prulifloxacin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibacterials, nalidixic acid derivatives 2325 123447-62-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • prulifloxacin
  • NM441
  • Molecular weight: 461.46
  • Formula: C21H20FN3O6S
  • CLOGP: 0.20
  • LIPINSKI: 0
  • HAC: 9
  • HDO: 1
  • TPSA: 99.62
  • ALOGS: -2.89
  • ROTB: 4

Drug dosage:

DoseUnitRoute
0.60 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01MA17 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
QUINOLONE ANTIBACTERIALS
Fluoroquinolones
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D059005 Topoisomerase II Inhibitors
MeSH PA D059003 Topoisomerase Inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Lower urinary tract infectious disease indication 4009004
Acute exacerbation of chronic bronchitis indication 425748003




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.72 acidic
pKa2 5.05 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01144 KEGG_DRUG
C0527129 UMLSCUI
CHEBI:32071 CHEBI
CHEBI:35044 CHEBI
CHEMBL422648 ChEMBL_ID
DB11892 DRUGBANK_ID
C074191 MESH_SUPPLEMENTAL_RECORD_UI
C074190 MESH_SUPPLEMENTAL_RECORD_UI
7249 INN_ID
J42298IESW UNII
65947 PUBCHEM_CID
015857 NDDF
703590007 SNOMEDCT_US
C1610779 UMLSCUI
CHEMBL345937 ChEMBL_ID
8346 INN_ID
112984-60-8 SECONDARY_CAS_RN
124225 PUBCHEM_CID
C38638H76Y UNII

Pharmaceutical products:

None