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2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
terconazole 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
systemic antifungal agents, miconazole derivatives
2599
67915-31-5
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
terconazole
terazol
termayazole
triaconazole
R-42470
Molecular weight: 532.47
Formula: C26H31Cl2N5O3
CLOGP: 4.89
LIPINSKI: 1
HAC: 8
HDO: 0
TPSA: 64.88
ALOGS: -4.66
ROTB: 8
Status: OFP
Legend:
OFP - off patent
OFM - off market
ONP - on patent
Drug dosage:
Dose
Unit
Route
80
mg
V
ADMET properties:
None
Approvals:
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Date
Agency
Company
Orphan
Dec. 31, 1987
FDA
JANSSEN PHARMS
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FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
G01AG02
GENITO URINARY SYSTEM AND SEX HORMONES
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Triazole derivatives
CHEBI has role
CHEBI:149553
anticoronaviral drug
FDA CS
M0002083
Azoles
FDA EPC
N0000175487
Azole Antifungal
MeSH PA
D000890
Anti-Infective Agents
MeSH PA
D000935
Antifungal Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Candidal vulvovaginitis
indication
72605008
DOID:2272
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
8.72
Basic
pKa2
3.04
Basic
pKa3
1.55
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Sodium/nucleoside cotransporter 1
Transporter
O00337
S28A1_HUMAN
Ki
5.37
DRUG MATRIX
Alpha-2A adrenergic receptor
GPCR
P08913
ADA2A_HUMAN
Ki
6.43
DRUG MATRIX
Sigma non-opioid intracellular receptor 1
Membrane receptor
Q99720
SGMR1_HUMAN
Ki
6.67
DRUG MATRIX
Sodium-dependent serotonin transporter
Transporter
P31645
SC6A4_HUMAN
Ki
5.22
DRUG MATRIX
Sodium-dependent noradrenaline transporter
Transporter
P23975
SC6A2_HUMAN
Ki
4.60
DRUG MATRIX
5-hydroxytryptamine receptor 2A
GPCR
P28223
5HT2A_HUMAN
Ki
5.63
DRUG MATRIX
5-hydroxytryptamine receptor 2C
GPCR
P28335
5HT2C_HUMAN
Ki
5.44
DRUG MATRIX
Alpha-2B adrenergic receptor
GPCR
P18089
ADA2B_HUMAN
Ki
5.90
DRUG MATRIX
D(3) dopamine receptor
GPCR
P35462
DRD3_HUMAN
Ki
5.80
DRUG MATRIX
Muscarinic acetylcholine receptor M1
GPCR
P11229
ACM1_HUMAN
Ki
5.86
DRUG MATRIX
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External reference:
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ID
Source
002931
NDDF
0KJ2VE664U
UNII
25860005
SNOMEDCT_US
37806
RXNORM
387140007
SNOMEDCT_US
4019521
VUID
4019521
VANDF
441383
PUBCHEM_CID
46326
MMSL
4815
INN_ID
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
Terconazole
HUMAN PRESCRIPTION DRUG LABEL
1
0168-0346
CREAM
4 mg
VAGINAL
ANDA
21 sections
Terconazole
HUMAN PRESCRIPTION DRUG LABEL
1
0713-0552
SUPPOSITORY
80 mg
VAGINAL
ANDA
24 sections
Terconazole
HUMAN PRESCRIPTION DRUG LABEL
1
0713-0552
SUPPOSITORY
80 mg
VAGINAL
ANDA
24 sections
Terconazole
HUMAN PRESCRIPTION DRUG LABEL
1
21695-844
CREAM
4 mg
VAGINAL
ANDA
22 sections
TERCONAZOLE
HUMAN PRESCRIPTION DRUG LABEL
1
21695-933
CREAM
8 mg
VAGINAL
NDA
21 sections
Terconazole
HUMAN PRESCRIPTION DRUG LABEL
1
45802-717
SUPPOSITORY
80 mg
VAGINAL
ANDA
20 sections
Terconazole
HUMAN PRESCRIPTION DRUG LABEL
1
45802-717
SUPPOSITORY
80 mg
VAGINAL
ANDA
20 sections
Terconazole
HUMAN PRESCRIPTION DRUG LABEL
1
50090-0917
CREAM
4 mg
VAGINAL
ANDA
23 sections
Terconazole
HUMAN PRESCRIPTION DRUG LABEL
1
50090-0917
CREAM
4 mg
VAGINAL
ANDA
23 sections
Terconazole
HUMAN PRESCRIPTION DRUG LABEL
1
50090-1196
CREAM
8 mg
VAGINAL
ANDA
23 sections
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Structure 🔎
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L1000
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terconazole