benproperine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5236 2156-27-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cofrel
  • benproperine
  • benproperine phosphate
  • flaveric
  • benproperine dihydrogen phosphate
  • benproperine embonate
  • benproperine pamoate
  • tussafug
has antineoplastic activity; structure in first source
  • Molecular weight: 309.45
  • Formula: C21H27NO
  • CLOGP: 5.77
  • LIPINSKI: 1
  • HAC: 2
  • HDO: 0
  • TPSA: 12.47
  • ALOGS: -5.34
  • ROTB: 6

Drug dosage:

DoseUnitRoute
75 mg O

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None China Food and Drug Administration (CFDA)

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R05DB02 RESPIRATORY SYSTEM
COUGH AND COLD PREPARATIONS
COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
Other cough suppressants
CHEBI has role CHEBI:51177 anti-tussive

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Cough indication 49727002




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.92 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
3AA6IZ48YK UNII
19428-14-9 SECONDARY_CAS_RN
64238-92-2 SECONDARY_CAS_RN
C0772056 UMLSCUI
CHEBI:37560 CHEBI
CHEMBL2105910 ChEMBL_ID
2326 PUBCHEM_CID
DB13309 DRUGBANK_ID
D01427 KEGG_DRUG
3118 INN_ID
006729 NDDF
006730 NDDF
006731 NDDF
703110003 SNOMEDCT_US
714624000 SNOMEDCT_US
236749 RXNORM
C477447 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None