Molfile
Inchi
Smiles
Synonyms:
-
raloxifene
-
keoxifene
-
raloxifene hydrochloride
-
evista
-
raloxifene HCl
|
A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
- Molecular weight: 473.59
- Formula: C28H27NO4S
- CLOGP: 6.86
- LIPINSKI: 1
- HAC: 5
- HDO: 2
- TPSA: 70
- ALOGS: -5.97
- ROTB: 7
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
|