sulfacytine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anti-infectives, sulfonamides 2499 17784-12-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • sulfacytine
  • renoquid
  • sulfacitine
  • Molecular weight: 294.33
  • Formula: C12H14N4O3S
  • CLOGP: -0.33
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 2
  • TPSA: 104.86
  • ALOGS: -2.80
  • ROTB: 3

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Sept. 12, 1975 FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Bacterial urinary infection indication 312124009
Third trimester pregnancy contraindication 41587001
Megaloblastic anemia due to folate deficiency contraindication 85649008 DOID:14026
Kidney disease contraindication 90708001 DOID:557
Anemia due to enzyme deficiency contraindication 111577008
Deficiency of glucose-6-phosphate dehydrogenase contraindication 124134002 DOID:2862
Disease of blood AND/OR blood-forming organ contraindication 191124002 DOID:74
Disease of liver contraindication 235856003 DOID:409
Breastfeeding (mother) contraindication 413712001
Porphyria contraindication 418470004




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.53 acidic
pKa2 3.37 Basic
pKa3 1.94 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase; Dihydropteroate synthetase Kinase INHIBITOR CHEMBL CHEMBL

External reference:

IDSource
4019058 VUID
N0000147326 NUI
D02519 KEGG_DRUG
4019058 VANDF
C0262960 UMLSCUI
CHEBI:135230 CHEBI
CHEMBL1201056 ChEMBL_ID
DB01298 DRUGBANK_ID
C100141 MESH_SUPPLEMENTAL_RECORD_UI
5322 PUBCHEM_CID
2891 INN_ID
T795873AJP UNII
78902 RXNORM
002834 NDDF
71138001 SNOMEDCT_US

Pharmaceutical products:

None