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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
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L1000
FAQ
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
sulfacytine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
anti-infectives, sulfonamides
2499
17784-12-2
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
sulfacytine
renoquid
sulfacitine
Molecular weight: 294.33
Formula: C12H14N4O3S
CLOGP: -0.33
LIPINSKI: 0
HAC: 7
HDO: 2
TPSA: 104.86
ALOGS: -2.80
ROTB: 3
Status: OFM
Legend:
OFP - off patent
OFM - off market
ONP - on patent
Drug dosage:
None
ADMET properties:
None
Approvals:
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Date
Agency
Company
Orphan
Sept. 12, 1975
FDA
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FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Bacterial urinary infection
indication
312124009
Third trimester pregnancy
contraindication
41587001
Megaloblastic anemia due to folate deficiency
contraindication
85649008
DOID:14026
Kidney disease
contraindication
90708001
DOID:557
Anemia due to enzyme deficiency
contraindication
111577008
Deficiency of glucose-6-phosphate dehydrogenase
contraindication
124134002
DOID:2862
Disease of blood AND/OR blood-forming organ
contraindication
191124002
DOID:74
Disease of liver
contraindication
235856003
DOID:409
Breastfeeding (mother)
contraindication
413712001
Porphyria
contraindication
418470004
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
6.53
acidic
pKa2
3.37
Basic
pKa3
1.94
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase; Dihydropteroate synthetase
Kinase
Q25704_PLAFA
INHIBITOR
CHEMBL
CHEMBL
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External reference:
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entries
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ID
Source
002834
NDDF
2891
INN_ID
4019058
VUID
4019058
VANDF
5322
PUBCHEM_CID
71138001
SNOMEDCT_US
78902
RXNORM
C0262960
UMLSCUI
C100141
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:135230
CHEBI
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Pharmaceutical products:
None
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sulfacytine