terfenadine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2600 50679-08-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • terfenadine
  • ternadin
  • racemic terfenadine
  • seldane
A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
  • Molecular weight: 471.69
  • Formula: C32H41NO2
  • CLOGP: 6.07
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 2
  • TPSA: 43.70
  • ALOGS: -6.01
  • ROTB: 9

Drug dosage:

DoseUnitRoute
0.12 g O

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

terfenadine