mepacrine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
acridine derivatives 2338 83-89-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • quinacrin
  • quinacrine
  • mepacrine
  • atabrine
  • acrinamine
  • acriquine
  • quinacrine dihydrochloride hydrate
  • quinacrine dihydrochloride
  • quinacrine hydrochloride
  • quinacrine HCl
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
  • Molecular weight: 399.96
  • Formula: C23H30ClN3O
  • CLOGP: 6.72
  • LIPINSKI: 1
  • HAC: 4
  • HDO: 1
  • TPSA: 37.39
  • ALOGS: -5.22
  • ROTB: 9

Drug dosage:

DoseUnitRoute
0.30 g O

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

mepacrine