prothipendyl 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| vasodilators | 2315 | 303-69-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
a neuroleptic azaphenothiazine; RN given refers to parent cpd
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 0.24 | g | O |
| 0.24 | g | P |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Skin maceration | 59.00 | 55.59 | 7 | 590 | 41 | 50604486 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Labelled drug-drug interaction medication error | 85.00 | 42.75 | 25 | 896 | 22037 | 64475774 |
| Skin maceration | 57.36 | 42.75 | 7 | 914 | 43 | 64497768 |
| Drug interaction | 56.22 | 42.75 | 44 | 877 | 362039 | 64135772 |
| General physical health deterioration | 52.93 | 42.75 | 34 | 887 | 204391 | 64293420 |
| Helplessness | 51.63 | 42.75 | 8 | 913 | 318 | 64497493 |
| Restlessness | 48.44 | 42.75 | 19 | 902 | 39766 | 64458045 |
| Product prescribing error | 47.05 | 42.75 | 18 | 903 | 35251 | 64462560 |
| Disorientation | 45.45 | 42.75 | 20 | 901 | 55808 | 64442003 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | N05AX07 | NERVOUS SYSTEM PSYCHOLEPTICS ANTIPSYCHOTICS Other antipsychotics |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.01 | Basic |
| pKa2 | 2.74 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07313 | KEGG_DRUG |
| 1225-65-6 | SECONDARY_CAS_RN |
| C0139007 | UMLSCUI |
| CHEBI:135182 | CHEBI |
| CHEMBL2111030 | ChEMBL_ID |
| CHEMBL2107124 | ChEMBL_ID |
| DB12958 | DRUGBANK_ID |
| C069248 | MESH_SUPPLEMENTAL_RECORD_UI |
| 14670 | PUBCHEM_CID |
| 691 | INN_ID |
| 5O6VWA87VA | UNII |
| 236710 | RXNORM |
| 006649 | NDDF |
| 006650 | NDDF |
| 27766008 | SNOMEDCT_US |
Pharmaceutical products:
None