tripamide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
diuretics, sulfamoylbenzoic acid derivatives 2760 73803-48-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • E614
  • normonal
  • tripamide
  • toripamide
  • Molecular weight: 369.86
  • Formula: C16H20ClN3O3S
  • CLOGP: 2.48
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 92.50
  • ALOGS: -3.57
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None PMDA EISAI CO., LTD

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D004232 Diuretics
MeSH PA D049990 Membrane Transport Modulators
MeSH PA D045283 Natriuretic Agents
MeSH PA D049994 Sodium Potassium Chloride Symporter Inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Essential hypertension indication 59621000 DOID:10825




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.68 acidic
pKa2 10.41 acidic
pKa3 4.09 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01895 KEGG_DRUG
C0077241 UMLSCUI
CHEBI:32264 CHEBI
CHEMBL2104484 ChEMBL_ID
DB15959 DRUGBANK_ID
C031282 MESH_SUPPLEMENTAL_RECORD_UI
5282210 PUBCHEM_CID
4936 INN_ID
G36A0E9CVT UNII
008144 NDDF

Pharmaceutical products:

None