romurtide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
peptides and glycopeptides 2400 78113-36-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • romurtide
  • muroctasin
  • muroctasine
  • nopia
a synthetic muramyl dipeptide analog; stimulates chemotactic mobility, phagocytic activity & superoxide production by neutrophils in mice; used for the prophylaxis of leukocytopenia during radiation therapy; structure given in first source
  • Molecular weight: 887.13
  • Formula: C43H78N6O13
  • CLOGP: 4.03
  • LIPINSKI: 3
  • HAC: 19
  • HDO: 10
  • TPSA: 305.04
  • ALOGS: -4.78
  • ROTB: 35

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000276 Adjuvants, Immunologic
MeSH PA D007155 Immunologic Factors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.99 acidic
pKa2 11.44 acidic
pKa3 12.64 acidic
pKa4 13.07 acidic
pKa5 13.09 acidic
pKa6 13.5 acidic
pKa7 13.63 acidic
pKa8 13.96 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01722 KEGG_DRUG
C0067246 UMLSCUI
CHEBI:32106 CHEBI
CHEMBL1908331 ChEMBL_ID
C036866 MESH_SUPPLEMENTAL_RECORD_UI
6406 INN_ID
SUP956TPT6 UNII
6917906 PUBCHEM_CID

Pharmaceutical products:

None