tolonidine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antihypertensives, clonidine derivatives 2700 4201-22-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tolonidine mononitrate
  • tolonidine monohydrochloride
  • tolonidine nitrate
  • tolonidine
  • Molecular weight: 209.68
  • Formula: C10H12ClN3
  • CLOGP: 1.97
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 36.42
  • ALOGS: -2.44
  • ROTB: 1

Drug dosage:

DoseUnitRoute
0.75 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C02AC04 CARDIOVASCULAR SYSTEM
ANTIHYPERTENSIVES
ANTIADRENERGIC AGENTS, CENTRALLY ACTING
Imidazoline receptor agonists

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.95 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07168 KEGG_DRUG
57524-15-9 SECONDARY_CAS_RN
C0076803 UMLSCUI
CHEBI:134879 CHEBI
CHEMBL304253 ChEMBL_ID
DB13429 DRUGBANK_ID
72138 PUBCHEM_CID
3265 INN_ID
C011558 MESH_SUPPLEMENTAL_RECORD_UI
I4O795Q03O UNII
005731 NDDF
005732 NDDF

Pharmaceutical products:

None