Molfile
Inchi
Smiles
Synonyms:
-
rotigotine
-
neupro
-
leganto
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(S)-(-)-Rotigotine
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Rotigotine is a non-ergoline dopamine agonist. The precise mechanism of action of rotigotine as a treatment for Parkinson's disease is unknown, although it is thought to be related to its ability to stimulate dopamine receptors within the caudate-putamen in the brain. The precise mechanism of action of rotigotine as a treatment for Restless Legs Syndrome is unknown but is thought to be related to its ability to stimulate dopamine receptors.
- Molecular weight: 315.48
- Formula: C19H25NOS
- CLOGP: 4.54
- LIPINSKI: 0
- HAC: 2
- HDO: 1
- TPSA: 23.47
- ALOGS: -4.54
- ROTB: 6
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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