Molfile
Inchi
Smiles
Synonyms:
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tolazoline monohydrochloride
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benzalolin
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tolazoline
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benzazoline
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benzidazol
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benzolin
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benzylimidazoline
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imidaline
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imidalin
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phenylmethylimidazoline
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priscoline
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vasodil
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tolazoline hydrochloride
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tolazoline HCl
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A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
- Molecular weight: 160.22
- Formula: C10H12N2
- CLOGP: 2.65
- LIPINSKI: 0
- HAC: 2
- HDO: 1
- TPSA: 24.39
- ALOGS: -2.07
- ROTB: 2
- Status: OFM
Legend: OFP - off patent OFM - off market ONP - on patent
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