clobutinol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
686 14860-49-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • clobutinol
  • clobutinol hydrochloride
  • KAT 256
  • KAT-256
  • biotertussin
  • silomat
  • clobutinol HCl
was minor as SILOMAT mapped to AMINO ALCOHOLS (63-79)
  • Molecular weight: 255.79
  • Formula: C14H22ClNO
  • CLOGP: 3.28
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 23.47
  • ALOGS: -2.68
  • ROTB: 5

Drug dosage:

DoseUnitRoute
0.12 g O
0.12 g P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R05DB03 RESPIRATORY SYSTEM
COUGH AND COLD PREPARATIONS
COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
Other cough suppressants
MeSH PA D000996 Antitussive Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D019141 Respiratory System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Non-productive cough indication 409596002
Prolonged QT interval contraindication 111975006




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.21 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01608 KEGG_DRUG
1215-83-4 SECONDARY_CAS_RN
21247 RXNORM
C0055897 UMLSCUI
CHEBI:31416 CHEBI
CHEMBL1474889 ChEMBL_ID
DB09004 DRUGBANK_ID
C017135 MESH_SUPPLEMENTAL_RECORD_UI
26937 PUBCHEM_CID
2462 INN_ID
1NY2IX043A UNII
004340 NDDF
004341 NDDF
713478004 SNOMEDCT_US

Pharmaceutical products:

None