477812 |
Hypoglycaemia neonatal | 13.31 | 10.27 | 13 | 111735 | 895 | 50492481 |
Malignant melanoma | 13.30 | 10.27 | 3 | 111745 | 10105 | 50483271 |
Injection site warmth | 13.29 | 10.27 | 7 | 111741 | 13859 | 50479517 |
Deja vu | 13.29 | 10.27 | 5 | 111743 | 55 | 50493321 |
Blood pyruvic acid increased | 13.28 | 10.27 | 3 | 111745 | 3 | 50493373 |
Niemann-Pick disease | 13.28 | 10.27 | 3 | 111745 | 3 | 50493373 |
Cerebral palsy | 13.28 | 10.27 | 6 | 111742 | 108 | 50493268 |
Procedural pain | 13.23 | 10.27 | 7 | 111741 | 13825 | 50479551 |
Tympanic membrane disorder | 13.23 | 10.27 | 7 | 111741 | 180 | 50493196 |
Childhood asthma | 13.21 | 10.27 | 5 | 111743 | 56 | 50493320 |
Blood sodium increased | 13.20 | 10.27 | 21 | 111727 | 2381 | 50490995 |
Therapy interrupted | 13.19 | 10.27 | 15 | 111733 | 20137 | 50473239 |
Coma acidotic | 13.13 | 10.27 | 6 | 111742 | 111 | 50493265 |
Heart rate irregular | 13.13 | 10.27 | 14 | 111734 | 19346 | 50474030 |
Copper deficiency | 13.13 | 10.27 | 5 | 111743 | 57 | 50493319 |
Gamma-glutamyltransferase increased | 13.12 | 10.27 | 111 | 111637 | 29512 | 50463864 |
Haemorrhage | 13.10 | 10.27 | 67 | 111681 | 53374 | 50440002 |
Scoliosis | 13.08 | 10.27 | 38 | 111710 | 6538 | 50486838 |
Cell death | 13.06 | 10.27 | 20 | 111728 | 2195 | 50491181 |
Activated partial thromboplastin time abnormal | 12.98 | 10.27 | 6 | 111742 | 114 | 50493262 |
Febrile convulsion | 12.98 | 10.27 | 9 | 111739 | 381 | 50492995 |
Blood citric acid increased | 12.97 | 10.27 | 5 | 111743 | 59 | 50493317 |
Oral candidiasis | 12.91 | 10.27 | 11 | 111737 | 16904 | 50476472 |
Device difficult to use | 12.88 | 10.27 | 3 | 111745 | 9883 | 50483493 |
Status migrainosus | 12.84 | 10.27 | 6 | 111742 | 117 | 50493259 |
Cortical visual impairment | 12.82 | 10.27 | 3 | 111745 | 4 | 50493372 |
Benign rolandic epilepsy | 12.82 | 10.27 | 3 | 111745 | 4 | 50493372 |
Medication error | 12.81 | 10.27 | 129 | 111619 | 35975 | 50457401 |
Postictal state | 12.81 | 10.27 | 13 | 111735 | 937 | 50492439 |
Transaminases increased | 12.72 | 10.27 | 105 | 111643 | 27719 | 50465657 |
Joint hyperextension | 12.72 | 10.27 | 8 | 111740 | 287 | 50493089 |
Thermal burn | 12.70 | 10.27 | 31 | 111717 | 4810 | 50488566 |
Skin discolouration | 12.67 | 10.27 | 34 | 111714 | 32723 | 50460653 |
Perforation | 12.65 | 10.27 | 13 | 111735 | 951 | 50492425 |
Intervertebral disc degeneration | 12.61 | 10.27 | 7 | 111741 | 13454 | 50479922 |
Hand-eye coordination impaired | 12.60 | 10.27 | 4 | 111744 | 25 | 50493351 |
Exostosis | 12.54 | 10.27 | 5 | 111743 | 11648 | 50481728 |
Pancreatitis haemorrhagic | 12.52 | 10.27 | 8 | 111740 | 295 | 50493081 |
Aura | 12.50 | 10.27 | 13 | 111735 | 965 | 50492411 |
Epileptic aura | 12.47 | 10.27 | 5 | 111743 | 66 | 50493310 |
Laboratory test abnormal | 12.43 | 10.27 | 20 | 111728 | 23188 | 50470188 |
Therapeutic product ineffective for unapproved indication | 12.40 | 10.27 | 7 | 111741 | 205 | 50493171 |
Extensor plantar response | 12.40 | 10.27 | 14 | 111734 | 1140 | 50492236 |
Disorganised speech | 12.35 | 10.27 | 13 | 111735 | 978 | 50492398 |
Therapeutic response changed | 12.35 | 10.27 | 12 | 111736 | 821 | 50492555 |
Poisoning deliberate | 12.31 | 10.27 | 42 | 111706 | 7870 | 50485506 |
Rash pruritic | 12.29 | 10.27 | 59 | 111689 | 47787 | 50445589 |
Anxiety | 12.25 | 10.27 | 494 | 111254 | 177112 | 50316264 |
Gout | 12.22 | 10.27 | 5 | 111743 | 11465 | 50481911 |
High-pitched crying | 12.22 | 10.27 | 4 | 111744 | 28 | 50493348 |
Septic shock | 12.21 | 10.27 | 75 | 111673 | 57100 | 50436276 |
Eye swelling | 12.13 | 10.27 | 16 | 111732 | 20128 | 50473248 |
Blood bicarbonate increased | 12.11 | 10.27 | 11 | 111737 | 691 | 50492685 |
Food refusal | 12.08 | 10.27 | 8 | 111740 | 314 | 50493062 |
Enlarged foetal cisterna magna | 12.07 | 10.27 | 3 | 111745 | 6 | 50493370 |
Hypersomnia-bulimia syndrome | 12.07 | 10.27 | 3 | 111745 | 6 | 50493370 |
Congenital inguinal hernia | 12.07 | 10.27 | 3 | 111745 | 6 | 50493370 |
Congenital neurological disorder | 12.07 | 10.27 | 3 | 111745 | 6 | 50493370 |
Anuria | 12.02 | 10.27 | 53 | 111695 | 11191 | 50482185 |
Dissociative disorder | 12.02 | 10.27 | 7 | 111741 | 218 | 50493158 |
Liver function test increased | 11.98 | 10.27 | 24 | 111724 | 25582 | 50467794 |
Bronchiolitis | 11.98 | 10.27 | 20 | 111728 | 2361 | 50491015 |
Binocular eye movement disorder | 11.98 | 10.27 | 4 | 111744 | 30 | 50493346 |
Histiocytic necrotising lymphadenitis | 11.98 | 10.27 | 4 | 111744 | 30 | 50493346 |
Glassy eyes | 11.95 | 10.27 | 5 | 111743 | 74 | 50493302 |
Amino acid level increased | 11.94 | 10.27 | 8 | 111740 | 320 | 50493056 |
Slow response to stimuli | 11.92 | 10.27 | 12 | 111736 | 857 | 50492519 |
Presyncope | 11.92 | 10.27 | 22 | 111726 | 24176 | 50469200 |
Seasonal allergy | 11.88 | 10.27 | 9 | 111739 | 14667 | 50478709 |
Congenital hypothyroidism | 11.84 | 10.27 | 7 | 111741 | 224 | 50493152 |
Musculoskeletal chest pain | 11.84 | 10.27 | 14 | 111734 | 18472 | 50474904 |
Syndactyly | 11.83 | 10.27 | 8 | 111740 | 325 | 50493051 |
Movement disorder | 11.83 | 10.27 | 73 | 111675 | 17559 | 50475817 |
Hostility | 11.81 | 10.27 | 17 | 111731 | 1765 | 50491611 |
Nose deformity | 11.75 | 10.27 | 6 | 111742 | 143 | 50493233 |
Maternal drugs affecting foetus | 11.74 | 10.27 | 31 | 111717 | 5046 | 50488330 |
Encapsulating peritoneal sclerosis | 11.72 | 10.27 | 8 | 111740 | 330 | 50493046 |
Neutrophilia | 11.71 | 10.27 | 25 | 111723 | 3550 | 50489826 |
Toothache | 11.70 | 10.27 | 12 | 111736 | 16882 | 50476494 |
Viral infection | 11.70 | 10.27 | 31 | 111717 | 29955 | 50463421 |
Sudden death | 11.68 | 10.27 | 45 | 111703 | 8946 | 50484430 |
Brain stem syndrome | 11.66 | 10.27 | 8 | 111740 | 333 | 50493043 |
Hyperacusis | 11.65 | 10.27 | 17 | 111731 | 1787 | 50491589 |
Hyperaldosteronism | 11.65 | 10.27 | 7 | 111741 | 231 | 50493145 |
Lung disorder | 11.65 | 10.27 | 55 | 111693 | 44744 | 50448632 |
Convulsive threshold lowered | 11.57 | 10.27 | 8 | 111740 | 337 | 50493039 |
Inhibitory drug interaction | 11.56 | 10.27 | 19 | 111729 | 2214 | 50491162 |
Upper gastrointestinal haemorrhage | 11.55 | 10.27 | 11 | 111737 | 16024 | 50477352 |
Cerebral disorder | 11.54 | 10.27 | 25 | 111723 | 3586 | 50489790 |
Reproductive tract disorder | 11.49 | 10.27 | 6 | 111742 | 150 | 50493226 |
Electrocardiogram J wave | 11.47 | 10.27 | 3 | 111745 | 8 | 50493368 |
Tooth development disorder | 11.44 | 10.27 | 4 | 111744 | 35 | 50493341 |
Colitis | 11.43 | 10.27 | 45 | 111703 | 38484 | 50454892 |
Metastases to lung | 11.42 | 10.27 | 5 | 111743 | 11015 | 50482361 |
Blood osmolarity increased | 11.35 | 10.27 | 6 | 111742 | 154 | 50493222 |
Limb injury | 11.28 | 10.27 | 17 | 111731 | 20233 | 50473143 |
Congenital tracheomalacia | 11.24 | 10.27 | 4 | 111744 | 37 | 50493339 |
Procalcitonin increased | 11.24 | 10.27 | 11 | 111737 | 759 | 50492617 |
Pharyngeal disorder | 11.21 | 10.27 | 16 | 111732 | 1648 | 50491728 |
Congenital gastric anomaly | 11.21 | 10.27 | 3 | 111745 | 9 | 50493367 |
Congenital floppy infant | 11.21 | 10.27 | 3 | 111745 | 9 | 50493367 |
Intention tremor | 11.19 | 10.27 | 8 | 111740 | 356 | 50493020 |
Eosinophilic myocarditis | 11.17 | 10.27 | 8 | 111740 | 357 | 50493019 |
Persistent left superior vena cava | 11.15 | 10.27 | 4 | 111744 | 38 | 50493338 |
Device dislocation | 11.14 | 10.27 | 19 | 111729 | 21527 | 50471849 |
Hepatic steatosis | 11.13 | 10.27 | 92 | 111656 | 24292 | 50469084 |
Central nervous system lesion | 11.13 | 10.27 | 46 | 111702 | 9443 | 50483933 |
Respiratory tract congestion | 11.12 | 10.27 | 9 | 111739 | 14190 | 50479186 |
Sinus tachycardia | 11.09 | 10.27 | 83 | 111665 | 21271 | 50472105 |
Antidepressant drug level increased | 11.06 | 10.27 | 7 | 111741 | 254 | 50493122 |
Hyporesponsive to stimuli | 11.01 | 10.27 | 12 | 111736 | 940 | 50492436 |
Social problem | 11.00 | 10.27 | 11 | 111737 | 779 | 50492597 |
Nikolsky's sign | 10.97 | 10.27 | 5 | 111743 | 92 | 50493284 |
Eosinophilic pneumonia | 10.96 | 10.27 | 17 | 111731 | 1887 | 50491489 |
Body temperature decreased | 10.96 | 10.27 | 12 | 111736 | 16383 | 50476993 |
Homicidal ideation | 10.94 | 10.27 | 16 | 111732 | 1686 | 50491690 |
Palatal disorder | 10.93 | 10.27 | 7 | 111741 | 259 | 50493117 |
Postictal paralysis | 10.92 | 10.27 | 5 | 111743 | 93 | 50493283 |
Anomaly of external ear congenital | 10.91 | 10.27 | 6 | 111742 | 167 | 50493209 |
Enanthema | 10.90 | 10.27 | 8 | 111740 | 371 | 50493005 |
Myoglobinuria | 10.89 | 10.27 | 7 | 111741 | 261 | 50493115 |
Ageusia | 10.88 | 10.27 | 6 | 111742 | 11577 | 50481799 |
Delusional disorder, unspecified type | 10.86 | 10.27 | 8 | 111740 | 373 | 50493003 |
Skin disorder | 10.84 | 10.27 | 23 | 111725 | 24007 | 50469369 |
Congenital nail disorder | 10.82 | 10.27 | 5 | 111743 | 95 | 50493281 |
Rotator cuff syndrome | 10.81 | 10.27 | 6 | 111742 | 11538 | 50481838 |
Scar excision | 10.80 | 10.27 | 4 | 111744 | 42 | 50493334 |
Oppositional defiant disorder | 10.80 | 10.27 | 4 | 111744 | 42 | 50493334 |
Hypotension | 10.76 | 10.27 | 629 | 111119 | 234840 | 50258536 |
Congenital oesophageal anomaly | 10.76 | 10.27 | 3 | 111745 | 11 | 50493365 |
Aphthous ulcer | 10.69 | 10.27 | 5 | 111743 | 10592 | 50482784 |
Impaired gastric emptying | 10.68 | 10.27 | 3 | 111745 | 8715 | 50484661 |
Arrhythmia | 10.64 | 10.27 | 116 | 111632 | 33016 | 50460360 |
Tenosynovitis | 10.63 | 10.27 | 5 | 111743 | 10560 | 50482816 |
Carpal tunnel syndrome | 10.60 | 10.27 | 13 | 111735 | 16880 | 50476496 |
Delusion of reference | 10.59 | 10.27 | 5 | 111743 | 100 | 50493276 |
Parkinsonian rest tremor | 10.59 | 10.27 | 5 | 111743 | 100 | 50493276 |
Toe walking | 10.55 | 10.27 | 3 | 111745 | 12 | 50493364 |
Transplant rejection | 10.55 | 10.27 | 4 | 111744 | 9605 | 50483771 |
Colitis ulcerative | 10.55 | 10.27 | 13 | 111735 | 16841 | 50476535 |
Hepatic adenoma | 10.52 | 10.27 | 7 | 111741 | 277 | 50493099 |
Peripheral nerve injury | 10.48 | 10.27 | 8 | 111740 | 394 | 50492982 |
Influenza like illness | 10.46 | 10.27 | 79 | 111669 | 57380 | 50435996 |
Head deformity | 10.45 | 10.27 | 5 | 111743 | 103 | 50493273 |
Hernia | 10.43 | 10.27 | 4 | 111744 | 9539 | 50483837 |
Wound infection | 10.42 | 10.27 | 7 | 111741 | 12141 | 50481235 |
Disease recurrence | 10.40 | 10.27 | 78 | 111670 | 20003 | 50473373 |
Deformity thorax | 10.36 | 10.27 | 3 | 111745 | 13 | 50493363 |
Urine calcium decreased | 10.36 | 10.27 | 3 | 111745 | 13 | 50493363 |
Dyspepsia | 10.36 | 10.27 | 109 | 111639 | 73988 | 50419388 |
Xanthoma | 10.32 | 10.27 | 4 | 111744 | 48 | 50493328 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Seizure | 1553.84 | 11.59 | 1926 | 121588 | 91197 | 29359816 |
Hyperammonaemia | 1170.81 | 11.59 | 539 | 122975 | 5124 | 29445889 |
Drug interaction | 925.61 | 11.59 | 2331 | 121183 | 195054 | 29255959 |
Foetal anticonvulsant syndrome | 921.38 | 11.59 | 295 | 123219 | 869 | 29450144 |
Dysmorphism | 902.54 | 11.59 | 371 | 123143 | 2600 | 29448413 |
Aggression | 799.58 | 11.59 | 859 | 122655 | 34682 | 29416331 |
Hyperammonaemic encephalopathy | 727.54 | 11.59 | 284 | 123230 | 1706 | 29449307 |
Neuroleptic malignant syndrome | 691.66 | 11.59 | 559 | 122955 | 15589 | 29435424 |
Foetal exposure during pregnancy | 667.64 | 11.59 | 764 | 122750 | 33103 | 29417910 |
Status epilepticus | 580.97 | 11.59 | 428 | 123086 | 10366 | 29440647 |
Autism spectrum disorder | 580.88 | 11.59 | 243 | 123271 | 1789 | 29449224 |
Somnolence | 534.18 | 11.59 | 1198 | 122316 | 92757 | 29358256 |
Speech disorder developmental | 491.84 | 11.59 | 212 | 123302 | 1695 | 29449318 |
Epilepsy | 459.74 | 11.59 | 471 | 123043 | 17961 | 29433052 |
Developmental delay | 438.47 | 11.59 | 213 | 123301 | 2305 | 29448708 |
Dyspnoea | 427.77 | 11.59 | 442 | 123072 | 326290 | 29124723 |
Generalised tonic-clonic seizure | 420.29 | 11.59 | 457 | 123057 | 18682 | 29432331 |
Ammonia increased | 393.62 | 11.59 | 232 | 123282 | 3799 | 29447214 |
Learning disorder | 384.71 | 11.59 | 149 | 123365 | 873 | 29450140 |
Abnormal behaviour | 377.19 | 11.59 | 474 | 123040 | 22653 | 29428360 |
Sopor | 376.60 | 11.59 | 334 | 123180 | 10600 | 29440413 |
Diarrhoea | 375.53 | 11.59 | 506 | 123008 | 332192 | 29118821 |
Mania | 375.29 | 11.59 | 302 | 123212 | 8361 | 29442652 |
Psychomotor retardation | 373.80 | 11.59 | 202 | 123312 | 2774 | 29448239 |
Agitation | 336.83 | 11.59 | 694 | 122820 | 50610 | 29400403 |
Intellectual disability | 331.80 | 11.59 | 138 | 123376 | 999 | 29450014 |
Cognitive disorder | 330.88 | 11.59 | 448 | 123066 | 23051 | 29427962 |
Extrapyramidal disorder | 330.26 | 11.59 | 309 | 123205 | 10522 | 29440491 |
Language disorder | 329.96 | 11.59 | 162 | 123352 | 1797 | 29449216 |
Psychotic disorder | 328.46 | 11.59 | 415 | 123099 | 19939 | 29431074 |
Sedation | 323.24 | 11.59 | 381 | 123133 | 17024 | 29433989 |
Parkinsonism | 320.11 | 11.59 | 256 | 123258 | 7022 | 29443991 |
Granulocytopenia | 316.47 | 11.59 | 235 | 123279 | 5759 | 29445254 |
Behaviour disorder | 301.29 | 11.59 | 188 | 123326 | 3428 | 29447585 |
Depression | 293.46 | 11.59 | 901 | 122613 | 84246 | 29366767 |
Febrile neutropenia | 282.00 | 11.59 | 62 | 123452 | 112178 | 29338835 |
Death | 275.66 | 11.59 | 642 | 122872 | 341442 | 29109571 |
Arthralgia | 272.68 | 11.59 | 121 | 123393 | 139496 | 29311517 |
Disturbance in attention | 268.12 | 11.59 | 386 | 123128 | 21038 | 29429975 |
Psychomotor skills impaired | 267.31 | 11.59 | 156 | 123358 | 2505 | 29448508 |
Coma | 255.72 | 11.59 | 531 | 122983 | 38919 | 29412094 |
Schizophrenia | 253.28 | 11.59 | 214 | 123300 | 6351 | 29444662 |
Petit mal epilepsy | 251.00 | 11.59 | 151 | 123363 | 2571 | 29448442 |
Attention deficit hyperactivity disorder | 244.16 | 11.59 | 138 | 123376 | 2079 | 29448934 |
Acute kidney injury | 242.60 | 11.59 | 463 | 123051 | 264804 | 29186209 |
Congenital nose malformation | 231.35 | 11.59 | 68 | 123446 | 134 | 29450879 |
Nausea | 227.04 | 11.59 | 550 | 122964 | 288705 | 29162308 |
Hypospadias | 222.57 | 11.59 | 145 | 123369 | 2857 | 29448156 |
Fatigue | 222.43 | 11.59 | 637 | 122877 | 316184 | 29134829 |
Dysgraphia | 222.12 | 11.59 | 126 | 123388 | 1912 | 29449101 |
Salivary hypersecretion | 221.30 | 11.59 | 209 | 123305 | 7200 | 29443813 |
Toxicity to various agents | 216.89 | 11.59 | 1352 | 122162 | 172309 | 29278704 |
Anaemia | 214.72 | 11.59 | 317 | 123197 | 200634 | 29250379 |
Irritability | 209.82 | 11.59 | 351 | 123163 | 21801 | 29429212 |
Psychomotor hyperactivity | 204.94 | 11.59 | 210 | 123304 | 8003 | 29443010 |
Multiple-drug resistance | 203.85 | 11.59 | 152 | 123362 | 3748 | 29447265 |
Antipsychotic drug level increased | 202.95 | 11.59 | 141 | 123373 | 3102 | 29447911 |
Atrial fibrillation | 202.36 | 11.59 | 94 | 123420 | 105552 | 29345461 |
Drug level increased | 201.53 | 11.59 | 315 | 123199 | 18472 | 29432541 |
Myocardial infarction | 197.95 | 11.59 | 107 | 123407 | 110189 | 29340824 |
Drug level decreased | 195.78 | 11.59 | 181 | 123333 | 6066 | 29444947 |
Intentional overdose | 192.95 | 11.59 | 468 | 123046 | 38060 | 29412953 |
Intentional self-injury | 191.42 | 11.59 | 248 | 123266 | 12213 | 29438800 |
Ataxia | 189.25 | 11.59 | 243 | 123271 | 11860 | 29439153 |
Pain | 186.42 | 11.59 | 267 | 123247 | 171165 | 29279848 |
Hypertelorism | 184.12 | 11.59 | 74 | 123440 | 485 | 29450528 |
Akathisia | 184.04 | 11.59 | 181 | 123333 | 6561 | 29444452 |
Cardiac failure congestive | 183.00 | 11.59 | 47 | 123467 | 76534 | 29374479 |
Speech disorder | 180.67 | 11.59 | 340 | 123174 | 23176 | 29427837 |
Tremor | 175.42 | 11.59 | 689 | 122825 | 72849 | 29378164 |
Suicide attempt | 174.72 | 11.59 | 418 | 123096 | 33692 | 29417321 |
Mental impairment | 174.50 | 11.59 | 203 | 123311 | 8938 | 29442075 |
Electroencephalogram abnormal | 171.19 | 11.59 | 112 | 123402 | 2223 | 29448790 |
Depressed level of consciousness | 170.51 | 11.59 | 435 | 123079 | 36507 | 29414506 |
Gastrointestinal haemorrhage | 169.78 | 11.59 | 60 | 123454 | 79473 | 29371540 |
Hypotonia | 169.53 | 11.59 | 175 | 123339 | 6727 | 29444286 |
Pneumonia | 169.28 | 11.59 | 726 | 122788 | 319446 | 29131567 |
Pain in extremity | 167.03 | 11.59 | 130 | 123384 | 110303 | 29340710 |
Overdose | 164.55 | 11.59 | 715 | 122799 | 79104 | 29371909 |
Blood creatine phosphokinase increased | 163.71 | 11.59 | 455 | 123059 | 40189 | 29410824 |
Neuropathy peripheral | 161.46 | 11.59 | 48 | 123466 | 70979 | 29380034 |
Anticonvulsant drug level increased | 158.06 | 11.59 | 90 | 123424 | 1376 | 29449637 |
Enuresis | 157.79 | 11.59 | 102 | 123412 | 1982 | 29449031 |
Astigmatism | 156.32 | 11.59 | 78 | 123436 | 898 | 29450115 |
Delusion | 155.03 | 11.59 | 212 | 123302 | 11004 | 29440009 |
Catatonia | 154.84 | 11.59 | 137 | 123377 | 4331 | 29446682 |
Hallucination, auditory | 152.17 | 11.59 | 194 | 123320 | 9399 | 29441614 |
Muscle rigidity | 150.36 | 11.59 | 191 | 123323 | 9220 | 29441793 |
Anticonvulsant drug level decreased | 147.34 | 11.59 | 76 | 123438 | 943 | 29450070 |
Dystonia | 146.58 | 11.59 | 192 | 123322 | 9557 | 29441456 |
Motor developmental delay | 146.37 | 11.59 | 66 | 123448 | 594 | 29450419 |
Talipes | 146.34 | 11.59 | 92 | 123422 | 1700 | 29449313 |
Tardive dyskinesia | 145.08 | 11.59 | 142 | 123372 | 5116 | 29445897 |
Product residue present | 144.09 | 11.59 | 104 | 123410 | 2435 | 29448578 |
Malignant neoplasm progression | 144.05 | 11.59 | 64 | 123450 | 73795 | 29377218 |
Antipsychotic drug level below therapeutic | 140.62 | 11.59 | 93 | 123421 | 1881 | 29449132 |
Partial seizures | 139.91 | 11.59 | 122 | 123392 | 3781 | 29447232 |
Disease progression | 139.02 | 11.59 | 85 | 123429 | 81831 | 29369182 |
Product substitution issue | 138.46 | 11.59 | 181 | 123333 | 8991 | 29442022 |
Neurodevelopmental disorder | 136.66 | 11.59 | 52 | 123462 | 288 | 29450725 |
Dyspraxia | 135.25 | 11.59 | 54 | 123460 | 347 | 29450666 |
Strabismus | 134.32 | 11.59 | 80 | 123434 | 1336 | 29449677 |
Interstitial lung disease | 131.18 | 11.59 | 39 | 123475 | 57679 | 29393334 |
Foot deformity | 131.01 | 11.59 | 119 | 123395 | 3896 | 29447117 |
Wrong patient received product | 130.71 | 11.59 | 94 | 123420 | 2188 | 29448825 |
Lip disorder | 129.87 | 11.59 | 52 | 123462 | 337 | 29450676 |
Dyskinesia | 128.71 | 11.59 | 269 | 123245 | 19792 | 29431221 |
Joint swelling | 127.43 | 11.59 | 26 | 123488 | 49604 | 29401409 |
Mental disorder | 126.89 | 11.59 | 208 | 123306 | 12697 | 29438316 |
Asthenia | 126.88 | 11.59 | 467 | 123047 | 214783 | 29236230 |
Learning disability | 125.54 | 11.59 | 48 | 123466 | 270 | 29450743 |
Paranoia | 125.05 | 11.59 | 179 | 123335 | 9698 | 29441315 |
Peripheral swelling | 123.08 | 11.59 | 56 | 123458 | 63683 | 29387330 |
Treatment noncompliance | 123.08 | 11.59 | 296 | 123218 | 23931 | 29427082 |
Renal failure | 119.84 | 11.59 | 194 | 123320 | 118405 | 29332608 |
Myopia | 119.09 | 11.59 | 65 | 123449 | 911 | 29450102 |
Delirium | 118.32 | 11.59 | 398 | 123116 | 38999 | 29412014 |
Cryptorchism | 118.17 | 11.59 | 83 | 123431 | 1859 | 29449154 |
Plasma cell myeloma | 117.68 | 11.59 | 10 | 123504 | 37105 | 29413908 |
Encephalopathy | 117.63 | 11.59 | 340 | 123174 | 30703 | 29420310 |
Drug reaction with eosinophilia and systemic symptoms | 117.29 | 11.59 | 318 | 123196 | 27674 | 29423339 |
Infusion related reaction | 116.89 | 11.59 | 21 | 123493 | 43865 | 29407148 |
Communication disorder | 116.56 | 11.59 | 89 | 123425 | 2276 | 29448737 |
Cough | 116.52 | 11.59 | 220 | 123294 | 126507 | 29324506 |
Myoclonic epilepsy | 116.39 | 11.59 | 64 | 123450 | 911 | 29450102 |
Chest pain | 116.12 | 11.59 | 180 | 123334 | 111793 | 29339220 |
Euphoric mood | 116.09 | 11.59 | 121 | 123393 | 4704 | 29446309 |
Joint laxity | 115.33 | 11.59 | 48 | 123466 | 348 | 29450665 |
Thrombosis | 111.66 | 11.59 | 22 | 123492 | 43023 | 29407990 |
Educational problem | 111.50 | 11.59 | 51 | 123463 | 476 | 29450537 |
Congenital oral malformation | 111.17 | 11.59 | 26 | 123488 | 6 | 29451007 |
Dysarthria | 110.86 | 11.59 | 332 | 123182 | 30579 | 29420434 |
Altered state of consciousness | 110.85 | 11.59 | 252 | 123262 | 19637 | 29431376 |
Hypotonia neonatal | 109.77 | 11.59 | 67 | 123447 | 1172 | 29449841 |
Pruritus | 109.05 | 11.59 | 201 | 123313 | 116648 | 29334365 |
Fanconi syndrome | 108.33 | 11.59 | 73 | 123441 | 1525 | 29449488 |
Sudden unexplained death in epilepsy | 105.59 | 11.59 | 47 | 123467 | 409 | 29450604 |
Bradyphrenia | 105.57 | 11.59 | 108 | 123406 | 4106 | 29446907 |
Disinhibition | 104.72 | 11.59 | 87 | 123427 | 2520 | 29448493 |
Restlessness | 104.47 | 11.59 | 263 | 123251 | 21882 | 29429131 |
Back pain | 103.60 | 11.59 | 167 | 123347 | 102117 | 29348896 |
Obsessive-compulsive disorder | 103.42 | 11.59 | 111 | 123403 | 4465 | 29446548 |
Thinking abnormal | 99.46 | 11.59 | 116 | 123398 | 5120 | 29445893 |
Myocarditis | 98.94 | 11.59 | 170 | 123344 | 10786 | 29440227 |
Myalgia | 98.73 | 11.59 | 98 | 123416 | 73921 | 29377092 |
Suicidal ideation | 98.36 | 11.59 | 344 | 123170 | 34372 | 29416641 |
Low set ears | 97.87 | 11.59 | 44 | 123470 | 393 | 29450620 |
Coordination abnormal | 97.60 | 11.59 | 134 | 123380 | 6980 | 29444033 |
Anticonvulsant drug level below therapeutic | 97.08 | 11.59 | 49 | 123465 | 579 | 29450434 |
Schizoaffective disorder | 96.62 | 11.59 | 59 | 123455 | 1033 | 29449980 |
Priapism | 96.43 | 11.59 | 106 | 123408 | 4382 | 29446631 |
Abdominal pain | 95.40 | 11.59 | 271 | 123243 | 135086 | 29315927 |
Oedema peripheral | 94.96 | 11.59 | 180 | 123334 | 103377 | 29347636 |
Acute myocardial infarction | 94.37 | 11.59 | 42 | 123472 | 48396 | 29402617 |
Focal dyscognitive seizures | 94.37 | 11.59 | 61 | 123453 | 1185 | 29449828 |
Sepsis | 93.85 | 11.59 | 295 | 123219 | 142387 | 29308626 |
Disorientation | 93.82 | 11.59 | 304 | 123210 | 29211 | 29421802 |
Drug level below therapeutic | 93.72 | 11.59 | 102 | 123412 | 4169 | 29446844 |
Drooling | 93.63 | 11.59 | 87 | 123427 | 2934 | 29448079 |
Fine motor delay | 93.21 | 11.59 | 36 | 123478 | 209 | 29450804 |
Coronary artery disease | 93.13 | 11.59 | 34 | 123480 | 44156 | 29406857 |
Pectus excavatum | 92.86 | 11.59 | 35 | 123479 | 188 | 29450825 |
Hypertonia | 92.08 | 11.59 | 96 | 123418 | 3733 | 29447280 |
Congenital foot malformation | 91.80 | 11.59 | 41 | 123473 | 360 | 29450653 |
Ear disorder | 90.70 | 11.59 | 60 | 123454 | 1214 | 29449799 |
Cardiac failure | 90.53 | 11.59 | 119 | 123395 | 79168 | 29371845 |
Hypermetropia | 89.42 | 11.59 | 41 | 123473 | 385 | 29450628 |
Congenital hand malformation | 88.84 | 11.59 | 45 | 123469 | 536 | 29450477 |
Drug ineffective | 87.68 | 11.59 | 2057 | 121457 | 361113 | 29089900 |
Myoclonus | 87.16 | 11.59 | 180 | 123334 | 13129 | 29437884 |
Anticonvulsant drug level above therapeutic | 86.44 | 11.59 | 44 | 123470 | 530 | 29450483 |
Pneumonia aspiration | 85.71 | 11.59 | 342 | 123172 | 36395 | 29414618 |
Chest discomfort | 84.78 | 11.59 | 43 | 123471 | 45940 | 29405073 |
Scoliosis | 84.67 | 11.59 | 73 | 123441 | 2227 | 29448786 |
Asterixis | 83.90 | 11.59 | 54 | 123460 | 1041 | 29449972 |
Psychogenic seizure | 83.22 | 11.59 | 37 | 123477 | 321 | 29450692 |
Mucosal inflammation | 82.25 | 11.59 | 16 | 123498 | 31579 | 29419434 |
Hyperkalaemia | 82.19 | 11.59 | 81 | 123433 | 61311 | 29389702 |
Prominent epicanthal folds | 82.18 | 11.59 | 30 | 123484 | 145 | 29450868 |
Echolalia | 82.10 | 11.59 | 34 | 123480 | 243 | 29450770 |
Antipsychotic drug level above therapeutic | 81.17 | 11.59 | 53 | 123461 | 1048 | 29449965 |
Dizziness | 80.97 | 11.59 | 463 | 123051 | 189221 | 29261792 |
Ligament laxity | 79.69 | 11.59 | 20 | 123494 | 13 | 29451000 |
Eosinophilia | 79.43 | 11.59 | 238 | 123276 | 21923 | 29429090 |
Disturbance in social behaviour | 79.41 | 11.59 | 62 | 123452 | 1640 | 29449373 |
Chills | 79.38 | 11.59 | 109 | 123405 | 71191 | 29379822 |
Hypothermia | 79.06 | 11.59 | 140 | 123374 | 9099 | 29441914 |
Increased appetite | 78.38 | 11.59 | 111 | 123403 | 5953 | 29445060 |
Pulmonary embolism | 78.37 | 11.59 | 124 | 123390 | 76410 | 29374603 |
Impulsive behaviour | 78.37 | 11.59 | 65 | 123449 | 1878 | 29449135 |
Blood pressure increased | 78.04 | 11.59 | 117 | 123397 | 73686 | 29377327 |
Affect lability | 77.73 | 11.59 | 83 | 123431 | 3319 | 29447694 |
Clinodactyly | 77.72 | 11.59 | 32 | 123482 | 225 | 29450788 |
Anger | 76.93 | 11.59 | 152 | 123362 | 10738 | 29440275 |
Developmental coordination disorder | 76.91 | 11.59 | 29 | 123485 | 156 | 29450857 |
Bipolar disorder | 76.36 | 11.59 | 81 | 123433 | 3214 | 29447799 |
Drug withdrawal convulsions | 76.23 | 11.59 | 52 | 123462 | 1109 | 29449904 |
Prostate cancer | 75.40 | 11.59 | 9 | 123505 | 25518 | 29425495 |
Oppositional defiant disorder | 75.04 | 11.59 | 39 | 123475 | 492 | 29450521 |
Prescribed overdose | 73.56 | 11.59 | 131 | 123383 | 8552 | 29442461 |
Fine motor skill dysfunction | 73.45 | 11.59 | 57 | 123457 | 1494 | 29449519 |
Epistaxis | 72.99 | 11.59 | 65 | 123449 | 51639 | 29399374 |
Stereotypy | 72.51 | 11.59 | 41 | 123473 | 618 | 29450395 |
Headache | 72.49 | 11.59 | 428 | 123086 | 173579 | 29277434 |
Hypernatraemia | 71.19 | 11.59 | 118 | 123396 | 7268 | 29443745 |
Oculogyric crisis | 71.02 | 11.59 | 53 | 123461 | 1308 | 29449705 |
Dyspnoea exertional | 70.51 | 11.59 | 32 | 123482 | 36458 | 29414555 |
Microcephaly | 70.17 | 11.59 | 42 | 123472 | 708 | 29450305 |
Persecutory delusion | 68.96 | 11.59 | 63 | 123451 | 2078 | 29448935 |
Obesity | 68.87 | 11.59 | 137 | 123377 | 9726 | 29441287 |
Personal relationship issue | 68.41 | 11.59 | 30 | 123484 | 251 | 29450762 |
Hypomania | 68.11 | 11.59 | 63 | 123451 | 2112 | 29448901 |
Nasal disorder | 68.07 | 11.59 | 53 | 123461 | 1396 | 29449617 |
Therapeutic product effect variable | 67.94 | 11.59 | 59 | 123455 | 1818 | 29449195 |
Congenital anomaly | 67.71 | 11.59 | 51 | 123463 | 1277 | 29449736 |
Influenza | 67.54 | 11.59 | 46 | 123468 | 41835 | 29409178 |
Dyslexia | 66.71 | 11.59 | 31 | 123483 | 301 | 29450712 |
Stevens-Johnson syndrome | 66.68 | 11.59 | 185 | 123329 | 16312 | 29434701 |
Urticaria | 66.61 | 11.59 | 78 | 123436 | 54582 | 29396431 |
Muscle spasms | 66.10 | 11.59 | 106 | 123408 | 64976 | 29386037 |
Personality disorder | 66.02 | 11.59 | 47 | 123467 | 1076 | 29449937 |
Renal impairment | 65.59 | 11.59 | 152 | 123362 | 81181 | 29369832 |
Ascites | 64.92 | 11.59 | 36 | 123478 | 36583 | 29414430 |
Weight decreased | 64.53 | 11.59 | 368 | 123146 | 150537 | 29300476 |
Dysphoria | 64.36 | 11.59 | 60 | 123454 | 2032 | 29448981 |
Toxic encephalopathy | 63.46 | 11.59 | 87 | 123427 | 4525 | 29446488 |
Nystagmus | 63.43 | 11.59 | 84 | 123430 | 4225 | 29446788 |
Cerebrovascular accident | 63.43 | 11.59 | 142 | 123372 | 76769 | 29374244 |
Neutrophil count increased | 63.26 | 11.59 | 169 | 123345 | 14573 | 29436440 |
Bradykinesia | 63.20 | 11.59 | 75 | 123439 | 3372 | 29447641 |
Plagiocephaly | 62.83 | 11.59 | 34 | 123480 | 468 | 29450545 |
Bipolar I disorder | 62.73 | 11.59 | 39 | 123475 | 706 | 29450307 |
Psoriasis | 62.68 | 11.59 | 28 | 123486 | 32199 | 29418814 |
Sleep disorder | 62.57 | 11.59 | 234 | 123280 | 24152 | 29426861 |
Ear malformation | 62.55 | 11.59 | 29 | 123485 | 280 | 29450733 |
Atonic seizures | 62.31 | 11.59 | 25 | 123489 | 163 | 29450850 |
Craniosynostosis | 62.19 | 11.59 | 29 | 123485 | 284 | 29450729 |
Hypermobility syndrome | 61.47 | 11.59 | 30 | 123484 | 328 | 29450685 |
Decreased eye contact | 61.12 | 11.59 | 33 | 123481 | 452 | 29450561 |
Abdominal pain upper | 60.39 | 11.59 | 101 | 123413 | 60892 | 29390121 |
Hepatic function abnormal | 60.07 | 11.59 | 323 | 123191 | 38936 | 29412077 |
Hypersensitivity | 59.75 | 11.59 | 80 | 123434 | 52823 | 29398190 |
Confusional state | 59.68 | 11.59 | 805 | 122709 | 127072 | 29323941 |
Pancytopenia | 59.66 | 11.59 | 165 | 123349 | 83003 | 29368010 |
Erythema | 59.60 | 11.59 | 143 | 123371 | 75463 | 29375550 |
Stupor | 59.28 | 11.59 | 65 | 123449 | 2679 | 29448334 |
Melaena | 59.21 | 11.59 | 28 | 123486 | 31148 | 29419865 |
Fluid retention | 59.11 | 11.59 | 13 | 123501 | 23547 | 29427466 |
Dehydration | 58.61 | 11.59 | 263 | 123251 | 114485 | 29336528 |
Nose deformity | 58.14 | 11.59 | 24 | 123490 | 170 | 29450843 |
Serotonin syndrome | 58.03 | 11.59 | 183 | 123331 | 17329 | 29433684 |
Weight increased | 57.98 | 11.59 | 531 | 122983 | 76136 | 29374877 |
Psychiatric symptom | 57.92 | 11.59 | 69 | 123445 | 3115 | 29447898 |
Angina pectoris | 57.71 | 11.59 | 22 | 123492 | 27828 | 29423185 |
Brain oedema | 57.48 | 11.59 | 145 | 123369 | 12075 | 29438938 |
Antipsychotic drug level decreased | 57.24 | 11.59 | 39 | 123475 | 830 | 29450183 |
Herpes zoster | 57.06 | 11.59 | 27 | 123487 | 30025 | 29420988 |
Postictal psychosis | 57.06 | 11.59 | 23 | 123491 | 152 | 29450861 |
Haematochezia | 56.52 | 11.59 | 43 | 123471 | 36940 | 29414073 |
Psychotic symptom | 56.40 | 11.59 | 47 | 123467 | 1367 | 29449646 |
Hypoaesthesia | 56.28 | 11.59 | 85 | 123429 | 53382 | 29397631 |
Eosinophilic pleural effusion | 56.19 | 11.59 | 24 | 123490 | 187 | 29450826 |
Sedation complication | 56.16 | 11.59 | 45 | 123469 | 1237 | 29449776 |
Arthritis | 54.86 | 11.59 | 18 | 123496 | 25001 | 29426012 |
Pressure of speech | 54.50 | 11.59 | 30 | 123484 | 428 | 29450585 |
Completed suicide | 54.22 | 11.59 | 596 | 122918 | 89650 | 29361363 |
Exposure during pregnancy | 54.03 | 11.59 | 114 | 123400 | 8440 | 29442573 |
Blood creatinine increased | 53.77 | 11.59 | 179 | 123335 | 84923 | 29366090 |
Sinusitis | 53.71 | 11.59 | 39 | 123475 | 34311 | 29416702 |
Septic shock | 53.65 | 11.59 | 113 | 123401 | 62447 | 29388566 |
Syncope | 53.60 | 11.59 | 168 | 123346 | 81203 | 29369810 |
Musculoskeletal pain | 53.47 | 11.59 | 27 | 123487 | 28926 | 29422087 |
Hyperkinesia | 53.36 | 11.59 | 48 | 123466 | 1551 | 29449462 |
White blood cell count increased | 52.29 | 11.59 | 301 | 123213 | 37215 | 29413798 |
Camptodactyly congenital | 52.18 | 11.59 | 19 | 123495 | 91 | 29450922 |
Congenital eyelid malformation | 51.84 | 11.59 | 16 | 123498 | 40 | 29450973 |
Reading disorder | 51.76 | 11.59 | 29 | 123485 | 429 | 29450584 |
Urinary incontinence | 51.68 | 11.59 | 169 | 123345 | 16312 | 29434701 |
Congenital eye disorder | 51.66 | 11.59 | 20 | 123494 | 117 | 29450896 |
Upper gastrointestinal haemorrhage | 51.26 | 11.59 | 14 | 123500 | 21900 | 29429113 |
Ear infection | 51.22 | 11.59 | 108 | 123406 | 7992 | 29443021 |
Chronic kidney disease | 51.13 | 11.59 | 46 | 123468 | 36370 | 29414643 |
Loss of personal independence in daily activities | 50.88 | 11.59 | 226 | 123288 | 25214 | 29425799 |
Osteonecrosis of jaw | 50.85 | 11.59 | 5 | 123509 | 16505 | 29434508 |
Atrial septal defect | 50.68 | 11.59 | 97 | 123417 | 6692 | 29444321 |
General physical health deterioration | 50.59 | 11.59 | 239 | 123275 | 102618 | 29348395 |
Anaphylactic reaction | 50.49 | 11.59 | 26 | 123488 | 27547 | 29423466 |
Haemoptysis | 50.00 | 11.59 | 33 | 123481 | 30517 | 29420496 |
Basal cell carcinoma | 49.85 | 11.59 | 6 | 123508 | 16904 | 29434109 |
Asocial behaviour | 49.50 | 11.59 | 16 | 123498 | 49 | 29450964 |
Rectal haemorrhage | 49.27 | 11.59 | 43 | 123471 | 34506 | 29416507 |
Social avoidant behaviour | 49.04 | 11.59 | 61 | 123453 | 2881 | 29448132 |
Knee deformity | 48.84 | 11.59 | 30 | 123484 | 531 | 29450482 |
Motor dysfunction | 48.36 | 11.59 | 88 | 123426 | 5842 | 29445171 |
Drug level changed | 48.34 | 11.59 | 25 | 123489 | 312 | 29450701 |
Differential white blood cell count abnormal | 48.19 | 11.59 | 41 | 123473 | 1228 | 29449785 |
Hyperacusis | 47.84 | 11.59 | 33 | 123481 | 717 | 29450296 |
Tonic convulsion | 47.84 | 11.59 | 36 | 123478 | 900 | 29450113 |
Bruxism | 47.83 | 11.59 | 45 | 123469 | 1542 | 29449471 |
High arched palate | 47.46 | 11.59 | 16 | 123498 | 58 | 29450955 |
Leukopenia | 47.26 | 11.59 | 393 | 123121 | 54810 | 29396203 |
Spina bifida | 47.18 | 11.59 | 25 | 123489 | 329 | 29450684 |
Swelling | 46.69 | 11.59 | 47 | 123467 | 35236 | 29415777 |
Arnold-Chiari malformation | 46.65 | 11.59 | 24 | 123490 | 296 | 29450717 |
Cerebral ventricle dilatation | 46.38 | 11.59 | 34 | 123480 | 816 | 29450197 |
Diabetes insipidus | 46.35 | 11.59 | 54 | 123460 | 2380 | 29448633 |
Gait disturbance | 46.17 | 11.59 | 489 | 123025 | 72860 | 29378153 |
Lethargy | 45.69 | 11.59 | 291 | 123223 | 37289 | 29413724 |
Rash | 45.68 | 11.59 | 540 | 122974 | 189279 | 29261734 |
Cytomegalovirus infection | 45.41 | 11.59 | 20 | 123494 | 23195 | 29427818 |
Gaze palsy | 45.34 | 11.59 | 40 | 123474 | 1259 | 29449754 |
Hyperosmolar state | 44.97 | 11.59 | 25 | 123489 | 364 | 29450649 |
Pneumonitis | 44.95 | 11.59 | 31 | 123483 | 28013 | 29423000 |
Congenital hair disorder | 44.83 | 11.59 | 10 | 123504 | 0 | 29451013 |
Paraesthesia | 44.72 | 11.59 | 99 | 123415 | 53746 | 29397267 |
Malaise | 44.43 | 11.59 | 439 | 123075 | 159163 | 29291850 |
Normal pressure hydrocephalus | 44.27 | 11.59 | 19 | 123495 | 150 | 29450863 |
Excessive eye blinking | 44.19 | 11.59 | 26 | 123488 | 424 | 29450589 |
Memory impairment | 44.09 | 11.59 | 282 | 123232 | 36188 | 29414825 |
Homicidal ideation | 43.14 | 11.59 | 53 | 123461 | 2471 | 29448542 |
Cytokine release syndrome | 43.09 | 11.59 | 3 | 123511 | 13116 | 29437897 |
Arthropathy | 43.07 | 11.59 | 18 | 123496 | 21536 | 29429477 |
Multiple congenital abnormalities | 43.03 | 11.59 | 27 | 123487 | 497 | 29450516 |
Encopresis | 42.84 | 11.59 | 18 | 123496 | 134 | 29450879 |
Cogwheel rigidity | 42.84 | 11.59 | 38 | 123476 | 1205 | 29449808 |
Mental status changes | 42.79 | 11.59 | 271 | 123243 | 34656 | 29416357 |
Pneumocystis jirovecii pneumonia | 42.62 | 11.59 | 9 | 123505 | 16770 | 29434243 |
Abdominal discomfort | 42.36 | 11.59 | 85 | 123429 | 47818 | 29403195 |
Cerebellar atrophy | 42.24 | 11.59 | 26 | 123488 | 462 | 29450551 |
COVID-19 | 42.16 | 11.59 | 53 | 123461 | 35961 | 29415052 |
Palmar-plantar erythrodysaesthesia syndrome | 41.67 | 11.59 | 6 | 123508 | 14753 | 29436260 |
Haemorrhage | 41.57 | 11.59 | 78 | 123436 | 44994 | 29406019 |
Blood prolactin increased | 41.52 | 11.59 | 41 | 123473 | 1493 | 29449520 |
Physical assault | 41.12 | 11.59 | 35 | 123479 | 1049 | 29449964 |
Confabulation | 40.99 | 11.59 | 17 | 123497 | 122 | 29450891 |
Choreoathetosis | 40.89 | 11.59 | 34 | 123480 | 986 | 29450027 |
Brugada syndrome | 40.43 | 11.59 | 29 | 123485 | 672 | 29450341 |
Respiratory failure | 40.33 | 11.59 | 239 | 123275 | 96892 | 29354121 |
Tooth malformation | 40.30 | 11.59 | 18 | 123496 | 158 | 29450855 |
Hyperprolactinaemia | 40.18 | 11.59 | 37 | 123477 | 1233 | 29449780 |
Delusion of grandeur | 40.18 | 11.59 | 24 | 123490 | 403 | 29450610 |
Anxiety | 40.03 | 11.59 | 538 | 122976 | 84827 | 29366186 |
Chorea | 39.95 | 11.59 | 33 | 123481 | 948 | 29450065 |
Apathy | 39.86 | 11.59 | 83 | 123431 | 6088 | 29444925 |
Nipple disorder | 39.82 | 11.59 | 18 | 123496 | 163 | 29450850 |
Acute myeloid leukaemia | 39.67 | 11.59 | 10 | 123504 | 16503 | 29434510 |
Pancreatitis acute | 39.60 | 11.59 | 204 | 123310 | 24181 | 29426832 |
Homicide | 39.43 | 11.59 | 32 | 123482 | 896 | 29450117 |
Seizure cluster | 39.41 | 11.59 | 16 | 123498 | 108 | 29450905 |
Psoriatic arthropathy | 39.17 | 11.59 | 7 | 123507 | 14684 | 29436329 |
Cerebral atrophy | 39.17 | 11.59 | 65 | 123449 | 4007 | 29447006 |
Stomatitis | 39.05 | 11.59 | 59 | 123455 | 37054 | 29413959 |
Injection site pain | 38.77 | 11.59 | 47 | 123467 | 32399 | 29418614 |
Pancreatitis | 38.75 | 11.59 | 262 | 123252 | 34252 | 29416761 |
Colitis | 38.70 | 11.59 | 44 | 123470 | 31204 | 29419809 |
Executive dysfunction | 38.52 | 11.59 | 19 | 123495 | 213 | 29450800 |
Haematuria | 38.45 | 11.59 | 79 | 123435 | 44060 | 29406953 |
Neoplasm progression | 38.07 | 11.59 | 15 | 123499 | 18597 | 29432416 |
Anisometropia | 37.97 | 11.59 | 13 | 123501 | 50 | 29450963 |
Acidosis hyperchloraemic | 37.92 | 11.59 | 22 | 123492 | 349 | 29450664 |
Eosinophil count decreased | 37.79 | 11.59 | 34 | 123480 | 1099 | 29449914 |
Emotional disorder | 37.48 | 11.59 | 71 | 123443 | 4860 | 29446153 |
Logorrhoea | 37.43 | 11.59 | 47 | 123467 | 2241 | 29448772 |
Dyscalculia | 37.32 | 11.59 | 11 | 123503 | 22 | 29450991 |
Crying | 36.96 | 11.59 | 74 | 123440 | 5277 | 29445736 |
Congenital myopia | 36.81 | 11.59 | 13 | 123501 | 56 | 29450957 |
Flushing | 36.81 | 11.59 | 40 | 123474 | 28952 | 29422061 |
Delusional disorder, unspecified type | 36.76 | 11.59 | 27 | 123487 | 650 | 29450363 |
Posture abnormal | 36.75 | 11.59 | 43 | 123471 | 1904 | 29449109 |
Oedema | 36.51 | 11.59 | 71 | 123443 | 40412 | 29410601 |
International normalised ratio increased | 36.50 | 11.59 | 82 | 123432 | 44290 | 29406723 |
Staphylococcal infection | 36.40 | 11.59 | 41 | 123473 | 29199 | 29421814 |
Haemoglobin decreased | 36.37 | 11.59 | 284 | 123230 | 108091 | 29342922 |
Lung disorder | 36.26 | 11.59 | 44 | 123470 | 30318 | 29420695 |
Tumour lysis syndrome | 36.20 | 11.59 | 7 | 123507 | 13877 | 29437136 |
Autonomic nervous system imbalance | 36.03 | 11.59 | 47 | 123467 | 2329 | 29448684 |
Infantile spasms | 35.98 | 11.59 | 17 | 123497 | 172 | 29450841 |
Full blood count decreased | 35.96 | 11.59 | 11 | 123503 | 15981 | 29435032 |
Carnitine decreased | 35.86 | 11.59 | 8 | 123506 | 0 | 29451013 |
Transient ischaemic attack | 35.62 | 11.59 | 27 | 123487 | 23243 | 29427770 |
Bacteraemia | 35.34 | 11.59 | 12 | 123502 | 16311 | 29434702 |
Angioedema | 35.28 | 11.59 | 49 | 123465 | 31866 | 29419147 |
Emotional disorder of childhood | 35.23 | 11.59 | 11 | 123503 | 29 | 29450984 |
Necrosis ischaemic | 35.13 | 11.59 | 18 | 123496 | 220 | 29450793 |
Dysgeusia | 35.11 | 11.59 | 26 | 123488 | 22648 | 29428365 |
Cellulitis | 35.09 | 11.59 | 88 | 123426 | 45752 | 29405261 |
Faecaloma | 35.08 | 11.59 | 63 | 123451 | 4139 | 29446874 |
Bronchiolitis | 34.97 | 11.59 | 50 | 123464 | 2705 | 29448308 |
Renal disorder | 34.87 | 11.59 | 26 | 123488 | 22569 | 29428444 |
Osteoarthritis | 34.77 | 11.59 | 16 | 123498 | 18087 | 29432926 |
Monocyte count increased | 34.69 | 11.59 | 60 | 123454 | 3826 | 29447187 |
Intelligence test abnormal | 34.60 | 11.59 | 10 | 123504 | 18 | 29450995 |
Synovitis | 34.33 | 11.59 | 3 | 123511 | 10887 | 29440126 |
Apraxia | 34.26 | 11.59 | 33 | 123481 | 1165 | 29449848 |
Heart disease congenital | 34.25 | 11.59 | 34 | 123480 | 1246 | 29449767 |
Anaphylactic shock | 34.19 | 11.59 | 7 | 123507 | 13329 | 29437684 |
Inappropriate antidiuretic hormone secretion | 34.18 | 11.59 | 112 | 123402 | 10820 | 29440193 |
Distractibility | 33.80 | 11.59 | 19 | 123495 | 283 | 29450730 |
Flight of ideas | 33.79 | 11.59 | 20 | 123494 | 330 | 29450683 |
Sexually inappropriate behaviour | 33.73 | 11.59 | 21 | 123493 | 381 | 29450632 |
Dysmetria | 33.73 | 11.59 | 21 | 123493 | 381 | 29450632 |
Pneumothorax | 33.69 | 11.59 | 12 | 123502 | 15830 | 29435183 |
Congenital astigmatism | 33.60 | 11.59 | 10 | 123504 | 21 | 29450992 |
Social (pragmatic) communication disorder | 33.58 | 11.59 | 13 | 123501 | 76 | 29450937 |
Product dose omission issue | 33.55 | 11.59 | 250 | 123264 | 96133 | 29354880 |
Laboratory test abnormal | 33.52 | 11.59 | 17 | 123497 | 18168 | 29432845 |
Arachnodactyly | 33.33 | 11.59 | 8 | 123506 | 3 | 29451010 |
Congenital nail disorder | 33.26 | 11.59 | 11 | 123503 | 37 | 29450976 |
Psychiatric decompensation | 33.14 | 11.59 | 36 | 123478 | 1468 | 29449545 |
Gastrointestinal malformation | 33.03 | 11.59 | 11 | 123503 | 38 | 29450975 |
Coloboma | 32.98 | 11.59 | 15 | 123499 | 138 | 29450875 |
Torticollis | 32.90 | 11.59 | 31 | 123483 | 1064 | 29449949 |
Bone pain | 32.90 | 11.59 | 18 | 123496 | 18434 | 29432579 |
Mood altered | 32.81 | 11.59 | 91 | 123423 | 8020 | 29442993 |
Hypotension | 32.73 | 11.59 | 593 | 122921 | 193761 | 29257252 |
Bronchopulmonary aspergillosis | 32.66 | 11.59 | 6 | 123508 | 12338 | 29438675 |
Pleurothotonus | 32.37 | 11.59 | 30 | 123484 | 1008 | 29450005 |
Growth retardation | 32.34 | 11.59 | 37 | 123477 | 1599 | 29449414 |
Atrial flutter | 32.26 | 11.59 | 9 | 123505 | 13885 | 29437128 |
Deep vein thrombosis | 32.09 | 11.59 | 127 | 123387 | 57272 | 29393741 |
Heart rate decreased | 32.04 | 11.59 | 34 | 123480 | 24878 | 29426135 |
Illiteracy | 32.00 | 11.59 | 8 | 123506 | 5 | 29451008 |
Postictal paralysis | 31.93 | 11.59 | 17 | 123497 | 226 | 29450787 |
Soliloquy | 31.79 | 11.59 | 20 | 123494 | 370 | 29450643 |
Anion gap increased | 31.68 | 11.59 | 36 | 123478 | 1544 | 29449469 |
Pharyngeal disorder | 31.45 | 11.59 | 24 | 123490 | 613 | 29450400 |
Toe walking | 31.38 | 11.59 | 7 | 123507 | 0 | 29451013 |
Nasal septum disorder | 31.22 | 11.59 | 11 | 123503 | 47 | 29450966 |
Inguinal hernia | 31.08 | 11.59 | 79 | 123435 | 6609 | 29444404 |
Retinal coloboma | 30.87 | 11.59 | 9 | 123505 | 17 | 29450996 |
Paradoxical drug reaction | 30.84 | 11.59 | 47 | 123467 | 2694 | 29448319 |
Acute coronary syndrome | 30.52 | 11.59 | 7 | 123507 | 12318 | 29438695 |
Perseveration | 30.47 | 11.59 | 13 | 123501 | 101 | 29450912 |
Postictal state | 30.36 | 11.59 | 25 | 123489 | 715 | 29450298 |
Middle insomnia | 30.34 | 11.59 | 71 | 123443 | 5637 | 29445376 |
Congenital knee deformity | 30.14 | 11.59 | 13 | 123501 | 104 | 29450909 |
Gross motor delay | 30.02 | 11.59 | 17 | 123497 | 257 | 29450756 |
Otitis media | 29.99 | 11.59 | 45 | 123469 | 2544 | 29448469 |
Intentional product use issue | 29.94 | 11.59 | 85 | 123429 | 42413 | 29408600 |
Decreased appetite | 29.94 | 11.59 | 427 | 123087 | 144915 | 29306098 |
Drug intolerance | 29.69 | 11.59 | 103 | 123411 | 48276 | 29402737 |
Drop attacks | 29.69 | 11.59 | 22 | 123492 | 537 | 29450476 |
Dyslipidaemia | 29.64 | 11.59 | 73 | 123441 | 5988 | 29445025 |
Pulmonary fibrosis | 29.58 | 11.59 | 14 | 123500 | 15568 | 29435445 |
Prognathism | 29.42 | 11.59 | 13 | 123501 | 111 | 29450902 |
Hypokalaemia | 29.40 | 11.59 | 109 | 123405 | 50094 | 29400919 |
Angina unstable | 29.36 | 11.59 | 5 | 123509 | 10860 | 29440153 |
Muscle tone disorder | 29.34 | 11.59 | 14 | 123500 | 145 | 29450868 |
Blood pressure fluctuation | 29.30 | 11.59 | 24 | 123490 | 19870 | 29431143 |
Rhinorrhoea | 29.23 | 11.59 | 28 | 123486 | 21491 | 29429522 |
Amblyopia | 29.20 | 11.59 | 11 | 123503 | 59 | 29450954 |
Hepatic adenoma | 29.10 | 11.59 | 10 | 123504 | 39 | 29450974 |
Developmental hip dysplasia | 29.07 | 11.59 | 17 | 123497 | 274 | 29450739 |
Night sweats | 28.99 | 11.59 | 13 | 123501 | 14919 | 29436094 |
Coma scale abnormal | 28.95 | 11.59 | 52 | 123462 | 3417 | 29447596 |
Sluggishness | 28.88 | 11.59 | 48 | 123466 | 2963 | 29448050 |
Affective disorder | 28.87 | 11.59 | 49 | 123465 | 3077 | 29447936 |
Medication error | 28.78 | 11.59 | 169 | 123345 | 21042 | 29429971 |
Neural tube defect | 28.70 | 11.59 | 10 | 123504 | 41 | 29450972 |
Limb hypoplasia congenital | 28.58 | 11.59 | 8 | 123506 | 12 | 29451001 |
Pyrexia | 28.34 | 11.59 | 951 | 122563 | 286671 | 29164342 |
Antisocial behaviour | 28.12 | 11.59 | 17 | 123497 | 292 | 29450721 |
Myelodysplastic syndrome | 28.08 | 11.59 | 20 | 123494 | 17774 | 29433239 |
Cerebral palsy | 28.04 | 11.59 | 12 | 123502 | 94 | 29450919 |
Inappropriate affect | 27.94 | 11.59 | 21 | 123493 | 524 | 29450489 |
Depressive symptom | 27.66 | 11.59 | 35 | 123479 | 1682 | 29449331 |
Balance disorder | 27.55 | 11.59 | 251 | 123263 | 35919 | 29415094 |
Drug hypersensitivity | 27.50 | 11.59 | 170 | 123344 | 68236 | 29382777 |
Pelvic deformity | 27.47 | 11.59 | 8 | 123506 | 15 | 29450998 |
Lymphocyte count increased | 27.41 | 11.59 | 45 | 123469 | 2749 | 29448264 |
Frustration tolerance decreased | 27.31 | 11.59 | 40 | 123474 | 2212 | 29448801 |
Meningocele | 27.27 | 11.59 | 9 | 123505 | 30 | 29450983 |
Anticonvulsant drug level abnormal | 27.27 | 11.59 | 9 | 123505 | 30 | 29450983 |
Convulsive threshold lowered | 27.17 | 11.59 | 20 | 123494 | 483 | 29450530 |
Intensive care unit acquired weakness | 27.01 | 11.59 | 26 | 123488 | 917 | 29450096 |
Retrognathia | 26.92 | 11.59 | 16 | 123498 | 266 | 29450747 |
Nephrolithiasis | 26.91 | 11.59 | 40 | 123474 | 25294 | 29425719 |
Social problem | 26.90 | 11.59 | 24 | 123490 | 767 | 29450246 |
Factor XIII deficiency | 26.90 | 11.59 | 6 | 123508 | 0 | 29451013 |
Mutism | 26.89 | 11.59 | 23 | 123491 | 694 | 29450319 |
Nasopharyngitis | 26.82 | 11.59 | 143 | 123371 | 59522 | 29391491 |
Visuospatial deficit | 26.76 | 11.59 | 11 | 123503 | 77 | 29450936 |
Neoplasm malignant | 26.73 | 11.59 | 19 | 123495 | 16906 | 29434107 |
Hypotelorism of orbit | 26.71 | 11.59 | 12 | 123502 | 107 | 29450906 |
Abdominal distension | 26.68 | 11.59 | 100 | 123414 | 45811 | 29405202 |
Cleft palate | 26.65 | 11.59 | 21 | 123493 | 563 | 29450450 |
Phobia | 26.49 | 11.59 | 13 | 123501 | 144 | 29450869 |
Head titubation | 26.46 | 11.59 | 16 | 123498 | 275 | 29450738 |
Deformity thorax | 26.41 | 11.59 | 9 | 123505 | 34 | 29450979 |
Brain malformation | 26.23 | 11.59 | 12 | 123502 | 112 | 29450901 |
Scaphocephaly | 26.21 | 11.59 | 8 | 123506 | 19 | 29450994 |
Speech sound disorder | 26.18 | 11.59 | 13 | 123501 | 148 | 29450865 |
Chronic obstructive pulmonary disease | 25.94 | 11.59 | 86 | 123428 | 40869 | 29410144 |
Hot flush | 25.80 | 11.59 | 15 | 123499 | 14855 | 29436158 |
Angular cheilitis | 25.80 | 11.59 | 13 | 123501 | 153 | 29450860 |
Infection | 25.79 | 11.59 | 201 | 123313 | 76550 | 29374463 |
Blood potassium decreased | 25.74 | 11.59 | 17 | 123497 | 15717 | 29435296 |
Duodenal ulcer | 25.52 | 11.59 | 4 | 123510 | 9234 | 29441779 |
Device related infection | 25.43 | 11.59 | 17 | 123497 | 15619 | 29435394 |
Aminoaciduria | 25.35 | 11.59 | 12 | 123502 | 122 | 29450891 |
Tonic clonic movements | 25.32 | 11.59 | 25 | 123489 | 910 | 29450103 |
Staring | 25.27 | 11.59 | 30 | 123484 | 1349 | 29449664 |
Oligoasthenozoospermia | 25.21 | 11.59 | 7 | 123507 | 10 | 29451003 |
Choking | 25.12 | 11.59 | 57 | 123457 | 4434 | 29446579 |
Bicuspid aortic valve | 25.11 | 11.59 | 14 | 123500 | 205 | 29450808 |
Negativism | 25.11 | 11.59 | 17 | 123497 | 358 | 29450655 |
Rash pruritic | 25.05 | 11.59 | 34 | 123480 | 22329 | 29428684 |
Osteomyelitis | 24.99 | 11.59 | 13 | 123501 | 13696 | 29437317 |
Dacryostenosis congenital | 24.91 | 11.59 | 9 | 123505 | 42 | 29450971 |
Clostridium difficile colitis | 24.88 | 11.59 | 12 | 123502 | 13200 | 29437813 |
Strabismus congenital | 24.87 | 11.59 | 8 | 123506 | 24 | 29450989 |
Unresponsive to stimuli | 24.86 | 11.59 | 185 | 123329 | 24941 | 29426072 |
Renal injury | 24.85 | 11.59 | 6 | 123508 | 10196 | 29440817 |
Hypervolaemia | 24.82 | 11.59 | 22 | 123492 | 17523 | 29433490 |
Foetal growth restriction | 24.73 | 11.59 | 51 | 123463 | 3715 | 29447298 |
Patient isolation | 24.63 | 11.59 | 8 | 123506 | 25 | 29450988 |
Post-injection delirium sedation syndrome | 24.55 | 11.59 | 18 | 123496 | 432 | 29450581 |
Acute hepatic failure | 24.52 | 11.59 | 107 | 123407 | 11845 | 29439168 |
Microstomia | 24.48 | 11.59 | 6 | 123508 | 3 | 29451010 |
Choroidal coloboma | 24.48 | 11.59 | 6 | 123508 | 3 | 29451010 |
COVID-19 pneumonia | 24.40 | 11.59 | 5 | 123509 | 9517 | 29441496 |
Eosinophil count increased | 24.40 | 11.59 | 77 | 123437 | 7292 | 29443721 |
Constipation | 24.34 | 11.59 | 333 | 123181 | 113827 | 29337186 |
Tic | 24.32 | 11.59 | 34 | 123480 | 1801 | 29449212 |
Judgement impaired | 24.28 | 11.59 | 20 | 123494 | 572 | 29450441 |
Food interaction | 24.26 | 11.59 | 24 | 123490 | 876 | 29450137 |
Anomaly of external ear congenital | 24.20 | 11.59 | 11 | 123503 | 101 | 29450912 |
Gout | 24.17 | 11.59 | 21 | 123493 | 16890 | 29434123 |
Renal tubular necrosis | 24.05 | 11.59 | 15 | 123499 | 14300 | 29436713 |
Inflammation | 24.03 | 11.59 | 36 | 123478 | 22692 | 29428321 |
Hallucination, visual | 23.95 | 11.59 | 125 | 123389 | 14890 | 29436123 |
Overweight | 23.93 | 11.59 | 30 | 123484 | 1428 | 29449585 |
Hypertension | 23.86 | 11.59 | 343 | 123171 | 116271 | 29334742 |
Faeces discoloured | 23.84 | 11.59 | 13 | 123501 | 13338 | 29437675 |
Selective eating disorder | 23.83 | 11.59 | 32 | 123482 | 1631 | 29449382 |
Water intoxication | 23.77 | 11.59 | 17 | 123497 | 392 | 29450621 |
Metastases to bone | 23.76 | 11.59 | 6 | 123508 | 9892 | 29441121 |
Metabolic syndrome | 23.69 | 11.59 | 30 | 123484 | 1443 | 29449570 |
Ventricular tachycardia | 23.63 | 11.59 | 36 | 123478 | 22538 | 29428475 |
Metabolic acidosis | 23.63 | 11.59 | 251 | 123263 | 37411 | 29413602 |
Congenital scoliosis | 23.63 | 11.59 | 10 | 123504 | 76 | 29450937 |
Dry skin | 23.61 | 11.59 | 38 | 123476 | 23269 | 29427744 |
Urinary tract infection | 23.61 | 11.59 | 191 | 123323 | 72163 | 29378850 |
Condition aggravated | 23.60 | 11.59 | 788 | 122726 | 145507 | 29305506 |
Impaired reasoning | 23.57 | 11.59 | 11 | 123503 | 108 | 29450905 |
Cerebral haemorrhage | 23.53 | 11.59 | 61 | 123453 | 31365 | 29419648 |
Neuralgia | 23.53 | 11.59 | 8 | 123506 | 10866 | 29440147 |
Oropharyngeal discomfort | 23.52 | 11.59 | 40 | 123474 | 2516 | 29448497 |
Hyponatraemia | 23.46 | 11.59 | 405 | 123109 | 67228 | 29383785 |
Aptyalism | 23.45 | 11.59 | 15 | 123499 | 286 | 29450727 |
Diabetic hyperosmolar coma | 23.38 | 11.59 | 16 | 123498 | 343 | 29450670 |
Cerebral infarction | 23.37 | 11.59 | 42 | 123472 | 24633 | 29426380 |
Carnitine deficiency | 23.34 | 11.59 | 9 | 123505 | 52 | 29450961 |
Drug level above therapeutic | 23.13 | 11.59 | 46 | 123468 | 3264 | 29447749 |
Pulmonary mass | 23.10 | 11.59 | 8 | 123506 | 10740 | 29440273 |
Cholestasis | 23.07 | 11.59 | 39 | 123475 | 23423 | 29427590 |
Muscular weakness | 23.01 | 11.59 | 158 | 123356 | 61894 | 29389119 |
Blood bilirubin increased | 22.99 | 11.59 | 69 | 123445 | 33824 | 29417189 |
Candida infection | 22.88 | 11.59 | 18 | 123496 | 15207 | 29435806 |
Blood lactic acid increased | 22.65 | 11.59 | 64 | 123450 | 5702 | 29445311 |
Grandiosity | 22.52 | 11.59 | 15 | 123499 | 307 | 29450706 |
Localised infection | 22.50 | 11.59 | 15 | 123499 | 13801 | 29437212 |
Patent ductus arteriosus | 22.47 | 11.59 | 44 | 123470 | 3087 | 29447926 |
Drug abuse | 22.42 | 11.59 | 463 | 123051 | 79420 | 29371593 |
Congenital neurological disorder | 22.41 | 11.59 | 5 | 123509 | 0 | 29451013 |
Meningomyelocele | 22.38 | 11.59 | 12 | 123502 | 162 | 29450851 |
Bone marrow failure | 22.35 | 11.59 | 51 | 123463 | 27398 | 29423615 |
Ventricular septal defect | 22.25 | 11.59 | 47 | 123467 | 3482 | 29447531 |
Pulmonary hypertension | 22.18 | 11.59 | 27 | 123487 | 18581 | 29432432 |
Failure to suspend medication | 22.11 | 11.59 | 16 | 123498 | 376 | 29450637 |
Congenital genital malformation | 21.99 | 11.59 | 10 | 123504 | 92 | 29450921 |
Incontinence | 21.90 | 11.59 | 58 | 123456 | 4974 | 29446039 |
Throat irritation | 21.73 | 11.59 | 5 | 123509 | 8780 | 29442233 |
Type 2 diabetes mellitus | 21.62 | 11.59 | 113 | 123401 | 13468 | 29437545 |
Wrong product administered | 21.55 | 11.59 | 54 | 123460 | 4477 | 29446536 |
Subacute endocarditis | 21.53 | 11.59 | 8 | 123506 | 41 | 29450972 |
Mood swings | 21.52 | 11.59 | 73 | 123441 | 7178 | 29443835 |
Salivary gland enlargement | 21.52 | 11.59 | 7 | 123507 | 22 | 29450991 |
Nephropathy toxic | 21.46 | 11.59 | 9 | 123505 | 10747 | 29440266 |
Congenital nipple anomaly | 21.44 | 11.59 | 6 | 123508 | 9 | 29451004 |
Frequent bowel movements | 21.42 | 11.59 | 6 | 123508 | 9233 | 29441780 |
Squamous cell carcinoma | 21.40 | 11.59 | 8 | 123506 | 10243 | 29440770 |
Blood osmolarity decreased | 21.38 | 11.59 | 18 | 123496 | 531 | 29450482 |
Hyperthermia | 21.35 | 11.59 | 87 | 123427 | 9343 | 29441670 |
Transplant rejection | 21.33 | 11.59 | 6 | 123508 | 9206 | 29441807 |
Blood triglycerides increased | 21.28 | 11.59 | 108 | 123406 | 12726 | 29438287 |
Feeling hot | 21.22 | 11.59 | 20 | 123494 | 15468 | 29435545 |
Decreased gait velocity | 21.15 | 11.59 | 11 | 123503 | 139 | 29450874 |
Head deformity | 21.09 | 11.59 | 9 | 123505 | 70 | 29450943 |
Adrenal insufficiency | 21.07 | 11.59 | 10 | 123504 | 11104 | 29439909 |
Conductive deafness | 21.01 | 11.59 | 11 | 123503 | 141 | 29450872 |
Self-injurious ideation | 20.95 | 11.59 | 29 | 123485 | 1522 | 29449491 |
Basilar artery occlusion | 20.87 | 11.59 | 9 | 123505 | 72 | 29450941 |
Refraction disorder | 20.84 | 11.59 | 7 | 123507 | 25 | 29450988 |
Flatulence | 20.79 | 11.59 | 26 | 123488 | 17683 | 29433330 |
Clostridium difficile infection | 20.78 | 11.59 | 22 | 123492 | 16119 | 29434894 |
Brachydactyly | 20.76 | 11.59 | 12 | 123502 | 189 | 29450824 |
Febrile bone marrow aplasia | 20.73 | 11.59 | 3 | 123511 | 7348 | 29443665 |
Shock haemorrhagic | 20.71 | 11.59 | 7 | 123507 | 9544 | 29441469 |
Micrognathia | 20.71 | 11.59 | 14 | 123500 | 294 | 29450719 |
Niemann-Pick disease | 20.69 | 11.59 | 6 | 123508 | 11 | 29451002 |
Epidermolysis bullosa | 20.68 | 11.59 | 10 | 123504 | 107 | 29450906 |
Cardiogenic shock | 20.68 | 11.59 | 30 | 123484 | 19160 | 29431853 |
Skin cancer | 20.59 | 11.59 | 5 | 123509 | 8463 | 29442550 |
Blood pressure systolic increased | 20.55 | 11.59 | 24 | 123490 | 16821 | 29434192 |
Movement disorder | 20.51 | 11.59 | 91 | 123423 | 10146 | 29440867 |
Squamous cell carcinoma of skin | 20.49 | 11.59 | 7 | 123507 | 9479 | 29441534 |
Haemangioma | 20.42 | 11.59 | 30 | 123484 | 1664 | 29449349 |
Intestinal ischaemia | 20.42 | 11.59 | 68 | 123446 | 6624 | 29444389 |
Impaired healing | 20.41 | 11.59 | 16 | 123498 | 13542 | 29437471 |
Madarosis | 20.38 | 11.59 | 12 | 123502 | 196 | 29450817 |
Ageusia | 20.36 | 11.59 | 6 | 123508 | 8932 | 29442081 |
Pleural effusion | 20.30 | 11.59 | 197 | 123317 | 71711 | 29379302 |
Delusional perception | 20.16 | 11.59 | 11 | 123503 | 154 | 29450859 |
Bronchopulmonary disease | 20.08 | 11.59 | 5 | 123509 | 3 | 29451010 |
Lacrimal gland enlargement | 20.08 | 11.59 | 5 | 123509 | 3 | 29451010 |
Gastric volvulus | 20.08 | 11.59 | 5 | 123509 | 3 | 29451010 |
Pneumonia bacterial | 20.00 | 11.59 | 7 | 123507 | 9336 | 29441677 |
Cardiac disorder | 19.85 | 11.59 | 84 | 123430 | 37179 | 29413834 |
Sensory integrative dysfunction | 19.85 | 11.59 | 7 | 123507 | 30 | 29450983 |
Dissociation | 19.77 | 11.59 | 24 | 123490 | 1105 | 29449908 |
Diverticulitis | 19.75 | 11.59 | 27 | 123487 | 17677 | 29433336 |
Hyperexplexia | 19.67 | 11.59 | 7 | 123507 | 31 | 29450982 |
Blood glucose increased | 19.56 | 11.59 | 155 | 123359 | 58829 | 29392184 |
Febrile convulsion | 19.46 | 11.59 | 17 | 123497 | 528 | 29450485 |
Pasteurella infection | 19.44 | 11.59 | 6 | 123508 | 15 | 29450998 |
Gingival hypertrophy | 19.37 | 11.59 | 29 | 123485 | 1636 | 29449377 |
Brachycephaly | 19.34 | 11.59 | 8 | 123506 | 57 | 29450956 |
Graft versus host disease | 19.30 | 11.59 | 8 | 123506 | 9620 | 29441393 |
Aspiration | 19.28 | 11.59 | 89 | 123425 | 10091 | 29440922 |
Poverty of speech | 19.17 | 11.59 | 12 | 123502 | 220 | 29450793 |
Brain stem auditory evoked response abnormal | 19.17 | 11.59 | 6 | 123508 | 16 | 29450997 |
Verbal abuse | 19.16 | 11.59 | 11 | 123503 | 171 | 29450842 |
Depressed mood | 19.14 | 11.59 | 126 | 123388 | 16322 | 29434691 |
Metastases to liver | 19.14 | 11.59 | 13 | 123501 | 11843 | 29439170 |
Tachycardia | 19.13 | 11.59 | 416 | 123098 | 71994 | 29379019 |
Mucosal ulceration | 19.12 | 11.59 | 21 | 123493 | 867 | 29450146 |
Limb discomfort | 19.10 | 11.59 | 8 | 123506 | 9560 | 29441453 |
Venoocclusive liver disease | 19.10 | 11.59 | 3 | 123511 | 6914 | 29444099 |
Trismus | 19.07 | 11.59 | 35 | 123479 | 2338 | 29448675 |
Type 1 diabetes mellitus | 19.01 | 11.59 | 45 | 123469 | 3599 | 29447414 |
Ehlers-Danlos syndrome | 18.98 | 11.59 | 7 | 123507 | 35 | 29450978 |
Developmental regression | 18.98 | 11.59 | 7 | 123507 | 35 | 29450978 |
Kyphosis congenital | 18.97 | 11.59 | 5 | 123509 | 5 | 29451008 |
Energy increased | 18.96 | 11.59 | 24 | 123490 | 1154 | 29449859 |
Myelosuppression | 18.95 | 11.59 | 14 | 123500 | 12213 | 29438800 |
Myoglobinuria | 18.95 | 11.59 | 19 | 123495 | 705 | 29450308 |
Hypoxia | 18.90 | 11.59 | 118 | 123396 | 47261 | 29403752 |
Supernumerary nipple | 18.82 | 11.59 | 7 | 123507 | 36 | 29450977 |
Hostility | 18.78 | 11.59 | 20 | 123494 | 797 | 29450216 |
Mydriasis | 18.71 | 11.59 | 62 | 123452 | 6023 | 29444990 |
Hepatitis C virus test positive | 18.71 | 11.59 | 13 | 123501 | 286 | 29450727 |
Sarcopenia | 18.67 | 11.59 | 14 | 123500 | 348 | 29450665 |
Lennox-Gastaut syndrome | 18.66 | 11.59 | 7 | 123507 | 37 | 29450976 |
IVth nerve disorder | 18.65 | 11.59 | 6 | 123508 | 18 | 29450995 |
Injection site swelling | 18.59 | 11.59 | 8 | 123506 | 9409 | 29441604 |
Contusion | 18.54 | 11.59 | 67 | 123447 | 31028 | 29419985 |
Haemorrhoids | 18.52 | 11.59 | 13 | 123501 | 11644 | 29439369 |
Presyncope | 18.49 | 11.59 | 24 | 123490 | 16065 | 29434948 |
Pain in jaw | 18.48 | 11.59 | 13 | 123501 | 11628 | 29439385 |
Iris coloboma | 18.41 | 11.59 | 6 | 123508 | 19 | 29450994 |
Suspiciousness | 18.40 | 11.59 | 13 | 123501 | 294 | 29450719 |
Cholelithiasis | 18.39 | 11.59 | 31 | 123483 | 18641 | 29432372 |
Lymphoma | 18.39 | 11.59 | 9 | 123505 | 9819 | 29441194 |
Ammonia abnormal | 18.34 | 11.59 | 8 | 123506 | 66 | 29450947 |
Pulmonary oedema | 18.33 | 11.59 | 104 | 123410 | 42631 | 29408382 |
Gastric ulcer | 18.29 | 11.59 | 19 | 123495 | 14042 | 29436971 |
Gastric disorder | 18.29 | 11.59 | 11 | 123503 | 10693 | 29440320 |
Heterophoria | 18.24 | 11.59 | 8 | 123506 | 67 | 29450946 |
Aphasia | 18.23 | 11.59 | 140 | 123374 | 19058 | 29431955 |
Enterocolitis | 18.16 | 11.59 | 3 | 123511 | 6663 | 29444350 |
Toxic epidermal necrolysis | 18.15 | 11.59 | 134 | 123380 | 18019 | 29432994 |
Partial seizures with secondary generalisation | 18.13 | 11.59 | 12 | 123502 | 243 | 29450770 |
Tonsillitis | 18.07 | 11.59 | 31 | 123483 | 1964 | 29449049 |
Psychomotor disadaptation syndrome | 18.06 | 11.59 | 5 | 123509 | 7 | 29451006 |
Agranulocytosis | 18.03 | 11.59 | 146 | 123368 | 20194 | 29430819 |
Sperm concentration decreased | 18.02 | 11.59 | 10 | 123504 | 145 | 29450868 |
Injection site erythema | 17.99 | 11.59 | 19 | 123495 | 13937 | 29437076 |
Poor sucking reflex | 17.95 | 11.59 | 13 | 123501 | 306 | 29450707 |
Retracted nipple | 17.93 | 11.59 | 4 | 123510 | 0 | 29451013 |
Ear, nose and throat examination abnormal | 17.93 | 11.59 | 4 | 123510 | 0 | 29451013 |
Laryngeal web | 17.93 | 11.59 | 4 | 123510 | 0 | 29451013 |
Dentofacial anomaly | 17.93 | 11.59 | 4 | 123510 | 0 | 29451013 |
Phimosis | 17.92 | 11.59 | 18 | 123496 | 669 | 29450344 |
Skin ulcer | 17.90 | 11.59 | 32 | 123482 | 18808 | 29432205 |
Cataract | 17.88 | 11.59 | 42 | 123472 | 22336 | 29428677 |
Syndactyly | 17.87 | 11.59 | 19 | 123495 | 756 | 29450257 |
Lower gastrointestinal haemorrhage | 17.84 | 11.59 | 6 | 123508 | 8207 | 29442806 |
Hallucination | 17.83 | 11.59 | 274 | 123240 | 44438 | 29406575 |
Aura | 17.77 | 11.59 | 13 | 123501 | 311 | 29450702 |
Coma blister | 17.74 | 11.59 | 8 | 123506 | 72 | 29450941 |
Adenoidectomy | 17.71 | 11.59 | 9 | 123505 | 108 | 29450905 |
Retinogram abnormal | 17.71 | 11.59 | 9 | 123505 | 108 | 29450905 |
Conjunctival hyperaemia | 17.70 | 11.59 | 32 | 123482 | 2113 | 29448900 |
C-reactive protein abnormal | 17.68 | 11.59 | 3 | 123511 | 6533 | 29444480 |
Resting tremor | 17.65 | 11.59 | 17 | 123497 | 600 | 29450413 |
Congenital inguinal hernia | 17.55 | 11.59 | 10 | 123504 | 153 | 29450860 |
Jaundice | 17.55 | 11.59 | 63 | 123451 | 29233 | 29421780 |
Tachyphrenia | 17.53 | 11.59 | 23 | 123491 | 1146 | 29449867 |
Hyperhomocysteinaemia | 17.51 | 11.59 | 11 | 123503 | 203 | 29450810 |
Product administered to patient of inappropriate age | 17.49 | 11.59 | 36 | 123478 | 2619 | 29448394 |
Neutropenic sepsis | 17.45 | 11.59 | 14 | 123500 | 11713 | 29439300 |
Miosis | 17.43 | 11.59 | 73 | 123441 | 7936 | 29443077 |
Simple partial seizures | 17.43 | 11.59 | 12 | 123502 | 260 | 29450753 |
Body dysmorphic disorder | 17.42 | 11.59 | 9 | 123505 | 112 | 29450901 |
Hypokinesia | 17.34 | 11.59 | 70 | 123444 | 7484 | 29443529 |
School refusal | 17.34 | 11.59 | 6 | 123508 | 24 | 29450989 |
Compensatory sweating | 17.34 | 11.59 | 6 | 123508 | 24 | 29450989 |
Hyperdynamic left ventricle | 17.28 | 11.59 | 9 | 123505 | 114 | 29450899 |
Withdrawal syndrome | 17.18 | 11.59 | 91 | 123423 | 10901 | 29440112 |
Dementia with Lewy bodies | 17.17 | 11.59 | 17 | 123497 | 621 | 29450392 |
Hyporeflexia | 17.11 | 11.59 | 29 | 123485 | 1819 | 29449194 |
Injection site reaction | 17.10 | 11.59 | 13 | 123501 | 11175 | 29439838 |
Kyphosis | 17.02 | 11.59 | 22 | 123492 | 1080 | 29449933 |
Oral candidiasis | 16.98 | 11.59 | 12 | 123502 | 10710 | 29440303 |
Tendonitis | 16.98 | 11.59 | 6 | 123508 | 7955 | 29443058 |
Necrotising colitis | 16.96 | 11.59 | 21 | 123493 | 987 | 29450026 |
Skin exfoliation | 16.92 | 11.59 | 44 | 123470 | 22601 | 29428412 |
Rhabdomyolysis | 16.91 | 11.59 | 352 | 123162 | 60456 | 29390557 |
Conversion disorder | 16.91 | 11.59 | 13 | 123501 | 336 | 29450677 |
Excessive masturbation | 16.76 | 11.59 | 8 | 123506 | 83 | 29450930 |
Thought blocking | 16.75 | 11.59 | 9 | 123505 | 122 | 29450891 |
Diffuse large B-cell lymphoma | 16.71 | 11.59 | 3 | 123511 | 6273 | 29444740 |
Craniofacial deformity | 16.67 | 11.59 | 8 | 123506 | 84 | 29450929 |
Incoherent | 16.64 | 11.59 | 46 | 123468 | 4046 | 29446967 |
Dyspepsia | 16.61 | 11.59 | 67 | 123447 | 30058 | 29420955 |
Muscle twitching | 16.57 | 11.59 | 72 | 123442 | 7954 | 29443059 |
Eating disorder | 16.51 | 11.59 | 67 | 123447 | 7180 | 29443833 |
Ankyloglossia congenital | 16.48 | 11.59 | 12 | 123502 | 285 | 29450728 |
Immune reconstitution inflammatory syndrome | 16.43 | 11.59 | 6 | 123508 | 7796 | 29443217 |
Dermatitis | 16.42 | 11.59 | 6 | 123508 | 7792 | 29443221 |
Coronary artery occlusion | 16.38 | 11.59 | 11 | 123503 | 10083 | 29440930 |
Kidney malformation | 16.23 | 11.59 | 10 | 123504 | 178 | 29450835 |
Polydipsia | 16.17 | 11.59 | 41 | 123473 | 3424 | 29447589 |
Postural tremor | 16.08 | 11.59 | 12 | 123502 | 296 | 29450717 |
Maternal drugs affecting foetus | 16.07 | 11.59 | 44 | 123470 | 3849 | 29447164 |
Neutrophil Pelger-Huet anomaly present | 16.03 | 11.59 | 11 | 123503 | 237 | 29450776 |
Chromaturia | 15.88 | 11.59 | 18 | 123496 | 12784 | 29438229 |
Erectile dysfunction | 15.82 | 11.59 | 129 | 123385 | 17880 | 29433133 |
Irregular sleep phase | 15.82 | 11.59 | 7 | 123507 | 60 | 29450953 |
Congenital cerebral cyst | 15.80 | 11.59 | 5 | 123509 | 14 | 29450999 |
Epileptic aura | 15.80 | 11.59 | 5 | 123509 | 14 | 29450999 |
Vasoplegia syndrome | 15.77 | 11.59 | 25 | 123489 | 1483 | 29449530 |
Neurological decompensation | 15.77 | 11.59 | 33 | 123481 | 2429 | 29448584 |
Automatism | 15.74 | 11.59 | 8 | 123506 | 96 | 29450917 |
Reduced facial expression | 15.73 | 11.59 | 17 | 123497 | 689 | 29450324 |
Throat tightness | 15.72 | 11.59 | 5 | 123509 | 7086 | 29443927 |
Separation anxiety disorder | 15.70 | 11.59 | 4 | 123510 | 3 | 29451010 |
Congenital jaw malformation | 15.70 | 11.59 | 4 | 123510 | 3 | 29451010 |
Hyperglycinaemia | 15.70 | 11.59 | 4 | 123510 | 3 | 29451010 |
Joint hyperextension | 15.60 | 11.59 | 8 | 123506 | 98 | 29450915 |
Pancreatitis haemorrhagic | 15.54 | 11.59 | 12 | 123502 | 312 | 29450701 |
Therapeutic response changed | 15.51 | 11.59 | 12 | 123502 | 313 | 29450700 |
Schizoaffective disorder bipolar type | 15.51 | 11.59 | 6 | 123508 | 35 | 29450978 |
Otitis media acute | 15.49 | 11.59 | 14 | 123500 | 455 | 29450558 |
Peripheral sensory neuropathy | 15.47 | 11.59 | 3 | 123511 | 5936 | 29445077 |
Myocardial ischaemia | 15.43 | 11.59 | 27 | 123487 | 16001 | 29435012 |
Cardiac failure chronic | 15.37 | 11.59 | 4 | 123510 | 6463 | 29444550 |
Delayed fontanelle closure | 15.37 | 11.59 | 6 | 123508 | 36 | 29450977 |
Circadian rhythm sleep disorder | 15.34 | 11.59 | 13 | 123501 | 387 | 29450626 |
Blood urine present | 15.34 | 11.59 | 11 | 123503 | 9744 | 29441269 |
Hyperreflexia | 15.30 | 11.59 | 35 | 123479 | 2737 | 29448276 |
Opsoclonus myoclonus | 15.24 | 11.59 | 7 | 123507 | 66 | 29450947 |
Pulmonary arterial hypertension | 15.24 | 11.59 | 6 | 123508 | 7443 | 29443570 |
Diarrhoea haemorrhagic | 15.23 | 11.59 | 3 | 123511 | 5871 | 29445142 |
Intermittent explosive disorder | 15.17 | 11.59 | 4 | 123510 | 4 | 29451009 |
Drug resistance | 15.16 | 11.59 | 147 | 123367 | 21393 | 29429620 |
Myopathy | 15.15 | 11.59 | 13 | 123501 | 10520 | 29440493 |
Auditory disorder | 15.11 | 11.59 | 11 | 123503 | 261 | 29450752 |
Epileptic psychosis | 15.08 | 11.59 | 5 | 123509 | 17 | 29450996 |
Abnormal labour affecting foetus | 15.08 | 11.59 | 5 | 123509 | 17 | 29450996 |
Rebound psychosis | 15.07 | 11.59 | 9 | 123505 | 151 | 29450862 |
Embolism | 15.05 | 11.59 | 5 | 123509 | 6891 | 29444122 |
Poor quality sleep | 15.02 | 11.59 | 65 | 123449 | 7168 | 29443845 |
Metastases to lung | 15.00 | 11.59 | 7 | 123507 | 7848 | 29443165 |
Nephrogenic diabetes insipidus | 14.94 | 11.59 | 21 | 123493 | 1118 | 29449895 |
Cardiac failure acute | 14.94 | 11.59 | 10 | 123504 | 9182 | 29441831 |
Oral mucosa erosion | 14.93 | 11.59 | 18 | 123496 | 823 | 29450190 |
Abnormal palmar/plantar creases | 14.92 | 11.59 | 10 | 123504 | 207 | 29450806 |
Wound | 14.92 | 11.59 | 17 | 123497 | 12046 | 29438967 |
Reproductive tract hypoplasia, male | 14.86 | 11.59 | 5 | 123509 | 18 | 29450995 |
Adverse drug reaction | 14.83 | 11.59 | 51 | 123463 | 23969 | 29427044 |
Contraindicated product administered | 14.82 | 11.59 | 34 | 123480 | 18232 | 29432781 |
Muscle contracture | 14.74 | 11.59 | 21 | 123493 | 1132 | 29449881 |
Camptocormia | 14.72 | 11.59 | 9 | 123505 | 158 | 29450855 |
Mouth breathing | 14.71 | 11.59 | 7 | 123507 | 72 | 29450941 |
Enteritis | 14.69 | 11.59 | 5 | 123509 | 6786 | 29444227 |
Clonic convulsion | 14.67 | 11.59 | 15 | 123499 | 570 | 29450443 |
Acute pulmonary oedema | 14.65 | 11.59 | 5 | 123509 | 6774 | 29444239 |
Heart rate irregular | 14.63 | 11.59 | 20 | 123494 | 13097 | 29437916 |
Use of accessory respiratory muscles | 14.61 | 11.59 | 12 | 123502 | 342 | 29450671 |
Screaming | 14.60 | 11.59 | 22 | 123492 | 1248 | 29449765 |
Hypomagnesaemia | 14.59 | 11.59 | 32 | 123482 | 17436 | 29433577 |
Wrist deformity | 14.55 | 11.59 | 12 | 123502 | 344 | 29450669 |
Haematoma | 14.52 | 11.59 | 49 | 123465 | 23163 | 29427850 |
Hyperthyroidism | 14.49 | 11.59 | 9 | 123505 | 8599 | 29442414 |
Feminisation acquired | 14.47 | 11.59 | 6 | 123508 | 43 | 29450970 |
Ischaemic stroke | 14.42 | 11.59 | 28 | 123486 | 15949 | 29435064 |
Echopraxia | 14.29 | 11.59 | 4 | 123510 | 6 | 29451007 |
Intestinal perforation | 14.25 | 11.59 | 8 | 123506 | 8078 | 29442935 |
Gender dysphoria | 14.24 | 11.59 | 6 | 123508 | 45 | 29450968 |
Hepatic cirrhosis | 14.21 | 11.59 | 24 | 123490 | 14420 | 29436593 |
Suspected suicide attempt | 14.18 | 11.59 | 8 | 123506 | 120 | 29450893 |
Fungal infection | 14.16 | 11.59 | 22 | 123492 | 13663 | 29437350 |
Hypovolaemia | 14.12 | 11.59 | 8 | 123506 | 8037 | 29442976 |
Gingival atrophy | 14.02 | 11.59 | 6 | 123508 | 47 | 29450966 |
Adenoidal hypertrophy | 14.01 | 11.59 | 8 | 123506 | 123 | 29450890 |
Dysphagia | 14.01 | 11.59 | 314 | 123200 | 54612 | 29396401 |
Feeding disorder | 13.98 | 11.59 | 55 | 123459 | 5812 | 29445201 |
Pulmonary thrombosis | 13.91 | 11.59 | 5 | 123509 | 6560 | 29444453 |
Hepatitis B | 13.85 | 11.59 | 3 | 123511 | 5494 | 29445519 |
Frontotemporal dementia | 13.82 | 11.59 | 10 | 123504 | 235 | 29450778 |
Anxiety disorder | 13.77 | 11.59 | 24 | 123490 | 1540 | 29449473 |
Drug ineffective for unapproved indication | 13.69 | 11.59 | 104 | 123410 | 14110 | 29436903 |
Pulmonary valve incompetence | 13.63 | 11.59 | 16 | 123498 | 711 | 29450302 |
Tympanic membrane disorder | 13.60 | 11.59 | 6 | 123508 | 51 | 29450962 |
SJS-TEN overlap | 13.57 | 11.59 | 10 | 123504 | 242 | 29450771 |
Sinus disorder | 13.56 | 11.59 | 4 | 123510 | 5951 | 29445062 |
Coprolalia | 13.56 | 11.59 | 5 | 123509 | 25 | 29450988 |
Small intestinal obstruction | 13.51 | 11.59 | 21 | 123493 | 13040 | 29437973 |
Electrocardiogram QT prolonged | 13.48 | 11.59 | 219 | 123295 | 35918 | 29415095 |
Sudden death | 13.45 | 11.59 | 103 | 123411 | 14007 | 29437006 |
Acquired epileptic aphasia | 13.45 | 11.59 | 3 | 123511 | 0 | 29451013 |
Mentally late developer | 13.45 | 11.59 | 3 | 123511 | 0 | 29451013 |
Congenital tongue anomaly | 13.45 | 11.59 | 3 | 123511 | 0 | 29451013 |
Renal fusion anomaly | 13.45 | 11.59 | 3 | 123511 | 0 | 29451013 |
Deformity of orbit | 13.45 | 11.59 | 3 | 123511 | 0 | 29451013 |
Dacryoadenitis acquired | 13.45 | 11.59 | 3 | 123511 | 0 | 29451013 |
Hypocarnitinaemia | 13.45 | 11.59 | 3 | 123511 | 0 | 29451013 |
Blindness congenital | 13.45 | 11.59 | 3 | 123511 | 0 | 29451013 |
Anuria | 13.45 | 11.59 | 12 | 123502 | 9529 | 29441484 |
Neonatal hypoacusis | 13.45 | 11.59 | 3 | 123511 | 0 | 29451013 |
Cerebral cyst | 13.43 | 11.59 | 10 | 123504 | 246 | 29450767 |
Limb asymmetry | 13.42 | 11.59 | 7 | 123507 | 89 | 29450924 |
Cardiac murmur | 13.41 | 11.59 | 59 | 123455 | 6554 | 29444459 |
Device issue | 13.28 | 11.59 | 8 | 123506 | 7772 | 29443241 |
Haemorrhagic stroke | 13.22 | 11.59 | 4 | 123510 | 5852 | 29445161 |
Mastication disorder | 13.20 | 11.59 | 20 | 123494 | 1140 | 29449873 |
Injection site pruritus | 13.19 | 11.59 | 4 | 123510 | 5845 | 29445168 |
Cytopenia | 13.19 | 11.59 | 13 | 123501 | 9846 | 29441167 |
Agitation neonatal | 13.16 | 11.59 | 19 | 123495 | 1037 | 29449976 |
Drug level fluctuating | 13.15 | 11.59 | 13 | 123501 | 474 | 29450539 |
Wheezing | 13.14 | 11.59 | 83 | 123431 | 33157 | 29417856 |
Accidental death | 13.11 | 11.59 | 28 | 123486 | 2090 | 29448923 |
Nephrotic syndrome | 13.11 | 11.59 | 5 | 123509 | 6323 | 29444690 |
CSF white blood cell count positive | 13.09 | 11.59 | 5 | 123509 | 28 | 29450985 |
Cytomegalovirus viraemia | 13.08 | 11.59 | 5 | 123509 | 6315 | 29444698 |
Snoring | 13.05 | 11.59 | 33 | 123481 | 2751 | 29448262 |
Gastritis | 13.04 | 11.59 | 40 | 123474 | 19477 | 29431536 |
Terminal insomnia | 13.03 | 11.59 | 12 | 123502 | 400 | 29450613 |
Hand-eye coordination impaired | 13.03 | 11.59 | 6 | 123508 | 57 | 29450956 |
Wrong schedule | 12.86 | 11.59 | 8 | 123506 | 145 | 29450868 |
Elbow deformity | 12.81 | 11.59 | 5 | 123509 | 30 | 29450983 |
Blood alkaline phosphatase increased | 12.80 | 11.59 | 68 | 123446 | 28338 | 29422675 |
Necrotising enterocolitis neonatal | 12.80 | 11.59 | 9 | 123505 | 202 | 29450811 |
Macrocephaly | 12.76 | 11.59 | 12 | 123502 | 411 | 29450602 |
Haematotoxicity | 12.74 | 11.59 | 6 | 123508 | 6693 | 29444320 |
Hip fracture | 12.74 | 11.59 | 15 | 123499 | 10477 | 29440536 |
Hypercalcaemia | 12.74 | 11.59 | 21 | 123493 | 12738 | 29438275 |
Diabetic coma | 12.72 | 11.59 | 16 | 123498 | 764 | 29450249 |
Pancreatic carcinoma | 12.71 | 11.59 | 7 | 123507 | 7143 | 29443870 |
Mixed delusion | 12.69 | 11.59 | 4 | 123510 | 11 | 29451002 |
Haemorrhage intracranial | 12.68 | 11.59 | 26 | 123488 | 14516 | 29436497 |
Skin disorder | 12.68 | 11.59 | 18 | 123496 | 11600 | 29439413 |
Wrong technique in product usage process | 12.67 | 11.59 | 78 | 123436 | 31350 | 29419663 |
Gallbladder disorder | 12.67 | 11.59 | 4 | 123510 | 5696 | 29445317 |
Disseminated intravascular coagulation | 12.62 | 11.59 | 42 | 123472 | 19938 | 29431075 |
Mass | 12.58 | 11.59 | 7 | 123507 | 7104 | 29443909 |
Base excess increased | 12.54 | 11.59 | 5 | 123509 | 32 | 29450981 |
Cholangitis | 12.52 | 11.59 | 8 | 123506 | 7529 | 29443484 |
Poisoning | 12.52 | 11.59 | 78 | 123436 | 9915 | 29441098 |
Therapy interrupted | 12.49 | 11.59 | 10 | 123504 | 8376 | 29442637 |
Bronchospasm | 12.48 | 11.59 | 13 | 123501 | 9596 | 29441417 |
Ischaemic cardiomyopathy | 12.46 | 11.59 | 4 | 123510 | 5634 | 29445379 |
Pulmonary eosinophilia | 12.46 | 11.59 | 9 | 123505 | 211 | 29450802 |
Skin lesion | 12.46 | 11.59 | 38 | 123476 | 18534 | 29432479 |
Locomotive syndrome | 12.44 | 11.59 | 4 | 123510 | 12 | 29451001 |
Monorchidism | 12.44 | 11.59 | 4 | 123510 | 12 | 29451001 |
Seasonal allergy | 12.43 | 11.59 | 3 | 123511 | 5099 | 29445914 |
Nocturia | 12.42 | 11.59 | 10 | 123504 | 8352 | 29442661 |
Illusion | 12.42 | 11.59 | 15 | 123499 | 687 | 29450326 |
Post-acute COVID-19 syndrome | 12.41 | 11.59 | 5 | 123509 | 33 | 29450980 |
Laryngitis | 12.39 | 11.59 | 27 | 123487 | 2044 | 29448969 |
Urosepsis | 12.38 | 11.59 | 16 | 123498 | 10730 | 29440283 |
Bronchiectasis | 12.37 | 11.59 | 6 | 123508 | 6579 | 29444434 |
Renal cyst | 12.33 | 11.59 | 9 | 123505 | 7898 | 29443115 |
Drug withdrawal syndrome | 12.30 | 11.59 | 122 | 123392 | 17862 | 29433151 |
Respiratory fatigue | 12.26 | 11.59 | 6 | 123508 | 66 | 29450947 |
Progressive multifocal leukoencephalopathy | 12.25 | 11.59 | 11 | 123503 | 8708 | 29442305 |
Feeling of despair | 12.10 | 11.59 | 17 | 123497 | 905 | 29450108 |
Spinal fracture | 12.05 | 11.59 | 6 | 123508 | 6480 | 29444533 |
Cytotoxic oedema | 12.04 | 11.59 | 8 | 123506 | 163 | 29450850 |
Neurotoxicity | 12.02 | 11.59 | 27 | 123487 | 14586 | 29436427 |
Polydipsia psychogenic | 12.01 | 11.59 | 7 | 123507 | 112 | 29450901 |
Heparin-induced thrombocytopenia | 11.99 | 11.59 | 3 | 123511 | 4976 | 29446037 |
Hypotony maculopathy | 11.97 | 11.59 | 4 | 123510 | 14 | 29450999 |
Back disorder | 11.91 | 11.59 | 5 | 123509 | 5968 | 29445045 |
Burning sensation | 11.88 | 11.59 | 31 | 123483 | 15907 | 29435106 |
Anticoagulation drug level decreased | 11.88 | 11.59 | 6 | 123508 | 71 | 29450942 |
Posterior reversible encephalopathy syndrome | 11.84 | 11.59 | 71 | 123443 | 8905 | 29442108 |
Coronary artery stenosis | 11.83 | 11.59 | 11 | 123503 | 8562 | 29442451 |
Congenital multiplex arthrogryposis | 11.81 | 11.59 | 5 | 123509 | 38 | 29450975 |
Pica | 11.76 | 11.59 | 4 | 123510 | 15 | 29450998 |
Cardiovascular disorder | 11.70 | 11.59 | 12 | 123502 | 8923 | 29442090 |
Blunted affect | 11.68 | 11.59 | 10 | 123504 | 302 | 29450711 |
Anodontia | 11.66 | 11.59 | 6 | 123508 | 74 | 29450939 |
Mitochondrial cytopathy | 11.63 | 11.59 | 8 | 123506 | 173 | 29450840 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Seizure | 2362.85 | 10.74 | 2628 | 180311 | 164264 | 64151529 |
Hyperammonaemia | 2257.37 | 10.74 | 902 | 182037 | 9002 | 64306791 |
Drug interaction | 1945.57 | 10.74 | 3588 | 179351 | 358495 | 63957298 |
Hyperammonaemic encephalopathy | 1804.50 | 10.74 | 605 | 182334 | 3453 | 64312340 |
Status epilepticus | 1219.38 | 10.74 | 762 | 182177 | 20901 | 64294892 |
Aggression | 1120.22 | 10.74 | 978 | 181961 | 45254 | 64270539 |
Neuroleptic malignant syndrome | 1088.94 | 10.74 | 749 | 182190 | 24247 | 64291546 |
Somnolence | 1054.73 | 10.74 | 1990 | 180949 | 201655 | 64114138 |
Sopor | 859.81 | 10.74 | 696 | 182243 | 28965 | 64286828 |
Epilepsy | 827.57 | 10.74 | 717 | 182222 | 32814 | 64282979 |
Extrapyramidal disorder | 715.67 | 10.74 | 527 | 182412 | 19025 | 64296768 |
Generalised tonic-clonic seizure | 695.77 | 10.74 | 703 | 182236 | 39154 | 64276639 |
Ammonia increased | 692.87 | 10.74 | 356 | 182583 | 6621 | 64309172 |
Granulocytopenia | 686.99 | 10.74 | 406 | 182533 | 10034 | 64305759 |
Psychotic disorder | 670.65 | 10.74 | 646 | 182293 | 33932 | 64281861 |
Arthralgia | 613.71 | 10.74 | 244 | 182695 | 442016 | 63873777 |
Parkinsonism | 612.47 | 10.74 | 425 | 182514 | 13948 | 64301845 |
Mania | 607.40 | 10.74 | 444 | 182495 | 15842 | 64299951 |
Toxicity to various agents | 596.32 | 10.74 | 2319 | 180620 | 361194 | 63954599 |
Coma | 595.46 | 10.74 | 966 | 181973 | 86649 | 64229144 |
Intentional overdose | 592.79 | 10.74 | 978 | 181961 | 88966 | 64226827 |
Agitation | 578.54 | 10.74 | 958 | 181981 | 87409 | 64228384 |
Dyspnoea | 551.18 | 10.74 | 742 | 182197 | 717932 | 63597861 |
Overdose | 540.10 | 10.74 | 1313 | 181626 | 158253 | 64157540 |
Pain | 509.09 | 10.74 | 493 | 182446 | 553018 | 63762775 |
Intentional self-injury | 488.12 | 10.74 | 502 | 182437 | 28542 | 64287251 |
Multiple-drug resistance | 484.01 | 10.74 | 274 | 182665 | 6228 | 64309565 |
Abnormal behaviour | 476.65 | 10.74 | 531 | 182408 | 33091 | 64282702 |
Petit mal epilepsy | 465.94 | 10.74 | 245 | 182694 | 4787 | 64311006 |
Sedation | 463.72 | 10.74 | 580 | 182359 | 40882 | 64274911 |
Drug level increased | 442.29 | 10.74 | 515 | 182424 | 33681 | 64282112 |
Diarrhoea | 432.90 | 10.74 | 876 | 182063 | 721828 | 63593965 |
Tremor | 417.01 | 10.74 | 1138 | 181801 | 147092 | 64168701 |
Ataxia | 410.17 | 10.74 | 403 | 182536 | 21681 | 64294112 |
Depressed level of consciousness | 404.71 | 10.74 | 783 | 182156 | 80653 | 64235140 |
Rheumatoid arthritis | 403.48 | 10.74 | 14 | 182925 | 164280 | 64151513 |
Salivary hypersecretion | 395.53 | 10.74 | 305 | 182634 | 11808 | 64303985 |
Joint swelling | 387.88 | 10.74 | 71 | 182868 | 215311 | 64100482 |
Suicide attempt | 380.40 | 10.74 | 705 | 182234 | 70302 | 64245491 |
Drug reaction with eosinophilia and systemic symptoms | 379.39 | 10.74 | 606 | 182333 | 53611 | 64262182 |
Cognitive disorder | 364.09 | 10.74 | 600 | 182339 | 54487 | 64261306 |
Fatigue | 356.06 | 10.74 | 1024 | 181915 | 747706 | 63568087 |
Irritability | 344.01 | 10.74 | 471 | 182468 | 36275 | 64279518 |
Anticonvulsant drug level increased | 340.88 | 10.74 | 156 | 182783 | 2221 | 64313572 |
Infusion related reaction | 328.73 | 10.74 | 40 | 182899 | 164427 | 64151366 |
Drug level decreased | 320.75 | 10.74 | 264 | 182675 | 11239 | 64304554 |
Nausea | 315.73 | 10.74 | 1158 | 181781 | 784642 | 63531151 |
Blood creatine phosphokinase increased | 313.10 | 10.74 | 581 | 182358 | 57977 | 64257816 |
Peripheral swelling | 305.33 | 10.74 | 106 | 182833 | 209047 | 64106746 |
Foetal anticonvulsant syndrome | 303.36 | 10.74 | 80 | 182859 | 156 | 64315637 |
Catatonia | 302.95 | 10.74 | 216 | 182723 | 7404 | 64308389 |
Encephalopathy | 301.31 | 10.74 | 573 | 182366 | 58246 | 64257547 |
Delusion | 300.18 | 10.74 | 310 | 182629 | 17704 | 64298089 |
Antipsychotic drug level increased | 297.99 | 10.74 | 184 | 182755 | 4931 | 64310862 |
Schizophrenia | 294.16 | 10.74 | 248 | 182691 | 10920 | 64304873 |
Pain in extremity | 292.12 | 10.74 | 258 | 182681 | 302827 | 64012966 |
Hallucination, auditory | 283.16 | 10.74 | 292 | 182647 | 16647 | 64299146 |
Altered state of consciousness | 280.85 | 10.74 | 435 | 182504 | 37467 | 64278326 |
Electroencephalogram abnormal | 275.09 | 10.74 | 176 | 182763 | 5027 | 64310766 |
Hypernatraemia | 271.42 | 10.74 | 246 | 182693 | 11943 | 64303850 |
Drug abuse | 270.09 | 10.74 | 908 | 182031 | 131466 | 64184327 |
Anticonvulsant drug level decreased | 268.41 | 10.74 | 122 | 182817 | 1708 | 64314085 |
Febrile neutropenia | 267.25 | 10.74 | 99 | 182840 | 187558 | 64128235 |
Muscle rigidity | 266.78 | 10.74 | 287 | 182652 | 17186 | 64298607 |
Synovitis | 264.64 | 10.74 | 3 | 182936 | 99087 | 64216706 |
Arthropathy | 260.95 | 10.74 | 22 | 182917 | 120945 | 64194848 |
Psychomotor hyperactivity | 257.76 | 10.74 | 258 | 182681 | 14193 | 64301600 |
Treatment noncompliance | 254.80 | 10.74 | 449 | 182490 | 43033 | 64272760 |
Partial seizures | 254.00 | 10.74 | 191 | 182748 | 7116 | 64308677 |
Fanconi syndrome | 243.65 | 10.74 | 126 | 182813 | 2375 | 64313418 |
Dysmorphism | 241.97 | 10.74 | 81 | 182858 | 459 | 64315334 |
Myoclonic epilepsy | 241.54 | 10.74 | 109 | 182830 | 1499 | 64314294 |
Pneumonia aspiration | 237.90 | 10.74 | 522 | 182417 | 58749 | 64257044 |
Sudden unexplained death in epilepsy | 230.37 | 10.74 | 81 | 182858 | 544 | 64315249 |
Delirium | 228.00 | 10.74 | 564 | 182375 | 68630 | 64247163 |
Hypothermia | 227.12 | 10.74 | 281 | 182658 | 19575 | 64296218 |
Sinusitis | 227.06 | 10.74 | 66 | 182873 | 145862 | 64169931 |
Anticonvulsant drug level above therapeutic | 224.87 | 10.74 | 91 | 182848 | 939 | 64314854 |
Disorientation | 222.16 | 10.74 | 490 | 182449 | 55338 | 64260455 |
Tardive dyskinesia | 215.76 | 10.74 | 191 | 182748 | 8987 | 64306806 |
Nasopharyngitis | 213.99 | 10.74 | 147 | 182792 | 195926 | 64119867 |
Swelling | 212.67 | 10.74 | 94 | 182845 | 160124 | 64155669 |
Completed suicide | 212.49 | 10.74 | 1222 | 181717 | 223192 | 64092601 |
Bradyphrenia | 211.72 | 10.74 | 191 | 182748 | 9215 | 64306578 |
Cough | 210.91 | 10.74 | 332 | 182607 | 301816 | 64013977 |
Abdominal discomfort | 210.82 | 10.74 | 128 | 182811 | 182194 | 64133599 |
Drug withdrawal convulsions | 209.58 | 10.74 | 108 | 182831 | 2020 | 64313773 |
Disturbance in attention | 207.69 | 10.74 | 398 | 182541 | 40676 | 64275117 |
Suicidal ideation | 203.20 | 10.74 | 527 | 182412 | 66015 | 64249778 |
Headache | 199.91 | 10.74 | 799 | 182140 | 528668 | 63787125 |
Dysarthria | 198.66 | 10.74 | 487 | 182452 | 58919 | 64256874 |
Intellectual disability | 192.58 | 10.74 | 81 | 182858 | 929 | 64314864 |
Hypersensitivity | 191.82 | 10.74 | 165 | 182774 | 196287 | 64119506 |
Depression | 190.73 | 10.74 | 1024 | 181915 | 182267 | 64133526 |
Dystonia | 190.57 | 10.74 | 251 | 182688 | 18614 | 64297179 |
Foetal exposure during pregnancy | 185.15 | 10.74 | 130 | 182809 | 4346 | 64311447 |
Myoclonus | 184.27 | 10.74 | 287 | 182652 | 24831 | 64290962 |
Back pain | 184.10 | 10.74 | 265 | 182674 | 249906 | 64065887 |
Anaemia | 182.86 | 10.74 | 513 | 182426 | 378167 | 63937626 |
Cardiac failure congestive | 182.33 | 10.74 | 71 | 182868 | 130509 | 64185284 |
Psychomotor retardation | 182.25 | 10.74 | 136 | 182803 | 5007 | 64310786 |
Akathisia | 180.90 | 10.74 | 192 | 182747 | 11318 | 64304475 |
Mental impairment | 178.48 | 10.74 | 226 | 182713 | 16117 | 64299676 |
Anticonvulsant drug level below therapeutic | 178.29 | 10.74 | 77 | 182862 | 947 | 64314846 |
Stevens-Johnson syndrome | 178.26 | 10.74 | 336 | 182603 | 33913 | 64281880 |
Confusional state | 177.97 | 10.74 | 1309 | 181630 | 259835 | 64055958 |
Pruritus | 177.52 | 10.74 | 389 | 182550 | 312011 | 64003782 |
Dyskinesia | 173.13 | 10.74 | 360 | 182579 | 39028 | 64276765 |
Speech disorder | 170.41 | 10.74 | 405 | 182534 | 48036 | 64267757 |
Chest pain | 169.68 | 10.74 | 254 | 182685 | 235726 | 64080067 |
Bipolar disorder | 169.59 | 10.74 | 146 | 182793 | 6615 | 64309178 |
Psychogenic seizure | 165.80 | 10.74 | 88 | 182851 | 1753 | 64314040 |
Hepatic function abnormal | 163.20 | 10.74 | 476 | 182463 | 63837 | 64251956 |
Psychomotor skills impaired | 157.48 | 10.74 | 111 | 182828 | 3734 | 64312059 |
Mental disorder | 156.10 | 10.74 | 274 | 182665 | 26171 | 64289622 |
Paranoia | 155.12 | 10.74 | 211 | 182728 | 16141 | 64299652 |
Atrial fibrillation | 154.81 | 10.74 | 154 | 182785 | 170935 | 64144858 |
Neuropathy peripheral | 154.28 | 10.74 | 70 | 182869 | 117455 | 64198338 |
Drug ineffective | 153.71 | 10.74 | 3282 | 179657 | 836965 | 63478828 |
Paradoxical drug reaction | 153.19 | 10.74 | 132 | 182807 | 5988 | 64309805 |
Myocarditis | 152.79 | 10.74 | 214 | 182725 | 16829 | 64298964 |
Stupor | 152.75 | 10.74 | 131 | 182808 | 5904 | 64309889 |
Hypomania | 151.87 | 10.74 | 127 | 182812 | 5527 | 64310266 |
Focal dyscognitive seizures | 151.30 | 10.74 | 102 | 182837 | 3188 | 64312605 |
Contraindicated product administered | 149.92 | 10.74 | 59 | 182880 | 107770 | 64208023 |
Toxic encephalopathy | 147.69 | 10.74 | 160 | 182779 | 9655 | 64306138 |
Gastrointestinal haemorrhage | 147.25 | 10.74 | 97 | 182842 | 132215 | 64183578 |
Restlessness | 144.69 | 10.74 | 337 | 182602 | 39448 | 64276345 |
Myocardial infarction | 144.66 | 10.74 | 154 | 182785 | 165667 | 64150126 |
Drug intolerance | 144.39 | 10.74 | 193 | 182746 | 187799 | 64127994 |
Nystagmus | 143.81 | 10.74 | 152 | 182787 | 8916 | 64306877 |
Developmental delay | 142.27 | 10.74 | 66 | 182873 | 971 | 64314822 |
Drug ineffective for unapproved indication | 142.07 | 10.74 | 289 | 182650 | 30844 | 64284949 |
Speech disorder developmental | 141.65 | 10.74 | 55 | 182884 | 504 | 64315289 |
Autism spectrum disorder | 138.85 | 10.74 | 63 | 182876 | 878 | 64314915 |
Injection site pain | 137.66 | 10.74 | 72 | 182867 | 111336 | 64204457 |
Arthritis | 135.78 | 10.74 | 35 | 182904 | 83779 | 64232014 |
Persecutory delusion | 134.21 | 10.74 | 104 | 182835 | 4054 | 64311739 |
Abdominal pain upper | 134.10 | 10.74 | 180 | 182759 | 174850 | 64140943 |
Drug resistance | 130.58 | 10.74 | 300 | 182639 | 34802 | 64280991 |
Brain oedema | 129.35 | 10.74 | 228 | 182711 | 21847 | 64293946 |
Oculogyric crisis | 127.15 | 10.74 | 83 | 182856 | 2455 | 64313338 |
Eosinophilia | 127.11 | 10.74 | 312 | 182627 | 37764 | 64278029 |
Schizoaffective disorder | 126.60 | 10.74 | 70 | 182869 | 1517 | 64314276 |
Leukopenia | 125.90 | 10.74 | 595 | 182344 | 100647 | 64215146 |
Behaviour disorder | 125.63 | 10.74 | 103 | 182836 | 4359 | 64311434 |
Wrong patient received product | 125.59 | 10.74 | 96 | 182843 | 3666 | 64312127 |
Systemic lupus erythematosus | 124.60 | 10.74 | 33 | 182906 | 77579 | 64238214 |
Electrocardiogram QT prolonged | 124.05 | 10.74 | 500 | 182439 | 78948 | 64236845 |
Acute kidney injury | 121.15 | 10.74 | 762 | 182177 | 448478 | 63867315 |
Thrombocytopenia | 119.83 | 10.74 | 1062 | 181877 | 222739 | 64093054 |
Blood pressure increased | 118.94 | 10.74 | 191 | 182748 | 172361 | 64143432 |
Priapism | 118.88 | 10.74 | 95 | 182844 | 3875 | 64311918 |
Interstitial lung disease | 118.05 | 10.74 | 65 | 182874 | 97667 | 64218126 |
Mental status changes | 116.28 | 10.74 | 410 | 182529 | 60752 | 64255041 |
Herpes zoster | 115.68 | 10.74 | 40 | 182899 | 79147 | 64236646 |
Malignant neoplasm progression | 113.56 | 10.74 | 92 | 182847 | 112779 | 64203014 |
Asterixis | 112.84 | 10.74 | 75 | 182864 | 2288 | 64313505 |
Glossodynia | 112.81 | 10.74 | 23 | 182916 | 64673 | 64251120 |
Rhabdomyolysis | 111.81 | 10.74 | 536 | 182403 | 91190 | 64224603 |
Disease progression | 111.28 | 10.74 | 143 | 182796 | 141537 | 64174256 |
Urticaria | 110.32 | 10.74 | 154 | 182785 | 147163 | 64168630 |
Injection site erythema | 110.12 | 10.74 | 32 | 182907 | 70768 | 64245025 |
Cerebral atrophy | 110.03 | 10.74 | 119 | 182820 | 7166 | 64308627 |
Dyspnoea exertional | 109.87 | 10.74 | 36 | 182903 | 73694 | 64242099 |
Affect lability | 107.29 | 10.74 | 130 | 182809 | 8860 | 64306933 |
Abdominal pain | 106.20 | 10.74 | 490 | 182449 | 311885 | 64003908 |
Carnitine deficiency | 104.27 | 10.74 | 34 | 182905 | 175 | 64315618 |
Bradykinesia | 104.10 | 10.74 | 110 | 182829 | 6450 | 64309343 |
Drug level below therapeutic | 103.53 | 10.74 | 116 | 182823 | 7268 | 64308525 |
Discomfort | 103.31 | 10.74 | 50 | 182889 | 80828 | 64234965 |
Influenza | 103.28 | 10.74 | 90 | 182849 | 106441 | 64209352 |
Lethargy | 103.24 | 10.74 | 444 | 182495 | 72150 | 64243643 |
Eosinophilic pleural effusion | 102.99 | 10.74 | 36 | 182903 | 237 | 64315556 |
Atonic seizures | 102.82 | 10.74 | 46 | 182893 | 619 | 64315174 |
Psychiatric symptom | 102.78 | 10.74 | 107 | 182832 | 6166 | 64309627 |
Hyperprolactinaemia | 102.40 | 10.74 | 88 | 182851 | 3977 | 64311816 |
Death | 101.70 | 10.74 | 878 | 182061 | 481827 | 63833966 |
Learning disorder | 101.48 | 10.74 | 43 | 182896 | 503 | 64315290 |
Antipsychotic drug level above therapeutic | 100.99 | 10.74 | 64 | 182875 | 1797 | 64313996 |
Impaired healing | 100.38 | 10.74 | 24 | 182915 | 60449 | 64255344 |
Fluid retention | 100.24 | 10.74 | 23 | 182916 | 59583 | 64256210 |
Chest discomfort | 99.93 | 10.74 | 109 | 182830 | 115997 | 64199796 |
Antipsychotic drug level below therapeutic | 99.93 | 10.74 | 51 | 182888 | 934 | 64314859 |
Myalgia | 99.79 | 10.74 | 186 | 182753 | 158431 | 64157362 |
Osteoarthritis | 99.66 | 10.74 | 28 | 182911 | 63308 | 64252485 |
Thrombosis | 99.26 | 10.74 | 38 | 182901 | 70604 | 64245189 |
Hypoaesthesia | 98.69 | 10.74 | 151 | 182788 | 138957 | 64176836 |
Acidosis hyperchloraemic | 97.92 | 10.74 | 45 | 182894 | 647 | 64315146 |
Neutrophil count increased | 97.91 | 10.74 | 219 | 182720 | 24955 | 64290838 |
Tonic convulsion | 97.88 | 10.74 | 63 | 182876 | 1818 | 64313975 |
Hypotonia | 97.86 | 10.74 | 139 | 182800 | 11073 | 64304720 |
Asthenia | 97.70 | 10.74 | 762 | 182177 | 427282 | 63888511 |
Impulsive behaviour | 95.66 | 10.74 | 71 | 182868 | 2592 | 64313201 |
Wound | 95.09 | 10.74 | 49 | 182890 | 76428 | 64239365 |
Plasma cell myeloma | 95.02 | 10.74 | 10 | 182929 | 46065 | 64269728 |
Thinking abnormal | 94.63 | 10.74 | 139 | 182800 | 11417 | 64304376 |
Pleurothotonus | 93.22 | 10.74 | 66 | 182873 | 2236 | 64313557 |
Stomatitis | 93.11 | 10.74 | 104 | 182835 | 109501 | 64206292 |
Seizure cluster | 92.89 | 10.74 | 36 | 182903 | 328 | 64315465 |
White blood cell count increased | 92.52 | 10.74 | 402 | 182537 | 65612 | 64250181 |
Bipolar I disorder | 88.92 | 10.74 | 58 | 182881 | 1713 | 64314080 |
Blood prolactin increased | 88.11 | 10.74 | 76 | 182863 | 3452 | 64312341 |
Hypertonia | 88.06 | 10.74 | 99 | 182840 | 6226 | 64309567 |
Product residue present | 87.45 | 10.74 | 73 | 182866 | 3169 | 64312624 |
Dysphoria | 86.95 | 10.74 | 83 | 182856 | 4305 | 64311488 |
Cerebellar atrophy | 84.90 | 10.74 | 47 | 182892 | 1021 | 64314772 |
Metabolic acidosis | 83.12 | 10.74 | 410 | 182529 | 70548 | 64245245 |
Musculoskeletal pain | 82.09 | 10.74 | 66 | 182873 | 81228 | 64234565 |
Malaise | 81.94 | 10.74 | 724 | 182215 | 395523 | 63920270 |
Duodenal ulcer perforation | 81.43 | 10.74 | 4 | 182935 | 34621 | 64281172 |
Euphoric mood | 79.78 | 10.74 | 96 | 182843 | 6495 | 64309298 |
Oppositional defiant disorder | 79.59 | 10.74 | 35 | 182904 | 451 | 64315342 |
Mucosal inflammation | 79.46 | 10.74 | 39 | 182900 | 62545 | 64253248 |
Bronchitis | 79.09 | 10.74 | 116 | 182823 | 108627 | 64207166 |
Psychotic symptom | 79.04 | 10.74 | 58 | 182881 | 2080 | 64313713 |
Loss of consciousness | 78.79 | 10.74 | 703 | 182236 | 147662 | 64168131 |
Toxic epidermal necrolysis | 78.40 | 10.74 | 258 | 182681 | 36908 | 64278885 |
Psoriatic arthropathy | 78.40 | 10.74 | 14 | 182925 | 43267 | 64272526 |
Differential white blood cell count abnormal | 78.21 | 10.74 | 54 | 182885 | 1756 | 64314037 |
Coordination abnormal | 78.09 | 10.74 | 147 | 182792 | 14817 | 64300976 |
Pancreatitis acute | 77.79 | 10.74 | 283 | 182656 | 42572 | 64273221 |
Helicobacter infection | 77.40 | 10.74 | 9 | 182930 | 38353 | 64277440 |
Drug hypersensitivity | 77.28 | 10.74 | 379 | 182560 | 237436 | 64078357 |
Product substitution issue | 77.01 | 10.74 | 162 | 182777 | 17699 | 64298094 |
Pneumonia | 76.60 | 10.74 | 1122 | 181817 | 558454 | 63757339 |
Anger | 76.46 | 10.74 | 150 | 182789 | 15591 | 64300202 |
Epistaxis | 76.05 | 10.74 | 100 | 182839 | 98031 | 64217762 |
Infantile spasms | 75.83 | 10.74 | 29 | 182910 | 254 | 64315539 |
Chills | 75.32 | 10.74 | 174 | 182765 | 137090 | 64178703 |
Rash | 74.97 | 10.74 | 886 | 182053 | 457663 | 63858130 |
Cardiac failure | 74.91 | 10.74 | 165 | 182774 | 132208 | 64183585 |
Flushing | 74.35 | 10.74 | 68 | 182871 | 78580 | 64237213 |
Cerebrovascular accident | 74.22 | 10.74 | 176 | 182763 | 137407 | 64178386 |
Gaze palsy | 74.19 | 10.74 | 60 | 182879 | 2490 | 64313303 |
Psoriasis | 73.93 | 10.74 | 57 | 182882 | 71646 | 64244147 |
Rhinorrhoea | 73.70 | 10.74 | 39 | 182900 | 59930 | 64255863 |
Therapeutic product effect decreased | 73.66 | 10.74 | 134 | 182805 | 115217 | 64200576 |
Drooling | 73.62 | 10.74 | 83 | 182856 | 5236 | 64310557 |
Injection site pruritus | 73.58 | 10.74 | 10 | 182929 | 37816 | 64277977 |
Antipsychotic drug level decreased | 73.56 | 10.74 | 41 | 182898 | 903 | 64314890 |
Muscle spasms | 73.24 | 10.74 | 184 | 182755 | 140839 | 64174954 |
Dysmetria | 72.79 | 10.74 | 40 | 182899 | 856 | 64314937 |
Delusion of grandeur | 72.53 | 10.74 | 35 | 182904 | 565 | 64315228 |
Gait disturbance | 72.00 | 10.74 | 776 | 182163 | 171379 | 64144414 |
Renal failure | 71.62 | 10.74 | 269 | 182670 | 181419 | 64134374 |
Inappropriate antidiuretic hormone secretion | 71.60 | 10.74 | 180 | 182759 | 22109 | 64293684 |
Communication disorder | 71.35 | 10.74 | 69 | 182870 | 3637 | 64312156 |
Injection site reaction | 70.91 | 10.74 | 22 | 182917 | 46642 | 64269151 |
Haematochezia | 70.70 | 10.74 | 51 | 182888 | 66322 | 64249471 |
Poisoning | 70.61 | 10.74 | 177 | 182762 | 21702 | 64294091 |
Anaphylactic reaction | 70.27 | 10.74 | 55 | 182884 | 68609 | 64247184 |
Apathy | 69.70 | 10.74 | 119 | 182820 | 11113 | 64304680 |
Injection site swelling | 69.45 | 10.74 | 16 | 182923 | 41337 | 64274456 |
Hyponatraemia | 68.83 | 10.74 | 683 | 182256 | 147656 | 64168137 |
Blood lactic acid increased | 68.28 | 10.74 | 113 | 182826 | 10288 | 64305505 |
Neutropenia | 68.06 | 10.74 | 1005 | 181934 | 238619 | 64077174 |
Paraesthesia | 67.94 | 10.74 | 178 | 182761 | 134344 | 64181449 |
Logorrhoea | 67.88 | 10.74 | 70 | 182869 | 3989 | 64311804 |
Respiratory depression | 67.79 | 10.74 | 182 | 182757 | 23261 | 64292532 |
Contusion | 67.03 | 10.74 | 139 | 182800 | 113826 | 64201967 |
Propofol infusion syndrome | 66.96 | 10.74 | 47 | 182892 | 1570 | 64314223 |
Acute hepatic failure | 66.92 | 10.74 | 194 | 182745 | 25918 | 64289875 |
Oedema peripheral | 66.70 | 10.74 | 338 | 182601 | 209979 | 64105814 |
Cogwheel rigidity | 66.31 | 10.74 | 59 | 182880 | 2794 | 64312999 |
Acute myocardial infarction | 66.24 | 10.74 | 60 | 182879 | 69658 | 64246135 |
Erythema | 66.16 | 10.74 | 289 | 182650 | 186781 | 64129012 |
Hyperkinesia | 65.93 | 10.74 | 56 | 182883 | 2490 | 64313303 |
Carnitine decreased | 65.44 | 10.74 | 14 | 182925 | 3 | 64315790 |
Homicidal ideation | 65.28 | 10.74 | 62 | 182877 | 3195 | 64312598 |
Tonic clonic movements | 64.74 | 10.74 | 50 | 182889 | 1939 | 64313854 |
Hot flush | 64.73 | 10.74 | 25 | 182914 | 46210 | 64269583 |
Decreased eye contact | 64.50 | 10.74 | 35 | 182904 | 730 | 64315063 |
Hyperlactacidaemia | 64.35 | 10.74 | 74 | 182865 | 4770 | 64311023 |
Hallucination | 63.98 | 10.74 | 389 | 182550 | 72399 | 64243394 |
Attention deficit hyperactivity disorder | 63.82 | 10.74 | 57 | 182882 | 2713 | 64313080 |
Tachycardia | 63.35 | 10.74 | 676 | 182263 | 148903 | 64166890 |
Infection | 63.35 | 10.74 | 289 | 182650 | 184591 | 64131202 |
Urinary tract infection | 63.23 | 10.74 | 391 | 182548 | 231205 | 64084588 |
Resting tremor | 63.02 | 10.74 | 43 | 182896 | 1371 | 64314422 |
Unresponsive to stimuli | 62.48 | 10.74 | 296 | 182643 | 50097 | 64265696 |
Coronary artery disease | 62.35 | 10.74 | 48 | 182891 | 60385 | 64255408 |
Alopecia | 62.29 | 10.74 | 250 | 182689 | 165440 | 64150353 |
Hallucination, visual | 62.13 | 10.74 | 197 | 182742 | 27637 | 64288156 |
Intentional product use issue | 61.58 | 10.74 | 110 | 182829 | 95254 | 64220539 |
Necrosis ischaemic | 61.46 | 10.74 | 37 | 182902 | 946 | 64314847 |
Psychiatric decompensation | 61.39 | 10.74 | 53 | 182886 | 2410 | 64313383 |
Pancreatitis | 60.52 | 10.74 | 331 | 182608 | 59276 | 64256517 |
Urinary incontinence | 60.02 | 10.74 | 232 | 182707 | 35919 | 64279874 |
Drug level changed | 60.00 | 10.74 | 29 | 182910 | 470 | 64315323 |
Prescribed overdose | 59.96 | 10.74 | 159 | 182780 | 20172 | 64295621 |
Enuresis | 59.55 | 10.74 | 55 | 182884 | 2735 | 64313058 |
Grandiosity | 59.49 | 10.74 | 30 | 182909 | 535 | 64315258 |
Depressed mood | 59.18 | 10.74 | 252 | 182687 | 40760 | 64275033 |
Inflammation | 58.76 | 10.74 | 59 | 182880 | 65241 | 64250552 |
Bone pain | 58.37 | 10.74 | 31 | 182908 | 47541 | 64268252 |
Gingival hypertrophy | 58.34 | 10.74 | 54 | 182885 | 2693 | 64313100 |
Nasal congestion | 58.29 | 10.74 | 50 | 182889 | 59608 | 64256185 |
Pressure of speech | 58.28 | 10.74 | 36 | 182903 | 965 | 64314828 |
Blood pressure systolic increased | 58.11 | 10.74 | 34 | 182905 | 49419 | 64266374 |
Chorea | 58.06 | 10.74 | 47 | 182892 | 1953 | 64313840 |
Knee arthroplasty | 57.95 | 10.74 | 5 | 182934 | 26994 | 64288799 |
Hyperthermia | 57.93 | 10.74 | 133 | 182806 | 15417 | 64300376 |
Neoplasm progression | 57.60 | 10.74 | 22 | 182917 | 40942 | 64274851 |
Metabolic encephalopathy | 56.50 | 10.74 | 90 | 182849 | 7935 | 64307858 |
Throat irritation | 56.25 | 10.74 | 12 | 182927 | 32699 | 64283094 |
Folliculitis | 56.08 | 10.74 | 9 | 182930 | 30068 | 64285725 |
Obesity | 55.84 | 10.74 | 156 | 182783 | 20406 | 64295387 |
Retinogram abnormal | 55.65 | 10.74 | 24 | 182915 | 294 | 64315499 |
Mood altered | 55.53 | 10.74 | 133 | 182806 | 15846 | 64299947 |
Craniosynostosis | 55.40 | 10.74 | 17 | 182922 | 69 | 64315724 |
Gastrointestinal disorder | 54.81 | 10.74 | 107 | 182832 | 89602 | 64226191 |
Learning disability | 54.71 | 10.74 | 21 | 182918 | 186 | 64315607 |
Haemoptysis | 54.48 | 10.74 | 36 | 182903 | 49012 | 64266781 |
Oropharyngeal pain | 54.30 | 10.74 | 106 | 182833 | 88761 | 64227032 |
Congenital hand malformation | 53.55 | 10.74 | 11 | 182928 | 0 | 64315793 |
Mitochondrial DNA mutation | 53.52 | 10.74 | 22 | 182917 | 237 | 64315556 |
C-reactive protein abnormal | 53.47 | 10.74 | 9 | 182930 | 29038 | 64286755 |
Disinhibition | 53.36 | 10.74 | 47 | 182892 | 2196 | 64313597 |
Serotonin syndrome | 53.34 | 10.74 | 237 | 182702 | 39045 | 64276748 |
Hyperkalaemia | 53.24 | 10.74 | 131 | 182808 | 100998 | 64214795 |
Obsessive-compulsive disorder | 53.19 | 10.74 | 67 | 182872 | 4751 | 64311042 |
Dehydration | 53.10 | 10.74 | 378 | 182561 | 216385 | 64099408 |
Hyperosmolar state | 53.05 | 10.74 | 29 | 182910 | 614 | 64315179 |
Autonomic nervous system imbalance | 53.01 | 10.74 | 62 | 182877 | 4070 | 64311723 |
Mydriasis | 52.73 | 10.74 | 127 | 182812 | 15185 | 64300608 |
Pain in jaw | 52.34 | 10.74 | 25 | 182914 | 40730 | 64275063 |
Dry skin | 52.32 | 10.74 | 41 | 182898 | 51120 | 64264673 |
Gastrooesophageal reflux disease | 51.82 | 10.74 | 98 | 182841 | 83045 | 64232748 |
Osteonecrosis of jaw | 51.80 | 10.74 | 24 | 182915 | 39801 | 64275992 |
Dysgeusia | 51.63 | 10.74 | 35 | 182904 | 47012 | 64268781 |
Partial seizures with secondary generalisation | 51.44 | 10.74 | 26 | 182913 | 466 | 64315327 |
Muscle injury | 51.40 | 10.74 | 7 | 182932 | 26430 | 64289363 |
Ascites | 51.37 | 10.74 | 60 | 182879 | 61941 | 64253852 |
Intestinal ischaemia | 51.25 | 10.74 | 106 | 182833 | 11443 | 64304350 |
Hypokinesia | 51.20 | 10.74 | 132 | 182807 | 16464 | 64299329 |
Pulmonary arterial hypertension | 51.06 | 10.74 | 6 | 182933 | 25361 | 64290432 |
Conjunctival hyperaemia | 50.85 | 10.74 | 59 | 182880 | 3840 | 64311953 |
Hypertension | 50.78 | 10.74 | 480 | 182459 | 258781 | 64057012 |
Pneumonitis | 50.70 | 10.74 | 41 | 182898 | 50324 | 64265469 |
Physical assault | 50.62 | 10.74 | 39 | 182900 | 1507 | 64314286 |
Injection site bruising | 50.37 | 10.74 | 20 | 182919 | 36353 | 64279440 |
Product dose omission issue | 49.97 | 10.74 | 335 | 182604 | 194412 | 64121381 |
Encephalitis autoimmune | 49.94 | 10.74 | 42 | 182897 | 1842 | 64313951 |
General physical health deterioration | 49.82 | 10.74 | 357 | 182582 | 204068 | 64111725 |
Blood pressure fluctuation | 48.84 | 10.74 | 45 | 182894 | 51826 | 64263967 |
Posture abnormal | 48.60 | 10.74 | 54 | 182885 | 3352 | 64312441 |
Diabetes insipidus | 48.54 | 10.74 | 62 | 182877 | 4459 | 64311334 |
Choreoathetosis | 48.47 | 10.74 | 37 | 182902 | 1410 | 64314383 |
Postictal state | 48.31 | 10.74 | 39 | 182900 | 1614 | 64314179 |
Weight decreased | 48.20 | 10.74 | 548 | 182391 | 285191 | 64030602 |
Heart rate decreased | 48.14 | 10.74 | 51 | 182888 | 55016 | 64260777 |
Drop attacks | 47.95 | 10.74 | 32 | 182907 | 983 | 64314810 |
Sluggishness | 47.58 | 10.74 | 69 | 182870 | 5601 | 64310192 |
Language disorder | 47.51 | 10.74 | 48 | 182891 | 2669 | 64313124 |
Feeling hot | 47.45 | 10.74 | 36 | 182903 | 45627 | 64270166 |
Rectal haemorrhage | 46.87 | 10.74 | 64 | 182875 | 61753 | 64254040 |
Sexually inappropriate behaviour | 46.81 | 10.74 | 24 | 182915 | 444 | 64315349 |
Weight increased | 46.19 | 10.74 | 856 | 182083 | 212492 | 64103301 |
Diverticulitis | 46.16 | 10.74 | 26 | 182913 | 38592 | 64277201 |
Hyperglycinaemia | 46.07 | 10.74 | 10 | 182929 | 3 | 64315790 |
Basal cell carcinoma | 46.03 | 10.74 | 15 | 182924 | 30823 | 64284970 |
Nephrogenic diabetes insipidus | 45.81 | 10.74 | 40 | 182899 | 1847 | 64313946 |
Drug withdrawal syndrome | 45.71 | 10.74 | 193 | 182746 | 31098 | 64284695 |
Depressive symptom | 45.68 | 10.74 | 60 | 182879 | 4436 | 64311357 |
Miosis | 45.65 | 10.74 | 110 | 182829 | 13156 | 64302637 |
Leukocytosis | 45.57 | 10.74 | 220 | 182719 | 37520 | 64278273 |
Neovascularisation | 45.54 | 10.74 | 32 | 182907 | 1071 | 64314722 |
Cataract | 45.34 | 10.74 | 47 | 182892 | 51215 | 64264578 |
Night sweats | 44.94 | 10.74 | 23 | 182916 | 36023 | 64279770 |
COVID-19 | 44.94 | 10.74 | 72 | 182867 | 65068 | 64250725 |
Palmar-plantar erythrodysaesthesia syndrome | 44.85 | 10.74 | 13 | 182926 | 28806 | 64286987 |
Staring | 44.77 | 10.74 | 44 | 182895 | 2366 | 64313427 |
Intra-abdominal pressure increased | 44.41 | 10.74 | 19 | 182920 | 228 | 64315565 |
Angiofibroma | 44.34 | 10.74 | 16 | 182923 | 117 | 64315676 |
Educational problem | 44.15 | 10.74 | 22 | 182917 | 382 | 64315411 |
Pneumocystis jirovecii pneumonia | 43.87 | 10.74 | 12 | 182927 | 27622 | 64288171 |
Renal tubular acidosis | 43.84 | 10.74 | 48 | 182891 | 2931 | 64312862 |
Palpitations | 43.60 | 10.74 | 151 | 182788 | 104337 | 64211456 |
Hypospadias | 43.54 | 10.74 | 16 | 182923 | 124 | 64315669 |
Irritable bowel syndrome | 43.47 | 10.74 | 26 | 182913 | 37343 | 64278450 |
Suicidal behaviour | 43.32 | 10.74 | 47 | 182892 | 2840 | 64312953 |
Upper gastrointestinal haemorrhage | 43.13 | 10.74 | 23 | 182916 | 35197 | 64280596 |
Hypervolaemia | 42.66 | 10.74 | 28 | 182911 | 38257 | 64277536 |
Pulmonary hypertension | 42.33 | 10.74 | 36 | 182903 | 43103 | 64272690 |
Intentional product misuse | 42.24 | 10.74 | 350 | 182589 | 71945 | 64243848 |
Melaena | 42.06 | 10.74 | 54 | 182885 | 53494 | 64262299 |
Homicide | 42.04 | 10.74 | 31 | 182908 | 1120 | 64314673 |
Lung disorder | 41.96 | 10.74 | 67 | 182872 | 60633 | 64255160 |
Postictal psychosis | 41.85 | 10.74 | 16 | 182923 | 140 | 64315653 |
Delusional disorder, unspecified type | 41.76 | 10.74 | 26 | 182913 | 707 | 64315086 |
Cytokine release syndrome | 41.74 | 10.74 | 5 | 182934 | 20824 | 64294969 |
Erectile dysfunction | 41.63 | 10.74 | 103 | 182836 | 12524 | 64303269 |
Acute myeloid leukaemia | 41.63 | 10.74 | 13 | 182926 | 27450 | 64288343 |
Food interaction | 41.61 | 10.74 | 34 | 182905 | 1432 | 64314361 |
Anticonvulsant drug level abnormal | 41.56 | 10.74 | 13 | 182926 | 57 | 64315736 |
Hallucinations, mixed | 41.41 | 10.74 | 67 | 182872 | 5985 | 64309808 |
Agranulocytosis | 41.32 | 10.74 | 216 | 182723 | 38013 | 64277780 |
Mutism | 41.30 | 10.74 | 39 | 182900 | 1995 | 64313798 |
Postictal paralysis | 41.22 | 10.74 | 20 | 182919 | 327 | 64315466 |
Refusal of treatment by patient | 41.15 | 10.74 | 80 | 182859 | 8259 | 64307534 |
Rash maculo-papular | 41.11 | 10.74 | 251 | 182688 | 46775 | 64269018 |
Automatism | 41.07 | 10.74 | 16 | 182923 | 148 | 64315645 |
Oral mucosa erosion | 41.07 | 10.74 | 36 | 182903 | 1671 | 64314122 |
Bruxism | 40.97 | 10.74 | 51 | 182888 | 3573 | 64312220 |
Negativism | 40.90 | 10.74 | 26 | 182913 | 734 | 64315059 |
Cellulitis | 40.68 | 10.74 | 133 | 182806 | 93524 | 64222269 |
Change in seizure presentation | 40.45 | 10.74 | 19 | 182920 | 288 | 64315505 |
Cytomegalovirus infection | 40.38 | 10.74 | 28 | 182911 | 37171 | 64278622 |
Acute coronary syndrome | 40.31 | 10.74 | 4 | 182935 | 19306 | 64296487 |
Increased appetite | 40.27 | 10.74 | 89 | 182850 | 10057 | 64305736 |
Flight of ideas | 39.95 | 10.74 | 25 | 182914 | 686 | 64315107 |
Medication error | 39.53 | 10.74 | 260 | 182679 | 49706 | 64266087 |
Sepsis | 39.52 | 10.74 | 440 | 182499 | 229901 | 64085892 |
Dysgraphia | 39.49 | 10.74 | 49 | 182890 | 3422 | 64312371 |
Perseveration | 39.40 | 10.74 | 20 | 182919 | 362 | 64315431 |
Mood swings | 39.32 | 10.74 | 124 | 182815 | 17344 | 64298449 |
Brugada syndrome | 39.30 | 10.74 | 29 | 182910 | 1049 | 64314744 |
Angina pectoris | 39.13 | 10.74 | 42 | 182897 | 45039 | 64270754 |
Coma scale abnormal | 38.87 | 10.74 | 75 | 182864 | 7699 | 64308094 |
Drug level above therapeutic | 38.78 | 10.74 | 70 | 182869 | 6831 | 64308962 |
Confabulation | 38.70 | 10.74 | 21 | 182918 | 438 | 64315355 |
Affective disorder | 38.59 | 10.74 | 68 | 182871 | 6512 | 64309281 |
Dementia | 38.41 | 10.74 | 138 | 182801 | 20628 | 64295165 |
Dizziness | 38.38 | 10.74 | 928 | 182011 | 429235 | 63886558 |
Metastases to bone | 38.36 | 10.74 | 6 | 182933 | 20429 | 64295364 |
Aphasia | 38.11 | 10.74 | 222 | 182717 | 40684 | 64275109 |
Syncope | 38.04 | 10.74 | 276 | 182663 | 157359 | 64158434 |
Social avoidant behaviour | 37.58 | 10.74 | 55 | 182884 | 4502 | 64311291 |
Pulmonary embolism | 37.41 | 10.74 | 252 | 182687 | 146104 | 64169689 |
Pulmonary fibrosis | 37.35 | 10.74 | 19 | 182920 | 29859 | 64285934 |
Hypersexuality | 37.22 | 10.74 | 32 | 182907 | 1447 | 64314346 |
Mobility decreased | 37.21 | 10.74 | 122 | 182817 | 85718 | 64230075 |
Flatulence | 37.21 | 10.74 | 28 | 182911 | 35638 | 64280155 |
Pulmonary mass | 37.07 | 10.74 | 11 | 182928 | 24005 | 64291788 |
Bacteraemia | 36.93 | 10.74 | 15 | 182924 | 26896 | 64288897 |
Convulsive threshold lowered | 36.93 | 10.74 | 26 | 182913 | 873 | 64314920 |
Metastases to liver | 36.89 | 10.74 | 11 | 182928 | 23930 | 64291863 |
Breast hyperplasia | 36.77 | 10.74 | 14 | 182925 | 121 | 64315672 |
Cystitis | 36.77 | 10.74 | 40 | 182899 | 42635 | 64273158 |
Prostate cancer | 36.74 | 10.74 | 6 | 182933 | 19789 | 64296004 |
Tic | 36.47 | 10.74 | 41 | 182898 | 2578 | 64313215 |
Lennox-Gastaut syndrome | 36.39 | 10.74 | 16 | 182923 | 206 | 64315587 |
Soliloquy | 36.35 | 10.74 | 22 | 182917 | 568 | 64315225 |
Limbic encephalitis | 36.22 | 10.74 | 23 | 182916 | 648 | 64315145 |
Fibromyalgia | 36.07 | 10.74 | 29 | 182910 | 35702 | 64280091 |
Head titubation | 36.02 | 10.74 | 25 | 182914 | 820 | 64314973 |
Incoherent | 36.00 | 10.74 | 69 | 182870 | 7049 | 64308744 |
Gastric disorder | 35.85 | 10.74 | 19 | 182920 | 29178 | 64286615 |
Normal pressure hydrocephalus | 35.82 | 10.74 | 20 | 182919 | 442 | 64315351 |
Cryptorchism | 35.67 | 10.74 | 10 | 182929 | 27 | 64315766 |
Wheezing | 35.29 | 10.74 | 114 | 182825 | 80465 | 64235328 |
Aspergillus infection | 35.24 | 10.74 | 3 | 182936 | 16376 | 64299417 |
Ill-defined disorder | 35.04 | 10.74 | 44 | 182895 | 44008 | 64271785 |
Judgement impaired | 34.98 | 10.74 | 27 | 182912 | 1046 | 64314747 |
Bronchopulmonary aspergillosis | 34.94 | 10.74 | 6 | 182933 | 19079 | 64296714 |
Skin ulcer | 34.90 | 10.74 | 44 | 182895 | 43930 | 64271863 |
Adjustment disorder with mixed anxiety and depressed mood | 34.86 | 10.74 | 12 | 182927 | 75 | 64315718 |
Intensive care unit acquired weakness | 34.85 | 10.74 | 33 | 182906 | 1694 | 64314099 |
Musculoskeletal stiffness | 34.64 | 10.74 | 206 | 182733 | 123000 | 64192793 |
Platelet count decreased | 34.60 | 10.74 | 668 | 182271 | 167043 | 64148750 |
Transfusion | 34.43 | 10.74 | 5 | 182934 | 17989 | 64297804 |
Limb discomfort | 34.39 | 10.74 | 17 | 182922 | 27158 | 64288635 |
Tachyphrenia | 34.38 | 10.74 | 34 | 182905 | 1842 | 64313951 |
Echolalia | 34.35 | 10.74 | 18 | 182921 | 349 | 64315444 |
Fungal infection | 34.33 | 10.74 | 28 | 182911 | 34223 | 64281570 |
Oropharyngeal oedema | 34.27 | 10.74 | 16 | 182923 | 239 | 64315554 |
Anaphylactic shock | 34.03 | 10.74 | 22 | 182917 | 30306 | 64285487 |
Verbal abuse | 33.74 | 10.74 | 16 | 182923 | 248 | 64315545 |
Tumour lysis syndrome | 33.70 | 10.74 | 7 | 182932 | 19433 | 64296360 |
Localised infection | 33.68 | 10.74 | 22 | 182917 | 30139 | 64285654 |
Withdrawal syndrome | 33.62 | 10.74 | 144 | 182795 | 23348 | 64292445 |
Motor developmental delay | 33.13 | 10.74 | 15 | 182924 | 208 | 64315585 |
Metabolic syndrome | 33.11 | 10.74 | 37 | 182902 | 2311 | 64313482 |
Septic shock | 33.08 | 10.74 | 170 | 182769 | 105267 | 64210526 |
Memory impairment | 32.94 | 10.74 | 380 | 182559 | 85302 | 64230491 |
Brief psychotic disorder, with postpartum onset | 32.75 | 10.74 | 9 | 182930 | 22 | 64315771 |
Microcephaly | 32.72 | 10.74 | 14 | 182925 | 168 | 64315625 |
Faeces discoloured | 32.70 | 10.74 | 16 | 182923 | 25713 | 64290080 |
Akinesia | 32.70 | 10.74 | 42 | 182897 | 3037 | 64312756 |
Inappropriate affect | 32.68 | 10.74 | 28 | 182911 | 1260 | 64314533 |
Polydipsia | 32.66 | 10.74 | 59 | 182880 | 5762 | 64310031 |
Ileus paralytic | 32.48 | 10.74 | 73 | 182866 | 8342 | 64307451 |
Hepatic adenoma | 32.47 | 10.74 | 16 | 182923 | 271 | 64315522 |
Transaminases increased | 32.27 | 10.74 | 227 | 182712 | 44367 | 64271426 |
Monocyte count increased | 32.22 | 10.74 | 71 | 182868 | 8008 | 64307785 |
Tendonitis | 31.84 | 10.74 | 9 | 182930 | 20273 | 64295520 |
Sudden death | 31.76 | 10.74 | 127 | 182812 | 19969 | 64295824 |
Colitis | 31.67 | 10.74 | 75 | 182864 | 58599 | 64257194 |
Thought blocking | 31.59 | 10.74 | 14 | 182925 | 184 | 64315609 |
Breast cancer | 31.56 | 10.74 | 22 | 182917 | 29126 | 64286667 |
Joint stiffness | 31.55 | 10.74 | 24 | 182915 | 30380 | 64285413 |
Constipation | 31.54 | 10.74 | 459 | 182480 | 228878 | 64086915 |
Anion gap increased | 31.51 | 10.74 | 41 | 182898 | 3003 | 64312790 |
Stereotypy | 31.48 | 10.74 | 23 | 182916 | 819 | 64314974 |
Joint range of motion decreased | 31.47 | 10.74 | 8 | 182931 | 19335 | 64296458 |
Angiomyolipoma | 31.32 | 10.74 | 14 | 182925 | 188 | 64315605 |
Pancreatitis necrotising | 31.25 | 10.74 | 42 | 182897 | 3175 | 64312618 |
Excessive eye blinking | 31.18 | 10.74 | 27 | 182912 | 1233 | 64314560 |
Bursitis | 31.11 | 10.74 | 11 | 182928 | 21474 | 64294319 |
Aura | 31.05 | 10.74 | 23 | 182916 | 837 | 64314956 |
Cerebellar syndrome | 30.93 | 10.74 | 53 | 182886 | 4963 | 64310830 |
Hip arthroplasty | 30.80 | 10.74 | 11 | 182928 | 21340 | 64294453 |
Lower respiratory tract infection | 30.56 | 10.74 | 151 | 182788 | 94463 | 64221330 |
Hyperchloraemia | 30.54 | 10.74 | 24 | 182915 | 955 | 64314838 |
Mitochondrial cytopathy | 30.43 | 10.74 | 17 | 182922 | 376 | 64315417 |
Epileptic psychosis | 30.43 | 10.74 | 10 | 182929 | 53 | 64315740 |
Device expulsion | 30.30 | 10.74 | 11 | 182928 | 21125 | 64294668 |
Sinus congestion | 30.22 | 10.74 | 4 | 182935 | 15435 | 64300358 |
Epidermolysis bullosa | 30.17 | 10.74 | 14 | 182925 | 206 | 64315587 |
Porphyria acute | 29.98 | 10.74 | 21 | 182918 | 699 | 64315094 |
Kidney infection | 29.75 | 10.74 | 7 | 182932 | 17831 | 64297962 |
Schizoaffective disorder bipolar type | 29.72 | 10.74 | 12 | 182927 | 123 | 64315670 |
Screaming | 29.69 | 10.74 | 43 | 182896 | 3486 | 64312307 |
Borderline personality disorder | 29.67 | 10.74 | 22 | 182917 | 802 | 64314991 |
Distractibility | 29.64 | 10.74 | 20 | 182919 | 626 | 64315167 |
Rabbit syndrome | 29.56 | 10.74 | 16 | 182923 | 332 | 64315461 |
Right ventricular failure | 29.41 | 10.74 | 12 | 182927 | 21459 | 64294334 |
Poverty of speech | 29.16 | 10.74 | 19 | 182920 | 560 | 64315233 |
Upper respiratory tract infection | 29.15 | 10.74 | 107 | 182832 | 72678 | 64243115 |
Hepatic failure | 29.12 | 10.74 | 262 | 182677 | 55132 | 64260661 |
Neurodevelopmental disorder | 29.04 | 10.74 | 9 | 182930 | 38 | 64315755 |
Clostridium difficile infection | 28.89 | 10.74 | 36 | 182903 | 36127 | 64279666 |
Neurological decompensation | 28.85 | 10.74 | 48 | 182891 | 4388 | 64311405 |
Suspiciousness | 28.81 | 10.74 | 19 | 182920 | 572 | 64315221 |
Choking | 28.66 | 10.74 | 80 | 182859 | 10458 | 64305335 |
Product use in unapproved indication | 28.53 | 10.74 | 679 | 182260 | 175939 | 64139854 |
Haemorrhage | 28.39 | 10.74 | 122 | 182817 | 79229 | 64236564 |
Maternal exposure during pregnancy | 28.19 | 10.74 | 158 | 182781 | 95726 | 64220067 |
Ovarian granulosa-theca cell tumour | 28.17 | 10.74 | 8 | 182931 | 23 | 64315770 |
Renal impairment | 28.13 | 10.74 | 246 | 182693 | 134771 | 64181022 |
Cardiac disorder | 28.05 | 10.74 | 74 | 182865 | 55742 | 64260051 |
Apraxia | 28.03 | 10.74 | 35 | 182904 | 2460 | 64313333 |
Oligoasthenozoospermia | 27.89 | 10.74 | 7 | 182932 | 10 | 64315783 |
Oedema | 27.85 | 10.74 | 150 | 182789 | 91785 | 64224008 |
Balance disorder | 27.83 | 10.74 | 362 | 182577 | 83564 | 64232229 |
Motor dysfunction | 27.71 | 10.74 | 83 | 182856 | 11290 | 64304503 |
Pericarditis | 27.69 | 10.74 | 88 | 182851 | 62428 | 64253365 |
Pneumatosis | 27.63 | 10.74 | 21 | 182918 | 795 | 64314998 |
Injection site warmth | 27.56 | 10.74 | 3 | 182936 | 13459 | 64302334 |
Sneezing | 27.47 | 10.74 | 5 | 182934 | 15246 | 64300547 |
Psychotic behaviour | 27.40 | 10.74 | 23 | 182916 | 1006 | 64314787 |
Lymphocyte count increased | 27.37 | 10.74 | 50 | 182889 | 4925 | 64310868 |
Subileus | 27.35 | 10.74 | 50 | 182889 | 4927 | 64310866 |
Surgery | 27.13 | 10.74 | 24 | 182915 | 28189 | 64287604 |
Suspected suicide attempt | 27.02 | 10.74 | 14 | 182925 | 265 | 64315528 |
Hypertelorism | 26.89 | 10.74 | 11 | 182928 | 117 | 64315676 |
Developmental coordination disorder | 26.78 | 10.74 | 6 | 182933 | 3 | 64315790 |
Injection site haemorrhage | 26.72 | 10.74 | 18 | 182921 | 24260 | 64291533 |
Amenorrhoea | 26.68 | 10.74 | 58 | 182881 | 6481 | 64309312 |
Simple partial seizures | 26.62 | 10.74 | 19 | 182920 | 652 | 64315141 |
Blood triglycerides increased | 26.50 | 10.74 | 115 | 182824 | 18751 | 64297042 |
Incontinence | 26.50 | 10.74 | 85 | 182854 | 11996 | 64303797 |
Eosinophil count decreased | 26.34 | 10.74 | 35 | 182904 | 2617 | 64313176 |
Systemic inflammatory response syndrome | 26.18 | 10.74 | 76 | 182863 | 10159 | 64305634 |
Haemorrhoids | 26.14 | 10.74 | 18 | 182921 | 23983 | 64291810 |
Aspiration | 26.12 | 10.74 | 106 | 182833 | 16779 | 64299014 |
Device related infection | 26.06 | 10.74 | 29 | 182910 | 30597 | 64285196 |
Device issue | 26.00 | 10.74 | 16 | 182923 | 22632 | 64293161 |
Presyncope | 25.92 | 10.74 | 37 | 182902 | 35052 | 64280741 |
Myoglobinuria | 25.91 | 10.74 | 22 | 182917 | 978 | 64314815 |
Hypothyroidism | 25.88 | 10.74 | 200 | 182739 | 40257 | 64275536 |
Post-injection delirium sedation syndrome | 25.80 | 10.74 | 17 | 182922 | 511 | 64315282 |
Vomiting | 25.60 | 10.74 | 1290 | 181649 | 549827 | 63765966 |
Renal fusion anomaly | 25.59 | 10.74 | 6 | 182933 | 5 | 64315788 |
Reflexes abnormal | 25.58 | 10.74 | 20 | 182919 | 790 | 64315003 |
Heart rate irregular | 25.55 | 10.74 | 24 | 182915 | 27389 | 64288404 |
Niemann-Pick disease | 25.41 | 10.74 | 8 | 182931 | 36 | 64315757 |
Ulcer | 25.36 | 10.74 | 17 | 182922 | 22973 | 64292820 |
Blood osmolarity increased | 25.08 | 10.74 | 17 | 182922 | 536 | 64315257 |
Respiratory acidosis | 25.04 | 10.74 | 73 | 182866 | 9782 | 64306011 |
Accidental overdose | 24.97 | 10.74 | 172 | 182767 | 33385 | 64282408 |
Neoplasm malignant | 24.97 | 10.74 | 20 | 182919 | 24668 | 64291125 |
Glycosuria | 24.76 | 10.74 | 30 | 182909 | 2044 | 64313749 |
Eye pain | 24.73 | 10.74 | 32 | 182907 | 31593 | 64284200 |
Failure to suspend medication | 24.69 | 10.74 | 15 | 182924 | 390 | 64315403 |
Injection site rash | 24.68 | 10.74 | 7 | 182932 | 15735 | 64300058 |
Second primary malignancy | 24.63 | 10.74 | 3 | 182936 | 12334 | 64303459 |
Hirsutism | 24.38 | 10.74 | 21 | 182918 | 952 | 64314841 |
Hypotelorism of orbit | 24.34 | 10.74 | 5 | 182934 | 0 | 64315793 |
Decreased gait velocity | 24.26 | 10.74 | 11 | 182928 | 153 | 64315640 |
Ammonia abnormal | 24.20 | 10.74 | 11 | 182928 | 154 | 64315639 |
Self-injurious ideation | 24.10 | 10.74 | 37 | 182902 | 3160 | 64312633 |
Blood loss anaemia | 24.08 | 10.74 | 5 | 182934 | 13887 | 64301906 |
Angina unstable | 24.03 | 10.74 | 7 | 182932 | 15460 | 64300333 |
Blood urine present | 23.93 | 10.74 | 11 | 182928 | 18329 | 64297464 |
Rash pruritic | 23.91 | 10.74 | 83 | 182856 | 57321 | 64258472 |
Sinus disorder | 23.90 | 10.74 | 9 | 182930 | 16899 | 64298894 |
Lactate pyruvate ratio increased | 23.82 | 10.74 | 9 | 182930 | 76 | 64315717 |
Productive cough | 23.54 | 10.74 | 117 | 182822 | 73086 | 64242707 |
Blood pressure diastolic abnormal | 23.54 | 10.74 | 3 | 182936 | 11914 | 64303879 |
Medication overuse headache | 23.44 | 10.74 | 18 | 182921 | 692 | 64315101 |
Transplant rejection | 23.40 | 10.74 | 10 | 182929 | 17391 | 64298402 |
Candida infection | 23.34 | 10.74 | 33 | 182906 | 31386 | 64284407 |
Aminoaciduria | 23.26 | 10.74 | 12 | 182927 | 225 | 64315568 |
Gastric ulcer | 23.22 | 10.74 | 31 | 182908 | 30203 | 64285590 |
Drug dependence | 23.19 | 10.74 | 168 | 182771 | 33144 | 64282649 |
Neuralgia | 23.16 | 10.74 | 24 | 182915 | 26160 | 64289633 |
Hernia | 23.16 | 10.74 | 5 | 182934 | 13513 | 64302280 |
Brain malformation | 23.11 | 10.74 | 8 | 182931 | 51 | 64315742 |
Sarcopenia | 23.08 | 10.74 | 14 | 182925 | 363 | 64315430 |
Dyscalculia | 22.97 | 10.74 | 8 | 182931 | 52 | 64315741 |
Dissociation | 22.91 | 10.74 | 35 | 182904 | 2976 | 64312817 |
Ultrasound ovary abnormal | 22.76 | 10.74 | 9 | 182930 | 87 | 64315706 |
Reduced facial expression | 22.72 | 10.74 | 29 | 182910 | 2084 | 64313709 |
Clonus | 22.72 | 10.74 | 52 | 182887 | 6015 | 64309778 |
Dyspepsia | 22.72 | 10.74 | 134 | 182805 | 80178 | 64235615 |
Product administered to patient of inappropriate age | 22.53 | 10.74 | 44 | 182895 | 4557 | 64311236 |
Nephrocalcinosis | 22.30 | 10.74 | 23 | 182916 | 1311 | 64314482 |
Saccadic eye movement | 22.19 | 10.74 | 10 | 182929 | 137 | 64315656 |
Blood osmolarity decreased | 22.19 | 10.74 | 22 | 182917 | 1196 | 64314597 |
Lymphangioleiomyomatosis | 22.06 | 10.74 | 10 | 182929 | 139 | 64315654 |
Squamous cell carcinoma | 22.06 | 10.74 | 6 | 182933 | 13863 | 64301930 |
Crying | 22.05 | 10.74 | 114 | 182825 | 19976 | 64295817 |
Dry eye | 22.04 | 10.74 | 30 | 182909 | 28989 | 64286804 |
Postural tremor | 22.02 | 10.74 | 16 | 182923 | 565 | 64315228 |
Oral candidiasis | 22.01 | 10.74 | 20 | 182919 | 23192 | 64292601 |
Microstomia | 22.00 | 10.74 | 5 | 182934 | 3 | 64315790 |
Full blood count decreased | 21.97 | 10.74 | 19 | 182920 | 22563 | 64293230 |
Blood sodium increased | 21.95 | 10.74 | 42 | 182897 | 4284 | 64311509 |
Ageusia | 21.92 | 10.74 | 6 | 182933 | 13807 | 64301986 |
Throat tightness | 21.91 | 10.74 | 20 | 182919 | 23140 | 64292653 |
Asthma | 21.88 | 10.74 | 169 | 182770 | 95056 | 64220737 |
Therapy interrupted | 21.85 | 10.74 | 15 | 182924 | 20021 | 64295772 |
Faecaloma | 21.84 | 10.74 | 69 | 182870 | 9659 | 64306134 |
Pneumothorax | 21.80 | 10.74 | 22 | 182917 | 24276 | 64291517 |
Hiatus hernia | 21.69 | 10.74 | 15 | 182924 | 19942 | 64295851 |
Muscle twitching | 21.68 | 10.74 | 109 | 182830 | 18889 | 64296904 |
Skin disorder | 21.65 | 10.74 | 28 | 182911 | 27652 | 64288141 |
Hyperexplexia | 21.63 | 10.74 | 7 | 182932 | 35 | 64315758 |
Hip fracture | 21.62 | 10.74 | 27 | 182912 | 27072 | 64288721 |
Asphyxia | 21.61 | 10.74 | 68 | 182871 | 9498 | 64306295 |
Metabolic disorder | 21.49 | 10.74 | 59 | 182880 | 7638 | 64308155 |
Hyperphagia | 21.48 | 10.74 | 29 | 182910 | 2202 | 64313591 |
Dysphonia | 21.45 | 10.74 | 64 | 182875 | 46318 | 64269475 |
Chronic kidney disease | 21.36 | 10.74 | 88 | 182851 | 57831 | 64257962 |
Frontotemporal dementia | 21.16 | 10.74 | 15 | 182924 | 509 | 64315284 |
Galactorrhoea | 21.16 | 10.74 | 35 | 182904 | 3184 | 64312609 |
Oral herpes | 21.11 | 10.74 | 19 | 182920 | 22133 | 64293660 |
Bladder cancer | 21.11 | 10.74 | 3 | 182936 | 10971 | 64304822 |
Gallbladder disorder | 21.03 | 10.74 | 11 | 182928 | 17019 | 64298774 |
Irregular sleep phase | 21.03 | 10.74 | 8 | 182931 | 69 | 64315724 |
Developmental regression | 21.01 | 10.74 | 7 | 182932 | 39 | 64315754 |
IVth nerve disorder | 20.94 | 10.74 | 6 | 182933 | 18 | 64315775 |
Necrotising colitis | 20.91 | 10.74 | 19 | 182920 | 925 | 64314868 |
Bronchiectasis | 20.89 | 10.74 | 7 | 182932 | 14133 | 64301660 |
Intervertebral disc protrusion | 20.87 | 10.74 | 16 | 182923 | 20175 | 64295618 |
Condition aggravated | 20.79 | 10.74 | 1272 | 181667 | 371154 | 63944639 |
Illogical thinking | 20.73 | 10.74 | 8 | 182931 | 72 | 64315721 |
Adrenal insufficiency | 20.59 | 10.74 | 20 | 182919 | 22467 | 64293326 |
Urine amphetamine positive | 20.54 | 10.74 | 8 | 182931 | 74 | 64315719 |
Hypophosphataemic osteomalacia | 20.50 | 10.74 | 12 | 182927 | 291 | 64315502 |
Hypersomnia | 20.35 | 10.74 | 110 | 182829 | 19607 | 64296186 |
Angioedema | 20.35 | 10.74 | 98 | 182841 | 61723 | 64254070 |
Paraesthesia oral | 20.29 | 10.74 | 6 | 182933 | 13125 | 64302668 |
Therapeutic product ineffective for unapproved indication | 20.26 | 10.74 | 9 | 182930 | 119 | 64315674 |
Therapeutic response changed | 20.24 | 10.74 | 19 | 182920 | 965 | 64314828 |
Movement disorder | 20.23 | 10.74 | 119 | 182820 | 21881 | 64293912 |
Hostility | 20.21 | 10.74 | 28 | 182911 | 2179 | 64313614 |
Antisocial behaviour | 20.20 | 10.74 | 15 | 182924 | 548 | 64315245 |
Cholelithiasis | 20.19 | 10.74 | 64 | 182875 | 45442 | 64270351 |
Nodule | 20.16 | 10.74 | 13 | 182926 | 17934 | 64297859 |
Hepatic cirrhosis | 20.16 | 10.74 | 27 | 182912 | 26271 | 64289522 |
Haemoglobin decreased | 20.15 | 10.74 | 411 | 182528 | 194652 | 64121141 |
Gliosis | 20.11 | 10.74 | 13 | 182926 | 378 | 64315415 |
Disturbance in social behaviour | 20.05 | 10.74 | 38 | 182901 | 3849 | 64311944 |
Monocytosis | 19.99 | 10.74 | 16 | 182923 | 654 | 64315139 |
Coagulopathy | 19.98 | 10.74 | 157 | 182782 | 31763 | 64284030 |
Sputum discoloured | 19.97 | 10.74 | 13 | 182926 | 17843 | 64297950 |
Gamma-glutamyltransferase increased | 19.94 | 10.74 | 218 | 182721 | 48292 | 64267501 |
Carpal tunnel syndrome | 19.88 | 10.74 | 10 | 182929 | 15818 | 64299975 |
Clostridium difficile colitis | 19.82 | 10.74 | 29 | 182910 | 27194 | 64288599 |
Drug monitoring procedure incorrectly performed | 19.78 | 10.74 | 13 | 182926 | 389 | 64315404 |
Feeling of despair | 19.75 | 10.74 | 30 | 182909 | 2538 | 64313255 |
Gout | 19.66 | 10.74 | 19 | 182920 | 21394 | 64294399 |
Febrile bone marrow aplasia | 19.62 | 10.74 | 4 | 182935 | 11251 | 64304542 |
Muscular weakness | 19.60 | 10.74 | 249 | 182690 | 127089 | 64188704 |
Pancreatic carcinoma | 19.57 | 10.74 | 3 | 182936 | 10370 | 64305423 |
Dysphagia | 19.55 | 10.74 | 418 | 182521 | 106394 | 64209399 |
Diffuse large B-cell lymphoma | 19.54 | 10.74 | 3 | 182936 | 10358 | 64305435 |
Deja vu | 19.54 | 10.74 | 7 | 182932 | 50 | 64315743 |
Intelligence test abnormal | 19.47 | 10.74 | 4 | 182935 | 0 | 64315793 |
Gaucher's disease | 19.47 | 10.74 | 4 | 182935 | 0 | 64315793 |
Hypocarnitinaemia | 19.47 | 10.74 | 4 | 182935 | 0 | 64315793 |
Congenital nose malformation | 19.47 | 10.74 | 4 | 182935 | 0 | 64315793 |
Alpers disease | 19.47 | 10.74 | 4 | 182935 | 0 | 64315793 |
Injection site urticaria | 19.43 | 10.74 | 4 | 182935 | 11177 | 64304616 |
Musculoskeletal discomfort | 19.39 | 10.74 | 11 | 182928 | 16266 | 64299527 |
Skin cancer | 19.39 | 10.74 | 5 | 182934 | 11969 | 64303824 |
Hepatitis C virus test positive | 19.38 | 10.74 | 12 | 182927 | 323 | 64315470 |
Colon cancer | 19.36 | 10.74 | 6 | 182933 | 12733 | 64303060 |
Anxiety | 19.36 | 10.74 | 730 | 182209 | 201919 | 64113874 |
Joint effusion | 19.34 | 10.74 | 7 | 182932 | 13466 | 64302327 |
Oral pain | 19.33 | 10.74 | 30 | 182909 | 27463 | 64288330 |
Stress | 19.32 | 10.74 | 97 | 182842 | 60437 | 64255356 |
Middle insomnia | 19.26 | 10.74 | 80 | 182859 | 12797 | 64302996 |
Hereditary ataxia | 19.24 | 10.74 | 6 | 182933 | 26 | 64315767 |
Febrile convulsion | 19.23 | 10.74 | 17 | 182922 | 798 | 64314995 |
Pectus excavatum | 19.22 | 10.74 | 5 | 182934 | 9 | 64315784 |
Anisometropia | 19.22 | 10.74 | 5 | 182934 | 9 | 64315784 |
Basilar artery occlusion | 19.22 | 10.74 | 10 | 182929 | 191 | 64315602 |
Bradypnoea | 19.08 | 10.74 | 44 | 182895 | 5115 | 64310678 |
Procalcitonin increased | 19.02 | 10.74 | 29 | 182910 | 2462 | 64313331 |
Nephrolithiasis | 18.99 | 10.74 | 62 | 182877 | 43621 | 64272172 |
Patient isolation | 18.96 | 10.74 | 7 | 182932 | 55 | 64315738 |
Cataplexy | 18.95 | 10.74 | 17 | 182922 | 814 | 64314979 |
High arched palate | 18.88 | 10.74 | 5 | 182934 | 10 | 64315783 |
Neck pain | 18.85 | 10.74 | 100 | 182839 | 61433 | 64254360 |
Neglect of personal appearance | 18.84 | 10.74 | 9 | 182930 | 142 | 64315651 |
Neutrophil Pelger-Huet anomaly present | 18.81 | 10.74 | 12 | 182927 | 341 | 64315452 |
Lymphoma | 18.76 | 10.74 | 8 | 182931 | 13933 | 64301860 |
Sleep disorder | 18.74 | 10.74 | 255 | 182684 | 59454 | 64256339 |
Gastroenteritis viral | 18.71 | 10.74 | 17 | 182922 | 19712 | 64296081 |
Tooth infection | 18.68 | 10.74 | 9 | 182930 | 14592 | 64301201 |
Cerebral ventricle dilatation | 18.66 | 10.74 | 18 | 182921 | 946 | 64314847 |
Metastases to lung | 18.64 | 10.74 | 10 | 182929 | 15254 | 64300539 |
Multiple congenital abnormalities | 18.62 | 10.74 | 8 | 182931 | 97 | 64315696 |
Swollen tongue | 18.60 | 10.74 | 45 | 182894 | 34909 | 64280884 |
Dyspraxia | 18.60 | 10.74 | 11 | 182928 | 272 | 64315521 |
Mixed delusion | 18.56 | 10.74 | 5 | 182934 | 11 | 64315782 |
Low set ears | 18.55 | 10.74 | 8 | 182931 | 98 | 64315695 |
School refusal | 18.54 | 10.74 | 6 | 182933 | 30 | 64315763 |
Eye movement disorder | 18.53 | 10.74 | 53 | 182886 | 7026 | 64308767 |
Intervertebral disc degeneration | 18.52 | 10.74 | 7 | 182932 | 13113 | 64302680 |
Blood potassium decreased | 18.50 | 10.74 | 56 | 182883 | 40343 | 64275450 |
COVID-19 pneumonia | 18.48 | 10.74 | 12 | 182927 | 16492 | 64299301 |
Gene mutation | 18.45 | 10.74 | 26 | 182913 | 2056 | 64313737 |
Red blood cell sedimentation rate increased | 18.43 | 10.74 | 38 | 182901 | 31197 | 64284596 |
Illness | 18.42 | 10.74 | 21 | 182918 | 21917 | 64293876 |
Tendon rupture | 18.41 | 10.74 | 4 | 182935 | 10763 | 64305030 |
Blood gases abnormal | 18.36 | 10.74 | 18 | 182921 | 965 | 64314828 |
Trismus | 18.34 | 10.74 | 42 | 182897 | 4859 | 64310934 |
Transient ischaemic attack | 18.32 | 10.74 | 64 | 182875 | 44118 | 64271675 |
Disorganised speech | 18.30 | 10.74 | 23 | 182916 | 1627 | 64314166 |
Blood creatinine increased | 18.22 | 10.74 | 273 | 182666 | 135509 | 64180284 |
Inhibitory drug interaction | 18.14 | 10.74 | 35 | 182904 | 3592 | 64312201 |
Therapeutic product effective for unapproved indication | 18.13 | 10.74 | 8 | 182931 | 104 | 64315689 |
Device difficult to use | 18.11 | 10.74 | 3 | 182936 | 9795 | 64305998 |
Malignant catatonia | 18.09 | 10.74 | 12 | 182927 | 365 | 64315428 |
Blood urea decreased | 18.05 | 10.74 | 30 | 182909 | 2741 | 64313052 |
Atrial flutter | 18.02 | 10.74 | 17 | 182922 | 19363 | 64296430 |
Coma hepatic | 17.92 | 10.74 | 18 | 182921 | 994 | 64314799 |
Enteritis | 17.80 | 10.74 | 6 | 182933 | 12071 | 64303722 |
Osmolar gap increased | 17.78 | 10.74 | 6 | 182933 | 35 | 64315758 |
Immunodeficiency | 17.68 | 10.74 | 12 | 182927 | 16112 | 64299681 |
Enterocolitis | 17.67 | 10.74 | 6 | 182933 | 12012 | 64303781 |
White blood cell count decreased | 17.66 | 10.74 | 579 | 182360 | 157258 | 64158535 |
Sedation complication | 17.63 | 10.74 | 67 | 182872 | 10287 | 64305506 |
Epileptic aura | 17.58 | 10.74 | 7 | 182932 | 69 | 64315724 |
Hepatic steatosis | 17.51 | 10.74 | 149 | 182790 | 30858 | 64284935 |
Oxygen saturation decreased | 17.47 | 10.74 | 207 | 182732 | 106969 | 64208824 |
Sciatica | 17.45 | 10.74 | 19 | 182920 | 20245 | 64295548 |
Talipes | 17.41 | 10.74 | 8 | 182931 | 115 | 64315678 |
Neutrophilia | 17.40 | 10.74 | 50 | 182889 | 6644 | 64309149 |
Personal relationship issue | 17.38 | 10.74 | 9 | 182930 | 170 | 64315623 |
Circadian rhythm sleep disorder | 17.37 | 10.74 | 14 | 182925 | 578 | 64315215 |
Wrong schedule | 17.29 | 10.74 | 11 | 182928 | 311 | 64315482 |
Blood pyruvic acid increased | 17.24 | 10.74 | 4 | 182935 | 3 | 64315790 |
Camptodactyly congenital | 17.24 | 10.74 | 4 | 182935 | 3 | 64315790 |
Lipids | 17.21 | 10.74 | 5 | 182934 | 16 | 64315777 |
Emotional disorder of childhood | 17.21 | 10.74 | 5 | 182934 | 16 | 64315777 |
Shock | 17.19 | 10.74 | 175 | 182764 | 38065 | 64277728 |
Tooth disorder | 17.17 | 10.74 | 23 | 182916 | 22379 | 64293414 |
Lacrimation increased | 17.17 | 10.74 | 16 | 182923 | 18330 | 64297463 |
Laboratory test abnormal | 17.16 | 10.74 | 26 | 182913 | 24037 | 64291756 |
Ear pain | 17.13 | 10.74 | 28 | 182911 | 25108 | 64290685 |
Angular cheilitis | 17.13 | 10.74 | 13 | 182926 | 491 | 64315302 |
Haematuria | 17.04 | 10.74 | 101 | 182838 | 60370 | 64255423 |
Hypotonia neonatal | 16.98 | 10.74 | 7 | 182932 | 76 | 64315717 |
Aptyalism | 16.97 | 10.74 | 15 | 182924 | 704 | 64315089 |
Poor venous access | 16.91 | 10.74 | 7 | 182932 | 12410 | 64303383 |
Mucosal erosion | 16.91 | 10.74 | 24 | 182915 | 1910 | 64313883 |
Burning sensation | 16.77 | 10.74 | 78 | 182861 | 49586 | 64266207 |
Myelodysplastic syndrome | 16.75 | 10.74 | 33 | 182906 | 27546 | 64288247 |
Nephropathy toxic | 16.72 | 10.74 | 15 | 182924 | 17499 | 64298294 |
Parkinsonian gait | 16.71 | 10.74 | 16 | 182923 | 833 | 64314960 |
Hyperhomocysteinaemia | 16.63 | 10.74 | 12 | 182927 | 419 | 64315374 |
Cardiac steatosis | 16.61 | 10.74 | 6 | 182933 | 44 | 64315749 |
Hepatotoxicity | 16.61 | 10.74 | 180 | 182759 | 39782 | 64276011 |
Tooth malformation | 16.59 | 10.74 | 7 | 182932 | 81 | 64315712 |
Venoocclusive liver disease | 16.57 | 10.74 | 4 | 182935 | 10011 | 64305782 |
Lacrimal gland enlargement | 16.55 | 10.74 | 5 | 182934 | 19 | 64315774 |
Clinodactyly | 16.55 | 10.74 | 5 | 182934 | 19 | 64315774 |
Dermatitis | 16.55 | 10.74 | 16 | 182923 | 18013 | 64297780 |
Compensatory sweating | 16.50 | 10.74 | 6 | 182933 | 45 | 64315748 |
Feeling cold | 16.49 | 10.74 | 26 | 182913 | 23652 | 64292141 |
Shock haemorrhagic | 16.49 | 10.74 | 14 | 182925 | 16777 | 64299016 |
Water intoxication | 16.43 | 10.74 | 15 | 182924 | 735 | 64315058 |
Haematotoxicity | 16.42 | 10.74 | 8 | 182931 | 12888 | 64302905 |
Procedural pain | 16.40 | 10.74 | 12 | 182927 | 15496 | 64300297 |
Brain death | 16.39 | 10.74 | 40 | 182899 | 4821 | 64310972 |
Blood pressure systolic abnormal | 16.39 | 10.74 | 4 | 182935 | 9938 | 64305855 |
Influenza like illness | 16.38 | 10.74 | 105 | 182834 | 61597 | 64254196 |
Hypercalcaemia | 16.29 | 10.74 | 41 | 182898 | 31375 | 64284418 |
Congenital foot malformation | 16.24 | 10.74 | 4 | 182935 | 5 | 64315788 |
Rotator cuff syndrome | 16.21 | 10.74 | 7 | 182932 | 12100 | 64303693 |
Type 1 diabetes mellitus | 16.20 | 10.74 | 44 | 182895 | 5661 | 64310132 |
Influenza B virus test positive | 16.14 | 10.74 | 11 | 182928 | 350 | 64315443 |
Prothrombin time shortened | 16.14 | 10.74 | 29 | 182910 | 2820 | 64312973 |
Torticollis | 16.14 | 10.74 | 25 | 182914 | 2152 | 64313641 |
Posterior reversible encephalopathy syndrome | 16.13 | 10.74 | 116 | 182823 | 22830 | 64292963 |
Dermatitis contact | 16.11 | 10.74 | 3 | 182936 | 8997 | 64306796 |
Deep vein thrombosis | 16.07 | 10.74 | 206 | 182733 | 104976 | 64210817 |
Disease recurrence | 16.03 | 10.74 | 148 | 182791 | 31362 | 64284431 |
Conversion disorder | 16.03 | 10.74 | 22 | 182917 | 1697 | 64314096 |
Gender dysphoria | 15.95 | 10.74 | 6 | 182933 | 50 | 64315743 |
Mucosal ulceration | 15.95 | 10.74 | 22 | 182917 | 1705 | 64314088 |
Mass | 15.92 | 10.74 | 12 | 182927 | 15264 | 64300529 |
Acquired macroglossia | 15.92 | 10.74 | 9 | 182930 | 204 | 64315589 |
Osteomyelitis | 15.91 | 10.74 | 34 | 182905 | 27553 | 64288240 |
Diplopia | 15.85 | 10.74 | 130 | 182809 | 26635 | 64289158 |
Opisthotonus | 15.84 | 10.74 | 14 | 182925 | 657 | 64315136 |
Polyarthritis | 15.84 | 10.74 | 4 | 182935 | 9711 | 64306082 |
Mastication disorder | 15.82 | 10.74 | 26 | 182913 | 2353 | 64313440 |
Pneumonia fungal | 15.80 | 10.74 | 3 | 182936 | 8874 | 64306919 |
Spinal fracture | 15.72 | 10.74 | 12 | 182927 | 15162 | 64300631 |
Anaemia macrocytic | 15.70 | 10.74 | 37 | 182902 | 4361 | 64311432 |
Heat stroke | 15.69 | 10.74 | 20 | 182919 | 1435 | 64314358 |
Rebound psychosis | 15.65 | 10.74 | 8 | 182931 | 147 | 64315646 |
Pyromania | 15.62 | 10.74 | 5 | 182934 | 24 | 64315769 |
Glaucoma | 15.61 | 10.74 | 14 | 182925 | 16334 | 64299459 |
Tooth abscess | 15.55 | 10.74 | 10 | 182929 | 13816 | 64301977 |
Cardiogenic shock | 15.54 | 10.74 | 44 | 182895 | 32383 | 64283410 |
Graft versus host disease | 15.53 | 10.74 | 10 | 182929 | 13803 | 64301990 |
MELAS syndrome | 15.51 | 10.74 | 8 | 182931 | 150 | 64315643 |
Duodenal ulcer | 15.49 | 10.74 | 11 | 182928 | 14424 | 64301369 |
Pulmonary eosinophilia | 15.48 | 10.74 | 13 | 182926 | 569 | 64315224 |
Polyserositis | 15.43 | 10.74 | 12 | 182927 | 470 | 64315323 |
Pancreatitis haemorrhagic | 15.42 | 10.74 | 13 | 182926 | 572 | 64315221 |
Hyperreflexia | 15.41 | 10.74 | 50 | 182889 | 7098 | 64308695 |
Intention tremor | 15.40 | 10.74 | 14 | 182925 | 682 | 64315111 |
Patent ductus arteriosus | 15.40 | 10.74 | 7 | 182932 | 98 | 64315695 |
Idiosyncratic drug reaction | 15.40 | 10.74 | 18 | 182921 | 1181 | 64314612 |
Alcohol abuse | 15.39 | 10.74 | 39 | 182900 | 4813 | 64310980 |
Extensor plantar response | 15.31 | 10.74 | 21 | 182918 | 1619 | 64314174 |
Sinus tachycardia | 15.29 | 10.74 | 149 | 182790 | 32039 | 64283754 |
Nose deformity | 15.27 | 10.74 | 8 | 182931 | 155 | 64315638 |
Bone disorder | 15.24 | 10.74 | 15 | 182924 | 16744 | 64299049 |
Snoring | 15.23 | 10.74 | 38 | 182901 | 4644 | 64311149 |
Gastroenteritis | 15.23 | 10.74 | 39 | 182900 | 29672 | 64286121 |
Personality disorder | 15.08 | 10.74 | 38 | 182901 | 4673 | 64311120 |
Diabetic hyperosmolar coma | 15.06 | 10.74 | 14 | 182925 | 702 | 64315091 |
Rebound effect | 15.05 | 10.74 | 39 | 182900 | 4878 | 64310915 |
Amino acid level increased | 15.04 | 10.74 | 13 | 182926 | 592 | 64315201 |
Device dislocation | 14.99 | 10.74 | 23 | 182916 | 21155 | 64294638 |
Psychomotor disadaptation syndrome | 14.99 | 10.74 | 5 | 182934 | 28 | 64315765 |
Brain injury | 14.97 | 10.74 | 62 | 182877 | 9903 | 64305890 |
Astigmatism | 14.97 | 10.74 | 17 | 182922 | 1081 | 64314712 |
Embolism | 14.97 | 10.74 | 8 | 182931 | 12227 | 64303566 |
Rotavirus infection | 14.89 | 10.74 | 13 | 182926 | 600 | 64315193 |
Cholangitis | 14.86 | 10.74 | 6 | 182933 | 10796 | 64304997 |
Electrocardiogram J wave abnormal | 14.78 | 10.74 | 4 | 182935 | 9 | 64315784 |
Congenital renal disorder | 14.78 | 10.74 | 4 | 182935 | 9 | 64315784 |
Clonic convulsion | 14.71 | 10.74 | 17 | 182922 | 1102 | 64314691 |
Back disorder | 14.66 | 10.74 | 5 | 182934 | 9985 | 64305808 |
Product administration error | 14.66 | 10.74 | 131 | 182808 | 27512 | 64288281 |
Sperm concentration decreased | 14.65 | 10.74 | 6 | 182933 | 64 | 64315729 |
Dissociative disorder | 14.62 | 10.74 | 11 | 182928 | 410 | 64315383 |
Urine sodium increased | 14.61 | 10.74 | 8 | 182931 | 170 | 64315623 |
Dacryoadenitis acquired | 14.60 | 10.74 | 3 | 182936 | 0 | 64315793 |
Diabetic encephalopathy | 14.60 | 10.74 | 3 | 182936 | 0 | 64315793 |
Nasopharyngeal reflux | 14.60 | 10.74 | 3 | 182936 | 0 | 64315793 |
3-hydroxyacetyl-coenzyme A dehydrogenase deficiency | 14.60 | 10.74 | 3 | 182936 | 0 | 64315793 |
Lisfranc fracture | 14.60 | 10.74 | 3 | 182936 | 0 | 64315793 |
Congenital scoliosis | 14.60 | 10.74 | 3 | 182936 | 0 | 64315793 |
Social (pragmatic) communication disorder | 14.60 | 10.74 | 3 | 182936 | 0 | 64315793 |
Congenital eyelid malformation | 14.60 | 10.74 | 3 | 182936 | 0 | 64315793 |
Near drowning | 14.56 | 10.74 | 5 | 182934 | 31 | 64315762 |
Slow response to stimuli | 14.55 | 10.74 | 20 | 182919 | 1545 | 64314248 |
Poor personal hygiene | 14.53 | 10.74 | 12 | 182927 | 513 | 64315280 |
Erythema multiforme | 14.48 | 10.74 | 85 | 182854 | 15616 | 64300177 |
Feminisation acquired | 14.42 | 10.74 | 5 | 182934 | 32 | 64315761 |
Glioblastoma multiforme | 14.40 | 10.74 | 17 | 182922 | 1127 | 64314666 |
Posturing | 14.36 | 10.74 | 16 | 182923 | 996 | 64314797 |
Hyporeflexia | 14.28 | 10.74 | 30 | 182909 | 3274 | 64312519 |
Abulia | 14.24 | 10.74 | 15 | 182924 | 876 | 64314917 |
Cerebral arteriosclerosis | 14.24 | 10.74 | 14 | 182925 | 753 | 64315040 |
Diverticulum | 14.24 | 10.74 | 10 | 182929 | 13188 | 64302605 |
Pathogen resistance | 14.21 | 10.74 | 9 | 182930 | 12534 | 64303259 |
Pneumonia bacterial | 14.20 | 10.74 | 13 | 182926 | 15022 | 64300771 |
Ankylosing spondylitis | 14.20 | 10.74 | 3 | 182936 | 8231 | 64307562 |
Delusional perception | 14.20 | 10.74 | 10 | 182929 | 336 | 64315457 |
Rickets | 14.17 | 10.74 | 6 | 182933 | 70 | 64315723 |
Fanconi syndrome acquired | 14.17 | 10.74 | 25 | 182914 | 2396 | 64313397 |
Fistula | 14.13 | 10.74 | 5 | 182934 | 9756 | 64306037 |
Retinitis pigmentosa | 14.13 | 10.74 | 7 | 182932 | 120 | 64315673 |
Body temperature decreased | 14.10 | 10.74 | 33 | 182906 | 25895 | 64289898 |
Hypokalaemia | 14.07 | 10.74 | 252 | 182687 | 121651 | 64194142 |
Eosinophil count increased | 14.07 | 10.74 | 78 | 182861 | 14034 | 64301759 |
Myelosuppression | 14.06 | 10.74 | 29 | 182910 | 23801 | 64291992 |
Insomnia | 14.04 | 10.74 | 691 | 182248 | 197145 | 64118648 |
Bronchospasm | 14.00 | 10.74 | 25 | 182914 | 21657 | 64294136 |
Opsoclonus myoclonus | 13.97 | 10.74 | 8 | 182931 | 186 | 64315607 |
Locomotive syndrome | 13.96 | 10.74 | 4 | 182935 | 12 | 64315781 |
Amino acid metabolism disorder | 13.96 | 10.74 | 4 | 182935 | 12 | 64315781 |
Ketosis-prone diabetes mellitus | 13.96 | 10.74 | 4 | 182935 | 12 | 64315781 |
Abdominal distension | 13.93 | 10.74 | 190 | 182749 | 95804 | 64219989 |
Gingival atrophy | 13.88 | 10.74 | 6 | 182933 | 74 | 64315719 |
Renal tubular necrosis | 13.82 | 10.74 | 26 | 182913 | 22084 | 64293709 |
Anticoagulation drug level decreased | 13.77 | 10.74 | 7 | 182932 | 127 | 64315666 |
Drug eruption | 13.76 | 10.74 | 160 | 182779 | 35976 | 64279817 |
Unmasking of previously unidentified disease | 13.76 | 10.74 | 20 | 182919 | 1627 | 64314166 |
Derealisation | 13.74 | 10.74 | 19 | 182920 | 1476 | 64314317 |
False positive investigation result | 13.73 | 10.74 | 14 | 182925 | 787 | 64315006 |
Spinal compression fracture | 13.69 | 10.74 | 13 | 182926 | 14762 | 64301031 |
Musculoskeletal chest pain | 13.66 | 10.74 | 25 | 182914 | 21454 | 64294339 |
Small intestinal obstruction | 13.64 | 10.74 | 29 | 182910 | 23544 | 64292249 |
Staphylococcal infection | 13.57 | 10.74 | 86 | 182853 | 50592 | 64265201 |
Altered visual depth perception | 13.50 | 10.74 | 10 | 182929 | 364 | 64315429 |
Ehlers-Danlos syndrome | 13.48 | 10.74 | 7 | 182932 | 133 | 64315660 |
Visuospatial deficit | 13.47 | 10.74 | 5 | 182934 | 40 | 64315753 |
Polydipsia psychogenic | 13.45 | 10.74 | 8 | 182931 | 200 | 64315593 |
Gastrointestinal sounds abnormal | 13.40 | 10.74 | 37 | 182902 | 4806 | 64310987 |
Hyperdynamic left ventricle | 13.33 | 10.74 | 9 | 182930 | 282 | 64315511 |
SJS-TEN overlap | 13.33 | 10.74 | 11 | 182928 | 470 | 64315323 |
Escherichia infection | 13.31 | 10.74 | 14 | 182925 | 15154 | 64300639 |
Toothache | 13.31 | 10.74 | 18 | 182921 | 17441 | 64298352 |
Terminal insomnia | 13.27 | 10.74 | 15 | 182924 | 949 | 64314844 |
Wrong technique in product usage process | 13.25 | 10.74 | 119 | 182820 | 64855 | 64250938 |
Lower gastrointestinal haemorrhage | 13.23 | 10.74 | 12 | 182927 | 13927 | 64301866 |
Hypoacusis | 13.22 | 10.74 | 34 | 182905 | 25833 | 64289960 |
Factor XIII deficiency | 13.20 | 10.74 | 6 | 182933 | 84 | 64315709 |
Type 2 diabetes mellitus | 13.12 | 10.74 | 151 | 182788 | 33869 | 64281924 |
Urine calcium/creatinine ratio increased | 13.12 | 10.74 | 7 | 182932 | 141 | 64315652 |
Hypoventilation | 12.94 | 10.74 | 42 | 182897 | 5964 | 64309829 |
Accidental death | 12.94 | 10.74 | 31 | 182908 | 3694 | 64312099 |
Diabetic coma | 12.92 | 10.74 | 16 | 182923 | 1115 | 64314678 |
Precocious puberty | 12.92 | 10.74 | 9 | 182930 | 297 | 64315496 |
Tubo-ovarian abscess | 12.92 | 10.74 | 9 | 182930 | 297 | 64315496 |
Synovial cyst | 12.90 | 10.74 | 3 | 182936 | 7704 | 64308089 |
Gynaecomastia | 12.90 | 10.74 | 42 | 182897 | 5974 | 64309819 |
Lip erosion | 12.89 | 10.74 | 17 | 182922 | 1262 | 64314531 |
Lipids abnormal | 12.84 | 10.74 | 11 | 182928 | 495 | 64315298 |
Lip haemorrhage | 12.83 | 10.74 | 16 | 182923 | 1123 | 64314670 |
Skin irritation | 12.82 | 10.74 | 5 | 182934 | 9189 | 64306604 |
Squamous cell carcinoma of skin | 12.81 | 10.74 | 9 | 182930 | 11867 | 64303926 |
Ejaculation disorder | 12.80 | 10.74 | 11 | 182928 | 497 | 64315296 |
Acute psychosis | 12.79 | 10.74 | 31 | 182908 | 3721 | 64312072 |
Renal injury | 12.70 | 10.74 | 15 | 182924 | 15414 | 64300379 |
Hepatocellular carcinoma | 12.70 | 10.74 | 4 | 182935 | 8399 | 64307394 |
Epileptic encephalopathy | 12.68 | 10.74 | 10 | 182929 | 400 | 64315393 |
Drug screen false positive | 12.68 | 10.74 | 15 | 182924 | 997 | 64314796 |
Serositis | 12.57 | 10.74 | 13 | 182926 | 743 | 64315050 |
Coloboma | 12.53 | 10.74 | 3 | 182936 | 3 | 64315790 |
Delusional disorder, mixed type | 12.53 | 10.74 | 3 | 182936 | 3 | 64315790 |
Liver injury | 12.52 | 10.74 | 135 | 182804 | 29797 | 64285996 |
Coma blister | 12.52 | 10.74 | 8 | 182931 | 228 | 64315565 |
Cytotoxic oedema | 12.51 | 10.74 | 9 | 182930 | 313 | 64315480 |
Organising pneumonia | 12.50 | 10.74 | 5 | 182934 | 9050 | 64306743 |
Malignant melanoma | 12.50 | 10.74 | 11 | 182928 | 12953 | 64302840 |
Cardiovascular disorder | 12.49 | 10.74 | 16 | 182923 | 15865 | 64299928 |
Withdrawal catatonia | 12.48 | 10.74 | 7 | 182932 | 156 | 64315637 |
Cerebral palsy | 12.48 | 10.74 | 7 | 182932 | 156 | 64315637 |
Intraocular pressure increased | 12.46 | 10.74 | 4 | 182935 | 8298 | 64307495 |
Thermal burn | 12.45 | 10.74 | 41 | 182898 | 5865 | 64309928 |
Herbal interaction | 12.43 | 10.74 | 10 | 182929 | 412 | 64315381 |
Strabismus | 12.42 | 10.74 | 22 | 182917 | 2115 | 64313678 |
Wrong product administered | 12.37 | 10.74 | 49 | 182890 | 7671 | 64308122 |
Hyperpyrexia | 12.32 | 10.74 | 37 | 182902 | 5040 | 64310753 |
Cardiac failure acute | 12.31 | 10.74 | 17 | 182922 | 16327 | 64299466 |
Blunted affect | 12.30 | 10.74 | 10 | 182929 | 418 | 64315375 |
Hepatomegaly | 12.25 | 10.74 | 86 | 182853 | 16796 | 64298997 |
Pupillary reflex impaired | 12.25 | 10.74 | 27 | 182912 | 3046 | 64312747 |
Skin fissures | 12.23 | 10.74 | 7 | 182932 | 10299 | 64305494 |
Diverticulum intestinal | 12.20 | 10.74 | 3 | 182936 | 7417 | 64308376 |
Infertility male | 12.16 | 10.74 | 6 | 182933 | 102 | 64315691 |
Post procedural infection | 12.15 | 10.74 | 6 | 182933 | 9591 | 64306202 |
Compulsive sexual behaviour | 12.10 | 10.74 | 8 | 182931 | 242 | 64315551 |
Retinal function test abnormal | 12.07 | 10.74 | 3 | 182936 | 4 | 64315789 |
Intermittent explosive disorder | 12.07 | 10.74 | 3 | 182936 | 4 | 64315789 |
Coronary artery occlusion | 11.99 | 10.74 | 13 | 182926 | 13878 | 64301915 |
Large intestine polyp | 11.97 | 10.74 | 8 | 182931 | 10829 | 64304964 |
Substance-induced psychotic disorder | 11.89 | 10.74 | 25 | 182914 | 2730 | 64313063 |
Laryngeal stenosis | 11.87 | 10.74 | 13 | 182926 | 794 | 64314999 |
Hepatitis fulminant | 11.86 | 10.74 | 42 | 182897 | 6232 | 64309561 |
Upper-airway cough syndrome | 11.85 | 10.74 | 5 | 182934 | 8765 | 64307028 |
Cyst | 11.84 | 10.74 | 10 | 182929 | 12017 | 64303776 |
Sleep-related eating disorder | 11.84 | 10.74 | 12 | 182927 | 670 | 64315123 |
Respiratory syncytial virus infection | 11.83 | 10.74 | 3 | 182936 | 7265 | 64308528 |
Vasoplegia syndrome | 11.81 | 10.74 | 25 | 182914 | 2742 | 64313051 |
Immunosuppressant drug level increased | 11.81 | 10.74 | 3 | 182936 | 7256 | 64308537 |
Groin pain | 11.81 | 10.74 | 9 | 182930 | 11384 | 64304409 |
Blood insulin increased | 11.81 | 10.74 | 9 | 182930 | 342 | 64315451 |
Nipple disorder | 11.77 | 10.74 | 7 | 182932 | 175 | 64315618 |
Blood citric acid increased | 11.76 | 10.74 | 5 | 182934 | 59 | 64315734 |
Autoimmune hepatitis | 11.75 | 10.74 | 7 | 182932 | 10077 | 64305716 |
Attention-seeking behaviour | 11.75 | 10.74 | 6 | 182933 | 110 | 64315683 |
Spinal disorder | 11.75 | 10.74 | 5 | 182934 | 8717 | 64307076 |
Vascular encephalopathy | 11.68 | 10.74 | 11 | 182928 | 561 | 64315232 |
Waxy flexibility | 11.67 | 10.74 | 8 | 182931 | 257 | 64315536 |
Endocarditis | 11.67 | 10.74 | 6 | 182933 | 9372 | 64306421 |
Wound infection | 11.66 | 10.74 | 15 | 182924 | 14849 | 64300944 |
Drug-induced liver injury | 11.66 | 10.74 | 195 | 182744 | 47448 | 64268345 |
Non-cardiac chest pain | 11.65 | 10.74 | 5 | 182934 | 8675 | 64307118 |
Acute generalised exanthematous pustulosis | 11.64 | 10.74 | 74 | 182865 | 13984 | 64301809 |
Orthostatic tremor | 11.62 | 10.74 | 4 | 182935 | 25 | 64315768 |
Breast cancer metastatic | 11.59 | 10.74 | 3 | 182936 | 7166 | 64308627 |
Eclampsia | 11.56 | 10.74 | 7 | 182932 | 181 | 64315612 |
Haematuria traumatic | 11.49 | 10.74 | 7 | 182932 | 183 | 64315610 |
Osteoporosis | 11.48 | 10.74 | 71 | 182868 | 42009 | 64273784 |
Plasmodium falciparum infection | 11.47 | 10.74 | 5 | 182934 | 63 | 64315730 |
Post-acute COVID-19 syndrome | 11.47 | 10.74 | 5 | 182934 | 63 | 64315730 |
Ischaemic stroke | 11.42 | 10.74 | 43 | 182896 | 28992 | 64286801 |
Antidepressant drug level increased | 11.39 | 10.74 | 9 | 182930 | 361 | 64315432 |
Arthritis bacterial | 11.37 | 10.74 | 4 | 182935 | 7835 | 64307958 |
Illiteracy | 11.36 | 10.74 | 4 | 182935 | 27 | 64315766 |
Blood bicarbonate increased | 11.36 | 10.74 | 15 | 182924 | 1115 | 64314678 |
Hydronephrosis | 11.35 | 10.74 | 14 | 182925 | 14111 | 64301682 |
Pneumonia viral | 11.33 | 10.74 | 4 | 182935 | 7818 | 64307975 |
Parkinson's disease | 11.33 | 10.74 | 18 | 182921 | 1583 | 64314210 |
Rasmussen encephalitis | 11.33 | 10.74 | 3 | 182936 | 6 | 64315787 |
Ornithine transcarbamoylase deficiency | 11.33 | 10.74 | 3 | 182936 | 6 | 64315787 |
Congenital renal cyst | 11.33 | 10.74 | 3 | 182936 | 6 | 64315787 |
Drug half-life reduced | 11.33 | 10.74 | 3 | 182936 | 6 | 64315787 |
Neutrophil count decreased | 11.32 | 10.74 | 293 | 182646 | 76903 | 64238890 |
Urosepsis | 11.32 | 10.74 | 29 | 182910 | 22065 | 64293728 |
Genital erosion | 11.31 | 10.74 | 9 | 182930 | 365 | 64315428 |
Pulmonary thrombosis | 11.30 | 10.74 | 8 | 182931 | 10510 | 64305283 |
Monocyte count decreased | 11.27 | 10.74 | 25 | 182914 | 2832 | 64312961 |
Seasonal allergy | 11.24 | 10.74 | 10 | 182929 | 11716 | 64304077 |
Mitochondrial enzyme deficiency | 11.23 | 10.74 | 4 | 182935 | 28 | 64315765 |
Aphthous ulcer | 11.22 | 10.74 | 12 | 182927 | 12894 | 64302899 |
Colitis ulcerative | 11.22 | 10.74 | 31 | 182908 | 22997 | 64292796 |
Heparin-induced thrombocytopenia | 11.20 | 10.74 | 5 | 182934 | 8474 | 64307319 |
Restless legs syndrome | 11.16 | 10.74 | 85 | 182854 | 17031 | 64298762 |
Libido increased | 11.15 | 10.74 | 19 | 182920 | 1771 | 64314022 |
Pulmonary valve incompetence | 11.12 | 10.74 | 18 | 182921 | 1608 | 64314185 |
CSF white blood cell count positive | 11.11 | 10.74 | 4 | 182935 | 29 | 64315764 |
Echopraxia | 11.11 | 10.74 | 4 | 182935 | 29 | 64315764 |
Hyporesponsive to stimuli | 11.10 | 10.74 | 19 | 182920 | 1778 | 64314015 |
Megacolon | 11.08 | 10.74 | 26 | 182913 | 3056 | 64312737 |
Poriomania | 11.06 | 10.74 | 7 | 182932 | 196 | 64315597 |
Decreased activity | 11.05 | 10.74 | 45 | 182894 | 7135 | 64308658 |
Acute pulmonary oedema | 11.04 | 10.74 | 12 | 182927 | 12797 | 64302996 |
Frequent bowel movements | 11.03 | 10.74 | 22 | 182917 | 18283 | 64297510 |
Personality change | 11.03 | 10.74 | 51 | 182888 | 8542 | 64307251 |
Muscle tone disorder | 11.02 | 10.74 | 6 | 182933 | 126 | 64315667 |
Therapeutic product effect variable | 10.98 | 10.74 | 18 | 182921 | 1626 | 64314167 |
Internal haemorrhage | 10.97 | 10.74 | 4 | 182935 | 7663 | 64308130 |
Dermatitis bullous | 10.95 | 10.74 | 65 | 182874 | 11989 | 64303804 |
Dysuria | 10.94 | 10.74 | 72 | 182867 | 41985 | 64273808 |
Hypogonadism male | 10.94 | 10.74 | 6 | 182933 | 128 | 64315665 |
Multiple sclerosis relapse | 10.92 | 10.74 | 70 | 182869 | 41065 | 64274728 |
Alanine aminotransferase abnormal | 10.92 | 10.74 | 3 | 182936 | 6885 | 64308908 |
Coma acidotic | 10.89 | 10.74 | 6 | 182933 | 129 | 64315664 |
Sinus bradycardia | 10.89 | 10.74 | 106 | 182833 | 22787 | 64293006 |
Renal cancer | 10.89 | 10.74 | 3 | 182936 | 6872 | 64308921 |
Blood pressure diastolic decreased | 10.88 | 10.74 | 30 | 182909 | 22271 | 64293522 |
Intestinal pseudo-obstruction | 10.88 | 10.74 | 20 | 182919 | 1980 | 64313813 |
Pharyngeal oedema | 10.87 | 10.74 | 17 | 182922 | 15514 | 64300279 |
Hyperthyroidism | 10.83 | 10.74 | 22 | 182917 | 18157 | 64297636 |
Excessive masturbation | 10.81 | 10.74 | 5 | 182934 | 73 | 64315720 |
Myoglobin blood increased | 10.79 | 10.74 | 24 | 182915 | 2723 | 64313070 |
Gastrointestinal pain | 10.76 | 10.74 | 4 | 182935 | 7570 | 64308223 |
Cyclothymic disorder | 10.75 | 10.74 | 7 | 182932 | 206 | 64315587 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Foetal anticonvulsant syndrome | 147.75 | 26.17 | 41 | 836 | 0 | 83801 |
Congenital nose malformation | 57.43 | 26.17 | 16 | 861 | 0 | 83801 |
Low set ears | 41.33 | 26.17 | 15 | 862 | 20 | 83781 |
Dysmorphism | 35.74 | 26.17 | 32 | 845 | 402 | 83399 |
Cardiomegaly | 28.68 | 26.17 | 8 | 869 | 0 | 83801 |
Developmental delay | 27.36 | 26.17 | 14 | 863 | 61 | 83740 |
Source | Code | Description |
---|---|---|
ATC | N03AG01 | NERVOUS SYSTEM ANTIEPILEPTICS ANTIEPILEPTICS Fatty acid derivatives |
FDA PE | N0000008486 | Decreased Central Nervous System Disorganized Electrical Activity |
CHEBI has role | CHEBI:35477 | antimanic drugs |
CHEBI has role | CHEBI:35623 | anticonvulsants |
CHEBI has role | CHEBI:176497 | geroprotectors |
MeSH PA | D000927 | Anticonvulsants |
MeSH PA | D018692 | Antimanic Agents |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D002492 | Central Nervous System Depressants |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D018682 | GABA Agents |
MeSH PA | D018377 | Neurotransmitter Agents |
MeSH PA | D011619 | Psychotropic Drugs |
MeSH PA | D014149 | Tranquilizing Agents |
FDA EPC | N0000175751 | Mood Stabilizer |
FDA EPC | N0000175753 | Anti-epileptic Agent |
CHEBI has role | CHEBI:35471 | psychotropic drugs |
CHEBI has role | CHEBI:50905 | teratogeno |
CHEBI has role | CHEBI:61115 | histone deacetylase inhibitors |
CHEBI has role | CHEBI:63726 | neuroprotective agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Absence seizure | indication | 79631006 | |
Epilepsy | indication | 84757009 | DOID:1826 |
Bipolar affective disorder, current episode manic | indication | 191618007 | |
Epilepsy characterized by intractable complex partial seizures | indication | 442481002 | |
Migraine Prevention | indication | ||
Bipolar disorder | off-label use | 13746004 | DOID:3312 |
Mixed bipolar I disorder | off-label use | 16506000 | DOID:3312 |
Myoclonic seizure | off-label use | 37356005 | |
Bipolar disorder in remission | off-label use | 85248005 | |
Seizure disorder | off-label use | 128613002 | |
Bipolar affective disorder, current episode depression | off-label use | 191627008 | DOID:3312 |
Tonic-clonic epilepsy | off-label use | 352818000 | DOID:7725 |
Simple partial seizure | off-label use | 117891000119100 | |
Rapid Cycling Bipolar Affective Disorder | off-label use | ||
Suicidal thoughts | contraindication | 6471006 | |
Hyperammonemia | contraindication | 9360008 | |
Arginase deficiency | contraindication | 23501004 | DOID:9278 |
Depressive disorder | contraindication | 35489007 | |
Congenital hyperammonemia, type I | contraindication | 62522004 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Organic mental disorder | contraindication | 111479008 | |
Hypoalbuminemia | contraindication | 119247004 | |
Disease of blood AND/OR blood-forming organ | contraindication | 191124002 | DOID:74 |
Acute pancreatitis | contraindication | 197456007 | DOID:2913 |
Chronic pancreatitis | contraindication | 235494005 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Poisoning by sodium valproate | contraindication | 241754000 | |
Pregnancy, function | contraindication | 289908002 | |
Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
Hypothermia | contraindication | 386689009 | |
Citrullinemia | contraindication | 398680004 | DOID:9273 |
Porphyria | contraindication | 418470004 | |
Ornithine Carbamyltransferase Deficiency | contraindication | ||
Arginosuccinate Lyase Deficiency | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 4.97 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Succinate-semialdehyde dehydrogenase, mitochondrial | Enzyme | INHIBITOR | CHEMBL | CHEMBL | |||||
Histone deacetylase 2 | Enzyme | IC50 | 4.21 | CHEMBL | |||||
Histone deacetylase 1 | Enzyme | INHIBITOR | IC50 | 6.40 | IUPHAR | ||||
Alcohol dehydrogenase [NADP(+)] | Enzyme | IC50 | 4.30 | CHEMBL | |||||
UDP-glucuronosyltransferase 1-5 | Enzyme | WOMBAT-PK | |||||||
Aldose reductase | Enzyme | IC50 | 4.25 | CHEMBL | |||||
Alcohol dehydrogenase [NADP(+)] | Enzyme | IC50 | 4.05 | CHEMBL | |||||
Alcohol dehydrogenase [NADP(+)] | Enzyme | IC50 | 4.30 | CHEMBL | |||||
Aldose reductase | Enzyme | IC50 | 4.24 | CHEMBL | |||||
Aldose reductase-related protein 1 | Enzyme | IC50 | 4.25 | CHEMBL |
ID | Source |
---|---|
4022507 | VUID |
N0000147028 | NUI |
D00304 | KEGG_DRUG |
76584-70-8 | SECONDARY_CAS_RN |
1069-66-5 | SECONDARY_CAS_RN |
4018723 | VANDF |
4018724 | VANDF |
4018728 | VANDF |
4022507 | VANDF |
C0042291 | UMLSCUI |
CHEBI:39867 | CHEBI |
2PP | PDB_CHEM_ID |
CHEMBL109 | ChEMBL_ID |
DB00313 | DRUGBANK_ID |
CHEMBL2105613 | ChEMBL_ID |
CHEMBL433 | ChEMBL_ID |
D014635 | MESH_DESCRIPTOR_UI |
3121 | PUBCHEM_CID |
3300 | INN_ID |
7009 | IUPHAR_LIGAND_ID |
33433-82-8 | SECONDARY_CAS_RN |
614OI1Z5WI | UNII |
11118 | RXNORM |
147344 | MMSL |
17039 | MMSL |
203066 | MMSL |
255547 | MMSL |
3118 | MMSL |
4624 | MMSL |
5661 | MMSL |
5662 | MMSL |
942 | MMSL |
d00083 | MMSL |
d03833 | MMSL |
001622 | NDDF |
001623 | NDDF |
001624 | NDDF |
006036 | NDDF |
007107 | NDDF |
13965000 | SNOMEDCT_US |
387080000 | SNOMEDCT_US |
387481005 | SNOMEDCT_US |
5641004 | SNOMEDCT_US |
CHEMBL2315212 | ChEMBL_ID |
5132 | INN_ID |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
DepakoteER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-3826 | TABLET, EXTENDED RELEASE | 250 mg | ORAL | NDA | 31 sections |
DepakoteER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-3826 | TABLET, EXTENDED RELEASE | 250 mg | ORAL | NDA | 31 sections |
DepakoteSprinkles | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6114 | CAPSULE | 125 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6212 | TABLET, DELAYED RELEASE | 125 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6212 | TABLET, DELAYED RELEASE | 125 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6214 | TABLET, DELAYED RELEASE | 250 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6214 | TABLET, DELAYED RELEASE | 250 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6215 | TABLET, DELAYED RELEASE | 500 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-6215 | TABLET, DELAYED RELEASE | 500 mg | ORAL | NDA | 31 sections |
DepakoteER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7126 | TABLET, EXTENDED RELEASE | 500 mg | ORAL | NDA | 31 sections |
DepakoteER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7126 | TABLET, EXTENDED RELEASE | 500 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7325 | TABLET, DELAYED RELEASE | 125 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7325 | TABLET, DELAYED RELEASE | 125 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7327 | TABLET, DELAYED RELEASE | 500 mg | ORAL | NDA | 31 sections |
Depakote | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7327 | TABLET, DELAYED RELEASE | 500 mg | ORAL | NDA | 31 sections |
DepakoteER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7401 | TABLET, EXTENDED RELEASE | 250 mg | ORAL | NDA | 31 sections |
DepakoteER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7402 | TABLET, EXTENDED RELEASE | 500 mg | ORAL | NDA | 31 sections |
DepakoteER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0074-7402 | TABLET, EXTENDED RELEASE | 500 mg | ORAL | NDA | 31 sections |
VALPROIC ACID | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-0675 | SOLUTION | 250 mg | ORAL | ANDA | 31 sections |
VALPROIC ACID | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-1350 | SOLUTION | 500 mg | ORAL | ANDA | 31 sections |
VALPROIC ACID | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0121-4675 | SOLUTION | 250 mg | ORAL | ANDA | 31 sections |
Valproate Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9637 | INJECTION | 100 mg | INTRAVENOUS | ANDA | 27 sections |
Valproate Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9637 | INJECTION | 100 mg | INTRAVENOUS | ANDA | 27 sections |
Valproate Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9785 | INJECTION | 500 mg | INTRAVENOUS | ANDA | 29 sections |
Valproate Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9785 | INJECTION | 500 mg | INTRAVENOUS | ANDA | 29 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-0472 | TABLET, FILM COATED, EXTENDED RELEASE | 250 mg | ORAL | ANDA | 29 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-0472 | TABLET, FILM COATED, EXTENDED RELEASE | 250 mg | ORAL | ANDA | 29 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-0473 | TABLET, FILM COATED, EXTENDED RELEASE | 500 mg | ORAL | ANDA | 29 sections |
Divalproex Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-0473 | TABLET, FILM COATED, EXTENDED RELEASE | 500 mg | ORAL | ANDA | 29 sections |
VALPROIC ACID | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-5250 | SOLUTION | 250 mg | ORAL | ANDA | 30 sections |