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sulfamoxole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| anti-infectives, sulfonamides | 2520 | 729-99-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A sulfanilamide antibacterial agent.
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 1 | g | O |
| 1 | g | P |
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,AKT3,ALK,AURKA,AURKB,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK1,CDK5,CDK9,CHEK1,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GRK3,GSK3B,ITK,JAK1,JAK2,KIT,MAP2K6,MAP3K1,MAP3K21,MAP3K7,MAP4K1,MAPK12,MAPK7,MAPK9,MARK4,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CD,PIM2,PRKCD,PRKDC,SGK1,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1 | 57 | |||
| kinase-selectivity-class | ACVR2A,AURKA,AXL,CAMK2D,CDK9,DDR1,DYRK1B,EPHB4,ERBB2,FGFR1,GRK2,JAK1,MAP2K3,MAP2K6,MAP3K7,MAP4K1,MAPK7,MARK4,NTRK3,PDK2,PDK4,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1 | 28 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | J01EC03 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE SULFONAMIDES AND TRIMETHOPRIM Intermediate-acting sulfonamides |
| ATC | J01EE04 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE SULFONAMIDES AND TRIMETHOPRIM Combinations of sulfonamides and trimethoprim, incl. derivatives |
| MeSH PA | D000890 | Anti-Infective Agents |
| CHEBI has role | CHEBI:33281 | antimicrobial agent |
| CHEBI has role | CHEBI:33282 | antibacterial agent |
| CHEBI has role | CHEBI:88188 | drug allergen |
Related Drugs by ATC class:
J01EC Intermediate-acting sulfonamides 2 drugs
J01EE Combinations of sulfonamides and trimethoprim, incl. derivatives 7 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 7.54 | acidic |
| pKa2 | 2.18 | Basic |
| pKa3 | 0.73 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| N0000166868 | NUI |
| D02516 | KEGG_DRUG |
| C0038700 | UMLSCUI |
| CHEBI:55546 | CHEBI |
| CHEMBL2105399 | ChEMBL_ID |
| DB08798 | DRUGBANK_ID |
| D013423 | MESH_DESCRIPTOR_UI |
| 12894 | PUBCHEM_CID |
| 12744 | IUPHAR_LIGAND_ID |
| 1277 | INN_ID |
| HGG82XE020 | UNII |
| 10183 | RXNORM |
| 005294 | NDDF |
| 50848005 | SNOMEDCT_US |
Pharmaceutical products:
None