DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
sulconazole 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
systemic antifungal agents, miconazole derivatives
2495
61318-90-9
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
sulconazole mononitrate
sulconazole
sulconazole nitrate
Molecular weight: 397.74
Formula: C18H15Cl3N2S
CLOGP: 6.27
LIPINSKI: 1
HAC: 2
HDO: 0
TPSA: 17.82
ALOGS: -5.49
ROTB: 6
Status: OFP
Legend:
OFP - off patent
OFM - off market
ONP - on patent
Drug dosage:
None
ADMET properties:
None
Approvals:
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Date
Agency
Company
Orphan
Aug. 30, 1985
FDA
RANBAXY
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FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
D01AC09
DERMATOLOGICALS
ANTIFUNGALS FOR DERMATOLOGICAL USE
ANTIFUNGALS FOR TOPICAL USE
Imidazole and triazole derivatives
FDA CS
M0002083
Azoles
FDA EPC
N0000175487
Azole Antifungal
MeSH PA
D000890
Anti-Infective Agents
MeSH PA
D000935
Antifungal Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Tinea pedis
indication
6020002
DOID:12403
Pityriasis versicolor
indication
56454009
DOID:9060
Tinea corporis
indication
84849002
Tinea cruris
indication
399029005
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
5.02
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Alpha-2A adrenergic receptor
GPCR
P08913
ADA2A_HUMAN
Ki
5.82
DRUG MATRIX
Cytochrome P450 3A4
Enzyme
P08684
CP3A4_HUMAN
IC50
7.16
DRUG MATRIX
Sodium-dependent serotonin transporter
Transporter
P31645
SC6A4_HUMAN
Ki
7.13
DRUG MATRIX
Sodium-dependent noradrenaline transporter
Transporter
P23975
SC6A2_HUMAN
Ki
5.70
DRUG MATRIX
5-hydroxytryptamine receptor 2A
GPCR
P28223
5HT2A_HUMAN
Ki
5.95
DRUG MATRIX
5-hydroxytryptamine receptor 2B
GPCR
P41595
5HT2B_HUMAN
Ki
5.72
DRUG MATRIX
5-hydroxytryptamine receptor 2C
GPCR
P28335
5HT2C_HUMAN
Ki
5.84
DRUG MATRIX
Alpha-2B adrenergic receptor
GPCR
P18089
ADA2B_HUMAN
Ki
5.79
DRUG MATRIX
D(3) dopamine receptor
GPCR
P35462
DRD3_HUMAN
Ki
5.98
DRUG MATRIX
Muscarinic acetylcholine receptor M1
GPCR
P11229
ACM1_HUMAN
Ki
6.05
DRUG MATRIX
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External reference:
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ID
Source
002933
NDDF
004964
NDDF
108920000
SNOMEDCT_US
108921001
SNOMEDCT_US
358697
MMSL
37319
RXNORM
373448004
SNOMEDCT_US
4019499
VANDF
4019938
VUID
4019938
VANDF
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
Exelderm
HUMAN PRESCRIPTION DRUG LABEL
1
69489-711
CREAM
10 mg
TOPICAL
NDA
18 sections
Exelderm
HUMAN PRESCRIPTION DRUG LABEL
1
69489-711
CREAM
10 mg
TOPICAL
NDA
18 sections
Exelderm
HUMAN PRESCRIPTION DRUG LABEL
1
69489-721
SOLUTION
10 mg
TOPICAL
NDA
17 sections
Exelderm
HUMAN PRESCRIPTION DRUG LABEL
1
69489-721
SOLUTION
10 mg
TOPICAL
NDA
17 sections
Sulconazole Nitrate
HUMAN PRESCRIPTION DRUG LABEL
1
72143-311
CREAM
10 mg
TOPICAL
NDA
18 sections
Sulconazole Nitrate
HUMAN PRESCRIPTION DRUG LABEL
1
72143-321
SOLUTION
10 mg
TOPICAL
NDA
17 sections
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sulconazole