rocuronium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| neuromuscular blocking agents with rigid structure | 2396 | 119302-91-9 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Rocuronium bromide is a nondepolarizing neuromuscular blocking agent with a rapid to intermediate onset depending on dose and intermediate duration. It acts by competing for cholinergic receptors at the motor end-plate. This action is antagonized by acetylcholinesterase inhibitors, such as neostigmine and edrophonium.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 3 | Benet LZ, Broccatelli F, Oprea TI |
| EoM (Fraction excreted unchanged in urine) | 17 % | Benet LZ, Broccatelli F, Oprea TI |
| MRTD (Maximum Recommended Therapeutic Daily Dose) | 0.38 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
| Vd (Volume of distribution) | 0.21 L/kg | Lombardo F, Berellini G, Obach RS |
| CL (Clearance) | 3.70 mL/min/kg | Lombardo F, Berellini G, Obach RS |
| fu (Fraction unbound in plasma) | 0.54 % | Lombardo F, Berellini G, Obach RS |
| t_half (Half-life) | 1.60 hours | Lombardo F, Berellini G, Obach RS |
| S (Water solubility) | 122 mg/mL | Bocci G, Oprea TI, Benet LZ |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| March 17, 1994 | FDA | ORGANON USA INC |
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Anaphylactic reaction | 1481.02 | 30.01 | 516 | 10296 | 65584 | 63412626 |
| Anaphylactic shock | 1231.55 | 30.01 | 352 | 10460 | 23281 | 63454929 |
| Hypotension | 544.63 | 30.01 | 414 | 10398 | 272190 | 63206020 |
| Cardiac arrest | 456.53 | 30.01 | 249 | 10563 | 92296 | 63385914 |
| Neuromuscular block prolonged | 434.58 | 30.01 | 76 | 10736 | 466 | 63477744 |
| Bronchospasm | 404.54 | 30.01 | 140 | 10672 | 17140 | 63461070 |
| Serotonin syndrome | 318.77 | 30.01 | 135 | 10677 | 28547 | 63449663 |
| Myoglobin urine present | 259.23 | 30.01 | 52 | 10760 | 720 | 63477490 |
| Circulatory collapse | 239.49 | 30.01 | 102 | 10710 | 21836 | 63456374 |
| Delayed recovery from anaesthesia | 223.74 | 30.01 | 46 | 10766 | 725 | 63477485 |
| Stress cardiomyopathy | 214.99 | 30.01 | 75 | 10737 | 9375 | 63468835 |
| Tachycardia | 209.66 | 30.01 | 168 | 10644 | 117988 | 63360222 |
| Drug interaction | 204.55 | 30.01 | 222 | 10590 | 228909 | 63249301 |
| Recurrence of neuromuscular blockade | 197.64 | 30.01 | 32 | 10780 | 112 | 63478098 |
| Bradycardia | 185.50 | 30.01 | 129 | 10683 | 73098 | 63405112 |
| Amylase increased | 162.36 | 30.01 | 55 | 10757 | 6290 | 63471920 |
| Toxic encephalopathy | 156.52 | 30.01 | 54 | 10758 | 6525 | 63471685 |
| Kounis syndrome | 147.03 | 30.01 | 38 | 10774 | 1692 | 63476518 |
| Therapeutic product effect prolonged | 137.54 | 30.01 | 27 | 10785 | 332 | 63477878 |
| Troponin increased | 133.86 | 30.01 | 54 | 10758 | 10067 | 63468143 |
| Unwanted awareness during anaesthesia | 120.88 | 30.01 | 24 | 10788 | 314 | 63477896 |
| Hypoventilation | 112.99 | 30.01 | 39 | 10773 | 4715 | 63473495 |
| Blood lactate dehydrogenase increased | 104.80 | 30.01 | 59 | 10753 | 23057 | 63455153 |
| Fatigue | 104.79 | 30.01 | 14 | 10798 | 888014 | 62590196 |
| Wrist surgery | 103.24 | 30.01 | 25 | 10787 | 850 | 63477360 |
| Airway peak pressure increased | 99.80 | 30.01 | 20 | 10792 | 275 | 63477935 |
| Blood potassium increased | 97.56 | 30.01 | 52 | 10760 | 18257 | 63459953 |
| Pulseless electrical activity | 95.57 | 30.01 | 39 | 10773 | 7482 | 63470728 |
| Neuromuscular blockade | 93.65 | 30.01 | 19 | 10793 | 279 | 63477931 |
| Ventricular tachycardia | 93.30 | 30.01 | 52 | 10760 | 19927 | 63458283 |
| Finger deformity | 91.09 | 30.01 | 38 | 10774 | 7707 | 63470503 |
| Paralysis | 88.42 | 30.01 | 40 | 10772 | 9860 | 63468350 |
| Haemodynamic instability | 88.04 | 30.01 | 39 | 10773 | 9151 | 63469059 |
| Oxygen saturation decreased | 87.89 | 30.01 | 91 | 10721 | 88494 | 63389716 |
| Blood creatine phosphokinase increased | 87.39 | 30.01 | 58 | 10754 | 30372 | 63447838 |
| Blood pressure decreased | 85.55 | 30.01 | 78 | 10734 | 64944 | 63413266 |
| Hyperthermia malignant | 84.08 | 30.01 | 21 | 10791 | 813 | 63477397 |
| Premature delivery | 82.84 | 30.01 | 56 | 10756 | 30225 | 63447985 |
| Maternal exposure during delivery | 80.79 | 30.01 | 23 | 10789 | 1477 | 63476733 |
| Breast cancer recurrent | 78.19 | 30.01 | 29 | 10783 | 4312 | 63473898 |
| Hypoxia | 77.24 | 30.01 | 71 | 10741 | 59721 | 63418489 |
| Arthralgia | 74.71 | 30.01 | 6 | 10806 | 569704 | 62908506 |
| Urticaria | 72.28 | 30.01 | 113 | 10699 | 165689 | 63312521 |
| Diarrhoea | 71.86 | 30.01 | 17 | 10795 | 715349 | 62762861 |
| Nausea | 68.77 | 30.01 | 30 | 10782 | 854441 | 62623769 |
| Headache | 67.75 | 30.01 | 13 | 10799 | 633228 | 62844982 |
| Anaphylactoid reaction | 67.53 | 30.01 | 25 | 10787 | 3698 | 63474512 |
| Tenosynovitis | 67.41 | 30.01 | 37 | 10775 | 13758 | 63464452 |
| Apnoea | 67.19 | 30.01 | 31 | 10781 | 7991 | 63470219 |
| Limb operation | 65.59 | 30.01 | 25 | 10787 | 4006 | 63474204 |
| Ventricular fibrillation | 64.04 | 30.01 | 34 | 10778 | 11833 | 63466377 |
| Dystonia | 59.20 | 30.01 | 34 | 10778 | 13785 | 63464425 |
| Anticholinergic syndrome | 58.38 | 30.01 | 20 | 10792 | 2362 | 63475848 |
| Anaesthetic complication | 58.14 | 30.01 | 19 | 10793 | 1941 | 63476269 |
| Type I hypersensitivity | 57.97 | 30.01 | 21 | 10791 | 2921 | 63475289 |
| Exposure during pregnancy | 56.93 | 30.01 | 98 | 10714 | 155449 | 63322761 |
| Procedural hypotension | 54.12 | 30.01 | 16 | 10796 | 1174 | 63477036 |
| Endotracheal intubation complication | 53.91 | 30.01 | 13 | 10799 | 434 | 63477776 |
| Vasoplegia syndrome | 52.55 | 30.01 | 17 | 10795 | 1682 | 63476528 |
| Anaphylactoid shock | 52.18 | 30.01 | 12 | 10800 | 325 | 63477885 |
| Airway complication of anaesthesia | 51.75 | 30.01 | 11 | 10801 | 205 | 63478005 |
| Alanine aminotransferase increased | 48.36 | 30.01 | 73 | 10739 | 103697 | 63374513 |
| Postoperative delirium | 47.73 | 30.01 | 9 | 10803 | 88 | 63478122 |
| Respiratory acidosis | 47.20 | 30.01 | 23 | 10789 | 6692 | 63471518 |
| Subcutaneous emphysema | 45.38 | 30.01 | 13 | 10799 | 853 | 63477357 |
| Fall | 44.19 | 30.01 | 7 | 10805 | 392327 | 63085883 |
| Carcinoid crisis | 44.02 | 30.01 | 10 | 10802 | 256 | 63477954 |
| Hyperreflexia | 43.74 | 30.01 | 21 | 10791 | 5913 | 63472297 |
| Skin test positive | 42.94 | 30.01 | 12 | 10800 | 720 | 63477490 |
| Angioedema | 41.74 | 30.01 | 46 | 10766 | 47919 | 63430291 |
| Diabetes insipidus | 41.70 | 30.01 | 16 | 10796 | 2609 | 63475601 |
| Laryngeal oedema | 41.44 | 30.01 | 20 | 10792 | 5698 | 63472512 |
| Vomiting | 41.30 | 30.01 | 22 | 10790 | 559595 | 62918615 |
| Altered state of consciousness | 40.67 | 30.01 | 34 | 10778 | 25196 | 63453014 |
| Muscle rigidity | 40.65 | 30.01 | 25 | 10787 | 11475 | 63466735 |
| Abdominal discomfort | 40.31 | 30.01 | 4 | 10808 | 320881 | 63157329 |
| Pulmonary oedema | 39.96 | 30.01 | 48 | 10764 | 54825 | 63423385 |
| Tracheal injury | 39.08 | 30.01 | 7 | 10805 | 50 | 63478160 |
| Neuromuscular blocking therapy | 38.39 | 30.01 | 5 | 10807 | 0 | 63478210 |
| Pain | 38.27 | 30.01 | 42 | 10770 | 740586 | 62737624 |
| Therapeutic product effect increased | 36.94 | 30.01 | 12 | 10800 | 1203 | 63477007 |
| Clonus | 35.98 | 30.01 | 17 | 10795 | 4619 | 63473591 |
| Respiratory arrest | 35.00 | 30.01 | 35 | 10777 | 32610 | 63445600 |
| Pain in extremity | 34.95 | 30.01 | 7 | 10805 | 331479 | 63146731 |
| Torsade de pointes | 34.86 | 30.01 | 24 | 10788 | 13327 | 63464883 |
| Atrioventricular dissociation | 34.74 | 30.01 | 8 | 10804 | 218 | 63477992 |
| Isoimmune haemolytic disease | 34.26 | 30.01 | 6 | 10806 | 37 | 63478173 |
| Myasthenic syndrome | 33.62 | 30.01 | 8 | 10804 | 252 | 63477958 |
| Dizziness | 33.03 | 30.01 | 16 | 10796 | 429909 | 63048301 |
| Multiple organ dysfunction syndrome | 32.41 | 30.01 | 44 | 10768 | 56708 | 63421502 |
| Unresponsive to stimuli | 32.17 | 30.01 | 34 | 10778 | 33782 | 63444428 |
| Post procedural stroke | 32.17 | 30.01 | 6 | 10806 | 55 | 63478155 |
| Decreased appetite | 31.86 | 30.01 | 3 | 10809 | 251049 | 63227161 |
| Death | 31.84 | 30.01 | 12 | 10800 | 374369 | 63103841 |
| Pruritus | 31.73 | 30.01 | 11 | 10801 | 361442 | 63116768 |
| Pulmonary hypertensive crisis | 31.40 | 30.01 | 8 | 10804 | 336 | 63477874 |
| Irregular breathing | 31.30 | 30.01 | 8 | 10804 | 340 | 63477870 |
| Cardiac output decreased | 31.18 | 30.01 | 10 | 10802 | 962 | 63477248 |
| Allergy test positive | 31.12 | 30.01 | 9 | 10803 | 611 | 63477599 |
| Neurodevelopmental disorder | 31.01 | 30.01 | 7 | 10805 | 174 | 63478036 |
| Erythema | 30.70 | 30.01 | 82 | 10730 | 175669 | 63302541 |
| Muscle twitching | 30.66 | 30.01 | 26 | 10786 | 19642 | 63458568 |
| Coronary artery embolism | 30.60 | 30.01 | 7 | 10805 | 185 | 63478025 |
| Maternal exposure during pregnancy | 30.07 | 30.01 | 94 | 10718 | 219968 | 63258242 |
| Mydriasis | 30.06 | 30.01 | 21 | 10791 | 11935 | 63466275 |
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Anaphylactic shock | 998.58 | 23.20 | 306 | 9426 | 15635 | 34931564 |
| Anaphylactic reaction | 765.61 | 23.20 | 300 | 9432 | 32001 | 34915198 |
| Hyperthermia malignant | 463.36 | 23.20 | 110 | 9622 | 2067 | 34945132 |
| Neuromuscular block prolonged | 310.25 | 23.20 | 61 | 9671 | 440 | 34946759 |
| Bronchospasm | 279.43 | 23.20 | 107 | 9625 | 10624 | 34936575 |
| Hypotension | 271.88 | 23.20 | 320 | 9412 | 221329 | 34725870 |
| Recurrence of neuromuscular blockade | 238.01 | 23.20 | 43 | 9689 | 182 | 34947017 |
| Cardiac arrest | 232.56 | 23.20 | 201 | 9531 | 95958 | 34851241 |
| Bradycardia | 186.93 | 23.20 | 160 | 9572 | 75258 | 34871941 |
| Delayed recovery from anaesthesia | 162.70 | 23.20 | 39 | 9693 | 762 | 34946437 |
| Kounis syndrome | 114.50 | 23.20 | 38 | 9694 | 2480 | 34944719 |
| Neuromuscular blockade | 108.91 | 23.20 | 23 | 9709 | 245 | 34946954 |
| Negative pressure pulmonary oedema | 106.27 | 23.20 | 22 | 9710 | 211 | 34946988 |
| Pulseless electrical activity | 103.31 | 23.20 | 47 | 9685 | 7164 | 34940035 |
| Respiratory depression | 102.40 | 23.20 | 61 | 9671 | 16184 | 34931015 |
| Tachycardia | 94.36 | 23.20 | 117 | 9615 | 84655 | 34862544 |
| Anaesthetic complication | 93.80 | 23.20 | 27 | 9705 | 1093 | 34946106 |
| Blood pressure decreased | 88.10 | 23.20 | 89 | 9643 | 51426 | 34895773 |
| Circulatory collapse | 87.95 | 23.20 | 61 | 9671 | 20977 | 34926222 |
| Endotracheal intubation complication | 84.50 | 23.20 | 20 | 9712 | 369 | 34946830 |
| Electrocardiogram ST segment elevation | 84.17 | 23.20 | 37 | 9695 | 5201 | 34941998 |
| Hypoventilation | 78.03 | 23.20 | 31 | 9701 | 3383 | 34943816 |
| Fatigue | 77.83 | 23.20 | 7 | 9725 | 370646 | 34576553 |
| Oxygen saturation decreased | 77.77 | 23.20 | 85 | 9647 | 53733 | 34893466 |
| Haemodynamic instability | 76.76 | 23.20 | 42 | 9690 | 9481 | 34937718 |
| Arteriospasm coronary | 71.38 | 23.20 | 29 | 9703 | 3353 | 34943846 |
| Procedural hypotension | 67.09 | 23.20 | 20 | 9712 | 916 | 34946283 |
| Airway complication of anaesthesia | 66.82 | 23.20 | 14 | 9718 | 143 | 34947056 |
| Ventricular fibrillation | 61.42 | 23.20 | 51 | 9681 | 22903 | 34924296 |
| Hypoxia | 61.16 | 23.20 | 76 | 9656 | 55019 | 34892180 |
| Ventricular tachycardia | 58.86 | 23.20 | 53 | 9679 | 26526 | 34920673 |
| Diabetes insipidus | 58.02 | 23.20 | 24 | 9708 | 2904 | 34944295 |
| Respiratory arrest | 56.42 | 23.20 | 53 | 9679 | 27990 | 34919209 |
| Multiple organ dysfunction syndrome | 55.49 | 23.20 | 86 | 9646 | 76480 | 34870719 |
| Serotonin syndrome | 54.81 | 23.20 | 45 | 9687 | 19888 | 34927311 |
| Respiratory acidosis | 51.29 | 23.20 | 26 | 9706 | 5024 | 34942175 |
| Hypercapnia | 49.42 | 23.20 | 24 | 9708 | 4231 | 34942968 |
| Airway peak pressure increased | 47.77 | 23.20 | 8 | 9724 | 19 | 34947180 |
| Drug ineffective | 46.95 | 23.20 | 250 | 9482 | 456501 | 34490698 |
| Intensive care unit acquired weakness | 44.70 | 23.20 | 15 | 9717 | 1012 | 34946187 |
| Unwanted awareness during anaesthesia | 44.63 | 23.20 | 8 | 9724 | 32 | 34947167 |
| Pulmonary alveolar haemorrhage | 44.19 | 23.20 | 27 | 9705 | 7485 | 34939714 |
| Rhabdomyolysis | 43.13 | 23.20 | 72 | 9660 | 68091 | 34879108 |
| Respiratory failure | 43.09 | 23.20 | 94 | 9638 | 108478 | 34838721 |
| Death | 41.96 | 23.20 | 30 | 9702 | 398019 | 34549180 |
| Burkholderia test positive | 40.83 | 23.20 | 14 | 9718 | 1009 | 34946190 |
| Allergy test negative | 40.62 | 23.20 | 9 | 9723 | 122 | 34947077 |
| Diarrhoea | 40.29 | 23.20 | 30 | 9702 | 389882 | 34557317 |
| Cardio-respiratory arrest | 39.90 | 23.20 | 62 | 9670 | 55211 | 34891988 |
| Brain oedema | 39.67 | 23.20 | 32 | 9700 | 13789 | 34933410 |
| Urticaria | 39.61 | 23.20 | 66 | 9666 | 62311 | 34884888 |
| Acidosis | 39.42 | 23.20 | 29 | 9703 | 10916 | 34936283 |
| Hypoxic-ischaemic encephalopathy | 39.34 | 23.20 | 21 | 9711 | 4511 | 34942688 |
| Pulmonary oedema | 38.12 | 23.20 | 56 | 9676 | 47473 | 34899726 |
| Shock | 38.07 | 23.20 | 40 | 9692 | 24139 | 34923060 |
| Anaesthetic complication neurological | 36.73 | 23.20 | 10 | 9722 | 329 | 34946870 |
| Decreased appetite | 35.21 | 23.20 | 3 | 9729 | 166389 | 34780810 |
| Thyrotoxic crisis | 34.73 | 23.20 | 10 | 9722 | 405 | 34946794 |
| Hypotonic-hyporesponsive episode | 33.68 | 23.20 | 6 | 9726 | 23 | 34947176 |
| Arthralgia | 33.55 | 23.20 | 4 | 9728 | 170037 | 34777162 |
| Therapeutic product effect decreased | 32.39 | 23.20 | 44 | 9688 | 34699 | 34912500 |
| Trigemino-cardiac reflex | 32.08 | 23.20 | 8 | 9724 | 185 | 34947014 |
| Hyperkalaemia | 32.08 | 23.20 | 64 | 9668 | 69325 | 34877874 |
| Tachypnoea | 31.86 | 23.20 | 32 | 9700 | 18320 | 34928879 |
| Endotracheal intubation | 31.77 | 23.20 | 16 | 9716 | 3049 | 34944150 |
| Drug reaction with eosinophilia and systemic symptoms | 31.07 | 23.20 | 42 | 9690 | 32970 | 34914229 |
| Headache | 30.54 | 23.20 | 9 | 9723 | 200626 | 34746573 |
| Blood catecholamines increased | 30.45 | 23.20 | 5 | 9727 | 10 | 34947189 |
| Propofol infusion syndrome | 30.10 | 23.20 | 11 | 9721 | 955 | 34946244 |
| Therapeutic product effect prolonged | 29.69 | 23.20 | 8 | 9724 | 253 | 34946946 |
| Prinzmetal angina | 29.53 | 23.20 | 11 | 9721 | 1008 | 34946191 |
| Dizziness | 29.48 | 23.20 | 12 | 9720 | 218509 | 34728690 |
| Muscle rigidity | 29.44 | 23.20 | 24 | 9708 | 10494 | 34936705 |
| Fall | 29.28 | 23.20 | 10 | 9722 | 202875 | 34744324 |
| Acute respiratory distress syndrome | 29.06 | 23.20 | 36 | 9696 | 25933 | 34921266 |
| Laryngospasm | 28.56 | 23.20 | 12 | 9720 | 1509 | 34945690 |
| Apnoea | 27.07 | 23.20 | 19 | 9713 | 6645 | 34940554 |
| Product measured potency issue | 26.70 | 23.20 | 6 | 9726 | 87 | 34947112 |
| Anaphylactoid reaction | 26.65 | 23.20 | 13 | 9719 | 2312 | 34944887 |
| Catecholamine crisis | 25.67 | 23.20 | 5 | 9727 | 34 | 34947165 |
| Anaemia | 25.29 | 23.20 | 17 | 9715 | 233318 | 34713881 |
| Nausea | 25.00 | 23.20 | 35 | 9697 | 339873 | 34607326 |
| Oromandibular dystonia | 24.54 | 23.20 | 8 | 9724 | 493 | 34946706 |
| Procedural complication | 24.18 | 23.20 | 15 | 9717 | 4268 | 34942931 |
| Sinus arrest | 23.84 | 23.20 | 11 | 9721 | 1729 | 34945470 |
| Malaise | 23.79 | 23.20 | 11 | 9721 | 185814 | 34761385 |
| Metabolic acidosis | 23.52 | 23.20 | 43 | 9689 | 43637 | 34903562 |
| Atrioventricular block complete | 23.46 | 23.20 | 20 | 9712 | 9299 | 34937900 |
| Dehydration | 23.43 | 23.20 | 4 | 9728 | 129965 | 34817234 |
| Phaeochromocytoma crisis | 23.28 | 23.20 | 5 | 9727 | 58 | 34947141 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Anaphylactic shock | 2132.28 | 23.12 | 642 | 18823 | 35354 | 79689569 |
| Anaphylactic reaction | 2059.29 | 23.12 | 770 | 18695 | 82973 | 79641950 |
| Hypotension | 715.00 | 23.12 | 693 | 18772 | 439624 | 79285299 |
| Neuromuscular block prolonged | 708.03 | 23.12 | 134 | 19331 | 896 | 79724027 |
| Bronchospasm | 635.39 | 23.12 | 236 | 19229 | 24623 | 79700300 |
| Cardiac arrest | 630.18 | 23.12 | 436 | 19029 | 171660 | 79553263 |
| Hyperthermia malignant | 522.11 | 23.12 | 125 | 19340 | 2792 | 79722131 |
| Delayed recovery from anaesthesia | 353.37 | 23.12 | 82 | 19383 | 1591 | 79723332 |
| Recurrence of neuromuscular blockade | 352.33 | 23.12 | 62 | 19403 | 257 | 79724666 |
| Bradycardia | 327.12 | 23.12 | 268 | 19197 | 135289 | 79589634 |
| Serotonin syndrome | 315.50 | 23.12 | 173 | 19292 | 44854 | 79680069 |
| Circulatory collapse | 298.27 | 23.12 | 157 | 19308 | 37511 | 79687412 |
| Tachycardia | 275.71 | 23.12 | 274 | 19191 | 177494 | 79547429 |
| Kounis syndrome | 250.97 | 23.12 | 76 | 19389 | 4206 | 79720717 |
| Myoglobin urine present | 208.41 | 23.12 | 48 | 19417 | 899 | 79724024 |
| Stress cardiomyopathy | 203.43 | 23.12 | 83 | 19382 | 11083 | 79713840 |
| Pulseless electrical activity | 190.84 | 23.12 | 85 | 19380 | 14075 | 79710848 |
| Neuromuscular blockade | 180.30 | 23.12 | 39 | 19426 | 541 | 79724382 |
| Blood pressure decreased | 168.34 | 23.12 | 161 | 19304 | 99305 | 79625618 |
| Drug interaction | 158.73 | 23.12 | 327 | 19138 | 414856 | 79310067 |
| Fatigue | 157.05 | 23.12 | 21 | 19444 | 929706 | 78795217 |
| Hypoventilation | 153.48 | 23.12 | 60 | 19405 | 7164 | 79717759 |
| Haemodynamic instability | 153.48 | 23.12 | 78 | 19387 | 17304 | 79707619 |
| Oxygen saturation decreased | 146.90 | 23.12 | 169 | 19296 | 128878 | 79596045 |
| Ventricular tachycardia | 140.66 | 23.12 | 101 | 19364 | 41834 | 79683089 |
| Airway peak pressure increased | 134.61 | 23.12 | 28 | 19437 | 318 | 79724605 |
| Anaesthetic complication | 130.83 | 23.12 | 42 | 19423 | 2817 | 79722106 |
| Unwanted awareness during anaesthesia | 130.43 | 23.12 | 27 | 19438 | 299 | 79724624 |
| Airway complication of anaesthesia | 129.20 | 23.12 | 28 | 19437 | 392 | 79724531 |
| Procedural hypotension | 127.57 | 23.12 | 38 | 19427 | 1985 | 79722938 |
| Ventricular fibrillation | 121.29 | 23.12 | 83 | 19382 | 31843 | 79693080 |
| Hypoxia | 118.78 | 23.12 | 136 | 19329 | 103107 | 79621816 |
| Endotracheal intubation complication | 115.45 | 23.12 | 29 | 19436 | 793 | 79724130 |
| Electrocardiogram ST segment elevation | 115.03 | 23.12 | 51 | 19414 | 8346 | 79716577 |
| Therapeutic product effect prolonged | 114.98 | 23.12 | 27 | 19438 | 552 | 79724371 |
| Negative pressure pulmonary oedema | 114.64 | 23.12 | 23 | 19442 | 215 | 79724708 |
| Amylase increased | 109.86 | 23.12 | 54 | 19411 | 11155 | 79713768 |
| Diarrhoea | 106.78 | 23.12 | 41 | 19424 | 880448 | 78844475 |
| Arthralgia | 103.65 | 23.12 | 10 | 19455 | 571793 | 79153130 |
| Diabetes insipidus | 99.05 | 23.12 | 40 | 19425 | 5197 | 79719726 |
| Toxic encephalopathy | 97.11 | 23.12 | 50 | 19415 | 11390 | 79713533 |
| Arteriospasm coronary | 95.90 | 23.12 | 42 | 19423 | 6674 | 79718249 |
| Headache | 94.48 | 23.12 | 22 | 19443 | 653750 | 79071173 |
| Urticaria | 92.91 | 23.12 | 164 | 19301 | 185037 | 79539886 |
| Respiratory depression | 91.38 | 23.12 | 66 | 19399 | 27564 | 79697359 |
| Paralysis | 90.46 | 23.12 | 50 | 19415 | 13127 | 79711796 |
| Nausea | 90.16 | 23.12 | 62 | 19403 | 957134 | 78767789 |
| Respiratory acidosis | 89.47 | 23.12 | 47 | 19418 | 11153 | 79713770 |
| Troponin increased | 85.05 | 23.12 | 55 | 19410 | 19200 | 79705723 |
| Anaphylactoid reaction | 84.27 | 23.12 | 36 | 19429 | 5386 | 79719537 |
| Respiratory arrest | 80.40 | 23.12 | 84 | 19381 | 57466 | 79667457 |
| Apnoea | 79.22 | 23.12 | 44 | 19421 | 11660 | 79713263 |
| Multiple organ dysfunction syndrome | 75.73 | 23.12 | 118 | 19347 | 120128 | 79604795 |
| Pulmonary oedema | 73.68 | 23.12 | 99 | 19366 | 88155 | 79636768 |
| Fall | 73.24 | 23.12 | 15 | 19450 | 487614 | 79237309 |
| Anticholinergic syndrome | 73.21 | 23.12 | 29 | 19436 | 3582 | 79721341 |
| Maternal exposure during delivery | 70.83 | 23.12 | 22 | 19443 | 1324 | 79723599 |
| Hypercapnia | 69.97 | 23.12 | 37 | 19428 | 8898 | 79716025 |
| Vomiting | 65.44 | 23.12 | 41 | 19424 | 665787 | 79059136 |
| Muscle rigidity | 64.61 | 23.12 | 47 | 19418 | 19835 | 79705088 |
| Type I hypersensitivity | 64.41 | 23.12 | 28 | 19437 | 4370 | 79720553 |
| Pain in extremity | 64.36 | 23.12 | 7 | 19458 | 364531 | 79360392 |
| Dystonia | 63.74 | 23.12 | 48 | 19417 | 21351 | 79703572 |
| Wrist surgery | 63.26 | 23.12 | 18 | 19447 | 799 | 79724124 |
| Dizziness | 62.85 | 23.12 | 25 | 19440 | 526416 | 79198507 |
| Respiratory failure | 62.49 | 23.12 | 137 | 19328 | 180774 | 79544149 |
| Decreased appetite | 61.93 | 23.12 | 6 | 19459 | 342412 | 79382511 |
| Skin test positive | 60.99 | 23.12 | 19 | 19446 | 1155 | 79723768 |
| Anaphylactoid shock | 59.54 | 23.12 | 17 | 19448 | 764 | 79724159 |
| Laryngospasm | 57.08 | 23.12 | 25 | 19440 | 3972 | 79720951 |
| Postoperative delirium | 56.97 | 23.12 | 14 | 19451 | 349 | 79724574 |
| Carcinoid crisis | 56.63 | 23.12 | 15 | 19450 | 508 | 79724415 |
| Blood potassium increased | 56.43 | 23.12 | 51 | 19414 | 29224 | 79695699 |
| Blood lactate dehydrogenase increased | 56.18 | 23.12 | 58 | 19407 | 39112 | 79685811 |
| Trigemino-cardiac reflex | 55.82 | 23.12 | 13 | 19452 | 256 | 79724667 |
| Weight increased | 55.47 | 23.12 | 3 | 19462 | 277383 | 79447540 |
| Shock | 54.53 | 23.12 | 60 | 19405 | 43488 | 79681435 |
| Neutropenia | 52.13 | 23.12 | 5 | 19460 | 287705 | 79437218 |
| Death | 51.46 | 23.12 | 38 | 19427 | 566476 | 79158447 |
| Blood creatine phosphokinase increased | 50.42 | 23.12 | 71 | 19394 | 66019 | 79658904 |
| Malaise | 49.70 | 23.12 | 29 | 19436 | 489840 | 79235083 |
| Weight decreased | 49.17 | 23.12 | 13 | 19452 | 355185 | 79369738 |
| Anaesthetic complication neurological | 49.01 | 23.12 | 14 | 19451 | 630 | 79724293 |
| Pulmonary alveolar haemorrhage | 48.81 | 23.12 | 32 | 19433 | 11425 | 79713498 |
| Back pain | 48.54 | 23.12 | 8 | 19457 | 304172 | 79420751 |
| Laryngeal oedema | 48.12 | 23.12 | 28 | 19437 | 8101 | 79716822 |
| Angioedema | 46.99 | 23.12 | 74 | 19391 | 75961 | 79648962 |
| Pain | 46.92 | 23.12 | 62 | 19403 | 703740 | 79021183 |
| Procedural complication | 45.94 | 23.12 | 27 | 19438 | 7956 | 79716967 |
| Premature delivery | 45.46 | 23.12 | 41 | 19424 | 23426 | 79701497 |
| Pruritus | 45.04 | 23.12 | 20 | 19445 | 394628 | 79330295 |
| Finger deformity | 44.92 | 23.12 | 26 | 19439 | 7448 | 79717475 |
| Infusion related reaction | 44.48 | 23.12 | 3 | 19462 | 230234 | 79494689 |
| Endotracheal intubation | 44.15 | 23.12 | 22 | 19443 | 4675 | 79720248 |
| Erythema | 43.95 | 23.12 | 137 | 19328 | 223153 | 79501770 |
| Hypoxic-ischaemic encephalopathy | 43.83 | 23.12 | 26 | 19439 | 7794 | 79717129 |
| Abdominal discomfort | 43.76 | 23.12 | 5 | 19460 | 250722 | 79474201 |
| Acidosis | 43.23 | 23.12 | 37 | 19428 | 19725 | 79705198 |
| Vasoplegia syndrome | 43.23 | 23.12 | 20 | 19445 | 3610 | 79721313 |
| Subcutaneous emphysema | 42.02 | 23.12 | 16 | 19449 | 1778 | 79723145 |
| Cardio-respiratory arrest | 41.86 | 23.12 | 86 | 19379 | 108424 | 79616499 |
| Exposure during pregnancy | 41.21 | 23.12 | 82 | 19383 | 101050 | 79623873 |
| Anaesthetic complication pulmonary | 39.95 | 23.12 | 8 | 19457 | 74 | 79724849 |
| Asthenia | 39.54 | 23.12 | 40 | 19425 | 511649 | 79213274 |
| Thyrotoxic crisis | 39.51 | 23.12 | 14 | 19451 | 1270 | 79723653 |
| Clonus | 39.01 | 23.12 | 23 | 19442 | 6817 | 79718106 |
| Drug reaction with eosinophilia and systemic symptoms | 38.97 | 23.12 | 62 | 19403 | 64182 | 79660741 |
| Anaemia | 38.91 | 23.12 | 31 | 19434 | 444984 | 79279939 |
| Procedural haemorrhage | 38.30 | 23.12 | 20 | 19445 | 4686 | 79720237 |
| Limb operation | 38.09 | 23.12 | 18 | 19447 | 3408 | 79721515 |
| Upper airway obstruction | 38.06 | 23.12 | 14 | 19451 | 1414 | 79723509 |
| Drug ineffective | 37.87 | 23.12 | 416 | 19049 | 1080497 | 78644426 |
| Atrioventricular dissociation | 37.83 | 23.12 | 10 | 19455 | 336 | 79724587 |
| Rhabdomyolysis | 37.75 | 23.12 | 80 | 19385 | 103051 | 79621872 |
| Product measured potency issue | 37.70 | 23.12 | 9 | 19456 | 198 | 79724725 |
| Atrioventricular block second degree | 37.59 | 23.12 | 23 | 19442 | 7289 | 79717634 |
| Intensive care unit acquired weakness | 37.37 | 23.12 | 15 | 19450 | 1918 | 79723005 |
| Post procedural haemorrhage | 36.92 | 23.12 | 29 | 19436 | 13715 | 79711208 |
| Gait disturbance | 36.55 | 23.12 | 4 | 19461 | 207502 | 79517421 |
| Accelerated idioventricular rhythm | 36.48 | 23.12 | 9 | 19456 | 228 | 79724695 |
| Dehydration | 36.46 | 23.12 | 8 | 19457 | 248179 | 79476744 |
| Insomnia | 35.82 | 23.12 | 8 | 19457 | 245162 | 79479761 |
| Hypertensive crisis | 35.80 | 23.12 | 34 | 19431 | 20736 | 79704187 |
| Infection | 35.08 | 23.12 | 8 | 19457 | 241704 | 79483219 |
| Allergy test positive | 34.56 | 23.12 | 11 | 19454 | 717 | 79724206 |
| Tracheal injury | 34.46 | 23.12 | 7 | 19458 | 70 | 79724853 |
| Hypotonia | 34.24 | 23.12 | 27 | 19438 | 12843 | 79712080 |
| Sinus arrest | 34.15 | 23.12 | 17 | 19448 | 3605 | 79721318 |
| Atrioventricular block complete | 34.11 | 23.12 | 30 | 19435 | 16580 | 79708343 |
| Sinusitis | 33.85 | 23.12 | 4 | 19461 | 195497 | 79529426 |
| Propofol infusion syndrome | 33.59 | 23.12 | 14 | 19451 | 1969 | 79722954 |
| Allergy test negative | 33.42 | 23.12 | 9 | 19456 | 325 | 79724598 |
| Therapeutic product effect increased | 33.19 | 23.12 | 13 | 19452 | 1558 | 79723365 |
| Abdominal pain | 32.97 | 23.12 | 28 | 19437 | 389541 | 79335382 |
| Neuromuscular blocking therapy | 32.65 | 23.12 | 5 | 19460 | 6 | 79724917 |
| Torsade de pointes | 32.12 | 23.12 | 31 | 19434 | 19281 | 79705642 |
| Hyperdynamic left ventricle | 31.75 | 23.12 | 9 | 19456 | 394 | 79724529 |
| Acute respiratory distress syndrome | 31.63 | 23.12 | 46 | 19419 | 44021 | 79680902 |
| Hypothermia | 31.39 | 23.12 | 33 | 19432 | 22713 | 79702210 |
| Pneumonia | 31.35 | 23.12 | 72 | 19393 | 660174 | 79064749 |
| Abdominal pain upper | 31.32 | 23.12 | 8 | 19457 | 223811 | 79501112 |
| Hyperreflexia | 29.95 | 23.12 | 21 | 19444 | 8364 | 79716559 |
| Tachypnoea | 29.89 | 23.12 | 38 | 19427 | 32025 | 79692898 |
| Urinary tract infection | 29.63 | 23.12 | 15 | 19450 | 274497 | 79450426 |
| Coronary artery embolism | 29.06 | 23.12 | 8 | 19457 | 314 | 79724609 |
| Completed suicide | 28.74 | 23.12 | 12 | 19453 | 245755 | 79479168 |
| Phaeochromocytoma crisis | 28.70 | 23.12 | 8 | 19457 | 329 | 79724594 |
| Pulse absent | 28.62 | 23.12 | 22 | 19443 | 10081 | 79714842 |
| Pyrexia | 28.36 | 23.12 | 79 | 19386 | 678630 | 79046293 |
| Spinal cord infarction | 27.88 | 23.12 | 9 | 19456 | 614 | 79724309 |
| Tenosynovitis | 27.83 | 23.12 | 26 | 19439 | 15528 | 79709395 |
| Supraventricular tachycardia | 27.83 | 23.12 | 30 | 19435 | 21240 | 79703683 |
| Product administered to patient of inappropriate age | 27.36 | 23.12 | 17 | 19448 | 5536 | 79719387 |
| Dyskinesia | 26.86 | 23.12 | 43 | 19422 | 44730 | 79680193 |
| Post procedural complication | 26.71 | 23.12 | 31 | 19434 | 23798 | 79701125 |
| Post procedural stroke | 26.27 | 23.12 | 6 | 19459 | 108 | 79724815 |
| Paraplegia | 26.24 | 23.12 | 16 | 19449 | 5037 | 79719886 |
| COVID-19 treatment | 26.07 | 23.12 | 8 | 19457 | 462 | 79724461 |
| Renal injury | 25.97 | 23.12 | 26 | 19439 | 16901 | 79708022 |
| Febrile neutropenia | 25.87 | 23.12 | 12 | 19453 | 230987 | 79493936 |
| Blood catecholamines increased | 25.84 | 23.12 | 5 | 19460 | 38 | 79724885 |
| Muscle twitching | 25.74 | 23.12 | 31 | 19434 | 24733 | 79700190 |
| Prinzmetal angina | 25.35 | 23.12 | 11 | 19454 | 1709 | 79723214 |
| Irregular breathing | 25.31 | 23.12 | 8 | 19457 | 510 | 79724413 |
| Resuscitation | 24.81 | 23.12 | 12 | 19453 | 2392 | 79722531 |
| Catecholamine crisis | 24.71 | 23.12 | 5 | 19460 | 49 | 79724874 |
| Electrocardiogram ST segment depression | 24.20 | 23.12 | 15 | 19450 | 4863 | 79720060 |
| Fear | 23.64 | 23.12 | 28 | 19437 | 21958 | 79702965 |
| Altered state of consciousness | 23.48 | 23.12 | 40 | 19425 | 43782 | 79681141 |
| Mydriasis | 23.29 | 23.12 | 25 | 19440 | 17618 | 79707305 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | M03AC09 | MUSCULO-SKELETAL SYSTEM MUSCLE RELAXANTS MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS Other quaternary ammonium compounds |
| MeSH PA | D009465 | Neuromuscular Agents |
| MeSH PA | D009466 | Neuromuscular Blocking Agents |
| MeSH PA | D003473 | Neuromuscular Nondepolarizing Agents |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| CHEBI has role | CHEBI:51371 | muscle relaxants |
| FDA EPC | N0000175720 | Nondepolarizing Neuromuscular Blocker |
| FDA PE | N0000175732 | Neuromuscular Nondepolarizing Blockade |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Muscle relaxation, function | indication | 11977004 | |
| General anesthesia | indication | 50697003 | |
| Skeletal Muscle Relaxation for Endotracheal Intubation | indication | ||
| Respiratory acidosis | contraindication | 12326000 | |
| Alkalosis | contraindication | 21420006 | |
| Acidosis | contraindication | 51387008 | |
| Eaton-Lambert syndrome | contraindication | 56989000 | DOID:0050214 |
| Pulmonary hypertension | contraindication | 70995007 | DOID:6432 |
| Kidney disease | contraindication | 90708001 | DOID:557 |
| Myasthenia gravis | contraindication | 91637004 | DOID:437 |
| Respiratory alkalosis | contraindication | 111378004 | |
| Disease of liver | contraindication | 235856003 | DOID:409 |
| Disorder of electrolytes | contraindication | 237840007 | |
| Malignant hyperthermia | contraindication | 405501007 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 7.61 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Acetylcholine receptor | Ion channel | ANTAGONIST | IC50 | 7.77 | WOMBAT-PK | CHEMBL | |||
| Acetylcholine receptor; alpha1/beta1/delta/gamma | Ion channel | IC50 | 7.09 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D00765 | KEGG_DRUG |
| 4020866 | VANDF |
| C0209337 | UMLSCUI |
| CHEBI:8885 | CHEBI |
| RBR | PDB_CHEM_ID |
| CHEMBL1201244 | ChEMBL_ID |
| CHEMBL1200648 | ChEMBL_ID |
| D000077123 | MESH_DESCRIPTOR_UI |
| DB00728 | DRUGBANK_ID |
| 4003 | IUPHAR_LIGAND_ID |
| WRE554RFEZ | UNII |
| 441290 | PUBCHEM_CID |
| 151718 | RXNORM |
| 1460 | MMSL |
| 159147 | MMSL |
| 5433 | MMSL |
| d03766 | MMSL |
| 004442 | NDDF |
| 013418 | NDDF |
| 108449002 | SNOMEDCT_US |
| 108450002 | SNOMEDCT_US |
| 372494005 | SNOMEDCT_US |
| 6864 | INN_ID |
| 143558-00-3 | SECONDARY_CAS_RN |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9250 | INJECTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9250 | INJECTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9251 | INJECTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9251 | INJECTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| rocuronium bromide | Human Prescription Drug Label | 1 | 0409-3189 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| rocuronium bromide | Human Prescription Drug Label | 1 | 0409-7037 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-9558 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-9558 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-3220 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-3220 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| rocuronium bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 25021-662 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 27 sections |
| rocuronium bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 39822-4200 | SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| rocuronium bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 39822-4200 | SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43066-007 | INJECTION | 50 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43066-007 | INJECTION | 50 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43066-013 | INJECTION | 100 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium Bromide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43066-013 | INJECTION | 100 mg | INTRAVENOUS | ANDA | 26 sections |
| ROCURONIUM BROMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43547-530 | INJECTION | 50 mg | INTRAVENOUS | ANDA | 25 sections |
| ROCURONIUM BROMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43547-531 | INJECTION | 100 mg | INTRAVENOUS | ANDA | 25 sections |
| ROCURONIUM BROMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1354 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 18 sections |
| ROCURONIUM BROMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1355 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 18 sections |
| ROCURONIUM BROMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1545 | INJECTION, SOLUTION | 100 mg | INTRAVENOUS | ANDA | 17 sections |
| ROCURONIUM BROMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1546 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 17 sections |
| Rocuronium Bromide | Human Prescription Drug Label | 1 | 55150-225 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 25 sections |
| Rocuronium Bromide | Human Prescription Drug Label | 1 | 55150-225 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 25 sections |
| Rocuronium Bromide | Human Prescription Drug Label | 1 | 55150-226 | INJECTION, SOLUTION | 100 mg | INTRAVENOUS | ANDA | 25 sections |
| Rocuronium Bromide | Human Prescription Drug Label | 1 | 55150-226 | INJECTION, SOLUTION | 100 mg | INTRAVENOUS | ANDA | 25 sections |
| Rocuronium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 63323-426 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 63323-426 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| Rocuronium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 63323-426 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |