terizidone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2602 | 25683-71-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
minor descriptor (1975-1984); on-line & Index Medicus search OXAZOLES (1975-1984); RN given refers to parent cpd without isomeric designation
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Myelosuppression | 71.12 | 50.76 | 19 | 529 | 17436 | 56274083 |
| Polyneuropathy | 61.73 | 50.76 | 16 | 532 | 13034 | 56278485 |
| Myopathy | 56.10 | 50.76 | 14 | 534 | 9798 | 56281721 |
| Neuropathy peripheral | 53.73 | 50.76 | 24 | 524 | 102869 | 56188650 |
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Myelosuppression | 71.74 | 58.23 | 20 | 427 | 14900 | 31681997 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Myelosuppression | 138.15 | 47.45 | 39 | 968 | 30106 | 70897331 |
| Polyneuropathy | 113.14 | 47.45 | 31 | 976 | 21384 | 70906053 |
| Drug resistance | 71.62 | 47.45 | 25 | 982 | 38165 | 70889272 |
| Anaemia | 67.28 | 47.45 | 51 | 956 | 403372 | 70524065 |
| Electrocardiogram QT prolonged | 55.78 | 47.45 | 26 | 981 | 83491 | 70843946 |
| Psychotic disorder | 53.14 | 47.45 | 20 | 987 | 37681 | 70889756 |
| Bicytopenia | 52.28 | 47.45 | 12 | 995 | 4016 | 70923421 |
| Neuropathy peripheral | 50.97 | 47.45 | 28 | 979 | 126868 | 70800569 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | J04AK03 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIMYCOBACTERIALS DRUGS FOR TREATMENT OF TUBERCULOSIS Other drugs for treatment of tuberculosis |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 7.06 | acidic |
| pKa2 | 7.66 | acidic |
| pKa3 | 3.32 | Basic |
| pKa4 | 2.72 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07247 | KEGG_DRUG |
| C0145184 | UMLSCUI |
| CHEBI:135278 | CHEBI |
| CHEMBL2107553 | ChEMBL_ID |
| DB12954 | DRUGBANK_ID |
| C100142 | MESH_SUPPLEMENTAL_RECORD_UI |
| 65720 | PUBCHEM_CID |
| 1707 | INN_ID |
| 1199LEX5N8 | UNII |
| 57047 | RXNORM |
| 005992 | NDDF |
Pharmaceutical products:
None