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tipepidine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 253 | 5169-78-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2B,AKT2,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,ITK,JAK2,MAP3K21,MAP3K7,MAPK10,MAPK7,MET,NTRK2,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PRKDC,STK33,TEK,TTK | 33 | |||
| kinase-selectivity-class | AXL,GRK2,SIK2,STK33,TEK,TTK | 6 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Stevens-Johnson syndrome | 49.02 | 42.57 | 15 | 495 | 46886 | 110541903 |
| Abnormal behaviour | 42.98 | 42.57 | 13 | 497 | 39026 | 110549763 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | R05DB24 | RESPIRATORY SYSTEM COUGH AND COLD PREPARATIONS COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS Other cough suppressants |
| CHEBI has role | CHEBI:35469 | antidepressant |
| CHEBI has role | CHEBI:51177 | antitussive |
Related Drugs by ATC class:
R05DB Other cough suppressants 25 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 7.8 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01495 | KEGG_DRUG |
| 31139-87-4 | SECONDARY_CAS_RN |
| CHEBI:135141 | CHEBI |
| CHEMBL1899506 | ChEMBL_ID |
| C028458 | MESH_SUPPLEMENTAL_RECORD_UI |
| 1956 | INN_ID |
| DB13474 | DRUGBANK_ID |
| 2260ZP67IT | UNII |
| C0076714 | UMLSCUI |
| 5484 | PUBCHEM_CID |
| 006544 | NDDF |
| 14961000179107 | SNOMEDCT_US |
Pharmaceutical products:
None