ronifibrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
clofibrate derivatives, peroxisome proliferator activated receptor-alpha(PPAR-alpha) agonists 2401 42597-57-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ronifibrate
  • cloprane
  • Molecular weight: 377.82
  • Formula: C19H20ClNO5
  • CLOGP: 4.15
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 0
  • TPSA: 74.72
  • ALOGS: -4.39
  • ROTB: 10

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C10AB07 CARDIOVASCULAR SYSTEM
LIPID MODIFYING AGENTS
LIPID MODIFYING AGENTS, PLAIN
Fibrates
MeSH PA D000963 Antimetabolites
MeSH PA D000924 Anticholesteremic Agents
MeSH PA D000960 Hypolipidemic Agents
MeSH PA D057847 Lipid Regulating Agents
CHEBI has role CHEBI:25212 metabolites
CHEBI has role CHEBI:35620 vasodilator agents
CHEBI has role CHEBI:35679 antilipemic drugs
CHEBI has role CHEBI:50247 antidotes
CHEBI has role CHEBI:75771 Mus musculus metabolites
CHEBI has role CHEBI:76924 plant metabolites
CHEBI has role CHEBI:76971 Escherichia coli metabolites
CHEBI has role CHEBI:84087 human urinary metabolites
CHEBI has role CHEBI:84264 nicotinamide deaminase inhibitors
CHEBI has role CHEBI:24527 herbicides
CHEBI has role CHEBI:35610 antineoplastic agents
CHEBI has role CHEBI:35821 anticholesteremic drugs
CHEBI has role CHEBI:70782 PPAR-alpha agonist
CHEBI has role CHEBI:83399 marine xenobiotic metabolites

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.03 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07186 KEGG_DRUG
4017661 VANDF
4019440 VANDF
C2347974 UMLSCUI
CHEBI:135588 CHEBI
CHEBI:34648 CHEBI
CHEBI:15940 CHEBI
NIO PDB_CHEM_ID
CHEMBL153983 ChEMBL_ID
DB13460 DRUGBANK_ID
68671 PUBCHEM_CID
5856 INN_ID
W86I18X716 UNII
DB00627 DRUGBANK_ID
7393 RXNORM
2275 MMSL
5169 MMSL
7161 MMSL
d00314 MMSL
001052 NDDF
273943001 SNOMEDCT_US
63639004 SNOMEDCT_US
C0009003 UMLSCUI
C0027996 UMLSCUI
2439 INN_ID
2797 PUBCHEM_CID
938 PUBCHEM_CID
D002995 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None