talaporfin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| benzoporphyrin derivatives | 2555 | 110230-98-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
effective tumor localizer that brings about the selective degradation of tumor tissue following light exposure; structure given in first source
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Oct. 26, 2003 | PMDA | Meiji Seika Pharm |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000970 | Antineoplastic Agents |
| MeSH PA | D003879 | Dermatologic Agents |
| MeSH PA | D017319 | Photosensitizing Agents |
| MeSH PA | D011838 | Radiation-Sensitizing Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Primary malignant neoplasm of brain | indication | 93727008 | DOID:1319 |
| Malignant tumor of lung | indication | 363358000 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 2.04 | acidic |
| pKa2 | 3.67 | acidic |
| pKa3 | 4.62 | acidic |
| pKa4 | 6.6 | acidic |
| pKa5 | 12.24 | acidic |
| pKa6 | 13.64 | acidic |
| pKa7 | 7.57 | Basic |
| pKa8 | 7.09 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01985 | KEGG_DRUG |
| 220201-34-3 | SECONDARY_CAS_RN |
| C0245194 | UMLSCUI |
| CHEBI:135875 | CHEBI |
| CHEMBL2111186 | ChEMBL_ID |
| CHEMBL2107806 | ChEMBL_ID |
| CHEMBL1697761 | ChEMBL_ID |
| DB11812 | DRUGBANK_ID |
| C053434 | MESH_SUPPLEMENTAL_RECORD_UI |
| 7974 | INN_ID |
| P4ROX5ELT2 | UNII |
| 5488036 | PUBCHEM_CID |
Pharmaceutical products:
None