thonzylamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	2642	91-85-0

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

thonzylamine
neohetramine

major descriptor (72-84); file-maintained to PYRIMIDINES

Molecular weight: 286.38
Formula: C16H22N4O
CLOGP: 2.46
LIPINSKI: 0
HAC: 5
HDO: 0
TPSA: 41.49
ALOGS: -2.59
ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	D04AA01	DERMATOLOGICALS ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC. ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC. Antihistamines for topical use
ATC	R01AC06	RESPIRATORY SYSTEM NASAL PREPARATIONS DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE Antiallergic agents, excl. corticosteroids
ATC	R06AC06	RESPIRATORY SYSTEM ANTIHISTAMINES FOR SYSTEMIC USE ANTIHISTAMINES FOR SYSTEMIC USE Substituted ethylene diamines
MeSH PA	D018494	Histamine Agents
MeSH PA	D006633	Histamine Antagonists
MeSH PA	D018377	Neurotransmitter Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	7.8	Basic
pKa2	1.88	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
D08587	KEGG_DRUG
C0175162	UMLSCUI
CHEBI:104017	CHEBI
CHEMBL1623738	ChEMBL_ID
DB11235	DRUGBANK_ID
C100145	MESH_SUPPLEMENTAL_RECORD_UI
5457	PUBCHEM_CID
4200	INN_ID
R79646H5Z8	UNII
1360721	RXNORM
d08090	MMSL
004792	NDDF
363553005	SNOMEDCT_US

Pharmaceutical products:

None