tiliquinol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
quinoline derivatives 2664 5541-67-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tiliquinol
  • 8-Hydroxy-5-methylquinoline
  • Molecular weight: 159.19
  • Formula: C10H9NO
  • CLOGP: 2.58
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 33.12
  • ALOGS: -2.01
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC P01AA30 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
Hydroxyquinoline derivatives

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.34 acidic
pKa2 4.52 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Catechol O-methyltransferase Enzyme IC50 4.35 CHEMBL

External reference:

IDSource
C0049301 UMLSCUI
CHEBI:134789 CHEBI
CHEMBL1410814 ChEMBL_ID
71208 PUBCHEM_CID
5009 INN_ID
813OG1OGVG UNII
15850 RXNORM
005355 NDDF
735056008 SNOMEDCT_US

Pharmaceutical products:

None